Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	disordered domain specific binding	HSP90AB4P HSP90AA1 HSP90AA2P HSP90AB3P	6.39e-06	39	62	4	GO:0097718
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSP90AB4P HSP90AA1 HSP90AA2P HSP90AB3P	7.08e-06	40	62	4	GO:0140662
GeneOntologyMolecularFunction	protein domain specific binding	CABP1 CACNA1C ZNF384 HSP90AB4P CRIM1 MYO7A EHMT2 NCAM1 HSP90AA1 HSP90AA2P EXOC4 HSP90AB3P	1.33e-05	875	62	12	GO:0019904
GeneOntologyMolecularFunction	unfolded protein binding	LMAN1 HSP90AB4P HSP90AA1 HSP90AA2P HSP90AB3P	4.48e-05	126	62	5	GO:0051082
GeneOntologyMolecularFunction	protein folding chaperone	HSP90AB4P HSP90AA1 HSP90AA2P HSP90AB3P	7.81e-05	73	62	4	GO:0044183
GeneOntologyMolecularFunction	calcium ion binding	CABP1 CLSTN3 HMCN1 UMODL1 TLL1 RCN2 LTBP1 PRKCSH EFCAB7	4.79e-04	749	62	9	GO:0005509
GeneOntologyBiologicalProcess	regulation of establishment of protein localization	CABP1 CACNA1C ZNF384 NEO1 LMAN1 PIK3R2 CEP295 EFCAB7 HSP90AA1 EXOC4	2.60e-05	674	61	10	GO:0070201
GeneOntologyBiologicalProcess	positive regulation of calcium-mediated signaling	PTPRJ NCAM1 PLCG2 EXOC4	5.49e-05	70	61	4	GO:0050850
GeneOntologyBiologicalProcess	regulation of protein localization	CABP1 CACNA1C ZNF384 CLSTN3 NEO1 LMAN1 PIK3R2 CEP295 EFCAB7 EIF2AK3 HSP90AA1 EXOC4	6.84e-05	1087	61	12	GO:0032880
GeneOntologyBiologicalProcess	regulation of protein import into nucleus	CABP1 PIK3R2 EFCAB7 HSP90AA1	9.71e-05	81	61	4	GO:0042306
GeneOntologyBiologicalProcess	cellular response to heat	HSP90AB4P HSP90AA1 HSP90AA2P HSP90AB3P	9.71e-05	81	61	4	GO:0034605
GeneOntologyBiologicalProcess	calcium-mediated signaling	CACNA1C PTPRJ NCAM1 PLCG2 EIF2AK3 EXOC4	1.33e-04	266	61	6	GO:0019722
GeneOntologyBiologicalProcess	regulation of protein localization to nucleus	CABP1 PIK3R2 EFCAB7 EIF2AK3 HSP90AA1	1.73e-04	176	61	5	GO:1900180
GeneOntologyBiologicalProcess	regulation of cellular localization	CABP1 CACNA1C ZNF384 CLSTN3 NEO1 LMAN1 PIK3R2 CEP295 EFCAB7 EIF2AK3 HSP90AA1 EXOC4	1.91e-04	1212	61	12	GO:0060341
Domain	Bet3	TRAPPC3L TRAPPC3	9.81e-06	2	59	2	IPR016721
Domain	-	GTF2IRD2B GTF2IRD2	5.86e-05	4	59	2	3.90.1460.10
Domain	Neural_cell_adh	HMCN1 NCAM1	5.86e-05	4	59	2	IPR009138
Domain	GTF2I	GTF2IRD2B GTF2IRD2	5.86e-05	4	59	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	5.86e-05	4	59	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	5.86e-05	4	59	2	IPR004212
Domain	TRAPP_component	TRAPPC3L TRAPPC3	9.75e-05	5	59	2	IPR007194
Domain	TRAPP	TRAPPC3L TRAPPC3	9.75e-05	5	59	2	PF04051
Domain	EGF_CA	HMCN1 UMODL1 TLL1 LTBP1	1.57e-04	86	59	4	PF07645
Domain	EGF_Ca-bd_CS	HMCN1 UMODL1 TLL1 LTBP1	2.50e-04	97	59	4	IPR018097
Domain	EGF_CA	HMCN1 UMODL1 TLL1 LTBP1	2.70e-04	99	59	4	PS01187
Domain	NO_sig/Golgi_transp_ligand-bd	TRAPPC3L TRAPPC3	2.71e-04	8	59	2	IPR024096
Domain	EF-hand-dom_pair	CABP1 CACNA1C RCN2 PRKCSH PLCG2 EFCAB7	2.84e-04	287	59	6	IPR011992
Domain	Heme_NO-bd	TRAPPC3L TRAPPC3	3.48e-04	9	59	2	IPR011644
Domain	EGF-type_Asp/Asn_hydroxyl_site	HMCN1 UMODL1 TLL1 LTBP1	3.51e-04	106	59	4	IPR000152
Domain	EGF_CA	HMCN1 UMODL1 TLL1 LTBP1	5.98e-04	122	59	4	SM00179
Domain	EGF-like_Ca-bd_dom	HMCN1 UMODL1 TLL1 LTBP1	6.35e-04	124	59	4	IPR001881
Domain	RNaseH-like_dom	GTF2IRD2B GTF2IRD2 ZMYM6	1.35e-03	69	59	3	IPR012337
Domain	Growth_fac_rcpt_	CRIM1 HMCN1 UMODL1 LTBP1	1.49e-03	156	59	4	IPR009030
Domain	fn3	NEO1 PTPRJ UMODL1 NCAM1	1.71e-03	162	59	4	PF00041
Domain	-	SMCHD1 HSP90AA1	1.80e-03	20	59	2	3.30.565.10
Domain	HATPase_C	SMCHD1 HSP90AA1	1.98e-03	21	59	2	IPR003594
Domain	EF_Hand_1_Ca_BS	CABP1 RCN2 PRKCSH EFCAB7	2.27e-03	175	59	4	IPR018247
Domain	EF-hand_7	CABP1 RCN2 EFCAB7	2.46e-03	85	59	3	PF13499
Domain	FN3	NEO1 PTPRJ UMODL1 NCAM1	2.77e-03	185	59	4	SM00060
Domain	EF-hand_5	RCN2 PRKCSH	2.81e-03	25	59	2	PF13202
Domain	cEGF	HMCN1 LTBP1	3.04e-03	26	59	2	IPR026823
Domain	cEGF	HMCN1 LTBP1	3.04e-03	26	59	2	PF12662
Domain	FN3	NEO1 PTPRJ UMODL1 NCAM1	3.60e-03	199	59	4	PS50853
Domain	ZnF_U1	ZFHX4 TUT7	3.77e-03	29	59	2	SM00451
Domain	Znf_U1	ZFHX4 TUT7	3.77e-03	29	59	2	IPR003604
Domain	ASX_HYDROXYL	HMCN1 UMODL1 LTBP1	3.90e-03	100	59	3	PS00010
Domain	EF_HAND_1	CABP1 RCN2 PRKCSH EFCAB7	3.94e-03	204	59	4	PS00018
Domain	FN3_dom	NEO1 PTPRJ UMODL1 NCAM1	4.29e-03	209	59	4	IPR003961
Domain	EF_HAND_2	CABP1 RCN2 PRKCSH EFCAB7	6.10e-03	231	59	4	PS50222
Domain	EF_hand_dom	CABP1 RCN2 PRKCSH EFCAB7	6.19e-03	232	59	4	IPR002048
Domain	EGF_3	HMCN1 UMODL1 TLL1 LTBP1	6.47e-03	235	59	4	PS50026
Domain	EGF	HMCN1 UMODL1 TLL1 LTBP1	6.47e-03	235	59	4	SM00181
Domain	EGF	HMCN1 TLL1 LTBP1	7.40e-03	126	59	3	PF00008
Domain	EGF-like_dom	HMCN1 UMODL1 TLL1 LTBP1	7.91e-03	249	59	4	IPR000742
Domain	EGF_1	HMCN1 UMODL1 TLL1 LTBP1	8.58e-03	255	59	4	PS00022
Domain	EGF-like_CS	HMCN1 UMODL1 TLL1 LTBP1	9.30e-03	261	59	4	IPR013032
