Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

8.17e-0521812GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

8.17e-0521812GO:0044017
GeneOntologyMolecularFunctionsterol O-acyltransferase activity

SOAT2 SOAT1

2.44e-0431812GO:0004772
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

2.44e-0431812GO:0043993
GeneOntologyMolecularFunctioncholesterol O-acyltransferase activity

SOAT2 SOAT1

2.44e-0431812GO:0034736
GeneOntologyCellularComponentendoplasmic reticulum exit site

CTAGE9 CTAGE6 PREB CTAGE8 SEC16A CTAGE15 CTAGE4

6.79e-08421817GO:0070971
HumanPhenoCervical cord compression

EXTL3 IDS CREBBP EP300

1.37e-069544HP:0002341
HumanPhenoDeviated nasal septum

CREBBP PAH EP300

3.83e-057543HP:0004411
HumanPhenoSpinal cord compression

DDR2 EXTL3 IDS CREBBP EP300

8.80e-0544545HP:0002176
HumanPhenoPilomatrixoma

CREBBP KMT2D EP300

9.04e-059543HP:0030434
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

1.10e-042542HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

1.10e-042542HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

1.10e-042542HP:0001042
HumanPhenoHypoplastic left heart

CREBBP ZIC3 KMT2D PAH EP300

1.48e-0449545HP:0004383
HumanPhenoCongenital malformation of the left heart

CREBBP ZIC3 KMT2D PAH EP300

1.80e-0451545HP:0045017
HumanPhenoHypoplastic heart

CREBBP ZIC3 KMT2D PAH EP300

2.36e-0454545HP:0001961
HumanPhenoDislocated radial head

EXTL3 CREBBP DCHS1 NIPBL EP300

2.36e-0454545HP:0003083
HumanPhenoAbnormality of the radial head

EXTL3 CREBBP DCHS1 NIPBL EP300

3.06e-0457545HP:0003995
HumanPhenoSelf-injurious behavior

ATP6V0A1 CREBBP MADD UBAP2L PAH DCHS1 NIPBL EP300 UNC80

3.06e-04210549HP:0100716
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

3.29e-043542HP:0008752
HumanPhenoPhobia

CREBBP EP300

3.29e-043542HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

3.29e-043542HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

3.29e-043542HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

3.29e-043542HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

3.29e-043542HP:0005895
HumanPhenoPneumonia

ATP6V0A1 DDR2 EXTL3 IDS CREBBP KMT2D CSF2RA NOS1 NIPBL EP300 MASP2

3.30e-043115411HP:0002090
HumanPhenoHypoplastic aortic arch

CREBBP ZIC3 EP300

3.77e-0414543HP:0012304
DomainMAGE

MAGEA1 MAGEA8 MAGED1 TRO MAGEF1 MAGEC1

6.50e-07341746SM01373
DomainMAGE

MAGEA1 MAGEA8 MAGED1 TRO MAGEF1 MAGEC1

9.26e-07361746PS50838
DomainMHD_dom

MAGEA1 MAGEA8 MAGED1 TRO MAGEF1 MAGEC1

9.26e-07361746IPR002190
DomainMAGE

MAGEA1 MAGEA8 MAGED1 TRO MAGEF1 MAGEC1

9.26e-07361746PF01454
DomainNuc_rcpt_coact

PALMD CREBBP EP300

1.56e-0561743IPR009110
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

8.63e-0521742IPR014744
DomainZnF_TAZ

CREBBP EP300

8.63e-0521742SM00551
Domain-

CREBBP EP300

8.63e-05217421.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

8.63e-0521742IPR010303
Domain-

CREBBP EP300

8.63e-05217421.10.1630.10
DomainCreb_binding

CREBBP EP300

8.63e-0521742PF09030
Domainzf-TAZ

CREBBP EP300

8.63e-0521742PF02135
DomainZF_TAZ

CREBBP EP300

8.63e-0521742PS50134
DomainSterol_acyltranf_meta

SOAT2 SOAT1

8.63e-0521742IPR030687
DomainKAT11

CREBBP EP300

8.63e-0521742SM01250
DomainZnf_TAZ

CREBBP EP300

8.63e-0521742IPR000197
DomainKIX

CREBBP EP300

8.63e-0521742PF02172
DomainHAT_KAT11

CREBBP EP300

8.63e-0521742PF08214
DomainKIX

CREBBP EP300

8.63e-0521742PS50952
DomainCBP_P300_HAT

CREBBP EP300

8.63e-0521742IPR031162
DomainDUF902

CREBBP EP300

8.63e-0521742PF06001
Domain-

CREBBP EP300

8.63e-05217421.10.246.20
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

8.63e-0521742IPR013178
DomainKIX_dom

CREBBP EP300

8.63e-0521742IPR003101
DomainCBP_P300_HAT

CREBBP EP300

8.63e-0521742PS51727
DomainZO

TJP1 TJP3

2.57e-0431742IPR005417
DomainOat_ACAT_DAG_ARE

SOAT2 SOAT1

2.57e-0431742IPR014371
DomainGal_mutarotase_N

SI MGAM2

5.11e-0441742IPR031727
DomainPept_S1A_C1r/C1S/mannan-bd

C1R MASP2

5.11e-0441742IPR024175
DomainNtCtMGAM_N

SI MGAM2

5.11e-0441742PF16863
DomainCadherin_CS

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

5.50e-041091746IPR020894
DomainCADHERIN_1

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

6.65e-041131746PS00232
DomainCadherin

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

6.65e-041131746PF00028
DomainCADHERIN_2

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

6.97e-041141746PS50268
Domain-

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

6.97e-0411417462.60.40.60
DomainCA

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

7.30e-041151746SM00112
DomainCadherin-like

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

7.64e-041161746IPR015919
DomainCadherin

PCDHGB6 PCDH11Y PCDH11X PCDH15 DCHS1 CDH7

8.35e-041181746IPR002126
DomainProtocadherin

PCDH11Y PCDH11X

8.47e-0451742PF08374
DomainProtocadherin

PCDH11Y PCDH11X

8.47e-0451742IPR013585
DomainGUANYLATE_KINASE_2

MAGI2 TJP1 TJP3

1.23e-03231743PS50052
DomainGUANYLATE_KINASE_1

MAGI2 TJP1 TJP3

1.23e-03231743PS00856
DomainGlyco_hydro_31_AS

SI MGAM2

1.26e-0361742IPR030458
DomainGlyco_hydro_31

SI MGAM2

1.76e-0371742IPR000322
DomainGlyco_hydro_31

SI MGAM2

1.76e-0371742PF01055
Domain-

ARRDC3 ARRDC2

1.76e-03717422.60.40.640
DomainGLYCOSYL_HYDROL_F31_1

SI MGAM2

1.76e-0371742PS00129
DomainGuanylate_kin

MAGI2 TJP1 TJP3

1.76e-03261743PF00625
DomainGK/Ca_channel_bsu

