Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylserine binding	ANXA8L1 ADGRB1 ANXA8 ASAP1 SYT13	2.37e-04	73	152	5	GO:0001786
GeneOntologyMolecularFunction	transporter activity	ABCC3 ABCC1 NOX5 ESYT1 PKD1L1 ATG2A PKD1L2 AQP1 AQP5 PANX3 SLC16A12 STARD5 SLC7A1 TMEM120A SLC11A1 ABCB9 SLC35A4 SV2A LRP2 ATP11C DISP2 UNC80	3.08e-04	1289	152	22	GO:0005215
GeneOntologyMolecularFunction	pyrroline-5-carboxylate reductase activity	PYCR1 PYCR2	3.42e-04	4	152	2	GO:0004735
GeneOntologyMolecularFunction	modified amino acid binding	ANXA8L1 ADGRB1 ANXA8 CPS1 ASAP1 SYT13	3.45e-04	122	152	6	GO:0072341
Domain	GPS	PKD1L1 ADGRB1 ADGRB3 PKD1L2 CELSR1 ADGRF3	4.53e-07	36	154	6	PS50221
Domain	GPS	PKD1L1 ADGRB1 ADGRB3 PKD1L2 CELSR1 ADGRF3	5.36e-07	37	154	6	IPR000203
Domain	GPS	ADGRB1 ADGRB3 PKD1L2 CELSR1 ADGRF3	8.19e-06	34	154	5	SM00303
Domain	GPS	ADGRB1 ADGRB3 PKD1L2 CELSR1 ADGRF3	9.49e-06	35	154	5	PF01825
Domain	ARM-type_fold	SMG1 ATR CIP2A UBR4 UNC45A MEI1 LYST PIK3C2G TERB1 ULK4 DIAPH3 XPO7	2.51e-05	339	154	12	IPR016024
Domain	AnnexinVIII	ANXA8L1 ANXA8	6.75e-05	2	154	2	IPR009115
Domain	HRM	ADGRB1 ADGRB3 CELSR1 ADGRF3	7.80e-05	28	154	4	PF02793
Domain	GAIN_dom_N	ADGRB1 ADGRB3 CELSR1	8.64e-05	11	154	3	IPR032471
Domain	GAIN	ADGRB1 ADGRB3 CELSR1	8.64e-05	11	154	3	PF16489
Domain	GPCR_2_brain_angio_inhib	ADGRB1 ADGRB3	2.02e-04	3	154	2	IPR008077
Domain	-	PYCR1 PYCR2	2.02e-04	3	154	2	1.10.3730.10
Domain	P5CR_dimer	PYCR1 PYCR2	2.02e-04	3	154	2	PF14748
Domain	Pellino	PELI2 PELI1	2.02e-04	3	154	2	PF04710
Domain	P5CR_dimer	PYCR1 PYCR2	2.02e-04	3	154	2	IPR029036
Domain	Pellino_fam	PELI2 PELI1	2.02e-04	3	154	2	IPR006800
Domain	PI3/4_kinase_CS	SMG1 ATR PIK3C2G	2.33e-04	15	154	3	IPR018936
Domain	-	SMG1 ATR PIK3C2G	2.85e-04	16	154	3	1.10.1070.11
Domain	PI3Kc	SMG1 ATR PIK3C2G	2.85e-04	16	154	3	SM00146
Domain	GPCR_2_extracellular_dom	ADGRB1 ADGRB3 CELSR1 ADGRF3	3.22e-04	40	154	4	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRB1 ADGRB3 CELSR1 ADGRF3	3.22e-04	40	154	4	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRB1 ADGRB3 CELSR1 ADGRF3	3.22e-04	40	154	4	PS50227
Domain	P5CR	PYCR1 PYCR2	4.01e-04	4	154	2	PS00521
Domain	Pyrroline-COOH_reductase	PYCR1 PYCR2	4.01e-04	4	154	2	IPR000304
Domain	RetinoicA-induced_16-like	FHIP1B FHIP1A	4.01e-04	4	154	2	IPR019384
Domain	RAI16-like	FHIP1B FHIP1A	4.01e-04	4	154	2	PF10257
Domain	Multidrug-R_assoc	ABCC3 ABCC1	4.01e-04	4	154	2	IPR005292
Domain	REJ	PKD1L1 PKD1L2	4.01e-04	4	154	2	PS51111
Domain	REJ_dom	PKD1L1 PKD1L2	4.01e-04	4	154	2	IPR014010
Domain	PI3_PI4_kinase	SMG1 ATR PIK3C2G	4.10e-04	18	154	3	PF00454
Domain	PI3_4_KINASE_1	SMG1 ATR PIK3C2G	4.10e-04	18	154	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 ATR PIK3C2G	4.10e-04	18	154	3	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 ATR PIK3C2G	4.10e-04	18	154	3	IPR000403
Domain	PI3_4_KINASE_3	SMG1 ATR PIK3C2G	4.10e-04	18	154	3	PS50290
Domain	ARM-like	SMG1 ATR CIP2A DAXX UNC45A MEI1 TERB1 ULK4 XPO7	4.12e-04	270	154	9	IPR011989
Domain	GATase	CPS1 GMPS	6.65e-04	5	154	2	PF00117
Domain	FATC	SMG1 ATR	6.65e-04	5	154	2	PF02260
Domain	7tm_2	ADGRB1 ADGRB3 CELSR1 ADGRF3	7.62e-04	50	154	4	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRB1 ADGRB3 CELSR1 ADGRF3	7.62e-04	50	154	4	PS00650
Domain	ABC_membrane	ABCC3 ABCC1 ABCB9	9.80e-04	24	154	3	PF00664
Domain	GATASE_TYPE_1	CPS1 GMPS	9.91e-04	6	154	2	PS51273
Domain	GATASE	CPS1 GMPS	9.91e-04	6	154	2	IPR017926
Domain	PKD/REJ-like	PKD1L1 PKD1L2	9.91e-04	6	154	2	IPR002859
Domain	FAT	SMG1 ATR	9.91e-04	6	154	2	PS51189
Domain	FATC	SMG1 ATR	9.91e-04	6	154	2	PS51190
Domain	REJ	PKD1L1 PKD1L2	9.91e-04	6	154	2	PF02010
Domain	FATC_dom	SMG1 ATR	9.91e-04	6	154	2	IPR003152
Domain	PIK_FAT	SMG1 ATR	9.91e-04	6	154	2	IPR014009
Domain	FATC	SMG1 ATR	9.91e-04	6	154	2	SM01343
Domain	HormR	ADGRB1 ADGRB3 CELSR1	1.11e-03	25	154	3	SM00008
Domain	AAA	ABCC3 ABCC1 WRNIP1 ABCB9 SNRNP200 DYNC1H1	1.25e-03	144	154	6	SM00382
Domain	AAA+_ATPase	ABCC3 ABCC1 WRNIP1 ABCB9 SNRNP200 DYNC1H1	1.25e-03	144	154	6	IPR003593
Domain	ProC_N	PYCR1 PYCR2	1.38e-03	7	154	2	IPR028939
Domain	F420_oxidored	PYCR1 PYCR2	1.38e-03	7	154	2	PF03807
Domain	GPCR_2_secretin-like	ADGRB1 ADGRB3 CELSR1 ADGRF3	1.51e-03	60	154	4	IPR000832
Domain	GPCR_2-like	ADGRB1 ADGRB3 CELSR1 ADGRF3	1.51e-03	60	154	4	IPR017981
Domain	ABC_TM1F	ABCC3 ABCC1 ABCB9	1.55e-03	28	154	3	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCC1 ABCB9	1.55e-03	28	154	3	IPR011527
Domain	G_PROTEIN_RECEP_F2_4	ADGRB1 ADGRB3 CELSR1 ADGRF3	1.61e-03	61	154	4	PS50261
Domain	ZF_SWIM	ZSWIM5 ZSWIM6	2.34e-03	9	154	2	PS50966
Domain	Znf_SWIM	ZSWIM5 ZSWIM6	2.34e-03	9	154	2	IPR007527
Domain	MIP_CS	AQP1 AQP5	2.91e-03	10	154	2	IPR022357
Domain	-	CPS1 GMPS	2.91e-03	10	154	2	3.40.50.880
Domain	PKD_channel	PKD1L1 PKD1L2	3.54e-03	11	154	2	PF08016
Domain	PKD1_2_channel	PKD1L1 PKD1L2	3.54e-03	11	154	2	IPR013122
Domain	Class_I_gatase-like	CPS1 GMPS	4.22e-03	12	154	2	IPR029062
Domain	ANX	ANXA8L1 ANXA8	4.96e-03	13	154	2	SM00335
Domain	Annexin_repeat_CS	ANXA8L1 ANXA8	4.96e-03	13	154	2	IPR018252
Domain	Annexin	ANXA8L1 ANXA8	4.96e-03	13	154	2	PF00191
Domain	Annexin_repeat	ANXA8L1 ANXA8	4.96e-03	13	154	2	IPR018502
Domain	ANNEXIN	ANXA8L1 ANXA8	4.96e-03	13	154	2	PS00223
Domain	-	ANXA8L1 ANXA8	4.96e-03	13	154	2	1.10.220.10
Domain	ABC_transporter_CS	ABCC3 ABCC1 ABCB9	4.99e-03	42	154	3	IPR017871
Domain	-	CARMIL1 TLR9 LRRC43 LRIG2 LRRC14B NOD1 LRRC1 LRRC41	5.22e-03	321	154	8	3.80.10.10
