Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

5.39e-08431187GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

4.21e-07884188GO:0004930
GeneOntologyMolecularFunctionodorant binding

OR5W2 OR6B2 OR5AS1 OR6B3

4.46e-06127184GO:0005549
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

1.03e-051353188GO:0004888
GeneOntologyMolecularFunctionubiquitin binding

RAE1 HDAC6

4.12e-03107182GO:0043130
GeneOntologyMolecularFunctionubiquitin-like protein binding

RAE1 HDAC6

5.83e-03128182GO:0032182
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

4.39e-08432187GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

7.26e-08465187GO:0007608
GeneOntologyBiologicalProcesssensory perception

OR1F1 OR5W2 OR6B2 OTOGL OR6C2 SPRY2 OR5AS1 OR6B3 OR6C74

8.50e-081072189GO:0007600
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

9.68e-08485187GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

1.64e-07524187GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.19e-07547187GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

3.34e-07582187GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

1.42e-06722187GO:0051606
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

1.02e-051395188GO:0007186
GeneOntologyBiologicalProcessdevelopmental growth

MYCBP2 SPRY2 ZFPM2 ITGA4 HDAC6

8.80e-04911185GO:0048589
DomainOlfact_rcpt

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.81e-08393177IPR000725
DomainGPCR_Rhodpsn_7TM

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

4.80e-08670178IPR017452
Domain7tm_1

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

5.20e-08677178PF00001
DomainG_PROTEIN_RECEP_F1_1

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

5.70e-08685178PS00237
DomainG_PROTEIN_RECEP_F1_2

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

6.10e-08691178PS50262
DomainGPCR_Rhodpsn

OR1F1 OR5W2 GPR32 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

6.17e-08692178IPR000276
DomainWD40_repeat_CS

RAE1 BRWD1

9.56e-03164172IPR019775
DomainWD40

RAE1 BRWD1

2.27e-02259172PF00400
DomainWD40

RAE1 BRWD1

2.42e-02268172SM00320
DomainWD40_repeat

RAE1 BRWD1

2.49e-02272172IPR001680
DomainWD_REPEATS_1

RAE1 BRWD1

2.59e-02278172PS00678
DomainWD_REPEATS_2

RAE1 BRWD1

2.61e-02279172PS50082
DomainWD_REPEATS_REGION

RAE1 BRWD1

2.61e-02279172PS50294
DomainWD40_repeat_dom

RAE1 BRWD1

2.93e-02297172IPR017986
PathwayREACTOME_SENSORY_PERCEPTION

OR1F1 OR5W2 OR6B2 OTOGL OR6C2 OR5AS1 OR6B3 OR6C74

1.53e-07636168M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

1.71e-07417167M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR1F1 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.69e-06389166M14091
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.33e-1034018711875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.33e-1034018711802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.47e-1034318732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR1F1 OR5W2 OR6B2 OR6C2 OR5AS1 OR6B3 OR6C74

2.63e-1034618714611657
Pubmed

The human olfactory receptor gene family.

OR1F1 OR5W2 OR6B2 OR5AS1 OR6B3 OR6C74

2.18e-0754118614983052
Pubmed

RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans.

RAE1 MYCBP2

2.53e-07218222357847
Pubmed

Functional and comparative genomic analysis of the piebald deletion region of mouse chromosome 14.

MYCBP2 SPRY2

1.14e-051018212160731
Pubmed

USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.

RAE1 MYCBP2

1.66e-051218229293652
Pubmed

The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.

OR1F1 OR6C2

6.36e-052318210706615
Pubmed

Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.

OR6C2 OR6C74

6.94e-052418224152035
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

MYCBP2 ZFPM2

1.17e-043118227321927
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

RAE1 MYCBP2 BRWD1

1.63e-0420918326389662
Pubmed

Epicardial-myocardial signaling directing coronary vasculogenesis.

ZFPM2 ITGA4

1.67e-043718220299672
Pubmed

14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation.

RAE1 MYCBP2

2.15e-044218223444366
Pubmed

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity.

MYCBP2 HDAC6

2.36e-044418222645275
Pubmed

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.

