Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglutamate receptor activity

GRID1 GRID2 GRIK1 GRIK2

1.50e-0627634GO:0008066
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRID1 GRID2 GRIK1 GRIK2

3.13e-0557634GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRID1 GRID2 GRIK1 GRIK2

3.84e-0560634GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRID1 GRID2 GRIK1 GRIK2

5.27e-0565634GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRID1 GRID2 GRIK1 GRIK2

5.27e-0565634GO:0022824
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRID1 GRID2 GRIK1 GRIK2

9.24e-0575634GO:0098960
GeneOntologyMolecularFunctionglutathione peroxidase activity

GPX6 GPX3 GPX4

9.27e-0528633GO:0004602
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRID1 GRID2 GRIK1 GRIK2

1.02e-0477634GO:0005230
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK1 GRIK2

1.46e-046632GO:0015277
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIK1 GRIK2

2.04e-047632GO:0005234
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRID1 GRID2 GRIK1 GRIK2

2.81e-04100634GO:0030594
GeneOntologyMolecularFunctionselenium binding

GPX3 GPX4

4.34e-0410632GO:0008430
GeneOntologyMolecularFunctionperoxidase activity

GPX6 GPX3 GPX4

1.14e-0365633GO:0004601
GeneOntologyMolecularFunctionoxidoreductase activity, acting on peroxide as acceptor

GPX6 GPX3 GPX4

1.24e-0367633GO:0016684
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK1 GRIK2

1.29e-0317632GO:0004970
GeneOntologyMolecularFunctionligand-gated sodium channel activity

GRIK1 GRIK2

1.45e-0318632GO:0015280
GeneOntologyMolecularFunctionankyrin binding

SPTBN1 OBSCN

2.37e-0323632GO:0030506
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIK1 GRIK2

2.59e-0324632GO:0099507
GeneOntologyMolecularFunctionoxidoreductase activity

DMGDH FADS1 MAOA GPX6 GPX3 GPX4 KDM2B STEAP1

2.71e-03766638GO:0016491
GeneOntologyMolecularFunctionscaffold protein binding

GRID2 GRIK1 GRIK2

3.17e-0393633GO:0097110
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GRID1 GRID2 GRIK1 GRIK2

3.23e-03193634GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GRID1 GRID2 GRIK1 GRIK2

3.48e-03197634GO:0022834
GeneOntologyMolecularFunctionantioxidant activity

GPX6 GPX3 GPX4

3.57e-0397633GO:0016209
GeneOntologyCellularComponentpostsynaptic density membrane

NPTN ARC GRID1 GRID2 GRIK1 GRIK2

7.08e-06157626GO:0098839
GeneOntologyCellularComponentglutamatergic synapse

NPTN BIN1 SPTBN1 DPYSL5 APC ARC GRID1 GRID2 GRIK1 GRIK2 NRP1

2.50e-058176211GO:0098978
GeneOntologyCellularComponentpostsynaptic specialization membrane

NPTN ARC GRID1 GRID2 GRIK1 GRIK2

2.88e-05201626GO:0099634
GeneOntologyCellularComponentsodium channel complex

GRIK1 GRIK2 UNC80

8.59e-0529623GO:0034706
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIK1 GRIK2

1.29e-046622GO:0032983
GeneOntologyCellularComponentpostsynaptic membrane

NPTN ARC GRID1 GRID2 GRIK1 GRIK2 NRP1

1.91e-04405627GO:0045211
GeneOntologyCellularComponentdendrite

NPTN BIN1 DPYSL5 APC ARC GRID2 GRIK1 OSBP2 GRIK2 OPA1

1.99e-048586210GO:0030425
GeneOntologyCellularComponentdendritic tree

NPTN BIN1 DPYSL5 APC ARC GRID2 GRIK1 OSBP2 GRIK2 OPA1

2.03e-048606210GO:0097447
GeneOntologyCellularComponentspectrin

SPTBN5 SPTBN1

3.07e-049622GO:0008091
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRID2 GRIK1 GRIK2

3.23e-0445623GO:0008328
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

SPTBN5 DNAI1 WDR35 ARC GRIK2 OPA1

3.49e-04317626GO:0032838
GeneOntologyCellularComponentpostsynaptic density

NPTN SPTBN1 ARC GRID1 GRID2 GRIK1 GRIK2

3.67e-04451627GO:0014069
GeneOntologyCellularComponentneurotransmitter receptor complex