Pubmed	The HSP90 family of genes in the human genome: insights into their divergence and evolution.	HSP90AB4P HSP90AA1 HSP90AA2P HSP90AB3P	1.75e-08	16	63	4	16269234
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF384 EHMT2 SMCHD1 ZNF451 ZFP1 HAT1 PHF8 MBD4 MGA	1.47e-06	608	63	9	36089195
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CUL4B TUT7 RCN2 CEP295 PHF8 MGA CAMSAP2 CFAP97 HSP90AA1 EXOC4	2.95e-06	853	63	10	28718761
Pubmed	Molecular mechanism for divergent regulation of Cav1.2 Ca2+ channels by calmodulin and Ca2+-binding protein-1.	CABP1 CACNA1C	3.23e-06	2	63	2	15980432
Pubmed	Structural basis for the differential effects of CaBP1 and calmodulin on Ca(V)1.2 calcium-dependent inactivation.	CABP1 CACNA1C	3.23e-06	2	63	2	21134641
Pubmed	Cloning and analysis of a human 86-kDa heat-shock-protein-encoding gene.	HSP90AA1 HSP90AA2P	3.23e-06	2	63	2	2591742
Pubmed	Inhibition of the Tumor Suppressor Gene SPINK5 via EHMT2 Induces the Oral Squamous Cell Carcinoma Development.	EHMT2 SPINK5	3.23e-06	2	63	2	37071303
Pubmed	Mfn2 modulates the UPR and mitochondrial function via repression of PERK.	MFN2 EIF2AK3	3.23e-06	2	63	2	23921556
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	3.23e-06	2	63	2	15388857
Pubmed	C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking.	LMAN1 TRAPPC3L TRAPPC3	3.78e-06	17	63	3	21525244
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CUL4B ZFHX4 EHMT2 SUPT4H1 PIK3R2 ZFP1 RCN2 CEP295 PHF8 ARID1A MGA	4.72e-06	1116	63	11	31753913
Pubmed	Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.	UBR1 SEMA6D MGA	6.32e-06	20	63	3	17082620
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CUL4B NEO1 ZNF451 TUT7 ZFP1 RCN2 SPG11 CEP295 MGA	6.69e-06	733	63	9	34672954
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	HSP90AB4P PIK3R2 RCN2 HAT1 NUDT13 HSP90AA1 HSP90AA2P HSP90AB3P	8.16e-06	565	63	8	33567341
Pubmed	Human transcription factor protein interaction networks.	ZFHX4 EHMT2 SMCHD1 ZNF451 MITF RCN2 PRKCSH TRAPPC3 PHF8 ARID1A MGA EXOC4	8.45e-06	1429	63	12	35140242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLSTN3 SEMA6D KIAA0513 ZNF451 MFN2 PHF8 CAMSAP2	8.99e-06	407	63	7	12693553
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CACNA1C GTF2IRD2B UMODL1 SMCHD1 ADAM7 GTF2IRD2 SPG11 CEP295 ARID1A CAMSAP2 PREX1 HSP90AA1	9.26e-06	1442	63	12	35575683
Pubmed	The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis.	HSP90AA1 HSP90AA2P	9.68e-06	3	63	2	20937816
Pubmed	Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness.	HSP90AA1 HSP90AA2P	9.68e-06	3	63	2	15146192
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	9.68e-06	3	63	2	15100712
Pubmed	PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation.	PIK3R2 EIF2AK3	9.68e-06	3	63	2	22493067
Pubmed	Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha.	EIF2AK3 HSP90AA1	9.68e-06	3	63	2	12446770
Pubmed	LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.	EHMT2 ARID1A MGA HSP90AA1	1.33e-05	79	63	4	26446488
Pubmed	The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha.	HSP90AA1 HSP90AA2P	1.93e-05	4	63	2	19234166
Pubmed	Mapping of the gene family for human heat-shock protein 90 alpha to chromosomes 1, 4, 11, and 14.	HSP90AA1 HSP90AA2P	1.93e-05	4	63	2	1740332
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2IRD2	1.93e-05	4	63	2	17823943
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	1.93e-05	4	63	2	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	1.93e-05	4	63	2	22899722
Pubmed	Heat shock protein 90 (Hsp90) selectively regulates the stability of KDM4B/JMJD2B histone demethylase.	HSP90AA1 HSP90AA2P	1.93e-05	4	63	2	23589305
Pubmed	Mammalian tolloid proteinases: role in growth factor signalling.	TLL1 LTBP1	1.93e-05	4	63	2	27391803
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2IRD2	1.93e-05	4	63	2	21328569
Pubmed	The role of mouse mutants in the identification of human hereditary hearing loss genes.	MYO7A MITF	1.93e-05	4	63	2	10320095
Pubmed	The neural cell adhesion molecule promotes FGFR-dependent phosphorylation and membrane targeting of the exocyst complex to induce exocytosis in growth cones.	NCAM1 EXOC4	1.93e-05	4	63	2	21389209
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	NEO1 LMAN1 HSP90AB4P CRIM1 PTPRJ SMCHD1 SPG11 LTBP1 PRKCSH CAMSAP2	1.97e-05	1061	63	10	33845483
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	PIK3R2 RCN2 TRAPPC3 HSP90AA1 EXOC4	2.10e-05	183	63	5	23956138
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	CUL4B HSP90AB4P MYO7A HAT1 PRKCSH ARID1A HSP90AA1 HSP90AA2P HSP90AB3P	2.11e-05	847	63	9	35235311
Pubmed	Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels.	CABP1 CACNA1C	3.22e-05	5	63	2	15140941
Pubmed	Cross-reactivity of anti-programmed death ligand 2 polyclonal antibody in mouse tissues.	HMCN1 NCAM1	3.22e-05	5	63	2	23090063
