Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC17A2 ABCC3 SLC11A2 ABCC5 GRID2 CLDN4 HCN2 SLC13A2 GRM7 SLC4A3 SLC1A5 SLC1A6 LETM1 RYR2 SLC4A1 SLC4A2 ABCB4 SLC9A1 KCNA2 CLCN2 SLC16A3 SLC15A1 ABCA6 SLC15A2 KCNH2 SLC22A13 SCN2A ATP2C2 HRH1 SLC17A7 ABCC12 ABCC2 ATP1A2	4.46e-16	1180	104	33	GO:0022857
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC17A2 ABCC3 SLC11A2 ABCC5 CLDN4 HCN2 SLC13A2 GRM7 SLC4A3 SLC1A6 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 KCNA2 CLCN2 SLC16A3 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 ABCC2 ATP1A2	1.14e-15	758	104	27	GO:0015318
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC17A2 ABCC3 SLC11A2 ABCC5 SLC13A2 SLC4A3 SLC1A5 SLC1A6 LETM1 SLC4A1 SLC4A2 ABCB4 SLC9A1 SLC16A3 SLC15A1 ABCA6 SLC15A2 ATP2C2 SLC17A7 ABCC12 ABCC2 ATP1A2	4.08e-15	477	104	22	GO:0022804
GeneOntologyMolecularFunction	transporter activity	SLC17A2 ABCC3 SLC11A2 ABCC5 GRID2 CLDN4 HCN2 SLC13A2 GRM7 SLC4A3 SLC1A5 SLC1A6 LETM1 RYR2 SLC4A1 SLC4A2 ABCB4 SLC9A1 KCNA2 CLCN2 SLC16A3 SLC15A1 ABCA6 SLC15A2 KCNH2 SLC22A13 SCN2A ATP2C2 HRH1 SLC17A7 ABCC12 ABCC2 ATP1A2	5.74e-15	1289	104	33	GO:0005215
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR1M1 CALCR HTR4 FFAR3 GPR42 OR10J6P MCHR2 GRM6 F2R GRM7 OR6K6 OR8B3 OR1N1 OR3A2 CELSR1 TAS2R8 ADRB1 CXCR4 OR10K1 ADGRE4P HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	4.76e-14	884	104	27	GO:0004930
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC17A2 SLC11A2 GRID2 CLDN4 HCN2 SLC13A2 GRM7 SLC4A3 SLC1A6 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 KCNA2 CLCN2 SLC16A3 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 ATP1A2	2.46e-13	793	104	25	GO:0015075
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR1M1 CALCR HTR4 FFAR3 HLA-DRA GPR42 OR10J6P MCHR2 GRID2 CLDN4 GRM6 F2R GRM7 OR6K6 OR8B3 OR1N1 OR3A2 CELSR1 TAS2R8 ADRB1 CXCR4 OR10K1 ADGRE4P HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	5.46e-12	1353	104	30	GO:0004888
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC17A2 SLC11A2 SLC13A2 SLC4A3 SLC1A6 LETM1 SLC4A1 SLC4A2 SLC9A1 SLC16A3 SLC15A1 SLC15A2 ATP2C2 SLC17A7 ATP1A2	4.76e-11	301	104	15	GO:0022853
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC17A2 SLC11A2 SLC13A2 SLC4A3 SLC1A5 SLC1A6 LETM1 SLC4A1 SLC4A2 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC17A7	4.38e-10	296	104	14	GO:0015291
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC17A2 SLC11A2 HCN2 SLC13A2 GRM7 SLC1A6 LETM1 RYR2 SLC9A1 KCNA2 SLC16A3 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 ATP1A2	5.26e-10	627	104	19	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC17A2 SLC11A2 HCN2 SLC13A2 GRM7 SLC1A6 LETM1 RYR2 SLC9A1 KCNA2 SLC16A3 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 ATP1A2	1.36e-09	664	104	19	GO:0008324
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC17A2 SLC11A2 HCN2 SLC13A2 GRM7 SLC1A6 LETM1 RYR2 SLC9A1 KCNA2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 ATP1A2	2.34e-09	465	104	16	GO:0046873
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC17A2 ABCC3 ABCC5 CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7 ABCC2	2.13e-08	171	104	10	GO:0015103
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 ABCC5 SLC13A2 SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC16A3 SLC22A13 SLC17A7 ABCC2	4.14e-08	293	104	12	GO:0008514
GeneOntologyMolecularFunction	symporter activity	SLC17A2 SLC11A2 SLC13A2 SLC1A5 SLC1A6 SLC16A3 SLC15A1 SLC15A2 SLC17A7	8.96e-08	150	104	9	GO:0015293
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC3 ABCC5 ABCB4 ABCA6 ATP2C2 ABCC12 ABCC2 ATP1A2	1.01e-07	109	104	8	GO:0042626
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC17A2 SLC11A2 SLC13A2 SLC1A6 SLC16A3 SLC15A1 SLC15A2 SLC17A7	2.01e-07	119	104	8	GO:0015294
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	2.01e-07	49	104	6	GO:0140359
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC17A2 HCN2 SLC13A2 SLC1A6 SLC9A1 SCN2A SLC17A7 ATP1A2	3.14e-06	171	104	8	GO:0015081
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC3 ABCC5 ABCB4 ABCA6 ATP2C2 ABCC12 ABCC2 ATP1A2	4.24e-06	178	104	8	GO:0015399
GeneOntologyMolecularFunction	antiporter activity	SLC4A3 SLC1A5 LETM1 SLC4A1 SLC4A2 SLC9A1 SLC17A7	7.86e-06	138	104	7	GO:0015297
GeneOntologyMolecularFunction	solute:proton symporter activity	SLC11A2 SLC16A3 SLC15A1 SLC15A2	8.07e-06	25	104	4	GO:0015295
GeneOntologyMolecularFunction	gated channel activity	GRID2 HCN2 GRM7 SLC1A5 RYR2 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7	9.73e-06	334	104	10	GO:0022836
GeneOntologyMolecularFunction	tripeptide transmembrane transporter activity	ABCC5 SLC15A1 SLC15A2	1.13e-05	9	104	3	GO:0042937
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	ABCC3 SLC13A2 SLC1A5 SLC1A6 SLC16A3 SLC22A13 SLC17A7 ABCC2	1.28e-05	207	104	8	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	ABCC3 SLC13A2 SLC1A5 SLC1A6 SLC16A3 SLC22A13 SLC17A7 ABCC2	1.33e-05	208	104	8	GO:0005342
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	CLDN4 SLC4A3 SLC1A6 SLC4A1 SLC4A2 CLCN2 SLC17A7	1.42e-05	151	104	7	GO:0008509
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC3 ABCC5 ABCC2	1.60e-05	10	104	3	GO:0043225
GeneOntologyMolecularFunction	dicarboxylic acid transmembrane transporter activity	SLC13A2 SLC1A5 SLC1A6 ABCC2	1.96e-05	31	104	4	GO:0005310
GeneOntologyMolecularFunction	chloride:bicarbonate antiporter activity	SLC4A3 SLC4A1 SLC4A2	3.78e-05	13	104	3	GO:0140900
GeneOntologyMolecularFunction	bicarbonate:monoatomic anion antiporter activity	SLC4A3 SLC4A1 SLC4A2	3.78e-05	13	104	3	GO:0140829
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7	4.91e-05	125	104	6	GO:0015108
GeneOntologyMolecularFunction	proton transmembrane transporter activity	SLC11A2 LETM1 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC17A7	5.77e-05	188	104	7	GO:0015078
GeneOntologyMolecularFunction	C4-dicarboxylate transmembrane transporter activity	SLC13A2 SLC1A5 SLC1A6	5.97e-05	15	104	3	GO:0015556
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC3 ABCC5 ABCC2	5.97e-05	15	104	3	GO:0008559
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	HTR4 ADRB1 HRH1 HRH4	6.06e-05	41	104	4	GO:0008227
GeneOntologyMolecularFunction	oligopeptide transmembrane transporter activity	ABCC5 SLC15A1 SLC15A2	7.32e-05	16	104	3	GO:0035673
GeneOntologyMolecularFunction	olfactory receptor activity	OR1M1 OR10J6P OR6K6 OR8B3 OR1N1 OR3A2 OR10K1 OR3A3 OR8B12 OR52B2	8.47e-05	431	104	10	GO:0004984
GeneOntologyMolecularFunction	channel activity	GRID2 CLDN4 HCN2 GRM7 SLC1A5 RYR2 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7	9.19e-05	525	104	11	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GRID2 CLDN4 HCN2 GRM7 SLC1A5 RYR2 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7	9.34e-05	526	104	11	GO:0022803
GeneOntologyMolecularFunction	monoatomic ion channel activity	GRID2 CLDN4 HCN2 GRM7 RYR2 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7	1.42e-04	459	104	10	GO:0005216
GeneOntologyMolecularFunction	acidic amino acid transmembrane transporter activity	SLC1A5 SLC1A6 SLC17A7	1.47e-04	20	104	3	GO:0015172
GeneOntologyMolecularFunction	peptide:proton symporter activity	SLC15A1 SLC15A2	1.60e-04	4	104	2	GO:0015333
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM6 GRM7	1.60e-04	4	104	2	GO:0001642
GeneOntologyMolecularFunction	neurotransmitter receptor activity	HTR4 GRID2 ADRB1 HRH1 HRH4	1.77e-04	100	104	5	GO:0030594
GeneOntologyMolecularFunction	G protein-coupled serotonin receptor activity	HTR4 HRH1 HRH4	1.97e-04	22	104	3	GO:0004993
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	HCN2 SLC9A1 KCNA2 KCNH2 SLC17A7 ATP1A2	2.41e-04	167	104	6	GO:0015079
GeneOntologyMolecularFunction	dipeptide transmembrane transporter activity	SLC15A1 SLC15A2	2.66e-04	5	104	2	GO:0071916
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	LETM1 SLC9A1 SLC17A7	3.67e-04	27	104	3	GO:0051139
GeneOntologyMolecularFunction	glutamate receptor activity	GRID2 GRM6 GRM7	3.67e-04	27	104	3	GO:0008066
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	HCN2 GRM7 KCNA2 CLCN2 KCNH2 SCN2A	3.83e-04	182	104	6	GO:0005244
GeneOntologyMolecularFunction	histamine receptor activity	HRH1 HRH4	3.98e-04	6	104	2	GO:0004969
GeneOntologyMolecularFunction	voltage-gated channel activity	HCN2 GRM7 KCNA2 CLCN2 KCNH2 SCN2A	4.06e-04	184	104	6	GO:0022832
GeneOntologyMolecularFunction	PDZ domain binding	IGSF5 GRID2 HCN2 GRM7 ADRB1	4.62e-04	123	104	5	GO:0030165
GeneOntologyMolecularFunction	3-chloroallyl aldehyde dehydrogenase activity	ALDH3B1 ALDH3A2	5.55e-04	7	104	2	GO:0004028
GeneOntologyMolecularFunction	ligand-gated channel activity	GRID2 HCN2 SLC1A5 RYR2 KCNH2 SLC17A7	5.82e-04	197	104	6	GO:0022834
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC4A3 SLC4A1 SLC4A2	6.10e-04	32	104	3	GO:0015106
GeneOntologyMolecularFunction	solute:inorganic anion antiporter activity	SLC4A3 SLC4A1 SLC4A2	6.10e-04	32	104	3	GO:0005452
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC3 ABCC5 ABCC2	7.30e-04	34	104	3	GO:0042910
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC3 ABCC2	7.37e-04	8	104	2	GO:0015431
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC17A2 SLC13A2 SLC1A6 SLC17A7	8.49e-04	81	104	4	GO:0015370
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM6 GRM7	9.44e-04	9	104	2	GO:0098988
GeneOntologyMolecularFunction	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	ALDH3B1 ALDH3A2	9.44e-04	9	104	2	GO:0043878
GeneOntologyMolecularFunction	urate transmembrane transporter activity	SLC17A2 SLC22A13	9.44e-04	9	104	2	GO:0015143
GeneOntologyMolecularFunction	peptide transmembrane transporter activity	SLC15A1 SLC15A2	9.44e-04	9	104	2	GO:1904680
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM6 GRM7	9.44e-04	9	104	2	GO:0001640
GeneOntologyMolecularFunction	salt transmembrane transporter activity	SLC17A2 SLC22A13	9.44e-04	9	104	2	GO:1901702
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	GRM7 LETM1 RYR2 ATP2C2 HRH1	1.17e-03	151	104	5	GO:0015085
GeneOntologyMolecularFunction	manganese ion transmembrane transporter activity	SLC11A2 ATP2C2	1.18e-03	10	104	2	GO:0005384
GeneOntologyMolecularFunction	L-aspartate transmembrane transporter activity	SLC1A5 SLC1A6	1.18e-03	10	104	2	GO:0015183
GeneOntologyMolecularFunction	amide transmembrane transporter activity	ABCC5 SLC15A1 SLC15A2	1.36e-03	42	104	3	GO:0042887
GeneOntologyMolecularFunction	scaffold protein binding	PSAP GRID2 RYR2 KCNH2	1.42e-03	93	104	4	GO:0097110
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	LETM1 SLC9A1 SLC17A7	1.46e-03	43	104	3	GO:0140828
GeneOntologyMolecularFunction	sodium:phosphate symporter activity	SLC17A2 SLC17A7	1.71e-03	12	104	2	GO:0005436
GeneOntologyMolecularFunction	G protein-coupled neurotransmitter receptor activity	ADRB1 HRH4	2.02e-03	13	104	2	GO:0099528
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 ABCC5 ABCB4 ABCA6 ATP2C2 ABCC12 ABCC2 ATP1A2	2.16e-03	441	104	8	GO:0016887
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9A1 SLC17A7	2.35e-03	14	104	2	GO:0015386
GeneOntologyMolecularFunction	sodium ion binding	SCN2A ATP1A2	2.35e-03	14	104	2	GO:0031402
GeneOntologyMolecularFunction	L-glutamate transmembrane transporter activity	SLC1A6 SLC17A7	2.70e-03	15	104	2	GO:0005313
GeneOntologyMolecularFunction	aldehyde dehydrogenase (NAD+) activity	ALDH3B1 ALDH3A2	2.70e-03	15	104	2	GO:0004029
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GRID2 HCN2 RYR2 KCNH2 SLC17A7	3.40e-03	193	104	5	GO:0015276
GeneOntologyMolecularFunction	aldehyde dehydrogenase [NAD(P)+] activity	ALDH3B1 ALDH3A2	3.47e-03	17	104	2	GO:0004030