RAE1 MYCBP2

5.16e-046518228276505
InteractionEFHD2 interactions

RAE1 MYCBP2 HDAC6

5.16e-05127123int:EFHD2
InteractionMYO10 interactions

RAE1 MYCBP2 HDAC6

7.04e-05141123int:MYO10
InteractionDSCR9 interactions

MYCBP2 SPRY2 HDAC6

7.97e-05147123int:DSCR9
InteractionNUP188 interactions

RAE1 ZNF330 ITGA4

8.13e-05148123int:NUP188
InteractionSYT3 interactions

MYCBP2 HDAC6

1.13e-0427122int:SYT3
InteractionRAN interactions

RAE1 MYCBP2 ITGA4 HDAC6

1.30e-04475124int:RAN
InteractionDYNC1H1 interactions

RAE1 MYCBP2 ITGA4 HDAC6

1.47e-04491124int:DYNC1H1
InteractionARPC3 interactions

MYCBP2 ITGA4 HDAC6

1.53e-04183123int:ARPC3
InteractionTESK1 interactions

MYCBP2 SPRY2

1.60e-0432122int:TESK1
InteractionRPS4X interactions

ZNF330 ITGA4 HDAC6 BRWD1

2.13e-04540124int:RPS4X
InteractionABLIM3 interactions

MYCBP2 HDAC6

2.38e-0439122int:ABLIM3
InteractionH4C15 interactions

ZNF330 ITGA4

2.76e-0442122int:H4C15
InteractionBUB3 interactions

RAE1 ITGA4 HDAC6

3.07e-04232123int:BUB3
InteractionNUP205 interactions

RAE1 ZNF330 ITGA4

3.19e-04235123int:NUP205
InteractionICAM4 interactions

MYCBP2 ITGA4

3.32e-0446122int:ICAM4
InteractionLCOR interactions

MYCBP2 ZNF330 HDAC6

3.47e-04242123int:LCOR
Cytoband12q13.2

OR6C2 OR6C74

2.13e-045518212q13.2
Cytoband2q37.3

OR6B2 OR6B3

4.17e-04771822q37.3
CytobandEnsembl 112 genes in cytogenetic band chr2q37

OR6B2 OR6B3

3.50e-03226182chr2q37
CytobandEnsembl 112 genes in cytogenetic band chr11q12

OR5W2 OR5AS1

7.96e-03345182chr11q12
CytobandEnsembl 112 genes in cytogenetic band chr12q13

OR6C2 OR6C74

1.18e-02423182chr12q13
GeneFamilyOlfactory receptors, family 6

OR6B2 OR6C2 OR6B3 OR6C74

7.49e-0851154153
GeneFamilyOlfactory receptors, family 5

OR5W2 OR5AS1

3.79e-03112152152
GeneFamilyWD repeat domain containing

RAE1 BRWD1

1.94e-02262152362
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF330 ZNF578 ZFPM2

1.99e-0271815328
Diseaseschizophrenia, type 2 diabetes mellitus

MYCBP2 SPRY2

2.78e-0443172MONDO_0005090, MONDO_0005148
Diseasediabetes mellitus

MYCBP2 SPRY2

6.96e-0468172EFO_0000400

Protein segments in the cluster

PeptideGeneStartEntry
NGCTHCYLAFNSDNE

GPR32

186

O75388
CCFNHNGNIFAYASS

RAE1

321

P78406
FCDSNAIDHFSCDAG

OR6C2

166

Q9NZP2
LCFCGSNEINHFFCD

OR5W2

166

Q8NH69
AAFRCNHCHFGFQTQ

ZFPM2

361

Q8WW38
LSFCGSNIVNHFFCD

OR5AS1

166

Q8N127
FCAANTVDHFFCDVS

OR6C74

166

A6NCV1
LSFCADNAITHFFCD

OR1F1

166

O43749
DCKFSQDGQHFACTD

BRWD1

521

Q9NSI6
INFARFCAHENCSAD

ITGA4

616

P13612
HAEQDAACGFCFFNS

HDAC6

611

Q9UBN7
EFTAIDHNFQSDCGC

OTOGL

2091

Q3ZCN5
VTFCGSNVLNHFFCD

OR6B2

166

Q6IFH4
AVFFCFGTTHFCNAC

MYCBP2

4606

O75592
FGTTHFCNACHDDFQ

MYCBP2

4611

O75592
VTFCGSNVLNHFFCD

OR6B3

166

Q8NGW1
FYHCSNDDEDNCADN

SPRY2

226

O43597
FQCNETGEAFNCSSF

ZNF578

231

Q96N58
CSFCHNFLCEDDQFE

ZNF330

146

Q9Y3S2