Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP:ADP antiporter activity

SLC25A4 SLC25A5 SLC25A6

4.80e-0651583GO:0005471
GeneOntologyMolecularFunctionADP transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

7.66e-05111583GO:0015217
GeneOntologyMolecularFunctionATP transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

1.66e-04141583GO:0005347
GeneOntologyMolecularFunctionbicarbonate channel activity

BEST2 BEST4

1.86e-0431582GO:0160133
GeneOntologyMolecularFunctionmonooxygenase activity

CYP1A1 CYP2D7 CYP2D6 CYP2W1 MOXD1 DEGS2

3.09e-041151586GO:0004497
GeneOntologyMolecularFunctionanandamide 8,9 epoxidase activity

CYP2D7 CYP2D6

3.69e-0441582GO:0062187
GeneOntologyMolecularFunctionanandamide 11,12 epoxidase activity

CYP2D7 CYP2D6

3.69e-0441582GO:0062188
GeneOntologyMolecularFunctionsteroid 21-monooxygenase activity

CYP2D7 CYP2D6

3.69e-0441582GO:0004509
GeneOntologyMolecularFunctionprogesterone 21-hydroxylase activity

CYP2D7 CYP2D6

3.69e-0441582GO:0106309
GeneOntologyMolecularFunctionoxidoreductase activity

DMGDH CYP1A1 RSAD1 AOC1 CYP2D7 CYP2D6 KDM5A BCKDHA HPDL CYP2W1 MOXD1 ALDH16A1 FDXR DEGS2 ALDH1A3 HSD17B4

3.88e-0476615816GO:0016491
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP1A1 CYP2D7 CYP2D6 CYP2W1

6.06e-04491584GO:0016712
GeneOntologyMolecularFunctionTORC2 complex binding

PINK1 NCKAP1L

6.13e-0451582GO:1904841
GeneOntologyMolecularFunctionadenine transmembrane transporter activity

SLC25A4 SLC25A5

6.13e-0451582GO:0015207
GeneOntologyMolecularFunctionoxidative phosphorylation uncoupler activity

SLC25A4 SLC25A5

6.13e-0451582GO:0017077
GeneOntologyMolecularFunctionpurine ribonucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

7.66e-04231583GO:0005346
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP1A1 CYP2D7 CYP2D6 KDM5A CYP2W1 MOXD1 DEGS2

9.10e-041941587GO:0016705
GeneOntologyMolecularFunctionanandamide 14,15 epoxidase activity

CYP2D7 CYP2D6

9.14e-0461582GO:0062189
GeneOntologyMolecularFunctionanandamide epoxidase activity

CYP2D7 CYP2D6

9.14e-0461582GO:0062186
GeneOntologyMolecularFunctionadenine nucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

1.11e-03261583GO:0000295
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP1A1 CYP2D7 CYP2D6

1.24e-03271583GO:0008391
GeneOntologyMolecularFunctionsphingosine N-acyltransferase activity

CERS2 CERS1

1.27e-0371582GO:0050291
GeneOntologyMolecularFunctionpurine nucleotide transmembrane transporter activity

SLC25A4 SLC25A5 SLC25A6

1.53e-03291583GO:0015216
GeneOntologyMolecularFunctionsignal recognition particle binding

RHBDD2 DERL3

1.69e-0381582GO:0005047
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate binding

MAPKAP1 SESTD1 WIPI2

1.86e-03311583GO:0080025
GeneOntologyBiologicalProcessmitochondrial ADP transmembrane transport

SLC25A4 SLC25A5 SLC25A6

3.73e-0651503GO:0140021
GeneOntologyBiologicalProcessautophagy of mitochondrion

ATG9B SLC25A4 SLC25A5 NIPSNAP2 CERS1 WIPI2 PINK1

2.01e-051141507GO:0000422
GeneOntologyBiologicalProcessmitochondrial ATP transmembrane transport

SLC25A4 SLC25A5 SLC25A6

2.06e-0581503GO:1990544
GeneOntologyBiologicalProcessmitochondrion organization

ATG9B HRK SLC25A4 SLC25A5 SLC25A6 NIPSNAP2 TWNK STOX1 TOMM70 ATAD3C PKD1 TIMM29 CERS1 WIPI2 PINK1

2.67e-0558915015GO:0007005
GeneOntologyBiologicalProcesscellular catabolic process

HEXB CYP1A1 ENPP7 ATG9B CYP2D7 CYP2D6 SLC25A4 SLC25A5 TICAM1 NIPSNAP2 BCKDHA CPT1B ITGB4 CYP2W1 PHKG2 GCAT HOGA1 UCHL1 CERS1 HSD17B4 WIPI2 PINK1 HDC

3.73e-05125315023GO:0044248
GeneOntologyBiologicalProcesscatechol-containing compound biosynthetic process

CYP2D7 CYP2D6 MOXD1 HDC

5.54e-05291504GO:0009713
GeneOntologyBiologicalProcesscatecholamine biosynthetic process

CYP2D7 CYP2D6 MOXD1 HDC

5.54e-05291504GO:0042423
GeneOntologyBiologicalProcessADP transport

SLC25A4 SLC25A5 SLC25A6

7.90e-05121503GO:0015866
GeneOntologyBiologicalProcessammonium ion metabolic process

DMGDH CYP2D7 CYP2D6 HDC

8.25e-05321504GO:0097164
GeneOntologyBiologicalProcessamine metabolic process

DMGDH CYP1A1 AOC1 CYP2D7 CYP2D6 MOXD1 HDC

1.06e-041481507GO:0009308
GeneOntologyBiologicalProcessserotonin biosynthetic process from tryptophan

CYP2D7 CYP2D6

1.57e-0431502GO:0006587
GeneOntologyBiologicalProcessnegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

SLC25A4 SLC25A5 SLC25A6

1.61e-04151503GO:1901029
GeneOntologyBiologicalProcessregulation of mitophagy

SLC25A4 SLC25A5 CERS1 PINK1

1.64e-04381504GO:1901524
GeneOntologyBiologicalProcessceramide metabolic process

HEXB B3GALT2 CERS2 ENPP7 DEGS2 CERS1

1.78e-041131506GO:0006672
GeneOntologyBiologicalProcessregulation of mitochondrion organization

HRK SLC25A4 SLC25A5 SLC25A6 STOX1 CERS1 PINK1

1.86e-041621507GO:0010821
GeneOntologyBiologicalProcessceramide biosynthetic process

B3GALT2 CERS2 ENPP7 DEGS2 CERS1

1.92e-04731505GO:0046513
GeneOntologyBiologicalProcesspositive regulation of mitophagy

SLC25A4 SLC25A5 CERS1

1.97e-04161503GO:1901526
GeneOntologyBiologicalProcessmitophagy

SLC25A4 SLC25A5 NIPSNAP2 CERS1 PINK1

2.18e-04751505GO:0000423
GeneOntologyBiologicalProcessTORC2 signaling

MAPKAP1 PINK1 NCKAP1L

2.38e-04171503GO:0038203
GeneOntologyBiologicalProcessregulation of autophagy of mitochondrion

SLC25A4 SLC25A5 CERS1 PINK1

3.18e-04451504GO:1903146
GeneOntologyBiologicalProcesspositive regulation of autophagy of mitochondrion

SLC25A4 SLC25A5 CERS1

3.35e-04191503GO:1903599
GeneOntologyBiologicalProcessaromatic amino acid metabolic process

CYP2D7 CYP2D6 HPDL HDC

3.46e-04461504GO:0009072
GeneOntologyBiologicalProcessbiogenic amine biosynthetic process

CYP2D7 CYP2D6 MOXD1 HDC

3.76e-04471504GO:0042401
GeneOntologyBiologicalProcessmitochondrial membrane organization

SLC25A4 SLC25A5 SLC25A6 TOMM70 TIMM29 PINK1

3.96e-041311506GO:0007006
GeneOntologyBiologicalProcessamine biosynthetic process

CYP2D7 CYP2D6 MOXD1 HDC

4.08e-04481504GO:0009309
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

MAPKAP1 STOX1 SPTBN4 NRXN1 UHMK1 PKD1 BRSK1 MAST3 PINK1

4.23e-043071509GO:0018105
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6 RYR1