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNA2 SCN2A	3.47e-03	17	104	2	GO:0099508
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	ABCC3 ABCC5 ABCC2	3.97e-03	61	104	3	GO:1901682
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9A1 SLC17A7	4.34e-03	19	104	2	GO:0022821
GeneOntologyMolecularFunction	odorant binding	OR6K6 OR8B3 OR10K1 OR8B12	4.40e-03	127	104	4	GO:0005549
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	CALCR MCHR2 F2R RXFP4	5.18e-03	133	104	4	GO:0008528
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC17A2 ABCC3 SLC11A2 ABCC5 GRID2 CLDN4 HCN2 SLC13A2 GRM6 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 ADRB1 KCNA2 CLCN2 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	1.18e-13	1115	104	29	GO:0034220
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC17A2 ABCC3 SLC11A2 ABCC5 GRID2 CLDN4 HCN2 SLC13A2 GRM6 F2R SLC4A3 SLC1A6 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 ADRB1 KCNA2 CLCN2 SLC15A1 SLC15A2 CXCR4 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	5.93e-13	1374	104	31	GO:0006811
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	SLC17A2 SLC11A2 ABCC5 CLDN4 HCN2 SLC13A2 GRM6 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 ADRB1 KCNA2 CLCN2 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	6.21e-13	1017	104	27	GO:0098660
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR1M1 PSAP CALCR HTR4 FFAR3 GPR42 OR10J6P MCHR2 ABHD6 GRM6 F2R GRM7 OR6K6 OR8B3 OR1N1 OR3A2 CELSR1 TAS2R8 ADRB1 CXCR4 OR10K1 ADGRE4P HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	2.97e-11	1395	104	29	GO:0007186
GeneOntologyBiologicalProcess	organic anion transport	SLC17A2 ABCC3 PSAP ABCC5 SLC13A2 GRM7 SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 ABCB4 SLC16A3 SLC22A13 SLC17A7 ABCC2 ATP1A2	8.12e-10	515	104	17	GO:0015711
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC17A2 SLC11A2 ABCC5 HCN2 SLC13A2 GRM6 F2R LETM1 RYR2 SLC9A1 ADRB1 KCNA2 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	9.33e-10	922	104	22	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC17A2 SLC11A2 ABCC5 HCN2 SLC13A2 GRM6 F2R LETM1 RYR2 SLC9A1 ADRB1 KCNA2 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	1.39e-09	942	104	22	GO:0098655
GeneOntologyBiologicalProcess	monoatomic cation transport	SLC17A2 SLC11A2 ABCC5 HCN2 SLC13A2 GRM6 F2R LETM1 RYR2 SLC9A1 ADRB1 KCNA2 SLC15A1 SLC15A2 CXCR4 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	1.18e-08	1157	104	23	GO:0006812
GeneOntologyBiologicalProcess	metal ion transport	SLC17A2 SLC11A2 ABCC5 HCN2 SLC13A2 GRM6 F2R LETM1 RYR2 SLC9A1 ADRB1 KCNA2 CXCR4 KCNH2 SCN2A ATP2C2 HRH1 SLC17A7 CCR7 ABCC2 ATP1A2	2.24e-08	1000	104	21	GO:0030001
GeneOntologyBiologicalProcess	import across plasma membrane	SLC11A2 HCN2 GRM6 SLC1A5 SLC1A6 SLC9A1 ADRB1 SLC15A1 SLC15A2 KCNH2 ATP1A2	2.34e-08	230	104	11	GO:0098739
GeneOntologyBiologicalProcess	circulatory system process	ABCC3 FFAR3 GPR42 ABCC5 F2R SLC4A3 SLC1A5 RYR2 SLC9A1 ADRB1 SLC15A2 CXCR4 KCNH2 SCN2A HRH1 ABCC2 ATP1A2 OCLN	2.52e-08	733	104	18	GO:0003013
GeneOntologyBiologicalProcess	monoatomic anion transport	SLC17A2 ABCC3 ABCC5 CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7 ABCC2	3.00e-08	183	104	10	GO:0006820
GeneOntologyBiologicalProcess	action potential	FFAR3 GPR42 HCN2 SLC4A3 RYR2 SLC9A1 KCNA2 KCNH2 SCN2A ATP1A2	7.27e-08	201	104	10	GO:0001508
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	ABCC3 ABCC5 CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7 ABCC2	8.09e-08	153	104	9	GO:0098656
GeneOntologyBiologicalProcess	carboxylic acid transport	ABCC3 PSAP ABCC5 SLC13A2 GRM7 SLC1A5 SLC1A6 ABCB4 SLC16A3 SLC22A13 SLC17A7 ABCC2 ATP1A2	1.49e-07	410	104	13	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	ABCC3 PSAP ABCC5 SLC13A2 GRM7 SLC1A5 SLC1A6 ABCB4 SLC16A3 SLC22A13 SLC17A7 ABCC2 ATP1A2	1.58e-07	412	104	13	GO:0015849
GeneOntologyBiologicalProcess	dicarboxylic acid transport	ABCC5 SLC13A2 GRM7 SLC1A5 SLC1A6 SLC17A7 ABCC2 ATP1A2	1.68e-07	120	104	8	GO:0006835
GeneOntologyBiologicalProcess	transport across blood-brain barrier	ABCC3 ABCC5 SLC4A3 SLC1A5 SLC15A2 ABCC2 ATP1A2	2.84e-07	87	104	7	GO:0150104
GeneOntologyBiologicalProcess	manganese ion transmembrane transport	SLC11A2 RYR2 ATP2C2 HRH1	2.93e-07	12	104	4	GO:0071421
GeneOntologyBiologicalProcess	vascular transport	ABCC3 ABCC5 SLC4A3 SLC1A5 SLC15A2 ABCC2 ATP1A2	3.07e-07	88	104	7	GO:0010232
GeneOntologyBiologicalProcess	export across plasma membrane	ABCC5 SLC9A1 KCNA2 SLC15A2 KCNH2 ABCC2 ATP1A2	3.86e-07	91	104	7	GO:0140115
GeneOntologyBiologicalProcess	manganese ion transport	SLC11A2 RYR2 ATP2C2 HRH1	5.87e-07	14	104	4	GO:0006828
GeneOntologyBiologicalProcess	regulation of membrane potential	FFAR3 GPR42 GRID2 HCN2 SLC4A3 SLC1A6 RYR2 SLC9A1 ADRB1 KCNA2 KCNH2 SCN2A SLC17A7 ATP1A2	8.31e-07	559	104	14	GO:0042391
GeneOntologyBiologicalProcess	vascular process in circulatory system	ABCC3 ABCC5 F2R SLC4A3 SLC1A5 ADRB1 SLC15A2 HRH1 ABCC2 ATP1A2 OCLN	1.33e-06	344	104	11	GO:0003018
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	PSAP CALCR HTR4 FFAR3 GPR42 GRM6 GRM7 ADRB1 ADGRE4P HRH4	1.86e-06	286	104	10	GO:0007188
GeneOntologyBiologicalProcess	xenobiotic transmembrane transport	ABCC3 ABCC5 ABCB4 ABCC2	2.23e-06	19	104	4	GO:0006855
GeneOntologyBiologicalProcess	heart contraction	FFAR3 GPR42 SLC4A3 RYR2 SLC9A1 ADRB1 CXCR4 KCNH2 SCN2A ATP1A2	2.69e-06	298	104	10	GO:0060047
GeneOntologyBiologicalProcess	heart process	FFAR3 GPR42 SLC4A3 RYR2 SLC9A1 ADRB1 CXCR4 KCNH2 SCN2A ATP1A2	3.71e-06	309	104	10	GO:0003015
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	PSAP FFAR3 GPR42 GRM6 GRM7 HRH4	4.82e-06	86	104	6	GO:0007193
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	HCN2 SLC4A3 RYR2 KCNH2 SCN2A ATP1A2	5.15e-06	87	104	6	GO:0086001
GeneOntologyBiologicalProcess	regulation of blood circulation	FFAR3 GPR42 F2R SLC4A3 RYR2 SLC9A1 ADRB1 KCNH2 HRH1 ATP1A2	5.95e-06	326	104	10	GO:1903522
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR1M1 OR10J6P GRM6 OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 CXCR4 OR10K1 OR3A3 OR8B12 OR52B2	7.34e-06	582	104	13	GO:0050906
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	RYR2 SLC9A1 ADRB1 KCNH2 SCN2A ATP1A2	7.59e-06	93	104	6	GO:0086003
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	SLC11A2 HCN2 GRM6 SLC9A1 ADRB1 KCNH2 ATP1A2	7.69e-06	142	104	7	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	SLC11A2 HCN2 GRM6 SLC9A1 ADRB1 KCNH2 ATP1A2	7.69e-06	142	104	7	GO:0098659
GeneOntologyBiologicalProcess	regulation of heart rate by chemical signal	FFAR3 GPR42 KCNH2	1.02e-05	9	104	3	GO:0003062
GeneOntologyBiologicalProcess	positive regulation of calcium ion transport	GRM6 F2R RYR2 SLC9A1 ADRB1 CXCR4 ATP2C2	1.31e-05	154	104	7	GO:0051928
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR1M1 OR10J6P OR6K6 RYR2 OR8B3 OR1N1 OR3A2 TAS2R8 OR10K1 OR3A3 OR8B12 OR52B2	1.32e-05	524	104	12	GO:0009593
GeneOntologyBiologicalProcess	tripeptide transmembrane transport	ABCC5 SLC15A1 SLC15A2	1.46e-05	10	104	3	GO:0035443
GeneOntologyBiologicalProcess	detection of stimulus	OR1M1 OR10J6P GRM6 OR6K6 RYR2 OR8B3 OR1N1 OR3A2 TAS2R8 CXCR4 OR10K1 OR3A3 OR8B12 OR52B2	1.58e-05	722	104	14	GO:0051606
GeneOntologyBiologicalProcess	xenobiotic transport	ABCC3 ABCC5 ABCB4 SLC15A2 ABCC2	1.78e-05	64	104	5	GO:0042908
GeneOntologyBiologicalProcess	carboxylic acid transmembrane transport	ABCC5 SLC13A2 SLC1A5 SLC1A6 SLC16A3 SLC17A7 ATP1A2	1.89e-05	163	104	7	GO:1905039
GeneOntologyBiologicalProcess	chloride transmembrane transport	CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7	2.21e-05	112	104	6	GO:1902476
GeneOntologyBiologicalProcess	transmission of nerve impulse	FFAR3 GPR42 GRM7 KCNA2 SCN2A ATP1A2	2.21e-05	112	104	6	GO:0019226
GeneOntologyBiologicalProcess	organic acid transmembrane transport	ABCC5 SLC13A2 SLC1A5 SLC1A6 SLC16A3 SLC17A7 ATP1A2	2.21e-05	167	104	7	GO:1903825
GeneOntologyBiologicalProcess	cardiac muscle contraction	RYR2 SLC9A1 ADRB1 CXCR4 KCNH2 SCN2A ATP1A2	2.21e-05	167	104	7	GO:0060048
GeneOntologyBiologicalProcess	regulation of the force of heart contraction	RYR2 SLC9A1 ADRB1 ATP1A2	2.23e-05	33	104	4	GO:0002026
GeneOntologyBiologicalProcess	blood circulation	FFAR3 GPR42 F2R SLC4A3 RYR2 SLC9A1 ADRB1 CXCR4 KCNH2 SCN2A HRH1 ATP1A2 OCLN	2.29e-05	648	104	13	GO:0008015
GeneOntologyBiologicalProcess	transition metal ion transport	SLC11A2 ABCC5 RYR2 ATP2C2 HRH1 ABCC2	2.32e-05	113	104	6	GO:0000041
GeneOntologyBiologicalProcess	sensory perception	OR1M1 PSAP OR10J6P GRM6 F2R GRM7 OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 KCNA2 CXCR4 OR10K1 OR3A3 OR8B12 OR52B2	2.47e-05	1072	104	17	GO:0007600
GeneOntologyBiologicalProcess	proton transmembrane transport	SLC11A2 LETM1 SLC9A1 SLC15A1 SLC15A2 SLC17A7 ATP1A2	2.48e-05	170	104	7	GO:1902600
GeneOntologyBiologicalProcess	positive regulation of calcium ion import	GRM6 ADRB1 CXCR4 ATP2C2	2.52e-05	34	104	4	GO:0090280
GeneOntologyBiologicalProcess	tripeptide import across plasma membrane	SLC15A1 SLC15A2	2.52e-05	2	104	2	GO:0140207
GeneOntologyBiologicalProcess	calcium ion transmembrane transport	GRM6 F2R LETM1 RYR2 SLC9A1 ADRB1 ATP2C2 HRH1 CCR7 ATP1A2	2.92e-05	392	104	10	GO:0070588
GeneOntologyBiologicalProcess	membrane depolarization during action potential	HCN2 KCNH2 SCN2A ATP1A2	3.17e-05	36	104	4	GO:0086010
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR1M1 OR10J6P OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 OR10K1 OR3A3 OR8B12 OR52B2	3.38e-05	485	104	11	GO:0050907
GeneOntologyBiologicalProcess	tripeptide transport	ABCC5 SLC15A1 SLC15A2	3.43e-05	13	104	3	GO:0042939
GeneOntologyBiologicalProcess	regulation of heart contraction	FFAR3 GPR42 SLC4A3 RYR2 SLC9A1 ADRB1 KCNH2 ATP1A2	3.83e-05	249	104	8	GO:0008016
GeneOntologyBiologicalProcess	behavior	SLC11A2 PSAP GATM INPP5F GRM6 GRM7 CELSR1 ADRB1 KCNA2 SCN2A HRH1 SLC17A7 RXFP4 ATP1A2 TMEM18	3.98e-05	891	104	15	GO:0007610
GeneOntologyBiologicalProcess	regulation of amine transport	FFAR3 GPR42 GRM7 KCNA2 SLC15A1 ATP1A2	4.10e-05	125	104	6	GO:0051952
GeneOntologyBiologicalProcess	actin-mediated cell contraction	RYR2 SLC9A1 ADRB1 KCNH2 SCN2A ATP1A2	4.49e-05	127	104	6	GO:0070252
GeneOntologyBiologicalProcess	chloride transport	CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7	4.69e-05	128	104	6	GO:0006821
GeneOntologyBiologicalProcess	chemical homeostasis	SLC11A2 FFAR3 GPR42 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 ABCB4 SLC9A1 ADRB1 KCNH2 ATP2C2 SLC17A7 CCR7 ABCC2 ATP1A2	4.89e-05	1249	104	18	GO:0048878
GeneOntologyBiologicalProcess	calcium ion transport	GRM6 F2R LETM1 RYR2 SLC9A1 ADRB1 CXCR4 ATP2C2 HRH1 CCR7 ATP1A2	5.23e-05	509	104	11	GO:0006816
GeneOntologyBiologicalProcess	regulation of action potential	FFAR3 GPR42 SLC4A3 RYR2 SLC9A1	5.59e-05	81	104	5	GO:0098900
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	CLDN4 SLC4A3 SLC4A1 SLC4A2 CLCN2 SLC17A7	6.05e-05	134	104	6	GO:0098661
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	GRM6 F2R RYR2 SLC9A1 ADRB1 CXCR4 KCNH2 ATP2C2	6.10e-05	266	104	8	GO:0043270
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	SLC11A2 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 KCNH2 ATP2C2 CCR7 ABCC2 ATP1A2	6.47e-05	717	104	13	GO:0050801
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR1M1 OR10J6P OR6K6 OR8B3 OR1N1 OR3A2 OR10K1 OR3A3 OR8B12 OR52B2	6.61e-05	432	104	10	GO:0050911
GeneOntologyBiologicalProcess	amine transport	FFAR3 GPR42 GRM7 KCNA2 SLC15A1 ATP1A2	6.85e-05	137	104	6	GO:0015837
