Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiongalactoside 2-alpha-L-fucosyltransferase activity

FUT1 FUT2

1.06e-053382GO:0008107
GeneOntologyMolecularFunctionalpha-(1,2)-fucosyltransferase activity

FUT1 FUT2

1.06e-053382GO:0031127
GeneOntologyMolecularFunctionATP:phosphate antiporter activity

SLC25A25 SLC25A23

1.06e-053382GO:0140987
GeneOntologyMolecularFunctionacetyltransferase activity

CHAT LCAT BRCA2 EP300

4.47e-05104384GO:0016407
GeneOntologyMolecularFunctionorganophosphate:phosphate antiporter activity

SLC25A25 SLC25A23

7.36e-057382GO:0015315
GeneOntologyMolecularFunctioncytoskeletal protein binding

RHCG ACTC1 BRCA2 CLMN STARD9 EP300 SYNE1 TRPC5 ACTA1

1.72e-041099389GO:0008092
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC4 TRPC5

2.30e-0412382GO:0015279
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC4 TRPC5

3.16e-0414382GO:0070679
GeneOntologyMolecularFunctionATP transmembrane transporter activity

SLC25A25 SLC25A23

3.16e-0414382GO:0005347
GeneOntologyMolecularFunctionfucosyltransferase activity

FUT1 FUT2

3.16e-0414382GO:0008417
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

BRCA2 EP300

3.65e-0415382GO:0010484
GeneOntologyMolecularFunctionprotein antigen binding

EP400 EP300

4.16e-0416382GO:1990405
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC25A25 SLC25A23

8.70e-0423382GO:0005346
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

BRCA2 EP300

8.70e-0423382GO:0010485
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC25A25 SLC25A23

9.48e-0424382GO:0005315
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

CHAT LCAT BRCA2 EP300

1.06e-03238384GO:0016747
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC25A25 SLC25A23

1.11e-0326382GO:0000295
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC25A25 SLC25A23

1.39e-0329382GO:0015216
GeneOntologyMolecularFunctioncytoskeletal motor activity

ACTC1 STARD9 DNAH14

1.46e-03118383GO:0003774
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC25A25 SLC25A23

1.69e-0332382GO:0005452
GeneOntologyMolecularFunctionnucleotide transmembrane transporter activity

SLC25A25 SLC25A23

1.79e-0333382GO:0015215
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC25A25 SLC25A23

2.50e-0339382GO:0015605
GeneOntologyMolecularFunctionhistone acetyltransferase activity

BRCA2 EP300

4.24e-0351382GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

BRCA2 EP300

4.91e-0355382GO:0061733
GeneOntologyMolecularFunctionO-acyltransferase activity

CHAT LCAT

5.64e-0359382GO:0008374
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC25A25 SLC25A23

5.64e-0359382GO:1901505
GeneOntologyMolecularFunctionnucleobase-containing compound transmembrane transporter activity

SLC25A25 SLC25A23

5.64e-0359382GO:0015932
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BRCA2 EP300

5.82e-0360382GO:0034212
GeneOntologyMolecularFunctionmicrotubule motor activity

STARD9 DNAH14

7.85e-0370382GO:0003777
GeneOntologyMolecularFunctionhistone modifying activity

ATM BRCA2 EP300

9.35e-03229383GO:0140993
GeneOntologyMolecularFunctionN-acetyltransferase activity

BRCA2 EP300

9.67e-0378382GO:0008080
GeneOntologyMolecularFunctionmyosin binding

ACTC1 ACTA1

1.14e-0285382GO:0017022
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

RHCG SLC25A25 SLC25A23 TRPC4 TRPC5

1.38e-02758385GO:0015318
GeneOntologyMolecularFunctionacyltransferase activity

CHAT BFAR LCAT BRCA2 EP300

1.51e-02775385GO:0016746
GeneOntologyBiologicalProcessmesenchyme migration

ACTC1 ACTA1 ACTA2

5.75e-085383GO:0090131
GeneOntologyBiologicalProcessskeletal muscle thin filament assembly

ACTC1 ACTA1

6.90e-057382GO:0030240
GeneOntologyBiologicalProcessfucose catabolic process

FUT1 FUT2

1.18e-049382GO:0019317
GeneOntologyBiologicalProcessL-fucose catabolic process

FUT1 FUT2

1.18e-049382GO:0042355
GeneOntologyBiologicalProcessL-fucose metabolic process

FUT1 FUT2

1.47e-0410382GO:0042354
GeneOntologyBiologicalProcessskeletal myofibril assembly

ACTC1 ACTA1

1.80e-0411382GO:0014866
GeneOntologyBiologicalProcessADP transport

SLC25A25 SLC25A23

2.16e-0412382GO:0015866
GeneOntologyBiologicalProcessorganophosphate ester transport

PITPNC1 SLC25A25 SLC25A23 TRPC5

2.20e-04162384GO:0015748
GeneOntologyBiologicalProcessmesenchyme morphogenesis

ACTC1 ACTA1 ACTA2

2.33e-0465383GO:0072132
GeneOntologyBiologicalProcessoligosaccharide metabolic process

FUT1 FUT2 GAA

2.90e-0470383GO:0009311
GeneOntologyBiologicalProcessfucose metabolic process

FUT1 FUT2

3.90e-0416382GO:0006004
GeneOntologyBiologicalProcessregulation of cellular response to heat

ATM EP300

3.90e-0416382GO:1900034
GeneOntologyCellularComponentmicrotubule organizing center attachment site

CLMN SYNE1

1.75e-0411382GO:0034992
GeneOntologyCellularComponentnuclear membrane protein complex

CLMN SYNE1

1.75e-0411382GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

CLMN SYNE1

1.75e-0411382GO:0106094
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

CLMN SYNE1

1.75e-0411382GO:0034993
GeneOntologyCellularComponenthistone acetyltransferase complex

POTEJ EP400 EP300

6.63e-0494383GO:0000123
GeneOntologyCellularComponentlamellipodium

ACTC1 PTPRM ACTA1 ACTA2

7.86e-04230384GO:0030027
GeneOntologyCellularComponentDNA repair complex

ATM BRCA2

7.95e-0423382GO:1990391
GeneOntologyCellularComponentprotein acetyltransferase complex

POTEJ EP400 EP300

8.89e-04104383GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

POTEJ EP400 EP300

1.02e-03109383GO:1902493
GeneOntologyCellularComponentfilopodium

ACTC1 ACTA1 ACTA2

1.44e-03123383GO:0030175
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

POTEJ EP400

1.54e-0332382GO:0043189
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

POTEJ EP400

1.54e-0332382GO:0035267
GeneOntologyCellularComponentintracellular protein-containing complex

CUL7 POTEJ EP400 BRCA2 KLHDC2 EP300 RIC1

1.64e-03972387GO:0140535
GeneOntologyCellularComponentcontractile muscle fiber

ACTC1 SYNE1 ACTA1 ACTA2

1.85e-03290384GO:0043292
GeneOntologyCellularComponentactin filament

ACTC1 POTEJ ACTA1

2.35e-03146383GO:0005884
GeneOntologyCellularComponentnuclear outer membrane

CLMN SYNE1

2.40e-0340382GO:0005640
GeneOntologyCellularComponentH4 histone acetyltransferase complex

POTEJ EP400

3.03e-0345382GO:1902562
GeneOntologyCellularComponentnuclear ubiquitin ligase complex

CUL7 BRCA2

3.59e-0349382GO:0000152
HumanPhenoDyspnea

ACTC1 CHAT BRCA2 EP300 GAA SDHA ACTA1 ACTA2

1.57e-05506148HP:0002094
HumanPhenoRespiratory insufficiency

ACTC1 CHAT CUL7 BRCA2 EP300 SYNE1 GAA SDHA ACTA1 ACTA2

2.64e-059621410HP:0002093
HumanPhenoAbnormal cardiac ventricle morphology

ACTC1 ATM BRCA2 EP300 SYNE1 GAA SDHA ACTA1 ACTA2

4.29e-05780149HP:0001713
HumanPhenoCardiac conduction abnormality

ACTC1 EP300 SYNE1 SDHA ACTA1

5.62e-05167145HP:0031546
HumanPhenoAbnormal thorax morphology

ACTC1 CHAT CUL7 BRCA2 EP300 SYNE1 GAA RIC1 SDHA ACTA1 ACTA2

5.93e-0513281411HP:0000765
HumanPhenoLower extremity joint dislocation

CHAT CUL7 BRCA2 EP300 SYNE1 ACTA1

1.11e-04318146HP:0030311
HumanPhenoNeoplasm of the stomach

ATM BRCA2 EP300 SDHA

1.11e-0498144HP:0006753
HumanPhenoCerebral hemorrhage

GAA SDHA ACTA1 ACTA2

1.35e-04103144HP:0001342
HumanPhenoRespiratory insufficiency due to muscle weakness

