Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	protein refolding	DNAJA1 DNAJA4 DNAJA2	3.07e-05	30	42	3	GO:0042026
Domain	-	DNAJA1 DNAJA4 DNAJA2	3.36e-08	4	39	3	2.10.230.10
Domain	ZF_CR	DNAJA1 DNAJA4 DNAJA2	3.36e-08	4	39	3	PS51188
Domain	DnaJ	DNAJA1 DNAJA4 DNAJA2	3.36e-08	4	39	3	IPR012724
Domain	DnaJ_CXXCXGXG	DNAJA1 DNAJA4 DNAJA2	3.36e-08	4	39	3	PF00684
Domain	DnaJ	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	4.88e-08	48	39	5	PF00226
Domain	DnaJ	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	5.43e-08	49	39	5	SM00271
Domain	DNAJ_1	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	5.43e-08	49	39	5	PS00636
Domain	DNAJ_2	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	5.43e-08	49	39	5	PS50076
Domain	-	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	5.43e-08	49	39	5	1.10.287.110
Domain	DnaJ_domain	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	6.66e-08	51	39	5	IPR001623
Domain	HSP_DnaJ_Cys-rich_dom	DNAJA1 DNAJA4 DNAJA2	8.39e-08	5	39	3	IPR001305
Domain	DnaJ_domain_CS	DNAJC5 DNAJA1 DNAJA4 DNAJA2	2.75e-07	27	39	4	IPR018253
Domain	HSP40/DnaJ_pept-bd	DNAJA1 DNAJA4 DNAJA2	7.01e-07	9	39	3	IPR008971
Domain	DnaJ_C	DNAJA1 DNAJA4 DNAJA2	7.01e-07	9	39	3	IPR002939
Domain	DnaJ_C	DNAJA1 DNAJA4 DNAJA2	7.01e-07	9	39	3	PF01556
Domain	Sec63-dom	ASCC3 SEC63	2.54e-05	4	39	2	IPR004179
Domain	Sec63	ASCC3 SEC63	2.54e-05	4	39	2	PF02889
Domain	Sec63	ASCC3 SEC63	2.54e-05	4	39	2	SM00973
Domain	Rossmann-like_a/b/a_fold	IARS2 NMNAT1	3.63e-03	43	39	2	IPR014729
Domain	-	IARS2 NMNAT1	3.63e-03	43	39	2	3.40.50.620
Pathway	REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND	DNAJA1 DNAJA4 DNAJA2	2.18e-04	52	32	3	MM14949
Pathway	REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND	DNAJA1 DNAJA4 DNAJA2	2.86e-04	57	32	3	M27251
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	IARS2 ASCC3 SEC63 NMNAT1 DNAJA1 PRPF4 SF3B2 SDC4 AZGP1 RPL8 ERLIN1 DNAJA2 RPS8	2.25e-09	1257	43	13	36526897
Pubmed	Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.	DNAJC5 DNAJA1 DNAJA4 DNAJA2	1.46e-08	22	43	4	11147971
Pubmed	Hsp40 chaperones promote degradation of the HERG potassium channel.	DNAJA1 DNAJA4 DNAJA2	1.76e-08	5	43	3	19940115
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TNIK DNAJC5 IARS2 ASCC3 CCDC77 SEC63 DNAJA1 DNAJA4 SF3B2 RPL8 DNAJA2 RPS8	1.60e-07	1487	43	12	33957083
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MICAL3 ASCC3 SEC63 DNAJA1 SF3B2 RPL8 ERLIN1 KIF1B RPS8	1.73e-07	708	43	9	39231216
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TNIK PUM2 DNAJC5 IARS2 SEC63 DNAJA1 RADX SF3B2 DNAJA2	2.32e-07	733	43	9	34672954
Pubmed	Hsp40 proteins phase separate to chaperone the assembly and maintenance of membraneless organelles.	DNAJA1 DNAJA2	1.49e-06	2	43	2	33229560
Pubmed	Identification of signal peptide features for substrate specificity in human Sec62/Sec63-dependent ER protein import.	SEC63 SEC62	1.49e-06	2	43	2	32133789
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	THOP1 ASCC3 DNAJA1 PRPF4 SF3B2 RPL8 ERLIN1 DNAJA2 KIF1B RPS8	2.21e-06	1247	43	10	27684187
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	DNAJA1 PRPF4 DNAJA4 ERLIN1 DNAJA2 RPS8	2.33e-06	313	43	6	16196087
Pubmed	The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.	DNAJA1 DNAJA4 DNAJA2	3.06e-06	23	43	3	21231916
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ASCC3 NMNAT1 DNAJA1 PRPF4 RADX RPL8 DNAJA2 RPS8	3.66e-06	759	43	8	35915203
Pubmed	Mammalian Sec61 is associated with Sec62 and Sec63.	SEC63 SEC62	4.48e-06	3	43	2	10799540
Pubmed	CK2 phosphorylation of human Sec63 regulates its interaction with Sec62.	SEC63 SEC62	4.48e-06	3	43	2	23287549
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ADNP2 ASCC3 DNAJA1 SF3B2 SDC4 AZGP1 RPL8 ERLIN1 DNAJA2 RPS8	4.56e-06	1353	43	10	29467282
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	DNAJA1 SF3B2 RPL8 DNAJA2 RPS8	7.66e-06	220	43	5	34091597
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PI4K2B MICAL3 IARS2 ASCC3 SEC63 CABIN1 DNAJA1 ERLIN1 DNAJA2 SEC62	7.88e-06	1440	43	10	30833792
