Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium channel activity

TRPM4 SCN11A HCN4 SCN3A SCN10A

3.66e-0652905GO:0005272
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A HCN4 SCN3A SCN10A

5.35e-0626904GO:0005248
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

ESCO2 SPTLC2 PORCN SATL1 CREBBP GPAT4 EP300 SOAT2

1.21e-05238908GO:0016747
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

2.01e-052902GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

2.01e-052902GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

6.01e-053902GO:0043993
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRB2 GABRG1 GABRA1

6.88e-0518903GO:0022851
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRB2 GABRG1 GABRA1

8.14e-0519903GO:0004890
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

TRPM4 SCN11A SLC12A3 HCN4 SCN3A SCN10A

1.24e-04171906GO:0015081
GeneOntologyMolecularFunctionGABA receptor activity

GABRB2 GABRG1 GABRA1

1.28e-0422903GO:0016917
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GABRB2 GABRG1 TRPM4 SCN11A HCN4 SCN3A PKD1 SCN10A GABRA1

2.25e-04459909GO:0005216
GeneOntologyMolecularFunctionlysine N-acetyltransferase activity, acting on acetyl phosphate as donor

ESCO2 EP300

2.98e-046902GO:0004468
GeneOntologyMolecularFunctionN-acetyltransferase activity

ESCO2 SATL1 CREBBP EP300

4.27e-0478904GO:0008080
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRB2 GABRG1 TRPM4 SCN11A ATP6V1H SLC12A3 HCN4 SCN3A PKD1 SCN10A GABRA1

5.95e-047589011GO:0015318
GeneOntologyMolecularFunctionchannel activity

GABRB2 GABRG1 TRPM4 SCN11A HCN4 SCN3A PKD1 SCN10A GABRA1

5.99e-04525909GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRB2 GABRG1 TRPM4 SCN11A HCN4 SCN3A PKD1 SCN10A GABRA1

6.07e-04526909GO:0022803
GeneOntologyMolecularFunctiontransporter activity

GABRB2 GABRG1 TRPM4 SCN11A SLC35A3 ATP6V1H ABCA4 SLC12A3 HCN4 SCN3A PKD1 SCN10A OSBPL10 APOB GABRA1

6.10e-0412899015GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GABRB2 GABRG1 TRPM4 SCN11A ATP6V1H SLC12A3 HCN4 SCN3A PKD1 SCN10A GABRA1

8.63e-047939011GO:0015075
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRG1 GABRA1

1.08e-0311902GO:0008503
GeneOntologyMolecularFunctionN-acyltransferase activity

ESCO2 SATL1 CREBBP EP300

1.17e-03102904GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

ESCO2 SATL1 CREBBP EP300

1.26e-03104904GO:0016407
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRB2 GABRG1 GABRA1

1.49e-0350903GO:0099095
GeneOntologyMolecularFunctionglycosphingolipid binding

SELP LAMA1

1.52e-0313902GO:0043208
GeneOntologyMolecularFunctionantigen binding

TGFB1 IGKV1-39 IGKV1D-39 IGKV4-1 EP300

1.69e-03190905GO:0003823
GeneOntologyMolecularFunctionpre-mRNA intronic binding

PRPF8 EP300

1.76e-0314902GO:0097157
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRB2 GABRG1 TRPM4 HCN4 GABRA1

1.81e-03193905GO:0015276
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

ESCO2 CREBBP EP300

1.96e-0355903GO:0061733
GeneOntologyMolecularFunctionligand-gated channel activity

GABRB2 GABRG1 TRPM4 HCN4 GABRA1

1.98e-03197905GO:0022834
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

2.03e-0315902GO:0010484
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRB2 GABRG1 TRPM4 SCN11A SLC35A3 ATP6V1H ABCA4 SLC12A3 HCN4 SCN3A PKD1 SCN10A GABRA1

2.37e-0311809013GO:0022857
GeneOntologyMolecularFunctionO-acyltransferase activity

PORCN GPAT4 SOAT2

2.40e-0359903GO:0008374
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRB2 GABRG1 SLC12A3 GABRA1

2.47e-03125904GO:0015108
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

ESCO2 CREBBP EP300

2.52e-0360903GO:0034212
GeneOntologyMolecularFunctionacyltransferase activity

ESCO2 RNF123 CS SPTLC2 PORCN SATL1 CREBBP GPAT4 EP300 SOAT2

2.54e-037759010GO:0016746
GeneOntologyMolecularFunctionmembrane insertase activity

EMC1 EMC2

2.61e-0317902GO:0032977
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRB2 GABRG1 GABRA1

3.16e-0365903GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRB2 GABRG1 GABRA1

3.16e-0365903GO:0022824
GeneOntologyMolecularFunctionGABA receptor binding

GABRG1 MAF1

3.62e-0320902GO:0050811
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

3.99e-0321902GO:0042975
GeneOntologyMolecularFunctiongated channel activity

GABRB2 GABRG1 TRPM4 HCN4 SCN10A GABRA1

4.02e-03334906GO:0022836
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM4 SCN11A HCN4 SCN3A PKD1 SCN10A

4.57e-03343906GO:0005261
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

GABRB2 GABRG1 SLC12A3 GABRA1

4.85e-03151904GO:0008509
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM4 SCN11A SLC12A3 HCN4 SCN3A PKD1 SCN10A

5.04e-03465907GO:0046873
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRB2 GABRG1 GABRA1

5.09e-0377903GO:0005230
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GABRB2 GABRA1

5.20e-0324902GO:0099507
GeneOntologyMolecularFunctionRNA helicase activity

DHX38 DHX57 SNRNP200

5.28e-0378903GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DHX38 DHX57 SNRNP200

5.66e-0380903GO:0008186
GeneOntologyBiologicalProcessmembrane depolarization during action potential

TRPM4 SCN11A HCN4 SCN3A SCN10A

5.06e-0736915GO:0086010
GeneOntologyBiologicalProcessactin-mediated cell contraction

TRPM4 SCN11A HCN4 SCN3A SCN10A ZEB2

2.10e-05127916GO:0070252
GeneOntologyBiologicalProcessmacrophage derived foam cell differentiation

TGFB1 APOB EP300 SOAT2

3.17e-0541914GO:0010742
GeneOntologyBiologicalProcessfoam cell differentiation

TGFB1 APOB EP300 SOAT2

3.84e-0543914GO:0090077
GeneOntologyBiologicalProcesscardiac muscle cell action potential

TRPM4 SCN11A HCN4 SCN3A SCN10A

4.16e-0587915GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

TRPM4 SCN11A HCN4 SCN3A SCN10A

5.73e-0593915GO:0086003
GeneOntologyBiologicalProcessregulation of angiotensin metabolic process

SUCNR1 EP300

5.76e-053912GO:0060177
GeneOntologyBiologicalProcessactin filament-based movement

TRPM4 SCN11A HCN4 SCN3A SCN10A ZEB2

5.99e-05153916GO:0030048
GeneOntologyBiologicalProcessregulation of transcription by RNA polymerase I

MAF1 UBTFL1 CREBBP EIF2AK3

6.99e-0550914GO:0006356
GeneOntologyBiologicalProcesscalcitonin gene-related peptide receptor signaling pathway

SCN11A CALCRL

1.15e-044912GO:1990408
GeneOntologyBiologicalProcessthigmotaxis

SCN11A EP300

1.15e-044912GO:0001966
GeneOntologyBiologicalProcessresponse to high light intensity

SCN11A RDH13

1.15e-044912GO:0009644
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

1.15e-044912GO:0018076
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

EFNA5 NTRK2 BCL11A ZEB2 EP300

1.50e-04114915GO:0050772
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

TRPM4 SCN11A SCN3A SCN10A

1.63e-0462914GO:0086002
GeneOntologyBiologicalProcessmembrane depolarization

TRPM4 SCN11A HCN4 SCN3A SCN10A

1.99e-04121915GO:0051899
GeneOntologyBiologicalProcesssodium ion transport

TGFB1 TRPM4 SCN11A SLC12A3 HCN4 SCN3A SCN10A

2.16e-04275917GO:0006814
GeneOntologyBiologicalProcessaction potential

TRPM4 SCN11A HCN4 NTRK2 SCN3A SCN10A

2.66e-04201916GO:0001508
GeneOntologyBiologicalProcessinhibitory synapse assembly

GABRB2 GABRG1 GABRA1

3.09e-0430913GO:1904862
GeneOntologyBiologicalProcesssodium ion transmembrane transport

TRPM4 SCN11A SLC12A3 HCN4 SCN3A SCN10A

3.20e-04208916GO:0035725
GeneOntologyBiologicalProcessbehavioral response to pain

SCN11A SCN3A SCN10A

3.76e-0432913GO:0048266
GeneOntologyBiologicalProcessbundle of His cell action potential