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF451 TUT7 CEP295 EXOC4	3.64e-05	102	63	4	11214970
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	HSP90AB4P RCN2 HAT1 HSP90AA1 HSP90AA2P HSP90AB3P	3.79e-05	344	63	6	36282215
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CUL4B EHMT2 ZNF451 ZFP1 RCN2 PRKCSH ARID1A CFAP97 HSP90AA1 EXOC4	4.05e-05	1155	63	10	20360068
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	CUL4B HAT1 MGA HSP90AA2P HSP90AB3P	4.53e-05	215	63	5	35973513
Pubmed	ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.	CACNA1C EIF2AK3	4.82e-05	6	63	2	16352659
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	EHMT2 SMCHD1 RCN2 LTBP1 PHF8 ARID1A MGA	5.03e-05	533	63	7	30554943
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CLSTN3 LMAN1 CRIM1 PTPRJ TLL1 TUT7 RCN2 LTBP1 PRKCSH EIF2AK3	5.62e-05	1201	63	10	35696571
Pubmed	Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.	CACNA1C PHF8	6.74e-05	7	63	2	21057379
Pubmed	AR-12 Inhibits Multiple Chaperones Concomitant With Stimulating Autophagosome Formation Collectively Preventing Virus Replication.	EIF2AK3 HSP90AA1	8.98e-05	8	63	2	27187154
Pubmed	Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.	NEO1 NCAM1	8.98e-05	8	63	2	26651291
Pubmed	The in vivo brain interactome of the amyloid precursor protein.	CLSTN3 RCN2 NCAM1	1.04e-04	50	63	3	17934213
Pubmed	A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.	HSP90AB4P HSP90AA1 HSP90AB3P	1.11e-04	51	63	3	36896912
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UBR1 ZNF384 SMCHD1 TUT7 PLCG2 PHF8 ARID1A MGA HSP90AA1 EXOC4	1.50e-04	1353	63	10	29467282
Pubmed	Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.	LMAN1 HSP90AB4P PRKCSH HSP90AA2P HSP90AB3P	1.62e-04	282	63	5	35007762
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	LMAN1 PIK3R2 MFN2 HSP90AA1	1.62e-04	150	63	4	32423001
Pubmed	Protein partners in the life history of activated fibroblast growth factor receptors.	RCN2 PLCG2 HSP90AA1	1.71e-04	59	63	3	18022941
Pubmed	The program for processing newly synthesized histones H3.1 and H4.	HAT1 HSP90AA1	1.76e-04	11	63	2	20953179
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNA1C NCAM1	1.76e-04	11	63	2	18809727
Pubmed	PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.	EHMT2 MGA	1.76e-04	11	63	2	35933409
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	EHMT2 HAT1 ARID1A MBD4	1.93e-04	157	63	4	30186101
Pubmed	Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.	NEO1 MITF	2.11e-04	12	63	2	31336386
Pubmed	Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity.	MITF NCAM1	2.49e-04	13	63	2	15576400
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	MYO7A MITF	2.90e-04	14	63	2	19320733
Pubmed	Defining brain wiring patterns and mechanisms through gene trapping in mice.	NEO1 CRIM1	2.90e-04	14	63	2	11242070
Pubmed	PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.	MYO7A MITF	2.90e-04	14	63	2	24875170
Pubmed	PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.	HSP90AA1 HSP90AA2P	2.90e-04	14	63	2	29178343
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LMAN1 SEMA6D HMCN1 LTBP1	2.93e-04	175	63	4	28071719
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CUL4B ZNF384 SMCHD1 ZNF451 ARID1A MBD4 MGA HSP90AA1	3.17e-04	954	63	8	36373674
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NEO1 LMAN1 EHMT2 PIK3R2 ZNF451 RCN2 SPG11 PRKCSH EIF2AK3 EXOC4	3.20e-04	1487	63	10	33957083
Pubmed	Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.	MYO7A MITF	3.34e-04	15	63	2	18715234
Pubmed	CAND1 enhances deneddylation of CUL1 by COP9 signalosome.	CUL4B HSP90AA1	3.81e-04	16	63	2	16036220
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	CUL4B ZNF384 SMCHD1 PHF8 ARID1A	3.88e-04	341	63	5	32971831
Pubmed	Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.	PREX1 EXOC4	4.32e-04	17	63	2	17903302
Pubmed	Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.	EIF2AK3 HSP90AA1	4.32e-04	17	63	2	32938586
Pubmed	Phosphoproteomic analysis of synaptosomes from human cerebral cortex.	NCAM1 HSP90AA1	4.32e-04	17	63	2	15822905
Pubmed	Interaction network of human early embryonic transcription factors.	ZFHX4 EHMT2 MITF ARID1A MGA	4.43e-04	351	63	5	38297188
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	PTPRJ TUT7 LTBP1 EIF2AK3	4.67e-04	198	63	4	20881960
Pubmed	The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.	CUL4B EHMT2 MFN2 ARID1A	4.76e-04	199	63	4	36688959
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CUL4B EHMT2 SMCHD1 ZNF451 HAT1 PHF8 MBD4 HSP90AA1	4.76e-04	1014	63	8	32416067
Pubmed	Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors.	TLL1 NCAM1	4.85e-04	18	63	2	19914233
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CLSTN3 CRIM1 EHMT2 ZNF451 ARID1A MBD4 PREX1 HSP90AA1 EXOC4	4.90e-04	1285	63	9	35914814