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TNIK MICAL3 IARS2 CCDC77 DNAJA1 ERLIN1 DNAJA2 KIF1B	8.59e-06	853	43	8	28718761
Pubmed	Functional divergence between co-chaperones of Hsc70.	DNAJA1 DNAJA2	8.94e-06	4	43	2	18684711
Pubmed	Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70.	DNAJA1 DNAJA2	8.94e-06	4	43	2	10816573
Pubmed	Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier.	SEC63 SEC62	8.94e-06	4	43	2	29719251
Pubmed	Optimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1.	DNAJA1 DNAJA2	8.94e-06	4	43	2	22085931
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ASCC3 DNAJA1 PRPF4 SF3B2 RPL8 DNAJA2 RPS8	1.23e-05	638	43	7	33239621
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	NMNAT1 PRPF4 SF3B2 SDC4 RPL8	1.45e-05	251	43	5	28077445
Pubmed	Novel role of HSP40/DNAJ in the regulation of HIV-1 replication.	DNAJC5 DNAJA1	1.49e-05	5	43	2	24047968
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	IARS2 ASCC3 DNAJA1 RADX SF3B2 RPL8 ERLIN1 DNAJA2 RPS8	1.90e-05	1257	43	9	37317656
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	TNIK IARS2 ASCC3 DNAJA1 PRPF4 DNAJA2 RPS8	2.31e-05	704	43	7	29955894
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TNIK THOP1 SEC63 DNAJA1 DNAJA4 SDC4 ERLIN1 DNAJA2 SEC62	2.43e-05	1297	43	9	33545068
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	SEC63 DNAJA1 SF3B2 AZGP1 RPL8 ERLIN1 DNAJA2 RPS8	2.49e-05	989	43	8	36424410
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	PUM2 DNAJA1 PRPF4 SF3B2 RPL8 DNAJA2 RPS8	2.51e-05	713	43	7	29802200
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	DNAJA1 PRPF4 RADX RPL8 DNAJA2 RPS8	2.74e-05	483	43	6	36912080
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	PUM2 ASCC3 SEC63 PRPF4 SF3B2 RPL8 ERLIN1 RPS8 BRD9	2.76e-05	1318	43	9	30463901
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	DNAJA1 DNAJA4 SF3B2 RPL8 DNAJA2 RPS8	3.11e-05	494	43	6	26831064
Pubmed	A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.	PRPF4 DNAJA4 ERLIN1 RPS8	4.86e-05	162	43	4	21890473
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	IARS2 SEC63 DNAJA1 PRPF4 SF3B2 AZGP1 RPL8 DNAJA2 RPS8	5.07e-05	1425	43	9	30948266
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	IARS2 ASCC3 DNAJA1 SF3B2 RPL8 KIF1B RPS8	5.58e-05	809	43	7	32129710
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	DNAJA1 SF3B2 AZGP1 RPL8 DNAJA2 RPS8	6.11e-05	558	43	6	27591049
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	IARS2 DNAJA1 RPL8 ERLIN1 DNAJA2 RPS8	6.55e-05	565	43	6	33567341
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF721 ZNF99	6.68e-05	10	43	2	18588511
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	ASCC3 SF3B2 AZGP1 RPL8 RPS8	7.74e-05	357	43	5	37059091
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF721 ZNF99	8.15e-05	11	43	2	15469996
Pubmed	Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.	DNAJA1 DNAJA2	8.15e-05	11	43	2	24318877
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	IARS2 DNAJA1 DNAJA4 RADX DNAJA2	8.37e-05	363	43	5	25036637
Pubmed	Revealing A-Raf functions through its interactome.	NEK1 DNAJA1 DNAJA2 RPS8	8.48e-05	187	43	4	29777862
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	ASCC3 DNAJA1 SF3B2 RPL8 DNAJA2 RPS8	9.20e-05	601	43	6	33658012
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	ASCC3 PRPF4 SF3B2 AZGP1 RPL8 RPS8	9.54e-05	605	43	6	28977666
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	ASCC3 SEC63 RPL8 SEC62 RPS8	9.75e-05	375	43	5	32788342
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	ASCC3 NMNAT1 DNAJA1 SF3B2 RPL8 RPS8	1.04e-04	615	43	6	31048545
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	TNIK RPL8 DNAJA2 KIF1B RPS8 EHD3	1.10e-04	621	43	6	22794259
Pubmed	Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.	SEC63 SEC62	1.15e-04	13	43	2	22375059
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF721 ZNF99	1.15e-04	13	43	2	19850934