TRPM4 SCN10A

3.99e-047912GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

TRPM4 SCN10A

3.99e-047912GO:0086028
GeneOntologyBiologicalProcesscellular response to histamine

GABRB2 GABRA1

3.99e-047912GO:0071420
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

TGFB1 IGKV1-39 IGKV1-27 TRPM4 IGKV1-9 IGKV1D-39 SUCNR1 IGKV4-1

4.10e-04403918GO:0002440
GeneOntologyBiologicalProcesstranscription by RNA polymerase I

MAF1 UBTFL1 CREBBP EIF2AK3

4.14e-0479914GO:0006360
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

TRPM4 HCN4 SCN10A

4.50e-0434913GO:0086019
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

CREBBP ZEB2 EP300

4.91e-0435913GO:1903846
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

GABRB2 GABRG1 GABRA1

4.91e-0435913GO:0007214
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

CREBBP ZEB2 EP300

4.91e-0435913GO:0030511
GeneOntologyBiologicalProcesscollateral sprouting

EFNA5 BCL11A ZEB2

5.79e-0437913GO:0048668
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRB2 GABRG1 TRPM4 SCN11A PTPA HCN4 SCN3A PKD1 SCN10A PORCN CATSPERB CATSPERG GABRA1

1.27e-083789313GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

GABRB2 GABRG1 TRPM4 SCN11A PTPA ATP6V1H HCN4 SCN3A PKD1 SCN10A PORCN CATSPERB CATSPERG GABRA1

7.68e-085239314GO:1902495
GeneOntologyCellularComponenttransporter complex

GABRB2 GABRG1 TRPM4 SCN11A PTPA ATP6V1H HCN4 SCN3A PKD1 SCN10A PORCN CATSPERB CATSPERG GABRA1

1.42e-075509314GO:1990351
GeneOntologyCellularComponentcation channel complex

TRPM4 SCN11A PTPA HCN4 SCN3A PKD1 SCN10A CATSPERB CATSPERG

1.04e-06235939GO:0034703
GeneOntologyCellularComponentsodium channel complex

TRPM4 SCN11A SCN3A SCN10A

8.01e-0629934GO:0034706
GeneOntologyCellularComponentmembrane protein complex

GABRB2 GABRG1 TRPM4 TRAV7 SCN11A PTPA ATP6V1H EMC1 HCN4 SCN3A PKD1 SCN10A PORCN CATSPERB C7 CALCRL EMC2 CATSPERG GABRA1

2.75e-0514989319GO:0098796
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN3A SCN10A

5.54e-0517933GO:0001518
GeneOntologyCellularComponentGABA-A receptor complex

GABRB2 GABRG1 GABRA1

7.84e-0519933GO:1902711
GeneOntologyCellularComponentGABA receptor complex

GABRB2 GABRG1 GABRA1

1.07e-0421933GO:1902710
GeneOntologyCellularComponentC-fiber

SCN11A SCN10A

1.17e-044932GO:0044299
GeneOntologyCellularComponentcalcium channel complex

PTPA PKD1 CATSPERB CATSPERG

3.16e-0473934GO:0034704
GeneOntologyCellularComponentEMC complex

EMC1 EMC2

8.61e-0410932GO:0072546
GeneOntologyCellularComponentimmunoglobulin complex

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

8.80e-04166935GO:0019814
GeneOntologyCellularComponentU2-type catalytic step 1 spliceosome

PRPF8 SNRNP200

1.72e-0314932GO:0071006
GeneOntologyCellularComponentcatalytic step 1 spliceosome

PRPF8 SNRNP200

1.72e-0314932GO:0071012
GeneOntologyCellularComponentCatSper complex

CATSPERB CATSPERG

1.98e-0315932GO:0036128
GeneOntologyCellularComponentchloride channel complex

GABRB2 GABRG1 GABRA1

2.10e-0357933GO:0034707
GeneOntologyCellularComponentplasma membrane protein complex