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	SMCHD1 ARID1A MGA EIF2AK3 TULP2	4.90e-04	359	63	5	35559673
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	ZNF384 SMCHD1 MGA	5.21e-04	86	63	3	37253089
Pubmed	Transcriptional fates of human-specific segmental duplications in brain.	GTF2IRD2B GTF2IRD2	5.41e-04	19	63	2	30228200
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	LMAN1 PTPRJ RCN2 LTBP1 PRKCSH PHF8 ARID1A HSP90AA1	5.95e-04	1049	63	8	27880917
Pubmed	Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.	EHMT2 PHF8	6.01e-04	20	63	2	36551904
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	CUL4B MYO7A ADAM7 HAT1 PRKCSH ARID1A HSP90AA1	6.14e-04	803	63	7	36517590
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	RCN2 LTBP1 ARID1A MGA EXOC4	6.19e-04	378	63	5	34315543
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CUL4B HSP90AB4P RCN2 HAT1 SPG11 TRAPPC3 HSP90AA1 HSP90AA2P HSP90AB3P	6.45e-04	1335	63	9	29229926
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ZNF384 ZFHX4 EHMT2 SMCHD1 MGA HSP90AA1	6.54e-04	583	63	6	29844126
Pubmed	CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex.	CUL4B HSP90AA1	6.63e-04	21	63	2	12481031
Pubmed	Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.	NEO1 NCAM1	7.29e-04	22	63	2	37823339
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	TTLL3 MITF NCAM1 HSP90AA1	8.58e-04	233	63	4	32290105
Pubmed	Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells.	MITF NCAM1	8.69e-04	24	63	2	30348676
Pubmed	Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1.	PIK3R2 PLCG2	8.69e-04	24	63	2	20624904
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KIAA0513 ZNF451 MGA	9.31e-04	105	63	3	9628581
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	SMCHD1 ZNF451 PHF8	9.57e-04	106	63	3	19394292
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	LMAN1 ZFHX4 EHMT2 MGA EXOC4	9.71e-04	418	63	5	34709266
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CUL4B HSP90AB4P RCN2 HAT1 HSP90AA1 EXOC4	1.04e-03	638	63	6	33239621
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	CRIM1 LTBP1	1.18e-03	28	63	2	33953184
Pubmed	Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.	PIK3R2 RCN2 PRKCSH HSP90AA1	1.21e-03	256	63	4	24189400
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	SEMA6D NCAM1 ZMYM6	1.27e-03	117	63	3	17145500
Interaction	GTF2IRD2 interactions	GTF2IRD2B GTF2IRD2 HSP90AA1	5.98e-06	12	62	3	int:GTF2IRD2
Interaction	CDKL4 interactions	HSP90AB4P HSP90AA1 HSP90AB3P	7.76e-06	13	62	3	int:CDKL4
Interaction	TWIST2 interactions	CUL4B EHMT2 PLCG2	1.83e-05	17	62	3	int:TWIST2
Interaction	AMHR2 interactions	UBR1 HSP90AB4P HSP90AA1 HSP90AB3P	2.65e-05	56	62	4	int:AMHR2
Interaction	ELK3 interactions	ZFHX4 EHMT2 SMCHD1 PHF8 MGA	3.40e-05	120	62	5	int:ELK3
Interaction	CACNA1A interactions	CABP1 CACNA1C CRIM1 EHMT2 LTBP1	3.82e-05	123	62	5	int:CACNA1A
Interaction	UNC45B interactions	HSP90AB4P HSP90AA1 HSP90AB3P	4.10e-05	22	62	3	int:UNC45B
Interaction	GUCY2D interactions	HSP90AB4P HSP90AA1 HSP90AB3P	4.70e-05	23	62	3	int:GUCY2D
Interaction	CCDC117 interactions	HSP90AB4P HSP90AA1 HSP90AB3P	6.85e-05	26	62	3	int:CCDC117
Interaction	RICTOR interactions	CUL4B LMAN1 EHMT2 HAT1 MGA PREX1 HSP90AA1 HSP90AA2P EXOC4 HSP90AB3P	9.87e-05	759	62	10	int:RICTOR
Interaction	STK35 interactions	HSP90AB4P HSP90AA1 HSP90AB3P	1.06e-04	30	62	3	int:STK35
Interaction	H3C3 interactions	ZNF384 EHMT2 SMCHD1 ZFP1 HAT1 PHF8 MBD4 MGA	1.32e-04	495	62	8	int:H3C3
Cytoband	16q24.1	KIAA0513 PLCG2	9.52e-04	33	63	2	16q24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	SEMA6D HSP90AB4P SPG11	1.89e-03	177	63	3	chr15q21
Cytoband	15q14	SPG11 MGA	2.09e-03	49	63	2	15q14
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTPRJ TLL1 SAMD5 NCAM1 LTBP1	7.34e-06	190	63	5	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 HMCN1 TLL1 SAMD5 LTBP1	7.34e-06	190	63	5	9b0ad888eb20acc011904d8593bc32bdef18d050
ToppCell	P15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CRIM1 HMCN1 PTPRJ TLL1 SAMD5	7.34e-06	190	63	5	d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 HMCN1 SAMD5 NCAM1 LTBP1	7.53e-06	191	63	5	fcdf3a747038e346a467eae8b7c293592658b53f
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	CABP1 CACNA1C CRIM1 HMCN1 LTBP1	7.53e-06	191	63	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 HMCN1 TLL1 SAMD5 LTBP1	7.72e-06	192	63	5	c157981b9a179925edcaabc0cb3b8805f0929004
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 HMCN1 SAMD5 NCAM1 LTBP1	7.72e-06	192	63	5	cd4c9b9ab17a779c154264f7459020f51e528ba5
ToppCell	droplet-Liver-HEPATOCYTES-1m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 UMODL1 PLCG2 PREX1	6.72e-05	154	63	4	66c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCell	droplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA6D KIAA0513 UMODL1 PREX1	7.24e-05	157	63	4	b527e88382c8d21188a0f222b3302523e8816dfc