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	DNAJA1 PRPF4 SF3B2 RPL8 DNAJA2 RPS8	1.28e-04	639	43	6	23443559
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TNIK NEK1 MICAL3 ASCC3	1.30e-04	209	43	4	36779422
Pubmed	Proteomic analysis identifies novel binding partners of BAP1.	DNAJA1 SF3B2 DNAJA2	1.35e-04	80	43	3	34591877
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK PUM2 NEK1 IARS2 SF3B2 RPL8 RPS8	1.37e-04	934	43	7	33916271
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	SF3B2 RPL8 ERLIN1 DNAJA2 RPS8	1.45e-04	408	43	5	33766124
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	PUM2 DNAJA1 SF3B2 RPL8 DNAJA2 RPS8	1.47e-04	655	43	6	35819319
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	SEC63 SF3B2 RPL8 ERLIN1 DNAJA2 RPS8	1.49e-04	657	43	6	36180527
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	ADNP2 PUM2 DNAJA1 DNAJA2 BRD9	1.50e-04	411	43	5	35182466
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF721 ZNF99	1.55e-04	15	43	2	15885501
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ADNP2 THOP1 CABIN1 DNAJA1 SF3B2 DNAJA2 KIF1B STAT6	1.56e-04	1285	43	8	35914814
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	DNAJA1 SF3B2 RPL8 DNAJA2	1.61e-04	221	43	4	29991511
Pubmed	Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis.	DNAJA1 AZGP1 RPL8 RPS8	1.61e-04	221	43	4	31796584
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	DNAJA1 RPL8 ERLIN1 DNAJA2 RPS8	1.62e-04	418	43	5	35338135
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	DNAJA1 SF3B2 DNAJA2 RPS8 BRD9	1.62e-04	418	43	5	32552912
Pubmed	Nucleolar proteome dynamics.	DNAJA1 PRPF4 SF3B2 RPL8 RPS8	1.64e-04	419	43	5	15635413
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	SEC63 DNAJA1 PRPF4 DNAJA4 SF3B2 DNAJA2 RPS8	1.73e-04	971	43	7	33306668
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	DNAJA1 PRPF4 SF3B2 RPL8 RPS8	1.75e-04	425	43	5	21081503
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	DNAJA1 PRPF4 SF3B2 RPL8 DNAJA2 RPS8	1.77e-04	678	43	6	30209976
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ASCC3 DNAJA1 PRPF4 SF3B2 AZGP1 RPL8 DNAJA2 RPS8	2.02e-04	1335	43	8	29229926
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	ASCC3 SEC63 DNAJA1 DNAJA2	2.11e-04	237	43	4	29564676
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	PUM2 DNAJA1 PRPF4 SF3B2 RPL8 RPS8	2.34e-04	714	43	6	28302793
Pubmed	Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.	DNAJA1 RPL8 DNAJA2 RPS8	2.35e-04	244	43	4	30349055
Pubmed	Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.	DNAJA1 RPL8 ERLIN1 RPS8	2.35e-04	244	43	4	28902428
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	IARS2 DNAJA1 SF3B2 SDC4 AZGP1 ERLIN1 DNAJA2 KIF1B	2.37e-04	1367	43	8	32687490
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ASCC3 DNAJA1 PRPF4 SF3B2 RPL8 ERLIN1 RPS8	2.40e-04	1024	43	7	24711643
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TNIK ASCC3 CCDC77 SEC63 NMNAT1 SF3B2 ERLIN1 SEC62	2.42e-04	1371	43	8	36244648
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	DNAJA1 SF3B2 RPL8 ERLIN1 DNAJA2 RPS8	2.54e-04	725	43	6	27025967
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TNIK NEK1 PRPF4 DNAJA4 RPL8 MKS1 RPS8	2.61e-04	1038	43	7	26673895
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	NEK1 IARS2 RPL8 DNAJA2 RPS8	2.62e-04	464	43	5	32457219
Pubmed	The role of RNF149 in the pre-emptive quality control substrate ubiquitination.	SEC63 SEC62	2.80e-04	20	43	2	37031316
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	PUM2 ASCC3 RPL8 RPS8	2.91e-04	258	43	4	37794589
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	THOP1 DNAJA1 PRPF4 DNAJA4 SF3B2 RPL8 DNAJA2 RPS8	3.00e-04	1415	43	8	28515276
Pubmed	Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry.	DNAJA1 RPL8 RPS8	3.02e-04	105	43	3	24625528
Pubmed	Human transcription factor protein interaction networks.	PUM2 ZNF721 CABIN1 DNAJA1 RADX DNAJA2 RPS8 BRD9	3.20e-04	1429	43	8	35140242
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	ASCC3 DNAJA1 RPL8 DNAJA2 RPS8	3.24e-04	486	43	5	30940648