MAGI2 TJP1 TJP3

1.76e-03261743IPR008145
DomainGuanylate_kin-like_dom

MAGI2 TJP1 TJP3

1.76e-03261743IPR008144
DomainBromodomain_CS

CREBBP BRPF1 EP300

1.76e-03261743IPR018359
DomainGuKc

MAGI2 TJP1 TJP3

1.76e-03261743SM00072
DomainFN3

NPHS1 COL6A3 PTPRC CSF2RA TNR PHYHIPL MYBPC3

1.77e-031851747SM00060
DomainArrestin_C

ARRDC3 ARRDC2

2.33e-0381742IPR014752
DomainRBM1CTR

RBMXL1 RBMX

2.33e-0381742PF08081
DomainRBM1CTR

RBMXL1 RBMX

2.33e-0381742IPR012604
DomainTrefoil

SI MGAM2

2.33e-0381742PF00088
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PDS5B LEO1 RBBP6 CDK12 REXO1 CLASRP USP10 KMT2D PTPRC GSE1 UBAP2L ZC3H4 CHTF18 RBMX BRPF1 SEC16A NIPBL XRCC6 SON

3.51e-087741841915302935
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PDS5B STXBP5 TRO MADD MAGI2 PXDN GSE1 UBAP2L SEC16A TCF25 CACNA1H ARRDC3 EPB41L1 SON

4.21e-084071841412693553
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

LEO1 RBBP6 CDK12 PLEKHA6 USP10 MAVS UBAP2L ZC3H4 RBMX SEC16A PXN NIPBL ANKS3 EPB41L1 SON

8.81e-085031841516964243
Pubmed

Connexin45 directly binds to ZO-1 and localizes to the tight junction region in epithelial MDCK cells.

GJC1 TJP1 TJP3

1.46e-073184311557048
Pubmed

Non-clustered protocadherin.

PCDH11Y PCDH11X PCDH15

1.46e-073184321173574
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

CREBBP KMT2D EP300

5.80e-074184328398509
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

MAGED1 RBBP6 CDK12 TRO RC3H1 MSI1 MRPL4 USP10 UBAP2L RBMX SEC16A TCF25 QSER1 XRCC6 SON CKMT1A

7.46e-076781841630209976
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD ATP6V0A1 MAGED1 LEO1 TRIOBP DAZAP2 EXTL3 IDS CREBBP MADD ZIC3 METAP1 MAGI2 USP2 TJP1 ZBTB11 NIPBL SNTA1 EP300 XRCC6 SCAI ZNF292

1.38e-0612851842235914814
Pubmed

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.

CREBBP EP300 XRCC6

1.45e-065184315023334
Pubmed

Physical association between the histone acetyl transferase CBP and a histone methyl transferase.

CREBBP SUV39H1 EP300

1.45e-065184311252719
Pubmed

Regulation of murine TGFbeta2 by Pax3 during early embryonic development.

CREBBP TGFB2 EP300

1.45e-065184316787918
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DENND4A MAGED1 LEO1 CDK12 C15orf39 AMBRA1 MADD PREB GSE1 ZC3H4 CHTF18 TCF25 QSER1 ZBTB11 EPB41L1

2.20e-066501841538777146
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ATP6V0A1 MAP1A STXBP5 BCAN PLEKHA6 MADD MAGI2 UBAP2L AJM1 SNTA1 EPB41L1

2.71e-063471841117114649
Pubmed

Jun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator.

CREBBP PGR EP300

5.02e-067184312101239
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

CDK12 KMT2D GSE1 NIPBL EP300 ZNF292

5.44e-0683184628794006
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ENGASE PLXNA3 SH3RF1 CDK12 C15orf39 AMBRA1 EXTL3 REXO1 MADD KMT2D NUAK1 SEC16A PXN CACNA1H ARRDC2 EP300 GAREM1 ATPAF2 TJP3

7.15e-0611051841935748872
Pubmed

Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.

CREBBP EP300 XRCC6

8.00e-068184315075319
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MAGED1 MAP1A RC3H1 KPRP TRIOBP USP10 UBAP2L TJP1 ZC3H4 BRPF1 PXN LSM14B SON ZNF292 INO80E

8.05e-067241841536232890
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PLXNA3 PDS5B KNTC1 DENND4A LEO1 RBMXL1 PCDHGB6 TRO RGS11 CTAGE6 NEB PXDN TJP1 RBMX CTAGE8 CTAGE15 CTAGE4 ZBTB11 NIPBL XRCC6 ZNF292 ATPAF2

8.69e-0614421842235575683
Pubmed

Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

RBBP6 KCTD8 TRIOBP TCF25 TNR NIPBL SCAI

1.18e-05143184732560809
Pubmed

HIV-1 chromatin, transcription, and the regulatory protein Tat.

CREBBP CCNT1 EP300

1.20e-059184324158816
Pubmed

Immune evasion strategy involving propionylation by the KSHV interferon regulatory factor 1 (vIRF1).

CREBBP USP10 EP300

1.70e-0510184337023208
Pubmed

The transcriptional co-repressor TLE3 suppresses basal signaling on a subset of estrogen receptor α target genes.

FOXA1 CREBBP EP300

1.70e-0510184325223786
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

MAGED1 RC3H1 C15orf39 CREBBP GSE1 AMOTL1 EP300

1.75e-05152184738360978
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

MAGED1 CDK12 GJC1 AMBRA1 RGS11 MSI1 MRPL4 USP10 UBAP2L ZC3H4 RBMX TCF25 LSM14B ZBTB11 XRCC6 MASP2 CKMT1A

1.77e-059711841733306668
Pubmed

Interaction network of human early embryonic transcription factors.

KPRP C15orf39 CREBBP KMT2D GSE1 SEC16A QSER1 NIPBL EP300 INO80E

1.95e-053511841038297188
Pubmed

Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.

MAGEA1 MAGED1 MAGEF1

2.33e-0511184324911587
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

2.78e-052184227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

2.78e-052184234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

2.78e-052184219729597
Pubmed

CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation.

LEO1 CDK12

2.78e-052184237205756
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

2.78e-052184239287984
Pubmed

Neuropilin 2/Plexin-A3 Receptors Regulate the Functional Connectivity and the Excitability in the Layers 4 and 5 of the Cerebral Cortex.

PLXNA3 NRP2

2.78e-052184235534225
Pubmed

A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2.

SOAT2 SOAT1

2.78e-052184216647063
Pubmed

Connexin45 interacts with zonula occludens-1 in osteoblastic cells.

GJC1 TJP1

2.78e-052184212064590
Pubmed

Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.