GRID2 GRIK1 GRIK2

4.41e-0450623GO:0098878
GeneOntologyCellularComponentasymmetric synapse

NPTN SPTBN1 ARC GRID1 GRID2 GRIK1 GRIK2

5.13e-04477627GO:0032279
GeneOntologyCellularComponentcytoplasmic region

SPTBN5 DNAI1 WDR35 ARC GRIK2 OPA1

6.83e-04360626GO:0099568
GeneOntologyCellularComponentpostsynaptic specialization

NPTN SPTBN1 ARC GRID1 GRID2 GRIK1 GRIK2

7.02e-04503627GO:0099572
GeneOntologyCellularComponentpostsynapse

NPTN BIN1 SPTBN1 APC ARC GRID1 GRID2 GRIK1 GRIK2 NRP1

7.69e-0410186210GO:0098794
GeneOntologyCellularComponentsomatodendritic compartment

NPTN BIN1 DPYSL5 APC ARC GRID2 GRIK1 OSBP2 GRIK2 OPA1 NRP1

8.78e-0412286211GO:0036477
GeneOntologyCellularComponentneuron to neuron synapse

NPTN SPTBN1 ARC GRID1 GRID2 GRIK1 GRIK2

8.82e-04523627GO:0098984
GeneOntologyCellularComponentaxon

BIN1 SPTBN1 APC GRIK1 GRIK2 NDRG2 OPA1 UNC80 NRP1

1.19e-03891629GO:0030424
GeneOntologyCellularComponentsynaptic membrane

NPTN ARC GRID1 GRID2 GRIK1 GRIK2 NRP1

1.65e-03583627GO:0097060
GeneOntologyCellularComponentdistal axon

BIN1 APC GRIK1 GRIK2 NDRG2 NRP1

1.80e-03435626GO:0150034
GeneOntologyCellularComponentM band

SPTBN1 OBSCN

3.81e-0331622GO:0031430
GeneOntologyCellularComponentneuron projection cytoplasm

ARC GRIK2 OPA1

4.28e-03110623GO:0120111
GeneOntologyCellularComponentcell cortex

SPTBN5 SPTBN1 APC GRB2 ARC

4.85e-03371625GO:0005938
GeneOntologyCellularComponentneuron projection terminus

BIN1 APC GRIK1 GRIK2

5.06e-03233624GO:0044306
DomainIontro_rcpt

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624IPR001320
DomainLig_chan-Glu_bd

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624PF10613
DomainIono_rcpt_met

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624IPR001508
DomainGlu/Gly-bd

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624IPR019594
DomainLig_chan-Glu_bd

