Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionH3K27me3 modified histone binding

TAF1 TAF1L

7.68e-055562GO:0061628
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

SNIP1 TAF1 TAF1L

1.40e-0436563GO:0140416
GeneOntologyMolecularFunctionRNA polymerase I general transcription initiation factor activity

TAF1 TAF1L

2.75e-049562GO:0001181
DomainNBPF_dom

NBPF9 NBPF11 NBPF14

4.14e-0611563IPR010630
DomainNBPF

NBPF9 NBPF11 NBPF14

4.14e-0611563PS51316
DomainDUF1220

NBPF9 NBPF11 NBPF14

4.14e-0611563PF06758
DomainTAF_II_230-bd

TAF1 TAF1L

8.83e-062562IPR009067
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

8.83e-062562IPR022591
Domain-

TAF1 TAF1L

8.83e-0625621.10.1100.10
DomainTBP-binding

TAF1 TAF1L

8.83e-062562PF09247
DomainDUF3591

TAF1 TAF1L

8.83e-062562PF12157
DomainTAF1_animal

TAF1 TAF1L

8.83e-062562IPR011177
Domain-

EMC1 EIF2AK3

1.31e-0465622.140.10.10
DomainQuinoprotein_ADH-like_fam

EMC1 EIF2AK3

1.31e-046562IPR027295
DomainDUF1220

NBPF9 NBPF11

3.14e-049562SM01148
DomainDynein_HC_stalk

DNHD1 DNAH8

7.85e-0414562IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH8

7.85e-0414562IPR013602
DomainDHC_N2

DNHD1 DNAH8

7.85e-0414562PF08393
DomainMT

DNHD1 DNAH8

7.85e-0414562PF12777
DomainDHC_fam

DNHD1 DNAH8

9.04e-0415562IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH8

9.04e-0415562IPR004273
DomainDynein_heavy

DNHD1 DNAH8

9.04e-0415562PF03028
DomainBromodomain_CS

TAF1 TAF1L

2.74e-0326562IPR018359
DomainAbhydrolase_1

SERHL2 SERHL

3.88e-0331562PF00561
DomainAB_hydrolase_1

SERHL2 SERHL

4.39e-0333562IPR000073
DomainBROMODOMAIN_1

TAF1 TAF1L

5.50e-0337562PS00633
DomainBromodomain

TAF1 TAF1L

5.79e-0338562PF00439
Domain-

DNHD1 ABCA12 IFI44 CMPK2 RAB15 GFM1 DNAH8

6.67e-037465673.40.50.300
DomainBROMODOMAIN_2

TAF1 TAF1L

6.72e-0341562PS50014
DomainBROMO

TAF1 TAF1L

7.04e-0342562SM00297
DomainBromodomain

TAF1 TAF1L

7.04e-0342562IPR001487
Domain-

TAF1 TAF1L

7.04e-03425621.20.920.10
DomainNeurotransmitter_ion_chnl_CS

GLRB HTR3E

8.05e-0345562IPR018000
DomainNeur_chan_memb

GLRB HTR3E

8.40e-0346562PF02932
DomainNeur_chan_LBD

GLRB HTR3E

8.75e-0347562PF02931
DomainNEUROTR_ION_CHANNEL

GLRB HTR3E

8.75e-0347562PS00236
DomainNeurotrans-gated_channel_TM

GLRB HTR3E

8.75e-0347562IPR006029
Domain-

GLRB HTR3E

8.75e-03475622.70.170.10
DomainNeur_channel

GLRB HTR3E

8.75e-0347562IPR006201
DomainNeur_chan_lig-bd

GLRB HTR3E

8.75e-0347562IPR006202
DomainQuinoprotein_ADH-like_supfam

EMC1 EIF2AK3

1.10e-0253562IPR011047
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF8 NBPF12 NBPF9 NBPF10 NBPF11 NBPF14 NBPF20

4.60e-152162716079250
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF12 NBPF9 NBPF14

1.91e-091062422973535
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NBPF8 DOCK5 NBPF12 ABCA12 NBPF9 NBPF10 NBPF11 TECTA NBPF14 EIF2AK3

2.42e-08513621025798074
Pubmed

Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.