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	SLC11A2 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 ATP2C2 CCR7 ABCC2 ATP1A2	7.01e-05	622	104	12	GO:0006873
GeneOntologyBiologicalProcess	regulation of calcium:sodium antiporter activity	SLC9A1 ATP1A2	7.53e-05	3	104	2	GO:1903279
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	7.53e-05	3	104	2	GO:0002879
GeneOntologyBiologicalProcess	oligopeptide transmembrane transport	ABCC5 SLC15A1 SLC15A2	8.04e-05	17	104	3	GO:0035672
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC17A2 HCN2 SLC13A2 SLC9A1 SCN2A SLC17A7 ATP1A2	8.91e-05	208	104	7	GO:0035725
GeneOntologyBiologicalProcess	positive regulation of action potential	FFAR3 GPR42 SLC9A1	9.62e-05	18	104	3	GO:0045760
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR1M1 OR10J6P OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 OR10K1 OR3A3 OR8B12 OR52B2	9.94e-05	547	104	11	GO:0007606
GeneOntologyBiologicalProcess	renal system process	PSAP CLDN4 F2R SLC4A1 ADRB1 SLC15A2	1.09e-04	149	104	6	GO:0003014
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	GRM6 F2R LETM1 RYR2 ADRB1 CCR7 ATP1A2	1.16e-04	217	104	7	GO:0097553
GeneOntologyBiologicalProcess	striated muscle contraction	RYR2 SLC9A1 ADRB1 CXCR4 KCNH2 SCN2A ATP1A2	1.16e-04	217	104	7	GO:0006941
GeneOntologyBiologicalProcess	sensory perception of smell	OR1M1 OR10J6P OR6K6 OR8B3 OR1N1 OR3A2 OR10K1 OR3A3 OR8B12 OR52B2	1.21e-04	465	104	10	GO:0007608
GeneOntologyBiologicalProcess	actin filament-based movement	RYR2 SLC9A1 ADRB1 KCNH2 SCN2A ATP1A2	1.26e-04	153	104	6	GO:0030048
GeneOntologyBiologicalProcess	calcium ion import	GRM6 ADRB1 CXCR4 ATP2C2 HRH1	1.39e-04	98	104	5	GO:0070509
GeneOntologyBiologicalProcess	regulation of acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	1.50e-04	4	104	2	GO:0002877
GeneOntologyBiologicalProcess	cardiac conduction	SLC4A3 RYR2 SLC9A1 KCNH2 ATP1A2	1.52e-04	100	104	5	GO:0061337
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	HCN2 LETM1 SLC9A1 KCNA2 KCNH2 SLC17A7 ATP1A2	1.75e-04	232	104	7	GO:0071805
GeneOntologyBiologicalProcess	oligopeptide transport	ABCC5 SLC15A1 SLC15A2	2.05e-04	23	104	3	GO:0006857
GeneOntologyBiologicalProcess	G protein-coupled serotonin receptor signaling pathway	HTR4 HRH1 HRH4	2.05e-04	23	104	3	GO:0098664
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	SLC11A2 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 KCNH2 ATP2C2 CCR7 ATP1A2	2.26e-04	705	104	12	GO:0055080
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport	GRM6 F2R RYR2 SLC9A1 ADRB1	2.28e-04	109	104	5	GO:1904427
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	SLC11A2 CALCR HTR4 ABHD6 GATM F2R SLC1A5 SLC4A1 SLC4A2 ADRB1 MTHFD1 CXCR4 CCR7 OCLN TMEM18	2.29e-04	1043	104	15	GO:0048871
GeneOntologyBiologicalProcess	regulation of calcium ion transport	GRM6 F2R RYR2 SLC9A1 ADRB1 CXCR4 ATP2C2 ATP1A2	2.32e-04	323	104	8	GO:0051924
GeneOntologyBiologicalProcess	positive regulation of the force of heart contraction	RYR2 SLC9A1	2.49e-04	5	104	2	GO:0098735
GeneOntologyBiologicalProcess	oligopeptide import across plasma membrane	SLC15A1 SLC15A2	2.49e-04	5	104	2	GO:0140205
GeneOntologyBiologicalProcess	dipeptide import across plasma membrane	SLC15A1 SLC15A2	2.49e-04	5	104	2	GO:0140206
GeneOntologyBiologicalProcess	acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	2.49e-04	5	104	2	GO:0002525
GeneOntologyBiologicalProcess	positive regulation of cation transmembrane transport	GRM6 F2R RYR2 SLC9A1 ADRB1 KCNH2	2.53e-04	174	104	6	GO:1904064
GeneOntologyBiologicalProcess	regulation of calcium ion import	GRM6 ADRB1 CXCR4 ATP2C2	2.55e-04	61	104	4	GO:0090279
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	SLC11A2 F2R SLC4A3 LETM1 RYR2 SLC4A1 SLC4A2 SLC9A1 ATP2C2 CCR7 ATP1A2	2.60e-04	611	104	11	GO:0030003
GeneOntologyBiologicalProcess	neuronal action potential	FFAR3 GPR42 KCNA2 SCN2A	2.89e-04	63	104	4	GO:0019228
GeneOntologyCellularComponent	apical plasma membrane	SLC17A2 SLC11A2 IGSF5 ABCC5 CLDN4 SLC13A2 SLC4A2 ABCB4 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC22A13 ABCC2 OCLN	1.63e-08	487	103	15	GO:0016324
GeneOntologyCellularComponent	apical part of cell	SLC17A2 SLC11A2 IGSF5 ABCC5 CLDN4 SLC13A2 SLC4A2 ABCB4 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC22A13 ABCC2 OCLN	2.08e-07	592	103	15	GO:0045177
GeneOntologyCellularComponent	basal part of cell	ABCC3 SLC11A2 ABCC5 CLDN4 SLC1A5 SLC4A1 SLC4A2 SLC9A1 CLCN2 SLC16A3 ATP2C2	2.64e-06	378	103	11	GO:0045178
GeneOntologyCellularComponent	basal plasma membrane	ABCC3 ABCC5 CLDN4 SLC1A5 SLC4A1 SLC4A2 SLC9A1 CLCN2 SLC16A3 ATP2C2	9.98e-06	354	103	10	GO:0009925
GeneOntologyCellularComponent	transmembrane transporter complex	ABHD6 GRID2 CLDN4 HCN2 RYR2 SLC9A1 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7 ATP1A2	1.03e-05	523	103	12	GO:1902495
GeneOntologyCellularComponent	transporter complex	ABHD6 GRID2 CLDN4 HCN2 RYR2 SLC9A1 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7 ATP1A2	1.69e-05	550	103	12	GO:1990351
GeneOntologyCellularComponent	monoatomic ion channel complex	ABHD6 GRID2 CLDN4 HCN2 RYR2 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7	1.76e-05	378	103	10	GO:0034702
GeneOntologyCellularComponent	cell surface	SLC11A2 HLA-DRA IGSF5 F2R GRM7 SLC4A3 ADAM28 SLC4A1 SLC9A1 CXCR4 KCNH2 ADGRE4P CCR7 ABCC2 ATP1A2 OCLN DCBLD2	2.88e-05	1111	103	17	GO:0009986
GeneOntologyCellularComponent	cell-cell junction	IGSF5 CLDN4 SLC4A1 ABCB4 SLC9A1 KCNA2 CXCR4 SCN2A ABCC2 ATP1A2 OCLN	1.60e-04	591	103	11	GO:0005911
GeneOntologyCellularComponent	basolateral plasma membrane	ABCC3 ABCC5 SLC4A1 SLC4A2 SLC9A1 CLCN2 SLC16A3 ATP2C2	1.86e-04	320	103	8	GO:0016323
GeneOntologyCellularComponent	membrane protein complex	EMC3 CALCR HLA-DRA ABHD6 GRID2 CLDN4 HCN2 SLC1A6 RYR2 SLC4A1 SLC9A1 KCNA2 CLCN2 KCNH2 SCN2A SLC17A7 ATP1A2 TIMM44	3.55e-04	1498	103	18	GO:0098796
GeneOntologyCellularComponent	intercalated disc	SLC4A1 SLC9A1 SCN2A ATP1A2	3.55e-04	68	103	4	GO:0014704
GeneOntologyCellularComponent	intercellular canaliculus	ABCB4 ABCC2	8.46e-04	9	103	2	GO:0046581
GeneOntologyCellularComponent	postsynaptic membrane	ABHD6 GRID2 GRM6 F2R GRM7 SLC1A6 KCNA2 SLC16A3	8.87e-04	405	103	8	GO:0045211
GeneOntologyCellularComponent	dendrite	HTR4 GRID2 INPP5F HCN2 GRM6 GRM7 IGF2BP1 KCNA2 CLCN2 HRH1 HRH4 ATP1A2	1.05e-03	858	103	12	GO:0030425
GeneOntologyCellularComponent	dendritic tree	HTR4 GRID2 INPP5F HCN2 GRM6 GRM7 IGF2BP1 KCNA2 CLCN2 HRH1 HRH4 ATP1A2	1.07e-03	860	103	12	GO:0097447
GeneOntologyCellularComponent	cell-cell contact zone	SLC4A1 SLC9A1 SCN2A ATP1A2	1.21e-03	94	103	4	GO:0044291
GeneOntologyCellularComponent	parallel fiber to Purkinje cell synapse	GRID2 SLC1A6 SLC16A3	1.24e-03	43	103	3	GO:0098688
GeneOntologyCellularComponent	excitatory synapse	GRID2 SLC1A6 SLC16A3 SLC17A7	1.94e-03	107	103	4	GO:0060076
GeneOntologyCellularComponent	synaptic membrane	ABHD6 GRID2 GRM6 F2R GRM7 SLC1A6 KCNA2 SLC16A3 SCN2A	2.36e-03	583	103	9	GO:0097060
GeneOntologyCellularComponent	chloride channel complex	CLDN4 CLCN2 SLC17A7	2.80e-03	57	103	3	GO:0034707
MousePheno	abnormal food intake	PSAP HTR4 ABHD6 GATM GRID2 HCN2 SLC4A2 SCN2A HRH1 SLC17A7 RXFP4 ALDH3A2 TMEM18	1.70e-06	481	76	13	MP:0005449
MousePheno	increased susceptibility to pharmacologically induced seizures	HTR4 HCN2 GRM7 SLC4A3 LETM1 RYR2 KCNA2	3.26e-06	117	76	7	MP:0002906
MousePheno	increased susceptibility to induction of seizure by inducing agent	HTR4 HCN2 GRM7 SLC4A3 LETM1 RYR2 KCNA2	3.45e-06	118	76	7	MP:0012349
MousePheno	abnormal eating behavior	PSAP HTR4 ABHD6 GATM GRID2 HCN2 SLC4A2 IGF2BP1 SCN2A HRH1 SLC17A7 RXFP4 ALDH3A2 TMEM18	3.92e-06	604	76	14	MP:0001431
MousePheno	abnormal action potential	GRID2 HCN2 RYR2 KCNA2 SLC16A3 SCN2A ATP1A2	7.63e-06	133	76	7	MP:0005402
MousePheno	abnormal nervous system electrophysiology	GRID2 HCN2 SLC1A6 RYR2 KCNA2 CLCN2 SLC16A3 SCN2A SLC17A7 ATP1A2	1.10e-05	329	76	10	MP:0002272
MousePheno	abnormal seizure response to pharmacological agent	HTR4 HCN2 GRM7 SLC4A3 LETM1 RYR2 KCNA2	1.47e-05	147	76	7	MP:0000950
MousePheno	abnormal digestive system physiology	PSAP FFAR3 GPR42 GATM F2R SLC4A2 ABCB4 SLC9A1 CLCN2 SLC15A1 CXCR4 CCR7 OCLN	1.83e-05	599	76	13	MP:0001663
MousePheno	abnormal consumption behavior	PSAP HTR4 ABHD6 GATM GRID2 HCN2 SLC4A2 IGF2BP1 SCN2A HRH1 SLC17A7 RXFP4 ALDH3A2 TMEM18	1.93e-05	695	76	14	MP:0002069
MousePheno	abnormal sympathetic neuron innervation pattern	FFAR3 GPR42	8.72e-05	3	76	2	MP:0009284
MousePheno	lethality at weaning	PSAP GRID2 HCN2 SLC9A1 SLC17A7	9.18e-05	84	76	5	MP:0008569
MousePheno	abnormal seizure response to inducing agent	HTR4 HCN2 GRM7 SLC4A3 LETM1 RYR2 KCNA2	1.08e-04	201	76	7	MP:0009357
MousePheno	seizures	PSAP HTR4 HCN2 GRM7 SLC4A3 LETM1 RYR2 SLC9A1 KCNA2	1.40e-04	360	76	9	MP:0002064
MousePheno	abnormal sympathetic neuron physiology	FFAR3 GPR42	1.74e-04	4	76	2	MP:0009253
MousePheno	abnormal tumor necrosis factor (ligand) superfamily member 11 level	F2R ABCB4	1.74e-04	4	76	2	MP:0021028
MousePheno	convulsive seizures	PSAP HCN2 GRM7 RYR2 SLC9A1 KCNA2	1.81e-04	153	76	6	MP:0000947
MousePheno	abnormal digestion	FFAR3 GPR42 SLC4A2 ABCB4 SLC15A1	2.63e-04	105	76	5	MP:0001664
MousePheno	abnormal parotid gland physiology	SLC9A1 CCR7	2.89e-04	5	76	2	MP:0013532
Domain	G_PROTEIN_RECEP_F1_2	OR1M1 HTR4 FFAR3 GPR42 MCHR2 F2R OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 ADRB1 CXCR4 OR10K1 HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	1.49e-10	691	103	21	PS50262
Domain	GPCR_Rhodpsn	OR1M1 HTR4 FFAR3 GPR42 MCHR2 F2R OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 ADRB1 CXCR4 OR10K1 HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	1.53e-10	692	103	21	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR1M1 HTR4 FFAR3 MCHR2 F2R OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 ADRB1 CXCR4 OR10K1 HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	5.95e-10	670	103	20	IPR017452
Domain	7tm_1	OR1M1 HTR4 FFAR3 GPR42 MCHR2 F2R OR6K6 OR8B3 OR1N1 OR3A2 ADRB1 CXCR4 OR10K1 HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	7.12e-10	677	103	20	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR1M1 HTR4 FFAR3 GPR42 MCHR2 F2R OR6K6 OR8B3 OR1N1 OR3A2 ADRB1 CXCR4 OR10K1 HRH1 OR3A3 HRH4 RXFP4 OR8B12 CCR7 OR52B2	8.73e-10	685	103	20	PS00237
Domain	Anion_exchange_CS	SLC4A3 SLC4A1 SLC4A2	1.63e-07	3	103	3	IPR018241
Domain	ABC_membrane	ABCC3 ABCC5 ABCB4 ABCC12 ABCC2	1.81e-07	24	103	5	PF00664
Domain	ABC_tran	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	2.47e-07	48	103	6	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	2.47e-07	48	103	6	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	2.80e-07	49	103	6	PS00211
Domain	ABC_transporter-like	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	3.17e-07	50	103	6	IPR003439
Domain	ABC_TM1F	ABCC3 ABCC5 ABCB4 ABCC12 ABCC2	4.11e-07	28	103	5	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCC5 ABCB4 ABCC12 ABCC2	4.11e-07	28	103	5	IPR011527
Domain	MFS_dom	SLC17A2 UNC93A SLC16A3 SLC15A1 SLC15A2 SLC22A13 SLC17A7 OCLN	7.63e-07	134	103	8	IPR020846
Domain	Anion_exchange	SLC4A3 SLC4A1 SLC4A2	1.62e-06	5	103	3	IPR001717
Domain	ABC_transporter_CS	ABCC3 ABCC5 ABCB4 ABCC12 ABCC2	3.35e-06	42	103	5	IPR017871
Domain	ANION_EXCHANGER_2	SLC4A3 SLC4A1 SLC4A2	5.61e-06	7	103	3	PS00220
Domain	ANION_EXCHANGER_1	SLC4A3 SLC4A1 SLC4A2	5.61e-06	7	103	3	PS00219
Domain	Band3_cytoplasmic_dom	SLC4A3 SLC4A1 SLC4A2	1.34e-05	9	103	3	IPR013769
Domain	Band_3_cyto	SLC4A3 SLC4A1 SLC4A2	1.34e-05	9	103	3	PF07565
Domain	-	SLC4A3 SLC4A1 SLC4A2	1.34e-05	9	103	3	3.40.1100.10
Domain	HCO3_cotransp	SLC4A3 SLC4A1 SLC4A2	1.90e-05	10	103	3	PF00955