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	DNAJA1 AZGP1 RPL8 DNAJA2 RPS8	3.30e-04	488	43	5	31324722
Pubmed	Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.	DNAJA1 SF3B2 AZGP1 SEC62	3.41e-04	269	43	4	30442662
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	IARS2 THOP1 SEC63 GVINP1 SF3B2 RPL8 SEC62 RPS8	3.55e-04	1451	43	8	30550785
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	NMNAT1 DNAJA1 PRPF4 AZGP1 ERLIN1	3.56e-04	496	43	5	31343991
Pubmed	Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation.	SF3B2 RPL8 RPS8	3.65e-04	112	43	3	28416769
Pubmed	Physiological and pathophysiological characteristics of ataxin-3 isoforms.	DNAJA1 SF3B2 DNAJA2 RPS8	4.02e-04	281	43	4	30455355
Pubmed	MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.	RPL8 ERLIN1 RPS8	4.05e-04	116	43	3	36307841
Pubmed	c-IAP1 binds and processes PCSK9 protein: linking the c-IAP1 in a TNF-α pathway to PCSK9-mediated LDLR degradation pathway.	DNAJA1 DNAJA2	4.05e-04	24	43	2	23085658
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	ASCC3 DNAJA1 PRPF4 DNAJA2	4.07e-04	282	43	4	23667531
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PUM2 IARS2 CCDC77 SEC63 DNAJA1 ERLIN1 DNAJA2 RPS8	4.35e-04	1496	43	8	32877691
Pubmed	MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.	DNAJA1 SF3B2 DNAJA2 RPS8	4.35e-04	287	43	4	36180891
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	IARS2 DNAJA1 AZGP1 RPL8 DNAJA2 RPS8	4.38e-04	803	43	6	36517590
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	DNAJA1 SF3B2 DNAJA2	4.47e-04	120	43	3	27320910
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	PUM2 ASCC3 RADX SF3B2 RPL8 RPS8	4.49e-04	807	43	6	22681889
Interaction	DNAJA2 interactions	PI4K2B DNAJC5 IARS2 ASCC3 DNAJA1 MAP2K5 DNAJA4 RADX DNAJA2 MKS1 BRD9	9.68e-09	542	42	11	int:DNAJA2
Interaction	DNAJA4 interactions	DNAJC5 DNAJA1 DNAJA4 RADX DNAJA2	6.18e-07	79	42	5	int:DNAJA4
Interaction	DNAJC7 interactions	DNAJC5 IARS2 ASCC3 DNAJA1 DNAJA4 RADX DNAJA2 MKS1	2.31e-06	425	42	8	int:DNAJC7
Interaction	BAG2 interactions	TNIK PI4K2B DNAJC5 ASCC3 DNAJA1 MAP2K5 DNAJA4 DNAJA2 MKS1	4.30e-06	622	42	9	int:BAG2
Interaction	KCNA3 interactions	MICAL3 ASCC3 SEC63 DNAJA1 SF3B2 RPL8 ERLIN1 KIF1B RPS8 EHD3	9.01e-06	871	42	10	int:KCNA3
Interaction	GPR183 interactions	SEC63 SDC4 SEC62	7.30e-05	39	42	3	int:GPR183
Interaction	SYNE2 interactions	TNIK THOP1 PRPF4 SEC62 MKS1	8.88e-05	219	42	5	int:SYNE2
Interaction	PYHIN1 interactions	NMNAT1 CABIN1 PRPF4 SF3B2 SDC4 RPL8	9.21e-05	358	42	6	int:PYHIN1
Interaction	CASK interactions	TNIK DNAJC5 SF3B2 SDC4 KIF1B	9.26e-05	221	42	5	int:CASK
Interaction	HPSE interactions	DNAJA1 DNAJA4 DNAJA2	9.80e-05	43	42	3	int:HPSE
Interaction	CC2D2A interactions	MICAL3 ASCC3 MKS1	1.05e-04	44	42	3	int:CC2D2A
Interaction	RADX interactions	DNAJA4 RADX DNAJA2	1.45e-04	49	42	3	int:RADX
Interaction	FBXW7 interactions	IARS2 METTL5 ASCC3 DNAJA1 PRPF4 SF3B2 RPL8 DNAJA2 RPS8 BRD9	1.53e-04	1215	42	10	int:FBXW7
Interaction	HECTD1 interactions	PUM2 ASCC3 NMNAT1 DNAJA1 PRPF4 RADX RPL8 DNAJA2 RPS8	1.58e-04	984	42	9	int:HECTD1
Interaction	SLX4 interactions	ASCC3 CCDC77 PRPF4 SF3B2 AZGP1 RPL8 RPS8	1.63e-04	572	42	7	int:SLX4
Interaction	BRCA1 interactions	CABIN1 DNAJA1 DNAJA4 SF3B2 RPL8 ERLIN1 DNAJA2 KIF1B RPS8 BRD9	1.91e-04	1249	42	10	int:BRCA1
Interaction	DDRGK1 interactions	SEC63 NMNAT1 DNAJA1 PRPF4 SF3B2 RPL8 ERLIN1 DNAJA2 SEC62 RPS8	1.91e-04	1249	42	10	int:DDRGK1
Interaction	NPM3 interactions	CEP126 ASCC3 NMNAT1 RPL8 RPS8	2.05e-04	262	42	5	int:NPM3
Interaction	USP36 interactions	METTL5 DNAJA1 PRPF4 RADX RPL8 DNAJA2 RPS8	2.16e-04	599	42	7	int:USP36
Interaction	ATRX interactions	NEK1 IARS2 CEP126 CABIN1 BRD9	2.24e-04	267	42	5	int:ATRX
Interaction	UFL1 interactions	IARS2 SEC63 DNAJA1 RADX SF3B2 RPL8 DNAJA2 SEC62 RPS8	2.24e-04	1031	42	9	int:UFL1
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	DNAJC5 SEC63 DNAJA1 DNAJA4 DNAJA2	6.05e-09	49	25	5	584
Coexpression	GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP	TNIK PUM2 CCDC77 DNAJA1 SF3B2 EHD3	8.82e-07	200	43	6	M5613