1.43e-05191144M47760
PathwayREACTOME_XENOBIOTICS

CYP1A1 CYP2D7 CYP2D6 CYP2W1

4.50e-05251144MM14846
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01006

SLC25A4 SLC25A5 SLC25A6

5.93e-05101143M47694
PathwayKEGG_HISTIDINE_METABOLISM

AOC1 LCMT2 ALDH1A3 HDC

8.24e-05291144M12524
PathwayREACTOME_TRANSPORT_OF_NUCLEOSIDES_AND_FREE_PURINE_AND_PYRIMIDINE_BASES_ACROSS_THE_PLASMA_MEMBRANE

SLC25A4 SLC25A5 SLC25A6

1.07e-04121143M27728
PathwayREACTOME_METABOLISM_OF_LIPIDS

HEXB CERS2 CYP1A1 ENPP7 CYP2D7 CYP2D6 ACSF2 CPT1B FDXR HELZ2 ALB DEGS2 CERS1 HSD17B4 PLEKHA8

1.38e-0462011415MM15193
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.39e-04131143M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.39e-04131143M47751
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_VGCC_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

1.39e-04131143M47703
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

SLC25A4 SLC25A5 SLC25A6

1.76e-04141143M47692
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP1A1 CYP2D7 CYP2D6 CYP2W1 FDXR

1.91e-04661145MM14839
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP1A1 AOC1 CYP2D7 CYP2D6 CYP2W1 FDXR

2.06e-041051146MM14842
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

2.18e-04151143M47691
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

2.67e-04161143M47695
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABBERANT_ATXN2_3_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

3.85e-04181143M47659
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP2D7 CYP2D6 CYP2W1

3.85e-04181143MM14843
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

3.85e-04181143M47761
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

SLC25A4 SLC25A5 SLC25A6

4.54e-04191143M47677
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

5.31e-04201143M47688
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

6.16e-04211143M47689
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

7.09e-04221143M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

7.09e-04221143M47675
PathwayREACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS

CYP1A1 CYP2D7 CYP2D6

7.09e-04221143MM15614
PathwayREACTOME_XENOBIOTICS

CYP1A1 CYP2D6 CYP2W1

8.11e-04231143M5372
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

8.11e-04231143M47666
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

SLC25A4 SLC25A5 SLC25A6

8.11e-04231143M47676
PathwayREACTOME_SPHINGOLIPID_METABOLISM

HEXB CERS2 ENPP7 DEGS2 CERS1

8.90e-04921145MM15086
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

CERS2 DEGS2 CERS1

1.04e-03251143MM15931
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

CERS2 DEGS2 CERS1

1.17e-03261143M39784
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

CERS2 DEGS2 CERS1

1.17e-03261143MM15892
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

CERS2 DEGS2 CERS1

1.31e-03271143MM14646
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

CERS2 DEGS2 CERS1

1.31e-03271143M39863
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMB3 ITGB4 NRXN1 SDC3

1.31e-03591144M27218
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PINK1_TO_INTRINSIC_APOPTOTIC_PATHWAY_N01048

TRAP1 PINK1

1.33e-0371142M47707
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP1A1 AOC1 CYP2D6 CYP2W1 FDXR

1.54e-031041145M738
Pubmed

The human mitochondrial ADP/ATP carriers: kinetic properties and biogenesis of wild-type and mutant proteins in the yeast S. cerevisiae.

SLC25A4 SLC25A5 SLC25A6

9.56e-083160312450408
Pubmed

DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.

SLC25A4 SLC25A5 SLC25A6

9.56e-08316032541251
Pubmed

Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.

SLC25A4 SLC25A5 SLC25A6

9.56e-08316032829183
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

DMGDH CYP1A1 RSAD1 SLC25A4 SLC25A5 SLC25A6 TRMT1 NIPSNAP2 TWNK BCKDHA ACSF2 HPDL TOMM70 TRAP1 GCAT NT5DC2 HOGA1 FDXR TIMM29 PINK1

3.08e-0711361602034800366
Pubmed

Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers.

SLC25A4 SLC25A5 SLC25A6

3.81e-074160333396658
Pubmed

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

SLC25A4 SLC25A5 SLC25A6

1.89e-066160310620603
Pubmed

Polymorphism of metabolic genes and susceptibility to occupational chronic manganism.

CYP1A1 CYP2D7 CYP2D6

1.89e-066160312171760
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MAPKAP1 CDC42BPG SLC25A4 NOL6 RHBDD2 LAMB3 TOMM70 FREM2 ARAP3 AP5B1 ARMC5 TIMM29 HSD17B4 PLXNB1

2.08e-066501601438777146
Pubmed

Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.

SLC25A4 SLC25A5 SLC25A6 NIPSNAP2 BCKDHA CPT1B

2.26e-0682160620833797
Pubmed

Expression of leucine-rich repeat kinase 2 (LRRK2) inhibits the processing of uMtCK to induce cell death in a cell culture model system.

SLC25A4 SLC25A5 SLC25A6

3.30e-067160321370995
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 RHBDF2 HECTD4 TRMT1 LAMB3 TWNK ITGA3 EDC4 ADGRA2 ITGB4 RYR1 ARAP3 IL17RE PKD1 HELZ2 SMURF2 WNK2 TJP3

3.71e-0611051601835748872
Pubmed

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.

SLC25A4 SLC25A5 SLC25A6 YWHAE

4.27e-0624160424725412
Pubmed

TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.

SLC25A4 SLC25A5 SLC25A6

5.26e-068160327641616
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMB3 ITGA3 ITGB4

5.26e-068160323529140
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

USP34 SESTD1 USP24 BCKDHA ANKRD13A MOXD1 HECW2 ALB

6.74e-06212160833853758
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

DMGDH RSAD1 SLC25A4 SLC25A5 NIPSNAP2 TWNK BCKDHA ACSF2 CPT1B TOMM70 TRAP1 ATAD3C GCAT HOGA1 FDXR HSD17B4 PINK1

7.33e-0610471601718614015
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CDC42BPG SLC25A5 LAMB3 MAGEE2 STOX1 CPT1B TEKT5 RYR1 CHRNB4 FREM2 HECW2 ALDH16A1 PKD1 ALB

8.58e-067361601429676528
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

DMGDH SLC25A5 NIPSNAP2 BCKDHA CPT1B YWHAE TOMM70 TRAP1 ATAD3C GCAT HOGA1 FDXR

8.69e-065421601214651853
Pubmed

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

EMC4 SLC25A4 SLC25A5 NIPSNAP2 BCKDHA ACSF2 YWHAE TOMM70 TRAP1 UCHL1 ALDH16A1 FDXR ALB HSD17B4 PINK1

1.12e-058591601531536960
Pubmed

Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75.

SLC25A5 SLC25A6 TOMM70

1.12e-0510160330590033
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

SLC25A4 SLC25A5 NIPSNAP2 BCKDHA ACSF2 CPT1B TOMM70 TRAP1 ATAD3C HSD17B4

1.20e-053821601029222160
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HEXB CERS2 USP34 EMC4 SLC25A4 SLC25A5 CD109 RHBDD2 BCKDHA ACSF2 HPDL YWHAE LCMT2 TRAP1 ANGPTL2 ATAD3C GCAT NT5DC2 FDXR HSD17B4

1.24e-0514511602030550785
Pubmed

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.

SLC25A5 SLC25A6 NIPSNAP2 HNRNPUL1 TRAP1 TIMM29 ALB BRSK1

1.47e-05236160836339263
Pubmed

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

LAMB3 ITGA3 ITGB4

1.53e-0511160310811835
Pubmed

Mitochondrial membrane permeabilization by HIV-1 Vpr.

SLC25A4 SLC25A5 SLC25A6

2.04e-0512160316120388
Pubmed

Risk of renal cell carcinoma and polymorphism in phase I xenobiotic metabolizing CYP1A1 and CYP2D6 enzymes.

CYP1A1 CYP2D6

2.10e-052160222281432
Pubmed

Diagnostic value of integrin alpha3, beta4, and beta5 gene expression levels for the clinical outcome of tongue squamous cell carcinoma.

ITGA3 ITGB4

2.10e-052160218224668
Pubmed

Association of CYP1A1 and CYP2D6 gene polymorphisms with head and neck cancer in Tunisian patients.