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624SM00918
DomainLig_chan

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624PF00060
DomainPBPe

GRID1 GRID2 GRIK1 GRIK2

3.25e-0718624SM00079
DomainGPX_AS

GPX6 GPX3 GPX4

1.21e-067623IPR029759
DomainGLUTATHIONE_PEROXID_2

GPX6 GPX3 GPX4

1.93e-068623PS00763
DomainGLUTATHIONE_PEROXID_1

GPX6 GPX3 GPX4

1.93e-068623PS00460
DomainGlutathione_peroxidase

GPX6 GPX3 GPX4

1.93e-068623IPR000889
DomainGLUTATHIONE_PEROXID_3

GPX6 GPX3 GPX4

1.93e-068623PS51355
DomainGPX_CS

GPX6 GPX3 GPX4

1.93e-068623IPR029760
DomainGSHPx

GPX6 GPX3 GPX4

1.93e-068623PF00255
DomainANF_lig-bd_rcpt

GRID1 GRID2 GRIK1 GRIK2

6.70e-0637624IPR001828
DomainANF_receptor

GRID1 GRID2 GRIK1 GRIK2

6.70e-0637624PF01094
DomainPeripla_BP_I

GRID1 GRID2 GRIK1 GRIK2

8.30e-0639624IPR028082
DomainPH_dom-spectrin-type

SPTBN5 SPTBN1

3.85e-049622IPR001605
DomainActinin_actin-bd_CS

SPTBN5 SPTBN1

2.62e-0323622IPR001589
DomainSpectrin

SPTBN5 SPTBN1

2.62e-0323622PF00435
DomainACTININ_2

SPTBN5 SPTBN1

2.62e-0323622PS00020
DomainACTININ_1

SPTBN5 SPTBN1

2.62e-0323622PS00019
DomainSpectrin_repeat

SPTBN5 SPTBN1

4.16e-0329622IPR002017
DomainSpectrin/alpha-actinin

SPTBN5 SPTBN1

5.04e-0332622IPR018159
DomainSPEC

SPTBN5 SPTBN1

5.04e-0332622SM00150
Domain-

CHIA FUCA2

6.01e-03356223.20.20.80
DomainPH

SPTBN5 SPTBN1 OBSCN OSBP2

7.05e-03229624PF00169
DomainGlyco_hydro_catalytic_dom

CHIA FUCA2

7.06e-0338622IPR013781
Domain-

YTHDC2 NDRG2 TG

7.26e-031196233.40.50.1820
PathwayWP_SELENIUM_MICRONUTRIENT_NETWORK

FADS1 GPX6 GPX3 GPX4

1.28e-0623514MM15979
PathwayKEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS

GPX6 GPX3 GPX4

7.21e-0611513M47926
PathwayREACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS

SPTBN1 GRB2 STAT5A

4.15e-0519513M41732
PathwayWP_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS

DMGDH GPX6 GPX3 GPX4

4.20e-0554514MM15848
PathwayWP_FOLIC_ACID_NETWORK

GPX6 GPX3 GPX4

6.54e-0522513MM15955
PathwayWP_TRANSSULFURATION_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS

DMGDH GPX6 GPX3 GPX4

9.84e-0567514M39710
PathwayREACTOME_FLT3_SIGNALING_IN_DISEASE

SPTBN1 GRB2 STAT5A

1.37e-0428513M41724
PathwayREACTOME_STAT5_ACTIVATION

GRB2 STAT5A

2.66e-047512M27953
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

SPTBN5 SPTBN1 GRB2

3.44e-0438513MM14969
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTBN5 SPTBN1

5.67e-0410512MM15112
PathwayREACTOME_STAT5_ACTIVATION_DOWNSTREAM_OF_FLT3_ITD_MUTANTS

GRB2 STAT5A

5.67e-0410512M41731
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK1 GRIK2

5.67e-0410512M10272
PathwayWP_SELENIUM_METABOLISM_SELENOPROTEINS

GPX6 GPX3 GPX4

5.69e-0445513MM15877
Pubmed

HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells.

GPX6 GPX3 GPX4

1.97e-07763315910762
Pubmed

Human immunodeficiency virus type 1 Tat protein impairs selenoglutathione peroxidase expression and activity by a mechanism independent of cellular selenium uptake: consequences on cellular resistance to UV-A radiation.

GPX6 GPX3 GPX4

1.97e-07763311368344
Pubmed

Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice.

GPX6 GPX3 GPX4

3.15e-07863310652368
Pubmed

Glutathione depletion associated with the HIV-1 TAT protein mediates the extracellular appearance of acidic fibroblast growth factor.

GPX6 GPX3 GPX4

4.72e-0796339501919
Pubmed

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

GRID1 GRIK1 GRIK2

4.72e-07963334100982
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRID2 GRIK1 GRIK2

1.60e-061363320859245
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DNAI1 SPTBN1 DPYSL5 OBSCN GRB2 YTHDC2 OPA1 STAT5A

3.20e-0649763836774506
Pubmed

Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.

GRIK1 GRIK2

3.23e-06263212947409
Pubmed

Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.

GRIK1 GRIK2

3.23e-06263215673679
Pubmed

Expression analysis of two cancer-testis genes, FBXO39 and TDRD4, in breast cancer tissues and cell lines.

FBXO39 RNF17

3.23e-06263224377578
Pubmed

Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.

GRIK1 GRIK2

3.23e-06263211182092
Pubmed

Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.

GRIK1 GRIK2

3.23e-06263215928066
Pubmed

Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.

GRIK1 GRIK2

3.23e-06263214724198
Pubmed

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

GRIK1 GRIK2

3.23e-0626328700852
Pubmed

The kainate receptor subunit GluR6 mediates metabotropic regulation of the slow and medium AHP currents in mouse hippocampal neurones.

GRIK1 GRIK2

3.23e-06263215539395
Pubmed

Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants.

GRID1 GRID2

3.23e-06263237944084
Pubmed

RNA editing of human kainate receptor subunits.

GRIK1 GRIK2

3.23e-0626327696618
Pubmed

Q/R site editing controls kainate receptor inhibition by membrane fatty acids.

GRIK1 GRIK2

3.23e-06263216221857
Pubmed

Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.

