Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN2B SCN8A SCN9A	1.56e-04	26	81	3	GO:0005248
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	KCND3 SCN2B SCN8A SCN9A RYR2	4.21e-06	62	80	5	GO:0086002
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	KCND3 SCN2B SCN8A SCN9A RYR2	2.23e-05	87	80	5	GO:0086001
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	KCND3 SCN2B SCN8A SCN9A RYR2	3.08e-05	93	80	5	GO:0086003
GeneOntologyBiologicalProcess	response to magnesium ion	SLFN14 D2HGDH RYR2	1.22e-04	25	80	3	GO:0032026
GeneOntologyBiologicalProcess	action potential	KCND3 SCN2B SCN8A SCN9A CNR1 RYR2	1.31e-04	201	80	6	GO:0001508
GeneOntologyBiologicalProcess	actin-mediated cell contraction	KCND3 SCN2B SCN8A SCN9A RYR2	1.36e-04	127	80	5	GO:0070252
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN2B SCN8A SCN9A	3.66e-05	17	81	3	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN2B SCN8A SCN9A	1.90e-04	29	81	3	GO:0034706
GeneOntologyCellularComponent	transporter complex	ATP8B4 ATP6V1H KCND3 SCN2B SCN8A SCN9A RYR2 AMIGO1 ATP6V0A2	2.74e-04	550	81	9	GO:1990351
GeneOntologyCellularComponent	cation channel complex	KCND3 SCN2B SCN8A SCN9A RYR2 AMIGO1	3.04e-04	235	81	6	GO:0034703
Domain	ARM-type_fold	FMNL3 RIF1 ATP6V1H PPP2R5C INSC CTNNBL1 LRBA UNC79 FMNL1 PPP4R3A	1.61e-06	339	79	10	IPR016024
Domain	CLCA_chordata	CLCA4 CLCA2	5.29e-05	3	79	2	IPR004727
Domain	CLCA	CLCA4 CLCA2	5.29e-05	3	79	2	PF08434
Domain	CLCA	CLCA4 CLCA2	5.29e-05	3	79	2	IPR013642
Domain	DUF3523	ATAD3B ATAD3C	5.29e-05	3	79	2	PF12037
Domain	DUF3523	ATAD3B ATAD3C	5.29e-05	3	79	2	IPR021911
Domain	ARM-like	RIF1 ATP6V1H PPP2R5C INSC CTNNBL1 LRBA PPP4R3A	1.46e-04	270	79	7	IPR011989
Domain	Na_trans_cytopl	SCN8A SCN9A	2.62e-04	6	79	2	PF11933
Domain	Na_trans_cytopl	SCN8A SCN9A	2.62e-04	6	79	2	IPR024583
Domain	-	RIF1 ATP6V1H PPP2R5C INSC CTNNBL1 LRBA	3.56e-04	222	79	6	1.25.10.10
Domain	Drf_GBD	FMNL3 FMNL1	6.24e-04	9	79	2	PF06371
Domain	FH3_dom	FMNL3 FMNL1	6.24e-04	9	79	2	IPR010472
Domain	GTPase-bd	FMNL3 FMNL1	6.24e-04	9	79	2	IPR010473
Domain	Drf_FH3	FMNL3 FMNL1	6.24e-04	9	79	2	PF06367
Domain	Drf_FH3	FMNL3 FMNL1	6.24e-04	9	79	2	SM01139
Domain	Drf_GBD	FMNL3 FMNL1	6.24e-04	9	79	2	SM01140
Domain	Na_channel_asu	SCN8A SCN9A	7.78e-04	10	79	2	IPR001696
Domain	Na_trans_assoc	SCN8A SCN9A	7.78e-04	10	79	2	IPR010526
Domain	Na_trans_assoc	SCN8A SCN9A	7.78e-04	10	79	2	PF06512
Domain	GBD/FH3_dom	FMNL3 FMNL1	9.48e-04	11	79	2	IPR014768
Domain	GBD_FH3	FMNL3 FMNL1	9.48e-04	11	79	2	PS51232
Domain	EF-hand-dom_pair	TBC1D8 S100B EFCAB13 SCN8A SCN9A RYR2	1.36e-03	287	79	6	IPR011992
Domain	AAA	ORC4 ATAD3B ATAD3C	1.39e-03	52	79	3	PF00004
Domain	Ion_trans_dom	KCND3 SCN8A SCN9A RYR2	1.39e-03	114	79	4	IPR005821
Domain	Ion_trans	KCND3 SCN8A SCN9A RYR2	1.39e-03	114	79	4	PF00520
Domain	ATPase_AAA_core	ORC4 ATAD3B ATAD3C	1.55e-03	54	79	3	IPR003959
Domain	FH2	FMNL3 FMNL1	1.79e-03	15	79	2	PS51444
Domain	FH2_Formin	FMNL3 FMNL1	1.79e-03	15	79	2	IPR015425
Domain	FH2	FMNL3 FMNL1	1.79e-03	15	79	2	PF02181
Domain	FH2	FMNL3 FMNL1	1.79e-03	15	79	2	SM00498
Domain	Channel_four-helix_dom	KCND3 SCN8A SCN9A	1.81e-03	57	79	3	IPR027359
Domain	-	KCND3 SCN8A SCN9A	1.81e-03	57	79	3	1.20.120.350
Domain	GRAM	TBC1D8 SBF1	2.04e-03	16	79	2	SM00568
Domain	GRAM	TBC1D8 SBF1	3.86e-03	22	79	2	PF02893
Domain	GRAM	TBC1D8 SBF1	3.86e-03	22	79	2	IPR004182
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	CLCA4 ATP8B4 ATP6V1H CLCA2 UNC79 RYR2 ATP6V0A2	1.16e-05	176	62	7	MM15718
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	CLCA4 ATP8B4 ATP6V1H CLCA2 UNC79 RYR2 ATP6V0A2	1.49e-05	183	62	7	M997
Pathway	REACTOME_CARDIAC_CONDUCTION	KCND3 HIPK1 SCN2B SCN8A SCN9A RYR2	2.21e-05	130	62	6	M27454
Pathway	REACTOME_MUSCLE_CONTRACTION	KCND3 HIPK1 SCN2B SCN8A SCN9A RYR2	2.60e-04	203	62	6	M5485
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN2B SCN8A SCN9A	3.34e-04	31	62	3	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN2B SCN8A SCN9A	3.67e-04	32	62	3	M27455
Pubmed	Expression analysis of ATAD3 isoforms in rodent and human cell lines and tissues.	S100B ATAD3B ATAD3C	1.26e-07	5	82	3	24239551