CYP1A1 CYP2D6

2.10e-052160224449363
Pubmed

CYP1A1 and CYP2D6 Polymorphisms and Susceptibility to Chronic Myelocytic Leukaemia.

CYP1A1 CYP2D6

2.10e-052160232418524
Pubmed

Histological analyses by matrix-assisted laser desorption/ionization-imaging mass spectrometry reveal differential localization of sphingomyelin molecular species regulated by particular ceramide synthase in mouse brains.

CERS2 CERS1

2.10e-052160226398595
Pubmed

CYP1A1 and CYP2D6 gene polymorphisms in Israeli Jewish women with cervical cancer.

CYP1A1 CYP2D6

2.10e-052160220009880
Pubmed

CYP1A1 and CYP2D6 polymorphism and risk of lung cancer in a North Indian population.

CYP1A1 CYP2D6

2.10e-052160214602525
Pubmed

Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.

CYP2D7 CYP2D6

2.10e-052160225808902
Pubmed

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

CYP2D7 CYP2D6

2.10e-052160211207030
Pubmed

CYP2D6 and CYP1A1 mutations in the Turkish population.

CYP1A1 CYP2D6

2.10e-052160215648054
Pubmed

Tom70 is essential for PINK1 import into mitochondria.

TOMM70 PINK1

2.10e-052160223472196
Pubmed

Changes in the expression of the human adenine nucleotide translocase isoforms condition cellular metabolic/proliferative status.

SLC25A5 SLC25A6

2.10e-052160226842067
Pubmed

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore.

SLC25A4 SLC25A5

2.10e-052160214749836
Pubmed

Altered gene expression in cells from patients with lysosomal storage disorders suggests impairment of the ubiquitin pathway.

HEXB UCHL1

2.10e-052160216888648
Pubmed

Associations and interaction effects of maternal smoking and genetic polymorphisms of cytochrome P450 genes with risk of congenital heart disease in offspring: A case-control study.

CYP1A1 CYP2D6

2.10e-052160234115022
Pubmed

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

CYP2D7 CYP2D6

2.10e-05216023123997
Pubmed

Ischemia-modified albumin in pregnancy.

PAPPA ALB

2.10e-052160223891063
Pubmed

Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development.

ITGA3 ITGB4

2.10e-052160211784011
Pubmed

Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency.

CERS2 CERS1

2.10e-052160227162368
Pubmed

A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant progressive external ophthalmoplegia patients with mitochondrial DNA with multiple deletions.

SLC25A4 SLC25A6

2.10e-052160212112115
Pubmed

Role of adenine nucleotide translocator 1 in mtDNA maintenance.

SLC25A4 SLC25A6

2.10e-052160210926541
Pubmed

Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.

CYP2D7 CYP2D6

2.10e-052160211032406
Pubmed

Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure.

CERS2 PINK1

2.10e-052160229196503
Pubmed

ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma.

ITGA3 ITGB4

2.10e-052160224006899
Pubmed

Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.

FRAT1 DNTT

2.10e-05216029034327
Pubmed

Meta-analyses of the effect of CYP1A1 and CYP2D6 polymorphisms on the risk of head and neck squamous cell carcinoma.

CYP1A1 CYP2D6

2.10e-052160225138301
Pubmed

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1.

TRAP1 PINK1

2.10e-052160217579517
Pubmed

Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.

SLC25A4 SLC25A5

2.10e-052160227048932
Pubmed

Apoptotic and anti-proliferative effects of all-trans retinoic acid. Adenine nucleotide translocase sensitizes HeLa cells to all-trans retinoic acid.

SLC25A4 SLC25A6

2.10e-052160216556444
Pubmed

cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.

SLC25A4 SLC25A6

2.10e-05216022823266
Pubmed

TRAP1 rescues PINK1 loss-of-function phenotypes.

TRAP1 PINK1

2.10e-052160223525905
Pubmed

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

CYP2D7 CYP2D6

2.10e-052160219594327
Pubmed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.

CYP2D7 CYP2D6

2.10e-052160226297049
Pubmed

Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells.

BEST2 BEST4

2.10e-052160224223998
Pubmed

Expression and sequence analysis of the mouse adenine nucleotide translocase 1 and 2 genes.

SLC25A4 SLC25A5

2.10e-052160210974536
Pubmed

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.

CYP2D7 CYP2D6

2.10e-052160215051713
Pubmed

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis.

PKD1 PAPPA

2.10e-052160231990681
Pubmed

The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria.

TOMM70 PINK1

2.10e-052160235391620
Pubmed

A novel missense adenine nucleotide translocator-1 gene mutation in a Greek adPEO family.

SLC25A4 SLC25A6

2.10e-052160211756613
Pubmed

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.

SLC25A4 SLC25A5 SLC25A6 TRMT1 NIPSNAP2 BCKDHA ACSF2 NT5DC2 HOGA1 TIMM29

2.34e-054131601027499296
Pubmed

Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.

HEXB YWHAE TRAP1 KHK

2.53e-0537160419865483
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

DMGDH RSAD1 SLC25A4 NIPSNAP2 TWNK BCKDHA ACSF2 CPT1B TOMM70 TRAP1 GCAT HOGA1 FDXR HSD17B4 PINK1

2.67e-059261601520877624
Pubmed

The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration.

ITGA3 ITGB4 YWHAE

3.35e-0514160312919677
Pubmed

Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function.

SLC25A5 YWHAE UCHL1

4.17e-0515160319725078
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

SLC25A5 SLC25A6 MYH7B USP24 ACSF2 YWHAE TOMM70 TRAP1 ATAD3C UCHL1 ALDH16A1 FDXR HSD17B4 DYNC1I2

5.91e-058781601437223481
Pubmed

Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson's disease among Taiwanese.

USP24 UCHL1

6.29e-053160220302855
Pubmed

Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy.

OTOP3 FDXR

6.29e-053160229040572
Pubmed

Mutation of the linker region of the polymerase gamma-1 (POLG1) gene associated with progressive external ophthalmoplegia and Parkinsonism.

SLC25A4 TWNK

6.29e-053160217420318
Pubmed

CYP2A6, CYP1A1, and CYP2D6 polymorphisms in lung cancer patients from central south China.

CYP1A1 CYP2D6

6.29e-053160223471717
Pubmed

MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway.

LAMB3 ITGB4

6.29e-053160238375821
Pubmed

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system.

TOMM70 PINK1

6.29e-053160238848361
Pubmed

Bestrophin Cl- channels are highly permeable to HCO3-.

BEST2 BEST4

6.29e-053160218400985
Pubmed

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.

CYP2D7 CYP2D6

6.29e-05316022574001
Pubmed

Mutations of ANT1, Twinkle, and POLG1 in sporadic progressive external ophthalmoplegia (PEO).

SLC25A4 TWNK

6.29e-053160212707443
Pubmed

Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration.

SLC25A4 TWNK

6.29e-053160220181062
Pubmed

Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells.

ALB PINK1

6.29e-053160229494565
Pubmed

Poor metabolizers at the cytochrome P450 2D6 and 2C19 loci are at increased risk of developing adult acute leukaemia.

CYP1A1 CYP2D6

6.29e-053160211037802
Pubmed

Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively.

SLC25A4 SLC25A5

6.29e-053160216831128
Pubmed

Identification of the primary gene defect at the cytochrome P450 CYP2D locus.

CYP2D7 CYP2D6

6.29e-05316021978251
Pubmed

ANT1, Twinkle, POLG, and TP: new genes open our eyes to ophthalmoplegia.

SLC25A4 TWNK

6.29e-053160211756592
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

ITGA3 ITGB4 SPTBN4

7.41e-0518160312119179
Pubmed

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.

SLC25A4 SLC25A5 NIPSNAP2 ANKRD13A PINK1

9.77e-0599160529676259
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

MIIP EMC4 SLC25A5 MYO9A TRMT1 ACSF2 ITGB4 TRAP1 ALDH16A1 ARMC5 PKD1 HSD17B4 DYNC1I2 BRWD1

1.02e-049251601428986522
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

LAMB3 ITGB4 FREM2

1.20e-0421160327856617
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SLC25A4 SLC25A5 SLC25A6 KDM5A MYH7B NOL6 NIPSNAP2 TWNK TRIM43 STOX1 SPTBN4 CCDC27 TRAP1 ATAD3C NRXN1 HSD17B4 SMURF2 DYNC1I2

1.22e-0414421601835575683
Pubmed

DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.