Domain	HCO3_transpt_C	SLC4A3 SLC4A1 SLC4A2	1.90e-05	10	103	3	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A3 SLC4A1 SLC4A2	1.90e-05	10	103	3	IPR016152
Domain	HCO3_transpt_euk	SLC4A3 SLC4A1 SLC4A2	1.90e-05	10	103	3	IPR003020
Domain	Oligopep_transport	SLC15A1 SLC15A2	3.01e-05	2	103	2	IPR004768
Domain	PTR2_symporter_CS	SLC15A1 SLC15A2	9.00e-05	3	103	2	IPR018456
Domain	PTR2_1	SLC15A1 SLC15A2	9.00e-05	3	103	2	PS01022
Domain	AAA+_ATPase	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	1.46e-04	144	103	6	IPR003593
Domain	AAA	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	1.46e-04	144	103	6	SM00382
Domain	GPR40-rel_orph	FFAR3 GPR42	1.79e-04	4	103	2	IPR013312
Domain	Multidrug-R_assoc	ABCC3 ABCC2	1.79e-04	4	103	2	IPR005292
Domain	Aldehyde_DH_NAD(P)	ALDH3B1 ALDH3A2	1.79e-04	4	103	2	IPR012394
Domain	PTR2_2	SLC15A1 SLC15A2	1.79e-04	4	103	2	PS01023
Domain	POT_fam	SLC15A1 SLC15A2	2.98e-04	5	103	2	IPR000109
Domain	PTR2	SLC15A1 SLC15A2	2.98e-04	5	103	2	PF00854
Domain	Olfact_rcpt	OR1M1 OR6K6 OR8B3 OR1N1 OR3A2 OR10K1 OR3A3 OR8B12 OR52B2	3.24e-04	393	103	9	IPR000725
Domain	Ion_trans_dom	HCN2 RYR2 KCNA2 KCNH2 SCN2A	4.22e-04	114	103	5	IPR005821
Domain	Ion_trans	HCN2 RYR2 KCNA2 KCNH2 SCN2A	4.22e-04	114	103	5	PF00520
Domain	Na-dicarboxylate_symporter	SLC1A5 SLC1A6	6.21e-04	7	103	2	IPR001991
Domain	NA_DICARBOXYL_SYMP_1	SLC1A5 SLC1A6	6.21e-04	7	103	2	PS00713
Domain	NA_DICARBOXYL_SYMP_2	SLC1A5 SLC1A6	6.21e-04	7	103	2	PS00714
Domain	Na-dicarboxylate_symporter_CS	SLC1A5 SLC1A6	6.21e-04	7	103	2	IPR018107
Domain	SDF	SLC1A5 SLC1A6	6.21e-04	7	103	2	PF00375
Domain	-	SLC1A5 SLC1A6	6.21e-04	7	103	2	1.10.3860.10
Domain	GPCR_3_mtglu_rcpt	GRM6 GRM7	8.25e-04	8	103	2	IPR000162
Domain	MFS_1	SLC17A2 SLC16A3 SLC22A13 SLC17A7	8.67e-04	77	103	4	PF07690
Domain	MFS	SLC17A2 SLC16A3 SLC22A13 SLC17A7	8.67e-04	77	103	4	IPR011701
Domain	ANF_lig-bd_rcpt	GRID2 GRM6 GRM7	1.10e-03	37	103	3	IPR001828
Domain	ANF_receptor	GRID2 GRM6 GRM7	1.10e-03	37	103	3	PF01094
Domain	Peripla_BP_I	GRID2 GRM6 GRM7	1.29e-03	39	103	3	IPR028082
Domain	ADR_fam	HTR4 ADRB1	1.32e-03	10	103	2	IPR002233
Domain	NCD3G	GRM6 GRM7	2.26e-03	13	103	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM6 GRM7	2.26e-03	13	103	2	IPR011500
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN2 KCNH2	2.62e-03	14	103	2	IPR003938
Domain	GPCR_3_CS	GRM6 GRM7	2.62e-03	14	103	2	IPR017979
Domain	G_PROTEIN_RECEP_F2_2	CALCR CELSR1 ADGRE4P	2.65e-03	50	103	3	PS00650
Domain	7tm_2	CALCR CELSR1 ADGRE4P	2.65e-03	50	103	3	PF00002
Domain	MFS	SLC17A2 SLC16A3 SLC22A13 SLC17A7	3.01e-03	108	103	4	PS50850
Domain	Chemokine_rcpt	CXCR4 CCR7	3.44e-03	16	103	2	IPR000355
Domain	-	ATP2C2 ATP1A2	3.44e-03	16	103	2	1.20.1110.10
Domain	Ald_DH_CS_GLU	ALDH3B1 ALDH3A2	3.44e-03	16	103	2	IPR029510
Domain	ATPase_P-typ_TM_dom	ATP2C2 ATP1A2	3.44e-03	16	103	2	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP2C2 ATP1A2	3.88e-03	17	103	2	IPR006068
Domain	Cation_ATPase_C	ATP2C2 ATP1A2	3.88e-03	17	103	2	PF00689
Domain	Ald_DH_CS_CYS	ALDH3B1 ALDH3A2	3.88e-03	17	103	2	IPR016160
Domain	ALDEHYDE_DEHYDR_GLU	ALDH3B1 ALDH3A2	4.35e-03	18	103	2	PS00687
Domain	Cation_ATPase_N	ATP2C2 ATP1A2	4.35e-03	18	103	2	PF00690
Domain	Cation_ATPase_N	ATP2C2 ATP1A2	4.35e-03	18	103	2	SM00831
Domain	ALDEHYDE_DEHYDR_CYS	ALDH3B1 ALDH3A2	4.35e-03	18	103	2	PS00070
Domain	GPCR_2_secretin-like	CALCR CELSR1 ADGRE4P	4.44e-03	60	103	3	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	CALCR CELSR1 ADGRE4P	4.65e-03	61	103	3	PS50261
Domain	Ald_DH_C	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	IPR016163
Domain	Ald_DH_N	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	IPR016161
Domain	-	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	3.40.605.10
Domain	Aldedh	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	PF00171
Domain	ATPase_P-typ_cation-transptr_N	ATP2C2 ATP1A2	4.84e-03	19	103	2	IPR004014
Domain	Aldehyde_DH_dom	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	IPR015590
Domain	-	ALDH3B1 ALDH3A2	4.84e-03	19	103	2	3.40.309.10
Pathway	WP_GPCRS_NONODORANT	CALCR HTR4 FFAR3 GPR42 GRM6 F2R GRM7 CELSR1 ADRB1 CXCR4 ADGRE4P HRH1 HRH4 RXFP4 CCR7	1.19e-10	266	90	15	MM15843
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 SLC11A2 ABCC5 SLC13A2 SLC4A3 SLC1A5 SLC1A6 LETM1 RYR2 SLC4A1 SLC4A2 ABCB4 SLC9A1 CLCN2 SLC16A3 SLC15A1 ABCA6 SLC15A2 ATP2C2 SLC17A7 ABCC2 ATP1A2	8.31e-10	736	90	22	M27287
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 SLC11A2 ABCC5 SLC13A2 SLC4A3 SLC1A5 SLC1A6 RYR2 SLC4A1 SLC4A2 ABCB4 SLC9A1 CLCN2 SLC16A3 SLC15A1 ABCA6 SLC15A2 ATP2C2 SLC17A7 ABCC2 ATP1A2	1.25e-09	681	90	21	MM14985
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC9A1 SLC15A1 SLC15A2 SLC17A7	2.73e-08	108	90	9	M823
Pathway	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC9A1 SLC15A1 SLC15A2 SLC17A7	2.96e-08	109	90	9	MM15074
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC11A2 SLC13A2 SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC17A7	3.48e-08	238	90	12	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC11A2 SLC13A2 SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC17A7	5.73e-08	249	90	12	M5988
Pathway	REACTOME_GPCR_LIGAND_BINDING	PSAP CALCR HTR4 FFAR3 MCHR2 GRM6 F2R GRM7 TAS2R8 ADRB1 CXCR4 HRH1 HRH4 RXFP4 CCR7	2.13e-07	463	90	15	M507
Pathway	KEGG_ABC_TRANSPORTERS	ABCC3 ABCC5 ABCB4 ABCA6 ABCC12 ABCC2	3.32e-07	44	90	6	M11911
Pathway	REACTOME_GPCR_LIGAND_BINDING	PSAP CALCR HTR4 FFAR3 GPR42 GRM6 F2R GRM7 ADRB1 CXCR4 HRH1 HRH4 RXFP4 CCR7	5.33e-07	430	90	14	MM15160
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	HTR4 FFAR3 GPR42 F2R OR3A2 ADRB1 CXCR4 HRH1 OR3A3 CCR7	6.00e-06	260	90	10	M39397
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	PSAP HTR4 FFAR3 MCHR2 F2R ADRB1 CXCR4 HRH1 HRH4 RXFP4 CCR7	7.83e-06	330	90	11	M18334
Pathway	REACTOME_SIGNALING_BY_GPCR	PSAP CALCR HTR4 FFAR3 MCHR2 ABHD6 GRM6 F2R GRM7 TAS2R8 ADRB1 CXCR4 HRH1 HRH4 RXFP4 CCR7	8.21e-06	702	90	16	M746
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	PSAP HTR4 FFAR3 GPR42 F2R ADRB1 CXCR4 HRH1 HRH4 RXFP4 CCR7	8.53e-06	333	90	11	MM14963
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	CALCR HTR4 MCHR2 GRID2 GRM6 F2R GRM7 ADRB1 HRH1 HRH4	8.92e-06	272	90	10	M13380
Pathway	REACTOME_SIGNALING_BY_GPCR	PSAP CALCR HTR4 FFAR3 GPR42 ABHD6 GRM6 F2R GRM7 ADRB1 CXCR4 HRH1 HRH4 RXFP4 CCR7	1.31e-05	646	90	15	MM14962
Pathway	WP_GPCRS_OTHER	MCHR2 F2R OR1N1 CELSR1 OR3A3 HRH4	2.79e-05	93	90	6	M39629
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A3 SLC4A1 SLC4A2	2.92e-05	10	90	3	M27335
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A3 SLC4A1 SLC4A2	2.92e-05	10	90	3	MM15073
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	HTR4 ADRB1 HRH1 HRH4	1.44e-04	42	90	4	M5868
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	HTR4 ADRB1 HRH1 HRH4	1.44e-04	42	90	4	MM14971
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	PSAP MCHR2 GRM6 GRM7 TAS2R8 CXCR4 HRH4 RXFP4 CCR7	1.75e-04	314	90	9	M600
Pathway	WP_CHOLESTASIS	ABCC3 ABCB4 ABCC2	2.26e-04	19	90	3	M45520
Pathway	WP_GPCRS_OTHER	OR1M1 CALCR CELSR1 ADRB1 CCR7	3.67e-04	96	90	5	MM15939
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCC3 ABCC5 ABCB4 ABCA6 ABCC2	4.23e-04	99	90	5	MM14986
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCC3 ABCC5 ABCB4 ABCA6 ABCC2	5.08e-04	103	90	5	M758
Pathway	BIOCARTA_MRP_PATHWAY	ABCC3 ABCB4	5.95e-04	6	90	2	M22078
Pathway	REACTOME_PARACETAMOL_ADME	ABCC3 ABCC5 ABCC2	8.15e-04	29	90	3	M45015
Pathway	WP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT	ABCC3 ABCB4 ABCC2	8.15e-04	29	90	3	M45551
Pathway	KEGG_HISTIDINE_METABOLISM	METTL6 ALDH3B1 ALDH3A2	8.15e-04	29	90	3	M12524
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCC3 ABCB4 ABCC2	9.02e-04	30	90	3	MM15866
Pathway	WP_MONOAMINE_GPCRS	HTR4 ADRB1 HRH1	9.94e-04	31	90	3	MM15871
Pathway	WP_MONOAMINE_GPCRS	HTR4 ADRB1 HRH1	1.20e-03	33	90	3	M39585
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	HTR4 F2R ADRB1 CXCR4 HRH1 OR8B12	1.21e-03	186	90	6	MM15994
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCC3 ABCB4 ABCC2	1.30e-03	34	90	3	M16393
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR1M1 OR6K6 OR8B3 OR1N1 OR3A2 OR10K1 OR3A3 OR8B12 OR52B2	1.35e-03	417	90	9	M4072
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCC3 ABCB4 ABCC2	1.42e-03	35	90	3	M39488
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	PSAP MCHR2 F2R CXCR4 RXFP4 CCR7	1.62e-03	197	90	6	M12289
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	GRM6 GRM7 TAS2R8	1.95e-03	39	90	3	M793
Pathway	REACTOME_PARACETAMOL_ADME	ABCC3 ABCC5 ABCC2	1.95e-03	39	90	3	MM15695
Pathway	REACTOME_SENSORY_PERCEPTION	OR1M1 OR6K6 OR8B3 OR1N1 OR3A2 TAS2R8 SCN2A OR10K1 OR3A3 OR8B12 OR52B2	2.36e-03	636	90	11	M41834
Pathway	WP_METABOLIC_REPROGRAMMING_IN_COLON_CANCER	SLC1A5 SLC16A3 DLST	2.41e-03	42	90	3	M39740
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	PSAP GRM6 GRM7 CXCR4 HRH4 RXFP4 CCR7	2.48e-03	289	90	7	MM15057
Pathway	REACTOME_SPHINGOLIPID_CATABOLISM	ALDH3B1 ALDH3A2	2.55e-03	12	90	2	M48264
Pathway	REACTOME_SPHINGOLIPID_CATABOLISM	ALDH3B1 ALDH3A2	2.55e-03	12	90	2	MM17238
Pathway	WP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS	ABCC3 ABCC2	2.55e-03	12	90	2	M48096
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	ABCC3 ABCC5 SLC4A3 SLC1A5 SLC15A2 ABCC2 ATP1A2 OCLN	1.07e-09	105	104	8	30280653
Pubmed	Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.	ABCC3 ABCC5 ABCC12 ABCC2	5.23e-09	8	104	4	15802388
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	ABCC3 ABCC5 ABCB4 SLC15A1 ABCA6 SLC15A2 ABCC2 ALDH3B1 ALDH3A2	7.22e-09	193	104	9	19343046
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	CALCR SLC13A2 SLC1A6 RYR2 SLC4A1 SLC4A2 SLC15A1 SLC15A2	1.24e-08	143	104	8	20424473
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC3 SLC11A2 KIAA1549 ABCC5 SLC1A5 SLC4A2 SLC9A1 CLCN2 SLC16A3 SLC15A1 ABCC2 OCLN DCBLD2	1.65e-08	569	104	13	30639242
Pubmed	Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex.	SLC4A3 SLC4A1 SLC4A2	2.60e-08	3	104	3	11208611
Pubmed	Expression and function of bicarbonate/chloride exchangers in the preimplantation mouse embryo.	SLC4A3 SLC4A1 SLC4A2	2.60e-08	3	104	3	7592657
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	HTR4 GRM6 GRM7 SLC1A6 HRH1 SLC17A7 HRH4	7.00e-08	118	104	7	19156168
Pubmed	Identification of an apical Cl(-)/HCO3(-) exchanger in the small intestine.	SLC4A3 SLC4A1 SLC4A2	1.04e-07	4	104	3	11842009
Pubmed	The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.	ABCC3 SLC15A1 ABCC2	1.04e-07	4	104	3	28408210
Pubmed	Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.	ABCC3 ABCC5 ABCC2	1.04e-07	4	104	3	19956884
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	EMC3 FBL LDAF1 ABHD6 KIAA1549 ABCC5 GPR108 LYSMD3 SLC1A5 SLC4A2 IGF2BP1 SLC9A1 MTHFD1 OCLN ALDH3A2	1.61e-07	952	104	15	38569033
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC3 ABCC5 ABCA6 ABCC2	5.29e-07	22	104	4	8894702
Pubmed	Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.	ABCC3 ABCC5 ABCC2	9.01e-07	7	104	3	20922799
Pubmed	Dissociation of heterotrimeric g proteins in cells.	HTR4 F2R CXCR4 HRH1 HRH4 RXFP4 CCR7	1.19e-06	179	104	7	18577758
Pubmed	Chromosomal location of the murine anion exchanger genes encoding AE2 and AE3.	SLC4A3 SLC4A1 SLC4A2	1.44e-06	8	104	3	7894173
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	CALCR HTR4 ADRB1 CXCR4 HRH1 HRH4 CCR7	2.48e-06	200	104	7	18240029
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	HCN2 RYR2 KCNA2 CLCN2 KCNH2 ATP1A2	4.02e-06	139	104	6	16985003