CHAT SYNE1 GAA ACTA1

1.35e-04103144HP:0002747
HumanPhenoBenign neoplasm of the central nervous system

ATM BRCA2 EP300 SDHA

1.46e-04105144HP:0100835
HumanPhenoAbnormality of blood circulation

ACTC1 ATM BRCA2 GAA SDHA ACTA1 ACTA2

1.52e-04498147HP:0011028
HumanPhenoInternal hemorrhage

ATM BRCA2 GAA SDHA ACTA1 ACTA2

1.58e-04339146HP:0011029
HumanPhenoNeoplasm of the large intestine

ATM BRCA2 EP300 SDHA

2.00e-04114144HP:0100834
HumanPhenoWeakness of muscles of respiration

CHAT SYNE1 GAA ACTA1

2.14e-04116144HP:0004347
HumanPhenoNeoplasm of the rectum

ATM BRCA2 SDHA

2.34e-0446143HP:0100743
HumanPhenoRespiratory distress

CHAT EP300 GAA SDHA ACTA1

2.37e-04226145HP:0002098
HumanPhenoLipodystrophy

ACTC1 LMF1 SYNE1 SDHA

3.04e-04127144HP:0009125
HumanPhenoAbnormal cerebral vascular morphology

ACTC1 CUL7 GAA SDHA ACTA1 ACTA2

3.33e-04388146HP:0100659
HumanPhenoJoint dislocation

CHAT CUL7 BRCA2 EP300 SYNE1 ACTA1

3.43e-04390146HP:0001373
HumanPhenoGeneralized muscle weakness

CHAT GAA SDHA ACTA1

3.73e-04134144HP:0003324
HumanPhenoAbnormal muscle tissue metabolite concentration

GAA SDHA ACTA1

3.77e-0454143HP:0034370
HumanPhenoAbnormal circulating creatine concentration

ATM BRCA2

3.80e-0411142HP:0012113
HumanPhenoAbnormal subclavian artery morphology

EP300 ACTA2

3.80e-0411142HP:0031251
HumanPhenoRenal neoplasm

ATM BRCA2 EP300 SDHA

4.30e-04139144HP:0009726
HumanPhenoIncreased overbite

EP300 RIC1

4.56e-0412142HP:0011094
HumanPhenoFeeding difficulties in infancy

CHAT EP300 SYNE1 GAA RIC1 SDHA ACTA1

4.65e-04594147HP:0008872
HumanPhenoSpinal rigidity

CHAT SYNE1 ACTA1

4.91e-0459143HP:0003306
HumanPhenoUrinary tract neoplasm

ATM BRCA2 EP300 SDHA

4.92e-04144144HP:0010786
HumanPhenoFlexion contracture

CHAT ATM BRCA2 EP300 SYNE1 RIC1 SDHA ACTA1

5.14e-04817148HP:0001371
HumanPhenoJoint contracture

CHAT ATM BRCA2 EP300 SYNE1 RIC1 SDHA ACTA1

6.41e-04843148HP:0034392
HumanPhenoAbnormal left ventricular function

ACTC1 GAA SDHA ACTA2

6.50e-04155144HP:0005162
HumanPhenoLow weight

ATM CUL7 BRCA2 EP300 SYNE1 SDHA ACTA1

6.51e-04627147HP:0001823
HumanPhenoIntracranial hemorrhage

GAA SDHA ACTA1 ACTA2

6.66e-04156144HP:0002170
HumanPhenoExercise intolerance

ACTC1 GAA SDHA ACTA1

6.66e-04156144HP:0003546
HumanPhenoMuscle fiber atrophy

CHAT SYNE1 ACTA1

7.14e-0467143HP:0100295
HumanPhenoHypertrophic cardiomyopathy

ACTC1 BRCA2 SYNE1 GAA SDHA

7.55e-04290145HP:0001639
HumanPhenoEMG abnormality

ACTC1 CHAT SYNE1 SDHA ACTA1

7.92e-04293145HP:0003457
HumanPhenoAbnormal pattern of respiration

ACTC1 CHAT BRCA2 EP300 GAA SDHA ACTA1 ACTA2

8.12e-04872148HP:0002793
HumanPhenoAbnormal tendon morphology

CHAT ATM BRCA2 EP300 SYNE1 RIC1 SDHA ACTA1

8.32e-04875148HP:0100261
HumanPhenoUterine neoplasm

ATM BRCA2 EP300

8.81e-0472143HP:0010784
HumanPhenoAbnormal muscle fiber morphology

CHAT SYNE1 GAA SDHA ACTA1

9.09e-04302145HP:0004303
HumanPhenoLimb-girdle muscular dystrophy

SYNE1 ACTA1

9.32e-0417142HP:0006785
HumanPhenoMild microcephaly

RIC1 SDHA

9.32e-0417142HP:0040196
HumanPhenoHyperintensity of cerebral white matter on MRI

EP300 GAA ACTA2

9.55e-0474143HP:0030890
HumanPhenoAdult onset

ACTC1 LMF1 LCAT BRCA2 SYNE1 GAA SDHA ACTA1

9.66e-04894148HP:0003581
HumanPhenoAbnormal cardiac ventricular function

ACTC1 GAA SDHA ACTA2

9.85e-04173144HP:0030872
HumanPhenoAbnormal sternum morphology

CHAT CUL7 EP300 SYNE1 ACTA1 ACTA2

9.86e-04474146HP:0000766
HumanPhenoFemale reproductive system neoplasm

ATM BRCA2 EP300

1.03e-0376143HP:0033020
HumanPhenoCardiac diverticulum

ATM BRCA2

1.05e-0318142HP:0100571
HumanPhenoType 1 muscle fiber atrophy

SYNE1 ACTA1

1.05e-0318142HP:0011807
HumanPhenoNeoplasm of the central nervous system

ATM BRCA2 EP300 SDHA

1.10e-03178144HP:0100006
HumanPhenoLeft ventricular noncompaction

ACTC1 SDHA

1.17e-0319142HP:0030682
HumanPhenoAbnormal morphology of left ventricular trabeculae

