Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase activity	CERKL STK36 ATR STK26 MAPKAPK5 TRRAP EDNRA NUAK2 COQ8A AGK STK39 EIF2AK4 ATM PALS2 ADPGK ALPK2	2.81e-05	764	127	16	GO:0016301
GeneOntologyMolecularFunction	ceramide kinase activity	CERKL AGK	1.20e-04	3	127	2	GO:0001729
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	ATR ATM	1.20e-04	3	127	2	GO:0035979
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CERKL STK36 ATR STK26 MAPKAPK5 TRRAP EDNRA NUAK2 COQ8A AGK STK39 EIF2AK4 ATM PALS2 ADPGK ALPK2	3.04e-04	938	127	16	GO:0016772
GeneOntologyMolecularFunction	histone H2AX kinase activity	ATR ATM	3.96e-04	5	127	2	GO:0141003
GeneOntologyMolecularFunction	hypotaurine monooxygenase activity	FMO2 FMO4	3.96e-04	5	127	2	GO:0047822
GeneOntologyMolecularFunction	protein serine kinase activity	STK36 ATR STK26 MAPKAPK5 NUAK2 STK39 EIF2AK4 ATM ALPK2	5.30e-04	363	127	9	GO:0106310
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	STK36 ATR STK26 MAPKAPK5 EDNRA NUAK2 COQ8A AGK STK39 EIF2AK4 ATM ADPGK ALPK2	5.91e-04	709	127	13	GO:0016773
GeneOntologyMolecularFunction	N,N-dimethylaniline monooxygenase activity	FMO2 FMO4	5.92e-04	6	127	2	GO:0004499
GeneOntologyBiologicalProcess	telomerase catalytic core complex assembly	ATR ATM	3.47e-05	2	122	2	GO:1904868
GeneOntologyBiologicalProcess	positive regulation of telomerase catalytic core complex assembly	ATR ATM	3.47e-05	2	122	2	GO:1904884
GeneOntologyBiologicalProcess	regulation of telomerase catalytic core complex assembly	ATR ATM	3.47e-05	2	122	2	GO:1904882
GeneOntologyBiologicalProcess	positive regulation of canonical NF-kappaB signal transduction	MYD88 TLR6 PLEKHG5 TLR8 EDNRA DDX1 TLR4 CCR7	3.99e-05	213	122	8	GO:0043123
GeneOntologyBiologicalProcess	cellular response to oxidised low-density lipoprotein particle stimulus	MYD88 TLR6 TLR4	7.01e-05	14	122	3	GO:0140052
GeneOntologyBiologicalProcess	positive regulation of interleukin-1 beta production	MYD88 TLR6 TLR8 TLR4 CCR7	7.75e-05	74	122	5	GO:0032731
GeneOntologyBiologicalProcess	establishment of RNA localization to telomere	ATR ATM	1.04e-04	3	122	2	GO:0097694
GeneOntologyBiologicalProcess	establishment of protein-containing complex localization to telomere	ATR ATM	1.04e-04	3	122	2	GO:0097695
GeneOntologyBiologicalProcess	neutrophil migration	MYD88 GBF1 EDNRA PLA2G1B CCR7 VAV1	1.24e-04	130	122	6	GO:1990266
GeneOntologyBiologicalProcess	positive regulation of interleukin-1 production	MYD88 TLR6 TLR8 TLR4 CCR7	1.77e-04	88	122	5	GO:0032732
GeneOntologyBiologicalProcess	regulation of inflammasome-mediated signaling pathway	MYD88 TLR6 PYDC5 TLR4	1.85e-04	48	122	4	GO:0141085
GeneOntologyBiologicalProcess	substrate localization to autophagosome	STBD1 SMURF1	2.07e-04	4	122	2	GO:0061753
GeneOntologyCellularComponent	vesicle membrane	MYD88 STBD1 RAB17 ATR MYO6 ABCA13 STK26 ANXA11 SYT6 TLR6 TLR8 NCDN SNX13 ITPR1 SLC32A1 SEC24D CLCN6 SEC24B TLR4 ATM	9.07e-05	1325	123	20	GO:0012506
Domain	FAT	ATR TRRAP ATM	5.77e-06	6	125	3	PS51189
Domain	FATC	ATR TRRAP ATM	5.77e-06	6	125	3	PS51190
Domain	FAT	ATR TRRAP ATM	5.77e-06	6	125	3	PF02259
Domain	PIK-rel_kinase_FAT	ATR TRRAP ATM	5.77e-06	6	125	3	IPR003151
Domain	FATC_dom	ATR TRRAP ATM	5.77e-06	6	125	3	IPR003152
Domain	PIK_FAT	ATR TRRAP ATM	5.77e-06	6	125	3	IPR014009
Domain	FATC	ATR TRRAP ATM	5.77e-06	6	125	3	SM01343
Domain	TIR	MYD88 TLR6 TLR8 TLR4	1.05e-05	21	125	4	SM00255
Domain	TIR	MYD88 TLR6 TLR8 TLR4	1.27e-05	22	125	4	PF01582
Domain	-	MYD88 TLR6 TLR8 TLR4	1.53e-05	23	125	4	3.40.50.10140
Domain	ARM-type_fold	STK36 GBF1 ATR TRRAP NCDN PPP4R4 ITPR1 RANBP17 UPF2 IPO13 ATM	1.76e-05	339	125	11	IPR016024
Domain	TIR	MYD88 TLR6 TLR8 TLR4	1.83e-05	24	125	4	PS50104
Domain	TIR_dom	MYD88 TLR6 TLR8 TLR4	2.17e-05	25	125	4	IPR000157
Domain	DH_1	PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	6.38e-05	63	125	5	PS00741
Domain	RhoGEF	PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	9.22e-05	68	125	5	SM00325
Domain	TUDOR	TDRD9 RNF17 TDRD12	1.01e-04	14	125	3	PF00567
Domain	RhoGEF	PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	1.06e-04	70	125	5	PF00621
Domain	DH_2	PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	1.06e-04	70	125	5	PS50010
Domain	-	PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	1.13e-04	71	125	5	1.20.900.10
Domain	DH-domain	PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	1.13e-04	71	125	5	IPR000219
Domain	-	ATR TRRAP ATM	1.54e-04	16	125	3	1.10.1070.11
Domain	PI3Kc	ATR TRRAP ATM	1.54e-04	16	125	3	SM00146
Domain	PI3_PI4_kinase	ATR TRRAP ATM	2.22e-04	18	125	3	PF00454
Domain	PI3_4_KINASE_1	ATR TRRAP ATM	2.22e-04	18	125	3	PS00915
Domain	PI3_4_KINASE_2	ATR TRRAP ATM	2.22e-04	18	125	3	PS00916
Domain	PI3/4_kinase_cat_dom	ATR TRRAP ATM	2.22e-04	18	125	3	IPR000403
Domain	PI3_4_KINASE_3	ATR TRRAP ATM	2.22e-04	18	125	3	PS50290
Domain	Flavin_mOase	FMO2 FMO4	4.39e-04	5	125	2	IPR000960
Domain	Toll-like_receptor	TLR6 TLR4	4.39e-04	5	125	2	IPR017241
Domain	DiMe-aniline_mOase	FMO2 FMO4	4.39e-04	5	125	2	IPR012143
Domain	FMO-like	FMO2 FMO4	4.39e-04	5	125	2	PF00743
Domain	FATC	ATR ATM	4.39e-04	5	125	2	PF02260
Domain	Flavin_mOase-like	FMO2 FMO4	4.39e-04	5	125	2	IPR020946
Domain	TUDOR	TDRD9 RNF17 TDRD12	4.70e-04	23	125	3	PS50304
Domain	P-loop_NTPase	TPST1 RAB17 TDRD9 MYO6 ABCA13 SLFN14 DNAH14 DDX1 NLRP14 TRANK1 DNAH12 KIF15 RECQL5 PALS2 TDRD12	5.47e-04	848	125	15	IPR027417
Domain	HEAT	STK36 ATR PPP4R1L IPO13	6.14e-04	58	125	4	IPR000357