Domain	F-box-like	FBXO48 FBXL22 FBXO7	5.68e-03	44	154	3	PF12937
Domain	Annexin	ANXA8L1 ANXA8	5.76e-03	14	154	2	IPR001464
Domain	MIP	AQP1 AQP5	5.76e-03	14	154	2	PF00230
Domain	MIP	AQP1 AQP5	5.76e-03	14	154	2	PS00221
Domain	L_dom-like	CARMIL1 TLR9 LRRC43 LRIG2 LRRC14B NOD1 LRRC1 LRRC41	5.93e-03	328	154	8	IPR032675
Domain	-	AQP1 AQP5	6.61e-03	15	154	2	1.20.1080.10
Domain	FH2	FMN2 DIAPH3	6.61e-03	15	154	2	PS51444
Domain	Aquaporin-like	AQP1 AQP5	6.61e-03	15	154	2	IPR023271
Domain	FH2_Formin	FMN2 DIAPH3	6.61e-03	15	154	2	IPR015425
Domain	FH2	FMN2 DIAPH3	6.61e-03	15	154	2	PF02181
Domain	MIP	AQP1 AQP5	6.61e-03	15	154	2	IPR000425
Domain	FH2	FMN2 DIAPH3	6.61e-03	15	154	2	SM00498
Domain	ABC_tran	ABCC3 ABCC1 ABCB9	7.25e-03	48	154	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCC1 ABCB9	7.25e-03	48	154	3	PS50893
Domain	Leu-rich_rpt	CARMIL1 TLR9 LRRC43 LRIG2 NOD1 LRRC1 LRRC41	7.31e-03	271	154	7	IPR001611
Domain	ABC_TRANSPORTER_1	ABCC3 ABCC1 ABCB9	7.68e-03	49	154	3	PS00211
Domain	ABC_transporter-like	ABCC3 ABCC1 ABCB9	8.12e-03	50	154	3	IPR003439
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCC3 MAN2B1 ESYT1 UBR4 SFI1 PLXND1 ATG2A ANKHD1 FHIP1B LYST EML3 GRAMD2A SLC7A1 DIP2A CDK5R1 CELSR1 FLCN ULK4 NLE1 DISP2 DYNC1H1	3.38e-08	1105	158	21	35748872
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ESYT1 CIP2A UBR4 FASTKD5 UNC45A TMEM33 LRIG2 NBAS DIP2A OXA1L FAM193A SYNE2 LRRC1 DHPS PYCR1 NLE1 BOLA2 DIAPH3 PYCR2 SNRNP200 NBR1 LRRC41	1.13e-06	1487	158	22	33957083
Pubmed	Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI.	RIPK1 PELI1 DAPK1	7.57e-06	9	158	3	33052227
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	SMG1 CARMIL1 ZSWIM6 LYST TMEM120A MYO15B FAM193A FBXO7 ULK4 ATP11C FHIP1A UNC80	9.17e-06	552	158	12	10737800
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ESYT1 CIP2A UBR4 WRNIP1 PPP2R3B UNC45A ANKHD1 GMPS LRIG2 LRRC1 DHPS PYCR1 BOLA2 DIAPH3 PYCR2 SNRNP200	1.02e-05	974	158	16	28675297
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB1 ADGRB3 CELSR1 ADGRF3	1.51e-05	33	158	4	25713288
Pubmed	Polycystin-1L2 is a novel G-protein-binding protein.	PKD1L1 PKD1L2	2.05e-05	2	158	2	15203210
Pubmed	Analyses of the interaction of WRNIP1 with Werner syndrome protein (WRN) in vitro and in the cell.	WRN WRNIP1	2.05e-05	2	158	2	16769258
Pubmed	TaqI polymorphisms at the annexin VIII locus (ANX8).	ANXA8L1 ANXA8	2.05e-05	2	158	2	1364010
Pubmed	Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.	ANXA8L1 ANXA8	2.05e-05	2	158	2	29306076
Pubmed	Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle.	ATR WRN	2.05e-05	2	158	2	12629512
Pubmed	Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping.	PELI2 PELI1	2.05e-05	2	158	2	11306823
Pubmed	Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.	ANXA8L1 ANXA8	2.05e-05	2	158	2	21344395
Pubmed	Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.	ANXA8L1 ANXA8	2.05e-05	2	158	2	16203777
Pubmed	Annexins: from structure to function.	ANXA8L1 ANXA8	2.05e-05	2	158	2	11917092
Pubmed	The expression of aquaporin 1 and 5 in uterine leiomyomata in premenopausal women: a preliminary study.	AQP1 AQP5	2.05e-05	2	158	2	22472942
Pubmed	Gene-gene interactions lead to higher risk for development of type 2 diabetes in a Chinese Han population: a prospective nested case-control study.	GCKR G6PC2	2.05e-05	2	158	2	30055620
Pubmed	Use of aquaporins 1 and 5 levels as a diagnostic marker in mild-to-moderate adult-onset asthma.	AQP1 AQP5	2.05e-05	2	158	2	26823734
Pubmed	Increased aquaporin 1 and 5 membrane expression in the lens epithelium of cataract patients.	AQP1 AQP5	2.05e-05	2	158	2	27497833
Pubmed	Tanshinone IIA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and AQP5 expression in lung.	AQP1 AQP5	2.05e-05	2	158	2	21244858
Pubmed	Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.	ANXA8L1 ANXA8	2.05e-05	2	158	2	24769558
Pubmed	Expression of aquaporins in the lungs of mice with acute injury caused by LPS treatment.	AQP1 AQP5	2.05e-05	2	158	2	24879973
Pubmed	Effect of down-regulation of aquaporins in human corneal endothelial and epithelial cell lines.	AQP1 AQP5	2.05e-05	2	158	2	20806077
Pubmed	R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1.	WRN WRNIP1	2.05e-05	2	158	2	35163467
Pubmed	Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling.	AQP1 AQP5	2.05e-05	2	158	2	11891232
Pubmed	Reduced lung water transport rate associated with downregulation of aquaporin-1 and aquaporin-5 in aged mice.	AQP1 AQP5	2.05e-05	2	158	2	19215235
Pubmed	Annexins: linking Ca2+ signalling to membrane dynamics.	ANXA8L1 ANXA8	2.05e-05	2	158	2	15928709
Pubmed	Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney.	AQP1 AQP5	2.05e-05	2	158	2	12096051
Pubmed	Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.	ANXA8L1 ANXA8	2.05e-05	2	158	2	25803307
Pubmed	Anti-asthmatic agents alleviate pulmonary edema by upregulating AQP1 and AQP5 expression in the lungs of mice with OVA-induced asthma.	AQP1 AQP5	2.05e-05	2	158	2	22226856
Pubmed	A novel protein interacts with the Werner's syndrome gene product physically and functionally.	WRN WRNIP1	2.05e-05	2	158	2	11301316
Pubmed	MD-2: the Toll 'gatekeeper' in endotoxin signalling.	RIPK1 PELI2 PELI1 TLR9 NOD1	2.27e-05	74	158	5	15276183
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	COL12A1 RIPK1 WRN NIF3L1 DAPK1 CPS1 NUDT9 AQP5 KCTD17 SLC7A1 ISOC2 OXA1L SV2A CPT1C NLE1 CMKLR1 MED27 SYT13	2.58e-05	1293	158	18	15342556