Pubmed	Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts.	GRM7 SPATA13 KLHL26	4.21e-06	11	104	3	22419666
Pubmed	The human olfactory receptor gene family.	OR1M1 OR10J6P OR6K6 OR8B3 OR1N1 OR3A2 OR10K1 OR3A3 OR8B12 OR52B2	5.39e-06	541	104	10	14983052
Pubmed	Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.	FFAR3 GPR42	8.86e-06	2	104	2	25637492
Pubmed	Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems.	ADRB1 KCNH2	8.86e-06	2	104	2	16914520
Pubmed	Immunolocalization of AE2 anion exchanger in rat and mouse epididymis.	SLC4A1 SLC4A2	8.86e-06	2	104	2	10491632
Pubmed	Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.	FFAR3 GPR42	8.86e-06	2	104	2	30478340
Pubmed	Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells.	CXCR4 CCR7	8.86e-06	2	104	2	19136936
Pubmed	Importance of a small N-terminal region in mammalian peptide transporters for substrate affinity and function.	SLC15A1 SLC15A2	8.86e-06	2	104	2	11944083
Pubmed	Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.	FFAR3 GPR42	8.86e-06	2	104	2	35858247
Pubmed	Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.	FFAR3 GPR42	8.86e-06	2	104	2	22506074
Pubmed	Overexpressed CXCR4 and CCR7 on the surface of NK92 cell have improved migration and anti-tumor activity in human colon tumor model.	CXCR4 CCR7	8.86e-06	2	104	2	31815761
Pubmed	MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function.	ABCC5 ABCC12	8.86e-06	2	104	2	35121660
Pubmed	Peptide transporters and their roles in physiological processes and drug disposition.	SLC15A1 SLC15A2	8.86e-06	2	104	2	18668438
Pubmed	Cardiac hypertrophy in anion exchanger 1-null mutant mice with severe hemolytic anemia.	SLC4A1 SLC4A2	8.86e-06	2	104	2	17056673
Pubmed	Lack of interaction between the peptidomimetic substrates captopril and cephradine.	SLC15A1 SLC15A2	8.86e-06	2	104	2	19246733
Pubmed	The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.	FFAR3 GPR42	8.86e-06	2	104	2	24748202
Pubmed	The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.	FFAR3 GPR42	8.86e-06	2	104	2	36362376
Pubmed	Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer.	CXCR4 CCR7	8.86e-06	2	104	2	17032700
Pubmed	Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma.	ABCC3 ABCC2	8.86e-06	2	104	2	29464551
Pubmed	Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2.	SLC15A1 SLC15A2	8.86e-06	2	104	2	18367661
Pubmed	Tissue distribution and thyroid hormone regulation of Pept1 and Pept2 mRNA in rodents.	SLC15A1 SLC15A2	8.86e-06	2	104	2	16202478
Pubmed	Chloride channel ClC-2 modulates tight junction barrier function via intracellular trafficking of occludin.	CLCN2 OCLN	8.86e-06	2	104	2	21956164
Pubmed	Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells.	CXCR4 CCR7	8.86e-06	2	104	2	15753377
Pubmed	Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.	FFAR3 GPR42	8.86e-06	2	104	2	20399779
Pubmed	Gene expression analysis of histamine receptors in peripheral blood mononuclear cells from individuals with clinically-isolated syndrome and different stages of multiple sclerosis.	HRH1 HRH4	8.86e-06	2	104	2	25293806
Pubmed	Cloning and structural characterization of a human non-erythroid band 3-like protein.	SLC4A1 SLC4A2	8.86e-06	2	104	2	3015590
Pubmed	Histamine H1- and H4-receptor expression in human colon-derived cell lines.	HRH1 HRH4	8.86e-06	2	104	2	37300703
Pubmed	Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.	ABCC3 ABCC2	8.86e-06	2	104	2	21841039
Pubmed	Chemokine receptor CCR7 expression predicts poor outcome in uveal melanoma and relates to liver metastasis whereas expression of CXCR4 is not of clinical relevance.	CXCR4 CCR7	8.86e-06	2	104	2	24052640
Pubmed	Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.	FFAR3 GPR42	8.86e-06	2	104	2	23110765
Pubmed	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.	FFAR3 GPR42	8.86e-06	2	104	2	26522986
Pubmed	Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.	FFAR3 GPR42	8.86e-06	2	104	2	27664183
Pubmed	Protease-activated receptor 1 suppresses Helicobacter pylori gastritis via the inhibition of macrophage cytokine secretion and interferon regulatory factor 5.	IRF5 F2R	8.86e-06	2	104	2	24866378
Pubmed	CCR7 and CXCR4 expression predicts lymph node status including micrometastasis in gastric cancer.	CXCR4 CCR7	8.86e-06	2	104	2	19513547
Pubmed	Cloning and characterization of a murine band 3-related cDNA from kidney and from a lymphoid cell line.	SLC4A1 SLC4A2	8.86e-06	2	104	2	3182834
Pubmed	The chemokine receptors CXCR4 and CCR7 are associated with tumor size and pathologic indicators of tumor aggressiveness in papillary thyroid carcinoma.	CXCR4 CCR7	8.86e-06	2	104	2	18696160
Pubmed	Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing.	CXCR4 CCR7	8.86e-06	2	104	2	31921208
Pubmed	Clinical Significance of Chemokine Receptor CXCR4 and CCR7 mRNA Expression in Patients With Colorectal Cancer.	CXCR4 CCR7	8.86e-06	2	104	2	34475074
Pubmed	G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.	FFAR3 GPR42	8.86e-06	2	104	2	37019194
Pubmed	Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration.	CXCR4 HRH1	8.86e-06	2	104	2	36732336
Pubmed	Differential expression of chemokine receptors on uveal melanoma cells and their metastases.	CXCR4 CCR7	8.86e-06	2	104	2	18235009
Pubmed	Antipsychotic pharmacogenomics in first episode psychosis: a role for glutamate genes.	GRID2 GRM7	8.86e-06	2	104	2	26905411
Pubmed	Delineating the role of histamine-1- and -4-receptors in a mouse model of Th2-dependent antigen-specific skin inflammation.	HRH1 HRH4	8.86e-06	2	104	2	24503582
Pubmed	3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.	FFAR3 GPR42	8.86e-06	2	104	2	38040866
Pubmed	Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.	FFAR3 GPR42	8.86e-06	2	104	2	35408893
Pubmed	Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.	ABCC3 ABCC2	8.86e-06	2	104	2	12704183
Pubmed	FFAR3 modulates insulin secretion and global gene expression in mouse islets.	FFAR3 GPR42	8.86e-06	2	104	2	26091414
Pubmed	Re: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.	ABCC3 ABCC5	8.86e-06	2	104	2	10340910
Pubmed	Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.	ABCC3 ABCC2	8.86e-06	2	104	2	25788542
Pubmed	Histamine H1, H3 and H4 receptors are involved in pruritus.	HRH1 HRH4	8.86e-06	2	104	2	21689731
Pubmed	GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.	FFAR3 GPR42	8.86e-06	2	104	2	27550964
Pubmed	Comparison of human and monkey peptide transporters: PEPT1 and PEPT2.	SLC15A1 SLC15A2	8.86e-06	2	104	2	15981923
Pubmed	Molecular and cellular biology of the erythrocyte anion exchanger (AE1).	SLC4A1 SLC4A2	8.86e-06	2	104	2	8434259
Pubmed	Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization.	SLC4A3 SLC4A2	8.86e-06	2	104	2	11248201
Pubmed	Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.	FFAR3 GPR42	8.86e-06	2	104	2	32073900
Pubmed	Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.	ABCC3 ABCC2	8.86e-06	2	104	2	11745434
Pubmed	Histamine H1 and H4 receptor expression on the ocular surface of patients with chronic allergic conjunctival diseases.	HRH1 HRH4	8.86e-06	2	104	2	28391980
Pubmed	Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.	SLC15A1 SLC15A2	8.86e-06	2	104	2	18713951
Pubmed	Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.	FFAR3 GPR42	8.86e-06	2	104	2	19630535
Pubmed	Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.	ABCC3 ABCC2	8.86e-06	2	104	2	30959153
Pubmed	The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters.	SLC15A1 SLC15A2	8.86e-06	2	104	2	20067523
Pubmed	Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.	ABCC3 ABCC2	8.86e-06	2	104	2	19088030
Pubmed	Anion exchanger isoform 2 operates in parallel with Na(+)/H(+) exchanger isoform 1 during regulatory volume decrease of human cervical cancer cells.	SLC4A2 SLC9A1	8.86e-06	2	104	2	11852051
Pubmed	Expression of chemokine receptors in human gastric cancer.	CXCR4 CCR7	8.86e-06	2	104	2	15867478
Pubmed	The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating occludin expression.	IGF2BP1 OCLN	8.86e-06	2	104	2	32385106
Pubmed	Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.	FFAR3 GPR42	8.86e-06	2	104	2	14722361
Pubmed	Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma.	ABCC3 ABCC5	8.86e-06	2	104	2	15688370
Pubmed	CXCR4 is dispensable for T cell egress from chronically inflamed skin via the afferent lymph.	CXCR4 CCR7	8.86e-06	2	104	2	24752354
Pubmed	[Expression of chemokine receptor CXCR4 and CCR7 in laryngeal carcinoma].	CXCR4 CCR7	8.86e-06	2	104	2	16494043
Pubmed	Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.	FFAR3 GPR42	8.86e-06	2	104	2	26260360
Pubmed	cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger.	SLC4A3 SLC4A2	8.86e-06	2	104	2	2294114
Pubmed	Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.	ABCC3 ABCC5	8.86e-06	2	104	2	9827529
Pubmed	Acute regulation of mouse AE2 anion exchanger requires isoform-specific amino acid residues from most of the transmembrane domain.	SLC4A1 SLC4A2	8.86e-06	2	104	2	17690150
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	ABCC3 ABCC5 SLC1A5 ABCC2	1.83e-05	52	104	4	26590417
Pubmed	Claudin-4 localization in epithelial ovarian cancer.	CLDN4 SLC1A5 OCLN DCBLD2	2.13e-05	54	104	4	36237976
Pubmed	Altered chemokine receptor expression in papillary thyroid cancer.	CXCR4 CCR7	2.65e-05	3	104	2	19731977
Pubmed	The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV.	SLC4A3 SLC4A1	2.65e-05	3	104	2	11994299
Pubmed	The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.	ABCC3 ABCC2	2.65e-05	3	104	2	12628490
Pubmed	The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.	FFAR3 GPR42	2.65e-05	3	104	2	12496283
Pubmed	Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.	ABCC3 ABCC2	2.65e-05	3	104	2	18799096
Pubmed	The TRPM1 Channel Is Required for Development of the Rod ON Bipolar Cell-AII Amacrine Cell Pathway in the Retinal Circuit.	GRM6 SLC17A7	2.65e-05	3	104	2	28899920
Pubmed	Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.	ABCC3 ABCC2	2.65e-05	3	104	2	17273943
Interaction	NHERF4 interactions	TAS2R8 SLC15A1 SLC15A2 ABCC2	3.60e-06	22	98	4	int:NHERF4
Interaction	RHOA interactions	EMC3 SLC11A2 FBL NOL6 KIAA1549 ABCC5 TRRAP SLC1A5 LETM1 SLC4A2 SLC9A1 KCNA2 SLC16A3 CXCR4 DLST OCLN ALDH3A2 TIMM44	1.69e-05	1199	98	18	int:RHOA
Interaction	OR10K1 interactions	TRRAP OR10K1	2.34e-05	2	98	2	int:OR10K1
Interaction	RHOG interactions	EMC3 SLC11A2 GATM KIAA1549 ABCC5 SLC1A5 LETM1 SLC4A2 SLC9A1 SLC16A3 CXCR4 DLST OCLN ALDH3A2 TIMM44	3.23e-05	910	98	15	int:RHOG
Cytoband	19q13.1	FBL FFAR3 GPR42	2.72e-04	55	104	3	19q13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3p25	EMC3 LSM3 METTL6 HRH1	4.42e-04	155	104	4	chr3p25
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	ABCC3 EME1 SLC4A1 IGF2BP1 CCR7 TMUB2	7.51e-04	473	104	6	chr17q21
GeneFamily	Solute carriers	SLC17A2 SLC11A2 SLC13A2 SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC9A1 SLC16A3 SLC15A1 SLC15A2 SLC22A13 SLC17A7	2.56e-09	395	82	14	752
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC5 ABCC12 ABCC2	2.72e-07	13	82	4	807
GeneFamily	Histamine receptors	HRH1 HRH4	1.21e-04	4	82	2	187
GeneFamily	Olfactory receptors, family 3	OR3A2 OR3A3	3.01e-04	6	82	2	150
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM6 GRM7	5.59e-04	8	82	2	281
GeneFamily	Aldehyde dehydrogenases	ALDH3B1 ALDH3A2	3.30e-03	19	82	2	398
Coexpression	GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN	INPP5F CELSR1 ABCA6 CCR7 ALDH3A2	2.51e-06	56	101	5	M19492
ToppCell	3'_v3-Lung-Myeloid_Dendritic-DC2\|Lung / Manually curated celltypes from each tissue	HLA-DRA SLC4A3 ADAM28 ABCB4 SLC15A1 ABCA6 ATP1A2	3.22e-07	190	104	7	468525c05e38158a3b8a445882b2d63dfb1d2c63