Domain	Sec23/24_helical_dom	SEC24D SEC24B	6.55e-04	6	125	2	IPR006900
Domain	Sec23_24_beta_S	SEC24D SEC24B	6.55e-04	6	125	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24D SEC24B	6.55e-04	6	125	2	PF04810
Domain	Sec23_trunk	SEC24D SEC24B	6.55e-04	6	125	2	PF04811
Domain	Sec23_helical	SEC24D SEC24B	6.55e-04	6	125	2	PF04815
Domain	Sec23_BS	SEC24D SEC24B	6.55e-04	6	125	2	PF08033
Domain	Sec23/24_trunk_dom	SEC24D SEC24B	6.55e-04	6	125	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24D SEC24B	6.55e-04	6	125	2	IPR006895
Domain	Tudor	TDRD9 RNF17 TDRD12	1.04e-03	30	125	3	IPR002999
Domain	Kinase-like_dom	STK36 ATR STK26 MAPKAPK5 TRRAP NUAK2 COQ8A STK39 EIF2AK4 ATM ALPK2	1.04e-03	542	125	11	IPR011009
Domain	HEAT_REPEAT	ATR PPP4R1L PPP4R4 IPO13	1.25e-03	70	125	4	PS50077
Domain	DEAD/DEAH_box_helicase_dom	TDRD9 DDX1 RECQL5 TDRD12	1.46e-03	73	125	4	IPR011545
Domain	DEAD	TDRD9 DDX1 RECQL5 TDRD12	1.46e-03	73	125	4	PF00270
Domain	-	TPST1 RAB17 TDRD9 ABCA13 SLFN14 DNAH14 DDX1 NLRP14 TRANK1 DNAH12 RECQL5 PALS2 TDRD12	1.48e-03	746	125	13	3.40.50.300
Domain	GDS_CDC24_CS	PREX2 ARHGEF10 VAV1	2.24e-03	39	125	3	IPR001331
Domain	ARM-like	STK36 ATR PPP4R1L TRRAP PPP4R4 RANBP17 IPO13	2.29e-03	270	125	7	IPR011989
Domain	aa-tRNA-synt_IIb	PARS2 EIF2AK4	2.35e-03	11	125	2	IPR002314
Domain	-	PARS2 EIF2AK4	2.35e-03	11	125	2	3.40.50.800
Domain	tRNA-synt_2b	PARS2 EIF2AK4	2.35e-03	11	125	2	PF00587
Domain	-	STK36 ATR TRRAP PPP4R4 RANBP17 IPO13	3.83e-03	222	125	6	1.25.10.10
Domain	Gelsolin	SEC24D SEC24B	3.84e-03	14	125	2	PF00626
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DNAH12	3.84e-03	14	125	2	IPR024317
Domain	Gelsolin-like_dom	SEC24D SEC24B	3.84e-03	14	125	2	IPR007123
Domain	Anticodon-bd	PARS2 EIF2AK4	3.84e-03	14	125	2	IPR004154
Domain	AAA_8	DNAH14 DNAH12	3.84e-03	14	125	2	PF12780
Domain	HEAT	STK36 ATR PPP4R1L	4.06e-03	48	125	3	PF02985
Domain	DHC_fam	DNAH14 DNAH12	4.41e-03	15	125	2	IPR026983
Domain	Diacylglycerol_kinase_cat_dom	CERKL AGK	4.41e-03	15	125	2	IPR001206
Domain	DAGK	CERKL AGK	4.41e-03	15	125	2	PS50146
Domain	Dynein_heavy	DNAH14 DNAH12	4.41e-03	15	125	2	PF03028
Domain	PI3/4_kinase_CS	ATR ATM	4.41e-03	15	125	2	IPR018936
Domain	IBN_N	RANBP17 IPO13	4.41e-03	15	125	2	PF03810
Domain	DAGK_cat	CERKL AGK	4.41e-03	15	125	2	PF00781
Domain	Dynein_heavy_dom	DNAH14 DNAH12	4.41e-03	15	125	2	IPR004273
Domain	IBN_N	RANBP17 IPO13	5.01e-03	16	125	2	SM00913
Domain	NAD/diacylglycerol_kinase	CERKL AGK	5.66e-03	17	125	2	IPR016064
Domain	Importin-beta_N	RANBP17 IPO13	5.66e-03	17	125	2	IPR001494
Domain	HEAT_type_2	ATR PPP4R4	5.66e-03	17	125	2	IPR021133
Domain	LRR_6	NLRP14 TLR4 LUM	5.96e-03	55	125	3	PF13516
Domain	aa-tRNA-synth_II	PARS2 EIF2AK4	6.34e-03	18	125	2	IPR006195
Domain	AA_TRNA_LIGASE_II	PARS2 EIF2AK4	6.34e-03	18	125	2	PS50862
Pathway	WP_MYD88_DISTINCT_INPUTOUTPUT_PATHWAY	MYD88 TLR6 TLR8 TLR4	3.88e-06	18	87	4	M39478
Pathway	WP_TOLLLIKE_RECEPTOR_SIGNALING_RELATED_TO_MYD88	MYD88 TLR6 TLR8 TLR4	3.75e-05	31	87	4	M39573
Pathway	REACTOME_IRAK4_DEFICIENCY_TLR2_4	MYD88 TLR6 TLR4	1.73e-04	18	87	3	M27464
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	MYD88 PLEKHG5 ARHGEF10L ARHGEF10 VAV1	1.77e-04	85	87	5	MM14746
Pathway	REACTOME_RHOA_GTPASE_CYCLE	STBD1 PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	2.43e-04	142	87	6	MM15576
Pathway	REACTOME_DEATH_RECEPTOR_SIGNALING	MYD88 PLEKHG5 ARHGEF10L USP21 ARHGEF10 VAV1	2.43e-04	142	87	6	MM15431
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	PLEKHG5 ARHGEF10L ARHGEF10 VAV1	2.92e-04	52	87	4	MM14743
Pathway	REACTOME_RHOA_GTPASE_CYCLE	STBD1 PLEKHG5 PREX2 ARHGEF10L ARHGEF10 VAV1	3.15e-04	149	87	6	M41805
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	MYD88 PLEKHG5 ARHGEF10L ARHGEF10 VAV1	3.29e-04	97	87	5	M9400
Pathway	WP_CATALYTIC_CYCLE_OF_MAMMALIAN_FLAVINCONTAINING_MONOOXYGENASES_FMOS	FMO2 FMO4	3.72e-04	5	87	2	M39449
Pathway	REACTOME_DEATH_RECEPTOR_SIGNALING	MYD88 PLEKHG5 ARHGEF10L USP21 ARHGEF10 VAV1	3.76e-04	154	87	6	M27697
Pathway	PID_TOLL_ENDOGENOUS_PATHWAY	MYD88 TLR6 TLR4	4.18e-04	24	87	3	M264
Pathway	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	PLEKHG5 ARHGEF10L ARHGEF10 VAV1	4.76e-04	59	87	4	M11215
Pathway	REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	MYD88 NPEPPS SMURF1 TLR6 GLMN SEC24D TRIM69 SEC24B TLR4	5.60e-04	381	87	9	M1066
Pubmed	Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.	MYD88 TLR6 TLR8 TLR4	1.17e-08	8	127	4	12724322
Pubmed	Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling.	MYD88 TLR6 TLR8 TLR4	1.65e-07	14	127	4	14625308
Pubmed	Mast cells as sensors of cell injury through IL-33 recognition.	MYD88 TLR6 TLR8 TLR4	1.65e-07	14	127	4	21239713
Pubmed	Toll-like receptor 2 (TLR2)-dependent-positive and TLR2-independent-negative regulation of proinflammatory cytokines by mycobacterial lipomannans.	MYD88 TLR6 TLR4	1.90e-07	4	127	3	15034058
Pubmed	Association of Toll-like receptor polymorphisms with HIV status in North Americans.	TLR6 TLR8 TLR4	1.90e-07	4	127	3	25253287
Pubmed	Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis.	MYD88 TLR6 TLR4	1.90e-07	4	127	3	18203139
Pubmed	Expression of Toll-like receptors in the developing brain.	MYD88 TLR6 TLR8 TLR4	2.98e-07	16	127	4	22666391
Pubmed	A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.	MYD88 TLR6 TLR8 TLR4	2.98e-07	16	127	4	16024789
Pubmed	Natural selection in the TLR-related genes in the course of primate evolution.	MYD88 TLR6 TLR8 TLR4	2.98e-07	16	127	4	18810425