GRIK1 GRIK2

3.23e-06263216219388
Pubmed

Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

GRIK1 GRIK2

3.23e-0626328260617
Pubmed

Subunit composition and alternative splicing regulate membrane delivery of kainate receptors.

GRIK1 GRIK2

3.23e-06263215014126
Pubmed

Glutathione peroxidases.

GPX6 GPX4

3.23e-06263223201771
Pubmed

Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.

GRIK1 GRIK2

3.23e-06263215537878
Pubmed

Subunit composition of kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

3.23e-06263211144357
Pubmed

Contribution of aberrant GluK2-containing kainate receptors to chronic seizures in temporal lobe epilepsy.

GRIK1 GRIK2

3.23e-06263225043179
Pubmed

Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain.

GRID1 GRID2

3.23e-06263231625608
Pubmed

GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons.

GRID1 GRID2

3.23e-06263228696429
Pubmed

Postnatal maturation of mossy fibre excitatory transmission in mouse CA3 pyramidal cells: a potential role for kainate receptors.

GRIK1 GRIK2

3.23e-06263215358807
Pubmed

Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.

GRIK1 GRIK2

3.23e-06263224760837
Pubmed

A mosaic of functional kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

3.23e-06263215483117
Pubmed

Glutamate receptors of the delta family are widely expressed in the adult brain.

GRID1 GRID2

3.23e-06263225001082
Pubmed

Functional characterization of kainate receptors in the mouse nucleus accumbens.

GRIK1 GRIK2

3.23e-06263211985817
Pubmed

Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus.

GRIK1 GRIK2

3.23e-06263211069933
Pubmed

Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.

BIN1 GRB2

9.68e-0636329736607
Pubmed

Postsynaptic density-93 interacts with the delta2 glutamate receptor subunit at parallel fiber synapses.

GRID1 GRID2

9.68e-06363210234023
Pubmed

Distinct roles for the kainate receptor subunits GluR5 and GluR6 in kainate-induced hippocampal gamma oscillations.

GRIK1 GRIK2

9.68e-06363215509753
Pubmed

Differential expression and distribution of placental glutathione peroxidases 1, 3 and 4 in normal and preeclamptic pregnancy.

GPX3 GPX4

9.68e-06363220303587
Pubmed

Identification of rat EMAP, a delta-glutamate receptor binding protein.

GRID1 GRID2

9.68e-06363211829466
Pubmed

Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor.

GRIK1 GRIK2

9.68e-06363227346345
Pubmed

Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate receptor channel.

GRIK1 GRIK2

9.68e-0636321379666
Pubmed

Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors.

GRIK1 GRIK2

9.68e-0636328730589
Pubmed

Glutathione peroxidase activity and expression levels are significantly increased in acute coronary syndromes.

GPX3 GPX4

9.68e-06363228298473
Pubmed

Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice.

GRIK1 GRIK2

9.68e-0636329880586
Pubmed

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.

GRIK1 GRIK2

9.68e-06363231513786
Pubmed

Differential trafficking of GluR7 kainate receptor subunit splice variants.

GRIK1 GRIK2

9.68e-06363215805114
Pubmed

Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.

STAT5A NRP1

9.68e-06363225231404
Pubmed

Aberrant expression of selenium-containing glutathione peroxidases in clear cell renal cell carcinomas.

GPX3 GPX4

9.68e-06363226112936
Pubmed

RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue.

GRIK1 GRIK2

9.68e-0636327523595
Pubmed

The human glutathione peroxidase genes GPX2, GPX3, and GPX4 map to chromosomes 14, 5, and 19, respectively.

GPX3 GPX4

9.68e-0636328287691
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

SPTBN5 SPTBN1 GRB2

1.27e-05256338493579
Pubmed

Genetic evidence for the requirement of adenylyl cyclase 1 in synaptic scaling of forebrain cortical neurons.

GRIK1 GRIK2

1.93e-05463217650106
Pubmed

The auxiliary subunits Neto1 and Neto2 have distinct, subunit-dependent effects at recombinant GluK1- and GluK2-containing kainate receptors.

GRIK1 GRIK2

1.93e-05463226277340
Pubmed

Enriched expression of GluD1 in higher brain regions and its involvement in parallel fiber-interneuron synapse formation in the cerebellum.

GRID1 GRID2

1.93e-05463224872547
Pubmed

The murine Bin1 gene functions early in myogenesis and defines a new region of synteny between mouse chromosome 18 and human chromosome 2.