TGFBR2 TAF1 TAF1L

1.07e-07662319959467
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF8 NBPF12 NBPF9 NBPF10 NBPF11 NBPF14

6.12e-0717062623314748
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

3.13e-06262238804708
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

3.13e-06262210070062
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

3.13e-06262222842574
Pubmed

Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.

SERHL2 SERHL

3.13e-06262211352564
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

3.13e-06262227571988
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

3.13e-06262234403156
Pubmed

Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.

TGFBR2 EBF1

9.37e-06362220214815
Pubmed

TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.

TAF1 TAF1L

9.37e-06362211592977
Pubmed

Regulated expression of TAF1 in 1-cell mouse embryos.

TAF1 TAF1L

9.37e-06362216822332
Pubmed

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

TAF1 TAF1L

9.37e-06362212217962
Pubmed

TAF7: a possible transcription initiation check-point regulator.

TAF1 TAF1L

9.37e-06362216407123
Pubmed

Two new mutations in linkage group XVI of the house mouse. Flaky tail and varitint-waddler-J.

GLRB TMEM79

4.67e-0566224557539
Pubmed

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

TAF1 TAF1L

8.69e-0586222034279
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TRIM5

8.69e-05862210331952
Pubmed

Genetic mapping in the region of the mouse X-inactivation center.

TAF1 TAF1L

8.69e-0586221974879
Pubmed

Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.

TAF1 TAF1L

8.69e-05862231012985
Pubmed

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.

TAF1 TAF1L

8.69e-0586228468051
Pubmed

High-density molecular map of the central span of the mouse X chromosome.

TAF1 TAF1L

8.69e-0586221675191
Pubmed

Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

TAF1 TAF1L

1.12e-0496227874112
Pubmed

The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.

TAF1 TAF1L

1.12e-04962212665565
Pubmed

HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.

TAF1 TAF1L

1.12e-0496229751712
Pubmed

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

RGMA UNC5D

1.12e-04962223457482
Pubmed

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

TAF1 TAF1L

1.39e-04106222055107
Pubmed

Characterization of a murine gene expressed from the inactive X chromosome.

TAF1 TAF1L

1.70e-04116222034278
Pubmed

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

TAF1 TAF1L

2.41e-04136227805729
Pubmed

Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.

TAF1 TAF1L

2.41e-04136228012115
Pubmed

Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.

TAF1 TAF1L

2.41e-041362211557891
Pubmed

Rps4 maps near the inactivation center on the mouse X chromosome.

TAF1 TAF1L

2.41e-04136221740345
Pubmed

XIST and the mapping of the X chromosome inactivation centre.

TAF1 TAF1L

2.41e-04136221772416
Pubmed

Gene order in linkage group XVI of the house mouse.

GLRB TMEM79

2.41e-0413622489953
Pubmed

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3.

FAM120A G3BP1 HECTD4 PRRC2A

2.69e-0417462435031058
Pubmed

TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf.

TGFBR2 IL6ST

2.81e-041462238427718
Pubmed

The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.

TAF1 TAF1L

3.23e-041562214580349
Pubmed

Voxelwise genome-wide association study (vGWAS).

EMC1 FRMD6

3.23e-041562220171287
Pubmed

Functional redundancy of frizzled 3 and frizzled 6 in planar cell polarity control of mouse hair follicles.

SERHL2 SERHL

3.23e-041562230237242
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

SNIP1 EBF1 TAF1 TAF1L

3.83e-0419162424146773
Pubmed

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

DIP2B SLC25A28

4.18e-041762224737748
Pubmed

Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.

NFASC TRIM5

4.70e-041862231910261
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

FAM120A G3BP1 CFAP20 RAVER2 NBPF10 PRRC2A NOVA1

5.73e-0480762722681889
Pubmed

A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

MAN2B2 IFI44 DNAH8 IL6ST

6.30e-0421862419460752
Pubmed

GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.