Pubmed	Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity.	MYD88 TLR6 TLR4	4.73e-07	5	127	3	18559428
Pubmed	TLR-dependent control of Francisella tularensis infection and host inflammatory responses.	MYD88 TLR6 TLR4	4.73e-07	5	127	3	19936231
Pubmed	Regulation of B1 cell migration by signals through Toll-like receptors.	MYD88 TLR4 CCR7	4.73e-07	5	127	3	17060475
Pubmed	The role of TLR4 activation in photoreceptor mitochondrial oxidative stress.	MYD88 CASP7 TLR4	4.73e-07	5	127	3	21666244
Pubmed	Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.	ATR UPF2 ATM	4.73e-07	5	127	3	16086026
Pubmed	Cross talk between MyD88 and focal adhesion kinase pathways.	MYD88 TLR6 TLR4	4.73e-07	5	127	3	15905587
Pubmed	Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.	MYD88 TLR6 TLR4	4.73e-07	5	127	3	19019963
Pubmed	Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.	MYD88 TLR6 TLR4	9.43e-07	6	127	3	21685327
Pubmed	Contrasting roles of the IL-1 and IL-18 receptors in MyD88-dependent contact hypersensitivity.	MYD88 TLR6 TLR4	9.43e-07	6	127	3	19657352
Pubmed	Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.	MYD88 SMURF1 TLR4	9.43e-07	6	127	3	21897371
Pubmed	Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.	MYD88 TLR4 CCR7	9.43e-07	6	127	3	16413927
Pubmed	Toll-like receptor 2 expression on c-kit+ cells tracks the emergence of embryonic definitive hematopoietic progenitors.	MYD88 TLR6 TLR8 TLR4	1.18e-06	22	127	4	31729371
Pubmed	Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.	MYD88 TLR8 TLR4	1.65e-06	7	127	3	14976262
Pubmed	Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results.	MYD88 TLR6 TLR4	1.65e-06	7	127	3	18325643
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	GBF1 TRRAP ITPR1 CRACD COQ8A ATM	2.38e-06	104	127	6	31240132
Pubmed	Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming.	MYD88 TLR6 TLR4	3.93e-06	9	127	3	34559989
Pubmed	Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.	MYD88 TLR6 TLR4	3.93e-06	9	127	3	15128825
Pubmed	Regulation of angiogenesis, mural cell recruitment and adventitial macrophage behavior by Toll-like receptors.	TLR6 TLR8 TLR4	3.93e-06	9	127	3	24091496
Pubmed	Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.	MYD88 TLR6 TLR4	3.93e-06	9	127	3	19543401
Pubmed	Polymorphisms in innate immunity genes associated with development of bronchiolitis obliterans after lung transplantation.	TLR6 TLR8 TLR4	5.60e-06	10	127	3	20227302
Pubmed	Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.	MYD88 TLR6 TLR4	5.60e-06	10	127	3	19122641
Pubmed	A family of human receptors structurally related to Drosophila Toll.	TLR6 TLR8 TLR4	5.60e-06	10	127	3	9435236
Pubmed	Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain.	MYD88 TLR6 TLR4	5.60e-06	10	127	3	21098227
Pubmed	[Expression of toll-like receptors in human epidermal keratinocytes].	TLR6 TLR8 TLR4	5.60e-06	10	127	3	18686608
Pubmed	Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.	MYD88 TLR6 TLR4	5.60e-06	10	127	3	18180310
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	ATR TRRAP ATM	5.60e-06	10	127	3	18160036
Pubmed	Toll-like receptors.	TLR6 TLR8 TLR4	5.60e-06	10	127	3	11782555
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	ATR TRRAP ATM	7.68e-06	11	127	3	20427287
Pubmed	Toll-like receptors.	TLR6 TLR8 TLR4	7.68e-06	11	127	3	18394314
Pubmed	CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.	MYD88 TLR6 TLR4	7.68e-06	11	127	3	20037584
Pubmed	Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.	MYD88 TLR6 TLR4	7.68e-06	11	127	3	17572686
Pubmed	Pathogen recognition in the innate immune response.	MYD88 TLR6 TLR4	1.02e-05	12	127	3	19382893
Pubmed	TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.	MYD88 TLR6 TLR4	1.02e-05	12	127	3	26831104
Pubmed	Murine cerebral malaria development is independent of toll-like receptor signaling.	MYD88 TLR6 TLR4	1.02e-05	12	127	3	17456769
Pubmed	The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.	MYD88 TLR6 TLR4	1.02e-05	12	127	3	20495560
Pubmed	Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE.	MYD88 TLR6 TLR4	1.02e-05	12	127	3	19254290
Pubmed	Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks.	ATR ATM	1.32e-05	2	127	2	19285939
Pubmed	MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and secondary brain edema in a mouse model of intracerebral hemorrhage.	MYD88 TLR4	1.32e-05	2	127	2	36482445
Pubmed	IL-4-dependent Th2 collateral priming to inhaled antigens independent of Toll-like receptor 4 and myeloid differentiation factor 88.	MYD88 TLR4	1.32e-05	2	127	2	15034070
Pubmed	Expression variations of DNA damage response genes ATM and ATR in blood cancer patients.	ATR ATM	1.32e-05	2	127	2	37338595
Pubmed	Microglial activation by Citrobacter koseri is mediated by TLR4- and MyD88-dependent pathways.	MYD88 TLR4	1.32e-05	2	127	2	19812209
Pubmed	Ischemia-reperfusion lung injury is attenuated in MyD88-deficient mice.	MYD88 TLR4	1.32e-05	2	127	2	24146959
Pubmed	[Effect of yiqi huoxue recipe containing drug-serum on the Toll-Iike receptor-4 and its downstream signaling components MyD88 as well as the tumor necrosis factor receptor related factor-6 in human vein endothelial cells].	MYD88 TLR4	1.32e-05	2	127	2	20681284
Pubmed	DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.	ATR ATM	1.32e-05	2	127	2	28851706
Pubmed	Atorvastatin attenuates TLR4-mediated NF-kappaB activation in a MyD88-dependent pathway.	MYD88 TLR4	1.32e-05	2	127	2	19548630