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DMXL2 ATAD3B ZBTB2 ATP8B4 ATAD3C DNAH17 WDR35 AMIGO1 PPP4R3A	2.52e-06	493	82	9	15368895
Pubmed	Molecular and functional analyses of two new calcium-activated chloride channel family members from mouse eye and intestine.	CLCA4 CLCA2	5.49e-06	2	82	2	15284223
Pubmed	Sodium channel slow inactivation interferes with open channel block.	SCN8A SCN9A	5.49e-06	2	82	2	27174182
Pubmed	Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids.	BECN2 CNR1	1.64e-05	3	82	2	27305347
Pubmed	Structure of human NaV1.6 channel reveals Na+ selectivity and pore blockade by 4,9-anhydro-tetrodotoxin.	SCN2B SCN8A	1.64e-05	3	82	2	36823201
Pubmed	Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.	FMNL3 FMNL1	1.64e-05	3	82	2	12684686
Pubmed	[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].	ATAD3B ATAD3C	1.64e-05	3	82	2	22192748
Pubmed	Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system.	CLCA4 CLCA2	1.64e-05	3	82	2	19210762
Pubmed	ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.	ATAD3B ATAD3C	1.64e-05	3	82	2	28549128
Pubmed	Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.	CLCA4 CLCA2	1.64e-05	3	82	2	16569774
Pubmed	Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins.	SCN2B SCN9A	1.64e-05	3	82	2	30765606
Pubmed	ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte-like 3T3-L1 cells.	ATAD3B ATAD3C	1.64e-05	3	82	2	38923254
Pubmed	Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.	CLCA4 CLCA2	1.64e-05	3	82	2	10437792
Pubmed	ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly.	ATAD3B ATAD3C	1.64e-05	3	82	2	34936866
Pubmed	Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3.	ATAD3B ATAD3C	1.64e-05	3	82	2	25375035
Pubmed	Bi-modal regulation of a formin by srGAP2.	FMNL3 FMNL1	1.64e-05	3	82	2	21148482
Pubmed	Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.	SCN8A SCN9A	1.64e-05	3	82	2	15302875
Pubmed	ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.	ATAD3B ATAD3C	3.28e-05	4	82	2	35236834
Pubmed	Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis.	ATAD3B ATAD3C	3.28e-05	4	82	2	36736924
Pubmed	The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy.	ATAD3B ATAD3C	3.28e-05	4	82	2	38250153
Pubmed	Evolution and diversity of mammalian sodium channel genes.	SCN2B SCN9A	3.28e-05	4	82	2	10198179
Pubmed	Atad3a suppresses Pink1-dependent mitophagy to maintain homeostasis of hematopoietic progenitor cells.	ATAD3B ATAD3C	3.28e-05	4	82	2	29242539
Pubmed	Molecular characteristics and functional diversity of CLCA family members.	CLCA4 CLCA2	3.28e-05	4	82	2	11071307
Pubmed	Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current.	SCN2B SCN8A	3.28e-05	4	82	2	15664175
Pubmed	Differential effects of extracellular ATP on chloride transport in cortical collecting duct cells.	CLCA4 CLCA2	5.47e-05	5	82	2	22647633
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN8A SCN9A	5.47e-05	5	82	2	22875929
Pubmed	ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels.	ATAD3B ATAD3C	5.47e-05	5	82	2	29898916
Pubmed	Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.	SCN8A SCN9A	8.19e-05	6	82	2	16029194
Pubmed	Isolation of genes differentially expressed in human primary myoblasts and embryonal rhabdomyosarcoma.	JAG1 SCN8A	8.19e-05	6	82	2	8635876
Pubmed	Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation.	ATAD3B ATAD3C	8.19e-05	6	82	2	31472450
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN8A SCN9A	8.19e-05	6	82	2	23652591
Pubmed	Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes.	TUBB1 PRMT1	1.52e-04	8	82	2	14583623
Pubmed	ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.	ATAD3B ATAD3C	1.52e-04	8	82	2	30914652
Pubmed	Atad3 function is essential for early post-implantation development in the mouse.	ATAD3B ATAD3C	1.52e-04	8	82	2	23372768
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	S100B DMXL2 ATAD3B ATAD3C DNAH17 HPF1 PACSIN3 PRMT1 SCAF11 AGAP9 FBXO47	1.58e-04	1242	82	11	30973865
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN8A SCN9A	1.96e-04	9	82	2	16382098