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 ZFHX4 TRAPPC3L TLL1	7.79e-05	160	63	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMCN1 ZFHX4 TRAPPC3L TLL1	7.79e-05	160	63	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR1 TTLL3 ZNF451 GTF2IRD2	8.37e-05	163	63	4	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZFHX4 PIK3R2 CEP295 SPINK5	8.98e-05	166	63	4	9fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCell	343B-Lymphocytic-ILC\|343B / Donor, Lineage, Cell class and subclass (all cells)	TTLL3 MYO7A CEP295 PHF8	8.98e-05	166	63	4	a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMCN1 TLL1 SAMD5 LTBP1	9.63e-05	169	63	4	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HMCN1 TLL1 SAMD5 LTBP1	9.63e-05	169	63	4	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 TLL1 SAMD5 NCAM1	1.03e-04	172	63	4	fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 TLL1 SAMD5 NCAM1	1.03e-04	172	63	4	745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TLL1 SAMD5 NCAM1 LTBP1	1.10e-04	175	63	4	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TLL1 SAMD5 NCAM1 LTBP1	1.10e-04	175	63	4	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRJ UMODL1 SAMD5 PLCG2	1.13e-04	176	63	4	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 HMCN1 TLL1 SAMD5	1.18e-04	178	63	4	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.18e-04	178	63	4	ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 HMCN1 TLL1 SAMD5	1.18e-04	178	63	4	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.18e-04	178	63	4	87b04753650e45f12299c8456fb980d6c0d5961c
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.18e-04	178	63	4	ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRIM1 TRAPPC3L TLL1 SAMD5	1.23e-04	180	63	4	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C SEMA6D CRIM1 SAMD5	1.25e-04	181	63	4	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.25e-04	181	63	4	72c28baf4fd417ff4a7068603830d55074960144
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.25e-04	181	63	4	2ac4d3e8987d5a009d7908d8787e18165826202a
ToppCell	facs-Lung-3m-Endothelial-venous_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.25e-04	181	63	4	2628c7ac345eaaeecf8e34617e81948925962cb9
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 HMCN1 TLL1 SAMD5	1.31e-04	183	63	4	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	CACNA1C MITF NCAM1 LTBP1	1.34e-04	184	63	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	CRIM1 SAMD5 LTBP1 MBD4	1.34e-04	184	63	4	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	HMCN1 ZFHX4 TLL1 ZFP1	1.34e-04	184	63	4	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	SEMA6D TLL1 TUT7 LTBP1	1.36e-04	185	63	4	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CRIM1 HMCN1 PTPRJ SAMD5	1.39e-04	186	63	4	153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HMCN1 PTPRJ TLL1 LTBP1	1.39e-04	186	63	4	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CLSTN3 HMCN1 TLL1 LTBP1	1.39e-04	186	63	4	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CABP1 CACNA1C CRIM1 LTBP1	1.39e-04	186	63	4	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 HMCN1 TLL1 SAMD5	1.39e-04	186	63	4	41f1674afc17661eccaa779cdeb663db5e45685d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	UBR1 HMCN1 SMCHD1 CEP295	1.39e-04	186	63	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 HMCN1 TLL1 SAMD5	1.39e-04	186	63	4	aa006650cf21a2c51dfe1091681f67fdad939107
ToppCell	droplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 HMCN1 TLL1 SAMD5	1.42e-04	187	63	4	64dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C SEMA6D NCAM1 LTBP1	1.42e-04	187	63	4	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	droplet-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRIM1 HMCN1 TLL1 SAMD5	1.42e-04	187	63	4	b535d5447bf15e95dcf025a0a455628b956fc857
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HMCN1 TLL1 SAMD5 LTBP1	1.45e-04	188	63	4	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	Endothelial-Endothelial-E\|Endothelial / shred on cell class and cell subclass (v4)	CRIM1 SAMD5 LTBP1 MBD4	1.45e-04	188	63	4	2777eb7689b271c199021fe7d9db88ccebff14de
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C SEMA6D CRIM1 SAMD5	1.45e-04	188	63	4	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6D HMCN1 SAMD5 MITF	1.48e-04	189	63	4	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	343B-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTLL3 MYO7A CEP295 PHF8	1.48e-04	189	63	4	c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA6D HMCN1 SAMD5 MITF	1.48e-04	189	63	4	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C SEMA6D CRIM1 SAMD5	1.51e-04	190	63	4	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CABP1 CACNA1C CRIM1 HMCN1	1.51e-04	190	63	4	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C SEMA6D CRIM1 SAMD5	1.51e-04	190	63	4	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 TLL1 SAMD5 LTBP1	1.54e-04	191	63	4	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.57e-04	192	63	4	452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.57e-04	192	63	4	7ddaca206599603d4d0b2afb73ed2850225d277d