Pubmed	Inhibitory Effects of the Lactobacillus rhamnosus GG Effector Protein HM0539 on Inflammatory Response Through the TLR4/MyD88/NF-кB Axis.	MYD88 TLR4	1.32e-05	2	127	2	33123130
Pubmed	Toll-like receptor 4 and myeloid differentiation factor 88 are required for gastric bypass-induced metabolic effects.	MYD88 TLR4	1.32e-05	2	127	2	34462225
Pubmed	Upregulated expression of toll-like receptor 4 in monocytes correlates with severity of acute cerebral infarction.	MYD88 TLR4	1.32e-05	2	127	2	18523439
Pubmed	Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM).	ATR ATM	1.32e-05	2	127	2	34151669
Pubmed	Toll-like receptor 4 prompts human breast cancer cells invasiveness via lipopolysaccharide stimulation and is overexpressed in patients with lymph node metastasis.	MYD88 TLR4	1.32e-05	2	127	2	25299052
Pubmed	Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88.	MYD88 TLR4	1.32e-05	2	127	2	32513051
Pubmed	TLR4 activation mediates kidney ischemia/reperfusion injury.	MYD88 TLR4	1.32e-05	2	127	2	17853945
Pubmed	Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.	TLR6 TLR4	1.32e-05	2	127	2	20200442
Pubmed	Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.	ATR ATM	1.32e-05	2	127	2	16213462
Pubmed	TLR4-MyD88 pathway promotes the imbalanced activation of NLRP3/NLRP6 via caspase-8 stimulation after alkali burn injury.	MYD88 TLR4	1.32e-05	2	127	2	30008389
Pubmed	The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.	MYD88 TLR4	1.32e-05	2	127	2	28238930
Pubmed	ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.	ATR ATM	1.32e-05	2	127	2	27442013
Pubmed	Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells.	ATR ATM	1.32e-05	2	127	2	24726882
Pubmed	Platycodin D inhibits MPP+-induced inflammatory response in BV-2 cells through the TLR4/MyD88/NF-κB signaling pathway.	MYD88 TLR4	1.32e-05	2	127	2	32429710
Pubmed	Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake.	MYD88 TLR4	1.32e-05	2	127	2	19461045
Pubmed	rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.	ATR ATM	1.32e-05	2	127	2	26061708
Pubmed	Cutting edge: FimH adhesin of type 1 fimbriae is a novel TLR4 ligand.	MYD88 TLR4	1.32e-05	2	127	2	18981086
Pubmed	Toll-like receptor 4-myeloid differentiation factor 88 signaling contributes to ventilator-induced lung injury in mice.	MYD88 TLR4	1.32e-05	2	127	2	20683250
Pubmed	The MyD88-independent pathway is not mobilized in human neutrophils stimulated via TLR4.	MYD88 TLR4	1.32e-05	2	127	2	17513785
Pubmed	Dioscin prevents LPS‑induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70.	MYD88 TLR4	1.32e-05	2	127	2	29512786
Pubmed	Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity.	MYD88 TLR4	1.32e-05	2	127	2	20381591
Pubmed	The protective effects of S14G-humanin (HNG) against lipopolysaccharide (LPS)- induced inflammatory response in human dental pulp cells (hDPCs) mediated by the TLR4/MyD88/NF-κB pathway.	MYD88 TLR4	1.32e-05	2	127	2	34605740
Pubmed	Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.	ATR ATM	1.32e-05	2	127	2	20103595
Pubmed	Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades.	MYD88 TLR4	1.32e-05	2	127	2	10607756
Pubmed	TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation.	MYD88 TLR4	1.32e-05	2	127	2	25313083
Pubmed	Interplay between ATM and ATR in the regulation of common fragile site stability.	ATR ATM	1.32e-05	2	127	2	17934520
Pubmed	High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals correlates with poor prognosis in colorectal cancer.	MYD88 TLR4	1.32e-05	2	127	2	20145615
Pubmed	Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.	ATR ATM	1.32e-05	2	127	2	25483091
Pubmed	ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.	ATR ATM	1.32e-05	2	127	2	23592994
Pubmed	Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.	ATR ATM	1.32e-05	2	127	2	19527713
Pubmed	The TLR4-MyD88 Signaling Axis Regulates Lung Monocyte Differentiation Pathways in Response to Streptococcus pneumoniae.	MYD88 TLR4	1.32e-05	2	127	2	33042124
Pubmed	Identification of Gut Bacteria such as Lactobacillus johnsonii that Disseminate to Systemic Tissues of Wild Type and MyD88-/- Mice.	MYD88 CCR7	1.32e-05	2	127	2	35023810
Pubmed	Glabridin attenuates atopic dermatitis progression through downregulating the TLR4/MyD88/NF-κB signaling pathway.	MYD88 TLR4	1.32e-05	2	127	2	34021857
Pubmed	Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers.	MYD88 TLR4	1.32e-05	2	127	2	22985132
Pubmed	SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway.	MYD88 TLR8	1.32e-05	2	127	2	33718825
Pubmed	Nuclear factor translocation and acute anterior uveitis.	MYD88 TLR4	1.32e-05	2	127	2	21264236
Pubmed	The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol.	MYD88 TLR4	1.32e-05	2	127	2	11500829
Pubmed	The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.	MYD88 TLR4	1.32e-05	2	127	2	18792393
Pubmed	The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer.	MYD88 TLR4	1.32e-05	2	127	2	24977712
Pubmed	Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis.	MYD88 TLR4	1.32e-05	2	127	2	15826931
Pubmed	Significant Association between Toll-Like Receptor Gene Polymorphisms and Posttransplantation Diabetes Mellitus.	TLR6 TLR4	1.32e-05	2	127	2	27486667
Pubmed	ATM and ATR signaling at a glance.	ATR ATM	1.32e-05	2	127	2	26567218
Pubmed	Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation.	MYD88 TLR4	1.32e-05	2	127	2	22760779
Pubmed	Is serum amyloid A an endogenous TLR4 agonist?	MYD88 TLR4	1.32e-05	2	127	2	18252871
Pubmed	TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer.	MYD88 TLR4	1.32e-05	2	127	2	19826413