ToppCell	droplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PSAP IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	2.88e-06	169	104	6	b059304543876f514d5c7214f1f0a2da00f10a67
ToppCell	droplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PSAP IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	2.88e-06	169	104	6	945f737984c4de70a4e9c214053b005358053dd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCB4 CLCN2 ABCA6 ABCC2 OCLN	4.41e-06	182	104	6	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCB4 CLCN2 ABCA6 ABCC2 OCLN	4.41e-06	182	104	6	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC17A2 ABCB4 CLCN2 ABCA6 ABCC2 OCLN	4.41e-06	182	104	6	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 ABCB4 CLCN2 ABCA6 ABCC2 OCLN	4.55e-06	183	104	6	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA SLC1A6 ADAM28 ABCB4 SLC15A2 CXCR4	5.15e-06	187	104	6	d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCell	facs-Trachea-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF5 CLDN4 ADAM28 CELSR1 SLC15A2 OCLN	5.47e-06	189	104	6	f8959cc2c14899c8dfeb1b5e51e187537df2f03e
ToppCell	COVID_vent-Lymphocytic-B_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	HLA-DRA ADAM28 ABCB4 CELSR1 SLC15A2 CXCR4	5.64e-06	190	104	6	40b5e9e8f8fd8d84cb5b43e67b49267082348e9f
ToppCell	COVID_vent-Lymphocytic-B_cell-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	HLA-DRA ADAM28 ABCB4 CELSR1 SLC15A2 CXCR4	5.64e-06	190	104	6	a37a32dc1b931562a6660074e19d5598efc65284
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA SLC1A6 ADAM28 ABCB4 CXCR4 CCR7	5.99e-06	192	104	6	446c61c0d6ba89c619efe87ee495951299953981
ToppCell	10x5'-Lung-Myeloid_Dendritic-DC2\|Lung / Manually curated celltypes from each tissue	HLA-DRA GATM SLC4A3 ADAM28 ABCA6 ATP1A2	6.17e-06	193	104	6	c97f9b13057f803df63c696c6175ef8e0aba6fa7
ToppCell	facs-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF5 CLDN4 ADAM28 CELSR1 SLC15A2 OCLN	6.35e-06	194	104	6	3701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCell	facs-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF5 CLDN4 ADAM28 CELSR1 SLC15A2 OCLN	6.35e-06	194	104	6	65f9bf126be26114c2c3f4c46d48318986212a92
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HLA-DRA GATM ADAM28 CELSR1 KCNH2 SCN2A	6.54e-06	195	104	6	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ABCC3 PSAP GATM ABCC5 ADAM28 HRH1	6.94e-06	197	104	6	075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell	Sepsis-URO-Lymphocyte-B-B_intermediate\|URO / Disease, condition lineage and cell class	HLA-DRA ADAM28 ABCB4 CELSR1 CXCR4 CCR7	7.14e-06	198	104	6	aea2defa941adc8eeee601885cd13817ba108e57
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HLA-DRA SLC1A6 ADAM28 ABCB4 CXCR4 CCR7	7.14e-06	198	104	6	79c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCell	Transverse-(2)_B_cell-(23)_Follicular_B_cell\|Transverse / shred on region, Cell_type, and subtype	CALCR HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	7.35e-06	199	104	6	9c49e114e17cdefc2651050fc3251e59ea251289
ToppCell	control-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HLA-DRA GATM IRF5 SLC4A3 SLC1A5 ADAM28	7.35e-06	199	104	6	31825ba336603fe940dea6022e18ec25af110f4c
ToppCell	Transverse-B_cell-Follicular_B_cell\|Transverse / Region, Cell class and subclass	CALCR HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	7.35e-06	199	104	6	1fa6e464fc929e721738e175389b85018c5e975f
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PSAP HLA-DRA GATM TM6SF1 ADAM28 SLC16A3	7.56e-06	200	104	6	a1503bcc774bed9563eda7cf90b8b5bf4405ad85
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PSAP HLA-DRA GATM TM6SF1 ADAM28 SLC16A3	7.56e-06	200	104	6	25247f8b6ba6cd899ba6bd47e28e090d697e4632
ToppCell	Control-Epithelial_alveolar-AT_1-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CLDN4 CELSR1 SLC15A2 ATP2C2 ALDH3B1	2.09e-05	142	104	5	94e277f038f4006d99ff50222b0f5cf89bc3d46d
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP IRF5 TM6SF1 HRH1 XKRX	2.55e-05	148	104	5	31a7c2b20970070b14d2b955020320a6f99db547
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAP GATM IRF5 TM6SF1 HRH1	2.89e-05	152	104	5	27718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN4 ADRB1 KCNA2 ADGRE4P HRH1	2.89e-05	152	104	5	b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A1 ADRB1 SLC15A2 ADGRE4P HRH4	3.28e-05	156	104	5	5caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCell	facs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A1 ADRB1 SLC15A2 ADGRE4P HRH4	3.28e-05	156	104	5	758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-DC2\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HLA-DRA IRF5 SLC4A3 ADAM28 KCNA2	3.28e-05	156	104	5	03f3c5ffb27758fe63797143fcc938f9e8a4e10d
ToppCell	facs-Marrow-B-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSAP CCDC81 IRF5 ABCA6 ADGRE4P	3.38e-05	157	104	5	0966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCell	facs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSAP CCDC81 IRF5 ABCA6 ADGRE4P	3.38e-05	157	104	5	6ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRF5 TM6SF1 SLC16A3 CXCR4 ADGRE4P	3.70e-05	160	104	5	6329b0f02f9509086e563c2ed762a8ec693883b5
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRM6 SLC22A13 SCN2A HRH4 CCR7	3.92e-05	162	104	5	15d5d31a75e26bcd41919a00300c68e9f00f0002
ToppCell	facs-Heart-RA-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM IRF5 SLC13A2 ADRB1 ADGRE4P	4.04e-05	163	104	5	da7ab9582e8070b07ca628a6394c86684d37d6ef
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	MCHR2 SLC1A6 RYR2 ABCA6 KCNH2	4.16e-05	164	104	5	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HLA-DRA ADAM28 ABCB4 CXCR4 SCN2A	4.28e-05	165	104	5	8003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA TM6SF1 SLC4A3 SLC1A5 CCR7	4.28e-05	165	104	5	60b500eb2c10cccf309b8fb28a9119da22d6889c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA SLC1A6 ADAM28 CXCR4 CCR7	4.28e-05	165	104	5	83095377aedf960c05baa523869bdbd2b0a05f2d
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	SLC17A2 SLC1A5 SLC1A6 MTHFD1 OCLN	4.28e-05	165	104	5	b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HLA-DRA SLC4A3 ADAM28 ABCA6 CCR7	4.41e-05	166	104	5	d373f1092e85eeb317a7406032b259f11e6adbe0
ToppCell	droplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 TM6SF1 CXCR4 ADGRE4P CCR7	4.41e-05	166	104	5	e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCell	PND01-03-samps-Myeloid\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PSAP IRF5 TM6SF1 ADGRE4P ALDH3B1	4.41e-05	166	104	5	99dc8a186ec12d3563e81fa4618a814740332c73
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DRA SLC4A3 ADAM28 ABCA6 CCR7	4.41e-05	166	104	5	f453a1d545d59003d98485ac31e85e6cf451817c
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADRB1 SLC16A3 CXCR4 ADGRE4P SPATA13	4.67e-05	168	104	5	d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells\|GI_small-bowel / Manually curated celltypes from each tissue	HLA-DRA ADAM28 ABCB4 CELSR1 CCR7	4.67e-05	168	104	5	8e025bb0541746e232b77ac0e31412ae71420c47
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B\|GI_small-bowel / Manually curated celltypes from each tissue	HLA-DRA ADAM28 ABCB4 CELSR1 CCR7	4.67e-05	168	104	5	5535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADRB1 SLC16A3 CXCR4 ADGRE4P SPATA13	4.67e-05	168	104	5	f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	4.80e-05	169	104	5	411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCell	droplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	4.80e-05	169	104	5	39b1acfd099abb9de18c29c05c7a67709ea76775
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN4 KCNA2 ATP2C2 ADGRE4P HRH1	4.94e-05	170	104	5	a121e10099faaeb60251eec162f38caf7c4238c2
ToppCell	URO-Lymphocyte-B-B_intermediate\|URO / Disease, Lineage and Cell Type	HLA-DRA ADAM28 ABCB4 CELSR1 CCR7	4.94e-05	170	104	5	e11d1510518cedabeece96d4adbb90999e6326fa
ToppCell	Severe-B_naive-11\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	5.08e-05	171	104	5	7c2699f19ca38414447a286f7658f507882d57c2
ToppCell	facs-Heart-RA-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM IRF5 TM6SF1 ADRB1 ADGRE4P	5.08e-05	171	104	5	15fedb078d93ac4b7fd2945870b50a718f665487
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	5.08e-05	171	104	5	00739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell	facs-Heart-RA-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM IRF5 TM6SF1 ADRB1 ADGRE4P	5.08e-05	171	104	5	467f53033f172905e653d85aaa6751a00e5d9e10
ToppCell	droplet-Lung-nan-21m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	5.22e-05	172	104	5	51bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	5.22e-05	172	104	5	5f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell	droplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 SLC16A3 CXCR4 ADGRE4P SPATA13	5.22e-05	172	104	5	be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM IRF5 TM6SF1 ADRB1 CXCR4	5.36e-05	173	104	5	054f64462b648ba6b4b28b48c716dc01b2ddd790
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM IRF5 TM6SF1 ADRB1 CXCR4	5.36e-05	173	104	5	9a8fec9a08bb61456a4ea43ae1316bd3e197a773
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HCN2 GRM7 SLC4A3 SLC4A1 ABCB4	5.66e-05	175	104	5	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HCN2 GRM7 SLC4A3 SLC4A1 ABCB4	5.66e-05	175	104	5	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	droplet-Heart-HEART-1m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 GATM IRF5 TM6SF1 ADRB1	5.66e-05	175	104	5	43b9cfd7c47d57244565c641e57f3256b5900804
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 GATM IRF5 TM6SF1 ADRB1	5.66e-05	175	104	5	a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN4 KCNA2 ATP2C2 ADGRE4P HRH1	5.66e-05	175	104	5	f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 GATM IRF5 TM6SF1 ADRB1	5.82e-05	176	104	5	1df640f88667e2dad30e65279d6d33bba75024c1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM28 TAS2R8 CXCR4 OR10K1 CCR7	5.82e-05	176	104	5	274458d80f9f3f080248cbf64e4784ef351e7254
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-B_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM28 TAS2R8 CXCR4 OR10K1 CCR7	5.82e-05	176	104	5	d0a3e176df1270968efa79c00dc941c5e1c4f7aa
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DRA GATM ADAM28 ABCB4 SLC15A2	6.14e-05	178	104	5	812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCell	390C-Lymphocytic-B_cell-\|390C / Donor, Lineage, Cell class and subclass (all cells)	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.14e-05	178	104	5	02cb514096435a4d8c84f0cc12ae627db319621d
ToppCell	390C-Lymphocytic-B_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.14e-05	178	104	5	9af29e341087ba4dd3ef246cdbae6469ea9de15f
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.14e-05	178	104	5	6f50e2ee66bd9dc12fd3c9ea70e6d50ff76b02e8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.14e-05	178	104	5	b132605f237e766a21042b9a65a564d64c4fec10
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DRA ADAM28 ABCB4 SLC15A2 CXCR4	6.14e-05	178	104	5	5d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.14e-05	178	104	5	99cd5e517855f1a2d6d75fb2d439751f884862c1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA SLC1A6 ADAM28 CXCR4 CCR7	6.30e-05	179	104	5	a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 ABHD6 KIAA1549 SLC13A2 IGF2BP1	6.30e-05	179	104	5	d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HCN2 GRM7 SLC16A3 CXCR4 CCR7	6.30e-05	179	104	5	dd3cf8fd10dc257d933a7f45860dc2e244c158b7