BIN1 APC

1.93e-05463210036185
Pubmed

Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses.

GRIK1 GRIK2

1.93e-05463216354929
Pubmed

Coexistence of two forms of LTP in ACC provides a synaptic mechanism for the interactions between anxiety and chronic pain.

GRIK1 GRIK2

1.93e-05463225556835
Pubmed

Kainate receptors and rhythmic activity in neuronal networks: hippocampal gamma oscillations as a tool.

GRIK1 GRIK2

1.93e-05463215513934
Pubmed

Synaptic activation of kainate receptors gates presynaptic CB(1) signaling at GABAergic synapses.

GRIK1 GRIK2

1.93e-05463220081851
Pubmed

Involvement of Fes/Fps tyrosine kinase in semaphorin3A signaling.

DPYSL5 NRP1

1.93e-05463212093729
Pubmed

Structural basis for integration of GluD receptors within synaptic organizer complexes.

GRID1 GRID2

1.93e-05463227418511
Pubmed

Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice.

GRIK1 GRIK2

1.93e-05463230241548
Pubmed

Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice.

DMGDH ARC

1.93e-05463218782777
Pubmed

Sex-specific perinatal expression of glutathione peroxidases during mouse lung development.

GPX3 GPX4

1.93e-05463222326323
Pubmed

Kainate receptors act as conditional amplifiers of spike transmission at hippocampal mossy fiber synapses.

GRIK1 GRIK2

1.93e-05463219369569
Pubmed

Simultaneous genotyping of 11 non-synonymous SNPs in the 4 glutathione peroxidase genes using the multiplex single base extension method.

GPX3 GPX4

1.93e-05463219161995
Pubmed

Localization of glutamate receptors to distal dendrites depends on subunit composition and the kinesin motor protein KIF17.

GRIK1 GRIK2

1.93e-05463217174564
Pubmed

Developmental expression patterns of kainate receptors in the mouse spinal cord.

GRIK1 GRIK2

3.22e-05563223076118
Pubmed

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

GRIK1 GRIK2

3.22e-05563228228252
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIK1 GRIK2

3.22e-0556321717158
Pubmed

Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.

GRIK1 GRIK2

3.22e-0556329593973
Pubmed

Kainate receptors: pharmacology, function and therapeutic potential.

GRIK1 GRIK2

3.22e-05563218793656
Pubmed

Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.

GRIK1 GRIK2

3.22e-05563212223554
Pubmed

Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors.

GRID2 GRIK2

3.22e-05563212573530
Pubmed

KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer.

APC IRF2

3.22e-05563230905761
Pubmed

Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition.

GRIK1 GRIK2

3.22e-05563228854365
Pubmed

Neuropilin-1 expression in cancer and development.

APC NRP1

3.22e-05563222025255
Pubmed

Molecular determinants of kainate receptor trafficking.

GRIK1 GRIK2

3.22e-05563218358623
Pubmed

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.

GRIK1 GRIK2

3.22e-05563229058671
Pubmed

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.

DNAI1 APC

4.82e-05663228057765
Pubmed

Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma.

GPX3 GPX4

4.82e-05663218483336
Pubmed

Neto1 is an auxiliary subunit of native synaptic kainate receptors.

GRIK1 GRIK2

4.82e-05663221734292
Pubmed

Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP.

GRIK1 GRIK2

4.82e-05663212597860
Pubmed

Ubiquitin binds to and regulates a subset of SH3 domains.

BIN1 GRB2

4.82e-05663217244534
Pubmed

N-glycan content modulates kainate receptor functional properties.

GRIK1 GRIK2

4.82e-05663228714086
Pubmed

The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins.

BIN1 GRB2

4.82e-05663218647389
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

UTP6 SPNS1 TRIM28 GPX4 DPYSL5 GEMIN4 GRB2 YTHDC2 OPA1

6.23e-0597463928675297
Pubmed

Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin.

BIN1 GRB2

6.74e-05763212558988
Pubmed

Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses.

GRIK1 GRIK2

6.74e-05763217428973
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIK1 GRIK2

6.74e-0576329016303
Pubmed

Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis.

GRIK1 GRIK2

6.74e-05763219342380
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIK1 GRIK2

6.74e-0576329651535
Pubmed

Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

GRIK1 GRIK2

6.74e-0576321310861
Pubmed

Association of STAT1, STAT3 and STAT5 proteins with the IL-2 receptor involves different subdomains of the IL-2 receptor beta chain.