DNHD1 TRIM5

7.72e-042362223725790
Pubmed

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.

RGMA UNC5D

8.41e-042462226633881
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

TGFBR2 HDX EBF1 UNC5D

1.06e-0325162429031500
Pubmed

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.

NFASC TRIM5

1.07e-032762234709416
Pubmed

Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.

RGMA NOVA1

1.07e-032762225133637
Pubmed

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

GLRB NOVA1

1.07e-032762223359859
Pubmed

Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.

FRMD6 EBF1

1.23e-032962231491374
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

TMEM67 EMC1 MAN2B2 FKBP9 RER1 NBPF26 EIF2AK3 IL6ST

1.28e-03120162835696571
Pubmed

Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.

FAM120A G3BP1

1.32e-033062215782174
Pubmed

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.

TAF1 TAF1L

1.41e-033162225838543
Pubmed

Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.

PTCH2 EBF1

1.50e-033262214973295
Pubmed

Reevaluating human gene annotation: a second-generation analysis of chromosome 22.

SERHL2 SERHL

1.59e-033362212529303
Pubmed

Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum.

EBF1 UNC5D

1.59e-033362218199763
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DIP2B PASK EMC1 FAM120A PPP2R3B GFM1 PRRC2A

1.70e-0397462728675297
InteractionNEK4 interactions

NBPF8 DOCK5 NBPF12 ABCA12 NBPF9 NBPF10 NBPF11 TECTA NBPF14 EIF2AK3

8.95e-065826110int:NEK4
Cytoband1q21.1

NBPF8 NBPF9 NBPF10 NBPF11 NBPF14

2.32e-08626251q21.1
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NBPF12 NBPF9 NBPF10 NBPF11 NBPF14 NBPF20

1.81e-05404626chr1q21
CytobandEnsembl 112 genes in cytogenetic band chr1p11

NBPF8 NBPF26

3.71e-0421622chr1p11
Cytoband3q27.1

MCF2L2 HTR3E

6.16e-04276223q27.1
GeneFamilyNeuroblastoma breakpoint family

NBPF8 NBPF12 NBPF9 NBPF10 NBPF26 NBPF11 NBPF14 NBPF20

5.14e-1723368662
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL6ST CXCR1

3.16e-0342362602
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

RGMA SERHL2 NBPF12 SERHL NBPF26 NBPF11 NBPF14 IL6ST

3.16e-06320608PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NBPF8 NBPF10 TAF1 SLC25A28 NBPF20

4.55e-06175625a3f8c54c77bce9b035a4835945ab341909be4946
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

NBPF10 IFI44 CMPK2 NBPF11 IL6ST

5.50e-06182625877b6e611626628e709568747512f2827ebb2795
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGMA TENM4 FRMD6 EBF1 NOVA1

5.50e-06182625fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGMA TENM4 FRMD6 EBF1 NOVA1

5.96e-061856258f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA DOCK5 NBPF10 NBPF26 NBPF14

6.28e-061876254d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGMA TENM4 FRMD6 EBF1 NOVA1

6.44e-06188625fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

G3BP1 FRMD6 NFASC EBF1 IL6ST

6.78e-061906251121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

G3BP1 FRMD6 NFASC EBF1 IL6ST

6.78e-06190625048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

RGMA TENM4 FRMD6 EBF1 NOVA1

7.50e-06194625d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

RGMA TENM4 FRMD6 EBF1 NOVA1

7.69e-06195625f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellmild-CD8+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TGFBR2 PASK IFI44 CMPK2 IL6ST

8.70e-06200625c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCellControl-B_activate-7|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TENM4 IFI44 CMPK2 RAB15

3.26e-05130624d3343c19d61928f18e7d707eda5dec6e0fd2a9a2
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

PASK IFI44 CMPK2 RAB15

6.00e-05152624b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

PASK GMCL1 IFI44 CMPK2

6.47e-051556247e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCellCOVID-19-kidney-Lymphatic_EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK5 TGFBR2 FRMD6 EBF1