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	ABCC1 RIPK1 WRNIP1 FASTKD5 TLR9 ANKHD1 KCTD17 SNRNP200	4.89e-05	283	158	8	21903422
Pubmed	Phenotype analysis of aquaporin-8 null mice.	AQP1 AQP5	6.13e-05	3	158	2	15647389
Pubmed	Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG.	AQP1 AQP5	6.13e-05	3	158	2	19273840
Pubmed	Expression of aquaporin-1, aquaporin-3, and aquaporin-5 correlates with nodal metastasis in colon cancer.	AQP1 AQP5	6.13e-05	3	158	2	25721378
Pubmed	WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.	ATR WRN	6.13e-05	3	158	2	22159421
Pubmed	The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.	ABCC3 ABCC1	6.13e-05	3	158	2	12628490
Pubmed	Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes.	GCKR G6PC2	6.13e-05	3	158	2	35657990
Pubmed	Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.	ABCC3 ABCC1	6.13e-05	3	158	2	18799096
Pubmed	PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.	PYCR1 PYCR2	6.13e-05	3	158	2	26733354
Pubmed	Specific expression of annexin A8 in adult murine stratified epithelia.	ANXA8L1 ANXA8	6.13e-05	3	158	2	17082908
Pubmed	The expression of water channel proteins during human salivary gland development: a topographic study of aquaporins 1, 3 and 5.	AQP1 AQP5	6.13e-05	3	158	2	28766180
Pubmed	Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.	PYCR1 PYCR2	6.13e-05	3	158	2	24930674
Pubmed	Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).	GCKR G6PC2	6.13e-05	3	158	2	22508271
Pubmed	In situ fluorescence measurement of tear film [Na+], [K+], [Cl-], and pH in mice shows marked hypertonicity in aquaporin-5 deficiency.	AQP1 AQP5	6.13e-05	3	158	2	19136711
Pubmed	Prevention and therapy of hepatocellular carcinoma by vaccination with TM4SF5 epitope-CpG-DNA-liposome complex without carriers.	TLR9 STAT4	6.13e-05	3	158	2	22427965
Pubmed	Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.	ABCC3 ABCC1	6.13e-05	3	158	2	15886284
Pubmed	Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1).	ADGRB1 ADGRB3	6.13e-05	3	158	2	9533023
Pubmed	The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes.	ABCC3 CPS1	6.13e-05	3	158	2	35008510
Pubmed	Expression of brain-specific angiogenesis inhibitor 3 (BAI3) in normal brain and implications for BAI3 in ischemia-induced brain angiogenesis and malignant glioma.	ADGRB1 ADGRB3	6.13e-05	3	158	2	15225653
Pubmed	Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.	ABCC3 ABCC1	6.13e-05	3	158	2	17494643
Pubmed	Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels.	AQP1 AQP5	6.13e-05	3	158	2	10400615
Pubmed	AQP1, AQP5, Bcl-2 and p16 in pharyngeal squamous cell carcinoma.	AQP1 AQP5	6.13e-05	3	158	2	26074259
Pubmed	Vascular anticoagulant beta: a novel human Ca2+/phospholipid binding protein that inhibits coagulation and phospholipase A2 activity. Its molecular cloning, expression and comparison with VAC-alpha.	ANXA8L1 ANXA8	6.13e-05	3	158	2	2530088
Pubmed	Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice.	AQP1 AQP5	6.13e-05	3	158	2	10856128
Pubmed	Direct recording and molecular identification of the calcium channel of primary cilia.	PKD1L1 PKD1L2	6.13e-05	3	158	2	24336289
Pubmed	[Expression of ATP-binding Cassette Proteins Pgp, MRP1, and MRP3 in Malignant and Benign Ovarian Lesions].	ABCC3 ABCC1	6.13e-05	3	158	2	27739315
Pubmed	Expression, genomic structure and mapping of the thymus specific protease prss16: a candidate gene for insulin dependent diabetes mellitus susceptibility.	PRSS16 LYST	6.13e-05	3	158	2	12144812
Pubmed	Functional specialization in proline biosynthesis of melanoma.	PYCR1 PYCR2	6.13e-05	3	158	2	23024808
Pubmed	Induction of multidrug resistance proteins MRP1 and MRP3 and gamma-glutamylcysteine synthetase gene expression by nonsteroidal anti-inflammatory drugs in human colon cancer cells.	ABCC3 ABCC1	6.13e-05	3	158	2	11820781
Pubmed	Aquaporin-dependent water permeation at the mouse ocular surface: in vivo microfluorimetric measurements in cornea and conjunctiva.	AQP1 AQP5	6.13e-05	3	158	2	15557451
Pubmed	Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance.	AQP1 LRP2	6.13e-05	3	158	2	25270072
Pubmed	Genetic analysis of Pycr1 and Pycr2 in mice.	PYCR1 PYCR2	6.13e-05	3	158	2	33734376
Pubmed	Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.	ABCC3 ABCC1	6.13e-05	3	158	2	17845218
Pubmed	Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney.	AQP1 LRP2	6.13e-05	3	158	2	10662735
Pubmed	ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.	ABCC3 ABCC1	6.13e-05	3	158	2	21799180
Pubmed	TonEBP regulates the hyperosmotic expression of aquaporin 1 and 5 in the intervertebral disc.	AQP1 AQP5	6.13e-05	3	158	2	33542263
Pubmed	The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways.	SMG1 ATR	6.13e-05	3	158	2	15279777
Pubmed	Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population.	STAT4 ULK4	6.13e-05	3	158	2	33833419
Pubmed	Identification and localization of aquaporin water channels in human salivary glands.	AQP1 AQP5	6.13e-05	3	158	2	11408278
Pubmed	Expression patterns of the aquaporin gene family during renal development: influence of genetic variability.	AQP1 AQP5 LRP2	8.45e-05	19	158	3	19367412
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CTU2 COL12A1 ZMPSTE24 MAN2B1 ESYT1 UBR4 NIF3L1 UNC45A ANKHD1 ARHGEF17 TMEM33 GMPS SYNE2 NLE1 DIAPH3 NBR1 DYNC1H1	9.14e-05	1297	158	17	33545068