TRAV7 SCN11A HCN4 SCN3A SCN10A PORCN CATSPERB C7 CALCRL CATSPERG

2.56e-037859310GO:0098797
DomainNa_channel_asu

SCN11A SCN3A SCN10A

1.23e-0510893IPR001696
DomainNa_trans_assoc

SCN11A SCN3A SCN10A

1.23e-0510893IPR010526
DomainNa_trans_assoc

SCN11A SCN3A SCN10A

1.23e-0510893PF06512
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

2.25e-052892IPR014744
DomainZnF_TAZ

CREBBP EP300

2.25e-052892SM00551
Domain-

CREBBP EP300

2.25e-0528921.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

2.25e-052892IPR010303
Domain-

CREBBP EP300

2.25e-0528921.10.1630.10
DomainCreb_binding

CREBBP EP300

2.25e-052892PF09030
Domainzf-TAZ

CREBBP EP300

2.25e-052892PF02135
DomainZF_TAZ

CREBBP EP300

2.25e-052892PS50134
DomainKAT11

CREBBP EP300

2.25e-052892SM01250
DomainZnf_TAZ

CREBBP EP300

2.25e-052892IPR000197
DomainKIX

CREBBP EP300

2.25e-052892PF02172
DomainHAT_KAT11

CREBBP EP300

2.25e-052892PF08214
DomainKIX

CREBBP EP300

2.25e-052892PS50952
DomainCBP_P300_HAT

CREBBP EP300

2.25e-052892IPR031162
DomainDUF902

CREBBP EP300

2.25e-052892PF06001
Domain-

CREBBP EP300

2.25e-0528921.10.246.20
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

2.25e-052892IPR013178
DomainKIX_dom

CREBBP EP300

2.25e-052892IPR003101
DomainCBP_P300_HAT

CREBBP EP300

2.25e-052892PS51727
DomainEGF-like_dom

SELP HHIP SUSD1 LAMA1 TENM1 ADAM30 C7 TENM2

2.48e-05249898IPR000742
DomainEGF_1

SELP HHIP SUSD1 LAMA1 TENM1 ADAM30 C7 TENM2

2.94e-05255898PS00022
DomainEGF-like_CS

SELP HHIP SUSD1 LAMA1 TENM1 ADAM30 C7 TENM2

3.47e-05261898IPR013032
Domain-

HHIP TENM1 ROS1 TENM2

3.49e-05398942.120.10.30
DomainEGF_2

SELP HHIP SUSD1 LAMA1 TENM1 ADAM30 C7 TENM2

3.87e-05265898PS01186
Domain6-blade_b-propeller_TolB-like

HHIP TENM1 ROS1 TENM2

6.75e-0546894IPR011042
DomainSushi

SELP SUSD1 C7 CSMD3

1.10e-0452894PF00084
DomainCCP

SELP SUSD1 C7 CSMD3

1.27e-0454894SM00032
DomainEGF_3

SELP HHIP SUSD1 TENM1 ADAM30 C7 TENM2

1.31e-04235897PS50026
DomainTox-GHH_dom

TENM1 TENM2

1.34e-044892IPR028916
DomainTox-GHH

TENM1 TENM2

1.34e-044892PF15636
DomainTen_N

TENM1 TENM2

1.34e-044892IPR009471
DomainTen_N

TENM1 TENM2

1.34e-044892PF06484
DomainTENEURIN_N

TENM1 TENM2

1.34e-044892PS51361
DomainSUSHI

SELP SUSD1 C7 CSMD3

1.46e-0456894PS50923
DomainSushi_SCR_CCP_dom

SELP SUSD1 C7 CSMD3

1.57e-0457894IPR000436
DomainGABAA/Glycine_rcpt

GABRB2 GABRG1 GABRA1

1.73e-0423893IPR006028
DomainIon_trans_dom

TRPM4 SCN11A HCN4 SCN3A SCN10A

2.14e-04114895IPR005821
DomainIon_trans

TRPM4 SCN11A HCN4 SCN3A SCN10A

2.14e-04114895PF00520
DomainYD

TENM1 TENM2

2.22e-045892IPR006530
DomainNuc_rcpt_coact

CREBBP EP300

3.33e-046892IPR009110
Domain-

EMC1 EIF2AK3

3.33e-0468922.140.10.10
DomainQuinoprotein_ADH-like_fam

EMC1 EIF2AK3

3.33e-046892IPR027295
DomainEGF

SELP HHIP SUSD1 LAMA1 TENM1 TENM2

9.06e-04235896SM00181
DomainMBOAT

PORCN SOAT2

1.20e-0311892PF03062
DomainMBOAT_fam

PORCN SOAT2

1.20e-0311892IPR004299
DomainTyr_kinase_rcpt_2_CS

NTRK2 ROS1

1.20e-0311892IPR002011
DomainNeurotransmitter_ion_chnl_CS

GABRB2 GABRG1 GABRA1

1.28e-0345893IPR018000
DomainNeur_chan_memb

GABRB2 GABRG1 GABRA1

1.37e-0346893PF02932
DomainRWD-domain

DHX57 WDR59

1.44e-0312892IPR006575
DomainRECEPTOR_TYR_KIN_II

NTRK2 ROS1

1.44e-0312892PS00239
DomainNeurotrans-gated_channel_TM

GABRB2 GABRG1 GABRA1

1.46e-0347893IPR006029
Domain-

GABRB2 GABRG1 GABRA1

1.46e-03478932.70.170.10
DomainNeur_chan_LBD

GABRB2 GABRG1 GABRA1

1.46e-0347893PF02931
DomainNEUROTR_ION_CHANNEL

GABRB2 GABRG1 GABRA1

1.46e-0347893PS00236
DomainNeur_channel

GABRB2 GABRG1 GABRA1

1.46e-0347893IPR006201
DomainNeur_chan_lig-bd

GABRB2 GABRG1 GABRA1

1.46e-0347893IPR006202
DomainNHL

TENM1 TENM2

1.69e-0313892PS51125
DomainQuinoprotein_ADH-like_supfam

EMC1 WDR36 EIF2AK3

2.06e-0353893IPR011047
DomainChannel_four-helix_dom

SCN11A SCN3A SCN10A

2.54e-0357893IPR027359
Domain-

SCN11A SCN3A SCN10A

2.54e-03578931.20.120.350
DomainDUF1605

DHX38 DHX57

2.91e-0317892IPR011709
DomainOB_NTP_bind

DHX38 DHX57

2.91e-0317892PF07717
DomainZF_ZZ_2

CREBBP EP300

3.27e-0318892PS50135
DomainZF_ZZ_1

CREBBP EP300

3.27e-0318892PS01357
DomainZZ

CREBBP EP300

3.27e-0318892PF00569
DomainHA2

DHX38 DHX57

3.27e-0318892SM00847
DomainHA2

DHX38 DHX57

3.27e-0318892PF04408
DomainHelicase-assoc_dom

DHX38 DHX57

3.27e-0318892IPR007502
DomainZnf_ZZ

CREBBP EP300

3.64e-0319892IPR000433
DomainZnF_ZZ

CREBBP EP300

3.64e-0319892SM00291
PathwayWP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION

GABRB2 GABRG1 NTRK2 GABRA1

4.76e-0538754M39854
PathwayBIOCARTA_TGFB_PATHWAY

TGFB1 CREBBP EP300

9.32e-0517753MM1509
PathwayBIOCARTA_TGFB_PATHWAY

TGFB1 CREBBP EP300

1.32e-0419753M18933
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGKV1-39 AMBP APOB IGKV1D-39 IGKV4-1

1.72e-0498755M27152
PathwayWP_TGFBETA_SIGNALING_PATHWAY

TGFB1 CREBBP ZEB2 EP300

1.78e-0453754MM15880
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

TGFB1 CREBBP ZEB2 EP300

2.05e-0455754M39351
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

TGFB1 CREBBP ZEB2 EP300

2.70e-0459754M39886
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

2.76e-045752MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

2.76e-045752M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

2.76e-045752M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

2.76e-045752M27228
PathwayWP_WNTBETACATENIN_SIGNALING_INHIBITORS_IN_CURRENT_AND_PAST_CLINICAL_TRIALS

PORCN CREBBP

2.76e-045752M48304
PathwayREACTOME_FERTILIZATION

ADAM30 CATSPERB CATSPERG

3.44e-0426753M26922
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

4.13e-046752M22062
PathwayREACTOME_RUNX3_REGULATES_P14_ARF

TGFB1 EP300

4.13e-046752MM15545
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGKV1-39 AMBP IGKV1D-39 IGKV4-1

4.92e-0469754M27150
PathwayREACTOME_REPRODUCTION

ADAM30 CATSPERB CATSPERG

5.30e-0430753MM17211
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

TGFB1 IGKV1-39 SELP APOB IGKV1D-39 IGKV4-1

5.76e-04194756M16312
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

5.76e-047752MM1573
PathwayWP_GABA_RECEPTOR_SIGNALING

GABRB2 GABRG1 GABRA1

5.84e-0431753M39369
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN3A SCN10A

5.84e-0431753M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN3A SCN10A

6.42e-0432753M27455
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

7.66e-048752M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

7.66e-048752M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

7.66e-048752M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

7.66e-048752M46443
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

TGFB1 CREBBP EP300

7.69e-0434753M39771
PathwayREACTOME_SPERM_MOTILITY_AND_TAXES

CATSPERB CATSPERG

9.81e-049752M26935
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

9.81e-049752M47451
PathwayREACTOME_SPERM_MOTILITY_AND_TAXES

CATSPERB CATSPERG

9.81e-049752MM14548
PathwayREACTOME_RUNX3_REGULATES_P14_ARF

TGFB1 EP300

1.22e-0310752M27824
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

1.22e-0310752M27945
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.49e-0311752MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

1.49e-0311752M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

1.49e-0311752M26924
PathwayPID_HNF3A_PATHWAY

APOB CREBBP EP300

1.64e-0344753M285
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

1.78e-0312752M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

1.78e-0312752M27765
PathwayREACTOME_ALK_MUTANTS_BIND_TKIS

BCL11A EIF2AK3

1.78e-0312752M42522
Pubmed

Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome.

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

2.05e-092095510427970
Pubmed

Amino acid sequence of the variable region of M149 mouse myeloma light chain: comparison with the nucleotide sequence of K2 and K3 clones.

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39

1.70e-08119546795447
Pubmed

Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis.

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39

1.70e-0811954279004
Pubmed

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39

1.70e-08119546767723
Pubmed

Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development.

LYZ CREBBP EP300

1.97e-08395316428436
Pubmed

Inhibition of CBP/β-catenin signaling ameliorated fibrosis in cholestatic liver disease.

LYZ CREBBP EP300

1.97e-08395335855613
Pubmed

Human myeloperoxidase in innate and acquired immunity.

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39

1.55e-071895420399194
Pubmed

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins.

CREBBP ZEB2 EP300

1.97e-07595312743039
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

LAMA1 TENM1 CSMD3 GABRA1

3.68e-072295435245678
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN11A SCN3A SCN10A

3.93e-07695323711479
Pubmed

theta, a novel gamma-aminobutyric acid type A receptor subunit.

GABRB2 GABRG1 GABRA1

6.86e-07795310449790
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN11A SCN3A SCN10A

6.86e-07795324440715
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM1 TENM2 GABRA1

1.09e-06895310331952
Pubmed

Significant determinants of mouse pain behaviour.

SCN11A SCN3A SCN10A

1.09e-06895325101983
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN3A SCN10A

1.64e-06995316382098
Pubmed

Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.

GABRB2 GABRG1 GABRA1

2.34e-061095320583128
Pubmed

Nonsyndromic Retinitis Pigmentosa Overview

ABCA4 EMC1 DHX38 PRPF8 SNRNP200

2.97e-068195520301590
Pubmed

The biochemical anatomy of cortical inhibitory synapses.

GABRB2 GABRG1 GABRA1

7.03e-061495322768092
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

7.38e-06295227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

7.38e-06295234845315
Pubmed

GABAAα1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection.

GABRG1 GABRA1

7.38e-06295225348603
Pubmed

Chondroitin sulfate proteoglycans down-regulate spine formation in cortical neurons by targeting tropomyosin-related kinase B (TrkB) protein.

PTPA NTRK2

7.38e-06295222389491
Pubmed

Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis.

TGFB1 LYZ

7.38e-06295232161098
Pubmed

Heat-resistant action potentials require TTX-resistant sodium channels NaV1.8 and NaV1.9.

SCN11A SCN10A

7.38e-06295229970412
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

7.38e-06295219729597
Pubmed

Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas.

SCN11A SCN10A

7.38e-06295224144460
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

7.38e-06295239287984
Pubmed

A state-dependent salt-bridge interaction exists across the β/α intersubunit interface of the GABAA receptor.

GABRB2 GABRA1

7.38e-06295221209255
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

7.38e-06295220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

7.38e-06295225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

7.38e-06295211559821
Pubmed

Prevention of renal apoB retention is protective against diabetic nephropathy: role of TGF-β inhibition.

TGFB1 APOB

7.38e-06295228912302
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

7.38e-06295232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

7.38e-06295219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

7.38e-06295224522976
Pubmed

Phage display of a human antibody against Clostridium tetani toxin.

IGKV1-39 IGKV1D-39

7.38e-0629527926831
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

7.38e-06295221847097
Pubmed

Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves.

SCN11A SCN10A

7.38e-06295228450535
Pubmed

Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.

GABRB2 GABRA1

7.38e-06295211331371
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

7.38e-06295234813504
Pubmed

Lysophosphatidic acid activates TGFBIp expression in human corneal fibroblasts through a TGF-β1-dependent pathway.

TGFB1 TGFBI

7.38e-06295222374302
Pubmed

BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells.