Pubmed	Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways.	MYD88 TLR4	1.32e-05	2	127	2	16186163
GeneFamily	CD molecules\|Toll like receptors	TLR6 TLR8 TLR4	1.02e-05	10	81	3	948
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PREX2 ARHGEF10L ARHGEF10 VAV1	2.18e-04	66	81	4	722
GeneFamily	Tudor domain containing	TDRD9 RNF17 TDRD12	6.03e-04	37	81	3	780
GeneFamily	Dyneins, axonemal	DNAH14 DNAH12	2.58e-03	17	81	2	536
Coexpression	SOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_1DY_UP	MYD88 TLR6 TLR8 TLR4	2.77e-06	21	125	4	M41167
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	TPST1 GBF1 ATR NPEPPS TRRAP ZNF804A SNX13 ITPR1 SEC24D UPF2 ARHGEF10 ZNF451 SEC24B STK39 PALS2	1.46e-05	856	125	15	M4500
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500	ATR ZNF318 RNF17 ZNF518A ESCO2 RANBP17 DDIAS TRANK1 ATM EDRF1 TDRD12	1.52e-05	385	123	11	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 GLS2 ALDH1L1 CCKAR PAH RETREG1 PLA2G1B	7.95e-07	179	126	7	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYT6 GCNT2 ZNF804A PREX2 SLC32A1 CRACD LUM	1.23e-06	191	126	7	06760c3bb40e4f66879a5f5e09c9abfce4ebbba3
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ALDH1L1 PIGZ TLR8 DNAH14 DDIAS TGM3	6.61e-06	161	126	6	f5da03c426f3124ea302bd343b6bca81cafee858
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ALDH1L1 PIGZ TLR8 DNAH14 DDIAS TGM3	6.85e-06	162	126	6	4e3bf16799c6552366d4c7e42b1328a05dcad7e7
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CERKL STBD1 TIGD4 METTL24 TLR4	7.15e-06	94	126	5	d78535a7a0fda7299b01912333b944dc5e0a0361
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CERKL STBD1 TIGD4 METTL24 TLR4	7.15e-06	94	126	5	dfc3f7977b9df433009d1d2d465b64a2de5806e2
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 SYT6 KCTD4 PPP4R4 PADI1 SPINK5	8.72e-06	169	126	6	8c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 SYT6 KCTD4 PPP4R4 PADI1 SPINK5	8.72e-06	169	126	6	86041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 ABCA13 SLFN14 TRANK1 STK39 ADPGK	9.64e-06	172	126	6	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SGO1 EDNRA ESCO2 KIF15 MTBP TDRD12	9.96e-06	173	126	6	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SGO1 EDNRA ESCO2 KIF15 MTBP TDRD12	9.96e-06	173	126	6	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLXNA3 SGO1 PLEKHG5 ESCO2 DDIAS KIF15	1.03e-05	174	126	6	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLXNA3 SGO1 PLEKHG5 ESCO2 DDIAS KIF15	1.03e-05	174	126	6	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 ALDH1L1 CCKAR PAH RETREG1 PLA2G1B	1.06e-05	175	126	6	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 TDRD9 RNF17 EDNRA FAM124A LUM	1.17e-05	178	126	6	6d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 TDRD9 RNF17 EDNRA FAM124A LUM	1.17e-05	178	126	6	d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell	facs-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 ALDH1L1 CCKAR PAH RETREG1 PLA2G1B	1.33e-05	182	126	6	45faefd7cbeac84d2c58650530b902af6ce921f8
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	SGO1 ESCO2 DDIAS GLMN KIF15 MTBP	1.37e-05	183	126	6	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	SGO1 ZNF786 PARS2 VIPAS39 GEMIN4 IPO13	1.46e-05	185	126	6	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO6 ABCA13 DNAH14 RANBP17 STK39 CCSER1	1.50e-05	186	126	6	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPHX2 ALDH1L1 GCNT2 ITPR1 STK39 CCSER1	1.55e-05	187	126	6	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 ALDH1L1 CCKAR PAH RETREG1 PLA2G1B	1.55e-05	187	126	6	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 MYO6 ALDH1L1 ITPR1 COQ8A PAH	1.55e-05	187	126	6	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GCNT2 PREX2 DNAH14 SLC32A1 CRACD PALS2	1.65e-05	189	126	6	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ESCO2 GSTM5 KIF15 FAM124A	1.80e-05	192	126	6	a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GCNT2 ZNF804A PREX2 SLC32A1 CRACD LUM	1.80e-05	192	126	6	6a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell	distal-Epithelial-Proximal_Ciliated\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 TIGD4 ALDH1L1 DNAI3 CRACD DNAH12	1.96e-05	195	126	6	abe7998421dc59bdae35c0c2251c4a1ebef5e021
ToppCell	distal-Epithelial-Proximal_Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 TIGD4 ALDH1L1 DNAI3 CRACD DNAH12	1.96e-05	195	126	6	0e3f74e0877d33c11f048b9be8394596cf5c9c4c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SGO1 ESCO2 RANBP17 FAM111A KIF15 VAV1	2.14e-05	198	126	6	50f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SGO1 ESCO2 RANBP17 FAM111A KIF15 VAV1	2.14e-05	198	126	6	dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	SYT6 ZNF804A ARHGEF10L ZNF518A TDRD12	4.12e-05	135	126	5	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 RAB17 KCTD4 MED24 EDRF1	4.42e-05	137	126	5	e9b88ad86b75454a8292a94879c5b665adc42744
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 PIGZ GSTM5 PIGW PLA2G1B	4.58e-05	138	126	5	615822e542f12aa83df1561e262b8d72bdefc60e
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C11orf42 SGO1 DNAI3 ESCO2 KIF15	5.24e-05	142	126	5	7bd05d0c0ac2dee0e6cc0f3c531f9154bf300c75
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C11orf42 SGO1 DNAI3 ESCO2 KIF15	5.24e-05	142	126	5	328d08ba2712cd42bb9846ac4d7453ae165b75e2
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C11orf42 SGO1 DNAI3 ESCO2 KIF15	5.24e-05	142	126	5	94774d3e598d074f48146b0b094705dc48af5a1f