GRB2 STAT5A

8.98e-05863210602027
Pubmed

Expression and regulation of antioxidant enzymes in the developing limb support a function of ROS in interdigital cell death.

GPX3 GPX4

8.98e-05863216445905
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIK1 GRIK2

8.98e-0586328163463
Pubmed

GluD1 is a signal transduction device disguised as an ionotropic receptor.

GRID1 GRID2

8.98e-05863234135511
Pubmed

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.

GRID1 GRID2

1.15e-04963212372286
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIK1 GRIK2

1.15e-0496329051806
Pubmed

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

FADS1 DPYSL5 KDM2B

1.39e-045563322581228
Pubmed

USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells.

SPTBN1 NRP1

1.44e-041063236653359
InteractionGRIK5 interactions

TRIM28 GRID2 GRIK1 GRIK2

3.79e-0720624int:GRIK5
Cytoband10q22

NDST2 GRID1

2.80e-041863210q22
GeneFamilyGlutamate ionotropic receptor delta type subunits

GRID1 GRID2

5.27e-0624221202
GeneFamilySelenoproteins

GPX6 GPX3 GPX4

2.59e-0525423890
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK1 GRIK2

5.24e-0554221199
GeneFamilyEF-hand domain containing|Spectrins

SPTBN5 SPTBN1

1.10e-0474221113
CoexpressionLANDIS_ERBB2_BREAST_TUMORS_324_DN

FADS1 FCGBP SPTBN1 GPX3 SOWAHC NRP1

1.71e-06151636M8901
CoexpressionLANDIS_ERBB2_BREAST_TUMORS_324_DN

FADS1 FCGBP SPTBN1 GPX3 SOWAHC NRP1

2.15e-06157636MM1099
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRID2 GRIK1 GRIK2 ADCYAP1R1

2.65e-0718763685f1678338a47d91e296f0620d4887f057eb7e70
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRID2 GRIK1 GRIK2 ADCYAP1R1

3.20e-07193636d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRID2 GRIK1 GRIK2 ADCYAP1R1

3.20e-07193636e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPNS1 BIN1 FCGBP CD300A GRB2 NRP1

3.94e-072006365f1de1f9305e1784c12d526f6c8bdd7d56229f9b
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC41A2 GPX3 OBSCN FUCA2 TMPRSS7

3.38e-06162635ca1014e32996f777bff021830ce9a7cf4acf58d5
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Brain / Location, Cell class and cell subclass

FCGBP CD300A C20orf144 NDRG2 UNC80

5.65e-0618063551727cb66fe7a7709453f7026e0ff3d6c93d5aa5
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC41A2 NPTN OBSCN APC NRP1

5.65e-06180635bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC41A2 NPTN OBSCN APC NRP1

5.65e-06180635839defb40f7cfb2711e9025194de636533f51bcd
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC41A2 NPTN OBSCN APC NRP1

5.65e-0618063582965ed1b72a1873c24dd4553d39681596057316
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 GRID2 GRIK1 GRIK2 ADCYAP1R1

6.45e-06185635ae53aa2ecfe418a5dbd7d963a995bc06dab94f56
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ADAMTS20 GRIK1 GRIK2 UNC80

6.80e-06187635a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ADAMTS20 GRIK1 GRIK2 UNC80

6.80e-06187635f2af79a20438108c814a73f9e24cd986d537237f
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 GRIK1 GRIK2 NDRG2 UNC80

6.97e-061886358385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS20 GRIK1 GRIK2 NDRG2 UNC80

6.97e-06188635cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FADS1 GPX3 PAPPA GRID1 GRID2

7.34e-0619063545df8fee00f8949937863159d7aa042e72748d9b
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL5 GRIK1 GRIK2 NDRG2 UNC80

7.34e-06190635e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRIK1 GRIK2 ADCYAP1R1

7.92e-06193635010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRID2 GRIK1 GRIK2

7.92e-061936358b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPPA GRID2 GRIK1 GRIK2 ADCYAP1R1

7.92e-061936353ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPPA GRID2 GRIK1 GRIK2 ADCYAP1R1

7.92e-06193635658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

LEFTY2 SPTBN1 GPX3 NDRG2 NRP1

8.75e-0619763544f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-NPM1P10|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADAMTS20 GRID2 GRIK1 GRIK2 ADCYAP1R1

9.41e-062006357b3284bf0000e14f5a51e4422231e5639a184579
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-NPM1P10-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADAMTS20 GRID2 GRIK1 GRIK2 ADCYAP1R1