ACTC1 SDHA

1.17e-0319142HP:0031192
HumanPhenoDilated cardiomyopathy

ACTC1 SYNE1 SDHA ACTA1

1.24e-03184144HP:0001644
HumanPhenoAbnormal heart morphology

EP300 GAA SDHA ACTA2

1.24e-03184144HP:3000001
HumanPhenoNeoplasm of the colon

ATM BRCA2 SDHA

1.24e-0381143HP:0100273
HumanPhenoAbnormal morphology of myocardial trabeculae

ACTC1 SDHA

1.30e-0320142HP:0030681
HumanPhenoAbnormality of the amniotic fluid

CHAT ATM BRCA2 EP300 SYNE1 ACTA1

1.37e-03504146HP:0001560
HumanPhenoCongenital hip dislocation

CHAT CUL7 ACTA1

1.38e-0384143HP:0001374
HumanPhenoClumsiness

SYNE1 SDHA ACTA1

1.48e-0386143HP:0002312
HumanPhenoNeoplasm of the nervous system

ATM BRCA2 EP300 SDHA

1.54e-03195144HP:0004375
HumanPhenoProximal muscle weakness

CHAT SYNE1 GAA SDHA ACTA1

1.56e-03340145HP:0003701
HumanPhenoFatiguable weakness of proximal limb muscles

SYNE1 ACTA1

1.57e-0322142HP:0030200
HumanPhenoMyopathy

ACTC1 CHAT SYNE1 SDHA ACTA1

1.58e-03341145HP:0003198
MousePhenoearly cellular replicative senescence

ELOA2 CUL7 BRCA2 EP300

1.86e-0570324MP:0008008
MousePhenoabnormal cellular replicative senescence

ELOA2 CUL7 BRCA2 EP300

3.17e-0580324MP:0008007
MousePhenoabnormal skeletal muscle fiber morphology

CHAT EP300 SYNE1 GAA ACTA1

1.10e-04212325MP:0003084
MousePhenoovary degeneration

ATM BRCA2

1.81e-049322MP:0013236
MousePhenoabnormal muscle physiology

ACTC1 CHAT PTPRM EP300 SYNE1 GAA TRPC4 ACTA1 ACTA2

2.07e-04954329MP:0002106
MousePhenoabnormal muscle fiber morphology

ACTC1 CHAT EP300 SYNE1 GAA ACTA1

2.76e-04406326MP:0004087
DomainActin_CS

ACTC1 POTEJ ACTA1 ACTA2

2.60e-0816384IPR004001
DomainACTINS_2

ACTC1 POTEJ ACTA1 ACTA2

3.40e-0817384PS00432
DomainActin/actin-like_CS

ACTC1 POTEJ ACTA1 ACTA2

4.37e-0818384IPR020902
DomainACTINS_ACT_LIKE

ACTC1 POTEJ ACTA1 ACTA2

5.52e-0819384PS01132
DomainACTINS_1

ACTC1 ACTA1 ACTA2

4.32e-078383PS00406
DomainActin

ACTC1 POTEJ ACTA1 ACTA2

4.41e-0731384IPR004000
DomainActin

ACTC1 POTEJ ACTA1 ACTA2

4.41e-0731384PF00022
DomainACTIN

ACTC1 POTEJ ACTA1 ACTA2

4.41e-0731384SM00268
DomainGlyco_trans_11

FUT1 FUT2

4.03e-062382IPR002516
DomainGlyco_transf_11

FUT1 FUT2

4.03e-062382PF01531
DomainTRP_dom

TRPC4 TRPC5

6.02e-056382IPR013555
DomainTRP_2

TRPC4 TRPC5

6.02e-056382PF08344
DomainTRPC_channel

TRPC4 TRPC5

8.41e-057382IPR002153
DomainTRP_channel

TRPC4 TRPC5

2.19e-0411382IPR004729
DomainActinin_actin-bd_CS

CLMN SYNE1

9.93e-0423382IPR001589
Domain-

PITPNC1 STARD9

9.93e-04233823.30.530.20
DomainACTININ_2

CLMN SYNE1

9.93e-0423382PS00020
DomainACTININ_1

CLMN SYNE1

9.93e-0423382PS00019
DomainSTART-like_dom

PITPNC1 STARD9

9.93e-0423382IPR023393
DomainHR1_rho-bd

RTKN2 CCDC70

1.17e-0325382IPR011072
DomainMit_carrier

SLC25A25 SLC25A23

1.92e-0332382IPR002067
DomainSOLCAR

SLC25A25 SLC25A23

5.20e-0353382PS50920
DomainMito_carr

SLC25A25 SLC25A23

5.20e-0353382PF00153
Domain-

SLC25A25 SLC25A23

5.20e-03533821.50.40.10
DomainMt_carrier_dom

SLC25A25 SLC25A23

5.20e-0353382IPR023395
DomainMitochondrial_sb/sol_carrier

SLC25A25 SLC25A23

5.20e-0353382IPR018108
DomainCH

CLMN SYNE1

7.73e-0365382SM00033
PathwayWP_STRIATED_MUSCLE_CONTRACTION_PATHWAY

ACTC1 ACTA1 ACTA2

3.52e-0538243M39549
PathwayWP_LACTO_SERIES_SPHINGOLIPID_METABOLISM

FUT1 FUT2

4.15e-056242M46444
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

ACTC1 ACTA1 ACTA2

6.69e-0547243M39829
PathwayREACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING

TRPC4 TRPC5

1.24e-0410242M27330
PathwayWP_NEOLACTO_SERIES_SPHINGOLIPID_METABOLISM

FUT1 FUT2

1.51e-0411242M48314
PathwayWP_HOMOLOGOUS_RECOMBINATION

ATM BRCA2

1.81e-0412242MM15951
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

EP300 TRPC4 ACTA2

2.11e-0469243M48052
PathwayWP_HOMOLOGOUS_RECOMBINATION

ATM BRCA2

2.14e-0413242M39712
PathwayKEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GLOBO_SERIES

FUT1 FUT2

2.50e-0414242M12899
PathwayKEGG_MEDICUS_REFERENCE_P300_P21_CELL_CYCLE_G1_S

ATM EP300

2.88e-0415242M47524
PathwayBIOCARTA_RACC_PATHWAY

TRPC4 TRPC5

2.88e-0415242M22002
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_5

LMF1 LCAT

2.88e-0415242M42552
PathwayWP_GLIOBLASTOMA_SIGNALING

ATM BRCA2 EP300

3.64e-0483243M39637
PathwayREACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS

FUT1 FUT2

3.72e-0417242MM15629
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

ATM EP300

4.18e-0418242MM15342
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_1

LMF1 LCAT

4.18e-0418242M42559
PathwayREACTOME_GLYCOSPHINGOLIPID_BIOSYNTHESIS

FUT1 FUT2

4.67e-0419242MM17075
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

ATM EP300

4.67e-0419242M27639
PathwayREACTOME_GLYCOSPHINGOLIPID_BIOSYNTHESIS

FUT1 FUT2

4.67e-0419242M48041
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

EP300 ACTA2

5.18e-0420242M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

ATM EP300

5.72e-0421242M39593
PathwayBIOCARTA_P53HYPOXIA_PATHWAY

ATM EP300

5.72e-0421242M5202
PathwayREACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS

FUT1 FUT2

5.72e-0421242M27917
PathwayBIOCARTA_ATRBRCA_PATHWAY

ATM BRCA2

6.28e-0422242M9703
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_4

LMF1 LCAT

6.28e-0422242M42574
PathwayBIOCARTA_G2_PATHWAY

ATM EP300

7.49e-0424242M8560
PathwayREACTOME_PLASMA_LIPOPROTEIN_REMODELING

LMF1 LCAT

8.14e-0425242MM15562
PathwayREACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE

ATM BRCA2

8.81e-0426242MM15297
PathwayKEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES

FUT1 FUT2

8.81e-0426242M17377
PathwayREACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA

ATM BRCA2

9.50e-0427242M27586
PathwayREACTOME_TRP_CHANNELS

TRPC4 TRPC5

1.02e-0328242MM14943
PathwayREACTOME_TRP_CHANNELS

TRPC4 TRPC5

1.02e-0328242M27241
PathwayREACTOME_MEIOSIS

ATM BRCA2 SYNE1

1.07e-03120243M529
PathwayREACTOME_PLASMA_LIPOPROTEIN_REMODELING

LMF1 LCAT

1.51e-0334242M27842
PathwayREACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES

ATM BRCA2

1.60e-0335242MM15293
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

ACTC1 ACTA1

1.60e-0335242MM15005
PathwayREACTOME_STRIATED_MUSCLE_CONTRACTION

ACTC1 ACTA1

1.69e-0336242M18647
PathwayREACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES

ATM BRCA2

1.78e-0337242M27583
PathwayWP_MALE_INFERTILITY

ATM BRCA2 EP300

1.84e-03145243M39856
PathwayPID_FOXM1_PATHWAY

BRCA2 EP300

2.08e-0340242M176
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

ACTC1 ACTA1 ACTA2

2.27e-03156243M39475
PathwayREACTOME_REPRODUCTION

ATM BRCA2 SYNE1

2.35e-03158243M26956
PathwayREACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE

ATM BRCA2

2.40e-0343242M27588
PathwayREACTOME_NETRIN_1_SIGNALING

TRPC4 TRPC5

2.52e-0344242M875
PathwayREACTOME_MUSCLE_CONTRACTION

ACTC1 ACTA1 ACTA2

2.66e-03165243MM15026
PathwayPID_DELTA_NP63_PATHWAY

ATM BRCA2

2.87e-0347242M236
PathwayPID_FANCONI_PATHWAY

ATM BRCA2

2.87e-0347242M1
PathwayPID_HES_HEY_PATHWAY

EP300 GAA

2.99e-0348242M288
PathwayREACTOME_DISEASES_OF_DNA_REPAIR

ATM BRCA2

3.37e-0351242M29854
PathwayWP_CCL18_SIGNALING

EP300 ACTA2

3.50e-0352242M42542
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

FUT1 FUT2

3.63e-0353242MM14647
PathwayREACTOME_DNA_DAMAGE_TELOMERE_STRESS_INDUCED_SENESCENCE

ATM EP400

3.77e-0354242MM14904
PathwayWP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM

ATM BRCA2

3.90e-0355242M39598
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

FUT1 FUT2

4.33e-0358242M576
PathwayPID_P53_REGULATION_PATHWAY

ATM EP300

4.48e-0359242M261
PathwayREACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR

ATM BRCA2

4.48e-0359242MM15283
Pubmed

Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.

ACTC1 ACTA1 ACTA2

1.20e-0933837780165
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTC1 ACTA1 ACTA2

2.40e-08638322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTC1 ACTA1 ACTA2

2.40e-0863831540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTC1 ACTA1 ACTA2

2.40e-08638311709093
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTC1 ACTA1 ACTA2

2.40e-0863839971772
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTC1 ACTA1 ACTA2

2.40e-08638310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTC1 ACTA1 ACTA2

2.40e-08638312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTC1 ACTA1 ACTA2

2.40e-08638323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTC1 ACTA1 ACTA2

2.40e-08638319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTC1 ACTA1 ACTA2

2.40e-08638321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTC1 ACTA1 ACTA2

2.40e-0863838661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTC1 ACTA1 ACTA2

2.40e-08638323017337
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTC1 ACTA1 ACTA2

2.40e-08638310074138
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTC1 ACTA1 ACTA2

2.40e-08638323875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTC1 ACTA1 ACTA2

2.40e-0863839841925
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTC1 ACTA1 ACTA2

4.20e-08738317504171
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTC1 ACTA1 ACTA2

4.20e-08738322535526
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTC1 ACTA1 ACTA2

4.20e-08738322465675
Pubmed

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.