SLC25A5 SLC25A6 HNRNPUL1 YWHAE TIGD6 CCDC27 ALB

1.24e-04238160735864588
Pubmed

Gene polymorphisms in detoxification enzymes as susceptibility factor for head and neck cancer?

CYP1A1 CYP2D6

1.25e-044160212748560
Pubmed

Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility.

CYP1A1 CYP2D6

1.25e-044160218414197
Pubmed

The interaction between cell adhesion molecule L1, matrix metalloproteinase 14, and adenine nucleotide translocator at the plasma membrane regulates L1-mediated neurite outgrowth of murine cerebellar neurons.

SLC25A4 SLC25A5

1.25e-044160222423112
Pubmed

[The relationship between genetic polymorphism of metabolizing enzymes and the genetic susceptibility to lung cancer].

CYP1A1 CYP2D6

1.25e-044160215769360
Pubmed

Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes.

ITGA3 ITGB4

1.25e-044160216707493
Pubmed

Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD.

SLC25A4 SLC25A5

1.25e-044160231489369
Pubmed

Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias.

CYP1A1 CYP2D6

1.25e-044160216493615
Pubmed

Novel Twinkle (PEO1) gene mutations in mendelian progressive external ophthalmoplegia.

SLC25A4 TWNK

1.25e-044160218575922
Pubmed

Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family.

BEST2 BEST4

1.25e-044160212032738
CytobandEnsembl 112 genes in cytogenetic band chr19p13

AMH CPAMD8 ADAT3 BEST2 TICAM1 AZU1 TRMT1 NIBAN3 TIMM29 CERS1 MAST3 TJP3

2.56e-0579716012chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr22q13

CYP2D7 CYP2D6 RIBC2 CPT1B PKDREJ GCAT GRAP2

1.70e-043301607chr22q13
Cytoband17q21.33

RSAD1 ITGA3 ACSF2

4.02e-0441160317q21.33
CytobandEnsembl 112 genes in cytogenetic band chr10q24

FRAT1 FBXW4 TWNK HOGA1 DNTT

5.49e-041891605chr10q24
Cytoband1p34.1

HPDL BTBD19 CCDC17

1.06e-035716031p34.1
CytobandYp11.3

SLC25A6 SHOX

1.40e-03161602Yp11.3
Cytoband19p13.3

AMH ADAT3 TICAM1 AZU1 TJP3

1.51e-03237160519p13.3
GeneFamilyRhomboid family

RHBDF2 RHBDD2 DERL3

6.24e-05141033926
GeneFamilyBestrophins

BEST2 BEST4

1.91e-0441032866
GeneFamilyCERS class homeoboxes

CERS2 CERS1

4.75e-0461032530
GeneFamilyCytochrome P450 family 2

CYP2D7 CYP2D6 CYP2W1

1.03e-033510331001
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

CPAMD8 CD109

1.13e-03910321234
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RHBDD2 RAB44 TTLL7 CRYGD SIGLEC6 GRAP2 HSD17B4 HDC

6.15e-0719816082e6630eab77b12a6059682ab5ba465f38e469102
ToppCellBiopsy_Other_PF-Epithelial-KRT5-/KRT17+|Biopsy_Other_PF / Sample group, Lineage and Cell type

CDC42BPG RHOD LAMB3 ITGA3 ITGB4 PAPPA ALDH1A3 PLXNB1

6.63e-072001608077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCell343B-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TTLL7 MOXD1 NT5DC2 UCHL1 DERL3 IGLL1 BRSK1

2.20e-061641607cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell343B-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TTLL7 MOXD1 NT5DC2 UCHL1 DERL3 IGLL1 BRSK1

2.20e-061641607e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

NPTX2 AZU1 RAB44 CRYGD IGLL1 PLXNB1 DNTT

2.29e-0616516077b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

NPHP1 AZU1 CRYGD GCAT UCHL1 ROBO1 IGLL1

2.38e-06166160720f248d95c86eb52a1efe9abe73123fbe4206caf
ToppCellwk_15-18-Hematologic-Myeloid-Mast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RASGRP4 AOC1 RAB44 CRYGD SIGLEC6 GRAP2 HDC

3.01e-061721607a7146c255031207e64682ef767884b11c96e0d59
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_12|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RIBC2 CD109 PAQR4 TRIM43 ACSF2 NT5DC2 SIGLEC6

3.13e-061731607a55f310c533432e9e26e400026a5b47245152976
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_12|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIBC2 CD109 PAQR4 TRIM43 ACSF2 NT5DC2 SIGLEC6

3.13e-0617316079c7386bf0a899882c733f0b4921a96afde032a7d
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

NPTX2 AZU1 RAB44 KIF15 NT5DC2 IGLL1 DNTT

3.25e-061741607029394e107bf7ad58056d2216070aa2e964fff12
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CYP1A1 RHOD LAMB3 PKDREJ ITGB4 DERL3 ALDH1A3

3.78e-0617816079a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP1A1 RHOD LAMB3 PKDREJ ITGB4 DERL3 ALDH1A3

3.78e-061781607b413a634283550fa224db7d0d05956e3f64694a1
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP1A1 RHOD LAMB3 PKDREJ ITGB4 DERL3 ALDH1A3

3.78e-06178160749a2271718637522f74334068d252963ee13b1ce
ToppCellnormal-na-Lymphocytic_B-plasmablast-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

SLC25A4 C1orf167 MOXD1 NT5DC2 UCHL1 DERL3 IGLL1

3.78e-06178160740a280c1e35963dd45d1809a3e85b568344dd1f5
ToppCellnormal-na-Lymphocytic_B-plasmablast|normal / PBMC cell types (v2) per disease, treatment status, and sex

SLC25A4 C1orf167 MOXD1 NT5DC2 UCHL1 DERL3 IGLL1

3.78e-0617816074fe87c713770173336177e3488f7b4a3be54f71b
ToppCellBAL-Severe-Epithelial-Epithelial-undefined_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP1A1 RHOD LAMB3 PKDREJ ITGB4 DERL3 ALDH1A3

3.78e-06178160719b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 LAMB3 CYP2W1 MOXD1 ANGPTL2 IL17RE HPN

4.22e-061811607a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 LAMB3 CYP2W1 MOXD1 ANGPTL2 IL17RE HPN

4.22e-061811607504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD109 LAMB3 CYP2W1 MOXD1 ANGPTL2 IL17RE HPN

4.22e-061811607a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-0618216076497eeafb2b137e70261ec0314782831892a940d
ToppCellControl-Hematopoietic_SC-HSPC|Control / Disease group, lineage and cell class

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-06182160714e347c0e6444410f1948851407bb18c706569f4
ToppCellControl-Hematopoietic_SC|Control / Disease group, lineage and cell class

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-06182160743243c6bae2ac7fa3fd1f193a17f61ee4d938ea9
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-061821607d0ebf2f0d5370458ab81485a0017c311077133d5
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-061821607bd1626261803324084fafca2f6665b50854e7fae
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-0618216072a6d1246bfb5899a0861c7f2f8fb9b43b0df8acc
ToppCellPBMC-Control-Hematopoietic-HSPC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-061821607918286422b3eab32d962b49aa07b1b9512e51d9d
ToppCellPBMC-Control-Hematopoietic-HSPC-HSPC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NPTX2 CD109 CRYGD UCHL1 IGLL1 HDC DNTT

4.37e-0618216070d9b8c900da8cbae9cde72aecd4026b1ac2bbd67
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NOL6 MAMDC4 CYP2W1 FREM2 HPN CCDC183 WNK2

4.87e-061851607636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellmild_COVID-19-Plasmablast|mild_COVID-19 / disease group, cell group and cell class (v2)

ENPP7 SLC25A4 HPDL CBY3 NT5DC2 UCHL1 DERL3

5.04e-061861607a639d2183b85b1be6e6da2b2e112aec5149d5bcd
ToppCellmild_COVID-19-Plasmablast|World / disease group, cell group and cell class (v2)