9.41e-06200635e957f5926675f6c29208cfc3203a19dab538df38
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

PAPPA GRID2 GRIK1 GRIK2 ADCYAP1R1

9.41e-06200635347a510755374c6a66acee326565dfc447993f18
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-NPM1P10--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADAMTS20 GRID2 GRIK1 GRIK2 ADCYAP1R1

9.41e-062006352ea33ac1970791e6a601ac1e407ef32e4833792d
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

ADAMTS20 PAPPA GRIK1 GRIK2 ADCYAP1R1

9.41e-06200635107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 OBSCN ARC NRP1

3.91e-051346346d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCellfacs-Thymus-nan-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ADAMTS20 C20orf144 STEAP1

4.64e-05140634115bd770a9d5e6f007a9aa0eadf5dba46d500107
ToppCellfacs-Thymus-nan-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ADAMTS20 C20orf144 STEAP1

4.64e-0514063422d126e80bf7d9c0ca6ec686b5cc66fa584a1ab6
ToppCellfacs-Thymus-nan-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ADAMTS20 C20orf144 STEAP1

4.64e-0514063462d1ef8cb78618ed89cac7ec89d7f54de06a90c7
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LPIN3 GPX3 ADTRP NDRG2

6.72e-0515463444d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 OBSCN ARC NRP1

7.06e-05156634fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCellControl-B_naive-12|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DMGDH NPTN WDR35 APC

7.24e-051576344803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCellControl-B_naive-12|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DMGDH NPTN WDR35 APC

7.42e-0515863441318f864770370ce77ed3fa4a84f76c0c22c482
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 GPX6 GRIK2 UNC80

7.79e-05160634c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 GPX6 GRIK2 UNC80

7.79e-0516063425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 OBSCN ARC NRP1

8.37e-05163634b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH SEC16B FADS1 ADTRP

8.57e-0516463490afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD300A ADAMTS20 UNC80 ADCYAP1R1

8.78e-05165634b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)-Glut_ET_L5_FEZF2-Exc_L3-5_FEZF2_DCN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DNAI1 FBXO39 ADTRP NRP1

8.78e-05165634aad0ab96d9d4387edfcef2b114346a030eb4b021
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD300A ADAMTS20 UNC80 ADCYAP1R1

8.78e-0516563428f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CD300A GPX3 GPX4 ADAMTS20

8.78e-051656347fe24be5bae7f0344243fb06cdfa02b4ddbb5a19
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH FADS1 ADTRP NDRG2

8.98e-051666344b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH FADS1 ADTRP NDRG2

8.98e-05166634d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS20 GRID2 NDRG2 UNC80

1.03e-041726348d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

FCGBP C20orf144 NDRG2 UNC80

1.03e-0417263438d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCellDendritic_Cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

PLB1 FCGBP CD300A NDRG2

1.10e-04175634584290a51f9975782a5ac8c6ad67c778d8323f8c
ToppCellfacs-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC198 GPX3 GPX4 ADTRP

1.15e-041776347f58286fc8797e9bdcf8ece0849f55680905955d
ToppCellfacs-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH GPX3 GPX4 ADTRP

1.15e-04177634d4cd54c07f1e51b5485270348fb7195d53465027
ToppCellDendritic_Cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SLC41A2 FCGBP CD300A NDRG2

1.18e-041786343a28103cf282cc3637d1875a3b4cd7ddf3207687
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAI1 OBSCN PAPPA GRID1

1.20e-04179634a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCelldroplet-Kidney-nan-21m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC198 GPX6 GPX3 GPX4

1.23e-041806342b2c656d6620afa32555f14aad94ac56e71e360c
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIK1 NDRG2 STEAP1 NRP1

1.25e-04181634e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCellMesenchymal_cells-Adipo-CAR|Mesenchymal_cells / Lineage and Cell class

GPX3 PAPPA STAT5A NRP1

1.25e-041816341cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GMDS NDRG2 STEAP1

1.28e-041826346d7ba2e1f33aaa499a898ed9587197c0ee625e9a
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCGBP NUDCD1 RNF17 NDRG2

1.31e-04183634bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA CCDC198 GPX6 NDRG2

1.31e-0418363403c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCGBP NUDCD1 RNF17 NDRG2

1.31e-04183634d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

SEC16B BIN1 CCDC198 NRP1

1.34e-0418463451ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ADAMTS20 GRID1 UNC80