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C HMCN1 ZFHX4 LTBP1	1.57e-04	192	63	4	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C SEMA6D NCAM1 LTBP1	1.57e-04	192	63	4	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	droplet-Lung-30m-Endothelial-venous_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRIM1 HMCN1 TLL1 SAMD5	1.57e-04	192	63	4	bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ToppCell	COVID-19-kidney-Myeloid\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPRJ SMCHD1 PREX1 HSP90AA1	1.57e-04	192	63	4	0b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	CACNA1C CRIM1 HMCN1 SAMD5	1.60e-04	193	63	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CRIM1 PTPRJ TLL1 SAMD5	1.60e-04	193	63	4	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CRIM1 HMCN1 SAMD5 LTBP1	1.60e-04	193	63	4	58c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CACNA1C SEMA6D CRIM1 LTBP1	1.60e-04	193	63	4	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C HMCN1 SAMD5 LTBP1	1.60e-04	193	63	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CACNA1C MITF NCAM1 LTBP1	1.64e-04	194	63	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	CACNA1C MITF NCAM1 LTBP1	1.64e-04	194	63	4	c3535f7cc0076653c72db582047cff053c322397
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D HMCN1 ZFHX4 NCAM1	1.64e-04	194	63	4	d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D HMCN1 ZFHX4 NCAM1	1.64e-04	194	63	4	bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D HMCN1 ZFHX4 NCAM1	1.64e-04	194	63	4	408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C SMCHD1 TLL1 PLCG2	1.67e-04	195	63	4	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	droplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6D CRIM1 HMCN1 SAMD5	1.67e-04	195	63	4	0c15be3e7c238e329505dcbbe197a977d1019d45
ToppCell	droplet-Lung-18m-Endothelial-venous_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6D CRIM1 HMCN1 SAMD5	1.67e-04	195	63	4	45ac0fdbeb0982d798c613a6d15715d725608aa9
ToppCell	droplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA6D CRIM1 HMCN1 SAMD5	1.67e-04	195	63	4	5b1f04a745467876b09113ee17ababd3fcf9fb01
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CLSTN3 HMCN1 TLL1 SPINK5	1.67e-04	195	63	4	cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	CACNA1C CRIM1 HMCN1 LTBP1	1.67e-04	195	63	4	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C HMCN1 SAMD5 MITF	1.70e-04	196	63	4	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	SEMA6D RCN2 NCAM1 LTBP1	1.70e-04	196	63	4	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEO1 SEMA6D NCAM1 PREX1	1.70e-04	196	63	4	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C HMCN1 SAMD5 MITF	1.70e-04	196	63	4	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF384 SMCHD1 PREX1 NME8	1.74e-04	197	63	4	52246d1354c4e2b13d48c878643edf843d2b50d2
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CLSTN3 HMCN1 TLL1 SPINK5	1.80e-04	199	63	4	70e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	CACNA1C HMCN1 SAMD5 LTBP1	1.80e-04	199	63	4	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	UBR1 SEMA6D ZFHX4 CAMSAP2	1.80e-04	199	63	4	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HMCN1 UMODL1 PLCG2 PREX1	1.80e-04	199	63	4	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C SEMA6D CRIM1 SAMD5	1.80e-04	199	63	4	929f809579368201331d9099d8904b6e3c41797b
ToppCell	Bronchial-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C SEMA6D CRIM1 SAMD5	1.80e-04	199	63	4	854628ce91068093c14bd4d45ba38c41469f3549
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	SEMA6D RCN2 PREX1 SPINK5	1.84e-04	200	63	4	3d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	CLSTN3 HMCN1 TLL1 LTBP1	1.84e-04	200	63	4	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C HMCN1 SAMD5 LTBP1	1.84e-04	200	63	4	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUL4B KIAA0513 ZNF451	3.62e-04	98	63	3	95162072f3afc95e46f29db3d79ebd930bc09726
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Htr2c_(Lateral_habenula)\|Thalamus / BrainAtlas - Mouse McCarroll V32	UMODL1 TLL1 PHF8	3.73e-04	99	63	3	3dd31ed90bd1655cad954045afaef50de889008b
Drug	CHEMBL459685	PIK3R2 PLCG2 HSP90AA1 HSP90AA2P	5.16e-06	42	62	4	CID010995375
Drug	2qfo	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID000600769
Drug	3-amino-5-chlorobenzoic acid	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID010986726
Drug	3eko	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID011160307