Pubmed	BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade.	MATK REV1	1.96e-04	9	82	2	23901102
Pubmed	Transcriptional regulation of intermediate progenitor cell generation during hippocampal development.	S100B INSC	1.96e-04	9	82	2	27965439
Pubmed	A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.	KCND3 SLFN14	2.44e-04	10	82	2	24785509
Pubmed	Accelerating functional gene discovery in osteoarthritis.	DNAH17 HPF1 SCAF11	2.72e-04	53	82	3	33473114
Pubmed	Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast.	ATAD3B ATAD3C	2.98e-04	11	82	2	36000457
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCND3 SCN8A SCN9A RYR2	3.36e-04	139	82	4	16985003
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN2B SCN8A	3.57e-04	12	82	2	30175250
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	DMXL2 ATAD3B ATAD3C SBF1	4.15e-04	147	82	4	16959763
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN8A SCN9A	4.21e-04	13	82	2	15123669
Pubmed	Structure and Roles of V-type ATPases.	ATP6V1H ATP6V0A2	4.21e-04	13	82	2	32001091
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	S100B ZBTB2 ZBTB1	4.53e-04	63	82	3	34351428
Pubmed	HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation.	CLCA4 CLCA2	4.91e-04	14	82	2	10758170
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMNL3 FMNL1	4.91e-04	14	82	2	26272686
Pubmed	Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.	ATP6V1H ATP6V0A2	7.30e-04	17	82	2	33065002
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ORC4 RIF1 PPP2R5C SBF1 INTS11 CTNNBL1 PACSIN3 PRMT1 POLR1B SCAF11 ATP6V0A2	7.67e-04	1497	82	11	31527615
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	ATAD3B RGS18 KCND3 SCN2B SCN8A WDR35 TMEM150C NFAT5	7.77e-04	832	82	8	36724073
Pubmed	Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism.	BECN2 CNR1	8.20e-04	18	82	2	23954414
Pubmed	Genome-wide association of mood-incongruent psychotic bipolar disorder.	ATP6V1H LRBA	8.20e-04	18	82	2	23092984
Pubmed	Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.	S100B JAG1	9.15e-04	19	82	2	16518823
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	SCN8A SCN9A PACSIN3 NFAT5 FMNL1 PREX2	9.17e-04	475	82	6	31040226
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	FMNL3 ATAD3B ATAD3C NFAT5 UNC79	9.91e-04	321	82	5	32098917
Pubmed	Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.	ATP6V1H ATP6V0A2	1.01e-03	20	82	2	22982048
Pubmed	Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.	S100B JAG1	1.12e-03	21	82	2	28656980
Pubmed	The vacuolar (H+)-ATPases--nature's most versatile proton pumps.	ATP6V1H ATP6V0A2	1.23e-03	22	82	2	11836511
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	SPHKAP CNR1	1.23e-03	22	82	2	26494785
Pubmed	Proton translocation driven by ATP hydrolysis in V-ATPases.	ATP6V1H ATP6V0A2	1.23e-03	22	82	2	12788495
Pubmed	Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.	ATP6V1H ATP6V0A2	1.23e-03	22	82	2	14580332
Pubmed	Neurotransmitter release: the dark side of the vacuolar-H+ATPase.	ATP6V1H ATP6V0A2	1.23e-03	22	82	2	14597263
Pubmed	Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.	FMNL3 ATAD3B ATAD3C	1.24e-03	89	82	3	27034005
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DMXL2 ATAD3B PPP2R5C ATAD3C KCND3 SPHKAP PRMT1 ACTL6B RYR2	1.45e-03	1139	82	9	36417873
Pubmed	Brugada Syndrome	KCND3 SCN2B	1.47e-03	24	82	2	20301690
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FMNL3 PPP2R5C SBF1 UBXN7 SCAF11 AGAP9	1.59e-03	529	82	6	14621295
Pubmed	Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.	ATP6V1H ATP6V0A2	1.59e-03	25	82	2	2874839
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	DMXL2 PPP2R5C KCND3 HIPK1 DNAH17 PRMT1 ATP6V0A2	1.70e-03	730	82	7	34857952
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	RIF1 KANK3 POLR1B SCAF11 AGAP9 REV1	1.73e-03	538	82	6	10512203
Pubmed	The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia.	ATAD3B UBXN7 PRMT1	1.83e-03	102	82	3	37024974
Pubmed	NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.	SCN9A ACTL6B	1.86e-03	27	82	2	23359859