8.64e-0516762497d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR2 MAN2B2 FRMD6 RAB3IL1

9.90e-0517362403b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR2 MAN2B2 FRMD6 RAB3IL1

9.90e-0517362412da47b90aecedaa31764ff7ddb853ee39123e9d
ToppCellPND28-Endothelial-Endothelial_lymphatic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR2 MAN2B2 FRMD6 RAB3IL1

9.90e-051736242978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLRB HDX RAB3IL1 IL6ST

9.90e-0517362485083b9ce20351dd69aa2327ad087b848b4307ff
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBR2 MAN2B2 FRMD6 RAB3IL1

9.90e-0517362423d4a315a0ad5c6fc77bcfc18b6c1ff55be99e8f
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK5 TGFBR2 FRMD6 EBF1

1.08e-04177624326fde0734ef0d7272693966d346ca479b9d8147
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 TGFBR2 FRMD6 IL6ST

1.10e-04178624ad3de3e03a401dac64431a541899445262246347
ToppCellCOVID-19_Convalescent|World / Disease condition and Cell class

PTCH2 NBPF26 NBPF14 NBPF20

1.18e-04181624a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

SERHL2 PPP2R3B EBF1 EIF2AK3

1.20e-04182624a5fd392178c2f533e265d2e3ce63b90c2553e4c1
ToppCellIIH-Treg-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

G3BP1 TMEM79 NBPF26 NBPF20

1.20e-041826245c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 TGFBR2 FRMD6 IL6ST

1.20e-0418262453c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

TGFBR2 IFI44 CMPK2 EBF1

1.23e-041836243c4153479fc4ab2d073d92cee120480015555914
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 TGFBR2 FRMD6 IL6ST

1.23e-041836244d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CMPK2 SLC25A28 DNAH8 TRIM5

1.23e-04183624dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

DOCK5 IFI44 CMPK2 DNAH8

1.23e-04183624bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TENM4 PTCH2 NBPF26 EBF1

1.25e-041846244d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 TGFBR2 FRMD6 IL6ST

1.31e-0418662440070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellmild-unassigned|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PASK TMEM79 MCF2L2 CXCR1

1.31e-041866245b2e1a58916f392fa1156bf9210df528775248ff
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 TGFBR2 FRMD6 IL6ST

1.31e-0418662420340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NBPF8 TENM4 DNAH8 UNC5D

1.31e-0418662423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HDX IFI44 CMPK2 TRIM5

1.34e-0418762472e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA NBPF10 NBPF26 NBPF14

1.34e-04187624dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA NBPF10 NBPF26 NBPF14

1.34e-04187624ae90c263f80c36a410150d499e268d198944a3d9
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK5 FRMD6 NFASC EBF1

1.36e-041886242db80767903703e7e0a1a37c598f7877a909ee94
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM67 PTCH2 EBF1 EIF2AK3

1.39e-04189624b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

RGMA FRMD6 EBF1 NOVA1

1.42e-041906247dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

IFI44 CMPK2 SLC25A28 TRIM5

1.45e-041916242da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRMD6 PTCH2 EBF1 NOVA1

1.48e-041926248d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

TENM4 FRMD6 EBF1 NOVA1

1.48e-0419262460b1312e84f6d6448365a952469c506c00b5fe93
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGMA FRMD6 EBF1 NOVA1

1.48e-04192624e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

RGMA FRMD6 EBF1 NOVA1

1.48e-04192624d21f0f577156f17c899b08871046a26b88aea011
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TENM4 FRMD6 IFI44 EBF1

1.48e-04192624d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGMA FRMD6 EBF1 NOVA1

1.51e-041936249ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TENM4 PTCH2 EBF1 NOVA1

1.51e-04193624549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HDX IFI44 CMPK2 SLC25A28

1.51e-0419362422455801194bd8c73c5c397f5eac4f723429c383
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD6 PTCH2 NFASC EBF1

1.54e-0419462481713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

HDX IFI44 CMPK2 TRIM5

1.54e-04194624e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD6 PTCH2 NFASC EBF1