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-DRA GATM ADAM28 ABCB4 SCN2A	6.30e-05	179	104	5	fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCell	Leuk-UTI-Lymphocyte-B-B_naive\|Leuk-UTI / Disease, Lineage and Cell Type	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.64e-05	181	104	5	fb0b5a94796b99c64091f9890f7a09c39bbc3f73
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HTR4 GRM6 F2R ABCA6 ATP1A2	6.64e-05	181	104	5	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	normal_Lymph_Node-T/NK_cells-Exhausted_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	HLA-DRA F2R ADRB1 CXCR4 ATP1A2	6.64e-05	181	104	5	7e12030965881b023f0d3d27d934fa648e2cc523
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HTR4 GRM6 F2R ABCA6 ATP1A2	6.64e-05	181	104	5	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	10x5'-Liver-Lymphocytic_B-Memory_B_cells\|Liver / Manually curated celltypes from each tissue	HLA-DRA ADAM28 ABCB4 CELSR1 CCR7	6.64e-05	181	104	5	a9f4df288c34e3b2b6ed861ac6cda970c3ee08b1
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLA-DRA SLC1A6 ADAM28 ABCB4 CXCR4	6.64e-05	181	104	5	0c52dd82e6b3dce3d6bb5c13501bf8383f7121e4
ToppCell	Influenza_Severe-B_naive\|World / Disease group and Cell class	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.82e-05	182	104	5	e4885a5e6065c9c403cb2d305228691d6ae4ecb6
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IGSF5 ABCC5 CELSR1 SLC15A2 OCLN	6.82e-05	182	104	5	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	Int-URO-Lymphocyte-B-B_naive\|Int-URO / Disease, Lineage and Cell Type	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	6.82e-05	182	104	5	af7482c63e87a53cf686200a8f4d5b9749235dcd
ToppCell	remission-B_naive\|World / disease stage, cell group and cell class	HLA-DRA GRM6 ADAM28 ABCB4 SLC15A2	6.82e-05	182	104	5	cc1dfd2de35aee1a26f7efd78e108b60a3556ec5
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC3 GATM KIAA1549 SLC15A1 ABCC2	7.00e-05	183	104	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF5 CLDN4 SLC13A2 KCNA2 ATP2C2	7.00e-05	183	104	5	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HTR4 GRM6 F2R ABCA6 ATP1A2	7.00e-05	183	104	5	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF5 CLDN4 SLC13A2 KCNA2 ATP2C2	7.00e-05	183	104	5	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	F2R SLC4A2 METTL6 ALDH3A2 NME7	7.18e-05	184	104	5	2c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCell	E12.5-Epithelial-airway_epithelial_cell-club_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IGSF5 CLDN4 ADAM28 ADRB1 OCLN	7.18e-05	184	104	5	a69c3c57cd939b2888f548a0fbca3392ad310445
ToppCell	E12.5-Epithelial-airway_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IGSF5 CLDN4 ADAM28 ADRB1 OCLN	7.18e-05	184	104	5	3df78b17098b50e1a7f2c8791bf2d0806328330a
ToppCell	Bac-SEP-Lymphocyte-B-B_naive\|Bac-SEP / Disease, Lineage and Cell Type	HLA-DRA ADAM28 ABCB4 CXCR4 CCR7	7.37e-05	185	104	5	4d9e1eeb353c0b1f82f557856e99c8bf04aa2a7f
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH3BGR GATM SLC15A1 ATP2C2 NME7	7.37e-05	185	104	5	fd1911b57927c03470f9387962ca9581e5643fb3
Computational	Genes in the cancer module 71.	ABCC3 SLC13A2 SLC1A6 SLC16A3	4.19e-06	22	55	4	MODULE_71
Computational	Membranal receptors.	HTR4 HLA-DRA CLDN4 SLC13A2 SLC4A3 SLC1A6 SLC4A1 SLC16A3 SLC15A2 CXCR4 KCNH2	4.99e-05	517	55	11	MODULE_64
Computational	Genes in the cancer module 162.	SLC17A2 SLC15A1 SLC15A2	1.16e-04	19	55	3	MODULE_162
Computational	Genes in the cancer module 218.	SLC17A2 SLC16A3 SLC15A1	1.36e-04	20	55	3	MODULE_218
Computational	Genes in the cancer module 186.	ABCC3 SLC1A6 SLC16A3	1.36e-04	20	55	3	MODULE_186
Drug	sodium	SLC17A2 ABCC3 GATM GRID2 CLDN4 HCN2 SLC13A2 SLC4A3 SLC1A5 SLC1A6 RYR2 SLC4A1 SLC4A2 SLC9A1 KCNA2 CLCN2 SLC15A1 SLC15A2 KCNH2 SCN2A ATP2C2 SLC17A7 DLST ABCC2 ATP1A2	6.60e-13	944	104	25	CID000000923
Drug	hydride	SLC11A2 GATM SLC13A2 SLC1A5 SLC1A6 LETM1 SLC4A1 SLC4A2 DERA SLC9A1 CLCN2 SLC16A3 SLC15A1 SLC15A2 MTHFD1 ATP2C2 DLST ATP1A2 ALDH3B1 ALDH3A2	1.08e-09	835	104	20	CID000000783
Drug	CMFDA	ABCC3 ABCC5 SLC15A1 CXCR4 CCR7 ABCC2	2.66e-08	40	104	6	CID000122297
Drug	malonate	SLC13A2 GRM6 GRM7 SLC1A5 SLC1A6 ADAM28 KCNH2 SCN2A DLST ALDH3A2	4.22e-08	209	104	10	CID000000867
Drug	verapamil	ABCC3 ABCC5 RYR2 ABCB4 SLC9A1 ADRB1 KCNA2 ABCA6 KCNH2 ATP2C2 HRH1 ABCC12 ABCC2 ATP1A2	5.15e-08	490	104	14	CID000002520
Drug	Clemastine	ABCB4 KCNH2 HRH1	9.26e-08	3	104	3	ctd:D002974
Drug	potassium	INPP5F HCN2 GRM6 GRM7 SLC1A5 SLC1A6 RYR2 SLC4A1 SLC9A1 KCNA2 CLCN2 MTHFD1 KCNH2 SCN2A ATP2C2 HRH1 HRH4 DLST ATP1A2	1.35e-07	1008	104	19	CID000000813
Drug	cimetidine	ABCC3 ABCC5 ABCB4 SLC9A1 SLC16A3 SLC22A13 HRH1 HRH4 ABCC2	1.36e-07	179	104	9	CID000002756
Drug	chloride	SLC17A2 HTR4 GRID2 CLDN4 HCN2 SLC13A2 SLC4A3 SLC1A5 SLC1A6 SLC4A1 SLC4A2 SLC9A1 ADRB1 CLCN2 SLC15A1 SLC15A2 SCN2A SLC17A7 ATP1A2	1.86e-07	1029	104	19	CID000000312
Drug	bumetanide	SLC17A2 SLC13A2 SLC1A6 SLC4A2 SLC9A1 SLC15A1 SLC15A2 SCN2A ATP1A2	5.04e-07	209	104	9	CID000002471
Drug	Digocin	ABCC3 RYR2 ABCB4 KCNH2 ABCC2 ATP1A2	8.12e-07	70	104	6	CID000003062
Drug	valinomycin	GATM SLC4A1 SLC4A2 ABCB4 ATP1A2	9.18e-07	39	104	5	CID000005649
Drug	methylimidazole acetaldehyde	HRH1 HRH4 ALDH3B1 ALDH3A2	9.34e-07	17	104	4	CID000193545
Drug	probenecid	ABCC3 CALCR ABCC5 ABCB4 SLC16A3 SLC22A13 ABCC2	1.56e-06	123	104	7	CID000004911
Drug	LTC4 (leukotriene C4	ABCC3 MCHR2 ABCC5 ABCB4 HRH1 ABCC12 CCR7 ABCC2	1.76e-06	180	104	8	CID000003907
Drug	2-fluoronorepinephrine	ADRB1 HRH1 HRH4	1.83e-06	6	104	3	CID000172745
Drug	AC1NB6SN	ABCC3 ABCC5 ABCC2	1.83e-06	6	104	3	CID004488324
Drug	pseudococaine	HTR4 GRID2 GRM6 F2R GRM7 SLC1A6 ADRB1 CXCR4 KCNH2 ATP2C2 HRH1 SLC17A7 CCR7	2.02e-06	570	104	13	CID000002826
Drug	estradiol-17 beta-glucuronide	ABCC3 ABCB4 ABCC2 OCLN	2.82e-06	22	104	4	ctd:C025483
Drug	Hydroxyzine	ABCB4 KCNH2 HRH1	3.20e-06	7	104	3	ctd:D006919
Drug	forskolin from Coleus forskohlii	CALCR HTR4 FFAR3 MCHR2 HCN2 GRM6 F2R GRM7 RYR2 SLC4A2 ABCB4 SLC9A1 ADRB1 CLCN2 HRH1 HRH4 RXFP4	3.27e-06	1013	104	17	CID000003413
Drug	Pivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ABCC3 CALCR HTR4 CCDC81 TM6SF1 F2R SLC15A1 SLC17A7	3.58e-06	198	104	8	6014_UP
Drug	Proglumide [6620-60-6]; Up 200; 12uM; HL60; HT_HG-U133A	SLC17A2 MAGEA11 GATM GRID2 ABCB4 CELSR1 SLC15A2 SLC17A7	3.72e-06	199	104	8	2363_UP
Drug	nicotine glucuronide	ABCC3 ABCB4 ABCC2	5.10e-06	8	104	3	CID003035848
Drug	T beta-MC	ABCC3 ABCB4 ABCC2	5.10e-06	8	104	3	CID000168408
Drug	desloratadine	KCNH2 HRH1 ABCC2	7.62e-06	9	104	3	ctd:C121345
Drug	6-methylpurine-2'-deoxyriboside	ABCC3 SLC11A2 ABCC5 ABCB4 ABCC2	8.76e-06	61	104	5	CID000097184
Drug	Verapamil	ABCC3 SLC11A2 ABCB4 ADRB1 KCNH2 ABCC2	8.77e-06	105	104	6	ctd:D014700
Drug	Perhexiline	ABCC3 ABCB4 KCNH2 ABCC2	8.94e-06	29	104	4	ctd:D010480
Drug	Loratadine	ABCB4 KCNH2 HRH1 ABCC2	1.03e-05	30	104	4	ctd:D017336
Drug	AC1L9E0Q	ABCC3 ABCC5 ABCB4 ABCC2	1.03e-05	30	104	4	CID000443095
Drug	adefovir	ABCC3 CALCR ABCC5 ABCC12 ABCC2	1.11e-05	64	104	5	CID000060172
Drug	AC1L3C9O	ABCC3 SLC11A2 ABCC5 ABCB4 ABCC2 ALDH3A2	1.15e-05	110	104	6	CID000002521
Drug	morphine hydrochloride	ABCC3 GRM6 GRM7 SLC1A5 ABCB4 ADRB1 CXCR4 HRH1 SLC17A7 HRH4 CCR7	1.27e-05	481	104	11	CID000004253
Drug	fexofenadine	ABCC3 KCNH2 HRH1 ABCC2	1.34e-05	32	104	4	ctd:C093230
Drug	tetrahydridoborate(1-	SLC4A3 SLC4A1 SLC4A2	1.49e-05	11	104	3	CID000028123
Drug	physcione	ABCC3 ABCB4 ABCC2	1.49e-05	11	104	3	ctd:C008905
Drug	D-isomer	KCNH2 HRH1 HRH4	1.49e-05	11	104	3	CID000006834
Drug	trandolapril	ADRB1 SLC15A1 SLC15A2	1.49e-05	11	104	3	ctd:C052035
Drug	AC1L1TSE	ABCC3 ABCC5 ABCB4 SLC15A1 ABCC2	1.98e-05	72	104	5	CID000060719
Drug	5(6)-carboxy-2',7'-dichlorofluorescein	ABCC3 ABCC2	2.07e-05	2	104	2	ctd:C053897
Drug	N-[(1R)-2-[[(1S)-1-(2-besylethyl)-3-phenyl-propyl]amino]-1-[(3,5-dimethyl-3-isoxazolin-4-yl)methylsulfonylmethyl]-2-keto-ethyl]morpholine-4-carboxamide	PSAP SLC4A1	2.07e-05	2	104	2	CID011840925
Drug	emedastine	KCNH2 HRH1	2.07e-05	2	104	2	ctd:C043345
Drug	glycylsarcosine	SLC15A1 SLC15A2	2.07e-05	2	104	2	ctd:C004194
Drug	quinaprilat	SLC15A1 SLC15A2	2.07e-05	2	104	2	ctd:C054501
Drug	Astemizole	KCNH2 HRH1	2.07e-05	2	104	2	DB00637
Drug	moexipril	SLC15A1 SLC15A2	2.07e-05	2	104	2	ctd:C058302
Drug	diphenylpyraline	KCNH2 HRH1	2.07e-05	2	104	2	ctd:C009871
Drug	Betahistine	KCNH2 HRH1	2.07e-05	2	104	2	ctd:D001621
Drug	E3040 glucuronide	ABCC3 ABCC2	2.07e-05	2	104	2	CID000443294
Drug	niflumic acid	SLC1A6 SLC4A1 SLC9A1 CLCN2 KCNH2 SLC17A7	2.37e-05	125	104	6	CID000004488
Drug	benzbromarone	ABCC3 ABCC5 ABCB4 ABCC2	2.42e-05	37	104	4	CID000002333
Drug	harmol sulfate	ABCC3 ABCC5 ABCC2	2.56e-05	13	104	3	CID005488302
Drug	MS-551	CALCR KCNA2 KCNH2	2.56e-05	13	104	3	CID000004486
Drug	Psora-4	KCNA2 KCNH2 SCN2A	2.56e-05	13	104	3	CID006603977
Drug	dimethindene	ADRB1 HRH1 HRH4	2.56e-05	13	104	3	CID000021855
Drug	tetradotoxin	HTR4 GRID2 GRM6 GRM7 ADRB1 KCNA2 SCN2A HRH1 HRH4 ATP1A2	2.68e-05	428	104	10	CID000020382
Drug	3-isoreserpine	ABCC3 ABCC5 ABCB4 ADRB1 ABCA6 ABCC12 ABCC2	2.71e-05	190	104	7	CID000005052
Drug	DETC-MeSO	GRID2 GRM6 GRM7 ALDH3A2	2.99e-05	39	104	4	CID003035711
Drug	ketanserin	HTR4 F2R ADRB1 KCNH2 HRH1 HRH4	3.09e-05	131	104	6	CID000003822
Drug	Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	CALCR ADAM28 CXCR4 SCN2A SLC17A7 HRH4 DCBLD2	3.10e-05	194	104	7	3173_UP
Drug	Ethamsylate [2624-44-4]; Up 200; 15.2uM; PC3; HT_HG-U133A	ABCC3 HTR4 SLC4A1 SCN2A SLC17A7 HRH4 ABCC2	3.20e-05	195	104	7	4576_UP
Drug	NSC293370	ADAM28 HRH1 HRH4	3.25e-05	14	104	3	CID000002781
Drug	Fosinopril	SLC15A1 SLC15A2 ABCC2	3.25e-05	14	104	3	ctd:D017328
Drug	tetramethylrosamine	ABCC3 ABCC5 ABCC2	3.25e-05	14	104	3	CID000443313
Drug	Tolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	CALCR GRM7 CXCR4 HRH1 SLC17A7 HRH4 ATP1A2	3.30e-05	196	104	7	4167_UP
Drug	docetaxel	ABCC3 ABCC5 F2R ABCB4 ABCA6 ABCC2	3.37e-05	133	104	6	ctd:C067311
Drug	Finasteride [98319-26-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A	ABCC3 GRM7 ADAM28 ADRB1 HRH1 SLC17A7 ATP1A2	3.41e-05	197	104	7	4766_UP
Drug	AC1L9NAZ	SLC11A2 CALCR GRM6 ABCB4 HRH1 HRH4 DLST	3.53e-05	198	104	7	CID000449606
Drug	Furazolidone [67-45-8]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ABCC3 CALCR GRM7 SLC16A3 HRH1 ABCC2 ATP1A2	3.64e-05	199	104	7	4178_UP
Drug	Nifenazone [2139-47-1]; Up 200; 13uM; MCF7; HT_HG-U133A	SLC17A2 GRM6 F2R CLCN2 SLC16A3 SLC15A1 KCNH2	3.76e-05	200	104	7	6016_UP
Drug	C12E8	SLC1A5 SLC4A1 ATP2C2 DLST	4.02e-05	42	104	4	CID000123921
Drug	MX-68	ABCC3 ABCC5 ABCC2	4.05e-05	15	104	3	CID006918310
Drug	PTBD	ABCC3 MCHR2 ABCC2	4.05e-05	15	104	3	CID000197408
Drug	PAK-104P	ABCC3 ABCC5 ABCC2	4.05e-05	15	104	3	CID000131368
Drug	Sodium	SLC4A1 SLC9A1 KCNH2 SCN2A SLC17A7	4.18e-05	84	104	5	ctd:D012964
Drug	serotonin	HTR4 F2R SLC1A6 SLC9A1 ADRB1 CLCN2 KCNH2 HRH1 SLC17A7 HRH4 ATP1A2	4.64e-05	554	104	11	CID000005202
Drug	mianserin	HTR4 ADRB1 KCNH2 HRH1 HRH4	4.95e-05	87	104	5	CID000004184
Drug	sulfinpyrazone	ABCC3 ABCC5 ABCB4 SLC16A3 ABCC2	4.95e-05	87	104	5	CID000005342
Drug	dimethyl-beta-cyclodextrin	IFT172 ABCC2 ALDH3A2	4.97e-05	16	104	3	CID000122143
Drug	Chlorpheniramine	ABCB4 KCNH2 HRH1	4.97e-05	16	104	3	ctd:D002744
Drug	AC1L4BIC	ABCC3 ABCC5 ABCC2	4.97e-05	16	104	3	CID000153998
Drug	KC8851	KCNA2 KCNH2	6.18e-05	3	104	2	CID000065956
Drug	1,5-diphenyl-3-dimethylaminopyrrolidine	HRH1 HRH4	6.18e-05	3	104	2	CID003016476
Drug	Da-4626	HRH1 HRH4	6.18e-05	3	104	2	CID000134179
Drug	DA 4360	HRH1 HRH4	6.18e-05	3	104	2	CID000134176
Drug	Sotalol	ADRB1 KCNH2	6.18e-05	3	104	2	DB00489