Pubmed	Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.	DMXL2 ATP6V1H	1.86e-03	27	82	2	26442671
Pubmed	An integrated workflow for charting the human interaction proteome: insights into the PP2A system.	ATAD3B PPP2R5C PPP4R3A	1.99e-03	105	82	3	19156129
Pubmed	Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.	ZBTB2 NFAT5	1.99e-03	28	82	2	29365100
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ATP6V1H SBF1 UBXN7 PRMT1 UPP1 EXT2 PLOD1 PPP4R3A	2.11e-03	974	82	8	28675297
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	FMNL3 FMNL1	2.14e-03	29	82	2	21834987
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	PPP2R5C SPHKAP AMIGO1	2.27e-03	110	82	3	27889896
Cytoband	1p36.33	ATAD3B ATAD3C INTS11	3.65e-04	77	82	3	1p36.33
Cytoband	15q15.3	ZSCAN29 STRCP1	9.21e-04	25	82	2	15q15.3
Cytoband	15q21.2	DMXL2 ATP8B4	1.24e-03	29	82	2	15q21.2
Cytoband	14q32.12	UNC79 PPP4R3A	1.24e-03	29	82	2	14q32.12
Cytoband	1q43	BECN2 RYR2	3.80e-03	51	82	2	1q43
Cytoband	Ensembl 112 genes in cytogenetic band chr2q23	ORC4 RIF1	4.09e-03	53	82	2	chr2q23
GeneFamily	Chloride channel accessory	CLCA4 CLCA2	5.84e-05	4	57	2	867
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN8A SCN9A	3.47e-04	9	57	2	1203
GeneFamily	AAA ATPases	ORC4 ATAD3B ATAD3C	6.22e-04	53	57	3	413
GeneFamily	V-type ATPases	ATP6V1H ATP6V0A2	2.37e-03	23	57	2	415
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000	CHIC2 RIF1 DMXL2 ATP6V1H KANK3 TKTL1 CNR1 RYR2	3.42e-07	179	79	8	gudmap_developingGonad_e14.5_ ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_500	DMXL2 KANK3 TKTL1 CNR1 RYR2	2.27e-05	91	79	5	gudmap_developingGonad_e14.5_ ovary_500_k5
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000	RIF1 DMXL2 ATP6V1H KANK3 TKTL1 CNR1 RYR2	2.39e-05	230	79	7	gudmap_developingGonad_e18.5_ovary_1000_k5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100B CLCA4 TMEM45B SPHKAP UNC79 RYR2	8.71e-07	175	82	6	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	Neuroendocrine-neuroendo-2-Calca\|World / Class top	TMEM45B SCN8A SCN9A UPP1 ACTL6B FMNL1	1.36e-06	189	82	6	6baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	TBC1D8 S100B RGS18 SCN9A TMEM150C IFI30	1.59e-06	194	82	6	e2d9186a7e8d1a4a71d7bd6dba7fc955d55479e6
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	TBC1D8 S100B DMXL2 TMEM45B FASTKD1 TMEM150C	1.73e-06	197	82	6	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	TBC1D8 S100B DMXL2 TMEM45B FASTKD1 TMEM150C	1.73e-06	197	82	6	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	COVID-19-Mast_cells-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	TUBB1 RGS18 POLR1B TKTL1 SLFN14	6.33e-06	141	82	5	0fc06c2325249aa4ae65c0ace1ec3f953372f2e4
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RGS18 DNAH17 IFI30 UPP1 ZBTB1	1.00e-05	155	82	5	77ae0b8d30bc3db4a73fd5340f99691a73d2684f
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 RGS18 HPF1 IFI30 FMNL1	1.07e-05	157	82	5	904cd98ae85ed6459e0663f077ac462842bf12df
ToppCell	droplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D8 RHPN1 RGS18 SCN2B FMNL1	1.48e-05	168	82	5	ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCell	droplet-Liver-Npc-18m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D8 RHPN1 RGS18 SCN2B FMNL1	1.48e-05	168	82	5	22c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS18 MATK SCN2B IFI30 FMNL1	1.66e-05	172	82	5	cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100B RGS18 CLCA2 INSC SCN9A	1.80e-05	175	82	5	c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100B RGS18 CLCA2 INSC SCN9A	1.80e-05	175	82	5	c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100B RGS18 CLCA2 INSC SCN9A	1.80e-05	175	82	5	2f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 RGS18 MATK TKTL1 FMNL1	1.85e-05	176	82	5	3d372c1d527fcc118d1e5809f2524fc387682472