TGFB1 ZEB2

7.38e-06295223352789
Pubmed

Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2.

TGFB1 TGFBI

7.38e-06295226197481
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

7.38e-06295220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

7.38e-06295224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

7.38e-06295237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

7.38e-06295211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

7.38e-06295210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

7.38e-06295235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

7.38e-06295231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

7.38e-06295230888860
Pubmed

Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache.

SCN11A SCN10A

7.38e-06295231534133
Pubmed

Variability in clinical phenotypes of PRPF8-linked autosomal dominant retinitis pigmentosa correlates with differential PRPF8/SNRNP200 interactions.

PRPF8 SNRNP200

7.38e-06295229087248
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

7.38e-06295227881443
Pubmed

TGFBI gene mutations causing lattice and granular corneal dystrophies in Indian patients.

TGFB1 TGFBI

7.38e-06295215623763
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

7.38e-06295219272189
Pubmed

Induction and expression of betaig-h3 in pancreatic cancer cells.

TGFB1 TGFBI

7.38e-06295212379307
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

7.38e-06295232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

7.38e-06295230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

7.38e-06295221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

7.38e-0629529811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

7.38e-06295224089570
Pubmed

Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs.

GABRB2 GABRA1

7.38e-06295212490572
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

7.38e-06295215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

7.38e-06295239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

7.38e-06295222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

7.38e-06295234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

7.38e-06295234019788
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

7.38e-06295215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

7.38e-06295229460469
Pubmed

Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina.

SCN11A SCN10A

7.38e-06295218399542
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

7.38e-06295224551300
Pubmed

TGFBI deficiency predisposes mice to spontaneous tumor development.

TGFB1 TGFBI

7.38e-06295219117985
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

7.38e-06295233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

7.38e-0629529018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

7.38e-06295224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

7.38e-06295230135524
Pubmed

A GABAergic system in atrioventricular node pacemaker cells controls electrical conduction between the atria and ventricles.

GABRB2 HCN4

7.38e-06295238849501
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

7.38e-06295216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

7.38e-06295229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

7.38e-06295210049825
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

7.38e-06295231400758
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

7.38e-06295227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

7.38e-06295229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

7.38e-06295221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

7.38e-06295212646247
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

7.38e-06295211867645
Pubmed

Macrophage-specific de Novo Synthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity.

SPTLC2 LYZ

7.38e-06295226438821
Pubmed

PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects.

PRPF8 SNRNP200

7.38e-06295238605034
Pubmed

Mutation analysis of the TGFBI gene in Vietnamese with granular and Avellino corneal dystrophy.

TGFB1 TGFBI

7.38e-06295214767644
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

7.38e-06295211963968
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

7.38e-06295237450367
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

7.38e-0629529528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

7.38e-06295212696060
Pubmed

Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice.

SCN11A SCN10A

7.38e-06295219931571
Pubmed

Contributions of NaV1.8 and NaV1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons.

SCN11A SCN10A

7.38e-06295234930944
Pubmed

Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice.

SCN11A SCN10A

7.38e-06295216857712
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

7.38e-06295236109165
Pubmed

An R124C mutation in TGFBI caused lattice corneal dystrophy type I with a variable phenotype in three Chinese families.

TGFB1 TGFBI

7.38e-06295218615206
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

7.38e-06295212242694
Cytoband2p12

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 EIF2AK3 IGKV4-1

1.85e-071179662p12
CytobandEnsembl 112 genes in cytogenetic band chr2p11

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 EIF2AK3 IGKV4-1

6.09e-06213966chr2p11
Cytoband5q34

GABRB2 TENM2 GABRA1

4.21e-05329635q34
Cytoband9q33.3

GARNL3 NR6A1 SCAI

6.54e-05379639q33.3
CytobandEnsembl 112 genes in cytogenetic band chr5q34

GABRB2 TENM2 GABRA1

8.92e-0541963chr5q34
Cytoband3p22.2

SCN11A SCN10A

1.16e-03249623p22.2
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN3A SCN10A

4.02e-0696731203
GeneFamilyImmunoglobulin kappa locus at 2p11.2

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

1.39e-0583675351
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRB2 GABRG1 GABRA1

4.52e-0519673563
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELP SUSD1 C7 CSMD3

5.87e-05576741179
GeneFamilyCation channels sperm associated

CATSPERB CATSPERG

2.81e-047672186
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

7.28e-0411672559
GeneFamilyDEAH-box helicases

DHX38 DHX57

1.57e-0316672500
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.77e-0317672486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

1.99e-031867291
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK2 ROS1

9.64e-0340672321
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELP PKD1

1.01e-02416721298
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

HHIP SLC35A3 SERPINI1 EFNA5 NTRK2 SCN3A TENM1 BCL11A IDE CALCRL CSMD3 CREBBP TENM2 GABRA1

8.46e-068189014DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

HHIP SLC35A3 SERPINI1 NTRK2 SCN3A TENM1 BCL11A CALCRL CSMD3 TENM2

1.33e-054279010DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 EFNA5 NTRK2 SCN3A PKD1 CSMD3 TENM2 GABRA1

1.16e-08198968c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellMild-Lymphoid-B|Mild / Condition, Lineage, Cell class and cell subclass

IGKV1-39 IGKV1-27 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

1.44e-071839679b64d2d143525e6f48a191facfd101462ff36324
ToppCellMild-Lymphoid-B-|Mild / Condition, Lineage, Cell class and cell subclass

IGKV1-39 IGKV1-27 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

1.44e-07183967b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ABCA4 LAMA1 TENM1 ROS1 APOB CSMD3

1.50e-071849672cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ABCA4 LAMA1 TENM1 ROS1 APOB CSMD3

1.50e-07184967ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ABCA4 LAMA1 TENM1 ROS1 APOB CSMD3

1.50e-071849672b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

TGFBI MRC1 SUCNR1 RAB20 LYZ MMP19 ZEB2

1.73e-07188967e83de94a9b47a6a90e98face887eae031a322af6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 SCN3A PKD1 CSMD3 TENM2 SCAI GABRA1

2.30e-07196967676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFB1 TGFBI MRC1 SUCNR1 RAB20 LYZ ZEB2

2.38e-071979671ded28732ea5d1f9ebca0b136575103540600ff1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 EFNA5 NTRK2 CSMD3 TENM2 SCAI GABRA1

2.46e-071989678ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellControl-Control-Lymphocyte-B-Plasmablast|Control / Disease, condition lineage and cell class

IGKV1-39 IGKV1-27 IGKV1-9 OSBPL10 IGKV1D-39 EIF2AK3 IGKV4-1

2.55e-07199967c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

GABRB2 SCN3A PKD1 CSMD3 TENM2 SCAI GABRA1

2.63e-0720096748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellBasal_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

GABRB2 FBXW10B APOB BCL11A TENM2 GABRA1

1.46e-06163966679e25e5548d157d49a73057a3b5617dccda260f
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

2.68e-06181966700adfb41e4e377530f0dd31be89e12f109f3469
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

2.85e-06183966dea119e2988e954475f557f0bbe12556a83e81a4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-39 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

2.95e-061849663f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-39 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

2.95e-0618496664bede8db709fd32f40c03265b96f0b12155bb8a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-39 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

3.04e-06185966609080adb2cfb105bb7b8efb617553833299f371
ToppCellMild_COVID-19-B_cell-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-39 IGKV1-9 SCN3A BCL11A IGKV1D-39 IGKV4-1

3.13e-06186966855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

3.23e-06187966cbe25fb3fc8ed6245dc767c884c298c89a774cce
ToppCellNS-critical-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGFBI MRC1 ROS1 LYZ MMP19 ZEB2

3.54e-061909664fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 EIF2AK3 IGKV4-1

3.54e-0619096679ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 EIF2AK3 IGKV4-1

3.54e-0619096618762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell5'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1 IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

3.65e-06191966d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell10x5'-Liver-Myeloid_Dendritic|Liver / Manually curated celltypes from each tissue

TGFBI MRC1 SLC12A3 BCL11A CALCRL LYZ

3.99e-06194966e6391bc7073831847c469ef0b0c437118e1f151f
ToppCellIPF-Myeloid|IPF / Disease state, Lineage and Cell class

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.11e-06195966fdeb958aeaa00f3fc25c4e59efbbc6f4a572c9ce
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 EFNA5 CSMD3 TENM2 SCAI GABRA1

4.11e-061959662e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-27 IGKV1-9 BCL11A IGKV1D-39 IGKV4-1

4.36e-061979669fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGFBI MRC1 LYZ MMP19 SOAT2

4.46e-061129659801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 EFNA5 SCN3A CSMD3 TENM2 GABRA1

4.49e-061989666d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBI MRC1 SPTLC2 LYZ CREBBP ZEB2