ENPP7 SLC25A4 HPDL KIF15 NT5DC2 UCHL1 DERL3

5.41e-0618816079a5ba6abdc307402301dae25db2a5f3e0d576417
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT2 LAMB3 ITGB4 NRXN1 IL17RE HPN PLXNB1

5.60e-061891607783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellBac-SEP-Lymphocyte-B-Plasmablast|Bac-SEP / Disease, Lineage and Cell Type

SLC25A4 KCNK12 KIF15 NT5DC2 UCHL1 DERL3 IGLL1

5.60e-0618916076339b6d1056e07cefb0e1b2a0e479913c5783c8a
ToppCell3'-Distal_airway-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIIP RASGRP4 RHBDD2 RAB44 SIGLEC6 GRAP2 HDC

5.60e-06189160796566f84c796d5b2e31f64090555f2b258f0c9f2
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIIP RASGRP4 RHBDD2 RAB44 SIGLEC6 GRAP2 HDC

5.60e-061891607b59cc66f7bb9b72895b775fbcf1ec1dc08610969
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIIP RASGRP4 RHBDD2 RAB44 SIGLEC6 GRAP2 HDC

5.60e-0618916071893765b1e3b306f1e133101c28403070a70c3c8
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT2 LAMB3 ITGB4 NRXN1 IL17RE HPN PLXNB1

5.60e-06189160788b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIIP RASGRP4 RHBDD2 RAB44 SIGLEC6 GRAP2 HDC

5.60e-06189160719b639bc6b35fe1d1079f60c8138aa946a95f3bf
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GALT2 LAMB3 ITGB4 NRXN1 IL17RE HPN PLXNB1

5.80e-06190160747e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GALT2 LAMB3 ITGB4 NRXN1 IL17RE HPN PLXNB1

5.80e-061901607261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 LAMB3 MAMDC4 CYP2W1 HPN TJP3 SLC22A31

6.43e-061931607930df79b0600f43617052313294be33bcf5631f0
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNRNPUL1 NIBAN3 KIF15 NRXN1 UCHL1 IGLL1 DNTT

6.65e-0619416078ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP7 AOC1 LAMB3 MAMDC4 CYP2W1 HPN KHK

6.65e-061941607fcbf9c4f3801ab1a34fcd62c752fabc97fc7bde1
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RASGRP4 RHBDD2 RAB44 SIGLEC6 GRAP2 HSD17B4 HDC

6.87e-061951607fbedb9978ded857fd35c2a8664f7579f42edaa36
ToppCelldistal-Hematologic-Plasma-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NPTX2 KCNK12 NYX MOXD1 DERL3 IGLL1 BRSK1

6.87e-0619516074280a5bc5ed9bb12e278b182e0be6cb88fa83d83
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AOC1 LAMB3 MAMDC4 CYP2W1 HPN DEGS2 TJP3

6.87e-0619516079c24ebce2e3e00b8b692c62a22a53b7d59f0eabb
ToppCelldistal-Hematologic-Plasma-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KCNK12 TECTA TTLL7 MOXD1 DERL3 IGLL1 BRSK1

7.11e-0619616078201aded3c7109fae5e6ca12bac2076acc7bf070
ToppCelldistal-1-Hematologic-Plasma|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KCNK12 TECTA TTLL7 MOXD1 DERL3 IGLL1 BRSK1

7.35e-061971607f5499bfa9dbc111f12563b7006bc45c2423ad0cd
ToppCellmild-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC25A4 CBY3 MOXD1 ATAD3C NT5DC2 UCHL1 DERL3

7.35e-06197160721085d5e27b5a23a241a933058bb89f8a1fcf198
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AOC1 ANKRD13A FREM2 SDC3 PAPPA DEGS2 ALDH1A3

7.59e-0619816070d9d401190792fd61434f1b82548253187d805f0
ToppCellMS-Multiple_Sclerosis-Lymphocyte-B-Plasmablast|Multiple_Sclerosis / Disease, condition lineage and cell class

SLC25A4 HPDL MOXD1 NT5DC2 UCHL1 DERL3 IGLL1

7.59e-061981607c30b71b998acde080adb90a2016a165c5ed17a81
ToppCellSepsis-Bac-SEP-Lymphocyte-B-Plasmablast|Bac-SEP / Disease, condition lineage and cell class

SLC25A4 KCNK12 KIF15 NT5DC2 UCHL1 DERL3 IGLL1

7.59e-061981607614055c11d1dd2f3f2b8783ec35a8f4570cad161
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RASGRP4 RAB44 TTLL7 SIGLEC6 GRAP2 HSD17B4 HDC

7.59e-061981607a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP7 AOC1 LAMB3 MAMDC4 CYP2W1 HPN KHK

8.11e-06200160773bfdf068a8ecbefc1e6afe9686df73658ee042f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

TEKT5 ATAD3C IL17RE CCDC183 TJP3 SLC22A31

8.70e-061331606b6d0fe227faec9c119498b5b9cec2a755ec29c00
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

AOC1 TEKT5 CYP2W1 NRXN1 WNK2 DNTT

1.66e-05149160681c813588bb5efb7b31141a75d387210dcb76094
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-stem_cells_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

NPHP1 AMH ATG9B NPTX2 TIGD6 IL17RE

1.86e-051521606375c9ef88c7703a002e868645a722c35e046ef1e
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RASGRP4 CD109 RAB44 TTLL7 SIGLEC6 HDC

1.86e-05152160632634195048858ae84605c61e43c542d90f7cab5
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RASGRP4 CD109 RAB44 TTLL7 SIGLEC6 HDC

1.86e-0515216060eb185b2404f015efff1bd140e0c502d714720fb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOC1 HRK LAMB3 RAB44 PAPPA ALDH1A3

2.08e-05155160629c4e9947bb4f7e257ed5c3bcf21bd67f88d473f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

CPAMD8 XKR8 TEKT5 IL17RE TJP3 SLC22A31

2.08e-05155160657259549d7ad97d9f628b821417be5ddac7dbff7
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

ENPP7 AOC1 LAMB3 CYP2W1 IL17RE KHK

2.15e-051561606f9eb18a0f00de211fab36d7d88fcf08276d53dcc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 NPTX2 OTOP3 TEKT5 ITGB4 NRXN1

2.66e-051621606d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 NPTX2 OTOP3 TEKT5 ITGB4 NRXN1

2.66e-0516216065bbd7130d4dad9035e73a439dda568195c136f31
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 NPTX2 OTOP3 TEKT5 ITGB4 NRXN1

2.66e-051621606eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 NPTX2 OTOP3 TEKT5 ITGB4 NRXN1

2.66e-051621606e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellHealthy_Control-Lymphoid-Plasma|Healthy_Control / Condition, Lineage, Cell class and cell subclass

KCNK12 MOXD1 NT5DC2 DERL3 GRAP2 BTBD19

2.76e-0516316062913ccdd4613472cd82077d4993e1d9f8b223398
ToppCellHealthy_Control-Lymphoid-Plasma-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

KCNK12 MOXD1 NT5DC2 DERL3 GRAP2 BTBD19

2.76e-051631606b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCell3'_v3-Lung-Lymphocytic_B_plasma-Plasma_cells|Lung / Manually curated celltypes from each tissue

TTLL7 CBY3 MOXD1 DERL3 MYEOV SLC22A31

2.85e-0516416063b6a32ba53d05f6818fe950ac426f489383b645a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG9B KCNK12 TEKT5 NIBAN3 HPDL RYR1

2.95e-0516516061b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

RASGRP4 KCNK12 RAB44 NT5DC2 SIGLEC6 HDC

2.95e-0516516065fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

RASGRP4 KCNK12 RAB44 NT5DC2 SIGLEC6 HDC

2.95e-05165160693d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CDC42BPG AOC1 PAQR4 STOX1 MYEOV BRSK1

2.95e-05165160634fd00be2b28716c871ad9fb356de84a299a0c01
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG9B KCNK12 TEKT5 NIBAN3 HPDL RYR1

2.95e-051651606b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SLC25A4 HPDL ATAD3C UCHL1 DERL3 ROBO1

3.06e-0516616060cc3b9681bc000a1b00d3b60f79f16eea1c2e2e1
ToppCellICU-SEP-Lymphocyte-B-Plasmablast|ICU-SEP / Disease, Lineage and Cell Type