ToppCell	facs-Skin-Telogen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 RGS18 MATK TKTL1 FMNL1	1.85e-05	176	82	5	7b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 RGS18 MATK TKTL1 FMNL1	1.85e-05	176	82	5	9c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCell	15-Distal-Epithelial-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	TUBB1 S100B RGS18 SBF1 INSC	2.06e-05	180	82	5	99e2db9ad8e09fedc3542233553acece69f579f1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP SCN2B UNC79 CNR1 RYR2	2.06e-05	180	82	5	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	AREL1 DMXL2 LRSAM1 WDR35 TKTL1	2.23e-05	183	82	5	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP SCN2B SCN8A ACTL6B CNR1	2.29e-05	184	82	5	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D1 KANK3 JAG1 UPP1 NFAT5	2.35e-05	185	82	5	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D1 KANK3 JAG1 UPP1 NFAT5	2.35e-05	185	82	5	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	proximal-3-Hematologic-Myeloid_Dendritic_Type_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMNL3 S100B RGS18 WDR35 UNC79	2.41e-05	186	82	5	c920dffd24f051b54d8b48f801fffc928d99e135
ToppCell	proximal-Hematologic-Myeloid_Dendritic_Type_1-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMNL3 S100B RGS18 WDR35 UNC79	2.41e-05	186	82	5	d740aca5dc4240851ba7bc5988c0970d785ad0c2
ToppCell	proximal-Hematologic-Myeloid_Dendritic_Type_1\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FMNL3 S100B RGS18 WDR35 UNC79	2.41e-05	186	82	5	4ca7f6c043874a0c536f75af5ca24c7c66725e54
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 PPP2R5C SCN2B PRMT1 ST6GALNAC4	2.41e-05	186	82	5	af038994a6c32261f426b0c40c39be4a9099fe43
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-CMP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ATP8B4 MATK LAPTM4B PRMT1 PREX2	2.41e-05	186	82	5	895905f1d1a01ffd5617a0baa8818693a7e9cb3b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	S100B CLCA2 SPHKAP SCN2B UNC79	2.48e-05	187	82	5	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP SCN8A UNC79 CNR1 RYR2	2.48e-05	187	82	5	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AREL1 DMXL2 LRSAM1 WDR35 TKTL1	2.48e-05	187	82	5	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KCND3 SPHKAP SCN8A ACTL6B UNC79	2.54e-05	188	82	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 PPP2R5C SCN2B PRMT1 ST6GALNAC4	2.67e-05	190	82	5	a124e1c12af70161b9ead5d677afa660610444ee
ToppCell	Neuroendocrine\|World / Class top	TMEM45B SCN8A SCN9A UPP1 ACTL6B	2.81e-05	192	82	5	0199da3ef9ddb6673e9aa41f346f374838aec182
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP SCN2B SCN8A ACTL6B CNR1	2.88e-05	193	82	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TBC1D8 DMXL2 RGS18 IFI30 FMNL1	2.95e-05	194	82	5	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TBC1D8 DMXL2 RGS18 IFI30 FMNL1	2.95e-05	194	82	5	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	erythropoietic-CD34+_Pro-erythroblast\|erythropoietic / Lineage and Cell class	RGS18 MATK LAPTM4B CTNNBL1 FMNL1	3.02e-05	195	82	5	cd3d8fa6e18c0508cdfb64bb879d90b211badee5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DMXL2 IFI30 UPP1 TKTL1 FMNL1	3.10e-05	196	82	5	a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TUBB1 S100B RGS18 PPP2R5C MATK	3.18e-05	197	82	5	b5b333e98753946793ceb45e2d85c25ef53568b4
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TUBB1 S100B RGS18 PPP2R5C MATK	3.18e-05	197	82	5	4cec48e202f4583c9328d4b722c49ed3471ec173
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_CTL\|Leuk-UTI / Disease, condition lineage and cell class	PPP2R5C KCND3 MATK DDR2 PACSIN3	3.33e-05	199	82	5	b2609f9d716fdd04f35f0da7f8995d28d7df431d
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PPP2R5C MATK TKTL1 ZBTB1 FMNL1	3.33e-05	199	82	5	0902b08e3386e64d7347c186d9ce5b67f2deaabb
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Monocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBC1D8 DMXL2 ATP8B4 RGS18 FMNL1	3.41e-05	200	82	5	fd72fe6565e2f4885481991492d58c323ab1ad40
ToppCell	Lung_Parenchyma-Severe-Myeloid-cDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	S100B ATP8B4 RGS18 IFI30 FMNL1	3.41e-05	200	82	5	9744d53915c8dc9d5e011cbbb0ac7db44c615ce7