ACTC1 ACTA1 ACTA2

4.20e-0873839384381
Pubmed

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.

ACTC1 ACTA1 ACTA2

4.20e-08738330289203
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTC1 ACTA1 ACTA2

4.20e-08738318443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTC1 ACTA1 ACTA2

4.20e-08738322640593
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTC1 ACTA1 ACTA2

6.71e-08838314694110
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTC1 ACTA1 ACTA2

6.71e-08838320147394
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTC1 ACTA1 ACTA2

6.71e-08838323260110
Pubmed

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.

ACTC1 ACTA1 ACTA2

6.71e-08838320096780
Pubmed

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

ACTC1 ACTA1 ACTA2

1.01e-07938312297046
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTC1 ACTA1 ACTA2

1.01e-0793838892894
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTC1 ACTA1 ACTA2

1.01e-07938310556093
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTC1 ACTA1 ACTA2

1.01e-07938318775311
Pubmed

Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.

ACTC1 ACTA1 ACTA2

1.44e-071038321749862
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTC1 ACTA1 ACTA2

1.44e-07103831991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTC1 ACTA1 ACTA2

1.44e-071038323575248
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTC1 ACTA1 ACTA2

1.44e-07103831907279
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTC1 ACTA1 ACTA2

1.97e-071138330962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTC1 ACTA1 ACTA2

1.97e-071138323294842
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTC1 ACTA1 ACTA2

1.97e-071138319639585
Pubmed

FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.

ACTC1 ACTA1 ACTA2

1.97e-071138322207710
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTC1 ACTA1 ACTA2

2.63e-071238323071112
Pubmed

SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.

ACTC1 ACTA1 ACTA2

2.63e-071238331042497
Pubmed

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.

ACTC1 ACTA1 ACTA2

3.42e-071338318400219
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

ACTC1 ACTA1 ACTA2

4.34e-071438321923909
Pubmed

Regulating the functions of the HIV-1 matrix protein.

ACTC1 ACTA1 ACTA2

4.34e-071438317411366
Pubmed

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.

ACTC1 ACTA1 ACTA2

5.43e-071538324598388
Pubmed

Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.

ACTC1 ACTA1 ACTA2

6.67e-071638316638982
Pubmed

Serum response factor is essential for mesoderm formation during mouse embryogenesis.

ACTC1 ACTA1 ACTA2

6.67e-07163839799237
Pubmed

Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.

ACTC1 ACTA1 ACTA2

8.10e-071738317360745
Pubmed

The cleavage of host cell proteins by HIV-1 protease.

ACTC1 ACTA1 ACTA2

8.10e-07173838997639
Pubmed

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.

ACTC1 ACTA1 ACTA2

9.71e-071838324840128
Pubmed

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.

ACTC1 ACTA1 ACTA2

9.71e-071838315929941
Pubmed

Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.

ACTC1 ACTA1 ACTA2

1.15e-061938330700554
Pubmed

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.

ACTC1 ACTA1 ACTA2

1.15e-061938318316483
Pubmed

Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

TRPC4 TRPC5

1.16e-06238234899056
Pubmed

Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

TRPC4 TRPC5

1.16e-06238217593972
Pubmed

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.

ACTC1 ACTA1

1.16e-06238219468071
Pubmed

Two prevalent h alleles in para-Bombay haplotypes among 250,000 Taiwanese.

FUT1 FUT2

1.16e-06238215487706
Pubmed

Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.

ACTC1 ACTA1

1.16e-06238220706863
Pubmed

Two novel alleles on Fucosyltransferase 2 from northern Thai para-Bombay family and computational prediction on mutation effect.

FUT1 FUT2

1.16e-06238234487549
Pubmed

alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.

ACTC1 ACTA1

1.16e-0623821893870
Pubmed

Extreme Response to High-dose Testosterone in BRCA2- and ATM-mutated Prostate Cancer.

ATM BRCA2

1.16e-06238227692705
Pubmed

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.

TRPC4 TRPC5

1.16e-06238226317356
Pubmed

Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis.

FUT1 FUT2

1.16e-06238215213174
Pubmed

Genetic manipulation of blood group carbohydrates alters development and pathfinding of primary sensory axons of the olfactory systems.

FUT1 FUT2

1.16e-06238216884711
Pubmed

A novel capacitative calcium entry channel expressed in excitable cells.

TRPC4 TRPC5

1.16e-0623829687496
Pubmed

The H blood group system.

FUT1 FUT2

1.16e-06238227834485
Pubmed

Identification of the plasticity-relevant fucose-alpha(1-2)-galactose proteome from the mouse olfactory bulb.

FUT1 FUT2

1.16e-06238219527073
Pubmed

A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

ACTC1 ACTA1

1.16e-0623823023046
Pubmed

Missense mutation of FUT1 and deletion of FUT2 are responsible for Indian Bombay phenotype of ABO blood group system.

FUT1 FUT2

1.16e-0623829299444
Pubmed

Point mutations and deletion responsible for the Bombay H null and the Reunion H weak blood groups.

FUT1 FUT2

1.16e-0623829745152
Pubmed

Sequence analysis of the human fucosyltransferase 1 and 2 genes in Tibetan blood donors: identification of three novel alleles.

FUT1 FUT2

1.16e-06238224527852
Pubmed

Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes.

FUT1 FUT2

1.16e-06238214967068
Pubmed

Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer.

ATM BRCA2

1.16e-06238234533610
Pubmed

Genomic analysis of para-Bombay individuals in south-eastern China: the possibility of linkage and disequilibrium between FUT1 and FUT2.

FUT1 FUT2

1.16e-06238225761312
Pubmed

Deficiency of reproductive tract alpha(1,2)fucosylated glycans and normal fertility in mice with targeted deletions of the FUT1 or FUT2 alpha(1,2)fucosyltransferase locus.

FUT1 FUT2

1.16e-06238211713270
Pubmed

[Molecular genetic analysis of FUT1 and FUT2 gene in para-Bombay Chinese: a novel FUT1 allele is identified].

FUT1 FUT2

1.16e-06238217922418
Pubmed

Macrophages regulate expression of α1,2-fucosyltransferase genes in human endometrial epithelial cells.

FUT1 FUT2

1.16e-06238222053055
Pubmed

Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.

ACTC1 ACTA2

1.16e-06238210686609
Pubmed

Widespread gene conversion of alpha-2-fucosyltransferase genes in mammals.

FUT1 FUT2

1.16e-06238219533213
Pubmed

[Analysis on FUT1 and FUT2 gene of 10 para-Bombay individuals in China].

FUT1 FUT2

1.16e-06238215476160
Pubmed

Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.

ACTC1 ACTA1

1.16e-0623823075543
Pubmed

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

TRPC4 TRPC5

1.16e-06238222457348
Pubmed

Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress.

FUT1 FUT2

1.16e-06238221172308
Pubmed

Conserved gating elements in TRPC4 and TRPC5 channels.

TRPC4 TRPC5

1.16e-06238223677990
Pubmed

The human chromosome 19 linkage group FUT1 (H), FUT2 (SE), LE, LU, PEPD, C3, APOC2, D19S7 and D19S9.

FUT1 FUT2

1.16e-0623821763885
Pubmed

Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response.

ATM EP400

1.16e-06238227814680
Pubmed

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.

TRPC4 TRPC5

1.16e-06238232033274
Pubmed

Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical Outcomes.

ATM BRCA2

1.16e-06238237126020
Pubmed

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

TRPC4 TRPC5

1.16e-06238217624425
Pubmed

A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.

ACTC1 ACTA1

1.16e-0623822731651
Pubmed

A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.

ACTC1 ACTA1

1.16e-0623826897014
Pubmed

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

TRPC4 TRPC5

1.16e-06238230038709
Pubmed

Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.

ACTC1 ACTA1 ACTA2

1.58e-062138320230754
Pubmed

Myocardial Mycn is essential for mouse ventricular wall morphogenesis.

ACTC1 ACTA1 ACTA2

1.58e-062138323063798
Pubmed

Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.

ACTC1 ACTA1 ACTA2

1.83e-062238316526095
Pubmed

Essential and supporting host cell factors for HIV-1 budding.

ACTC1 ACTA1 ACTA2

2.10e-062338322004035
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

ACTC1 ACTA1 ACTA2

3.07e-062638324742657
Pubmed

Comparison of the three rat GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferases FTA, FTB and FTC.

FUT1 FUT2

3.48e-06338211179967
Pubmed

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

TRPC4 TRPC5

3.48e-06338228790178
Pubmed

Is olaparib cost effective in metastatic castration-resistant prostate cancer patients with at least one favorable gene mutation in BRCA1, BRCA2 or ATM?

ATM BRCA2

3.48e-06338234517749
Pubmed

BRCA2 is required for neurogenesis and suppression of medulloblastoma.