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	ABCC3 ABCC1 SLC7A1 LRP2	9.37e-05	52	158	4	26590417
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	DAXX OXA1L OASL DIAPH3 PYCR2 DYNC1H1	9.85e-05	161	158	6	32572027
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ESYT1 LRIG2 SV2A SNRNP200 XPO7	1.01e-04	101	158	5	9872452
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 OR1M1 ZMPSTE24 WDR4 ZSWIM5 UBR4 LRRC43 LYST ABCB9 SUGCT SYNE2 PYCR1 NLE1 BOLA2 ATP11C DIAPH3 G6PC2 PYCR2	1.04e-04	1442	158	18	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM5 ZSWIM6 FHIP1B ARHGEF17 ASAP1 SV2A DISP2 DYNC1H1 XPO7	1.09e-04	407	158	9	12693553
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	ESYT1 ATG2A LYST LRIG2 NBAS SV2A SYNE2 LRP2 FMN2 FLCN	1.11e-04	504	158	10	34432599
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SMG1 ABCC3 ABCC1 ZMPSTE24 CIP2A DAPK1 OXA1L OASL PYCR1 PYCR2 NBR1 SYT13	1.18e-04	719	158	12	35337019
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ABCC3 EPC2 UBR4 OXGR1 FASTKD5 ZSWIM6 INO80D KCTD17 C2orf72 GMPS NBAS SLC7A1 NOD1 FAM193A FLCN DIAPH3 LRRC41	1.20e-04	1327	158	17	32694731
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	ABCC3 ABCC1 SLC16A12 SLC7A1 LRP2	1.22e-04	105	158	5	30280653
Pubmed	Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk.	GCKR G6PC2	1.22e-04	4	158	2	19533084
Pubmed	Efficacy of Resistance to Francisella Imparted by ITY/NRAMP/SLC11A1 Depends on Route of Infection.	TLR9 SLC11A1	1.22e-04	4	158	2	28360906
Pubmed	Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas.	AQP1 AQP5	1.22e-04	4	158	2	12801959
Pubmed	Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.	ABCC3 ABCC1	1.22e-04	4	158	2	16946557
Pubmed	Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration.	AQP1 AQP5	1.22e-04	4	158	2	11382807
Pubmed	Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5.	AQP1 AQP5	1.22e-04	4	158	2	10870513
Pubmed	Impaired hearing in mice lacking aquaporin-4 water channels.	AQP1 AQP5	1.22e-04	4	158	2	11406631
Pubmed	Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress.	ABCC3 ABCC1	1.22e-04	4	158	2	18038766
Pubmed	Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects.	GCKR G6PC2	1.22e-04	4	158	2	20628598
Pubmed	Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians.	GCKR G6PC2	1.22e-04	4	158	2	19651812
Pubmed	Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases.	PELI2 PELI1	1.22e-04	4	158	2	16884718
Pubmed	An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways.	RIPK1 NOD1	1.22e-04	4	158	2	10880512
Pubmed	Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.	PELI2 PELI1	1.22e-04	4	158	2	19081057
Pubmed	Role of aquaporin water channels in eye function.	AQP1 AQP5	1.22e-04	4	158	2	12565800
Pubmed	Identification of ARHGEF17, DENND2D, FGFR3, and RB1 mutations in melanoma by inhibition of nonsense-mediated mRNA decay.	ARHGEF17 FGFR3	1.22e-04	4	158	2	18677770
Pubmed	Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice.	AQP1 AQP5	1.22e-04	4	158	2	10795927
Pubmed	Upregulation of AQP3 and AQP5 induced by dexamethasone and ambroxol in A549 cells.	AQP1 AQP5	1.22e-04	4	158	2	18280225
GeneFamily	Adhesion G protein-coupled receptors, subfamily B	ADGRB1 ADGRB3	8.87e-05	3	99	2	912
GeneFamily	Pellino E3 ubiquitin protein ligases	PELI2 PELI1	8.87e-05	3	99	2	676
GeneFamily	Zinc fingers SWIM-type\|Mitogen-activated protein kinase kinase kinases	ZSWIM5 ZSWIM6	1.04e-03	9	99	2	90
GeneFamily	Annexins\|Endogenous ligands	ANXA8L1 ANXA8	2.23e-03	13	99	2	404
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC1	2.23e-03	13	99	2	807
GeneFamily	Aquaporins	AQP1 AQP5	2.59e-03	14	99	2	305
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL1 DAPK1 AQP5 GRAMD2A ANOS1 CELSR1 LRRC1 FHIP1A	2.50e-07	177	159	8	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 UBR4 BTG2 DISP2 G6PC2 PYCR2 SYT13 UNC80	5.03e-07	194	159	8	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 UBR4 BTG2 DISP2 G6PC2 PYCR2 SYT13 UNC80	5.03e-07	194	159	8	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ANXA8L1 ANXA8 AQP5 C2orf72 SUGCT PIK3C2G KEL	1.33e-06	153	159	7	a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANXA8L1 ANXA8 AQP5 TGM1 ANOS1 SUGCT KEL	1.58e-06	157	159	7	dd08dc19d434e94a194076c462ee273c682abf55
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	ANXA8L1 ANXA8 AQP5 TGM1 ANOS1 SUGCT KEL	1.58e-06	157	159	7	70fd6c46db4250c7de5c4686a9500689402737f6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ACP6 PELI2 ATG2A LRIG2 SLC7A1 LIPE TTC21B	3.24e-06	175	159	7	2812ac2ef41d245db544697fb6da1883361c96e8
ToppCell	Control-Epithelial_alveolar-AT_1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL1 DAPK1 AQP5 GRAMD2A ANOS1 CELSR1 LRRC1	3.62e-06	178	159	7	aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCell	AT1_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 ANXA8L1 ANXA8 TGM1 ANOS1 LRRC1 DIAPH3	3.90e-06	180	159	7	e1964002681f80d8d62406b6ee52a01e1829ccf2
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DAPK1 AQP5 GRAMD2A ANOS1 CELSR1 LRRC1 FHIP1A	4.05e-06	181	159	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 SFI1 CPS1 PKD1L2 PIK3C2G LRP2 UNC80	4.51e-06	184	159	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCC3 SLC16A12 ANOS1 CELSR1 LRRC1 DIAPH3 FHIP1A	4.51e-06	184	159	7	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 SFI1 CPS1 PKD1L2 PIK3C2G LRP2 UNC80	4.51e-06	184	159	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 SFI1 CPS1 PKD1L2 PIK3C2G LRP2 UNC80	4.51e-06	184	159	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Control-Epithelial_alveolar\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL1 DAPK1 AQP5 GRAMD2A ANOS1 CELSR1 FHIP1A	4.67e-06	185	159	7	3937e026add96a396122139daf8011cfbc60e75c