ToppCell	Parenchyma_COVID-19-Immune-TX-DCs\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	S100B ATP8B4 RGS18 IFI30 FMNL1	3.41e-05	200	82	5	6237e4b46b196e1d1610b2edc60af4716a6fed25
ToppCell	Lung_Parenchyma-Severe-Myeloid-cDC-DCs-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	S100B ATP8B4 RGS18 IFI30 FMNL1	3.41e-05	200	82	5	b52f7534a5ff504dccc002ebc30836a87e43c123
ToppCell	Lung_Parenchyma-Severe-Myeloid-cDC-DCs\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	S100B ATP8B4 RGS18 IFI30 FMNL1	3.41e-05	200	82	5	cb0ba75be8fb2ec47474559911df80d085c4dbc8
ToppCell	(05)_Ciliated-(2)_48hpi\|(05)_Ciliated / shred by cell type and Timepoint	KANK3 ADAM29 TKTL1 FMNL1	8.14e-05	124	82	4	fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TUBB1 RGS18 KCND3 SLFN14	9.21e-05	128	82	4	a190aa5a6db9c4120f4667af40ac3da2f267d4da
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA2 INSC SCN8A SCN9A	1.20e-04	137	82	4	4dcb15de821439011df1bb0bbd7682d674bd725d
ToppCell	facs-Marrow-B-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA2 INSC SCN8A SCN9A	1.20e-04	137	82	4	c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCell	Fetal_29-31_weeks-Immune-mast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TUBB1 ATP8B4 ACTL6B ATP6V0A2	1.49e-04	145	82	4	dc89d817a9bef24a07e992efdab4136f12ceb399
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KANK3 JAG1 LRSAM1 TMEM150C	1.88e-04	154	82	4	e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD3C KANK3 FBXO47 AMIGO1	1.97e-04	156	82	4	ea9223bb6450b22df11efa1705ab72dab005244a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD3C KANK3 FBXO47 AMIGO1	1.97e-04	156	82	4	586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TUBB1 KCND3 INSC RYR2	1.97e-04	156	82	4	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TUBB1 KCND3 INSC RYR2	1.97e-04	156	82	4	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	E15.5-Hematopoietic-Immune-immune_cell_unspecified\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP8B4 RGS18 IFI30 FMNL1	2.02e-04	157	82	4	4263627911657e788a1d0230690ee434e8a4f9a1
ToppCell	E15.5-Hematopoietic-Immune\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP8B4 RGS18 IFI30 FMNL1	2.02e-04	157	82	4	de689a133863ed74d848eba0a4f392357ac28245
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8B4 RGS18 HIPK1 IFI30	2.02e-04	157	82	4	552fd5d09bbe81f58404ec38166feb30fc84def5
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	TBC1D8 TMEM45B TMEM150C AMIGO1	2.07e-04	158	82	4	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TUBB1 RGS18 KCND3 SLFN14	2.07e-04	158	82	4	944c5fe625f965dd6153dbcbf5577f99ad343983
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS18 SCN2B TMEM150C FMNL1	2.07e-04	158	82	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 MATK IFI30 FMNL1	2.12e-04	159	82	4	cdbccb83af6220bab300dfe56443ff69f6e2043a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS18 SCN2B TMEM150C FMNL1	2.17e-04	160	82	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN8A TKTL1 D2HGDH FMNL1	2.17e-04	160	82	4	ec81814f3a475ba9bc049cb793bf93bc0b650d37
ToppCell	wk_08-11-Hematologic-Meg-ery-Platelet\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TUBB1 RGS18 TKTL1 SLFN14	2.17e-04	160	82	4	e0591f95f3f47ffbe013ebbebf6bed8c7c344732
ToppCell	Influenza_Severe-gd_T\|World / Disease group and Cell class	S100B PPP2R5C MATK DDR2	2.22e-04	161	82	4	b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JAG1 SCN8A PREX2 CNR1	2.28e-04	162	82	4	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FMNL3 CLCA2 SLFN14 PREX2	2.33e-04	163	82	4	7864e966c228282b4b63c43164dba3faba21026d
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBC1D8 RGS18 IFI30 UNC79	2.39e-04	164	82	4	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBC1D8 RGS18 IFI30 UNC79	2.39e-04	164	82	4	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 RGS18 MATK FMNL1	2.39e-04	164	82	4	f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCND3 SPHKAP SCN8A UNC79	2.39e-04	164	82	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RHPN1 TTC29 ACTL6B UNC79	2.44e-04	165	82	4	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	PND14-Immune-Immune_Myeloid-DC-maDC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D8 SCN2B TMEM150C IFI30	2.44e-04	165	82	4	1c3709ac9f96ace1f3b28e1f2f15b4a8d65885ca