PCDH11Y PCDH11X

2.78e-052184211003707
Pubmed

Pcdh11x Negatively Regulates Dendritic Branching.

PCDH11Y PCDH11X

2.78e-052184225687328
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

2.78e-052184220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

2.78e-052184225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

2.78e-052184211559821
Pubmed

Next generation sequencing identified two novel mutations in NIPBL and a frame shift mutation in CREBBP in three Chinese children.

CREBBP NIPBL

2.78e-052184230770747
Pubmed

Organization of human ACAT-2 gene and its cell-type-specific promoter activity.

SOAT2 SOAT1

2.78e-052184211401500
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

2.78e-052184232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

2.78e-052184219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

2.78e-052184224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

2.78e-052184221847097
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

2.78e-052184234813504
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

2.78e-052184220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

2.78e-052184224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

2.78e-052184237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

2.78e-052184211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

2.78e-052184210918613
Pubmed

Quantitative analysis of the expression of ACAT genes in human tissues by real-time PCR.

SOAT2 SOAT1

2.78e-052184214729857
Pubmed

Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.

PCDH11Y PCDH11X

2.78e-052184222592879
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

2.78e-052184235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

2.78e-052184231898871
Pubmed

Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.

PCDH11Y PCDH11X

2.78e-052184214727141
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

2.78e-052184230888860
Pubmed

Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues.

TJP1 TJP3

2.78e-052184214622136
Pubmed

Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex.

NOS1 SNTA1

2.78e-052184210221915
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

2.78e-052184227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

2.78e-052184219272189
Pubmed

Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.

PCDH11Y PCDH11X

2.78e-052184221276771
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

2.78e-052184232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

2.78e-052184230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

2.78e-052184221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

2.78e-05218429811832
Pubmed

Association of neuronal nitric oxide synthase (nNOS) with alpha1-syntrophin at the sarcolemma.

NOS1 SNTA1

2.78e-052184211747091
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

2.78e-052184224089570
Pubmed

A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.

CREBBP KMT2D

2.78e-052184227999180
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

2.78e-052184215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

2.78e-052184239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

2.78e-052184222303793
Pubmed

Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.

PCDH11Y PCDH11X

2.78e-052184216874762
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

2.78e-052184234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

2.78e-052184234019788
Pubmed

PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.

PCDH11Y PCDH11X

2.78e-052184216825765
Pubmed

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle.

NOS1 SNTA1

2.78e-052184220124730
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

2.78e-052184215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

2.78e-052184229460469
Pubmed

The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modern Homo sapiens.

PCDH11Y PCDH11X

2.78e-052184223600975
Pubmed

Investigating the allosterism of acyl-CoA:cholesterol acyltransferase (ACAT) by using various sterols: in vitro and intact cell studies.

SOAT2 SOAT1

2.78e-052184215992359
Pubmed

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells.

PRDM1 PTPRC

2.78e-052184228363897
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

2.78e-052184224551300
Pubmed

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.

SOAT2 SOAT1

2.78e-052184226982734
Pubmed

A comparative analysis of the pig, mouse, and human PCDHX genes.

PCDH11Y PCDH11X

2.78e-052184215112107
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

2.78e-052184233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

2.78e-05218429018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

2.78e-052184224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

2.78e-052184230135524
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

2.78e-052184216596650
Pubmed

Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains.

PCDH11Y PCDH11X

2.78e-052184222744706
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

2.78e-052184229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

2.78e-052184210049825
Pubmed

Vasomodulation by skeletal muscle-derived nitric oxide requires alpha-syntrophin-mediated sarcolemmal localization of neuronal Nitric oxide synthase.

NOS1 SNTA1

2.78e-052184212600881
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

2.78e-052184227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

2.78e-052184229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

2.78e-052184221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

2.78e-052184212646247
Pubmed

Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT).

SOAT2 SOAT1

2.78e-052184218000807
InteractionCTAGE1 interactions

CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.32e-06101834int:CTAGE1
Cytoband14q12-q13

NPAS3 FOXA1

1.60e-052184214q12-q13
Cytoband16p13.3

LMF1 RGS11 CREBBP CHTF18 CACNA1H DNASE1L2 ANKS3

6.25e-05244184716p13.3
Cytoband7q35

CTAGE6 CTAGE8 CTAGE15 CTAGE4

7.26e-055518447q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.48e-04661844chr7q35
GeneFamilyCTAGE family

CTAGE9 CTAGE6 CTAGE8 CTAGE15 CTAGE4

3.67e-08151225907
GeneFamilyMAGE family

MAGEA1 MAGEA8 MAGED1 TRO MAGEF1 MAGEC1

2.65e-074012261136
GeneFamilyAlpha arrestins

ARRDC3 ARRDC2

6.66e-04612221311
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MAGI2 TJP1 TJP3

6.96e-04261223904
CoexpressionLINDGREN_BLADDER_CANCER_CLUSTER_2B

COL6A3 MAP1A PDGFRL DDR2 RGS11 NRP2 THBS2 PXDN NUAK1 BRPF1 TCF25 C1R SON

4.07e-0638918413M4995
CoexpressionGSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_UP

ENGASE GSX1 RC3H1 SI RGS11 FOXRED2 KMT2D CDH7 INO80E

8.76e-061911849M8681
CoexpressionGSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN

RCCD1 DTX3 MAGEF1 REXO1 HOXA4 BRPF1 ARRDC2 ANKS3

1.38e-051541848M6824
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 PLEKHA6 USP2 CSN3 SOX14 ARHGAP27 SNTA1 CKMT1A TJP3

1.02e-0719018490bad41d19dc515e6bc61e699f4d56664cf2e72fd
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 PXDN HSPB6 CTAGE8 C1R

9.76e-07183184806a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD PALMD PGR THBS2 NUAK1 AMOTL1 NOS1 SLC27A3

1.19e-061881848ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A3 PDGFRL DDR2 OLFML3 TGFB2 THBS2 APCDD1L C1R

1.24e-06189184840764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A3 PDGFRL DDR2 OLFML3 TGFB2 THBS2 APCDD1L C1R

1.24e-061891848eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCellASK440-Mesenchymal|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL6A3 PDGFRL DDR2 RGS11 OLFML3 THBS2 HSPB6 C1R

1.35e-061911848f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL6A3 PDGFRL DDR2 OLFML3 TGFB2 THBS2 APCDD1L C1R

1.35e-06191184844b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCellASK440-Mesenchymal-Fibroblast|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL6A3 PDGFRL DDR2 RGS11 OLFML3 THBS2 HSPB6 C1R

1.35e-061911848387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 PRDM1 AMOTL1 PCDH11X PCDH15 NOS1 CDH7

1.45e-061931848d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 PRDM1 AMOTL1 PCDH11X PCDH15 NOS1 CDH7