Drug	illite	CLDN4 OCLN	6.18e-05	3	104	2	ctd:C099089
Drug	Terfenadine	KCNH2 HRH1	6.18e-05	3	104	2	DB00342
Drug	spirapril	SLC15A1 SLC15A2	6.18e-05	3	104	2	ctd:C052555
Drug	denopamine	ADRB1 KCNH2	6.18e-05	3	104	2	ctd:C037293
Drug	Lupitidinum	HRH1 HRH4	6.18e-05	3	104	2	CID000051670
Drug	AHR-9294	HRH1 HRH4	6.18e-05	3	104	2	CID000134395
Drug	AC1L61GL	HRH1 HRH4	6.18e-05	3	104	2	CID000284703
Drug	2,3,4,5-tetrahydro-1,5-benzothiazepine	HRH1 HRH4	6.18e-05	3	104	2	CID000093962
Drug	zatebradine	HCN2 KCNH2	6.18e-05	3	104	2	ctd:C043636
Drug	bilastine	HRH1 HRH4	6.18e-05	3	104	2	CID000185460
Drug	carbetapentane	ABCB4 KCNH2	6.18e-05	3	104	2	ctd:C018861
Drug	3-amino-4-methylfurazan	HRH1 HRH4	6.18e-05	3	104	2	CID000028674
Drug	plocamadiene A	HRH1 HRH4	6.18e-05	3	104	2	CID006441110
Disease	epilepsy (implicated_via_orthology)	SLC13A2 SLC1A5 SLC1A6 KCNA2 KCNH2 SCN2A ATP1A2	1.25e-06	163	98	7	DOID:1826 (implicated_via_orthology)
Disease	cystic fibrosis (implicated_via_orthology)	ABCB4 CLCN2 ABCC12	2.94e-06	9	98	3	DOID:1485 (implicated_via_orthology)
Disease	anemia (implicated_via_orthology)	SLC4A3 SLC4A1 SLC4A2	1.57e-05	15	98	3	DOID:2355 (implicated_via_orthology)
Disease	Primary biliary cirrhosis	IRF5 SLC4A2 ABCB4 ABCC2	1.83e-05	47	98	4	C0008312
Disease	short QT syndrome (implicated_via_orthology)	SLC4A3 KCNH2	3.27e-05	3	98	2	DOID:0050793 (implicated_via_orthology)
Disease	obsolete Mendelian syndromes with cleft lip/palate	GRM7 SPATA13 KLHL26	5.99e-05	23	98	3	MONDO_0015335
Disease	Cardiac Arrest	SLC4A3 KCNH2	1.08e-04	5	98	2	C0018790
Disease	Sjogren-Larsson syndrome (implicated_via_orthology)	ALDH3B1 ALDH3A2	1.62e-04	6	98	2	DOID:14501 (implicated_via_orthology)
Disease	Familial benign neonatal epilepsy	SCN2A ATP1A2	1.62e-04	6	98	2	C0220669
Disease	episodic ataxia type 6 (implicated_via_orthology)	SLC1A5 SLC1A6	1.62e-04	6	98	2	DOID:0050994 (implicated_via_orthology)
Disease	Schizophrenia	HTR4 MCHR2 GRM7 TRRAP SLC1A6 MTHFD1 KCNH2 HRH1 SLC17A7 ALDH3B1 KPNA3	1.70e-04	883	98	11	C0036341
Disease	Bipolar Disorder	HTR4 MCHR2 GRM7 SLC1A6 MTHFD1 SCN2A SLC17A7 ATP1A2	1.94e-04	477	98	8	C0005586
Disease	bilirubin metabolic disorder (biomarker_via_orthology)	ABCC3 ABCC2	2.27e-04	7	98	2	DOID:2741 (biomarker_via_orthology)
Disease	Rheumatoid Arthritis	ABCC3 ABCC5 IRF5 CXCR4 ABCC2	2.94e-04	174	98	5	C0003873
Disease	Cholestasis of pregnancy	ABCB4 ABCC2	3.02e-04	8	98	2	C0268318
Disease	Ventricular Fibrillation	SLC4A3 KCNH2	3.02e-04	8	98	2	C0042510
Disease	Pruritus	HRH1 HRH4	3.02e-04	8	98	2	C0033774
Disease	congestive heart failure (implicated_via_orthology)	RYR2 ADRB1 CXCR4	3.46e-04	41	98	3	DOID:6000 (implicated_via_orthology)
Disease	Generalized seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0234533
Disease	Clonic Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0234535
Disease	Convulsive Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0751494
Disease	Seizures, Sensory	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0751496
Disease	Non-epileptic convulsion	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0751056
Disease	Atonic Absence Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0751123
Disease	Complex partial seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0149958
Disease	Single Seizure	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0751110
Disease	Nonepileptic Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C3495874
Disease	Visual seizure	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0270824
Disease	Epileptic drop attack	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0270846
Disease	Vertiginous seizure	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0422855
Disease	Gustatory seizure	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0422854
Disease	Seizures, Somatosensory	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0422850
Disease	Olfactory seizure	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0422853
Disease	Seizures, Auditory	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0422852
Disease	Generalized Absence Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C4505436
Disease	pancreatic cancer (is_marker_for)	ABCC3 ABCC5 CLDN4 ABCC2	3.65e-04	101	98	4	DOID:1793 (is_marker_for)
Disease	Jacksonian Seizure	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C0022333
Disease	Epileptic Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.65e-04	101	98	4	C4317109
Disease	Secondary Biliary Cholangitis	SLC4A2 ABCB4 ABCC2	3.71e-04	42	98	3	C0238065
Disease	Biliary cirrhosis	SLC4A2 ABCB4 ABCC2	3.71e-04	42	98	3	C0023892
Disease	Biliary Cirrhosis, Primary, 1	SLC4A2 ABCB4 ABCC2	3.71e-04	42	98	3	C4551595
Disease	Absence Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.79e-04	102	98	4	C4316903
Disease	Convulsions	LETM1 KCNA2 SLC17A7 ABCC2	3.79e-04	102	98	4	C4048158
Disease	Tonic Seizures	LETM1 KCNA2 SLC17A7 ABCC2	3.79e-04	102	98	4	C0270844
Disease	cholestasis (implicated_via_orthology)	ABCB4 ABCC2	3.87e-04	9	98	2	DOID:13580 (implicated_via_orthology)
Disease	Seizures, Focal	LETM1 KCNA2 SLC17A7 ABCC2	4.08e-04	104	98	4	C0751495
Disease	Myoclonic Seizures	LETM1 KCNA2 SLC17A7 ABCC2	4.08e-04	104	98	4	C4317123
Disease	Tonic - clonic seizures	LETM1 KCNA2 SLC17A7 ABCC2	4.08e-04	104	98	4	C0494475
Disease	cholestasis (biomarker_via_orthology)	ABCC3 ABCB4 ABCC2	5.86e-04	49	98	3	DOID:13580 (biomarker_via_orthology)
Disease	late onset Parkinson's disease (is_implicated_in)	PSAP HLA-DRA	5.89e-04	11	98	2	DOID:0060892 (is_implicated_in)
Disease	Shortened QT interval	SLC4A3 KCNH2	5.89e-04	11	98	2	C0151879
Disease	Long QT Syndrome	RYR2 KCNH2	5.89e-04	11	98	2	C0023976
Disease	prediabetes syndrome (biomarker_via_orthology)	HLA-DRA SLC4A2	7.05e-04	12	98	2	DOID:11716 (biomarker_via_orthology)
Disease	Seizures	TRRAP LETM1 KCNA2 SLC17A7 ABCC2	8.18e-04	218	98	5	C0036572
Disease	glycochenodeoxycholate glucuronide (1) measurement	ABCC3 ABCC2	8.32e-04	13	98	2	EFO_0800474
Disease	iron deficiency anemia (biomarker_via_orthology)	SLC11A2 SLC4A1	8.32e-04	13	98	2	DOID:11758 (biomarker_via_orthology)
Disease	X-24588 measurement	ABCC3 ABCC2	8.32e-04	13	98	2	EFO_0800898
Disease	amenorrhea, response to antineoplastic agent	CALCR DERA	1.11e-03	15	98	2	EFO_0010269, GO_0097327
Disease	X-21441 measurement	ABCC3 ABCC2	1.44e-03	17	98	2	EFO_0800814
Disease	Tachycardia	HTR4 RYR2	1.61e-03	18	98	2	C0039231
Disease	Tachyarrhythmia	HTR4 RYR2	1.61e-03	18	98	2	C0080203
Disease	Cannabis use, age at onset	RYR2 ATP2C2	1.80e-03	19	98	2	EFO_0004847, EFO_0007585
Disease	electrocardiography	SLC4A3 LSM3 ADRB1 KCNA2 KCNH2 ATP1A2 NME7	1.97e-03	530	98	7	EFO_0004327
Disease	serum homoarginine measurement	GATM SLC15A1	2.00e-03	20	98	2	EFO_0005421
Disease	kidney disease (biomarker_via_orthology)	ABCC3 GATM	2.20e-03	21	98	2	DOID:557 (biomarker_via_orthology)
Disease	Colorectal Neoplasms	ABCC3 ABCC5 ABCB4 ABCA6 ABCC2	2.35e-03	277	98	5	C0009404
Disease	Colorectal Carcinoma	ABCC3 SLC11A2 ABCC5 GRID2 ABCB4 ABCA6 HRH1 ABCC2	2.37e-03	702	98	8	C0009402
Disease	Respiratory Hypersensitivity	CLDN4 HRH1	2.42e-03	22	98	2	C0035228
Disease	Anhedonia	SLC17A7 CCR7	2.87e-03	24	98	2	C0178417
Disease	body fat percentage, coronary artery disease	IGF2BP1 TMEM18	2.87e-03	24	98	2	EFO_0001645, EFO_0007800
Disease	systemic scleroderma	HLA-DRA IRF5 GRM7	2.88e-03	85	98	3	EFO_0000717
Disease	lung adenocarcinoma (is_marker_for)	SLC1A5 ADAM28 CXCR4	2.88e-03	85	98	3	DOID:3910 (is_marker_for)
Disease	Hereditary Diffuse Gastric Cancer	F2R ADRB1 SLC16A3 HRH4 DCBLD2	2.99e-03	293	98	5	C1708349
Disease	Cardiac Arrhythmia	HTR4 KCNH2	3.12e-03	25	98	2	C0003811
Disease	Stomach Neoplasms	F2R ADRB1 SLC16A3 HRH4 DCBLD2	3.17e-03	297	98	5	C0038356
Disease	Malignant neoplasm of stomach	F2R ADRB1 SLC16A3 HRH4 DCBLD2	3.30e-03	300	98	5	C0024623

Protein segments in the cluster

Peptide	Gene	Start	Entry
VNMFVIAGGTLAIPI	ABHD6	6	Q9BV23
VMGLLVVPFGATIVV	ADRB1	106	P08588
GDFGVPIAILIMVLV	SLC4A2	936	P04920
IIGDFGIPISILVMV	SLC4A3	926	P48751
VEGMNILGLVVFAIV	SLC1A5	226	Q15758
VFKVVPMLNPDGVIV	AGBL3	396	Q8NEM8
FQHIMVGLILPGIVI	CXCR4	201	P61073
FKNITVIQEPGMVVL	CPSF3	551	Q9UKF6
GDFGVPISILIMVLV	SLC4A1	606	P02730
SIVVGVLFPMAVIFV	ADAM28	666	Q9UKQ2
MIIIIHLVEVVPNGE	CALCR	196	P30988
MILVPLLGIQFVVFP	CALCR	346	P30988
MQEEIFGPILPIVNV	ALDH3B1	331	P43353
VFGIAIFPLIVENIM	ABCA6	861	Q8N139
FMGPVAVIILINLVF	ADGRE4P	341	Q86SQ3
ITIQVAQMVIGFLVP	CCR7	221	P32248
KVMQEEIFGPILPIV	ALDH3A2	326	P51648
LRPFVIVTANMILAV	CELSR1	2236	Q9NYQ6
AVAAIPEGLPIVVMV	ATP2C2	331	O75185
PQEAIAIVLGFMIIV	OCLN	241	Q16625
VAFMVLLIPLNGAVA	ABCC3	456	O15438
VIVGVVIPVLVVMVI	KIAA1549	1301	Q9HCM3
VIPVLVVMVIVVILY	KIAA1549	1306	Q9HCM3
QIQMVIDSGVVPFLV	KPNA3	276	O00505
VQAVIDAGLIPMIIH	KPNA3	361	O00505
FTNIMNIIDIVAIIP	KCNA2	251	P16389
IIVLGVIFMEGNCIP	MAGEA11	316	P43364
AVVIMLIVGIITPVF	LYSMD3	221	Q7Z3D4
ILIVVGNEIIEAPMA	GATM	171	P50440
SVMVLGLFVPPVFVV	SLC16A3	236	O15427
EMVQVFIPAQAVGAI	IGF2BP1	406	Q9NZI8
PLAVVDLIVDIMFIV	KCNH2	451	Q12809
VVVPFMEFLLPVAVK	LETM1	216	O95202
VVLRVVTVLEEPFVM	GRID2	441	O43424
MSAVPVGFFLLIVVL	LDAF1	61	Q96B96
FILLGLVQTEEMQPV	OR3A2	21	P47893
FILLGLVQTEEMQPV	OR3A3	21	P47888
GFSVPIVMVILDVIL	OR52B2	201	Q96RD2
LIAMVDVIFADVAQP	FBL	226	P22087
NIPMLFVRGDGVVLV	LSM3	81	P62310
GFLAARAQLPVMVIV	NOL6	936	Q9H6R4
PQIEQAVGIVGAVIM	SLC11A2	251	P49281
IVIPLGIIYVSVQMF	ABCC2	1126	Q92887
VQVVPVAARLLLEMF	IRF5	416	Q13568
EVVVLIVVGINIMVP	OR8B3	196	Q8NGG8
LEMAVVLFVVPLIIT	GPR42	186	O15529
NMEVVLAVGPQLIGI	IFT172	1331	Q9UG01
VPPESVDVVMLIFVL	METTL6	146	Q8TCB7
LAVVPIIAVSGIVEM	ABCB4	861	P21439
GVFVVSLPLNIMAIV	F2R	111	P25116
GLVVPVIRNVEAMNF	DLST	326	P36957
AVADLVHIVGMPFLI	MCHR2	76	Q969V1
PVVAILGMIYNVIIL	ABCC5	301	O15440
LVVFIVVAVDVGMPI	OR8B12	196	Q8NGG6
VVAVDVGMPIVTVFI	OR8B12	201	Q8NGG6
PIAMEIEHFIQLITG	ATP1A2	281	P50993
MGELFIPSVNLVVAE	IGSF5	141	Q9NSI5
VSIMVANVLRLFAIP	GRM6	156	O15303
VLGAAVFLQMLPVVE	KLHL26	136	Q53HC5
RPVFIMVEKLVQIHG	CCDC81	76	Q6ZN84
GFSVFIQLMPIIVLI	DNAJB14	246	Q8TBM8
LEMAVVLFVVPLIIT	FFAR3	186	O14843
DLLVSVLVMPFGAIE	HTR4	66	Q13639
VLVMPFGAIELVQDI	HTR4	71	Q13639
IAVFIGILMVTIIHP	SLC1A6	141	P48664
VPVLGFFIIAVLMSA	HLA-DRA	6	P01903
AVIPVFLAMLGIIAT	GRM7	591	Q14831
VVLPIVIITFFVGMI	EMC3	16	Q9P0I2
HIIVVLDPVLLQMEG	EME1	251	Q96AY2
DVALAAVLVPVLVMV	DCBLD2	526	Q96PD2
VADLIVGAVVMPMNI	HRH1	71	P35367
VNATFPVAIVMLRAI	DERA	226	Q9Y315
IIIFIPADLPVVVTM	SLC22A13	406	Q9Y226
GTVAIFIGIIMFIIP	SLC13A2	371	Q13183
QTVNAILIVIMVPIF	SLC15A1	326	P46059
FGVPGLLMVIALVVF	SLC15A2	221	Q16348
IIPMIQGFVQIEELV	INPP5F	231	Q9Y2H2
DLVGVISIAFQMPTI	RYR2	2431	Q92736
FMVGNLIIIPVGITF	HCN2	221	Q9UL51
QIENARMFGIPVVVA	MTHFD1	741	P11586
QFITTGPIIAMEILR	NME7	151	Q9Y5B8
MEFGALEIIPVVITF	COL6A6	1886	A6NMZ7
ILTGNLIMFIVIQVG	OR6K6	66	Q8NGW6
IINFVVRLFVILVPM	OR10J6P	196	Q8NGY7
RIFILIVAGMVIATP	OR1M1	196	Q8NGA1
QLVIFMLGVFALVIP	OR10K1	196	Q8NGX5
MVFVLGGTVLIVPFL	OR1N1	196	Q8NGS0
VLAFLVNGPMILVSE	HRH4	141	Q9H3N8
LQRVVLAFMVPLGVI	RXFP4	206	Q8TDU9
KVFGIVIPMQVLANV	GPR108	366	Q9NPR9
VIPMQVLANVAYIII	GPR108	371	Q9NPR9
MTIIVPIGGQIADFL	SLC17A7	351	Q9P2U7
MVVFILVILAAVFPA	ABCC12	936	Q96J65
AGVVFLLAGLMVIVP	CLDN4	121	O14493
VFELTGQIAHILPVM	CLCN2	521	P51788
QMIDIAIDGFLLTPV	SPATA13	366	Q96N96
GVLFPTVEMVIKVFV	SH3BGR	56	P55822
TPLAADFGVILVIMV	SLC17A2	136	O00624
LVNLVVMDPFVDLAI	SCN2A	751	Q99250
GVLAVLMIAAFLQPI	UNC93A	211	Q86WB7
TVFVQGMTIRPLVDL	SLC9A1	491	P19634
LGVNVGSLMVPVFVV	TMUB2	266	Q71RG4
GSLMVPVFVVLLGVV	TMUB2	271	Q71RG4
VLIEILVEVMDPSFV	PSAP	461	P07602
VVVQELMVLPAVAAP	ZNF853	441	P0CG23
GPVLIITFQAQLVMV	TIMM44	386	O43615
VMVVNGIVIVLNPDV	TAS2R8	61	Q9NYW2
EVPLGRVVLMVFSLV	XKRX	196	Q6PP77
VVAEFVPLIMNTIAI	TRRAP	246	Q9Y4A5
VFSAPLLVNAMIIVV	TMEM18	96	Q96B42
SIIMSVVVFVPGNIV	TM6SF1	146	Q9BZW5