ATM BRCA2

3.48e-06338217476307
InteractionPFN3 interactions

ACTC1 POTEJ ACTA2

6.78e-0710373int:PFN3
InteractionACTG2 interactions

ACTC1 POTEJ ACTA1 ACTA2

1.92e-0649374int:ACTG2
InteractionPOTEJ interactions

ACTC1 POTEJ ACTA1 ACTA2

2.44e-0652374int:POTEJ
InteractionCAP2 interactions

ACTC1 POTEJ ACTA1 ACTA2

6.39e-0666374int:CAP2
InteractionNEXN interactions

ACTC1 CUL7 ACTA1 ACTA2

2.29e-0591374int:NEXN
InteractionABRA interactions

ACTC1 ACTA1 ACTA2

3.90e-0536373int:ABRA
InteractionPOTEI interactions

ACTC1 POTEJ ACTA1 ACTA2

4.03e-05105374int:POTEI
InteractionERRFI1 interactions

ACTC1 ATM ACTA1 ACTA2

4.33e-05107374int:ERRFI1
InteractionGANAB interactions

CUL7 PTPRM EP300 GAA SDHA ACTA1

5.13e-05368376int:GANAB
InteractionACTA1 interactions

ACTC1 CUL7 POTEJ EP300 ACTA1 ACTA2

5.36e-05371376int:ACTA1
InteractionDNASE1 interactions

ACTA1 ACTA2

6.85e-057372int:DNASE1
InteractionPOTEE interactions

ACTC1 POTEJ ACTA1 ACTA2

1.04e-04134374int:POTEE
InteractionHOXB3 interactions

EP300 SDHA

1.17e-049372int:HOXB3
InteractionPLEC interactions

ACTC1 CUL7 BRCA2 SLC25A25 ACTA1 ACTA2

1.21e-04430376int:PLEC
InteractionMSH6 interactions

ACTC1 ATM CUL7 PTPRM EP300

1.30e-04271375int:MSH6
InteractionANGPTL8 interactions

ACTA1 ACTA2

1.46e-0410372int:ANGPTL8
InteractionSLCO1B3 interactions

BRCA2 ACTA2

1.46e-0410372int:SLCO1B3
InteractionUGT1A7 interactions

LMF1 FUT1 SEL1L3

1.56e-0457373int:UGT1A7
InteractionSCIN interactions

ACTC1 ACTA1 ACTA2

1.64e-0458373int:SCIN
InteractionWASH8P interactions

ACTC1 ACTA2

1.79e-0411372int:WASH8P
InteractionACTBL2 interactions

ACTC1 CUL7 POTEJ ACTA1 ACTA2

1.96e-04296375int:ACTBL2
InteractionGC interactions

ACTC1 ACTA1 ACTA2

2.00e-0462373int:GC
InteractionSELENOP interactions

EP400 EP300

2.14e-0412372int:SELENOP
InteractionPPP1R1A interactions

ACTA1 ACTA2

2.53e-0413372int:PPP1R1A
InteractionPCYT1B interactions

ACTA1 ACTA2

2.53e-0413372int:PCYT1B
InteractionTPSAB1 interactions

ATM BRCA2

2.94e-0414372int:TPSAB1
InteractionPDIA6 interactions

ACTC1 CUL7 PTPRM EP300 SDHA

3.10e-04327375int:PDIA6
InteractionFBXO40 interactions

ACTC1 ACTA2

3.39e-0415372int:FBXO40
InteractionNAA80 interactions

ACTC1 ACTA2

3.39e-0415372int:NAA80
InteractionTERF2 interactions

ATM BRCA2 EP300 SYNE1 TRPC5

3.71e-04340375int:TERF2
InteractionHSD17B4 interactions

BFAR CUL7 SUSD1 SDHA

3.96e-04190374int:HSD17B4
InteractionDMAP1 interactions

ACTC1 EP400 BRCA2 ACTA1

4.04e-04191374int:DMAP1
InteractionFEN1 interactions

ACTC1 ATM BRCA2 EP300

4.21e-04193374int:FEN1
InteractionTMSB4X interactions

ACTC1 ACTA1 ACTA2

4.25e-0480373int:TMSB4X
InteractionREG3A interactions

ACTC1 ACTA2

4.38e-0417372int:REG3A
InteractionNHEJ1 interactions

ATM BRCA2

4.38e-0417372int:NHEJ1
InteractionSTAT2 interactions

EP400 EP300 GAA

4.40e-0481373int:STAT2
InteractionACTA2 interactions

ACTC1 POTEJ EP300 ACTA1 ACTA2

4.52e-04355375int:ACTA2
CytobandEnsembl 112 genes in cytogenetic band chr1q42

PCNX2 DNAH14 ACTA1

1.04e-03240383chr1q42
Cytoband19q13.3

FUT1 FUT2

2.12e-038238219q13.3
CytobandEnsembl 112 genes in cytogenetic band chr13q13

BRCA2 TRPC4

2.12e-0382382chr13q13
GeneFamilyActins

ACTC1 ACTA1 ACTA2

5.26e-086263929
GeneFamilyFucosyltransferases|Blood group antigens

FUT1 FUT2

1.54e-0413262434
GeneFamilyTransient receptor potential cation channels

TRPC4 TRPC5

7.35e-0428262249
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100

ACTC1 ACTA1 ACTA2

1.34e-0526383gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100

ACTC1 ACTA1 ACTA2

1.68e-0528383gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_500

ACTC1 ACTA1 ACTA2

8.65e-0548383gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_200

ACTC1 ACTA1 ACTA2

9.78e-0550383gudmap_developingLowerUrinaryTract_P1_bladder_B_200_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_100

ACTC1 ACTA1

1.11e-049382gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_100_k3
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

ACTC1 PITPNC1 PTPRM CLMN TRPC4

7.36e-07200385c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ACTC1 PITPNC1 PTPRM CLMN TRPC4

7.36e-07200385117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ACTC1 PITPNC1 PTPRM CLMN TRPC4

7.36e-07200385d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

PCNX2 RHCG SLC25A25 RIC1

6.46e-06142384e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FUT1 PITPNC1 BRCA2 STARD9

1.01e-05159384c960df9e4fa980401941866b5081facac4590b4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATM BRCA2 RIC1 SEL1L3

1.09e-051623848ed9149ff53b285591354057055d072b203a47c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATM BRCA2 RIC1 SEL1L3

1.09e-051623847a05b05a33e1309fb5c0a8171db105ae68491815
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

1.57e-051783846ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNC1 CLMN TRPC4 ACTA2

1.61e-05179384111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLMN STARD9 TRPC4 ACTA2

1.68e-05181384451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

1.75e-0518338404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

1.79e-051843842ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

1.87e-05186384948815663c212c4311329d503b5991cbbbff9808
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLMN STARD9 TRPC4 ACTA2

1.95e-05188384ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

1.95e-051883848de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

1.99e-0518938478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

2.03e-051903843f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PITPNC1 PTPRM TRPC4 TRPC5

2.03e-05190384305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

2.03e-0519038439ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PITPNC1 CLMN TRPC4 ACTA2

2.03e-05190384a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CLMN STARD9 TRPC4 ACTA2

2.03e-051903844eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CLMN STARD9 TRPC4 ACTA2

2.03e-051903847be4341e2909101d756f14031c21e705eb45e69a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

2.03e-051903848c9c230a509afaeee50644153974a5642b01a2b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CLMN STARD9 TRPC4 ACTA2

2.08e-0519138404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

2.12e-051923840003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACTC1 CLMN ACTA1 ACTA2

2.16e-051933845ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACTC1 CLMN ACTA1 ACTA2

2.16e-051933845260ac95a15cc43a19909badad0c7e3854da920d
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TTC39B ATM PITPNC1 SYNE1

2.16e-05193384a594f89a18273797506287d9e22f72abe53e4920
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4 TRPC5

2.16e-05193384c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RHCG RTKN2 BRCA2 ACTA2

2.16e-05193384516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B RTKN2 ATM SYNE1

2.16e-051933849337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RTKN2 PTPRM SYNE1 DNAH14

2.21e-0519438453f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNC1 PTPRM STARD9 SYNE1

2.21e-05194384a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RTKN2 PTPRM SYNE1 DNAH14

2.25e-051953849406866f99555198a9be311fbd65751b70f35446
ToppCellCTRL|World / Disease state, Lineage and Cell class

TTC39B SUSD1 PTPRM GAA

2.25e-05195384cad77cdc6e0aa0875eff5ecd3805a6cf056d729d
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / disease group, cell group and cell class

ATM PITPNC1 PTPRM SYNE1

2.30e-051963841bc1ec3351319c5d2daa0808cf161a7327e1758e
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

ACTC1 CLMN ACTA1 ACTA2

2.30e-05196384541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLMN STARD9 TRPC4 ACTA2

2.34e-0519738441dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLMN STARD9 TRPC4 ACTA2

2.34e-05197384f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B RTKN2 ATM SYNE1