1.45e-0619318483ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 NEB MADD PREB CSF2RA SEC16A UNC80 SON

1.45e-061931848471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 NEB MADD PREB CSF2RA SEC16A UNC80 SON

1.45e-061931848fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 PRDM1 AMOTL1 PCDH11X PCDH15 NOS1 CDH7

1.45e-061931848e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 PRDM1 AMOTL1 PCDH11X PCDH15 NOS1 CDH7

1.45e-061931848658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 NEB MADD PREB CSF2RA SEC16A UNC80 SON

1.51e-0619418483a3ecedcdc7691cf21775818b598208fcb980c29
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 PRDM1 AMOTL1 PCDH11X PCDH15 NOS1 CDH7

1.51e-06194184883863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 UST PRDM1 PCDH11X PCDH15 NOS1 CDH7

1.51e-0619418481bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 PLEKHA6 CSN3 SOX14 ARHGAP27 SNTA1 CKMT1A TJP3

1.57e-06195184825703e3c2e0512ef12e7aa389fad3968c3f13905
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 PXDN APCDD1L C1R

1.83e-0619918481fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LMF1 TRO BCAN PCDH15 TNR PHYHIPL NOS1 UNC80

1.83e-061991848e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1A PDGFRL DDR2 OLFML3 THBS2 PXDN HSPB6 C1R

1.83e-06199184821335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD COL6A3 PDGFRL OLFML3 PGR THBS2 AMOTL1 C1R

1.83e-061991848dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell356C-Fibroblasts-Fibroblast-F|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 MAP1A PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.83e-06199184859fe5f3c6338e019a149ab135acf9cc5657298bf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LMF1 TRO BCAN PCDH15 TNR PHYHIPL NOS1 UNC80

1.83e-061991848333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell356C-Fibroblasts-Fibroblast-F-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 MAP1A PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.83e-061991848136f24597ddca5cf2175120975c94782a3232ec6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD COL6A3 PDGFRL OLFML3 PGR THBS2 AMOTL1 C1R

1.83e-061991848c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

PCDH11Y BCAN UST PXDN PCDH11X PCDH15 TNR UNC80

1.90e-062001848961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

PCDH11Y BCAN UST PXDN PCDH11X PCDH15 TNR UNC80

1.90e-062001848f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

PCDH11Y BCAN UST PXDN PCDH11X PCDH15 TNR UNC80

1.90e-062001848cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

PCDH11Y BCAN UST PXDN PCDH11X PCDH15 TNR UNC80

1.90e-062001848c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LMF1 TRO BCAN THBS2 PCDH15 TNR PHYHIPL NOS1

1.90e-062001848ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

PCDH11Y BCAN UST PXDN PCDH11X PCDH15 TNR UNC80

1.90e-0620018484fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

PCDH11Y BCAN UST PXDN PCDH11X PCDH15 TNR UNC80

1.90e-062001848310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V0A1 MYADML2 C15orf39 ZIC3 PRDM1 ARFGAP3 CACNA1H

5.75e-06165184721a82a975f550080b6674750b06212205cd16742
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NPHS1 DDR2 RGS11 THBS2 KIAA1549L GLDC APCDD1L

7.27e-061711847bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GJC1 BCAN MSI1 KIAA1549L AMOTL1 DCHS1 C1R

8.45e-061751847f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellPericytes-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

MAP1A DDR2 GJC1 BCAN PGR HOXA4 HSPB6

9.45e-061781847a2448d868da2abe48c394c51264aad03e866dfec
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y KCTD8 PALMD BMP3 PXDN PCDH11X CACNA1H

9.80e-0617918477954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SH3RF1 DDR2 NPAS3 PLEKHA6 MAGI2 NUAK1 PCDH15

1.02e-05180184708ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 PDGFRL OLFML3 NRP2 THBS2 HSPB6 C1R

1.02e-051801847c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 PDGFRL OLFML3 NRP2 THBS2 HSPB6 C1R

1.02e-05180184732c6a3886428d82fb4355d987c6d2645f333447b
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SH3RF1 DDR2 NPAS3 PLEKHA6 MAGI2 NUAK1 PCDH15

1.02e-0518018479b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL6A3 SYT17 DDR2 PLA2G15 OLFML3 MAGI2 BMP3

1.05e-051811847ebf1ae963a2b22e1772752ed85a4fb0e546d377e
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SLFN5 PALMD NRP2 TJP1 CD36 ARHGAP27

1.05e-05181184792d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 MAP1A DDR2 RGS11 THBS2 HSPB6 C1R

1.05e-051811847c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 PDGFRL OLFML3 THBS2 HSPB6 APCDD1L C1R

1.05e-051811847e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 MAP1A DDR2 RGS11 THBS2 HSPB6 C1R

1.05e-051811847c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SLFN5 PALMD NRP2 TJP1 CD36 ARHGAP27

1.09e-05182184781279877b920b5a1bc991a07d3031d6458700fe3
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 HSPB6 APCDD1L C1R

1.09e-051821847d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LMF1 PCDHGB6 BCAN GSTA4 PCDH11X TNR PHYHIPL

1.13e-051831847a742c9a33f32058f9fb051733e3e736bc704d8e6
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

SH3RF1 DTX3 GJC1 RIPOR3 CD36 CACNA1H EPB41L1

1.13e-051831847273db6a3b00a93ca852498471187b642b5368185
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 OLFML3 PGR NUAK1 AK5 C1R

1.21e-051851847e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 OLFML3 PGR NUAK1 AK5 C1R

1.21e-0518518479d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 APCDD1L C1R

1.21e-05185184787c416d14ca6255bee39b16e7571553e36ee3069
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 DDR2 OLFML3 THBS2 HSPB6 PCDH15 C1R

1.26e-0518618475473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 PDGFRL RIPOR3 OLFML3 THBS2 HSPB6 C1R

1.26e-0518618477582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL OLFML3 PGR THBS2 HSPB6 C1R

1.26e-05186184707d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

SH3RF1 DTX3 GJC1 RIPOR3 CD36 CACNA1H EPB41L1

1.30e-051871847dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.35e-051881847e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD PALMD PGR TGFB2 THBS2 NUAK1 SLC27A3

1.39e-0518918472ce330d8078833c05775c481e73770f9ee4a5c88
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

OLFML3 HOXA4 THBS2 AK5 HSPB6 PCDH11X PCDH15

1.39e-0518918474f9608b84d135268a17455661870c46ae8554a24
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.39e-051891847d531399749409d614adca13d181830c6e3287508
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD PALMD PGR TGFB2 THBS2 NUAK1 SLC27A3

1.39e-051891847473c87036e04a058b4a5138438b7ba7e1e766799
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 USP2 CSN3 SOX14 SNTA1 CKMT1A TJP3