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C11orf42 SGO1 DNAI3 ESCO2 KIF15	5.24e-05	142	126	5	92bf826827b3e3387ad326566556fc90c5c2f4d5
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLXNA3 LALBA RNF17 ESCO2 KIF15	8.44e-05	157	126	5	6730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 PIGZ ZNF451 TLR4 PIGW	8.69e-05	158	126	5	d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 STK26 ESCO2 KIF15 ADPGK	8.69e-05	158	126	5	1e7bf5f51a6582026b844095fc11434430a83dab
ToppCell	Control-Epithelial_airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 SYT6 KCTD4 PADI1 SPINK5	8.69e-05	158	126	5	35aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 PIGZ ZNF451 TLR4 PIGW	8.69e-05	158	126	5	df614450e10629dc9115d7365397663e82f9e48f
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 FMO4 GLS2 ALDH1L1 PAH	8.96e-05	159	126	5	0f6ff73410fd6a6f97a53cb865952963a73848dd
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 RNF17 DNAI3 FAM124A LUM	9.22e-05	160	126	5	8590281165eab6514a9f6a022b900d4c222c1044
ToppCell	Healthy_donor-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	EPHX2 METTL24 RETREG1 CCR7 ATM	9.50e-05	161	126	5	8a61395af33132783a0a37956c6f821aba5d3b1e
ToppCell	droplet-Heart-4Chambers\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM5 CRACD COQ8A PLAGL1 LUM	9.78e-05	162	126	5	5625ec6dae204d5537883f05ea546970628d10bb
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SGO1 ZNF518A ZNF451 CCR7 CCSER1	1.01e-04	163	126	5	3087224d3f16f5d3aecc3e1e4366220231afe31f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TIGD4 SGO1 ESCO2 KIF15 OSBPL5	1.01e-04	163	126	5	466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCell	droplet-Liver-Hepatocytes-21m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ALDH1L1 COQ8A PAH	1.04e-04	164	126	5	c9866a289e120be4066e66275c3beb97ba67cca4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT6 SLC32A1 DDIAS TRANK1 WDR17	1.07e-04	165	126	5	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 ABCA13 SLFN14 STK39 ADPGK	1.07e-04	165	126	5	9acf03b5a20170721380045b5c268825e8f315dd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT6 SLC32A1 DDIAS TRANK1 WDR17	1.07e-04	165	126	5	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	droplet-Marrow-BM-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 ANXA11 SLFN14 STK39 ADPGK	1.10e-04	166	126	5	019d365df44c3bbd88c1f4bdceb3de0ff76d3e8d
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ALDH1L1 COQ8A PAH	1.10e-04	166	126	5	4b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 RAB17 SYT6 PPP4R4 SPINK5	1.10e-04	166	126	5	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 RAB17 SYT6 PPP4R4 SPINK5	1.10e-04	166	126	5	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ALDH1L1 COQ8A PAH	1.10e-04	166	126	5	d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	SGO1 ZNF804A ESCO2 DDIAS KIF15	1.13e-04	167	126	5	315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCell	droplet-Spleen-nan-21m-Myeloid-granulocyte\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0513 ABCA13 EDNRA STK39 ADPGK	1.13e-04	167	126	5	cfcd72292c733cdb18c92fdb61b68f6806d22c8c
ToppCell	Control-Epithelial_airway-Club_cells-Airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 SYT6 KCTD4 PADI1 SPINK5	1.16e-04	168	126	5	ce87981f4da2779de952c2e5d2bbcdabb265e705
ToppCell	Substantia_nigra-Endothelial-MURAL\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TIGD4 GCNT2 EDNRA METTL24 MTBP	1.16e-04	168	126	5	271a81c59a9a75bac6107c68fead03e7f35bc192
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPHX2 CERKL DNAI3 DNAH12 AGK	1.16e-04	168	126	5	9a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell	Control-Epithelial_airway-Club_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 SYT6 KCTD4 PADI1 SPINK5	1.16e-04	168	126	5	e85bc5398eb36b2b0773a8a7082e3ba740452165
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TIGD4 GCNT2 EDNRA METTL24 MTBP	1.16e-04	168	126	5	b220e732eb7b204fc263a9f2e8ddae6bf9fa98f4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 PREX2 ARHGEF10L NUAK2 PALS2	1.23e-04	170	126	5	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	KIAA0513 SGO1 ESCO2 SLC32A1 KIF15	1.23e-04	170	126	5	73601c873b177d5d134618d8e228c51381119f7d
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	CERKL DNAI3 CRACD CCR7 ALPK2	1.23e-04	170	126	5	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	EPHX2 ARHGEF10 RETREG1 CCR7 ATM	1.23e-04	170	126	5	9a18756e6721980d4b6c37bb52ddfe93ca79c5ab
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic-Progen-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	EPHX2 ARHGEF10 RETREG1 CCR7 ATM	1.26e-04	171	126	5	61d622153b91702ef21b0efc7b9581e592b7ccea
ToppCell	systemic_lupus_erythematosus-treated-Hematopoietic-Progen\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	EPHX2 ARHGEF10 RETREG1 CCR7 ATM	1.26e-04	171	126	5	09b3fa120f63c411f8a0dd6bd230a9720ce83fb1
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ALDH1L1 COQ8A PAH	1.30e-04	172	126	5	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ALDH1L1 COQ8A PAH	1.30e-04	172	126	5	9adfb4a65669cc536343616637058d0a4728013f