ToppCell	LAM-Lymphoid-B-cell-2\|Lymphoid / Condition, Lineage and Cell class	PRSS16 CARMIL1 PELI1 BTG2 ABCB9 CD27 PYCR1	4.84e-06	186	159	7	bcfe0bf2f7f745146b74496a4fcfccd869ad7c6f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL1 DAPK1 AQP5 GRAMD2A ANOS1 CELSR1 FHIP1A	4.84e-06	186	159	7	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	B_cells-Plasma_cells_and_plasmablasts\|World / Immune cells in Kidney/Urine in Lupus Nephritis	XCR1 PRSS16 MEI1 STARD5 ABCB9 CD27 PYCR1	5.01e-06	187	159	7	9325cadd5f2c667d526696899e7aa36a98226d4b
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|Fibroblasts / Location, Cell class and cell subclass	PRSS16 ANXA8L1 ANXA8 AQP1 TGM1 LRP2 DIAPH3	5.57e-06	190	159	7	d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTG2 SV2A DISP2 G6PC2 PYCR2 SYT13 UNC80	5.76e-06	191	159	7	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF17 SLC16A12 FMN2 DISP2 G6PC2 SYT13 UNC80	5.76e-06	191	159	7	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 UBR4 DISP2 G6PC2 PYCR2 SYT13 UNC80	6.17e-06	193	159	7	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 UBR4 DISP2 G6PC2 PYCR2 SYT13 UNC80	6.17e-06	193	159	7	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL12A1 TROAP CIP2A PANX3 GRAMD2A FGFR3 DIAPH3	6.38e-06	194	159	7	c093c5e161b97ad770bfbaad3023eba4537101b5
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANXA8L1 DAPK1 CPS1 ANOS1 CELSR1 SYNE2 LRRC1	7.29e-06	198	159	7	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	mild-Plasmablast\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PRSS16 TROAP MEI1 ISOC2 ABCB9 CD27 PYCR1	7.29e-06	198	159	7	b14b9e67815f93fac7bd8e5e6f1aa100951b4ac1
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	CARMIL1 ANXA8L1 DAPK1 ANOS1 CELSR1 SYNE2 LRRC1	7.29e-06	198	159	7	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Epithelial_cells-AT1-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ABCC3 COL12A1 ANXA8L1 ANXA8 AQP5 ANOS1 DIAPH3	7.29e-06	198	159	7	fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ABCC3 ANXA8L1 ANXA8 AQP5 ANOS1 KEL FGFR3	7.53e-06	199	159	7	995d710d7302272e7951a5a5d766d1039089ee2b
ToppCell	E18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso\|E18.5-samps / Age Group, Lineage, Cell class and subclass	OOSP3 GPR17 ANXA8 AQP1 AQP5 GRAMD2A	1.22e-05	142	159	6	77fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR17 PKD1L1 ADAMTSL3 AQP5 ADGRF3	1.69e-05	89	159	5	b66575739cb5b89234bbb8a3ea2f244e0bd19cff
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR17 PKD1L1 ADAMTSL3 AQP5 ADGRF3	1.69e-05	89	159	5	26f01e8530b313dd5e95ea6c20fa362e34b9ed24
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR17 ADAMTSL3 AQP5 CD27 ADGRF3	1.79e-05	90	159	5	a0baaf2b3cf07d457f0d242fc213689cba6fd449
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GPR17 ADAMTSL3 AQP5 CD27 ADGRF3	1.79e-05	90	159	5	ab4b08c6ac8695b38f841c0ecf2bb2c032111d04
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 GCKR PKD1L2 PANX3 SLC11A1 CMKLR1	2.16e-05	157	159	6	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 GCKR PKD1L2 PANX3 SLC11A1 CMKLR1	2.16e-05	157	159	6	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 GCKR PKD1L2 PANX3 SLC11A1 CMKLR1	2.16e-05	157	159	6	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ANXA8L1 ANXA8 C2orf72 SUGCT SV2A KEL	2.66e-05	163	159	6	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 DAPK1 AQP1 SUGCT LRP2 DIAPH3	2.76e-05	164	159	6	382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell	mild_COVID-19_(asymptomatic)-Plasmablast\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TROAP ABCB9 CD27 CPT1C PYCR1 DIAPH3	2.95e-05	166	159	6	0cc3b9681bc000a1b00d3b60f79f16eea1c2e2e1
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 AQP1 TGM1 SUGCT LRP2 FGFR3	3.05e-05	167	159	6	ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ANXA8L1 ANXA8 TGM1 ANOS1 LRP2 DIAPH3	3.15e-05	168	159	6	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ANXA8L1 ANXA8 TGM1 ANOS1 LRP2 DIAPH3	3.15e-05	168	159	6	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WRNIP1 ARHGEF17 AQP5 GRAMD2A ABCB9 ARHGAP8	3.15e-05	168	159	6	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TROAP MYCT1 CIP2A ANOS1 DIAPH3 IL9R	3.48e-05	171	159	6	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	FLU-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	ZSWIM5 CIP2A KCTD17 ADGRF3 DIAPH3 IL9R	3.72e-05	173	159	6	26e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCell	BL-critical-LOC-Lymphoid-PC\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TROAP STARD5 ISOC2 ABCB9 PYCR1 DIAPH3	3.72e-05	173	159	6	90700a876d997f7c0f7b3899dffcda7fdafee547
ToppCell	FLU-Healthy-3\|FLU / Virus stimulation, Condition and Cluster	ZSWIM5 CIP2A KCTD17 ADGRF3 DIAPH3 IL9R	3.72e-05	173	159	6	32b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZSWIM5 ITGA7 ARHGEF17 SLC16A12 CDK5R1 C11orf96	3.84e-05	174	159	6	a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZSWIM5 ITGA7 ARHGEF17 SLC16A12 CDK5R1 C11orf96	3.84e-05	174	159	6	7cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCell	(03)_Secretory-(4)_1wkpi\|(03)_Secretory / shred by cell type and Timepoint	PELI1 AQP5 GRAMD2A BTG2 SYNE2 FGFR3	3.96e-05	175	159	6	06b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ADGRB3 LRP2 G6PC2 SYT13 UNC80	3.96e-05	175	159	6	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	facs-MAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PELI1 STAT4 CELSR1 ABCB9 CD27 KEL	4.09e-05	176	159	6	77c6103639acd0f3d6a2171c5f37a8083b6c2cf0