1.39e-05189184727e5d706f10a6221f314faf642eede15deab3165
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 PGR THBS2 C1R

1.49e-0519118470fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 RIPOR3 UST PGR PXDN C1R

1.49e-051911847a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.54e-051921847859a32c9e4ed6961897b2ccaecde73a599471df9
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.54e-05192184789e1da82fa2069dac7adb9cba3e8b6c0179e0dc5
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SLFN5 PALMD TGFB2 THBS2 AMOTL1 SLC27A3

1.54e-051921847c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 RIPOR3 UST PGR PXDN C1R

1.54e-0519218479093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 RIPOR3 UST PGR PXDN C1R

1.54e-0519218479ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A3 DDR2 UST MAGI2 THBS2 PCDH15 C1R

1.54e-051921847162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD SLFN5 PALMD TGFB2 THBS2 AMOTL1 SLC27A3

1.54e-051921847144503af50274eaed5cf6effa892c640eab28663
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 DDR2 OLFML3 PGR THBS2 HSPB6 C1R

1.54e-051921847c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCell21-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

GSX1 KCTD8 BCAN THBS2 PCDH11X C1R PHYHIPL

1.60e-0519318479a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y NPAS3 PRDM1 AMOTL1 PCDH11X PCDH15 NOS1

1.60e-0519318472189da4b727e25e62669d7b9257f06493be21a27
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A3 DDR2 RIPOR3 MAGI2 USP2 THBS2 C1R

1.60e-051931847261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

STXBP5 IDS MADD PGR TCF25 UNC80 CKMT1A

1.65e-0519418478aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.65e-051941847d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.65e-05194184702b8102be9414d6964cd71019613edff6d88b893
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.65e-05194184729f83cdd63314fff41258937d70b881a5503bfcc
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 NEB MADD CSF2RA SEC16A UNC80 SON

1.65e-0519418470b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 PLEKHA6 OLFML3 NRP2 BMP3 NUAK1 SLC27A3

1.71e-0519518473a0cad69cfc150a27a0666f612f5294c817197d7
ToppCellIPF-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.71e-0519518479c32756edb54f0c211185d9a98073fe01fd1526a
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL6A3 PLEKHA6 OLFML3 NRP2 BMP3 NUAK1 SLC27A3

1.71e-0519518472b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

COL6A3 PDGFRL RGS11 OLFML3 PGR THBS2 HSPB6

1.71e-0519518475870b2956d50d6550a3174a220a6cc70c5538d70
ToppCellIPF-Stromal-Fibroblast|IPF / Disease state, Lineage and Cell class

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.76e-051961847f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.76e-0519618477e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 RIPOR3 UST PGR PXDN C1R

1.76e-051961847a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellControl-Stromal-Fibroblast|Control / Disease state, Lineage and Cell class

COL6A3 PDGFRL DDR2 OLFML3 THBS2 PXDN C1R

1.76e-0519618477ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 RIPOR3 UST PGR PXDN C1R

1.76e-0519618473e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.76e-05196184754aefcebf13704f51de84379e2e22ec0734b9461
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL OLFML3 GSTA4 HSPB6 C1R SOX14

1.76e-051961847988a3e0688e0a7ba69774497d3b130631bb26c50
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL6A3 DDR2 OLFML3 THBS2 PXDN HSPB6 C1R

1.82e-0519718473bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL6A3 DDR2 OLFML3 THBS2 PXDN HSPB6 C1R

1.82e-05197184717344464fdcc5ba0c03959696b97c195f11e644c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL6A3 PDGFRL DDR2 OLFML3 THBS2 HSPB6 C1R

1.82e-051971847c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 DDR2 RIPOR3 UST THBS2 PXDN C1R

1.82e-0519718476d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL6A3 DDR2 OLFML3 THBS2 PXDN HSPB6 C1R

1.82e-0519718475b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL6A3 PDGFRL BCAN OLFML3 THBS2 HSPB6 C1R

1.88e-051981847bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCellControl-Stromal|Control / Disease state, Lineage and Cell class

COL6A3 PDGFRL DDR2 OLFML3 THBS2 PXDN C1R

1.88e-051981847ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
DrugAntimycin A [1397-94-0]; Down 200; 7.2uM; PC3; HT_HG-U133A

CLDN14 GJC1 DAZAP2 PLA2G15 TGFB2 KIAA1549L UBAP2L NIPBL EP300 EPB41L1

3.33e-06193180102098_DN
DrugEtodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A

PDS5B LMF1 TRIOBP MAGEF1 GTF3C5 MADD LSM14B TOR1AIP1 ATPAF2 MPI

4.18e-06198180107006_DN
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.54e-0521762180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

3.54e-0521762cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

3.54e-0521762cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

3.54e-0521762DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

3.54e-0521762cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.54e-0521762C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

3.54e-0521762DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

3.54e-0521762C0035934
Diseasecolon carcinoma (is_marker_for)

FOXA1 TGFB2 KMT2D

5.71e-05131763DOID:1520 (is_marker_for)
Diseasesystemic lupus erythematosus (implicated_via_orthology)

RC3H1 PRDM1 PTPRC EP300

1.26e-04431764DOID:9074 (implicated_via_orthology)
Diseasestomach cancer (is_marker_for)

CDK12 DDR2 FOXA1 KMT2D GSE1 GLDC

2.16e-041421766DOID:10534 (is_marker_for)
DiseaseMalignant neoplasm of breast

MAGEA1 PCDHGB6 RCCD1 DTX3 MSI1 FOXA1 PGR CLASRP HOXA4 NSUN6 KMT2D PTPRC ARFGAP3 ARRDC3 TOR1AIP1 NIPBL EP300

2.52e-04107417617C0006142
DiseaseDiffuse Large B-Cell Lymphoma

CREBBP PRDM1 KMT2D EP300

3.29e-04551764C0079744
DiseaseProstatic Neoplasms

CDK12 PCDH11Y UNC13D FOXA1 CREBBP KMT2D PTPRC BRPF1 HSD3B1 DNASE1L2 ZNF292 TJP3

3.48e-0461617612C0033578
DiseaseMalignant neoplasm of prostate

CDK12 PCDH11Y UNC13D FOXA1 CREBBP KMT2D PTPRC BRPF1 HSD3B1 DNASE1L2 ZNF292 TJP3

3.48e-0461617612C0376358
Diseasefecal incontinence

PLB1 CDH7

3.50e-0451762EFO_0009523
Diseasenephrotic syndrome (biomarker_via_orthology)

NPHS1 NOS1 SOAT2

3.85e-04241763DOID:1184 (biomarker_via_orthology)
DiseaseLeft ventricular mass to end-diastolic volume ratio