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 GLS2 ALDH1L1 COQ8A PAH	1.30e-04	172	126	5	8aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.33e-04	173	126	5	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERKL KIAA0513 ARHGEF10L TGM3 CLCN6	1.33e-04	173	126	5	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.33e-04	173	126	5	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AADACL4 SLFN14 SGO1 ESCO2 KIF15	1.33e-04	173	126	5	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GNG14 DDIAS CRACD KIF15 ACCS	1.33e-04	173	126	5	f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERKL FMO2 TLR8 PREX2 CCR7	1.33e-04	173	126	5	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERKL KIAA0513 ARHGEF10L TGM3 CLCN6	1.33e-04	173	126	5	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.37e-04	174	126	5	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CERKL RAB17 DNAH12 PLA2G1B CCSER1	1.37e-04	174	126	5	3503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.37e-04	174	126	5	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	droplet-Heart-4Chambers-21m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM5 CRACD COQ8A PLAGL1 LUM	1.37e-04	174	126	5	f098778ea74012861ec74b425e45776a31f67679
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.44e-04	176	126	5	60740f676db5d259ef3046bd5bc7b7b14924ecee
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 STBD1 STK26 SLC32A1 PAH	1.52e-04	178	126	5	d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 STBD1 STK26 SLC32A1 PAH	1.52e-04	178	126	5	b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 STBD1 STK26 SLC32A1 PAH	1.52e-04	178	126	5	0f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCTD4 ZNF804A DNAH14 PPP4R4 SEC24D	1.56e-04	179	126	5	1ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ALDH1L1 PAH RETREG1 PALS2 ALPK2	1.60e-04	180	126	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	MatrixFB-Fibroblast-A\|MatrixFB / shred on cell class and cell subclass (v4)	FMO2 STBD1 MYO6 PREX2 PPP4R4	1.60e-04	180	126	5	adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	GBF1 TLR6 ZNF786 RECQL5 AGK	1.64e-04	181	126	5	c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO6 ABCA13 DNAH14 RANBP17 STK39	1.64e-04	181	126	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.64e-04	181	126	5	cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK26 SYT6 PPP4R4 SLC32A1 TRANK1	1.69e-04	182	126	5	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.69e-04	182	126	5	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCell	droplet-Pancreas-PANCREAS-30m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 CCKAR PAH RETREG1 PLA2G1B	1.69e-04	182	126	5	cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SGO1 ESCO2 KIF15 ADPGK	1.69e-04	182	126	5	9025178ede571e3808d4657ad4892152f336c9b4
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SGO1 ESCO2 KIF15 ADPGK	1.69e-04	182	126	5	c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK26 SYT6 PPP4R4 SLC32A1 TRANK1	1.69e-04	182	126	5	6cde859edfe7607bd7ada89d20258413d06f4207
Drug	Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A	TPST1 FMO4 GLS2 ANXA11 SMURF1 ZNF318 RANBP17 RECQL5 PLAGL1	1.65e-06	200	125	9	6270_DN
Drug	Fluvoxamine maleate [61718-82-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A	PLXNA3 TPST1 FMO4 ZNF318 CLCN6 RECQL5 PLAGL1 PADI1	1.30e-05	196	125	8	7333_UP
Drug	Carteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	EPHX2 KIAA0513 SMURF1 PREX2 ARHGEF10 RETREG1 PLA2G1B EDRF1	1.35e-05	197	125	8	4096_DN
Drug	Enilconazole [35554-44-0]; Down 200; 13.4uM; MCF7; HT_HG-U133A	FMO4 SMURF1 ZNF318 PREX2 ARHGEF10L USP21 VAV1 PADI1	1.45e-05	199	125	8	5538_DN
Drug	Meglumine [6284-40-8]; Up 200; 20.4uM; HL60; HT_HG-U133A	KIAA0513 MYO6 NOX5 ALDH1L1 GCNT2 TRANK1 RECQL5 PADI1	1.51e-05	200	125	8	3068_UP
Disease	ataxia telangiectasia (implicated_via_orthology)	ATR ATM	1.75e-05	2	124	2	DOID:12704 (implicated_via_orthology)
Disease	xanthosine measurement	FMO2 FMO4 CCSER1	1.56e-04	25	124	3	EFO_0010549
Disease	anogenital venereal wart (is_marker_for)	MYD88 TLR8 TLR4	1.75e-04	26	124	3	DOID:11168 (is_marker_for)
Disease	Ventricular Dysfunction, Left	EPHX2 TLR4 ATM	2.71e-04	30	124	3	C0242698
Disease	Eosinophilia, Tropical	MYD88 TLR4	3.63e-04	7	124	2	C0014458
Disease	E3 ubiquitin-protein ligase ZNRF3 measurement	SLFN14 PPP4R4	3.63e-04	7	124	2	EFO_0021943
Disease	Eosinophilia	MYD88 TLR4	4.82e-04	8	124	2	C0014457
Disease	Inherited neuropathies	ITPR1 COQ8A ATM	6.39e-04	40	124	3	C0598589
Disease	coronary artery disease (is_implicated_in)	EPHX2 CLCN6 TLR4 LUM	8.53e-04	100	124	4	DOID:3393 (is_implicated_in)
Disease	neurotic disorder	ZNF804A MED24 TLR4 CCSER1	8.86e-04	101	124	4	EFO_0004257
Disease	Gastric Adenocarcinoma	STK26 TRRAP ATM	9.04e-04	45	124	3	C0278701
Disease	Bipolar Disorder	ABCA13 ZNF804A CCKAR ITPR1 TRANK1 ARHGEF10 TLR4 PLA2G1B	9.44e-04	477	124	8	C0005586
Disease	Methionine sulfoxide measurement	FMO2 FMO4	1.12e-03	12	124	2	EFO_0021650
Disease	niacinamide measurement	FMO2 FMO4	1.12e-03	12	124	2	EFO_0010511
Disease	pulmonary emphysema (implicated_via_orthology)	EDNRA TLR4	1.33e-03	13	124	2	DOID:9675 (implicated_via_orthology)
Disease	Depressed mood	MYD88 TRIM69	1.33e-03	13	124	2	C0344315
Disease	diffuse plaque measurement	CERKL FMO2 FMO4 ABCA13 ALDH1L1 DNAH14 ACCS FAM124A STK39 CCSER1	1.39e-03	758	124	10	EFO_0010699
Disease	gamma-glutamylglutamate measurement	ZNF318 EIF2AK4	1.54e-03	14	124	2	EFO_0021137
Disease	Congenital total cataract	GCNT2 AGK	2.02e-03	16	124	2	C0266539
Disease	obesity (implicated_via_orthology)	GNG14 CCKAR ITPR1 GSTM5 TLR4	2.19e-03	215	124	5	DOID:9970 (implicated_via_orthology)