SLC25A4 MOXD1 NT5DC2 UCHL1 DERL3 WNK2

3.06e-05166160698ce43e14133418f676f1c88c001add9e28259a7
ToppCellBAL-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DMGDH HRK KCNK12 MOXD1 KIF15 DERL3

3.38e-0516916069ab34f602d46ce87283d243b81621e8806504f43
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DMGDH HRK KCNK12 MOXD1 KIF15 DERL3

3.38e-05169160689fbafdb4628ce7a90c50398870e0f8ee90cfd91
ToppCellBAL-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMGDH HRK KCNK12 MOXD1 KIF15 DERL3

3.38e-05169160675d367eb35768d3063096e8866cea649dac3b1bd
ToppCell3'_v3-blood-Hematopoietic_progenitors-HSC-MPP|blood / Manually curated celltypes from each tissue

AZU1 CRYGD SCML2 NRXN1 UCHL1 IGLL1

3.49e-0517016061443d7fccc81088dd42dcbb9361e269872542274
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPTX2 NIBAN3 DIPK2A SCML2 DERL3 CCDC183

3.49e-051701606b49f7c8a27078de2137ed04f74cfee30729cfa5e
ToppCellIonocyte|World / Class top

HEXB TEKT5 MOXD1 NRXN1 PAPPA ALDH1A3

3.49e-051701606d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell3'_v3-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

NPTX2 CPT1B TTLL7 CRYGD GRAP2 HDC

3.49e-0517016064dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue|TCGA-Stomach / Sample_Type by Project: Shred V9

ENPP7 FAM180B SLC25A4 OTOP3 NRXN1 PINK1

3.61e-0517116060f8d038858a4618b4348becc26a618d43b10d9d6
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 NPTX2 AOC1 RIBC2 GAS2L2 PLXNB1

3.61e-0517116061854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCellTCGA-Stomach-Solid_Tissue_Normal|TCGA-Stomach / Sample_Type by Project: Shred V9

ENPP7 FAM180B SLC25A4 OTOP3 NRXN1 PINK1

3.61e-051711606791d37fe94ff2820fb409bbd38b31799df700ba1
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue|TCGA-Stomach / Sample_Type by Project: Shred V9

ENPP7 FAM180B SLC25A4 OTOP3 NRXN1 PINK1

3.61e-0517116060bf36930bd7fc63691f48a15db93deb1dd937c10
ToppCellControl-B_cell-Plasmablast|Control / Disease group,lineage and cell class (2021.01.30)

DMGDH HRK KCNK12 MOXD1 KIF15 DERL3

3.61e-051711606c09afc4b111b2b5acca75177554f6364ee02d37c
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 FAM180B ADAT3 RHBDF2 NIBAN3 DERL3

3.73e-051721606d40a8bd61114b49a5837c836136a13c37c8f7de0
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 RAB44 CRYGD SIGLEC6 GRAP2 HDC

3.73e-0517216062ab720a4c96073339a1f8b95ec7699682df98acf
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid|bone_marrow / Manually curated celltypes from each tissue

AZU1 RAB44 CRYGD KIF15 NT5DC2 IGLL1

3.85e-0517316065645a3b1e805c71d5d65fc8e4edc4e13208063fc
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

NPTX2 AZU1 CRYGD GCAT IGLL1 DNTT

3.98e-0517416066d9bdf4d28ff8ebb66ffd1ccdd6a4fe9440a83f3
ToppCellMultiple_Sclerosis-Lymphocyte-B-Plasmablast|Multiple_Sclerosis / Disease, Lineage and Cell Type

SLC25A4 MOXD1 NT5DC2 UCHL1 DERL3 IGLL1

3.98e-051741606e8d2aa9505817aac3fe068080774d19458f07b01
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASGRP4 RAB44 CRYGD SIGLEC6 GRAP2 HDC

3.98e-05174160636080fa12497faa752ff07ae52cd3864053eafef
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC25A4 C1orf167 MOXD1 ATAD3C NT5DC2 DERL3

3.98e-051741606bdbaf805a94b2f5a0065933dab6bf84e3cabd525
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC25A4 MOXD1 NT5DC2 UCHL1 DERL3 WNK2

4.24e-051761606dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCellControl-Lymphoid-pDC|Control / Condition, Lineage and Cell class

NPTX2 STOX1 NIBAN3 DERL3 ALDH1A3 CCDC183

4.24e-0517616065de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-HSC-MPP|lymph-node_spleen / Manually curated celltypes from each tissue

AZU1 RAB44 KIF15 GCAT UCHL1 IGLL1

4.24e-051761606de67ed15a50d2515ba6d152c1011a3367f77aedd
ToppCellVE-plasma|VE / Condition, Cell_class and T cell subcluster

C1orf167 MOXD1 NT5DC2 UCHL1 DERL3 WNK2

4.37e-0517716060c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDF2 HRK KCNK12 NIBAN3 IGLL1 NCKAP1L

4.37e-051771606ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCellVE-plasma-|VE / Condition, Cell_class and T cell subcluster

C1orf167 MOXD1 NT5DC2 UCHL1 DERL3 WNK2

4.37e-0517716063a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
DrugClodronate

SLC25A4 SLC25A5 SLC25A6

3.34e-0731593DB00720
DrugAC1L4X2K

SLC25A4 SLC25A5 SLC25A6 ALB

4.65e-07101594CID000193824
Drug16 alpha-hydroxytestosterone

CYP1A1 CYP2D7 CYP2D6 FDXR

1.09e-06121594CID000065545
Drugdehydroabietylamine

SLC25A4 SLC25A5 SLC25A6

1.33e-0641593ctd:C000600819
Drugoxosparteine

AOC1 CYP2D7 CYP2D6

3.31e-0651593CID000097492
Drugmono-(2-ethylhexyl)phthalate

B3GALT2 CYP1A1 AMH RHOD CD109 ITGA3 ITGB4 RYR1 SPTBN4 CCDC27 HECW2 DERL3 FDXR BRSK1 HSD17B4 LY75 WNK2

3.79e-0665815917ctd:C016599
Drugoleoylcarnitine

SLC25A4 SLC25A5 SLC25A6 CPT1B

3.90e-06161594CID006441392
Drugbeta-hydroxypalmitoyl-CoA

SLC25A4 SLC25A5 SLC25A6 HSD17B4

5.08e-06171594CID000440600
Drugchlorpheniramine

CYP2D7 CYP2D6 HPDL ALB HDC

5.67e-06371595CID000002725
Drugclosantel

SLC25A4 SLC25A5 SLC25A6

1.15e-0571593ctd:C023342
Drugdiclofenac

CYP1A1 CYP2D7 CYP2D6 SLC25A4 SLC25A5 SLC25A6 USP24 CYP2W1 ALB

1.69e-052091599CID000003032
DrugZ H-H

AOC1 CYP2D7 CYP2D6

1.82e-0581593CID000004657
DrugAC1L1AH5

CYP1A1 SLC25A4 SLC25A5 SLC25A6 CPT1B GCAT UHMK1 ALB HSD17B4

2.11e-052151599CID000000986
Drugtyramine

DMGDH AOC1 CYP2D7 CYP2D6 MOXD1 UHMK1 HDC

3.65e-051301597CID000005610
Drugbenzaldehyde oxime

AOC1 CYP2D7 CYP2D6

3.87e-05101593CID000012143
Drugcupreidine

CYP2D7 CYP2D6

4.85e-0521592CID000051196
DrugMK785

ALB HDC

4.85e-0521592CID000192909
Drug3-methoxyphenethylamine

CYP2D7 CYP2D6

4.85e-0521592CID000074866
Drug2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole

CYP1A1 CYP2W1

4.85e-0521592ctd:C507816
Drug8-hydroxycarteolol

CYP1A1 CYP2D7 CYP2D6

5.29e-05111593CID000124688
Diseasehypertrophic cardiomyopathy (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6 MYH7B PKD1

3.65e-07291525DOID:11984 (implicated_via_orthology)
Diseaseautosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6

5.34e-0741523DOID:0111517 (implicated_via_orthology)
DiseaseJunctional Epidermolysis Bullosa

LAMB3 ITGA3 ITGB4

2.65e-0661523C0079301
Diseasejunctional epidermolysis bullosa (is_implicated_in)