LMF1 PXDN PXN

4.36e-04251763EFO_0010556
DiseaseBone Diseases, Developmental

ZIC3 TGFB2 NIPBL

5.49e-04271763C0005941
Diseasearterial stiffness measurement

NPAS3 GSTA4 CLCN6 LSM14B

5.88e-04641764EFO_0004517
Diseasecholesteryl ester 24:4 measurement

SOAT2 SOAT1

7.28e-0471762EFO_0021447
Diseasecongenital heart disease (implicated_via_orthology)

UBE2R2 KMT2D SON MYBPC3

7.82e-04691764DOID:1682 (implicated_via_orthology)
DiseaseCorneal astigmatism

SYT17 MADD BMP3 TNR

1.18e-03771764EFO_1002040
Diseaseelectrocardiography

JCAD LMF1 DDR2 PLEKHA6 UST UBE2R2 CLCN6 CD36 PROB1 MYBPC3

1.37e-0353017610EFO_0004327
Diseasesevere acute respiratory syndrome, COVID-19

COL6A3 SLFN5 REXO1 MAGI2 PXDN GLDC PCDH11X PXN TNR

1.52e-034471769EFO_0000694, MONDO_0100096
Diseasefish oil supplement exposure measurement, triglyceride measurement

MAP1A METAP1

1.54e-03101762EFO_0004530, EFO_0600007
Diseaseleft ventricular structural measurement