4.49e-061989662e470249edc7cf85bed550795ff84cbef22895c0
ToppCellmoderate-Myeloid-Non-resident_Macrophage|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.62e-06199966614c1e788d89310e78984241977941beed8d12dc
ToppCellTransverse-Macrophage-Macrophage|Transverse / Region, Cell class and subclass

TGFBI MRC1 SUCNR1 RAB20 LYZ MMP19

4.76e-0620096617548806ba38008050244151d1216c69ef8a8310
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.76e-062009664657d18e92abde7f0b8b7e4fc9fa0081efe20a55
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.76e-0620096635bbd3fc96c4f249bd79c4c5ad8ee6eb6df32c33
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFB1 TGFBI MRC1 LYZ MMP19 ZEB2

4.76e-0620096626df6ac63710655604888c3be6509b6c4befc0be
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.76e-06200966f1255d4de08134bd0a95296c8cc743e90044d2ff
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.76e-06200966c30da72c3581d384b76c95f5989e32a36d783ef3
ToppCellTransverse-(6)_Macrophage-(60)_Macrophage|Transverse / shred on region, Cell_type, and subtype

TGFBI MRC1 SUCNR1 RAB20 LYZ MMP19

4.76e-062009662be675684a2958ea609939bb45248bede78a26bc
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TGFB1 TGFBI MRC1 LYZ MMP19 ZEB2

4.76e-0620096607819a90ac347883b78d0bb3cd8c5eb0d66e1e22
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TGFBI MRC1 RAB20 LYZ MMP19 ZEB2

4.76e-0620096609bac15df511687ff336c1e7a67d980c6c281f79
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG1 SCN10A TENM1 ROS1 CSMD3

1.57e-0514596596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBI HHIP SLC12A3 SUSD1 SCN3A

1.62e-05146965bee5074c29b132180d35f57d307e342efa9b8cd1
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|368C / Donor, Lineage, Cell class and subclass (all cells)

GABRB2 TGFBI MRC1 SUCNR1 LYZ

2.37e-05158965f9cfb110342be3c91aba9914805332f22ba89101
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

IGKV1-27 IGKV1-9 SERPINI1 IGKV1D-39 IGKV4-1

2.44e-05159965204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GABRG1 SCN10A TENM1 ROS1 CSMD3

2.67e-05162965bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GABRB2 EFNA5 PTCHD3 SCN10A GABRA1

3.00e-05166965545f6c91102568791443717e522f89cb3bd1a070
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1 CSMD3 BBS12 SNRNP200 SOAT2

3.00e-0516696513027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1 CSMD3 BBS12 SNRNP200 SOAT2

3.00e-05166965b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCelltumor_Lung-B_lymphocytes-Plasma_cells|tumor_Lung / Location, Cell class and cell subclass

IGKV1-27 IGKV1-9 SERPINI1 IGKV1D-39 IGKV4-1

3.27e-05169965b36b7632ce55fc7b6b8b66020563d360b3de6fd7
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-9 BCL11A IGKV1D-39 IGKV4-1

3.36e-05170965ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-9 BCL11A IGKV1D-39 IGKV4-1

3.36e-05170965d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-39 IGKV1-9 BCL11A IGKV1D-39 IGKV4-1

3.36e-0517096552787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_monocytic-non-classical_monocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MRC1 NTRK2 CALCRL RAB20 MMP19

3.55e-05172965968d18ab8c3cdeb7936a2aa721a7f41525763863
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 EFNA5 SCN3A CATSPERB CALCRL

3.65e-051739657dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellCTRL-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

TGFBI RNF123 SLC12A3 CALCRL SUCNR1

3.76e-05174965ff4315e9fad198cc323fc987deb8652da137cf98
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

3.86e-05175965d73ee324479172501481b54967a0f3bd870fcf3a
ToppCellmetastatic_Brain-B_lymphocytes-MALT_B_cells|metastatic_Brain / Location, Cell class and cell subclass

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

3.97e-0517696550e207403d48ce1b55a78897adb5519a2430a626
ToppCellNasal_Brush-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

TGFB1 AMBP TENM1 SUCNR1 CSMD3

3.97e-051769655daaba0853afe7d20d4635169ccd4f96e735b938
ToppCellNS-moderate-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TGFBI BCL11A CALCRL TINCR ZEB2

4.07e-05177965de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

MRC1 EFNA5 SCN3A CATSPERB CALCRL

4.30e-05179965411620201a860716a8773b92f50f7b94ef34a586
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-39 OSBPL10 BCL11A IGKV1D-39 IGKV4-1

4.53e-05181965768d14c452192f92fa557ae59e84c43436f575f0
ToppCellLeuk-UTI-Lymphocyte-B-B_memory|Leuk-UTI / Disease, Lineage and Cell Type

IGKV1-27 SCN3A OSBPL10 BCL11A IGKV4-1

4.77e-05183965f7a5daec3e8484c7071164a09e9c961fe64d9f81
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI NTRK2 C7 MMP19 ZEB2

4.77e-051839655cfcd589a480e67654d3d94e71916f122150db10
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI NTRK2 C7 MMP19 ZEB2

4.77e-05183965c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI NTRK2 C7 MMP19 ZEB2

4.77e-0518396581003ddc24164959dd41bb12fcac72638789b8f2
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBI MRC1 LYZ MMP19 ZEB2

4.90e-05184965ba260f8a2e6e510141a6b9c458eb0040acff0352
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

4.90e-051849656f70d8f8ab8362d51f8a58735d42223e06566397
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

5.03e-051859650fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

5.03e-0518596579edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell10x5'-Liver-Myeloid_Dendritic-DC2|Liver / Manually curated celltypes from each tissue

TGFBI MRC1 SLC12A3 RAB20 LYZ

5.16e-0518696592ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGKV1-27 IGKV1-9 IGKV1D-39 EIF2AK3 IGKV4-1

5.16e-05186965e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBI MRC1 RAB20 LYZ MMP19

5.29e-0518796500930e407beaa337f72533a69f32d150faad8b9a
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TGFBI MRC1 CALCRL LYZ MMP19

5.43e-05188965fbf176b48b89c234e4e1e64739afc836bed78a96
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-39 OSBPL10 BCL11A IGKV1D-39 IGKV4-1

5.43e-05188965c3cae529fdbeb233d2b32bcc3537a8aba26a7dc2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SCN3A BCL11A TENM2 ZEB2

5.56e-059696456e993d37b7958abe56682422536045550e29b41
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

TGFBI SLC12A3 SUSD1 BCL11A ARSI

5.56e-051899656c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TGFBI MRC1 LYZ MMP19 ZEB2

5.56e-051899652aebea7a6c2f83112d7c504b742f2c04b92e459a
ToppCell10x5'-Liver-Lymphocytic_B|Liver / Manually curated celltypes from each tissue

IGKV1-39 SCN3A OSBPL10 BCL11A EIF2AK3

5.56e-051899651ebff8185060d78f27f8d887e9adaa5f8faf2196
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EFNA5 SLC12A3 SCN3A LAMA1 NR6A1

5.56e-05189965975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFBI MRC1 LYZ MMP19 ZEB2

5.56e-05189965984b5f21e84dd8273d8437ac2a5a9de4e9484b9a
ToppCellBronchial_Brush-Immune-Luminal_Macrophages|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

TGFBI MRC1 SUCNR1 MMP19 ZEB2

5.85e-0519196588cb6f828407845918c946f8cee5f940cb81800a
ToppCellhematopoetic_progenitors-CD34+_CLP|World / Lineage and Cell class

HHIP SCN3A BCL11A SUCNR1 SCAI

5.85e-0519196532f2537c97c9984629d61c6f34a337f555146ad4
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MRC1 EFNA5 SCN3A CATSPERB CALCRL

5.99e-05192965cbe57cda44232b183821ac633b60a2668265e616
ToppCellCOVID-19-Lymphoid-Plasma,_B_cells|COVID-19 / Condition, Lineage and Cell class

IGKV1-39 IGKV1-9 IGKV1D-39 EIF2AK3 IGKV4-1

6.14e-05193965bffd97a73365e1dd23ff3b0320b4860f04ec091a
ToppCellCOPD-Myeloid|COPD / Disease state, Lineage and Cell class

MRC1 RAB20 LYZ MMP19 ZEB2

6.14e-05193965f58552e286aa27e592497ad78776f58f8ee09841
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

TGFBI MRC1 SPTLC2 RAB20 ZEB2

6.14e-051939655fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellMacrophages-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TGFBI MRC1 LYZ MMP19 ZEB2

6.14e-05193965642f8f20e5a35a4b5d1fc8d3f1e3b9b83a37a654
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 TGFBI MRC1 SUCNR1 ZEB2

6.30e-0519496548c37251518f96524807b5bd1bbc2820637666ad
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-39 IGKV1-27 IGKV1-9 IGKV1D-39 IGKV4-1

6.30e-051949656ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 TGFBI MRC1 SUCNR1 ZEB2