Drug	monocillin III	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID006478910
Drug	pochonin A	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID006478909
Drug	1uyi	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID005289232
Drug	PU-H71	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID009549213
Drug	NSC683666	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID005469153
Drug	H 64	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID006914564
Drug	SureCN4151355	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID015942101
Drug	1uyc	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID000448969
Drug	PU-9	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID000448971
Drug	P u 0	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID000448974
Drug	2qf6	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID013373715
Drug	CHEBI:42139	HSP90AA1 HSP90AA2P	7.30e-06	2	62	2	CID011562562
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A	NEO1 CRIM1 MITF LTBP1 PLCG2 MGA	1.42e-05	193	62	6	6215_DN
Drug	deguelin	PIK3R2 PLCG2 HSP90AA1 HSP90AA2P	1.53e-05	55	62	4	CID000107935
Drug	pochonin D	HSP90AA1 HSP90AA2P	2.18e-05	3	62	2	CID006478913
Drug	azaquinone	HSP90AA1 HSP90AA2P	2.18e-05	3	62	2	CID000099132
Drug	d 1 v	HSP90AA1 HSP90AA2P	2.18e-05	3	62	2	CID000683940
Drug	HM-9	HSP90AA1 HSP90AA2P	2.18e-05	3	62	2	CID000433437
Drug	Glyoxylspermidine	HSP90AA1 HSP90AA2P	2.18e-05	3	62	2	CID000133564
Drug	AC1MD0RC	HSP90AA1 HSP90AA2P	2.18e-05	3	62	2	CID002829073
Drug	UCS15A	PLCG2 HSP90AA1 HSP90AA2P	2.47e-05	21	62	3	CID005311041
Drug	uranyl chloride	HSP90AA1 HSP90AA2P	4.36e-05	4	62	2	CID000082259
Drug	methoxyhydroquinone	HSP90AA1 HSP90AA2P	4.36e-05	4	62	2	CID000069988
Drug	11p110	HSP90AA1 HSP90AA2P	4.36e-05	4	62	2	CID002382787
Drug	5 _g	GTF2IRD2B LMAN1 ZNF451 GTF2IRD2	5.24e-05	75	62	4	CID002763225
Drug	1uy7	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID005289227
Drug	1uyd	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID000448970
Drug	Org 31806	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID000164147
Drug	CRT0044876	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID000081409
Drug	HCV-796	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID011561383
Drug	chaetochromin	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID000053277
Drug	1,1-diphenyl-2-propyn-1-ol	HSP90AA1 HSP90AA2P	7.26e-05	5	62	2	CID000092976
Drug	AC1L1CV3	PIK3R2 PLCG2 EIF2AK3 HSP90AA1 HSP90AA2P	9.76e-05	169	62	5	CID000002076
Drug	Hantzsch ester	HSP90AA1 HSP90AA2P	1.09e-04	6	62	2	CID000070849
Drug	3-aminocoumarin	HSP90AA1 HSP90AA2P	1.09e-04	6	62	2	CID000074217
Drug	Pu x	HSP90AA1 HSP90AA2P	1.09e-04	6	62	2	CID000448976
Drug	1ga8	GTF2IRD2B SEMA6D GTF2IRD2 SPG11 ARID1A	1.45e-04	184	62	5	CID000445801
Drug	17-aminogeldanamycin	HSP90AA1 HSP90AA2P	1.52e-04	7	62	2	CID000429444
Drug	Nepl	HSP90AA1 HSP90AA2P	1.52e-04	7	62	2	CID006439214
Drug	NSC330499	HSP90AA1 HSP90AA2P	1.52e-04	7	62	2	CID000433447
Drug	1,2,4,7,8-pentachlorodibenzo-p-dioxin	HSP90AA1 HSP90AA2P	1.52e-04	7	62	2	CID000042836
Drug	Zlll-mca	HSP90AA1 HSP90AA2P	1.52e-04	7	62	2	CID000132936
Drug	dienochlor	HSP90AA1 HSP90AA2P	1.52e-04	7	62	2	CID000016686
Drug	Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A	SMCHD1 MITF MFN2 LTBP1 CAMSAP2	1.91e-04	195	62	5	6234_DN
Drug	Naphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; PC3; HG-U133A	CUL4B ZNF384 ZFHX4 PIK3R2 MBD4	1.91e-04	195	62	5	1886_DN
Drug	estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A	CACNA1C SEMA6D ZFHX4 NCAM1 SPINK5	2.00e-04	197	62	5	5905_DN
Drug	Suprofen [40828-46-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	ZNF384 PLCG2 PHF8 ARID1A ZMYM6	2.00e-04	197	62	5	3343_DN
Drug	Ritodrine hydrochloride [23239-51-2]; Down 200; 12.4uM; MCF7; HT_HG-U133A	CRIM1 SUPT4H1 PRKCSH MBD4 SPINK5	2.00e-04	197	62	5	2635_DN
Drug	Cortisone [53-06-5]; Down 200; 11uM; MCF7; HT_HG-U133A	CUL4B CRIM1 SMCHD1 LTBP1 PLCG2	2.00e-04	197	62	5	7458_DN
Drug	chaetocin	EHMT2 MITF	2.02e-04	8	62	2	ctd:C002511
Drug	phenyldichloroarsine	HSP90AA1 HSP90AA2P	2.02e-04	8	62	2	CID000012762
Drug	GGMP	HSP90AA1 HSP90AA2P	2.02e-04	8	62	2	CID006443839
Drug	D-box	HSP90AA1 HSP90AA2P	2.02e-04	8	62	2	CID000133881
Drug	9-phenanthrol	HSP90AA1 HSP90AA2P	2.02e-04	8	62	2	CID000010229
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A	CUL4B LMAN1 CRIM1 ARID1A SPINK5	2.14e-04	200	62	5	3904_DN
Drug	Zlllal	CUL4B NEO1 PIK3R2 MITF MBD4 EIF2AK3 HSP90AA1 HSP90AA2P	2.48e-04	613	62	8	CID000107707
Drug	1yej	PTPRJ MITF EIF2AK3	2.51e-04	45	62	3	CID000449245
Drug	5,8-quinolinedione	HSP90AA1 HSP90AA2P	2.59e-04	9	62	2	CID000388306
Drug	antheridiol	HSP90AA1 HSP90AA2P	2.59e-04	9	62	2	CID000159927
Drug	JJ3	HSP90AA1 HSP90AA2P	2.59e-04	9	62	2	CID009927355
Drug	boceprevir	HSP90AA1 HSP90AA2P	2.59e-04	9	62	2	CID010324367