THBS2 PXDN CD36 PXN

1.93e-03881764EFO_0008205
Diseasecholesteryl ester 24:5 measurement

SOAT2 SOAT1

2.24e-03121762EFO_0021448
DiseaseNeurobehavioral Manifestations

MAGI2 NOS1

2.24e-03121762C0525041
Diseaseleft ventricular systolic function measurement

PXDN PXN GAREM1

2.31e-03441763EFO_0008206
DiseaseC-reactive protein measurement

MAP1A KCTD8 RIPOR3 ZCCHC2 MADD CLASRP METAP1 PXDN AK5 LPA SEC16A PCDH15 PXN QSER1 SLC27A3 MYBPC3

2.42e-03120617616EFO_0004458
Diseasesalicylurate measurement

LMF1 CHTF18

2.64e-03131762EFO_0010532
DiseaseIGF-1 measurement

LMF1 MAP1A RC3H1 MRPL4 METAP1 LPA PAH SCAI MYBPC3

2.75e-034881769EFO_0004627
DiseaseCeliac Disease

MAGI2 CD36 SOAT2

2.79e-03471763C0007570
Diseaseserum albumin measurement

NPHS1 MAP1A CDK12 ZCCHC2 MADD PRDM1 METAP1 LPA CD36 MYBPC3

3.05e-0359217610EFO_0004535
DiseaseAdenoid Cystic Carcinoma

CREBBP MAGI2 EP300 SON

3.07e-031001764C0010606
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

CLDN14 TRIOBP PCDH15

3.52e-03511763cv:CN043650
DiseaseLymphoma, Follicular, Grade 2

CREBBP KMT2D

3.53e-03151762C1956132
DiseaseLymphoma, Follicular, Grade 3

CREBBP KMT2D

3.53e-03151762C1956131
DiseaseLymphoma, Follicular, Grade 1

CREBBP KMT2D

3.53e-03151762C1956130
DiseaseLymphoma, Large-Cell, Follicular

CREBBP KMT2D

3.53e-03151762C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

CREBBP KMT2D

3.53e-03151762C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

CREBBP KMT2D

3.53e-03151762C0079758
DiseaseHypertriglyceridemia

LMF1 LIPI

3.53e-03151762C0020557
Diseasevision disorder

MAGI2 PXDN

4.02e-03161762MONDO_0021084
DiseaseT-Cell Lymphoma

KMT2D EP300

4.02e-03161762C0079772
DiseaseMammary Carcinoma, Human

PCDHGB6 RCCD1 DTX3 FOXA1 PGR NSUN6 KMT2D ARRDC3 EP300

4.43e-035251769C4704874
DiseaseMammary Neoplasms, Human

PCDHGB6 RCCD1 DTX3 FOXA1 PGR NSUN6 KMT2D ARRDC3 EP300

4.43e-035251769C1257931
Diseaseoral motor function measurement

GSX1 MON1B

4.54e-03171762EFO_0021793
DiseaseMammary Neoplasms

PCDHGB6 RCCD1 DTX3 FOXA1 PGR NSUN6 KMT2D ARRDC3 EP300

4.54e-035271769C1458155
DiseaseEndometrial Neoplasms

PLXNA3 PGR EP300

5.06e-03581763C0014170
DiseaseBreast Carcinoma

PCDHGB6 RCCD1 DTX3 FOXA1 PGR NSUN6 KMT2D ARRDC3 EP300

5.18e-035381769C0678222
DiseaseAntihypertensive use measurement

DDR2 PAQR8 OLFML3 MADD USP38 CACNA1H

5.28e-032651766EFO_0009927
Diseaseasthma

PDS5B COL6A3 ATP6V0A1 CDK12 UNC13D USP10 PTPRC MAVS GLDC ARHGAP27 XRCC6

5.61e-0375117611MONDO_0004979
Diseaseimmature platelet measurement

JCAD DAZAP2 GSE1 CD36

5.71e-031191764EFO_0803541

Protein segments in the cluster

PeptideGeneStartEntry
ERTPDGQYIYRLEPN

CHTF18

806

Q8WVB6
PPPNQRRVYISYLDS

EP300

1386

Q09472
RRLPFPEPYILVYAN

BMP3

231

P12645
RRQSVSPPYKEPSAY

CDK12

271

Q9NYV4
YSDRPTARRKPDYEP

ARFGAP3

396

Q9NP61
YPDSTLPPQREDRFY

CTAGE4

616

Q8IX94
YPDSALPPQREDRFY

CTAGE6

616

Q86UF2
YPDSTLPPQREDRFY

CTAGE8

616

P0CG41
YPDSTLPPQREDRFY

CTAGE9

616

A4FU28
YPDSALPPQREDRFY

CTAGE15

616

A4D2H0
VSFLLRPIYTYRPPF

HSD3B1

301

P14060
RPIYTYRPPFNRHIV

HSD3B1

306

P14060
VPRAPDPAYIYDEFL

GSE1

716

Q14687
YYAGEVRTFPIQEPP

AJM1

326

C9J069
VRTFPIQEPPSRSYY

AJM1

331

C9J069
IQEPPSRSYYGEAPR

AJM1

336

C9J069
VRPGPEFLTRAYTFY

APCDD1L

66

Q8NCL9
CPPPNTRRVYISYLD

CREBBP

1421

Q92793
RTDVAVLRYQPPPEY

AMOTL1

356

Q8IY63
VLRYQPPPEYGVTSR

AMOTL1

361

Q8IY63
YPEVYQERFPTPESA

DEPDC1B

481

Q8WUY9
FEFVRPYSDYLNPRS

CCNT1

681

O60563
PDPARLSPAAYYAQR

AMBRA1

716

Q9C0C7
PRSYPPDLRCNYSIR

C1R

211

P00736
PSFPYSYRYRLDDPD

ATP1B4

11

Q9UN42
YIQEFRYRPPPLYSE

ARRDC2

376

Q8TBH0
AYIQEFRFLPPPLYS

ARRDC3

381

Q96B67
DSRYFDLYDPPPDVS

DENND4A

471

Q7Z401
TQIRPSYLREPPYSR

RC3H1

726

Q5TC82
RAYVSPRAPFYRPLA

RCCD1

141

A6NED2
DIFRIYAPEAPYTSP

PDS5B

86

Q9NTI5
VPTPDSFYYESFPDR

PLA2G15

336

Q8NCC3
TRDYAPPPRDYTYRD

RBMX

231

P38159
RQNPRGTDIYLPYTP

QSER1

1101

Q2KHR3
LRPDETPYRFQTPYF

RGS11

96

O94810
TPERAALPYFPRRYG

OLFML3

356

Q9NRN5
YPTLSEPIRYSIPEE

PCDHGB6

26

Q9Y5F9
EDRLFIRYPPKYSTP

MON1B

516

Q7L1V2
PDVPPEYYSCRFRVN

ANO7

221

Q6IWH7
NEAYRFRVALPAYPA

BCAN

101

Q96GW7
EPYYRSLRDFSPQLP

NPHS1

1136

O60500
VYANPFYRPTTPQRE

PALMD

261

Q9NP74
NPPQFYPREYAASIS

DCHS1

681

Q96JQ0
TDAPPAYSELYRPSF

DAZAP2

36

Q15038
YPPDPAQLTEDITRY

EPB41L1

176

Q9H4G0
RDPDRQPEKYTSRFY

KCTD8

256

Q6ZWB6
FLSVEPRPFDPQYYE

LEO1

381

Q8WVC0
PTRYPLVSVNEAPYR

HSFY1

346

Q96LI6
APYYLRAPSVALPVA

HSPB6

51

O14558
TRPVPSYIQRPDYAD

METAP1

96

P53582
PTPYPDERSFQYADI

MAP1A

1956

P78559
GSVRRRIYDNPYFEP

MADD

761

Q8WXG6
YPLYFARRECSPEPA

MYADML2

106

A6NDP7
YRQVPDSDPARYEFL

MAGEA1

251

P43355
YRQAPGSDPVRYEFL

MAGEA8

261

P43361
YREVPNSSPPRYEFL

MAGEC1

1056

O60732
YLDYRRVPNSNPPEY

MAGED1

616

Q9Y5V3
VYQSYQPRTSDRPPD

MAVS

91

Q7Z434
YRRVPHTNPPEYEFS

MAGEF1

226

Q9HAY2
PPFTDYRQPPLDYRQ

MAGI2

1086

Q86UL8
SPDTRQYPLSDYRQP

MAGI2

1126

Q86UL8
PARAYAPPTERKRFY

ATPAF2

36

Q8N5M1
QEYLELVGRPFFPPY

MGAM2

316

Q2M2H8
ENSNFPYRRYDRLPP

AK5

86

Q9Y6K8
PYRRYDRLPPIHQFS

AK5

91

Q9Y6K8