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FMNL3 RGS18 SCN9A FMNL1	2.44e-04	165	82	4	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	PND14-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBC1D8 SCN2B TMEM150C IFI30	2.44e-04	165	82	4	fbc7d97e6f30975d35c76a7c97947a34cf5975d2
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TBC1D1 JAG1 CNR1 RYR2	2.44e-04	165	82	4	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHPN1 MATK LRSAM1 DNAH17	2.50e-04	166	82	4	a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCell	facs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHPN1 MATK LRSAM1 DNAH17	2.50e-04	166	82	4	0f641302a6b71c4badaaf20f51162bfc2386b167
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD141+_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	S100B RGS18 PREX2 RYR2	2.50e-04	166	82	4	9f14e3ef19d5903278c040be1c477501237173fa
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV5/7_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATAD3B ATP8B4 MATK ATP6V0A2	2.56e-04	167	82	4	18e336faa2d2429ab49d1c6ae9bbf9923d74aa8d
ToppCell	Dendritic_Cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	S100B ATP8B4 RGS18 FMNL1	2.61e-04	168	82	4	33618e5dbcee31f30afacacc9f6046782c100fb3
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RHPN1 SPHKAP SCN2B RYR2	2.74e-04	170	82	4	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor-MUC5AC+ASCL1+_intermediate_\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TBC1D8 TMEM45B TTC29 DNAH17	2.74e-04	170	82	4	d6e244725b21592c6056b9c443aac090f1eae836
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RHPN1 SPHKAP SCN2B RYR2	2.74e-04	170	82	4	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	S100B RGS18 SBF1 KCND3	2.80e-04	171	82	4	1018d7bd378ce20bee56a77d5851b3538c55098c
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	INSC DDR2 PREX2 RYR2	2.80e-04	171	82	4	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	S100B RGS18 SBF1 KCND3	2.80e-04	171	82	4	6bda333bb751d7835a04f21ac959eea79f2516aa
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	S100B RGS18 SBF1 KCND3	2.80e-04	171	82	4	173bb5318fdbaef6e695b6f9e3e0ff4a5432a1a4
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KANK3 JAG1 UPP1 PREX2	2.80e-04	171	82	4	3112d15f2a28cf4a71992db4971d960716dc1264
ToppCell	343B-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TBC1D8 ATP6V1H AGAP9 ZNF649	2.86e-04	172	82	4	eb199c279fe8a2551121db37e9556893197d33ff
ToppCell	343B-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TBC1D8 ATP6V1H AGAP9 ZNF649	2.86e-04	172	82	4	709c6b77a7a52b873eefb6caca28a41291d384af
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMXL2 ATP8B4 IFI30 FMNL1	2.92e-04	173	82	4	279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBC1D8 RGS18 SCN2B IFI30	2.92e-04	173	82	4	f66aebceb3eb389bc5ff6c0b398d6f4e9959a14f
ToppCell	facs-Lung-EPCAM-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B4 RGS18 IFI30 FMNL1	2.92e-04	173	82	4	50b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	S100B RGS18 KCND3 FMNL1	2.92e-04	173	82	4	73f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHPN1 CLCA2 PACSIN3 PLOD1	3.05e-04	175	82	4	9d082ba0e350162aa6e71b668be074b12a27c7ab
Disease	B Virus Infection	SCN8A SCN9A	2.12e-05	3	79	2	C0037140
Disease	Postherpetic neuralgia	SCN8A SCN9A	2.12e-05	3	79	2	C0032768
Disease	Herpesviridae Infections	SCN8A SCN9A	2.12e-05	3	79	2	C0019372
Disease	neuromuscular disease (implicated_via_orthology)	ATAD3B ATAD3C	4.23e-05	4	79	2	DOID:440 (implicated_via_orthology)
Disease	Muscle Spasticity	ACTL6B CNR1	7.04e-05	5	79	2	C0026838
Disease	glucose metabolism decline measurement, cingulate cortex measurement	TBC1D8 PPP4R3A	2.52e-04	9	79	2	EFO_0007738, EFO_0009392