Drug	nibentan	HSP90AA1 HSP90AA2P	2.59e-04	9	62	2	CID000177905
Drug	noviose	HSP90AA1 HSP90AA2P	2.59e-04	9	62	2	CID005461025
Drug	n-C6	HSP90AA1 HSP90AA2P	3.24e-04	10	62	2	CID006420120
Drug	PU-6	HSP90AA1 HSP90AA2P	3.24e-04	10	62	2	CID000448968
Drug	formetanate	HSP90AA1 HSP90AA2P	3.24e-04	10	62	2	CID000031099
Drug	AC1L44ZM	HSP90AA1 HSP90AA2P	3.24e-04	10	62	2	CID000200744
Drug	AC1L194G	HSP90AA1 HSP90AA2P SPINK5	3.24e-04	49	62	3	CID000000386
Drug	MolPort-016-580-972	PIK3R2 HSP90AA1 HSP90AA2P	3.65e-04	51	62	3	CID009938589
Drug	PKR inhibitor	EIF2AK3 HSP90AA1 HSP90AA2P	3.86e-04	52	62	3	CID006490494
Drug	Pu-3	HSP90AA1 HSP90AA2P	3.95e-04	11	62	2	CID000448965
Drug	AC1L9ICX	HSP90AA1 HSP90AA2P	3.95e-04	11	62	2	CID000445664
Drug	I-hu	HSP90AA1 HSP90AA2P	3.95e-04	11	62	2	CID009547901
Drug	VER-49009	HSP90AA1 HSP90AA2P	3.95e-04	11	62	2	CID005327095
Drug	2ohu	HSP90AA1 HSP90AA2P	4.73e-04	12	62	2	CID011633167
Drug	4-oxo-2-nonenal	HSP90AA1 HSP90AA2P	4.73e-04	12	62	2	CID006445537
Drug	ptaquiloside	CACNA1C NEO1 MITF NCAM1	4.78e-04	133	62	4	ctd:C043680
Disease	pulmonary fibrosis (biomarker_via_orthology)	HSP90AB4P MFN2 HSP90AB3P	1.54e-04	50	61	3	DOID:3770 (biomarker_via_orthology)
Disease	cancer (implicated_via_orthology)	HSP90AB4P ARID1A HSP90AA1 HSP90AA2P HSP90AB3P	2.34e-04	268	61	5	DOID:162 (implicated_via_orthology)
Disease	QRS duration	CRIM1 HMCN1 PTPRJ MITF NCAM1	3.81e-04	298	61	5	EFO_0005055
Disease	T-Cell Lymphoma	ARID1A MGA	4.95e-04	16	61	2	C0079772
Disease	response to selective serotonin reuptake inhibitor	SEMA6D PREX1 EXOC4	6.63e-04	82	61	3	EFO_0005658
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	ARID1A HSP90AA1	7.03e-04	19	61	2	DOID:4928 (is_marker_for)
Disease	health study participation	CABP1 SUPT4H1 PIK3R2 EXOC4	7.19e-04	195	61	4	EFO_0010130
Disease	schizophrenia, intelligence, self reported educational attainment	CACNA1C SEMA6D HAT1 NCAM1 EXOC4	7.48e-04	346	61	5	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	blood pressure	PREX1 EXOC4	9.46e-04	22	61	2	EFO_0004325
Disease	alcohol use disorder measurement, alcohol consumption measurement	CACNA1C SEMA6D PTPRJ	1.08e-03	97	61	3	EFO_0007878, EFO_0009458
Disease	body weight	CACNA1C SEMA6D CRIM1 PTPRJ SMCHD1 TLL1 LTBP1 MGA EIF2AK3	1.08e-03	1261	61	9	EFO_0004338
Disease	smoking status measurement, Cannabis use, schizophrenia	SEMA6D NCAM1	1.65e-03	29	61	2	EFO_0006527, EFO_0007585, MONDO_0005090
Disease	muscular atrophy (biomarker_via_orthology)	HSP90AB4P HSP90AB3P	1.65e-03	29	61	2	DOID:767 (biomarker_via_orthology)
Disease	factor XI measurement, venous thromboembolism	PTPRJ PLCG2	1.76e-03	30	61	2	EFO_0004286, EFO_0004694

Protein segments in the cluster

Peptide	Gene	Start	Entry
GDTFIQDYDECERKE	UMODL1	891	Q5DID0
FFDSDFEEGKKCETN	CFAP97	16	Q9P2B7
YDCGKKRAADDAEVE	CLSTN3	221	Q9BQT9
VVFEAKNKVDDCNYA	EIF2AK3	606	Q9NZJ5
DFQFCGNKKLDEGEE	ADAM7	401	Q9H2U9
LFDLDNKDGEVYCID	EHMT2	1086	Q96KQ7
EFDKDKDGYINCRDL	CABP1	236	Q9NZU7
YFIQDGNEDEDKKAC	ATP1B4	206	Q9UN42
EKDRFVNDYDKDNDG	RCN2	231	Q14257
EDLDQEEKAKFGEYC	KIAA0513	111	O60268
YEKEEEQDQGVSCNK	ARID1A	2031	O14497
DSNCGFAEEYEDLKL	PTPRJ	1036	Q12913
AFCSDKLDEYLENEG	MGA	821	Q8IWI9
EKDFCKEYEKQVRNG	SPINK5	221	Q9NQ38
IPFDQVNDDYCDCKD	PRKCSH	46	P14314
DEYCVQQLKEFDGKS	HSP90AB3P	391	Q58FF7
DEYCVQQLKEFDGKS	HSP90AB4P	426	Q58FF6
NYKDADECLLFGQEI	LTBP1	1421	Q14766
TPDKNDYEFCAKVEN	LMAN1	221	P49257
EVEICGAEYDNNKFK	PLCG2	1086	P16885
DDDACKKAQQTGAFY	NUDT13	36	Q86X67
YDLNCDKLCADFQED	MFN2	526	O95140
DKGTYICEAENQFGK	HMCN1	861	Q96RW7
NCEEDDIAGYDKSKN	PPP4R3C	486	Q6ZMV5
FEEQGQTQEKCSKEY	PIK3R2	491	O00459
ENEKGRLEEAYEKCD	EXOC4	41	Q96A65
YASKVDENFDCVEAD	HAT1	91	O14929
EQGEQEYKNCELDKN	CACNA1C	1191	Q13936
DVNADGKFDYIKFCK	EFCAB7	151	A8K855
NYCKNDEGDIFLAAE	CRIM1	751	Q9NZV1
FCSAKDSEHNEKYED	MBD4	336	O95243
DEYCVQQLKEFEGKT	HSP90AA1	526	P07900
DFQKDFAKYCVAEGL	GTF2IRD2	71	Q86UP8
DFQKDFAKYCVAEGL	GTF2IRD2B	71	Q6EKJ0
ENVCGDDYDEAVKLK	CEP295	1906	Q9C0D2
GESDKEQFDDDQKVC	CAMSAP2	1146	Q08AD1
DIEDGDKFICNDDFK	CUL4B	801	Q13620
DDITNEEYGEFCKNL	HSP90AA2P	301	Q14568
IKDNDKEDGCFYFRD	SMCHD1	1436	A6NHR9
GFAANFFKEEDECAK	TLL1	566	O43897
SFVDNGYDDLEVCKQ	SAMD5	21	Q5TGI4
VKSDEGFYQCIAEND	NEO1	401	Q92859
QEEDYGFDIEEKNKA	PREX1	631	Q8TCU6
LVKTIDQFEYDGCDN	SUPT4H1	21	P63272
DEAEYICIAENKAGE	NCAM1	281	P13591
DSFLKYDCKDEFNKQ	SPG11	831	Q96JI7
YAGKQTDECNEFGKA	ZFP1	126	Q6P2D0
QDEHDNEIKIKYFCG	ZNF451	656	Q9Y4E5
QKKQCYKDEDDDAQD	ZFHX4	2286	Q86UP3
EDDDDHQKDGKTYRC	ZNF384	216	Q8TF68
GDCVYENLAFQKEED	TULP2	201	O00295
KEAQALCKEYENEDY	NME8	356	Q8N427
CEKEGFYKFEEQNRA	MITF	191	O75030
CKDYENDEDVNKQLD	TRAPPC3	31	O43617
DGENVGECKDQKEIY	ZNF682	116	O95780
VKAGAYAACQEAKED	UBR1	271	Q8IWV7
YCLGAEDDKKAFIED	TTLL3	131	Q9Y4R7
DKIKEEPDNAQEYGC	ZMYM6	21	O95789
DEQDSLGACFKDAEY	PHF8	836	Q9UPP1
CKDYEKDEDVNQYLD	TRAPPC3L	31	Q5T215
CIQADVNSDDYKGDK	TUT7	726	Q5VYS8
AYNHAKCSAENEEDK	SEMA6D	471	Q8NFY4
KFGEYRCEKEDDLAE	MYO7A	1376	Q13402