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	SMG1 SFI1 LYST NBAS TMEM168 ZDHHC23	4.22e-05	177	159	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Healthy-RBC\|Healthy / disease group, cell group and cell class	TROAP ADGRB3 AQP1 FBXO7 KEL DIAPH3	4.22e-05	177	159	6	945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAPK1 ANOS1 CELSR1 BTG2 FGFR3 FHIP1A	4.50e-05	179	159	6	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AQP5 GRAMD2A ANOS1 CELSR1 LRRC1 FHIP1A	4.50e-05	179	159	6	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 ANXA8 AQP5 GRAMD2A ANOS1 LRRC1	4.50e-05	179	159	6	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACP6 VWA7 ARHGEF17 STAT4 RGS9BP SYNE2	4.64e-05	180	159	6	e53e9f3ebd48fb8237515e740ba5d9880ed6ade3
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ACP6 VWA7 ARHGEF17 STAT4 RGS9BP SYNE2	4.64e-05	180	159	6	9d18aa1044945fe6481ea3284037a777657fd837
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PRSS16 CARMIL1 MEI1 ABCB9 CD27 PYCR1	4.78e-05	181	159	6	f7b08f662eb77ee7a777c6525ddc3195046aaf65
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADGRB3 ITGA7 ADAMTSL3 ARHGEF17 SLC16A12 C11orf96	4.78e-05	181	159	6	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACP6 TROAP ARHGEF17 SLC16A12 SV2A C11orf96	4.93e-05	182	159	6	c84f44391932080df31c8765e363c3dff64b2bd1
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	ANXA8L1 ANXA8 AQP5 CELSR1 FGFR3 FHIP1A	4.93e-05	182	159	6	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	ANXA8L1 ANXA8 AQP5 CELSR1 FGFR3 FHIP1A	4.93e-05	182	159	6	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	ANXA8L1 ANXA8 AQP5 CELSR1 FGFR3 FHIP1A	5.08e-05	183	159	6	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 ANXA8L1 ANXA8 AQP5 TGM1 ANOS1	5.24e-05	184	159	6	cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ADGRB3 ITGA7 ADAMTSL3 ARHGEF17 SLC16A12 STAT4	5.24e-05	184	159	6	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 ANXA8L1 ANXA8 AQP5 TGM1 ANOS1	5.24e-05	184	159	6	bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC3 AQP1 SLC16A12 SUGCT SYNE2 LRP2	5.24e-05	184	159	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	ILEUM-non-inflamed-(5)_IgG_plasma_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CARMIL1 MEI1 BTG2 ABCB9 CD27 PYCR1	5.40e-05	185	159	6	93b9a47357152ea95dfdfe8e7d111906a4adc551
ToppCell	Control-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	ABCC3 ABCC1 ANXA8 AQP5 ASAP1 ANOS1	5.40e-05	185	159	6	d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCT1 PELI2 PLXND1 KCTD17 EXOC3L4 C11orf96	5.40e-05	185	159	6	512a195ebbae445afe3722a3943020080daf2f3c
ToppCell	LV-07._Pericyte\|LV / Chamber and Cluster_Paper	ANXA8L1 ADGRB3 ADAMTSL3 ARHGEF17 SLC16A12 STAT4	5.40e-05	185	159	6	acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell	mild-Lymphocytic-Plasmablast\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	XCR1 MEI1 ISOC2 ABCB9 CD27 PYCR1	5.56e-05	186	159	6	060510c21b1e0889b7a6eeb15821b9e2f03a0f99
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 PELI1 STAT4 CELSR1 ABCB9 CD27	5.56e-05	186	159	6	e23e1246914e230369a716d0d666b98383bf8512
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESYT1 PELI1 STAT4 CELSR1 ABCB9 CD27	5.56e-05	186	159	6	4dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	COL12A1 ANOS1 CELSR1 LRRC1 DIAPH3 FHIP1A	5.56e-05	186	159	6	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	RV-07._Pericyte\|RV / Chamber and Cluster_Paper	ANXA8L1 ADGRB3 ADAMTSL3 ARHGEF17 SLC16A12 STAT4	5.56e-05	186	159	6	c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DAPK1 GRAMD2A ANOS1 CELSR1 SYNE2 FHIP1A	5.73e-05	187	159	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL12A1 GRAMD2A ANOS1 LRRC1 DIAPH3 FHIP1A	5.73e-05	187	159	6	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYCT1 ADGRB3 PLXND1 ASAP1 NOD1 CMKLR1	5.73e-05	187	159	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early\|lymph-node_spleen / Manually curated celltypes from each tissue	TROAP NOX5 ISOC2 PYCR1 KEL DIAPH3	5.73e-05	187	159	6	61d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL12A1 ANOS1 CELSR1 LRRC1 DIAPH3 FHIP1A	5.90e-05	188	159	6	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	AT1-AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 ANXA8L1 ANXA8 GRAMD2A ANOS1 LRRC1	5.90e-05	188	159	6	be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTG2 SV2A DISP2 G6PC2 SYT13 UNC80	5.90e-05	188	159	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	facs-Pancreas-Endocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTG2 DISP2 G6PC2 PYCR2 SYT13 UNC80	6.08e-05	189	159	6	010fdd70e9d0e21b856306a29ff877776a480319
ToppCell	ILEUM-inflamed-(5)_IgM_plasma_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PELI1 MEI1 BTG2 ABCB9 CD27 PYCR1	6.08e-05	189	159	6	fa9387d120cde6416998234c6ebd0ef74deed768