2.34e-0519738457ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TTC39B ATM STARD9 SYNE1

2.34e-05197384e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ACTC1 TRPC4 ACTA1 ACTA2

2.44e-05199384534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLMN STARD9 TRPC4 ACTA2

2.44e-05199384929f809579368201331d9099d8904b6e3c41797b
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLMN STARD9 TRPC4 ACTA2

2.44e-05199384854628ce91068093c14bd4d45ba38c41469f3549
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PITPNC1 PTPRM TRPC4 TRPC5

2.48e-052003844a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

ACTC1 PITPNC1 PTPRM TRPC4

2.48e-052003841276bfa911fddada4235e12e3081baa53164574b
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CLMN STARD9 TRPC4 ACTA2

2.48e-05200384d70bad979299615fcba707ba21296020918705e6
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1|Neuronal / cells hierarchy compared to all cells using T-Statistic

PITPNC1 PTPRM TRPC4 TRPC5

2.48e-05200384fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PITPNC1 PTPRM TRPC4 TRPC5

2.48e-05200384c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CLMN STARD9 TRPC4 ACTA2

2.48e-0520038438c21ec379005f688df33aea65237a063c476c2e
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-pDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUSD1 KLRF2 SEL1L3

1.81e-04129383454bae525f6db3d0dd6347d2a2c3ea9dda9cd212
ToppCellLPS_only-Myeloid-Dendritic_cells-pDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUSD1 KLRF2 SEL1L3

2.06e-041353830afe232aa1a1e6c37a5b3183b67d7fa07e0ea791
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLC25A23 TRPC4 SEL1L3

2.20e-04138383096c0c8ed396a27d29cca94e2e15099b64129c57
ToppCellCOVID-19-kidney-Mito-rich_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNC1 PTPRM SYNE1

2.55e-04145383afed661aef990edb8e7012ab67ace56443520c9f
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUSD1 KLRF2 SEL1L3

2.92e-041523830c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRM TRPC4 TRPC5

2.92e-041523838ff5a178a8f3550d89a003c0858820aab3773386
ToppCellInfluenza_Severe-Treg|Influenza_Severe / Disease group and Cell class

TTC39B RTKN2 FUT2

3.04e-0415438377845bcb243aa1b1f1ca00f9ef2ae1b4d1bd3696
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUSD1 KLRF2 SEL1L3

3.40e-04160383dee756a2dc9725520d439e7273c489c2284015d8
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

PITPNC1 STARD9 SYNE1

3.46e-04161383b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FUT1 FUT2 CLMN

3.52e-0416238325323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FUT1 FUT2 CLMN

3.52e-041623833dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FUT1 FUT2 CLMN

3.52e-041623830a7138266054ea5954649c8b61ef93905d56b068
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ATM SYNE1 ACTA2

3.52e-0416238319395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CLMN ACTA1 ACTA2

3.59e-0416338351dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 SYNE1 TRPC4

3.65e-04164383f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ATM FUT2 SYNE1

3.65e-04164383b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

RHCG ACTC1 ACTA2

3.72e-04165383531804467601e1ee1f771cffa21501f6d464ae10
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 TRPC4 ACTA2

3.72e-041653839de841c1c95967c562720feba930246debc626fd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 TRPC4 ACTA2

3.72e-04165383a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 TRPC4 ACTA2

3.72e-04165383cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTC1 ACTA1 ACTA2

3.78e-041663839a341dc7b756252caeaac1e934384911c880a634
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTC1 ACTA1 ACTA2

3.78e-04166383390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCellTuft-tuft-1|World / Class top

PITPNC1 SLC25A23 SEL1L3

3.92e-041683838ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellICU-NoSEP-Lymphocyte-T_NK-CD4_CTL|ICU-NoSEP / Disease, Lineage and Cell Type

PITPNC1 PTPRM SYNE1

3.99e-04169383cbda36f32bd78322dcfe303a44413415d08e5ea3
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTC1 SLC25A23 ACTA2

4.06e-04170383da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTC1 SLC25A23 ACTA2

4.06e-04170383cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellInfluenza_Severe-gd_T|Influenza_Severe / Disease group and Cell class

PITPNC1 STARD9 SYNE1

4.06e-0417038359009c5a504ea8c6b4f6697299db219fd5edf7d6
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACTC1 BFAR SLC25A23

4.06e-04170383070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRPC5 KLRF2 SEL1L3

4.13e-041713834fd2c7977c512c51507f055fc74b111c0228ed8b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 SYNE1 TRPC4

4.20e-04172383553701349444eb366df3c11f54bb093434f153c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STARD9 SYNE1 TRPC4

4.20e-0417238308a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG TTC39B SUSD1

4.27e-041733830bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTC1 ACTA1 ACTA2

4.27e-04173383ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTC1 ACTA1 ACTA2

4.27e-04173383b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNC1 CLMN TRPC4

4.34e-041743838393f0b43c767839c1630bcb952d62b42efc788d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTKN2 CLMN DNAH14

4.34e-04174383ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRM TRPC4 TRPC5

4.41e-041753839d797888edb39fd12fd9cfc698a42b7bed19a5b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RTKN2 ELOA2 BRCA2

4.41e-04175383876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PITPNC1 PTPRM TRPC4

4.49e-04176383322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTC1 PTPRM TRPC4

4.49e-04176383682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTKN2 CLMN DNAH14

4.49e-0417638340993c41c1017b53039a337174fc56632b278609
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACTC1 ACTA1 ACTA2

4.49e-041763834ed73c73972334f6dc4229920205547823252fa0
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMF1 FUT1 ACTA1

4.49e-041763832e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STARD9 TRPC4 ACTA2

4.56e-04177383452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLMN STARD9 TRPC4

4.64e-04178383185b44700f06ec58b3c09c80520502166c965fd6
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG ACTA1 ACTA2

4.64e-0417838356b19f9c9585538fb8a4c3eea2d132b254cf11ef
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMF1 FUT1 GAA

4.64e-04178383b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

PITPNC1 STARD9 TRPC4

4.72e-04179383342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RTKN2 BRCA2 KLRF2

4.72e-0417938388d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CLMN TRPC4 ACTA2

4.72e-04179383a69ad6912b5c10bb9f9d800f724c792341e9bab1
ComputationalMuscle genes.

ACTC1 ACTA1 ACTA2

7.23e-0537243MODULE_512
ComputationalGenes in the cancer module 387.

ACTC1 ACTA1 ACTA2

1.68e-0449243MODULE_387
ComputationalGenes in the cancer module 329.

ACTC1 ACTA1 ACTA2

1.90e-0451243MODULE_329
DrugAC1L1CWO

FUT2 GAA ACTA1 ACTA2

2.98e-0735374CID000002095
DrugNsc687160

ACTC1 ACTA1 ACTA2

3.17e-0618373CID005459290
Drugtolytoxin

ACTC1 ACTA1 ACTA2

3.76e-0619373CID006440827
Drugm2-19

ACTC1 ACTA1 ACTA2

3.76e-0619373CID000079129
DrugAC1MNW2N

ACTC1 FUT2 ACTA1 ACTA2

5.01e-0670374CID003359490
DrugAC1L8NVR

ACTC1 ACTA1 ACTA2

5.15e-0621373CID000384633
DrugNSC312786

ACTC1 ACTA1 ACTA2

5.15e-0621373CID000329495
DrugCoA group

ACTC1 CHAT LCAT EP300 SDHA ACTA1 ACTA2

5.39e-06433377CID000000317
DrugAC1L1DXE

ACTC1 CHAT TRPC4 TRPC5 ACTA1 ACTA2

8.05e-06299376CID000002548
DrugAC1L1BDQ

ACTC1 TRPC4 TRPC5 ACTA1 ACTA2

8.56e-06173375CID000001394
Drugplakin

ACTC1 SYNE1 ACTA1 ACTA2

9.43e-0682374CID000018752
DrugCID5288653

ACTC1 ACTA1 ACTA2

1.26e-0528373CID005288653
DrugAC1L22RD

ACTC1 SDHA ACTA1 ACTA2

1.43e-0591374CID000065183
DrugIsoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; MCF7; HT_HG-U133A

PCNX2 CUL7 SLC25A23 EP300 ACTA2

1.49e-051943752824_DN
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA

ATM CUL7 EP400 CLMN SEL1L3

1.49e-051943751060_UP
DrugEnzyme Activators

EP300 ACTA2

1.54e-054372ctd:D020536
Drugazaspiracid

ACTC1 ACTA1 ACTA2

1.56e-0530373CID006451158
DrugHarmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; PC3; HT_HG-U133A

PCNX2 ATM ELOA2 BRCA2 ACTA2

1.60e-051973756623_DN
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A

LMF1 ATM FUT1 BRCA2 ACTA2

1.64e-051983752069_DN
DrugDioxybenzone [131-53-3]; Up 200; 16.4uM; MCF7; HT_HG-U133A