1.54e-04194624627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DOCK5 TGFBR2 FRMD6 EBF1

1.57e-04195624e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

IFI44 CMPK2 SLC25A28 TRIM5

1.57e-04195624b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

TENM4 IFI44 NFASC UNC5D

1.60e-041966249401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTCH2 NBPF26 EBF1 IL6ST

1.63e-041976245fbbc570a4e77c703f569a4f85ce2d8af67d6297
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD6 NFASC EBF1 IL6ST

1.63e-041976249b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

DOCK5 FRMD6 GLRB RAB3IL1

1.63e-04197624c838d0f64e3b43a616a9e381b8139bfe9aa32da7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRMD6 NFASC EBF1 IL6ST

1.66e-04198624a860246bcea847249a78fd2e86ed8e04371060db
ToppCell367C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RGMA EBF1 RAB3IL1 NOVA1

1.69e-041996242aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCell367C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RGMA EBF1 RAB3IL1 NOVA1

1.69e-04199624c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 TGFBR2 FRMD6 GLRB

1.73e-0420062476e90231aa94afc12e618da8ae314c51644acab4
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DOCK5 IFI44 PTCH2 NBPF14

1.73e-04200624934c2efc780318c66d667ca75be0de350361d351
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

TGFBR2 IFI44 CMPK2 NOVA1

1.73e-04200624be55cef682ba87250dad97689332c8820b3a7420
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 TGFBR2 FRMD6 GLRB

1.73e-04200624e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
DrugPesticides

NBPF8 NBPF12 NBPF9 NBPF10 NBPF11 NBPF14 NBPF20

1.35e-07150607ctd:D010575
Diseaseserum gamma-glutamyl transferase measurement

TENM4 CFAP20 HDX HECTD4 EBF1 SLC25A28 RAB3IL1 PRRC2A

3.13e-04914568EFO_0004532
DiseaseChild Behaviour Checklist assessment

TENM4 G3BP1

5.31e-0418562EFO_0005661
Diseasepseudotumor cerebri

RGMA CXCR1

1.12e-0326562EFO_1001132
Diseaselifestyle measurement, alcohol consumption measurement

RGMA EBF1 UNC5D

1.38e-03115563EFO_0007878, EFO_0010724
Diseaseglutamate measurement

TAF1L UNC5D

1.39e-0329562EFO_0010487
DiseaseHbA1c measurement

DIP2B FIG4 TMEM79 EBF1 UNC5D TRIM5

1.72e-03675566EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
YRGQLYLQSSVRISE