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PRSS16 TROAP CELSR1 PIK3C2G LRP2 FHIP1A	6.08e-05	189	159	6	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	ABCC3 ABCC1 ANXA8 ASAP1 ANOS1 FGFR3	6.26e-05	190	159	6	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ANXA8 LRRC43 TTLL6 CROCC2 LRP2	6.30e-05	117	159	5	26dec09112532f351fb7a2202bae84c365707b40
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)\|Striatum / BrainAtlas - Mouse McCarroll V32	ANXA8 LRRC43 TTLL6 CROCC2 LRP2	6.30e-05	117	159	5	db053c874e6739052dff1f91643e51b306236237
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL-Ependyma_Ccdc153.Ccdc153_(Ccdc153)--\|Striatum / BrainAtlas - Mouse McCarroll V32	ANXA8 LRRC43 TTLL6 CROCC2 LRP2	6.30e-05	117	159	5	80780223502d18f0d86a29ff3cb74aa8235103c7
ToppCell	Striatum-Macroglia-CSF_related-EPENDYMAL\|Striatum / BrainAtlas - Mouse McCarroll V32	ANXA8 LRRC43 TTLL6 CROCC2 LRP2	6.30e-05	117	159	5	40889f4a387846abbf54469cc4faf616bfe348d0
ToppCell	Striatum-Macroglia-CSF_related\|Striatum / BrainAtlas - Mouse McCarroll V32	ANXA8 LRRC43 TTLL6 CROCC2 LRP2	6.30e-05	117	159	5	e12e37e393257db85f7f5c13454095c44f59d374
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA7 ARHGEF17 SLC16A12 FBXL22 SV2A C11orf96	6.44e-05	191	159	6	5c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TROAP ISOC2 ABCB9 CD27 PYCR1 DIAPH3	6.44e-05	191	159	6	b23fdcd3090df9f58310b4dc8f7dc0c6d6b33226
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTG2 DISP2 G6PC2 PYCR2 SYT13 UNC80	6.44e-05	191	159	6	a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TLR9 VWA7 STAT4 CD27 BOLA2 IL9R	6.44e-05	191	159	6	d5086ffdba3635e649ad2ab9628634ddb1df7fdc
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 BTG2 DISP2 G6PC2 SYT13 UNC80	6.63e-05	192	159	6	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
Disease	autosomal recessive cutis laxa type IIB (implicated_via_orthology)	PYCR1 PYCR2	2.71e-05	2	154	2	DOID:0070137 (implicated_via_orthology)
Disease	glycine measurement, amino acid measurement	CPS1 PKD1L2	1.61e-04	4	154	2	EFO_0005134, EFO_0009767
Disease	gamma-glutamylcitrulline measurement	ABCC1 CPS1	1.61e-04	4	154	2	EFO_0800690
Disease	urinary sodium to creatinine ratio	GCKR CPS1	1.61e-04	4	154	2	EFO_0009883
Disease	Peripheral Nervous System Diseases	ABCC1 DAPK1 LYST CPT1C	1.84e-04	54	154	4	C4721453
Disease	Progeria	ZMPSTE24 PYCR1	2.68e-04	5	154	2	C0033300
Disease	Congenital muscular dystrophy (disorder)	ITGA7 SYNE2	4.00e-04	6	154	2	C0699743
Disease	stimulant use measurement	CPS1 ASAP1 NBAS	4.15e-04	28	154	3	EFO_0600076
Disease	Seckel syndrome (implicated_via_orthology)	WDR4 ATR	5.59e-04	7	154	2	DOID:0050569 (implicated_via_orthology)
Disease	level of Phosphatidylinositol (16:0_20:4) in blood serum	CCDC91 GCKR	7.42e-04	8	154	2	OBA_2045154
Disease	serine measurement	GCKR CPS1 DYNC1H1	8.07e-04	35	154	3	EFO_0009774
Disease	interleukin 4 measurement	CARMIL1 LRIG2 SUGCT	8.77e-04	36	154	3	EFO_0008184
Disease	2R,3R-dihydroxybutyrate measurement	CPS1 CROCC2	9.51e-04	9	154	2	EFO_0800314
Disease	glucagon-like peptide-1 measurement	COL12A1 ULK4	1.18e-03	10	154	2	EFO_0008465
Disease	Colorectal Carcinoma	ABCC3 ABCC1 FRMPD2 WRN TLR9 ADAMTSL3 LRP2 FLCN ATP11C FGFR3 SNRNP200	1.19e-03	702	154	11	C0009402
Disease	diffuse scleroderma (is_implicated_in)	WRN STAT4	1.44e-03	11	154	2	DOID:1580 (is_implicated_in)
Disease	level of Ceramide (d40:1) in blood serum	GCKR SYNE2	1.44e-03	11	154	2	OBA_2045185
Disease	epilepsy (implicated_via_orthology)	RIPK1 ITGA7 CDK5R1 SV2A DYNC1H1	1.69e-03	163	154	5	DOID:1826 (implicated_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	ZMPSTE24 SYNE2	1.73e-03	12	154	2	DOID:11726 (implicated_via_orthology)
Disease	glutaroyl carnitine measurement	ABCC1 CPS1	2.03e-03	13	154	2	EFO_0021005
Disease	triacylglycerol 52:3 measurement	GCKR FGFR3	2.72e-03	15	154	2	EFO_0010415
Disease	metabolite measurement	ABCC3 ABCC1 GCKR CPS1 PKD1L2 NBAS SUGCT SYNE2 G6PC2	2.80e-03	560	154	9	EFO_0004725
Disease	Abnormality of refraction	CCDC91 SMG1 FRMPD2 PKD1L1 GCKR ZSWIM6 ASAP1 NOD1 FBXO7 ULK4	2.90e-03	673	154	10	HP_0000539
Disease	idiopathic scoliosis (implicated_via_orthology)	KIF6 PPP2R3B	3.10e-03	16	154	2	DOID:0060250 (implicated_via_orthology)
Disease	glutarylcarnitine (C5-DC) measurement	ABCC1 CPS1	3.50e-03	17	154	2	EFO_0800030
Disease	gout	PRSS16 CARMIL1 GCKR LRP2 MED27	3.74e-03	196	154	5	EFO_0004274
Disease	phosphatidylcholine measurement	KIF6 GCKR MYO15B SUGCT SYNE2 DYNC1H1	3.86e-03	284	154	6	EFO_0010226
Disease	smoking behavior, BMI-adjusted waist circumference	CCDC91 AMZ1 ADAMTSL3 SV2A	3.89e-03	122	154	4	EFO_0004318, EFO_0007789
Disease	systemic lupus erythematosus (is_implicated_in)	TLR9 STAT4 SLC11A1	4.21e-03	62	154	3	DOID:9074 (is_implicated_in)
Disease	Chronic myeloproliferative disorder	WDR4 ATR	4.37e-03	19	154	2	C1292778
Disease	squamous cell carcinoma (is_marker_for)	RIPK1 TLR9	4.37e-03	19	154	2	DOID:1749 (is_marker_for)
Disease	Sarcomatoid Renal Cell Carcinoma	DAPK1 SYNE2 FMN2 FLCN	4.61e-03	128	154	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DAPK1 SYNE2 FMN2 FLCN	4.61e-03	128	154	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DAPK1 SYNE2 FMN2 FLCN	4.61e-03	128	154	4	C1266044
Disease	Papillary Renal Cell Carcinoma	DAPK1 SYNE2 FMN2 FLCN	4.61e-03	128	154	4	C1306837
Disease	Renal Cell Carcinoma	DAPK1 SYNE2 FMN2 FLCN	4.61e-03	128	154	4	C0007134
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	WRN PELI1 FAM193A ABCB9 TTC21B MED27 FHIP1A	5.04e-03	398	154	7	EFO_0003756, EFO_0003888, EFO_0004337