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTLL8 SDC4 RPL8 RPS8	9.53e-06	138	43	4	615822e542f12aa83df1561e262b8d72bdefc60e
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL8 MKS1 RPS8 EHD3	2.27e-05	172	43	4	5b1f6d4e09e6465acb80b58846ad387e38b155ab
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP92 AZGP1 RPL8 RPS8	2.48e-05	176	43	4	12bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK ENTHD1 DNAJA4 EHD3	2.53e-05	177	43	4	d8b1bbc224d062a57a6ad40b4b2af5d6e0fe63b3
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK ENTHD1 DNAJA4 EHD3	2.53e-05	177	43	4	6d86b2f97426b552dff5ce6ddf0ead1285ed618e
ToppCell	Immune_cells-T_cells\|Immune_cells / Lineage and Cell class	TNIK RPL8 RPS8 EHD3	2.59e-05	178	43	4	af420242277e2a4e2524002a2914b0538f79a134
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B SDC4 RPL8 RPS8	3.01e-05	185	43	4	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA1 SDC4 RPL8 RPS8	3.08e-05	186	43	4	e3807508a5da6c8c7081129a5f785ccecaf5ebba
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B SDC4 RPL8 RPS8	3.08e-05	186	43	4	1cbb1a1c4f0f6078e9c7b4e0dc93d6b6de7e57db
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B SDC4 RPL8 RPS8	3.41e-05	191	43	4	4fcbc214853e115608b3be7b35639247ae41c9dc
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK PI4K2B SDC4 RPS8	3.77e-05	196	43	4	3dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B SDC4 RPL8 RPS8	3.93e-05	198	43	4	d5e91d1057e71b6a336eec95e44b2e7fe6b2c6ef
ToppCell	mLN-B_cell-Follicular_B_cell\|mLN / Region, Cell class and subclass	MICAL3 RPL8 SEC62 RPS8	4.08e-05	200	43	4	7f5dbd06f8643230dba45d6fa0258a13cb71f681
ToppCell	Transverse-B_cell-B_cell_memory\|B_cell / Region, Cell class and subclass	DNAJA1 DNAJA4 RPL8 RPS8	4.08e-05	200	43	4	a92b5f883d95b6a3db8ceccf294aa503839f7ed3
ToppCell	mLN-(2)_B_cell-(23)_Follicular_B_cell\|mLN / shred on region, Cell_type, and subtype	MICAL3 RPL8 SEC62 RPS8	4.08e-05	200	43	4	659b49eeeb3e96b0a52663e60336ca4d76c83cfc
ToppCell	Epithelial-B_(AT1-AT2-progenitors)\|World / shred on cell class and cell subclass (v4)	PI4K2B ARHGAP8 SDC4	3.76e-04	146	43	3	4511916904c1fac252cb68e871b782207f8137b3
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NMNAT1 DNAJA4 RPS8	3.83e-04	147	43	3	55f4b3289094a1eab6d7a6c8f214ec7b031edfa8
ToppCell	Epithelial-Epithelial-B_(AT1-AT2-progenitors)\|Epithelial / shred on cell class and cell subclass (v4)	PI4K2B CCDC77 ARHGAP8	4.39e-04	154	43	3	770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCell	critical-Epithelial-Basal\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TNIK RPL8 RPS8	4.47e-04	155	43	3	cb6fbd36aa1fab29a1667ee13441bddc3d28846f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT1_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDC4 RPL8 RPS8	5.18e-04	163	43	3	fd35f1237c23367753ac2bc3e893f0e3c714129c
ToppCell	ILEUM-non-inflamed-(2)_B_cell-(2)_Naive_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPL8 SEC62 RPS8	5.18e-04	163	43	3	9add806d706f7170a49b2c2dcc14343e9befd26c
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAJC5 ARHGAP8 AZGP1	5.37e-04	165	43	3	34fd00be2b28716c871ad9fb356de84a299a0c01
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADNP2 PRPF4 SDC4	5.75e-04	169	43	3	befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADNP2 PRPF4 SDC4	5.75e-04	169	43	3	d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCell	control-Myeloid-Resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL8 RPS8	5.82e-04	37	43	2	b7364793f8ba6ca50ab0bb3742b11d9d27a7439a
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_Central_Memory_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DNAJA1 RPL8 RPS8	5.85e-04	170	43	3	d4c95c317a731c0db2c213c64cb87da636d30f00
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNIK DNAJA4 EHD3	5.95e-04	171	43	3	a8adce007ff4c713f71f2359b40cb3575b28c98d
ToppCell	facs-Thymus-Flowthrough-24m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL8 RPS8 EHD3	5.95e-04	171	43	3	1064c20c37fae6cefb2eb4fa0628e4037a78179c