EIF2AK3

391

Q9NZJ5
GNLYDQIVFYVAIRR

HTR3E

231

A5X5Y0
IYGRAFIYLQDSIER

ABCA12

1016

Q86UK0
TLTREQARLGYYQFQ

DNHD1

3356

Q96M86
FGFDLLVTYTNRYII

GMCL1

416

Q96IK5
FTYIRYIQQGLVRQD

RAB3IL1

341

Q8TBN0
QTITKQYYRRAQGIF

RAB15

71

P59190
LVRAYGNIERCFLVY

RAVER2

161

Q9HCJ3
YITTVIQRIFYAVNR

PPP2R3B

261

Q9Y5P8
YYATVTLDQVRNILR

C9orf64

121

Q5T6V5
SYIFRQLVSAVGYLR

PASK

1106

Q96RG2
VFTVEQQRILQRYYE

HDX

6

Q7Z353
RRAYGTNYIETLRVQ

CFAP20

141

Q9Y6A4
AVIYGLLNENFRREY

GPR50

291

Q13585
IQRTFTDIGIKYYRN

MCF2L2

141

Q86YR7
YVYIFSAVLRISQRQ

OR14K1

216

Q8NGZ2
IAGYQIFQITLTRSY

DNAH8

2836

Q96JB1
VYRGRIAVFSVSVFY

DIP2B

841

Q9P265
VTAYFRGVQARVIYQ

SLC25A28

321

Q96A46
GYYTCVEVIFTLRRQ

GLRB

251

P48167
RQYVYGVLFSLAESR

FAM120A

606

Q9NZB2
QVETYLRSEGVLVRY

HECTD4

2386

Q9Y4D8
YRRYFTQIVGFFVVE

EXOC6

331

Q8TAG9
RNRTFDTYIGQGYVI

FKBP9

301

O95302
RLSPYVNYQFRVIAI

NFASC

691

O94856
FRVQYYVENGRLISD

FRMD6

111

Q96NE9
IIRRAFYSLGNYIVA

CMPK2

301

Q5EBM0
VQNGFIRNYTIFYRT

IL6ST

546

P40189
IRNYTIFYRTIIGNE

IL6ST

551

P40189
DIFYILNGNIRDRYQ

IFI44

266

Q8TCB0
FIIQSRVLYLRFYGQ

DOCK5

766

Q9H7D0
VLYETRARYFLVGSN

FIG4

16

Q92562
VGREFVRQYYTLLNQ

G3BP1

11

Q13283
YFRLNTLASLGYVVV

DPP8

686

Q6V1X1
YSRVGRSVTDVYLLN

CXCR1

66

P25024
YSNGIRTEQDFYVRL

EBF1

116

Q9UH73
AGQLVTEIRQYFYRN

MAN2B2

656

Q9Y2E5
QTYTINLYLVETGRR

EMC1

371

Q8N766
EVGRFGQLTYVRSYQ

GFM1

361

Q96RP9
YYLQTFVSEIRRVVA

SERHL2

81

Q9H4I8
YLITQRITYEQGVRA

NOVA1

486

P51513
SFLTYLQQEIFRYIR

TMEM67

961

Q5HYA8
YYLQTFVSEIRRVVA

SERHL

81

Q9NQF3
SVVYRFFTRLGQIYQ

RER1

16

O15258
FQYRLVEYTRADGTV

SNIP1

306

Q8TAD8
YRSAFYILEQQRVGL

NBPF8

621

Q3BBV2
YRSAFYVLEQQRVGL

NBPF9

656

P0DPF3
YRSAFYILEQQRVGL

NBPF10

656

Q6P3W6
YRSAFYVLEQQRIGL

NBPF11

656

Q86T75
YRSAFYVLEQQRVGL

NBPF12

1171

Q5TAG4
YRSAFYVLEQQRVGL

NBPF14

316

Q5TI25
YRSAFYVLEQQRIGL

NBPF20

41

P0DPF2
YRSAFYVLEQQRVGL

NBPF20

1261

P0DPF2
YRSAFYVLEQQRVGL

NBPF20

2481

P0DPF2
YRSAFYVLEQQRVGL

NBPF20

3701

P0DPF2
YRSAFYVLEQQRVGL

NBPF20

4921

P0DPF2
YRSAFYVLEQQRVGL

NBPF26

316

B4DH59
YRSAFYILEQQRVGL

NBPF26

391

B4DH59
YRSAFYILEQQRVGL

NBPF26

466

B4DH59
YRSAFYILEQQRVGL

NBPF26

541

B4DH59
YRSAFYILEQQRVGL

NBPF26

616

B4DH59
TRQGYYIRELVDIFV

TAF1L

786

Q8IZX4
RTRQGYYIRELVDIF

TAF1

766

P21675
LRYFSLYEVALVTQG

PTCH2

731

Q9Y6C5
TYSGVFRTQRVDLYQ

PRRC2A

2096

P48634
SVIIIFYCYRVNRQQ

TGFBR2

181

P37173
YIGTTIVVRQVGRYL

RGMA

276

Q96B86
YRQGEVVLTTRDVLY

TECTA

1946

O75443
QIIYGARGTRYQTFV

TRIM5

326

Q9C035
RRYVAQSVQLFILYF

TMEM79

281

Q9BSE2
VARQTLETIRSVGYY

TENM4

1961

Q6N022
LVIGVTLYRRSQSDY

UNC5D

396

Q6UXZ4