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN8A SCN9A	3.14e-04	10	79	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN8A SCN9A	3.14e-04	10	79	2	DOID:0080422 (implicated_via_orthology)
Disease	Other specified cardiac arrhythmias	KCND3 SCN2B	3.83e-04	11	79	2	C0348626
Disease	Nodal rhythm disorder	KCND3 SCN2B	3.83e-04	11	79	2	C0264893
Disease	Ectopic rhythm	KCND3 SCN2B	3.83e-04	11	79	2	C1399226
Disease	CARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)	KCND3 SCN2B	3.83e-04	11	79	2	C2748542
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN8A SCN9A	4.59e-04	12	79	2	DOID:0060170 (implicated_via_orthology)
Disease	Brugada Syndrome 1	KCND3 SCN2B	5.42e-04	13	79	2	C4551804
Disease	Hereditary Motor and Sensory-Neuropathy Type II	LRSAM1 SCN9A	5.42e-04	13	79	2	C0270914
Disease	Sinus Node Dysfunction (disorder)	KCND3 SCN2B	7.27e-04	15	79	2	C0428908
Disease	syndrome (implicated_via_orthology)	ATAD3B ATAD3C	1.05e-03	18	79	2	DOID:225 (implicated_via_orthology)
Disease	Disproportionate short stature	DDR2 WDR35 EXT2	1.17e-03	77	79	3	C0878659
Disease	Brugada Syndrome (disorder)	KCND3 SCN2B	1.88e-03	24	79	2	C1142166

Protein segments in the cluster

Peptide	Gene	Start	Entry
FMQNEITCRMEFEEI	ADAM29	166	Q9UKF5
IMAVDRCAFDDMAQL	AMIGO1	146	Q86WK6
LSSVMDFQEDLYCMN	AMIGO1	241	Q86WK6
LEFFTQVMLKCMNEE	CFAP54	1336	Q96N23
EMEMFEFLNICQAHG	AGAP9	56	Q5VTM2
EQEMMENLFDSLCSC	CTNNBL1	306	Q8WYA6
GDFISMQCRELFQEM	ACTL6B	196	O94805
FAEANAVACTLDMVM	CYP2W1	281	Q8TAV3
LFMEMNQKLFDDCTQ	PPP2R5C	396	Q13362
YACNMLTDDMNDVFV	ATP8B4	686	Q8TF62
DMIMAFSVNKANCNE	DMXL2	2661	Q8TDJ6
MAAAEAANCIMENFV	PRMT1	1	Q99873
ALFEVMFSEECIMDV	PPP4R3A	206	Q6IN85
IQEMMTFVQFANDEC	HPF1	271	Q9NWY4
FMTAVDLMEASQLCS	ORC4	296	O43929
IDEQMFEQNCMESSM	KCND3	511	Q9UK17
DEAVFFCNLMDMVEH	MATK	181	P42679
GEANFFTSQMIKDCM	INTS11	116	Q5TA45
QACSSMAEMDERFQQ	LRSAM1	416	Q6UWE0
CMITEYMENGDLNQF	DDR2	651	Q16832
FNCLDDMAQVNMSTD	HIPK1	461	Q86Z02
ALCDNDDTAMAAFMN	ARNTL2	601	Q8WYA1
EFMDDANMCIAIAIS	LAPTM4B	156	Q86VI4
EMNFIIQEGESINCM	LRBA	81	P50851
ALSTNEDMQMQCELF	NFAT5	941	O94916
IFMQAHECMEIVFGT	MAGEA13P	146	A6NCF6
MAFCANIRQQDVFMF	PLOD1	481	Q02809
QFDFVVRMMNCCLQD	SBF1	621	O95248
FVAMESSTFVCMAID	OR56B2P	116	Q8NGI1
NQFACSAIMTVMSVD	MCHR2	116	Q969V1
MVAFLDCMQQFKEEA	BECN2	351	A8MW95
AFQECERMNILTNEM	DNAH17	4231	Q9UFH2
LAFLTIVCMEEFEDM	IFI30	141	P13284
RNEDSNIDFMVACMQ	FMNL3	311	Q8IVF7
IQMNKCTDEEQMFGF	FASTKD1	41	Q53R41
CETNNMMEYVILIEF	CHIC2	141	Q9UKJ5
CFILNNDMSEMELVF	AREL1	611	O15033
EAMMDACVQDFVQQH	ATAD3C	376	Q5T2N8
IQCGENFMDIECFMV	CNR1	96	P21554
NFKEFIDTMMSNTEC	EFCAB13	581	Q8IY85
EDSNIDFMVACMQFI	FMNL1	316	O95466
NVANAFACVIMEMLQ	FBXO47	396	Q5MNV8
LANITFFDTMACEML	INSC	396	Q1MX18
FFDTMACEMLLQLNA	INSC	401	Q1MX18
QEEEDMAVVQRLFCM	KANK3	671	Q6NY19
MIPMECDSFCSDQNE	SCAF11	716	Q99590
MELFVNFCEDTIFEM	RYR2	4186	Q92736
ILSAFEFMDAVCMQL	D2HGDH	306	Q8N465
MEDMEQAFETCQAAE	PACSIN3	221	Q9UKS6
DNCANITFTFNKEMM	JAG1	956	P78504
NIEMESSVFAAMCSA	UPP1	246	Q16831
TDEFSRFMVNQMENE	SPHKAP	1126	Q2M3C7
MISAEDCEFIQRFEM	ATP6V1H	41	Q9UI12
DQMGCEFFNLLIMEQ	SLFN14	561	P0C7P3
TNMLTAEMDNFVCDT	RIF1	2056	Q5UIP0
AEMDNFVCDTVEMST	RIF1	2061	Q5UIP0
LTQMSFFVLFACMDD	OR7E24	116	Q6IFN5
NDMFNFETFGNSMIC	SCN9A	1676	Q15858
FQEFMAFVAMVTTAC	S100B	71	P04271
QQMFDARNTMAACDL	TUBB1	291	Q9H4B7
CVFSQVMNMAAFLAL	TMEM150C	66	B9EJG8
LEQLMMAQAQECVFE	RHPN1	276	Q8TCX5
EAMMDACVQDAVQQY	ATAD3B	551	Q5T9A4
MFMQSLSSVVEFCNA	CLCA2	241	Q9UQC9
SIMFMQSIDSVVEFC	CLCA4	236	Q14CN2
QKDDANLMFITMCFC	TMEM45B	206	Q96B21
ECNNCSEEMFLQFRM	SCN2B	71	O60939
ERMMAYCDQIFQDET	ST6GALNAC4	186	Q9H4F1
METTLLFFSQINMCE	RGS18	1	Q9NS28
QSCIMHVDMDCFFVS	REV1	416	Q9UBZ9
FVSCLDIMYNGEMNE	TBC1D8	901	O95759
VFQCTNEALVDEIMM	TBC1D1	351	Q86TI0
DAHMNCEDIAMNFLV	EXT2	621	Q93063
FDFVTQQAFDIVIMM	SCN8A	1516	Q9UQD0
CAFSEQLMAALNQMF	PREX2	1276	Q70Z35
CLDQDMFKSAIMEEN	ZBTB1	556	Q9Y2K1
CFQQAFDTTVELMSM	TTC29	376	Q8NA56
EACNNNLEMAVTMFL	UBXN7	36	O94888
MSCEFLQQINSMVDF	STRCP1	1196	A6NGW2
LELCTFEEGSQMDNM	ZBTB2	426	Q8N680
CPFFEEMEALMSAQV	ZSCAN29	321	Q8IWY8
TMEQIFMNVAIFEDE	POLR1B	636	Q9H9Y6
EIAQMFVRVGMCEQA	WDR35	861	Q9P2L0
ERFIECFMAEQNMVS	TKTL1	331	P51854
MACEEFNFGEILMTQ	ATP6V0A2	721	Q9Y487
CEDDEMNLNCFILMF	UNC79	791	Q9P2D8
NMVTVAMVAGQCEFA	ZNF649	486	Q9BS31