ToppCell	facs-Thymus-Flowthrough-24m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL8 RPS8 EHD3	5.95e-04	171	43	3	e2b72282244dee008e3b5d03667be9f26b7c2f6d
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GVINP1 RPL8 RPS8	6.06e-04	172	43	3	09c03cc7717373f10e51281be76d53979fcb7ccd
ToppCell	MS-CD8-proli_CD4\|MS / Condition, Cell_class and T cell subcluster	MICAL3 CCDC77 CABIN1	6.06e-04	172	43	3	0b6dd257110b3f17fa71ab18a165b091a9d5ae9a
ToppCell	droplet-Thymus-nan-24m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA4 RPL8 RPS8	6.16e-04	173	43	3	6bb98b0776151d726c2962a96f3411213aa86b21
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA4 RPL8 RPS8	6.37e-04	175	43	3	a7269351ce6afbd469c79174aa88be84d4f7e0b6
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNIK DNAJA1 KIF1B	6.37e-04	175	43	3	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN4\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA4 RPL8 RPS8	6.37e-04	175	43	3	1fa85b28d0e4d1d8d584516325a46f69dc6fbe54
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AZGP1 RPL8 RPS8	6.69e-04	178	43	3	415a02ad14df9deba988990118b00fb84ee524a8
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPL8 RPS8 EHD3	6.69e-04	178	43	3	61363c3365d3e191c47be1b2a35fa8afbfa64ff2
ToppCell	droplet-Thymus-nan-24m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	6.69e-04	178	43	3	9c6cb39647d5a040ae325bc75148dfddbff7621e
ToppCell	C_00\|World / shred on cell type and cluster	RANBP17 ARHGAP8 RPS8	6.80e-04	179	43	3	da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCell	ASK454-Epithelial-Ciliated\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	NEK1 CFAP92 DNAJA4	6.80e-04	179	43	3	f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCell	367C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	THOP1 CEP126 SEC63	6.80e-04	179	43	3	5aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MICAL3 ARHGAP8 KIF1B	6.91e-04	180	43	3	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GVINP1 BRD9 EHD3	6.91e-04	180	43	3	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MICAL3 ARHGAP8 KIF1B	6.91e-04	180	43	3	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GVINP1 BRD9 EHD3	6.91e-04	180	43	3	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AZGP1 RPL8 RPS8	7.02e-04	181	43	3	cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCell	facs-Spleen-nan-3m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK KIF1B EHD3	7.02e-04	181	43	3	be7c7db6b99603759593e6f79cdcaa4bbf234cb7
ToppCell	droplet-Thymus-nan-24m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.02e-04	181	43	3	2a3092fbadd18967199f1203c11f0dd956417254
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AZGP1 RPL8 RPS8	7.13e-04	182	43	3	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL8 RPS8 EHD3	7.13e-04	182	43	3	c1665cd9b28fec4bfe4e3981d7992d660f37b97f
ToppCell	Int-URO-Lymphocyte-B-B_naive\|Int-URO / Disease, Lineage and Cell Type	MICAL3 SEC62 RPS8	7.13e-04	182	43	3	af7482c63e87a53cf686200a8f4d5b9749235dcd
ToppCell	droplet-Pancreas-PANCREAS-30m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AZGP1 RPL8 RPS8	7.13e-04	182	43	3	cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCell	Influenza_Severe-B_naive\|World / Disease group and Cell class	MICAL3 RPL8 RPS8	7.13e-04	182	43	3	e4885a5e6065c9c403cb2d305228691d6ae4ecb6
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	TNIK MICAL3 DNAJA4	7.13e-04	182	43	3	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	MICAL3 IARS2 MAP2K5	7.13e-04	182	43	3	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	facs-Spleen\|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.25e-04	183	43	3	d8e87234d2fc2059536ed456993ab0557d118361
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.25e-04	183	43	3	7534587fa35837c0aaca93c542f2eee493eba637