6.30e-051949657b6a34d1f8922b71dcc931421666c1822cec8345
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBI MRC1 LYZ MMP19 ZEB2

6.30e-05194965abce1e824ce2512741c313a5ec336d12f580b093
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBI MRC1 LYZ MMP19 ZEB2

6.30e-051949656810586080cc893e3270b9c8bee2d95ed78e2893
ToppCell(4)_Endothelial_cells-(4)_Lymph_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TGFBI MRC1 ABCA4 EFNA5 SCN3A

6.30e-051949659735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 TGFBI MRC1 SUCNR1 ZEB2

6.30e-05194965435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell(2)_Mono_macro|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TGFBI MRC1 RAB20 LYZ ZEB2

6.30e-051949657c05525614ee8cdfcbf22cce9146a8e73af7d14e
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

TGFBI MRC1 SPTLC2 RAB20 ZEB2

6.30e-05194965ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellMNPs|World / lung cells shred on cell class, cell subclass, sample id

TGFBI MRC1 LYZ MMP19 ZEB2

6.45e-05195965bd84ceae79115afd13346d8d66da30232a0952a9
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

MRC1 EFNA5 SCN3A CATSPERB NR6A1

6.45e-05195965de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellIPF-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

TGFBI MRC1 RAB20 MMP19 ZEB2

6.45e-0519596550edda117b438b9c3616191884007466f6d974f0
DrugNSC364150

TGFB1 GABRB2 TGFBI GABRG1 SOAT2 GABRA1

3.23e-0848896CID000100771
Drugmethohexital

GABRB2 GABRG1 LYZ GABRA1

2.18e-0624894CID000009034
DrugAC1L1BIT

GABRB2 GABRG1 PTCHD3 IDE GABRA1

3.76e-0660895CID000001457
Drugethanol

TGFB1 GABRB2 SELP GABRG1 SCN11A PTPA CS NTRK2 SCN3A SCN10A APOB EIF2AK3 GABRA1 SMG6

4.36e-068378914CID000000702
Drugtiotidine

GABRB2 GABRG1 GABRA1

4.77e-069893ctd:C023990
DrugSKF89976A

GABRB2 GABRG1 NTRK2 GABRA1

6.33e-0631894CID000092409
Drugforskolin from Coleus forskohlii

TGFB1 GABRB2 TGFBI GABRG1 PTPA EFNA5 SCN3A SCN10A CALCRL LYZ CREBBP EIF2AK3 EP300 GABRA1 DUOXA2

8.33e-0610138915CID000003413
Drugfosazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000037114
DrugC19H18ClN3O

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000027452
Drugflutoprazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000003400
DrugArfendazam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000065803
Drugcamazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000037367
DrugBu-1014

GABRB2 GABRG1 GABRA1

9.31e-0611893CID015942721
DrugZapizolam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000068832
DrugReclazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID003052777
Drugiclazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000068777
Drugmenitrazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000189875
Drugetiroxate

CS APOB SOAT2

9.31e-0611893CID000065683
DrugSerin hydrazid

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000041637
Drugsulazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000017931
Drugelfazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000065445
Drugtriflubazam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000031157
Druguldazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000034274
Druggidazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000121919
Drugfletazepam