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLARVAALRRTCLFS	SUGCT	11	Q9HAC7
TATLTLTLRTCDRFS	SYT13	236	Q7L8C5
ITLAFSRTCGRSQLI	TTC21B	291	Q7Z4L5
SAELEATTLRICTRA	EXOC3L4	441	Q17RC7
LVRLGTQTFCSRVID	ESYT1	361	Q9BSJ8
LSLSEILSNIRSCRL	EPC2	511	Q52LR7
LISLCQRLSRSFLSR	DAPK1	311	P53355
SSCTDARLLALFTRT	ADGRF3	476	Q8IZF5
RVIVQASTSELLRCL	CDK5R1	141	Q15078
QRTLFCTLLIRTGFD	AMZ1	51	Q400G9
LVFVLCRASSLAARE	C2orf72	106	A6NCS6
QRSLCSSDFIRILVI	CD27	181	P26842
IRSERSVILINFCLS	ADGRB1	976	O14514
IRSERSIILINFCLS	ADGRB3	906	O60242
RILALANRITSCLTS	GPR17	301	Q13304
TLQLVLCVLATTDRR	AQP1	146	P29972
TTLNRCSCSFRVLVV	BOLA2	26	Q9H3K6
SATTRATLLTRSLNC	CELSR1	2726	Q9NYQ6
RLVTCLESLRVSLTS	DIAPH3	191	Q9NSV4
TFQTVETLTCLSLER	BBS10	516	Q8TAM1
RVAFSLRQTSCATAV	DISP2	1051	A7MBM2
FCLDSARQTRQRLSI	FAM193A	1236	P78312
ASAEFCNILSRVLSR	DAXX	101	Q9UER7
FQSRTLALSRCSLEV	ATG2A	801	Q2TAZ0
QLALCIFASTDSRRT	AQP5	141	P55064
AVSTCARLTAVLRDR	RGS9BP	51	Q6ZS82
ITCAELRRSSFLQNV	PPP2R3B	281	Q9Y5P8
SCLLSTTRSIERATI	PIK3C2G	1196	O75747
ATIRTQFDTCTVLTI	ABCC3	1466	O15438
LRTVLQSCLRESAIS	NOX5	146	Q96PH1
RSLLINAVEASCIRT	PYCR1	251	P32322
RLQSSFLLCTILTLS	OOSP3	6	A0A2R8YFM6
RSLFLFTDLIVCTTL	ARHGEF17	1306	Q96PE2
FITILCTRSATHLLR	ANXA8	201	P13928
VSLSLFRTLLNLSCE	FHIP1B	401	Q8N612
SRCLSLQITRISAFF	ANOS1	51	P23352
QLFSIVRQACVRSLS	FLCN	116	Q8NFG4
FAVRDRCSLASLLTI	PLXND1	1436	Q9Y4D7
CSSRSQVDRLVALAR	ISOC2	136	Q96AB3
SLALASVTIRSSRCR	NUDT9	16	Q9BW91
IFSQLDIRSLCRASL	FBXO48	46	Q5FWF7
CFSRLTVLRLSVNQI	NOD1	726	Q9Y239
ESISTCRFAQRVALI	KIF6	331	Q6ZMV9
SQASRTLRILTLEEC	LRRC14B	356	A6NHZ5
SRFARVLLTRSCAIL	SLC11A1	396	P49279
ERSFLDCTNRTVLVS	LRP2	2216	P98164
IQALRSSVSRVFDCL	MED27	21	Q6P2C8
SSNLFSLVQVSCLRI	OXA1L	321	Q15070
ISLRRLSFCRLNAVS	OR5J2	161	Q8NH18
RGCSSSVLRVSQLVL	H1-7	51	Q75WM6
VFLTTRQTLCREQKS	KCTD17	41	Q8N5Z5
IFTESLLCSSRLENI	NBAS	1121	A2RRP1
SLTVFCVRDNRLTRI	LRRC1	336	Q9BTT6
SFTRVQRVSCCFSLL	PKD1L2	1546	Q7Z442
LNRCAEFSQTLLSRR	MEI1	466	Q5TIA1
SAAILCFLRTALRQS	MEI1	1056	Q5TIA1
LRSTREVELVAFLSC	OASL	76	Q15646
CRLTSLSIFQIVSLS	PANX3	261	Q96QZ0
AASQRCLLEILRTFE	GCKR	286	Q14397
RVIRIESRLLSISCS	OXGR1	261	Q96P68
ILRDTFSESCIRISQ	MYO15B	1271	Q96JP2
SLLETLTVLRLSFCT	OR7C1	156	O76099
TRLFLEGRTETVRSC	CPT1C	591	Q8TCG5
TTFAANLLTLSCRIS	ATR	611	Q13535
CIIEVNARLSRSSAL	CPS1	711	P31327
DTLTSRINTPFRLCV	FHIP1A	371	Q05DH4
VKNICSTFSSRRILT	FASTKD5	56	Q7L8L6
CQRSVVIRTFITSDF	GMPS	631	P49915
FITILCTRSATHLLR	ANXA8L1	201	Q5VT79
SCLFDRDLREQLTTI	C2orf92	146	A0A1B0GVN3
QRISFELTQSICLRI	COL12A1	606	Q99715
RQRSLSSLELFLSCA	CCDC91	411	Q7Z6B0
VLLLFNSELRATICR	CROCC2	1081	H7BZ55
LLDVRSVLSLSAVCR	FBXO7	346	Q9Y3I1
IQRLSCSENELFVSR	FRMPD2	676	Q68DX3
DLTQSRRPLTSCTIF	DHPS	86	P49366
TAELAVSLLLTTCRR	GRHPR	111	Q9UBQ7
FTTRLHNCRNTVTLL	ASAP1	46	Q9ULH1
SFRLLCALTSLTILQ	G6PC2	291	Q9NQR9
SRTCSEELTLLLRIF	LYST	1351	Q99698
TLNLRDLFSTFTITR	MAN2B1	936	O00754
IQELRRAACSRTSIS	INO80D	421	Q53TQ3
DLCSRVTFVNFTVTR	DYNC1H1	3691	Q14204
LVLTSCRAFLVTARI	CARMIL1	46	Q5VZK9
LQLVRARFCTRVSDT	ITGA7	691	Q13683
SIFALCLRRDGTVLS	EML3	516	Q32P44
SACVLTTQAVTRLLR	DIP2A	1096	Q14689
FILVVAAVTLCRLRS	FGFR3	386	P22607
AFRISRLEQQLCSLS	GRAMD2A	331	Q8IUY3
EVLSFCLTVLSRRFE	ZMPSTE24	401	O75844
FCSEISLIVSPRRIS	FMN2	781	Q9NZ56
SRIQDALISSVCRLA	PKD1L1	1346	Q8TDX9
QTEALSQLFCSVRTL	CTU2	221	Q2VPK5
VRRLDTLLACFNLSS	FAM120B	691	Q96EK7
CNFGVVRTLTSDRLT	LRRC43	586	Q8N309
FLTLAALCRETRQAA	LIPE	1026	Q05469
QSTISRFACRIICER	PELI1	131	Q96FA3
FSVLLFVAVRLCRRS	PCDHB6	701	Q9Y5E3
RLSCTDTSVNRIFIL	OR1M1	186	Q8NGA1
LLLIQLVLSCFSDRS	ABCC1	181	P33527
AIFRVRAVTRCTSSL	NLE1	96	Q9NVX2
STQLLAQRLSRTCFR	SFI1	811	A8K8P3
LRFGTRSLCNSIISL	TMEM179B	121	Q7Z7N9
IRATATALERCSELQ	SYNE2	5576	Q8WXH0
LISFTCRFLLNSRVT	TMEM120A	146	Q9BXJ8
SQRFRSISTLELFTV	LRRC41	456	Q15345
TQFVCETVIRSLTLD	NBR1	646	Q14596
FLVTICTRAVTRCIS	SLC16A12	56	Q6ZSM3
CERRSNLSLASLTFQ	MYCT1	131	Q8N699
ITQSTISRFACRIVC	PELI2	131	Q9HAT8
SVIISALCTLTRRNL	SMG1	2766	Q96Q15
SLVNDFLLRVCDRLS	FBXL22	106	Q6P050
RSLLINAVEASCIRT	PYCR2	251	Q96C36
ASSSIREDIVRCLNL	WRN	706	Q14191
SRTFTCLTNNILRID	IL9R	51	Q01113
SFLSAVSTERCLSVL	MRGPRX1	111	Q96LB2
TTVRFVDSLICNSSR	NIF3L1	11	Q9GZT8
CSRIDLLSSLIYVSQ	RIPK1	656	Q13546
RRQCLLISLSVNSVF	SV2A	231	Q7L0J3
LRNCLFRSLVSQETS	ABCB9	261	Q9NP78
SSLLRTRGCVSEQRL	BTG2	21	P78543
VLRRLTSSVSCALDE	ANKHD1	171	Q8IWZ3
LTRLFTSNQILTSEC	CIP2A	41	Q8TCG1
SVFLLTIISSDRCIS	CMKLR1	126	Q99788
FLQSLECLRRSTQSL	C11orf96	396	Q7Z7L8
CRLFQTNTELLELTT	ATP11C	691	Q8NB49
FLQTLFRTQIIRSCE	XCR1	246	P46094
VNVAQSSLICSFLSR	TRIM77	421	I1YAP6
ATVLSDILRRCTVTA	ZSWIM5	1071	Q9P217
EICSVSFRLRSSLNR	ZNF223	291	Q9UK11
CQLLLEITTFLRETF	UNC80	1346	Q8N2C7
ILTSRFLRDTETCRQ	ZNF287	36	Q9HBT7
TRLRRLDVSCNSISF	TLR9	701	Q9NR96
TRLSRCLNTFDLVAL	SLC7A1	26	P30825
NVSTLSNRRFVLCGT	STAT4	366	Q14765
FEIIQSITDTLCVSR	STARD5	86	Q9NSY2
VAVRLFDQESCIRSL	TROAP	391	Q12815
SITRLFVVSCSLVVN	SLC35A4	276	Q96G79
IRSTNIFRNLESTRC	ACP6	161	Q9NPH0
FCSRLIIVLDSENST	TMEM168	536	Q9H0V1
LVINLSSCRYESVRR	TTLL6	61	Q8N841
ESSLRVTGCRQILRS	ARHGAP8	326	P85298
LTLDTICRDRSVFTA	ZDHHC23	321	Q8IYP9
ILTTCAADIQRQRFL	SNRNP200	1576	O75643
SFQVNAALLSRCRVI	WRNIP1	361	Q96S55
ATVLSDILRRCTLTT	ZSWIM6	1101	Q9HCJ5
LSCLVQIASVRRSLF	XPO7	281	Q9UIA9
TVLRCLGLATRTVTN	TGM1	386	P22735
LSVRTVARRCTALTF	WDR4	96	P57081
RQISSFCSIDCTTIL	UBR4	1096	Q5T4S7
SLTQERRCRVTFLVT	VWA7	431	Q9Y334
CLSFSRAETVAQLRS	PRSS16	346	Q9NQE7
RETGCITVLSRLFRT	TERB1	141	Q8NA31
SSCRELLSRVFLALV	UNC45A	661	Q9H3U1
LFVRRLCLQSIAFIS	TMEM33	226	P57088
ADSLRITAVSALCRI	ULK4	661	Q96C45
VREVKCRVLLTFTQT	ADAMTSL3	586	P82987
CVRSLRARIVQSFLQ	KEL	511	P23276
SLRQSRILTDVSICA	KLHL38	26	Q2WGJ6
CRSRVLSRLLFIAQT	LRIG2	16	O94898