LAMB3 ITGA3 ITGB4

4.62e-0671523DOID:3209 (is_implicated_in)
DiseaseOccupational Diseases

CYP1A1 CYP2D6 ALB

2.15e-05111523C0028797
Diseasemitochondrial metabolism disease (implicated_via_orthology)

SLC25A4 SLC25A5 SLC25A6 TOMM70

3.13e-05351524DOID:700 (implicated_via_orthology)
Diseasechronic progressive external ophthalmoplegia (is_implicated_in)

SLC25A4 TWNK

7.88e-0531522DOID:12558 (is_implicated_in)
Diseasefibulin-1 measurement

RIBC2 NT5DC2

7.88e-0531522EFO_0802550
DiseaseHerlitz Disease

LAMB3 ITGB4

1.57e-0441522C0079683
Diseasesolanidine measurement

CYP2D7 CYP2D6

1.57e-0441522EFO_0800966
DiseaseEpidermolysis Bullosa Progressiva

LAMB3 ITGB4

1.57e-0441522C0079297
DiseaseHepatomegaly

CYP1A1 CRYGD ALB HDC

1.75e-04541524C0019209
DiseaseAdult junctional epidermolysis bullosa (disorder)

LAMB3 ITGB4

2.61e-0451522C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

LAMB3 ITGB4

2.61e-0451522C2608084
DiseasePerrault syndrome (is_implicated_in)

TWNK HSD17B4

2.61e-0451522DOID:0050857 (is_implicated_in)
DiseaseProgressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1

SLC25A4 TWNK

2.61e-0451522C1834846
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

LAMB3 ITGB4

2.61e-0451522DOID:0060738 (implicated_via_orthology)
DiseasePerrault syndrome

TWNK HSD17B4

3.90e-0461522cv:C0685838
Diseaseoral cavity cancer (is_implicated_in)

CYP1A1 CHRNB4

3.90e-0461522DOID:8618 (is_implicated_in)
DiseaseGonadal dysgenesis XX type deafness

TWNK HSD17B4

5.44e-0471522C0685838
Diseaseplasma betaine measurement

DMGDH KDM5A LY75

7.13e-04341523EFO_0007787
Diseaseneuroimaging measurement, brain volume measurement

USP34 HRK FRAT1 ROBO1 PAPPA MYEOV WNK2

7.31e-042861527EFO_0004346, EFO_0006930
DiseaseHOYERAAL-HREIDARSSON SYNDROME

DCLRE1B TINF2

1.15e-03101522C1846142
DiseaseKunitz-type protease inhibitor 2 measurement

RASGRP4 RYR1

1.15e-03101522EFO_0008200
DiseaseMalignant neoplasm of breast

CYP1A1 ADAT3 CYP2D6 RIBC2 TICAM1 CD109 TECTA PKDREJ MAMDC4 ARAP3 ROBO1 PLEKHA8 PLXNB1 NLRP8

1.36e-03107415214C0006142
Diseaseurate measurement

CERS2 CYP1A1 USP34 CDC42BPG MYO9A HECTD4 TRAP1 NRXN1 AP5B1 ALDH16A1 CCDC17 MAST3

2.38e-0389515212EFO_0004531
Diseaseeosinophil measurement

HEXB USP34 AZU1 TIMM29

2.40e-031081524EFO_0803540
Diseaseankylosing spondylitis (is_implicated_in)

CYP1A1 KDM5A

4.26e-03191522DOID:7147 (is_implicated_in)
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