YDRIFPLRPDYQEPS

DDR2

471

Q16832
SDRPFIPYELYTPAT

JMJD7

201

P0C870
DPLAPDLARYPSYSQ

JMJD7

241

P0C870
PAPPREEIYEYIIFR

LSM14B

56

Q9BX40
PRPVTAYDGFVQYIP

JCAD

411

Q9P266
SPKEYNSPSFRPEYI

C2CD6

506

Q53TS8
RSSFTYYPDPSFEPL

PLXNA3

1116

P51805
ISFPPSYPYSEDARQ

INPP5A

321

Q14642
PNYPDRNLPTIFVYL

PDCL3

156

Q9H2J4
DFLLDPSRSYSYPRQ

GAREM1

641

Q9H706
AAALYQTSYPLPDPR

GSX1

116

Q9H4S2
NTLYPQYDPVYRLDP

NIPBL

1346

Q6KC79
RRFDPIPAQYVRVYP

NRP2

561

O60462
QEYIRQLPPNFPYRD

LAPTM4B

221

Q86VI4
SYRRISPPVDLEYQY

KNTC1

1561

P50748
SVPLPGYIEAYPRSR

KIAA1549L

1756

Q6ZVL6
PLGYPQEEYFDRATP

PCDH11X

1086

Q9BZA7
YRYLPTEQEVRFRPA

FOXRED2

536

Q8IWF2
PVYLSPSFDSVLPRY

NSUN6

201

Q8TEA1
PTRSQEDPYLSIYDP

MPI

326

P34949
APGYTYQFPEFRVER

MSI1

236

O43347
IPRPFSVRYDPYTQR

PAH

406

P00439
TEREYFNRYREVPPP

RBBP6

791

Q7Z6E9
SRYPPFPSDYLALQL

INO80E

136

Q8NBZ0
LNYRLTPSFEYQPDP

NOS1

701

P29475
RPVFLSEETPYSYPT

PXN

21

P49023
QVYPPYLNYLRPDSE

PGR

536

P06401
DVPQLFREPYIRTGY

PAQR8

41

Q8TEZ7
TRSPIEPSALEPAYY

FOXA1

446

P55317
SRVRYRVDDVQFPYP

PCDH15

961

Q96QU1
RPSVYLPTREYPSEQ

DDA1

31

Q9BW61
PQLFGYPDPTYLTRV

DTX3

321

Q8N9I9
TPFLYPTRIPYEESS

HSPBAP1

201

Q96EW2
PPPDEIYVRTVYNIF

GSTA4

206

O15217
ERRYTPYPNLYPDQS

CLCN6

711

P51797
YLYPDPEDVFSREPF

DNASE1L2

116

Q92874
QDEAPYRPYQAPPRA

CLDN14

186

O95500
GYRDPFLSLVPYPVT

CD36

181

P16671
RRELEDPGAYNYPFT

GJC1

266

P36383
EPPYASPRYLRNFTL

EXTL3

581

O43909
RAEPPGPYFYDLTVT

COL6A3

3011

P12111
RNPDPVAAPYCYTRD

LPA

876

P08519
QRSGELSSPEYPRPY

MASP2

191

O00187
RPRYEQAPPRGYVTF

ANKS3

286

Q6ZW76
FPNYCTPPRRSEPIY

KPRP

291

Q5T749
RPAIAINNPYVPRTY

CSN3

66

P07498
PYSLDNPSKPREDFY

ENAM

701

Q9NRM1
EVVSFSPDPLPVRYY

ENGASE

61

Q8NFI3
NPRELIAYSQYPRPS

IDS

456

P22304
RFPRRSYQYNVPESL

CDH7

261

Q9ULB5
RSTFPSPEAQRRPYY

CACNA1H

1586

O95180
SPEAQRRPYYADYSP

CACNA1H

1591

O95180
EPLPEDYYTRPVNLT

DCTN4

226

Q9UJW0
ASYYAPRTAREPAYP

HOXA4

71

Q00056
PRTAREPAYPAAALY

HOXA4

76

Q00056
GPTAPRDVQYFLYIR

CSF2RA

141

P15509
SERRRLYPPSAEYPD

CKMT1A

41

P12532
PLGYPQEEYFDRATP

PCDH11Y

1081

Q9BZA8
PAYFTSPKVPERVYS

HS3ST1

121

O14792
PPQDSPYGRYRFEIA

PHYHIPL

241

Q96FC7
SRPPTDLEYDPLSNY

REXO1

226

Q8N1G1
LFAPTLIYRDSYPRN

SOAT1

301

P35610
RRFPSIVYEDPYQVS

TEX55

486

Q96M34
TRDYAPPPRDYTYRD

RBMXL1

231

Q96E39
YVSKRCTPNDPEPRY

SNTA1

221

Q13424
QDSRYRPLYPFSLPY

MRPL4

276

Q9BYD3
RPLYPFSLPYSDFPR

MRPL4

281

Q9BYD3
PSVLRRTYNPDDYFR

SYT17

141

Q9BSW7
GPRFSRKPPYSRLDY

LIPI

186

Q6XZB0
SLTYPERPPLCRYNI

LIPI

426

Q6XZB0
NVLYGPDLPRIYPSF

PSG6

326

Q00889
PDLPRIYPSFTYYRS

PSG6

331

Q00889
PFYLPAQYVRELPAL

ARHGAP27

56

Q6ZUM4
PLYASPEIVNGRPYR

NUAK1

216

O60285
NYPPNREISRNESPY

NPAS3

666

Q8IXF0
YGIERPTYITRSPIP

PRDM1

316

O75626
RNDELNYPPYFPELT

SI

1411

P14410
NYPPYFPELTKRTDG

SI

1416

P14410
PFLRTPRNSNYTYPI

PLB1

1046

Q6P1J6
PTTYARPEPSIYQNR

ODF3L1

201

Q8IXM7
RPEPSIYQNRSPTYS

ODF3L1

206

Q8IXM7
PSPSYFDVVYLNPDR

PDGFRL

176

Q15198
PESGRYYFVEAPRQP

PROB1

886

E7EW31
LYGSNDPYRREPRSP

STXBP5

671

Q5T5C0
PPRAFVYINEYRVGE

SUV39H1

156

O43463
RYQELRSPSGAEVPY

TRIOBP

36

Q9H2D6
FCPTLIYRETYPRTP

SOAT2

276

O75908
LRPQTRPSVYVAIYP

SH3RF1

441

Q7Z6J0
SVDFPEYPPSSNYIR

STARD6

131

P59095
QDTPDAPPRPTSYYR

BRPF1

186

P55201
RRDSPTYDPYKRSPS

CLASRP

291

Q8N2M8
PYRDYLDVPAPEATT

C15orf39

511

Q6ZRI6
RFYPVYPAPNVVANT

ZCCHC2

1106

Q9C0B9
NAIPPTFYRPYFRIV

TGFB2

116

P61812
APELYRAPFPLYALQ

PREB

6

Q9HCU5
NYPECSNPRLFYIIP

UST

236

Q9Y2C2
ADPYRPVASPRTDPY

ZIC3

196

O60481
SPSRFYPVSRRVPEY

PLEKHA6

336

Q9Y2H5
ALCRYTPRRNIPPYF

XRCC6

396

P12956
LRYLTNEREPYAPGT

ZBTB11

11

O95625
TYVRDIYPFRRSVSP

UNC80

2056

Q8N2C7
PPLRYPRYEATSVQQ

TOR1AIP1

196

Q5JTV8
LQTRFPLDYYSIPFP

UBAP2L

826

Q14157
QNYRYPEPERPSSRA

SEC16A

1211

O15027
PPSTPSFRERYYLSV

RIPOR3

346

Q96MK2
EYKRVPNSRPPEYEF

TRO

591

Q12816
YTHVSENLPPYARPR

SLC27A3

606

Q5K4L6
LRPYFYVGPDSQPLR

TRIM75

446

A6NK02
FRYPRDPYTVEQARA

PXDN

661

Q92626
PPVASFDYYRVSYRP

TNR

886

Q92752
SLEFPTRYSPYRPYR

ZNF292

2101

O60281
RNYPESYPQLPRDET

SCAI

561

Q8N9R8
EAYAPRIFFEASRPP

USP38

501

Q8NB14
PTDRYNSYNRPRPKA

ZC3H4

1211

Q9UPT8
RGYFPRFEEPAPLSY

TJP1

1126

Q07157
APLSYDSRPRYEQAP

TJP1

1136

Q07157
YREINPAPYTIITFP

ATP6V0A1

386

Q93050
SALTRQGRYPPYERV

TJP3

596

O95049
YYPIVVFFIPESRPA

TJP3

691

O95049
RDIRPGAAFEPTYIY

USP10

491

Q14694
PIFSRLDAPVDYFYR

GTF3C5

171

Q9Y5Q8
SVYIFREGALPPYRQ

GTF3C5

391

Q9Y5Q8
IDYPYSPPTFRFLTK

UBE2R2

66

Q712K3
GVPAYRFVRFDYIPP

THBS2

51

P35442
PEIISPTYRPIGRYT

USP2

221

O75604
RYPAPPNVTISRLTY

VSIG10L2

596

P0DP72
PSPLEAEFQRLPSYR

PTPRC

941

P08575
YPLEPRTETYPDRGQ

UNC13D

261

Q70J99
LPPSDTIYSYVRPER

TCF25

586

Q9BQ70
RYFPVFSDRVVYTPE

SLFN5

376

Q08AF3
PDPYRLAQDPYRLAQ

SON

911

P18583
QDPYRLGHDPYRLTP

SON

946

P18583
RYVFPLPYLGDTDPL

SOX14

91

O95416
DRPYSREVAAFPLPF

GLDC

961

P23378
PDIFRPGSYTDPYAQ

KMT2D

2366

O14686
GAYFPPLSLEELRPY

LMF1

541

Q96S06
RQAPPSEYERIAFQY

MYBPC3

326

Q14896
SLFYPYNDSPELRRV

NEB

216

P20929