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK KIF1B EHD3	7.36e-04	184	43	3	c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.36e-04	184	43	3	a740ceffa62175578e6cff62da1f8dfaf40098e5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP92 TTLL8 SDC4	7.36e-04	184	43	3	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA1 RPL8 RPS8	7.36e-04	184	43	3	46e77d879d6f8f779a00c5683611ec9b9e8acc53
ToppCell	ILEUM-non-inflamed-(1)_Central_Memory_T_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DNAJA1 RPL8 RPS8	7.36e-04	184	43	3	62b7a1a9b61e29b7f2ea144c9096db80b49fe320
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA1 RPL8 RPS8	7.36e-04	184	43	3	bb416c96ea5edfa46819fe79888b223d09278943
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP92 TTLL8 SDC4	7.36e-04	184	43	3	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	droplet-Thymus-nan-24m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.48e-04	185	43	3	a92bd84e44fc992b7eeefaa2ff8091ed09f0df00
ToppCell	Bac-SEP-Lymphocyte-B-B_naive\|Bac-SEP / Disease, Lineage and Cell Type	RPL8 SEC62 RPS8	7.48e-04	185	43	3	4d9e1eeb353c0b1f82f557856e99c8bf04aa2a7f
ToppCell	droplet-Thymus-nan-24m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.48e-04	185	43	3	877eb127ac797f8a1e1a9e0049fa16cae16cfa35
ToppCell	droplet-Thymus-nan-24m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDC4 RPL8 RPS8	7.48e-04	185	43	3	d7fed17356f8bf5900fd106f25b4f7501ad7b590
ToppCell	droplet-Spleen-nan-3m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJA1 RPL8 RPS8	7.60e-04	186	43	3	26f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL8 RPS8 EHD3	7.60e-04	186	43	3	b999b9bed8357083997cacf5dc64530ddedc056e
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ASCC3 SEC63 ERLIN1	7.60e-04	186	43	3	bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK RPL8 RPS8	7.72e-04	187	43	3	1387981d224cb9e846ed18e366736855a4eb827e
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	TNIK DNAJA1 DNAJA4	7.72e-04	187	43	3	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL8 RPS8 EHD3	7.84e-04	188	43	3	5108238b7b8e9645c0cd75f8405a4638617e74a2
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL8 RPS8 EHD3	7.84e-04	188	43	3	467773d1e6b4828495a62f3b92996964d1c94b97
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPL8 RPS8 EHD3	7.84e-04	188	43	3	ac267799fc1389b901d20b5d24c3179f00ca646f
ToppCell	Multiple_Sclerosis-Lymphocyte-B-B_naive\|Multiple_Sclerosis / Disease, Lineage and Cell Type	MICAL3 RPL8 SEC62	7.84e-04	188	43	3	19b7f92ca46c15b2ac7bba8827eeb85496cdc5f0
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RANBP17 ARHGAP8 SDC4	7.84e-04	188	43	3	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Mesenchymal_cells-Myofibroblasts\|Mesenchymal_cells / Lineage and Cell class	SDC4 RPL8 RPS8	7.96e-04	189	43	3	f5322429963257cfd3fd813d7b7d273d3d12d622
ToppCell	E18.5\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PI4K2B SDC4 RPL8	8.08e-04	190	43	3	fe9678be25e29a09c0b9ac59da4ee3a29f22dde1
ToppCell	ICU-SEP-Lymphocyte-B\|ICU-SEP / Disease, Lineage and Cell Type	RPL8 SEC62 RPS8	8.08e-04	190	43	3	a861506520780932b4630fa285c1e4a77134a505
ToppCell	ASK454-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	NEK1 CFAP92 DNAJA4	8.08e-04	190	43	3	5cea6480f08253d7adf484e511d3fdfa96641268
ToppCell	severe-B_naive\|severe / disease stage, cell group and cell class	MICAL3 SEC62 RPS8	8.08e-04	190	43	3	2430a1fd18385305bf1b604747ff64026a8d5edf
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SDC4 AZGP1 RPL8	8.20e-04	191	43	3	1c46f4eabc1fd790069d5d8b29580d3904e2ef41
ToppCell	(4)_B_mantle\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	RPL8 SEC62 RPS8	8.20e-04	191	43	3	5dab7f26c59838080787efad963b9cfcfa9a5f13
ToppCell	ICU-NoSEP-Lymphocyte-B-B_naive\|ICU-NoSEP / Disease, Lineage and Cell Type	RPL8 SEC62 RPS8	8.20e-04	191	43	3	f430961a94890fe8755d22e53836be39cb08e153
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPL8 RPS8 EHD3	8.20e-04	191	43	3	31169e01072e5fea364178264a35754b6cf2c93b
ToppCell	ICU-SEP-Lymphocyte-B-B_naive\|ICU-SEP / Disease, Lineage and Cell Type	RPL8 SEC62 RPS8	8.20e-04	191	43	3	a090f9ea58a700c995c4ad35eeebb699f07040f7