USP24 NRXN1

4.26e-03191522OBA_2045199

Protein segments in the cluster

PeptideGeneStartEntry
DFWLRSSGRFRQDVQ

CHRNB4

411

P30926
VWFTNLAAQARRDGR

BEST4

186

Q8NFU0
NVIGARRASWRIISS

YWHAE

51

P62258
ASVGRLQWRRVSAQE

MAMDC4

506

Q6UXC1
VWAARRAAARGLRAV

ADAT3

181

Q96EY9
VWFSNLAAQARREGR

BEST2

186

Q8NFU1
GVLSFWRGNLANVIR

SLC25A6

66

P12236
LGLFDQDQRVLSGRW

CCDC17

496

Q96LX7
GLRRRALGAVFATWR

C1orf167

1051

Q5SNV9
GERAFKAWAVARLSQ

ALB

231

P02768
VLGNDRANRFWAGTL

ARAP3

561

Q8WWN8
RQWQLFGTQASRAVR

CCDC85B

96

Q15834
LSARRLRAWGARVQA

ALDH16A1

626

Q8IZ83
ERVANNRGDFRWPRT

ADGRA2

356

Q96PE1
RAWGLRFFRSPQQVL

FDXR

301

P22570
EAAQVAFQRGSPWRR

ALDH1A3

76

P47895
AFQRGSPWRRLDALS

ALDH1A3

81

P47895
GVLSFWRGNLANVIR

SLC25A5

66

P05141
FSSGARWRAARQFTV

CYP2W1

116

Q8TAV3
ERAQGGSFRSLRSWL

ARMC5

446

Q96C12
RSLLQRWGASFRRGA

AIDA

6

Q96BJ3
ALGAWRGRERAQAAT

ADARB2-AS1

16

A8MUL3
LGARAALSRSWQEAR

ACSF2

21

Q96CM8
WQEARLQGVRFLSSR

ACSF2

31

Q96CM8
RRLDGSVNFFRNWET

ANGPTL2

321

Q9UKU9
GVASGQRRSWLIIQR

AOC1

191

P19801
VWSRRSPRVRVNFFG

DERL3

131

Q96Q80
RLSNQAFVFRGGRWT

CBY3

126

A6NI87
IAVDFWSLRRAGTAR

DCLRE1B

11

Q9H816
QSGLSGRQVERWFRR

CERS2

106

Q96G23
WRGTQDLFLARRGSD

CCDC27

166

Q2M243
WARAIRFRQDGNEAV

NIPSNAP2

206

O75323
GRLDAARGRVSWQVE

RAB44

321

Q7Z6P3
DSGPVWAARRRLAQN

CYP1A1

126

P04798
FWRFLITGADQNREL

EDC4

366

Q6P2E9
GVRRGWQRVFAALSD

CDC42BPG

961

Q6DT37
KSDSGLAQRRFIRGW

NIBAN3

516

Q86XR2
VRGRVQSFWGSEAAL

LY6G6F

166

Q5SQ64
RGRRSFIFKGEDNWA

ANKRD13A

171

Q8IZ07
VWQRRGSLEGAAAAA

HECW2

736

Q9P2P5
RVGNLISQIRGARAW

HDC

486

P19113
RAAAAQSRWGRASRA

OTOP3

6

Q7RTS5
RQGLSRSLSRNVGVW

HOGA1

11

Q86XE5
ANVWNLLRRFSVDVG

MAGEE2

421

Q8TD90
AYQVLSGGWRNRRVA

KIF15

211

Q9NS87
RFPGRRAWDVTSNIF

NLRP8

91

Q86W28
GQTRATWRVRILSDG

FREM2

1831

Q5SZK8
LWAARTRVAREQGTV

IL17RE

541

Q8NFR9
FAEATSWGRLGARQR

IL17RE

631

Q8NFR9
WARFGRTLAEINANR

DYNC1I2

611

Q13409
QRLLGGRDALFTIQW

MYH7B

851

A7E2Y1
GRDALFTIQWNIRAF

MYH7B

856

A7E2Y1
AVWFGATERRLQRGQ

PLXNB1

1231

O43157
GLAARLQRQFVVRAW

PINK1

76

Q9BXM7
DRVRVNGWATLFLRT

ITGA3

946

P26006
AEARARWGATLRNFS

KCNK12

66

Q9HB15
VQGALWQIFLGRRSL

OR3A2

306

P47893
IGRFWATVAREGNSA

RASGRP4

146

Q8TDF6
QFWGSRSELRRFQDG

NOL6

581

Q9H6R4
FSGVARLAKRWVRAQ

NOL6

851

Q9H6R4
LFVRRNQGAEQWRSA

NCKAP1L

211

P55160
LRVAVRGAFVSLWFA

MYEOV

86

Q96EZ4
WATVGGRRRAVTFSN

LY75

571

O60449
GRRRAVTFSNWNFLE

LY75

576

O60449
NARRFSAGQWEARRG

LAS1L

436

Q9Y4W2
AVQRARWGPRDLATF

AMH

86

P03971
QLDERGRQRGDFSLW

LAG3

121

P18627
RDAWAQRLGAFRASP

AP5B1

6

Q2VPB7
LFWVPRGRRAQSALA

GCAT

11

O75600
LSNVEQAAGLRWSRF

TWNK

381

Q96RR1
QAAGLRWSRFPDLNR

TWNK

386

Q96RR1
GWVVRGVFALALRAA

PLEKHA8

446

Q96JA3
DGAWHSVRIRRQFRN

NRXN1

111

Q9ULB1
RDAFTLQVWLRAEGG

PAPPA

116

Q13219
FLLAAQTRWRRGNTR

HECTD4

1181

Q9Y4D8
GARATLLFERQQWRR

RIBC2

321

Q9H4K1
YVFRVRAQSQEGWGR

ITGB4

1596

P16144
QRFRVAVWTVLAAGR

PHKG2

306

P15735
QVAAARAWRERTGRT

KDM5A

1046

P29375
VLSRWRVFAGAVAQA

HPN

211

P05981
SARLRAFGWQAAARL

PAQR4

171

Q8N4S7
SREVDGWRQLALRSG

HPDL

36

Q96IR7
GWRQLALRSGDAVFL

HPDL

41

Q96IR7
AAEVALSSRGRNFWR

RHOD

186

O00212
LSSRGRNFWRRITQG

RHOD

191

O00212
AELVRAARSWARVGA

BTBD19

191

C9JJ37
AARSWARVGAAVLER

BTBD19

196

C9JJ37
ARRAIRQTWGNESLA

B3GALT2

166

O43825
RWLSRQRNSLGGFAS

CD109

1166

Q6YHK3
DWGATNARVGSLRRV

CRYGD

156

P07320
SSLRSRWGRFLLQRG

IGLL1

61

P15814
LRRRFGDVFSLQLAW

CYP2D6

61

P10635
LLELGRRAWRFGVAA

GAS2L2

151

Q8NHY3
RRAWRFGVAAPTLVQ

GAS2L2

156

Q8NHY3
RFLNGQVVFEAWGRL

DIPK2A

66

Q8NDZ4
RVHLRGSFQVTRAAW

HSD17B4

121

P51659
RESRLFGAVVRWAEA

BTBD1

236

Q9H0C5
WAGLTAQRRRRSSVF

CPAMD8

661

Q8IZJ3
ALLRSNIRRGAQDWA

CCDC183

46

Q5T5S1
AFGTGRAARNRWLAV

DEGS2

96

Q6QHC5
RAARNRWLAVFANLP

DEGS2

101

Q6QHC5
FDWANTSRRGLLLFV

ATAD3C

221

Q5T2N8
QLVQRGWGSALAAAR

CERS1

21

P27544
DQRGALAARWGRTVL

ATG9B

426

Q674R7
GAAWRSRLNSIRNSF

BRSK1

546

Q8TDC3
GSRDGTARIWRFEQL

BRWD1

386

Q9NSI6
LLWRRIARASLNSGF

FBXW4

66

P57775
ANRIVNAAGFWAREV

DMGDH

241

Q9UI17
QGFRFLRRRWGLSSL

MARCHF7

346

Q9H992
LNFPFARRADGRRWS

MAST3

71

O60307
GWLRGAAASRRLQQR

FRAT1

171

Q92837
FRRRGVDVSQVAWQS

KHK

76

P50053
ALRFGRLRNATASLW

LAMB3

596

Q13751
GLVANRGRRFKWAIE

EMC4

6

Q5J8M3
IWITAQRQGLRAGSF

ENPP7

126

Q6UWV6
VRRTQAVELRGQAAW

HELZ2

116

Q9BYK8
QLQAAGRVRWARALY

GRAP2

266

O75791
KANRVWGALRGLETF

HEXB

161

P07686
RVALFRDWIDGVLNN

AZU1

231

P20160
AGRAAGAQRWRSENF

SDC3

41

O75056
RTRVTWRNGLILGFS

SLC22A31

331

A6NKX4
FLQVETRRAGERLGW

RYR1

1611

P21817
AGGRVEWAQARQAFF

CPT1B

386

Q92523
TGFRAWNVQSRGRIF

NPHP1

291

O15259
VRLAQLGAADRQWTR

PKD1

3951

P98161
LGAADRQWTRFVRGR

PKD1

3956

P98161
AAARVWRLNRGLSQA

BCKDHA

6

P12694
GLRRQRNYAGRWDVL

HNRNPUL1

466

Q9BUJ2
AQVAALAAWLLGRRN

HRK

76

O00198
LGGNALDRVARAWFA

NYX

261

Q9GZU5
RGRWAQVFALLAQET

FAM180B

141

Q6P0A1
ARARGWAAAARAAQR

RSAD1

6

Q9HA92
RVLSRARFFEWQSPG

TRMT1

16

Q9NXH9
EGRTAFLWRGNVVLR

TRIM43

161

Q96BQ3
AQRLRQATTRAVEGW

UVSSA

106

Q2YD98
NFQASVGWLNRFRDR

TIGD6

116

Q17RP2
SEAFVQRLLWLRGRG

TIMM29

106

Q9BSF4
RRAFALLGWTGSRQF

DNTT

441

P04053
LLGWTGSRQFERDLR

DNTT

446

P04053
RWGSGTRANVFVQLR

PKDREJ

1241

Q9NTG1
LWVGQDAVRRSVARA

MIIP

21

Q5JXC2
WAGALAQERRFQLEG

SIGLEC6

21

O43699
WDFGIRRRSNTAQRL

MAPKAP1

76

Q9BPZ7
SQRLGLSEARVQVWF

SHOX

151

O15266
QVRGAEASRLWASRL

TEKT5

101

Q96M29
SRAAGLGRRAVVWSL

WIPI2

31

Q9Y4P8
GELSQFNIWDRVLRA

NPTX2

371

P47972
LRAQWGIGDSIRASQ

SESTD1

296

Q86VW0
GFLSFWRGNLANVIR

SLC25A4

66

P12235
LRRRFGDVFSLQLAW

CYP2D7

61

A0A087X1C5
VNWRFLRGIEAQFLA

SMURF2

586

Q9HAU4
TSRGQFLRRGEVFWD

TECTA

261

O75443
WSQRGSQIAFRLQVR

MOXD1

41

Q6UVY6
RLDGSDNRNDFWRLV

SCML2

96

Q9UQR0
IIIWRFAGNFERTVG

RHBDD2

81

Q6NTF9
ARLARAASRLAFQGW

STOX1

51

Q6ZVD7
AASRLAFQGWLRRGV

STOX1

56

Q6ZVD7
AFQGWLRRGVLLVRA

STOX1

61

Q6ZVD7
ADAVARLVARQWAGV

TICAM1

66

Q8IUC6
ALRFAAAASWQVVRG

TINF2

11

Q9BSI4
SAWAGLREAAERRQQ

SPTBN4

1601

Q9H254
LGAGAIYLWSRQQRR

TOMM70

51

O94826
AIFWRREGSQNLLFS

ROBO1

381

Q9Y6N7
QGNLFDFLRLTEWRG

NT5DC2

336

Q9H857
AGSNARAEFWRLRGL

TJP3

566

O95049
RRNPAWSLQAGRLFS

TRAP1

46

Q12931
IRRWSSAQAREFGNL

USP24

2326

Q9UPU5
FWGIALRAQSGDVSR

USP34

1101

Q70CQ2
GTARRNQVWFGLRVP

WNK2

2251

Q9Y3S1
VEAQRRRFLQAGWTA

LCMT2

251

O60294
LGVVGNWLNRSYRRS

RHBDF2

371

Q6PJF5
LEAFGRLWQVQSRLG

UHMK1

16

Q8TAS1
IFNRVFNRLLWSRGQ

TTLL7

766

Q6ZT98
VLSRLGVAGQWRFVD

UCHL1

16

P09936
FSWFNVAEGRTRGRA

XKR8

271

Q9H6D3
FDIAWNGRTGIRQSR

MYO9A

796

B2RTY4