CHAT ELOA2 CUL7 SLC25A23 TRPC4

1.68e-051993756478_UP
DrugEdrophonium chloride [116-38-1]; Down 200; 19.8uM; PC3; HT_HG-U133A

PCNX2 ELOA2 FUT1 BRCA2 ACTA2

1.68e-051993756655_DN
DrugAC1L1HS4

ACTC1 ACTA1 ACTA2

1.90e-0532373CID000004267
Drugsulphoxide

ACTC1 SYNE1 ACTA1 ACTA2

2.15e-05101374CID000008442
DrugN,N'-p-phenylenedimaleimide

ACTC1 ACTA1 ACTA2

2.28e-0534373CID000076765
Drug1,N6-ethenoadenosine 5'-diphosphate

ACTC1 ACTA1 ACTA2

2.28e-0534373CID000001312
Drug4-acetylpyridine

CHAT SYNE1

2.56e-055372CID000014282
DrugIrganox 1076

FUT1 FUT2

2.56e-055372CID000016386
DrugAC1NSKFN

ACTC1 ACTA1 ACTA2

2.72e-0536373CID005311324
Drugepsilon-ATP

ACTC1 ACTA1 ACTA2

4.04e-0541373CID000162262
DrugAC1L8FNU

ACTC1 ACTA1 ACTA2

5.00e-0544373CID000425429
DrugCefotetanum [inn-latin]

ACTC1 ATM GAA

5.71e-0546373CID000050614
Drugpyrene

ACTC1 LCAT ACTA1 ACTA2

5.97e-05131374CID000031423
DrugNpCaM

ACTC1 ACTA1 ACTA2

6.50e-0548373CID000122259
DrugAC1Q6LQU

ACTC1 ACTA1 ACTA2

6.50e-0548373CID000072380
DrugNSC60597

ACTC1 SDHA ACTA1 ACTA2

7.73e-05140374CID000003327
DrugNSC106399

ACTC1 ACTA1 ACTA2

7.80e-0551373CID000002887
DrugBtzo-tdmap

SYNE1 GAA

9.18e-059372CID000124335
Drugselinan

SYNE1 SDHA

9.18e-059372CID000035524
DrugML-9

ACTC1 TRPC5 ACTA1 ACTA2

9.33e-05147374CID000004217
Drug3-methylhistidine

ACTC1 ACTA1 ACTA2

9.78e-0555373CID000064969
DrugCarbachol

CHAT TRPC4 TRPC5

1.03e-0456373ctd:D002217
DrugSodium Fluoride

ACTC1 ATM LCAT STARD9 EP300 SDHA ACTA1 ACTA2

1.03e-04933378ctd:D012969
Drugdihydrocytochalasin B

ACTC1 ACTA1 ACTA2

1.15e-0458373CID000003064
Drugglycine propionyl carnitine

ATM ACTA2

1.15e-0410372ctd:C000588486
Drugthryroxine

ACTC1 ATM GAA ACTA1 ACTA2

1.22e-04302375CID000000853
Drug2-aminoethoxydiphenyl borate

TRPC4 TRPC5 ACTA2

1.33e-0461373ctd:C109986
Drugoryzalin

ACTC1 ACTA1 ACTA2

1.47e-0463373CID000029393
DrugAC1L2HAX

ATM SYNE1

1.68e-0412372CID000020942
Drug5-IAF

ACTC1 ACTA1 ACTA2

1.68e-0466373CID000123822
DrugEmodin

BFAR ATM ACTA1 ACTA2

1.75e-04173374ctd:D004642
Drug5'-N-ethylcarboxamidoadenosine

ACTC1 SYNE1 ACTA1 ACTA2

1.79e-04174374CID000104795
DrugAC1L1ERT

ACTC1 ACTA1 ACTA2

1.92e-0469373CID000002920
Drugzinc chromate

ATM BRCA2

1.98e-0413372ctd:C023616
Drugcopper cyanide

SYNE1 SDHA

1.98e-0413372CID000011009
Drugcaged ATP

ACTC1 ACTA1 ACTA2

2.01e-0470373CID000123806
DrugL-Carnosine

ACTC1 ACTA1 ACTA2

2.27e-0473373CID000009369
Drugsodium methoxide

KLHDC2 SYNE1

2.31e-0414372CID010942334
DrugATCA

ATM ACTA1

2.31e-0414372CID000042485
DrugLawesson's reagent

SYNE1 TRPC5

2.31e-0414372CID000087949
DrugPregnenolone [145-13-1]; Up 200; 12.6uM; MCF7; HT_HG-U133A

ATM ELOA2 FUT2 TRPC5

2.35e-041873742856_UP
DrugC3H2N2O3S

ACTC1 ACTA1 ACTA2

2.37e-0474373CID000448652
DrugAC1LD8HW

ACTC1 ACTA1 ACTA2

2.46e-0475373CID000644061
DrugNSC611747

ACTC1 CHAT TRPC4 ACTA1 ACTA2

2.49e-04352375CID000002534
DrugBenzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ATM CUL7 CLMN EP300

2.55e-041913746839_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A

LMF1 ELOA2 SYNE1 ACTA2

2.66e-041933742675_DN
DrugSIRIUS

ACTC1 ACTA1 ACTA2

2.66e-0477373CID000091750
Drug1-oleoyl-2-acetylglycerol

TRPC4 TRPC5

2.66e-0415372ctd:C038237
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A

ATM CUL7 EP400 CLMN

2.71e-041943741670_DN
DrugAlthiazide [5588-16-9]; Up 200; 10.4uM; HL60; HT_HG-U133A

LMF1 CUL7 CCDC70 ACTA1

2.71e-041943742527_UP
DrugBuflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ATM SLC25A23 CLMN ACTA2

2.71e-041943743274_DN
DrugIsoconazole [27523-40-6]; Down 200; 9.6uM; PC3; HT_HG-U133A

PCNX2 LMF1 EP400 BRCA2

2.82e-041963742056_DN
DrugTrapidil [15421-84-8]; Down 200; 19.4uM; HL60; HT_HG-U133A

LMF1 FUT2 SLC25A23 GAA

2.82e-041963743136_DN
DrugColistin sulfate [1264-72-8]; Up 200; 3uM; MCF7; HT_HG-U133A

ACTC1 LMF1 ATM SLC25A23

2.82e-041963742851_UP
DrugAC1L9EF8

ACTC1 ACTA1 ACTA2

2.87e-0479373CID000443315
DrugCefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A

ATM EP400 SLC25A23 CLMN

2.87e-041973747186_DN
DrugTHIP Hydrochloride; Down 200; 22.6uM; HL60; HT_HG-U133A

CUL7 FUT2 SLC25A23 GAA

2.87e-041973743132_DN
DrugTrimipramine maleate salt [521-78-8]; Down 200; 9.8uM; HL60; HT_HG-U133A

PCNX2 TRPC4 TRPC5 ACTA2

2.87e-041973743004_DN
DrugMepenzolate bromide [76-90-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

LMF1 ATM SLC25A23 CLMN

2.87e-041973743829_DN
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

PCNX2 LMF1 FUT1 SYNE1

2.87e-041973746180_UP
Drugkinin 9

ACTC1 PTPRM TRPC5 ACTA1 ACTA2

2.87e-04363375CID000006026
DrugCyclopenthiazide [742-20-1]; Up 200; 10.6uM; HL60; HT_HG-U133A

CUL7 SLC25A23 GAA TRPC5

2.93e-041983742905_UP
DrugHarmol hydrochloride monohydrate [40580-83-4]; Up 200; 15.8uM; PC3; HT_HG-U133A

ELOA2 CUL7 BRCA2 SLC25A23

2.93e-041983747320_UP
DrugFolinic acid calcium salt [6035-45-6]; Down 200; 7.8uM; HL60; HT_HG-U133A

PCNX2 LMF1 ELOA2 SLC25A23

2.93e-041983742579_DN
DrugNitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A

LMF1 ATM CUL7 SLC25A23

2.93e-041983742303_DN
DrugHalofantrine hydrochloride [36167-63-2]; Down 200; 7.4uM; HL60; HT_HG-U133A

FUT2 SLC25A23 SYNE1 GAA

2.93e-041983743130_DN
DrugLY-171,883; Up 200; 1uM; MCF7; HG-U133A

LMF1 FUT2 BRCA2 CCDC70

2.98e-04199374222_UP
DrugNitrofural [59-87-0]; Up 200; 20.2uM; MCF7; HT_HG-U133A

ATM ELOA2 SYNE1 TRPC5

2.98e-041993743320_UP
DrugMephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A

ELOA2 SYNE1 TRPC5 ACTA1

2.98e-041993743580_UP
DrugAcetazolamide [59-66-5]; Down 200; 18uM; PC3; HT_HG-U133A

LMF1 FUT1 SLC25A23 SYNE1

2.98e-041993741808_DN
DrugXylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A