ToppCell	(100)_CD19+_Naive_B_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	MICAL3 RPL8 RPS8	8.33e-04	192	43	3	ae7e6ed7b6cc1dd45bc0547783515beecad7792a
ToppCell	B_cell_maturation-Naive_B_cell\|World / Lineage and Cell class	MICAL3 RPL8 RPS8	8.33e-04	192	43	3	58267a11c938a380c6e26f4e4ce63f3b4be79fdc
ToppCell	ICU-NoSEP-Lymphocyte-B\|ICU-NoSEP / Disease, Lineage and Cell Type	RPL8 SEC62 RPS8	8.33e-04	192	43	3	b73423b3845ab21827b5101b59cb33a28fe20fe1
ToppCell	(4)_B_cells\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	RPL8 SEC62 RPS8	8.33e-04	192	43	3	60f348e38d09312136b077f6a298258475cedd0a
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MICAL3 RPL8 RPS8	8.33e-04	192	43	3	0bda96d8f223e8fa9caf935079ab202fc5c812ee
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	DNAJA4 SDC4 RPS8	8.33e-04	192	43	3	f40a7f8771aa9891a6fd59b9c8eac2fd792efa9b
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MICAL3 RPL8 RPS8	8.33e-04	192	43	3	4c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCell	normal-na-Lymphocytic_B-B_naive\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MICAL3 RPL8 SEC62	8.45e-04	193	43	3	98279a3c69f1df062c4a8333e46c8fd649bf86b1
ToppCell	normal-na-Lymphocytic_B-B_naive-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MICAL3 RPL8 SEC62	8.45e-04	193	43	3	dd199163fc13f3d411fe741cf003237064349e22
ToppCell	ILEUM-inflamed-(1)_Central_Memory_T_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DNAJA1 RPL8 RPS8	8.45e-04	193	43	3	c4975fff8927649669e93d3e04308cbf4a48e3e9
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK SDC4 RPS8	8.45e-04	193	43	3	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	ILEUM-inflamed-(2)_B_cell-(2)_Naive_B_cells\|(2)_B_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RPL8 SEC62 RPS8	8.58e-04	194	43	3	a89e67a40382600739be92e395bf47dd44aa4122
Disease	Polycystic Kidney - body part	SEC63 MKS1	1.88e-05	5	41	2	C1567435
Disease	Alzheimer's disease (implicated_via_orthology)	DNAJA1 DNAJA4 DNAJA2	6.92e-05	57	41	3	DOID:10652 (implicated_via_orthology)
Disease	prostate carcinoma (is_implicated_in)	AZGP1 STAT6	1.46e-04	13	41	2	DOID:10286 (is_implicated_in)
Disease	prostate cancer (is_marker_for)	MAP2K5 AZGP1 STAT6	1.33e-03	156	41	3	DOID:10283 (is_marker_for)
Disease	alcohol consumption measurement	RANBP17 ENTHD1 MICAL3 CCDC77 MAP2K5 ERLIN1 STAT6	1.48e-03	1242	41	7	EFO_0007878
Disease	restless legs syndrome	RANBP17 MAP2K5	2.13e-03	49	41	2	EFO_0004270

Protein segments in the cluster

Peptide	Gene	Start	Entry
VYYKLAKKILHAGFK	BRD9	221	Q9H8M2
HKLTPEYLELKKYQA	ERLIN1	276	O75477
YPKKLSKANFHLIYK	GVINP1	871	Q7Z2Y8
KLHPSKELLEYYQKK	CCDC77	51	Q9BR77
EIKKAYRKLALKYHP	DNAJA4	21	Q8WW22
GKYASLIEKYKKHPK	CFAP92	91	Q9ULG3
ELKKAYRKLALKYHP	DNAJA1	21	P31689
YFHKKPYPSKKEIEL	ADNP2	1061	Q6IQ32
VTYLFKHIAKEGKKP	RANBP17	941	Q9H2T7
YGKHILAKLEKYYLK	PUM2	1036	Q8TB72
ILHKSKLRYYGKPDK	RADX	241	Q6NSI4
ASEKKYKLPKFGRLH	ENTHD1	181	Q8IYW4
LKPKDYRSFYHKLKS	MICAL3	41	Q7RTP6
GIPLAYKKYGDKKLH	NEK1	316	Q96PY6
VVSKKGYLHFKEPLY	KIF1B	1701	O60333
YKAYHVPSGKILAVK	MAP2K5	181	Q13163
IKKSYRKLALKYHPD	DNAJC5	31	Q9H3Z4
DKPILKAGRAYHKYK	RPL8	176	P62917
KYALEKVPKVGRKFH	PI4K2B	231	Q8TCG2
ELRYDLPASYKFHKK	METTL5	181	Q9NRN9
KAYRKLAKEYHPDKN	DNAJA2	26	O60884
LKHPGLILKYSTYKN	CABIN1	81	Q9Y6J0
KSILKKESKYEHGYL	CEP126	576	Q9P2H0
EEKYTYKALPKPASH	CCDC168	3316	Q8NDH2
GKRKPYHKKRKYELG	RPS8	16	P62241
DEGSYDLGKKPIYKK	SDC4	176	P31431
KKPHIYYGSLEEKER	PRPF4	26	O43172
KNLLKEEKLVHSYPY	IARS2	451	Q9NSE4
KKLYKSKLLPLEEHY	EHD3	26	Q9NZN3
HDIKKDFYKKFLYEP	ASCC3	1706	Q8N3C0
KPKLTIHGDLYYEGK	SF3B2	581	Q13435
IIHTEDKPYKYKKCG	ZNF99	221	A8MXY4
KPLYHYKEGMSPSEK	TNIK	516	Q9UKE5
AIKEKKIFSIYGHYP	TTLL8	51	A6PVC2
GPYKKLGYKKYEHVL	MKS1	211	Q9NXB0
LYTHEYKGPKADLKK	SEC62	281	Q99442
YPKKPKDEAFRSHYK	STAT6	616	P42226
LNEYKKIHTGDKPYK	ZNF721	196	Q8TF20
KKQYRLLSLKYHPDK	SEC63	121	Q9UGP8
KPLISHKFGKKVIYF	ARHGAP8	156	P85298
KKLKCLAYDFYPGKI	AZGP1	221	P25311
EDGKLKVTLKYPHYF	THOP1	211	P52888
VGDAYKKKGLIPAYH	NMNAT1	51	Q9HAN9