Disease	Benign neoplasm of stomach	ATR ATM	2.29e-03	17	124	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ATR ATM	2.29e-03	17	124	2	C0496905
Disease	Carcinoma in situ of stomach	ATR ATM	2.29e-03	17	124	2	C0154060
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR6 TLR4	2.29e-03	17	124	2	DOID:8677 (biomarker_via_orthology)
Disease	Colorectal Carcinoma	ABCA13 ALDH1L1 ZNF804A PREX2 NCDN ARHGEF10L ZNF43 TLR4 EDRF1	2.91e-03	702	124	9	C0009402
Disease	dehydroepiandrosterone sulphate measurement	ABCA13 ZNF394 EIF2AK4	2.97e-03	68	124	3	EFO_0007001
Disease	Stomach Carcinoma	ATR ATM	3.49e-03	21	124	2	C0699791
Disease	hepatitis B (is_marker_for)	MYD88 PREX2	3.49e-03	21	124	2	DOID:2043 (is_marker_for)
Disease	carotid artery disease (is_implicated_in)	TLR4 LUM	3.83e-03	22	124	2	DOID:3407 (is_implicated_in)
Disease	Ovarian Serous Adenocarcinoma	STK36 TRRAP	4.18e-03	23	124	2	C1335177

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCNKDPFALKSLTYL	TPST1	156	O60507
KFAANSDLKVLLCGP	ADPGK	166	Q9BRR6
FLNPAACKGKARTLF	AGK	66	Q53H12
KTCATKPAFLEFLKQ	ARHGEF10	531	O15013
KACLTKPAFLEFLKR	ARHGEF10L	426	Q9HCE6
LLLKTCEPKTANAFK	ARSD	26	P51689
LDFANKKSCFLCLPL	C1orf140	41	Q5VVS0
VKCLKNTPAFFAERL	ANXA11	426	P50995
SDLPADFQDFLKKCV	EIF2AK4	506	Q9P2K8
LDNKVLLSFGKAFEC	ACCS	436	Q96QU6
TAFFKKFLTCPKILE	ALPK2	1386	Q86TB3
DLFKLFKDLGCLSQE	CCR7	336	P32248
IPKDTDKACLKGLFQ	ABCA13	4116	Q86UQ4
IFFDKKALSFPCSLK	AADACL4	381	Q5VUY2
FLCKLFPFLQKSSVG	EDNRA	156	P25101
PSLCLSNFLKDKELA	CCSER1	786	Q9C0I3
PNLLKDFIFGSAVCK	CCKAR	101	P32238
ANLLKPIDDFCTKFF	DNAI3	621	Q8IWG1
KNDFKSILPTVGCAF	RAB17	41	Q9H0T7
LACSLLKEVFAKPLN	RANBP17	191	Q9H2T7
LLASPSACLKLFQEK	PADI1	491	Q9ULC6
QVFFCGSPALAKVLK	NOX5	736	Q96PH1
LAFGLNKKLCNDFLK	KIAA0513	371	O60268
FKDNSLDAPVKLCDF	MAPKAPK5	156	Q8IW41
LDAPVKLCDFGFAKI	MAPKAPK5	161	Q8IW41
AQKEPCLFANTEKLK	KIF15	571	Q9NS87
KAEDASKFELCQLLP	NCDN	231	Q9UBB6
EPKCLDAFLNLKDFI	GSTM5	171	P46439
LKQIFKLLQAPFTDC	ITPR1	516	Q14643
KAAKLFQLLKDAPCE	EDRF1	1061	Q3B7T1
KLFCPQDKKFFQSLD	SPINK5	41	Q9NQ38
FKGAVKQLLSCFPNA	GCNT2	136	Q8N0V5
KQLLSCFPNAFLASK	GCNT2	141	Q8N0V5
CFPNAFLASKKESVV	GCNT2	146	Q8N0V5
ALFPACVLKNAELKF	DDX1	226	Q92499
KKADFCIFPIFSNLD	FAM124A	201	Q86V42
TFLLHKFLKECAGEP	PLXNA3	1421	P51805
SKDDFLFNCKGNLSP	DDIAS	491	Q8IXT1
FFEEPLKSLCTKKIF	FMO4	336	P31512
LKKCFEGIAKLEFLP	DNAH12	1021	Q6ZR08
EKDKLLFSFLLCANL	DNAH12	2341	Q6ZR08
RIFCNAPDFISKIKS	KCTD4	156	Q8WVF5
GILFPAILAKQFTKC	LALBA	11	P00709
KECDFQTKFALSLSP	MYD88	231	Q99836
LLKFCTEQAKNDPFL	GNG14	36	A0A1W2PPG7
KFLIEACKVNPFAKD	GLS2	536	Q9UI32
CLKPDLLDFTFEGKL	NPEPPSL1	66	A6NEC2
LPLNFLSGEKFKECL	NAA15	296	Q9BXJ9
FGELQYCLSEKPKLL	PAH	351	P00439
EFADPFKLAECKLAI	NUP155	1191	O75694
LAFSFDPKLQKFLKC	GPRC6A	686	Q5T6X5
DNLIPCKEAGLKFSK	PALS2	231	Q9NZW5
FQPAKCTDKENALKL	FAM189A2	56	Q15884
ADICKSLASFIKKPF	ATM	816	Q13315
SQLKASVCKPFLFLL	ATR	756	Q13535
LLNFGEFKCSDSDKK	CLCN6	311	P51797
CLPKNFSIKEIFDKA	EPHX2	81	P34913
IKDALCKDGRFLSFL	FAM111A	221	Q96PZ2
TEGCKFAKDLPSFLV	CRACD	786	Q6ZU35
SFLICSKLKARFPCK	COQ8A	616	Q8NI60
AKLKAEDCEISFLPF	CERKL	381	Q49MI3
CKTLLEKPKLFFIQA	CASP7	171	P55210
ALFAFKCNTALIKLP	DNAH14	1181	Q0VDD8
LEKFDIKSFCKILGP	LUM	286	P51884
KCPNKIKTFLFISDE	ESCO2	471	Q56NI9
LEIGAKPDFCSLLFK	FMO2	441	Q99518
ESCFNKVLFPLLTKL	GBF1	1586	Q92538
LNADLKKLNCSPDSF	SEC24B	546	O95487
KAVFQCAVLALKFPE	IPO13	816	O94829
KFLIPKFFELCSDAV	PPP4R1L	201	Q9P1A2
CLKPDLLDFTFEGKL	NPEPPS	66	P55786
KCFLPDEFNIATGKL	PYDC5	26	W6CW81
FPEFCLKGVTLKNFS	MTBP	256	Q96DY7
AFVPAILFKDNEKSC	UPF2	476	Q9HAU5
LIERPSKKDGFCFKL	OSBPL5	176	Q9H0X9
PQLFLKKDIFNASSC	METTL24	341	Q5JXM2
DELLKFCFKSLKCPL	GLMN	206	Q92990
LKAFDLPAKDFCGSS	SYT6	251	Q5T7P8
CSLFNKLGLPFVKVQ	PARS2	231	Q7L3T8
KLAANFGKLCTVPLD	SNX13	361	Q9Y5W8
LPLKADTKGFCNISL	PLAGL1	316	Q9UM63
EVQFKPESLCKKLFS	SLFN14	401	P0C7P3
ILPLVKSFCEKSFKA	PPP4R4	291	Q6NUP7
LSFIPFARDAVKKCF	SFT2D2	141	O95562
FLELPFQALEFKICK	TDRD9	1001	Q8NDG6
SLFKQQSPGKFCLLV	RETREG1	186	Q9H6L5
SFKEFIDACLNKDPS	STK26	246	Q9P289
ECFLVDFAKNIPVKS	TDRD12	91	Q587J7
FLFTCSQRKPQADLK	PKDREJ	1446	Q9NTG1
CAFEFLLKLTPLLDK	MED24	336	O75448
DLCFLNSPIFKQKKD	SGO1	501	Q5FBB7
QAKKLDSCKFLLDNP	PLA2G1B	76	P04054
IFDCKFKPDDPNLLA	WDR17	396	Q8IZU2
VFKLSSLLCKFSPDG	WRAP73	6	Q9P2S5
RPLLENGAKVCSFFK	NUAK2	341	Q9H093
EALKAADCPGKLFIF	SEC24D	566	O94855
CAKNLAKKDFFRLPD	SMURF1	21	Q9HCE7
CFKNFLQGLLTKDPR	STK36	226	Q9NRP7
SFAKFLIKGALVPCS	PIGW	396	Q7Z7B1
LLADFSCNKFPAIKA	TGM3	671	Q08188
GKSPLIIFADCDLNK	ALDH1L1	676	O75891
LPVAFSCLKFSLQSK	C11orf42	191	Q8N5U0
SDPYGNLKDFCLKAL	RECQL5	236	O94762
FLNAPEKAIKCKLAY	RNF17	781	Q9BXT8
LPFQACLKVEKFGDL	PRPF8	1891	Q6P2Q9
NLKLFSKPDGKLICF	TRIM69	121	Q86WT6
DPSKECFTLKFDLNV	PLEKHG5	71	O94827
KPQCAAYGKALDLSL	TLR8	476	Q9NR97
FPSFAKKLLISLCKD	ZNF451	296	Q9Y4E5
LFLPVNFCFLKLKNS	nan	16	Q6ZQY7
LQEAFQGKRPLFSKC	ZNF394	221	Q53GI3
VFCDLSLPIPKKGFA	USP21	396	Q9UK80
ATCFAEKLPSSNLLK	STBD1	166	O95210
KDCFKSLDTTLQFPF	VAV1	751	P15498
VKNLKSIELAFFPSC	TIGD4	296	Q8IY51
AALCKKYADLGNSPL	TXLNGY	116	Q9BZA5
RKLTTFPKCFLGSEF	PREX2	401	Q70Z35
KEFLKTCVGLPFSAE	VIPAS39	271	Q9H9C1
TFLPDGKQAVFLKCV	ZNF518A	1096	Q6AHZ1
VEKCSFPFKNETLLF	PIGZ	531	Q86VD9
LDLSFNDFKALPICK	TLR6	126	Q9Y2C9
QCLPATQSKIFLFDK	ZNF43	136	P17038
FQCPKCDKSFRLKAQ	ZNF786	676	Q8N393
LLPCAFLKNLKAVSK	SLC32A1	251	Q9H598
IKSFLKGSFEALSCP	TRANK1	1306	O15050
PTAAELLKCKFFQKA	STK39	326	Q9UEW8
ELVNCKFGQFPTLKL	TLR4	336	O00206
TKFLKLNVEKAPFLC	TXNDC9	121	O14530
PKFFLIEEKCRFLSN	TRRAP	3456	Q9Y4A5
KDNSPLREKFGSFLC	ZNF318	461	Q5VUA4
SEKDALLLPSFCKFQ	ZNF804A	301	Q7Z570
PALLFKLAQDACKTA	ZSWIM4	641	Q9H7M6
CYADLSLPGKNKVLA	GEMIN4	486	P57678
KLLLKFITFPDGCQD	NLRP14	706	Q86W24
PRLFCKALFKALGLN	MYO6	731	Q9UM54