GABRB2 GABRG1 GABRA1

9.31e-0611893CID000036834
DrugSB-205384

GABRB2 GABRG1 GABRA1

1.24e-0512893CID000197690
DrugU-93631

GABRB2 GABRG1 GABRA1

1.24e-0512893CID000197626
Drughaloxazolam

GABRB2 GABRG1 GABRA1

1.24e-0512893CID000003563
Drugdoxefazepam

GABRB2 GABRG1 GABRA1

1.24e-0512893CID000038668
Drugpivoxazepam

GABRB2 GABRG1 GABRA1

1.24e-0512893CID000068722
Drugrazobazam

GABRB2 GABRG1 GABRA1

1.24e-0512893CID000071228
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

AMBP SCN11A NTRK2 C7 PTPN21 LYZ SOAT2

1.28e-051988972216_UP
Drugisoflurane

TGFB1 GABRB2 TGFBI GABRG1 SCN3A SCN10A CREBBP GABRA1

1.38e-05279898CID000003763
DrugpH Q

GABRB2 GABRG1 PTCHD3 APOB GABRA1

1.46e-0579895CID000007708
Drugnerisopam

GABRB2 GABRG1 GABRA1

1.61e-0513893CID000065875
Drugflutazolam

GABRB2 GABRG1 GABRA1

1.61e-0513893CID000003398
Drug4-PIOL

GABRB2 GABRG1 GABRA1

1.61e-0513893CID000125520
DrugAC1MVFYM

GABRB2 GABRG1 GABRA1

1.61e-0513893CID003707225
DrugRo 11-3128

GABRB2 GABRG1 GABRA1

1.61e-0513893CID000093364
Drugcinolazepam

GABRB2 GABRG1 GABRA1

1.61e-0513893CID003033621
Drugalpha IMGBL

GABRB2 GABRG1 GABRA1

1.61e-0513893CID000131516
Drugmetaclazepam

GABRB2 GABRG1 GABRA1

1.61e-0513893CID000071272
Drugsodium

GABRB2 AMBP SELP GABRG1 TRPM4 ATP6V1H SLC12A3 SACS SCN3A PKD1 SCN10A PRPF8 LYZ GABRA1

1.70e-059448914CID000000923
Drugbeta-CCt

GABRB2 GABRG1 GABRA1

2.04e-0514893CID000124514
DrugMe-lex

GABRB2 GABRG1 GABRA1

2.04e-0514893CID000004177
Drugethyl loflazepate

GABRB2 GABRG1 GABRA1

2.04e-0514893CID000003299
DrugPK11195

GABRB2 GABRG1 IDE GABRA1

2.18e-0542894CID000001345
Drugcreatinine

TGFB1 AMBP TGFBI ABCA4 SLC12A3 PTCHD3 APOB NR6A1

2.43e-05302898CID000000588
DrugSR 95103

GABRB2 GABRG1 GABRA1

2.54e-0515893CID000125958
Drugpinazepam

GABRB2 GABRG1 GABRA1

2.54e-0515893CID000040391
Drugfludiazepam

GABRB2 GABRG1 GABRA1

2.54e-0515893CID000003369
DrugTBOB

GABRB2 GABRG1 GABRA1

2.54e-0515893CID000114986
Drugloprazolam

GABRB2 GABRG1 GABRA1

2.54e-0515893CID003033860
Drugpremazepam

GABRB2 GABRG1 GABRA1

2.54e-0515893CID000072104
Druggirisopam

GABRB2 GABRG1 GABRA1

2.54e-0515893CID000071257
DrugRo 5-4864

GABRB2 GABRG1 IDE GABRA1

2.63e-0544894CID000001688
Drugpregnanolone

GABRB2 GABRG1 SCN11A SERPINI1 GABRA1

2.76e-0590895CID000031402
Drugprocaine

GABRB2 GABRG1 SCN3A PKD1 SCN10A GABRA1

3.06e-05153896CID000004914
Drugtetrazepam

GABRB2 GABRG1 GABRA1

3.12e-0516893CID000025215
DrugP858

GABRB2 GABRG1 GABRA1

3.12e-0516893CID000004617
Drugnimetazepam

GABRB2 GABRG1 GABRA1

3.12e-0516893CID000004496
DrugRo 19-4603

GABRB2 GABRG1 GABRA1

3.12e-0516893CID000127382
Drugheptachlor epoxide

ESCO2 GABRB2 GABRG1 GABRA1

3.14e-0546894CID000013930
Drugflurothyl

GABRB2 GABRG1 SCN11A GABRA1

3.42e-0547894CID000009528
Drugimidazole-4-acetic acid

ESCO2 GABRB2 GABRG1 GABRA1

3.72e-0548894CID000096215
Drugdihydroxyaflavinine

GABRB2 GABRG1 GABRA1

3.77e-0517893CID000156857
DrugCL 218,872

GABRB2 GABRG1 GABRA1

3.77e-0517893CID000107950
Druglidocaine

GABRB2 GABRG1 SCN3A SCN10A ROS1 GABRA1

3.94e-05160896CID000003676
Drugabecarnil

GABRB2 GABRG1 GABRA1

4.52e-0518893CID000065914
Drugcloxazolam

GABRB2 GABRG1 GABRA1

4.52e-0518893CID000002816
Drugclorazepate

GABRB2 GABRG1 GABRA1

4.52e-0518893CID000002809
Druglormetazepam

GABRB2 GABRG1 GABRA1

4.52e-0518893CID000013314
Drugphenazepam

GABRB2 GABRG1 GABRA1

4.52e-0518893CID000040113
Drug1-(4-chlorophenyl)piperazine

GABRB2 GABRA1

4.52e-053892ctd:C026386
DrugNSC326198

TGFB1 ABCA4

4.52e-053892CID005359777
Drug1-(2-methoxyphenyl)piperazine

GABRB2 GABRA1

4.52e-053892ctd:C040083
DrugPREPARATIONS

CS APOB

4.52e-053892CID000019670
DrugBemegride

GABRB2 GABRA1

4.52e-053892ctd:D001534
Drugmenthone

GABRB2 GABRA1

4.52e-053892ctd:C019466
Drugcyclopentaphenanthrene

GABRB2 GABRA1

4.52e-053892ctd:C013460
Druggabazine

GABRB2 GABRA1

4.52e-053892ctd:C049853
Druggabapentin

GABRB2 GABRG1 SCN3A PKD1 SCN10A GABRA1

5.34e-05169896CID000003446
Drugetifoxine

GABRB2 GABRG1 GABRA1

5.35e-0519893CID000030768
DrugZK 93426

GABRB2 GABRG1 GABRA1

5.35e-0519893CID000115210
Drugtitanium

TGFB1 ESCO2 AMBP SELP ROS1 MMP19

5.52e-05170896CID000023963
Drughalazepam

GABRB2 GABRG1 GABRA1

6.27e-0520893CID000031640
DrugAC1N65YL

GABRB2 GABRG1 GABRA1

6.27e-0520893CID004229818
DrugRo 15-4513

GABRB2 GABRG1 GABRA1

6.27e-0520893CID000005081
DrugEBOB

GABRB2 GABRG1 GABRA1

6.27e-0520893CID000115223
Drugriluzole

GABRB2 GABRG1 SCN3A PKD1 SCN10A GABRA1

6.28e-05174896CID000005070
Drugprazepam

GABRB2 GABRG1 GABRA1

7.30e-0521893CID000004890
Drugbicuculline methochloride

GABRB2 GABRG1 GABRA1

7.30e-0521893CID000123659
DrugR 5135

GABRB2 GABRG1 GABRA1

7.30e-0521893CID000119544
DrugEllipticine [519-23-3]; Down 200; 16.2uM; HL60; HG-U133A

PCYOX1L UTP25 SACS SPTLC2 BCL11A EMC2

7.58e-051808961765_DN
DrugNSC7524

TGFB1 TGFBI SCN3A PKD1 SCN10A EIF2AK3

8.06e-05182896CID000005657
DrugIomazenil (123I

GABRB2 GABRG1 GABRA1

8.43e-0522893CID000065959
Drugquazepam

GABRB2 GABRG1 GABRA1

8.43e-0522893CID000004999
Drugetizolam

GABRB2 GABRG1 GABRA1

8.43e-0522893CID000003307
Drug6 mEq

GABRB2 GABRG1 GABRA1

8.43e-0522893CID000126186
Drugimidazenil

GABRB2 GABRG1 GABRA1

8.43e-0522893CID000119194
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN3A SCN10A

3.13e-0610893DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN3A SCN10A

3.13e-0610893DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN3A SCN10A

5.72e-0612893DOID:0060170 (implicated_via_orthology)
DiseaseColorectal Carcinoma

TGFB1 HHIP ABCA4 SACS LAMA1 TENM1 APOB CSMD3 SNRNP200 ZEB2 EP300

8.67e-067028911C0009402
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

9.00e-062892180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

9.00e-062892cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

9.00e-062892cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

9.00e-062892DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

9.00e-062892cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

9.00e-062892C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

9.00e-062892DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

9.00e-062892C0035934
DiseaseMood Disorders

TGFB1 GABRB2 AMBP HCN4 NTRK2 GABRA1

1.22e-05168896C0525045
DiseasePrimary Erythermalgia

SCN11A SCN10A

2.69e-053892C0014805
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN10A

2.69e-053892C1833661
DiseaseObesity

MRC1 CS NTRK2 BBS12 EP300 TMEM18

3.76e-05205896C0028754
DiseaseBrugada Syndrome (disorder)

TRPM4 HCN4 SCN10A

5.13e-0524893C1142166
DiseaseCongenital Pain Insensitivity

SCN11A SCN10A

1.87e-047892C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN10A

1.87e-047892C0020075
Diseaseretinitis pigmentosa (is_implicated_in)

ABCA4 PRPF8 SNRNP200

2.60e-0441893DOID:10584 (is_implicated_in)
DiseaseCarcinoma, Transitional Cell

AMBP CREBBP EP300

2.60e-0441893C0007138
DiseaseRetinitis Pigmentosa

ABCA4 DHX38 PRPF8 SNRNP200

2.82e-04104894C0035334
DiseaseOther specified cardiac arrhythmias

HCN4 SCN10A

4.86e-0411892C0348626
DiseaseNodal rhythm disorder

HCN4 SCN10A

4.86e-0411892C0264893
DiseaseEctopic rhythm

HCN4 SCN10A

4.86e-0411892C1399226
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

HCN4 SCN10A

4.86e-0411892C2748542
DiseaseOrofacial cleft

ABCA4 UTP25 NR6A1

4.97e-0451893HP_0000202
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

AMBP EFNA5 SPTLC2 CSMD3 TENM2

5.06e-04216895EFO_0007925, EFO_0007927
Diseasecerebellar volume measurement

HHIP PTPA EIF2AK3

5.27e-0452893EFO_0020864
Diseaseangina pectoris

TGFB1 DHX38 APOB SMG6

5.67e-04125894EFO_0003913
DiseaseBrugada Syndrome 1

HCN4 SCN10A

6.87e-0413892C4551804
Diseasemyelodysplastic syndrome (implicated_via_orthology)

PRPF8 CREBBP

9.21e-0415892DOID:0050908 (implicated_via_orthology)
DiseaseSinus Node Dysfunction (disorder)

HCN4 SCN10A

9.21e-0415892C0428908
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

TGFB1 APOB SMG6

9.24e-0463893EFO_0001645, EFO_0004792
Diseasesickle cell anemia (is_implicated_in)

APOB BCL11A

1.05e-0316892DOID:10923 (is_implicated_in)
Diseasediabetic neuropathy (biomarker_via_orthology)

TGFB1 HHIP

1.19e-0317892DOID:9743 (biomarker_via_orthology)
DiseaseFamilial Progressive Myoclonic Epilepsy

SERPINI1 SACS

1.19e-0317892C0751777
DiseaseAtypical Inclusion-Body Disease

SERPINI1 SACS

1.19e-0317892C0751776
DiseaseMyoclonic Epilepsies, Progressive

SERPINI1 SACS

1.19e-0317892C0751778
DiseaseBiotin-Responsive Encephalopathy

SERPINI1 SACS

1.19e-0317892C0751780
DiseaseMay-White Syndrome

SERPINI1 SACS

1.19e-0317892C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

SERPINI1 SACS

1.19e-0317892C0751781
Diseasetissue plasminogen activator measurement, coronary artery disease

TGFB1 APOB SMG6

1.31e-0371893EFO_0001645, EFO_0004791
DiseaseAlcoholic Intoxication, Chronic

GABRB2 GABRG1 NTRK2 EP300 GABRA1

1.33e-03268895C0001973
DiseaseAction Myoclonus-Renal Failure Syndrome

SERPINI1 SACS

1.33e-0318892C0751779
DiseaseSchizophrenia

TGFB1 GABRB2 SERPINI1 NTRK2 LAMA1 BCL11A IDE PTPN21 GABRA1

1.39e-03883899C0036341
Diseasemyocardial infarction (biomarker_via_orthology)

TGFB1 SELP C7 ZEB2

1.42e-03160894DOID:5844 (biomarker_via_orthology)
DiseaseRetinitis pigmentosa

ABCA4 PRPF8 SNRNP200

1.47e-0374893cv:C0035334
Diseaseepilepsy (implicated_via_orthology)

SCN11A SLC12A3 SCN3A SCN10A

1.52e-03163894DOID:1826 (implicated_via_orthology)
DiseaseColorectal Neoplasms

TGFB1 HHIP ABCA4 LAMA1 EP300

1.54e-03277895C0009404
Diseaseinterleukin 18 measurement

SCN11A SCN10A WDR59

1.59e-0376893EFO_0004581
Diseasecoagulation factor V measurement

SELP SUSD1

1.65e-0320892EFO_0008087
Diseaseneuroimaging measurement, brain volume measurement

MRC1 CATSPERB CALCRL EMC2 SCAI

1.77e-03286895EFO_0004346, EFO_0006930
Diseasecortical thickness

HHIP VPS13D FBXW10 ABCA4 EFNA5 LAMA1 PKD1 CALCRL TENM2 SMG6

1.92e-0311138910EFO_0004840
DiseaseRenal glomerular disease

SLC12A3 CREBBP

2.18e-0323892C0268731
DiseaseGlomerulopathy Assessment

SLC12A3 CREBBP

2.18e-0323892C4521256
Diseaseidiopathic pulmonary fibrosis (is_marker_for)