LMF1 EP400 SLC25A23 SEL1L3

2.98e-041993747020_DN
DrugSerotonin hydrochloride [153-98-0]; Down 200; 18.8uM; HL60; HT_HG-U133A

LMF1 CUL7 SLC25A23 SYNE1

2.98e-041993742449_DN
DrugGriseofulvin [126-07-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ELOA2 CUL7 BRCA2 TRPC5

2.98e-041993744687_DN
DrugWP871

GAA SDHA

3.04e-0416372CID000002006
DrugSulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A

CHAT ELOA2 TRPC4 ACTA2

3.04e-042003743667_UP
Drugmethenamine silver

ACTC1 CHAT ACTA1 ACTA2

3.10e-04201374CID000004101
DrugAC1OAGGW

ACTC1 TRPC5 ACTA1 ACTA2

3.22e-04203374CID006857364
DrugGalactosamine

ATM LCAT ACTA2

3.32e-0483373ctd:D005688
DrugBXL628

ACTC1 ACTA1

3.44e-0417372ctd:C487049
Drugformamide

ACTC1 ACTA1 ACTA2

3.56e-0485373CID000000713
Drugbumetanide

RHCG ACTC1 ACTA1 ACTA2

3.59e-04209374CID000002471
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTC1 ACTA1 ACTA2

9.30e-088363DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTC1 ACTA1 ACTA2

9.30e-088363DOID:0081112 (implicated_via_orthology)
DiseaseMoyamoya disease (implicated_via_orthology)

ACTC1 ACTA1 ACTA2

9.30e-088363DOID:13099 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTC1 ACTA1 ACTA2

9.30e-088363DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTC1 ACTA1 ACTA2

1.99e-0710363DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTC1 ACTA1 ACTA2

1.99e-0710363DOID:13832 (implicated_via_orthology)
DiseaseCardiomyopathy, Dilated

ACTC1 ATM SDHA ACTA1

3.49e-0748364C0007193
DiseaseBombay phenotype

FUT1 FUT2

1.45e-062362cv:C1859408
DiseaseBOMBAY PHENOTYPE

FUT1 FUT2

1.45e-062362616754
Diseaseinfertility (implicated_via_orthology)

ATM BRCA2

3.03e-057362DOID:5223 (implicated_via_orthology)
DiseaseCardiomyopathy, Familial Idiopathic

ACTC1 ATM SDHA

3.14e-0550363C1449563
DiseaseHypertrophic Cardiomyopathy

ACTC1 GAA ACTA1

4.66e-0557363C0007194
Diseasenicotine dependence (implicated_via_orthology)

TRPC4 TRPC5

9.48e-0512362DOID:0050742 (implicated_via_orthology)
DiseaseBenign tumor of pancreas

BRCA2 EP300

1.12e-0413362C0347284
DiseasePancreatic carcinoma

BRCA2 EP300

2.44e-0419362C0235974
DiseasePancreatic Neoplasm

ATM BRCA2 EP300

2.49e-04100363C0030297
DiseaseMalignant neoplasm of pancreas

ATM BRCA2 EP300

2.64e-04102363C0346647
DiseaseAdenocarcinoma of prostate

ATM BRCA2

2.71e-0420362C0007112
Diseaseserum carcinoembryonic antigen measurement

FUT1 FUT2

2.71e-0420362EFO_0005760
DiseaseBREAST CANCER

ATM BRCA2

3.00e-0421362114480
DiseaseMammary Carcinoma, Human

ATM BRCA2 EP300 SYNE1 ACTA2

4.18e-04525365C4704874
DiseaseMammary Neoplasms, Human

ATM BRCA2 EP300 SYNE1 ACTA2

4.18e-04525365C1257931
DiseaseMammary Neoplasms

ATM BRCA2 EP300 SYNE1 ACTA2

4.25e-04527365C1458155
DiseaseLeft Ventricular Hypertrophy

GAA ACTA1

4.27e-0425362C0149721
DiseaseBreast Carcinoma

ATM BRCA2 EP300 SYNE1 ACTA2

4.67e-04538365C0678222
DiseaseMalignant tumor of breast

ATM BRCA2

4.98e-0427362cv:C0006142
DiseaseBreast neoplasm

ATM BRCA2

4.98e-0427362cv:C1458155
DiseaseFamilial cancer of breast

ATM BRCA2

4.98e-0427362cv:C0346153
Diseasecholine measurement

TTC39B LCAT FUT2

5.36e-04130363EFO_0010116
DiseaseBreast Cancer, Familial

ATM BRCA2

6.16e-0430362C0346153
DiseasePrimary familial dilated cardiomyopathy

ACTC1 SDHA

6.16e-0430362cv:C0340427
Diseasecholesteryl esters to total lipids in large LDL percentage

TTC39B LCAT

6.58e-0431362EFO_0022249
Diseasephospholipid measurement

TTC39B LCAT FUT2

6.66e-04140363EFO_0004639
DiseaseMalignant neoplasm of urinary bladder

ATM BRCA2 EP300

6.79e-04141363C0005684
Diseaseneurodegenerative disease (implicated_via_orthology)

SDHA TRPC4 TRPC5

7.37e-04145363DOID:1289 (implicated_via_orthology)
DiseasePrimary dilated cardiomyopathy

ACTC1 SDHA

7.92e-0434362cv:C0007193
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

TTC39B LMF1 LCAT

8.61e-04153363EFO_0004611, EFO_0020946
Diseaseendometrial cancer (is_implicated_in)

ATM BRCA2

8.88e-0436362DOID:1380 (is_implicated_in)
Diseaseduodenal ulcer

FUT2 PITPNC1

8.88e-0436362EFO_0004607
DiseaseHypercholesterolemia

LMF1 LCAT

1.04e-0339362C0020443
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

TTC39B LMF1 BRCA2

1.09e-03166363EFO_0004530, EFO_0004611
DiseaseNeoplasm of uncertain or unknown behavior of breast

BRCA2 EP300

1.15e-0341362C0496956
DiseaseBreast adenocarcinoma

BRCA2 EP300

1.15e-0341362C0858252

Protein segments in the cluster

PeptideGeneStartEntry
QYVDDIWLMFNNAWL

EP300

1116

Q09472
HWDYLLEEMQWMATD

EP400

811

Q96L91
WDDMEKIWHHTFYNE

ACTA1

81

P68133
WDDMEKIWHHSFYNE

ACTA2

81

P62736
LWEEERAFWMENNGH

CCDC70

191

Q6NSX1
WWNDFMVLACYNIND

RIC1

546

Q4ADV7
ELWDLSEAWMQANYD

ELOA2

461

Q8IYF1
HLMWFERLYVWLQCF

PCNX2

1176

A6NKB5
YWVHWHMLEILGFEE

CUL7

421

Q14999
EELHYQAAWRNMQWD

ATM

2096

Q13315
VTFQGNLWMWIDEHF

KLRF2

141

D3W0D1
YQLIAEFAWDWLEVH

BFAR

341

Q9NZS9
YNHYRWIIWKLAAME

BRCA2

2621

P51587
RIPWQNYHLNDWMEE

FUT2

121

Q10981
EDFEWTRHLQYKWNE

DNAH14

1096

Q0VDD8
LAWWEDMVAEFHDQV

GAA

496

P10253
RMNDLHYLNLDTWEW

KLHDC2

241

Q9Y2U9
FADLHFEEGWYMWLQ

LCAT

306

P04180
QETIYDFWRMVWHEN

PTPRM

976

P28827
WRELQLHDWMSEEYA

FUT1

141

P19526
LQKWMEAFWQHFFDL

RTKN2

381

Q8IZC4
KDHQVCLEWNMGYIW

SEL1L3

216

Q68CR1
HEALEEALQSMWFWV

SYNE1

2626

Q8NF91
LGNMEEDNWRWHFYD

SDHA

111

P31040
NWDDMEKIWHHTFYN

POTEJ

741

P0CG39
WNDWQALMEHYSVDI

STARD9

451

Q9P2P6
WDDMEKIWHHTFYNE

ACTC1

81

P68032
MAAHEWDWFQREELI

CLMN

1

Q96JQ2
ANWVSEYWLNDMYLN

CHAT

191

P28329
TMTIDWNEWRDYHLL

SLC25A25

131

Q6KCM7
HLCYWELMWINVFQQ

TTC39B

431

Q5VTQ0
DMEEMYLFHIWGQRW

SUSD1

516

Q6UWL2
HRQAFAWVDEWYDMT

PITPNC1

216

Q9UKF7
QWALLMQGWFHFLQD

RHCG

101

Q9UBD6
MTIDWQEWRDHFLLH

SLC25A23

131

Q9BV35
GFTEYIHDWWNLMDF

TRPC5

426

Q9UL62
LQDYIHDWWNLMDFV

TRPC4

426

Q9UBN4
MWFAAFQTYEHNDWI

LMF1

466

Q96S06