NTRK2 EP300

2.18e-0323892DOID:0050156 (is_marker_for)
Diseaseliver fibrosis measurement

TGFB1 MRC1 APOB

2.27e-0386893EFO_0010576
DiseaseSepticemia

TGFB1 TGFBI

2.38e-0324892C0036690
DiseaseSepsis

TGFB1 TGFBI

2.38e-0324892C0243026
DiseaseSevere Sepsis

TGFB1 TGFBI

2.38e-0324892C1719672
DiseasePyemia

TGFB1 TGFBI

2.38e-0324892C0034189
Diseasenephrotic syndrome (biomarker_via_orthology)

APOB SOAT2

2.38e-0324892DOID:1184 (biomarker_via_orthology)
Diseaseheart failure

PKD1 ZEB2 TMEM18 SMG6

2.41e-03185894EFO_0003144
Diseaseatopic dermatitis (is_implicated_in)

TGFB1 SELP

2.79e-0326892DOID:3310 (is_implicated_in)
Diseasemigraine disorder, pulse pressure measurement

TGFB1 SMG6

2.79e-0326892EFO_0005763, MONDO_0005277
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

GABRB2 MRPS30 EFNA5 BCL11A TENM2 SCAI TMEM18 SMG6

2.91e-03801898EFO_0003888, EFO_0007052, MONDO_0002491
Diseaseretinitis pigmentosa (implicated_via_orthology)

PRPF8 SNRNP200

3.01e-0327892DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GTNRKYFTNCKQWYQ

TGFBI

56

Q15582
VQENFNISRIYGKWY

AMBP

31

P02760
KQDQDYYFFLASNWR

CATSPERG

716

Q6ZRH7
TSWGDSRQAQASYYK

SMG6

486

Q86US8
QASDTANYGKARSWY

SMG6

741

Q86US8
NNAWLYNRKTSRVYK

EP300

1126

Q09472
YNFGQRNGRTWKIYS

CATSPERB

701

Q9H7T0
AQNYIWKGSYNFKGR

CSMD3

3496

Q7Z407
SWNDIKNSGYISRYL

EIF2AK3

576

Q9NZJ5
GSRVLSFNWYEDNNY

ABCA4

331

P78363
QYSRYGFGKSFNSLW

AMBN

61

Q9NP70
NITWALKRYGFYNNS

ARSI

276

Q5FYB1
LRTKNEYNLWTAYQN

FBXW10

371

Q5XX13
FNNAWLYNRKTSRVY

CREBBP

1161

Q92793
LANGWQKYLSTLLYN

BBS12

591

Q6ZW61
TVGGAFYLKQWRSYN

RAB20

36

Q9NX57
QKRYQDWFQRQYLST

INTS3

326

Q68E01
KSTGLNFNLHWRFYY

HPF1

96

Q9NWY4
LRTKNEYNLWTAYQN

FBXW10B

371

O95170
RASQSISSYLNWYQQ

IGKV1D-39

46

P04432
GSLWSFNYFFYNKRL

MAF1

181

Q9H063
KWESGYNTRATNYNA

LYZ

51

P61626
RFNWLGNFYIVLSYN

LMBR1

421

Q8WVP7
YSQWLAGYAASRQLK

BCL11A

656

Q9H165
VAAKNVALLAYNRWY

PCYOX1L

461

Q8NBM8
YFFKGKVYWRLNQQL

MMP19

441

Q99542
FGIFNLVYWATYLNR

GABRA1

431

P14867
YFQQAWRDKRLSYNV

GABRB2

86

P47870
NLYIYFAWQGKTQIS

MFSD11

151

O43934
MVNNSWGKQYSYALF

HCN4

456

Q9Y3Q4
DLNWQTRKYNTKAAY

RDH13

186

Q8NBN7
VTYFSLWYYNKQNQR

PTPN21

61

Q16825
YWLNNYVFKNALRLG

PORCN

311

Q9H237
YNEQFTWRLKENYAA

DUOXA2

126

Q1HG44
YLQRKYNDALAWSFG

ADAM30

296

Q9UKF2
SWQVSARFNQYKYNQ

APOB

3086

P04114
KYWRLYQFAFVGLRN

GABRG1

231

Q8N1C3
ESWNLLSRTNYNFQY

GPAT4

141

Q86UL3
WQLSTKEGVRASYNY

DHX57

1131

Q6P158
FARAYAQGISRTKYW

CS

181

O75390
KINNDFNYEFYNSTW

C7

191

P10643
LSTVSFYNQNKWYLN

ESCO2

81

Q56NI9
YSSYYWIGIRKNNKT

SELP

86

P16109
KAVADRYAVYWNSSN

EFNA5

26

P52803
RASQGISSYLAWYQQ

IGKV1-9

46

A0A0C4DH69
RASQGISNYLAWYQQ

IGKV1-27

46

A0A075B6S5
RASQSISSYLNWYQQ

IGKV1-39

46

P01597
YSSNNKNYLAWYQQK

IGKV4-1

51

P06312
KYWGEIISQQYNFDR

IDE

906

P14735
VVYQYWNTKARRNEF

EMC1

791

Q8N766
YASWAASQINRAYQF

EMC2

256

Q15006
KYSFQRFYTSWNQEA

SACS

4391

Q9NZJ4
RRNWNQYKIQFGNSF

CALCRL

396

Q16602
TRWYFKYFLGQVHQN

GARNL3

96

Q5VVW2
FWLDAYVQYLKGNSQ

PTCHD3

696

Q3KNS1
RVAYAWYFSLQKVQG

PKD1

2001

P98161
TYLALINAVYFKGNW

SERPINI1

176

Q99574
FLWKYVNRNDAQSAY

MRC1

846

P22897
TSASQLEQLNKRYWY

NR6A1

406

Q15406
FPYYRANQRAWQNSI

FOXL3

66

A0A1W2PRP0
QTFALNADRWYQYFT

MRPS30

96

Q9NP92
LNNWSKYYRQTLLFG

UTP25

521

Q68CQ4
LNYYFNWIKTQLSSQ

ATP6V1H

161

Q9UI12
RYNNGTWYKIAFQRN

LAMA1

2381

P25391
WNQASINYYTSRGAL

SATL1

656

Q86VE3
DKTQWRYSYDLNGNI

TENM1

2166

Q9UKZ4
LTRAYNKASGWSVQY

TENM2

2286

Q9NT68
LLKWVAYGFQTYFTN

SCN3A

1256

Q9NY46
NGKLYVSYTTNQERW

HHIP

296

Q96QV1
LSKYTNLLQGWQNRY

OSBPL10

81

Q9BXB5
YVRWNYVAKNFAQAL

SOAT2

291

O75908
QWFYNGAILNESKYI

NTRK2

316

Q16620
SRKYVNGSTYQRWQF

PRPF8

216

Q6P2Q9
AYNRFFKESWPQYSQ

UBTFL1

106

P0CB47
RQSHDYNWSFKYTGN

SPTLC2

151

O15270
QPSRFGNKAYRTWYA

PTPA

131

Q15257
KMFALRQYYFTNGWN

SCN10A

1526

Q9Y5Y9
YAYDGNRVRKWNVTT

RNF123

171

Q5XPI4
YQFTVLGQRWYLANF

SUSD1

426

Q6UWL2
YQKYSNNSWRYLSNR

TGFB1

171

P01137
YSVSRFNNLQWYRQN

TRAV7

46

A0A075B6U4
SFQYYNKWAALFGAI

SLC12A3

561

P55017
QYGQKQWQSYFGRTF

SCAI

81

Q8N9R8
QWQSYFGRTFDVYTK

SCAI

86

Q8N9R8
YLNVYLQWKNNNYST

DHX38

1011

Q92620
SANFSGVKYIIQWKY

ROS1

121

P08922
YGYIFSLKNWNSSNI

SUCNR1

46

Q9BXA5
GQGVSSWKRAFYYNA

TINCR

46

A0A2R8Y7D0
IYYQKWINATISRAN

PRSS48

256

Q7RTY5
YFAASSNQRVDLYKW

WDR59

76

Q6PJI9
QNAKDAVNWLGYAYL

SNRNP200

911

O75643
VSKNGFFQGYNRLTW

SLC35A3

231

Q9Y2D2
KIFALRQYYFTNGWN

SCN11A

1416

Q9UI33
WFEQRKVYQYSNSRS

ZEB2

691

O60315
NWRLFSKYQYFDSRG

TMEM18

76

Q96B42
QGNSDLYWKAQRYRL

TRPM4

1051

Q8TD43
STWNYQKSTIGAYFL

WDR36

471

Q8NI36
VAWVLNTYLGKYVNN

VPS13D

6

Q5THJ4
WNTFYQYLQSPFSKF

LEG1

186

Q6P5S2