1.34e-041846342cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ADAMTS20 GRID1 UNC80

1.34e-04184634ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellSerous|World / shred by cell class for bronchial biopsy

FCGBP GPX3 NDRG2 UNC80

1.34e-0418463409d0d1525c11dd326efd942684c03f79d992cf3b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ADAMTS20 GRID1 UNC80

1.34e-041846342b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 CHIA FCGBP ARC

1.34e-041846347cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 CHIA FCGBP ARC

1.34e-0418463453b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellfacs-Heart-LV-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC125 FCGBP ADTRP STEAP1

1.36e-04185634a835f821a5e6568d648df831ec4c2d0048d67093
ToppCellfacs-Heart-LV-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC125 FCGBP ADTRP STEAP1

1.36e-04185634386b08bcb304db543e3c5ff75f85e99bf0c592df
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC198 GPX6 DPYSL5 NDRG2

1.36e-04185634af86e75096c1812ae27a78405355957ee8043d84
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH GRIK1 GRIK2 UNC80

1.39e-04186634ea936e66ae4b7b40564711fad60ac0137327995f
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRID2 ADTRP ADCYAP1R1 NRP1

1.39e-0418663432af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC198 GMDS PAPPA NRP1

1.39e-04186634b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellCF-Lymphoid-pDC|Lymphoid / Disease state, Lineage and Cell class

SLC41A2 FADS1 CD300A NRP1

1.42e-04187634adc79e5804ab98006dbdf1d76ef0d8f85cc5cb0f
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPX3 OBSCN GRID1 ADCYAP1R1

1.45e-04188634ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

FADS1 FCGBP CD300A NDRG2

1.45e-041886345d12afb483d028ca02b3b4215131f6128e8bcd48
ToppCellDendritic_Cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PLB1 FCGBP CD300A NDRG2

1.54e-04191634b51c8ff1279581088557bb36760c70209c77148c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRIK1 ADCYAP1R1

1.54e-041916349c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|(1)_Control_(PBS) / Stress and Cell class

NPTN GPX3 FUCA2 NDRG2

1.57e-0419263440f380f5f0bed63a7404be050838ebd01ef08987
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPPA GRIK1 GRIK2 ADCYAP1R1

1.57e-04192634dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GMDS NDRG2 UNC80

1.57e-0419263448b69d6f46e583378186d2993a202f9584688bfa
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPPA GRIK1 GRIK2 ADCYAP1R1

1.60e-041936342189da4b727e25e62669d7b9257f06493be21a27
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GMDS NDRG2 UNC80

1.60e-0419363456145861ef5e7655db9ad0d11b82f72dcadf285d
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GMDS NDRG2 UNC80

1.60e-041936343d1710a6060d3a70994a206334ccb16cd63e5f20
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid|TCGA-Endometrium / Sample_Type by Project: Shred V9

CCDC125 GPX4 GMDS STEAP1

1.60e-041936343465352298b1fc9d75af4c2fdd91ad7990cbc901
ToppCellCOPD-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

FCGBP GPX3 GMDS NDRG2

1.64e-0419463472a2e0cba171ab59aa176e91a59a54c562af0390
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-DC2|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC41A2 BIN1 PLB1 NDRG2

1.64e-04194634a0cfc8c1cdc0722db39170e4417615b6e6b85041
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS20 PAPPA GRIK1 ADCYAP1R1

1.64e-04194634e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAPPA GRID2 GRIK1 GRIK2

1.64e-041946341bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP GMDS NDRG2 UNC80

1.64e-04194634a8238f312a973cadf6eb29c1e02ba898c0a20412
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DMGDH OBSCN ADTRP

1.64e-04756333dac715d3610f3bfa6e65e607562d6560462749e
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DMGDH OBSCN ADTRP

1.64e-04756338a0568fca07cf5d1016a04bcc3ba365dd5e53f7a
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DMGDH OBSCN ADTRP

1.64e-0475633fc508ffa30ec364949b82b8271b8dc4e67b6a416
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DMGDH OBSCN ADTRP

1.64e-0475633324d34ae723a462052074f6a2e4f5d21c4c4c00d
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAI1 BIN1 DPYSL5 NRP1

1.67e-041956347e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellmedial-Endothelial-Capillary_Intermediate_2-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAOA SPTBN1 GPX3 NDRG2

1.70e-041966345cc14a5797884ff3a007683048e690a0d7172fc4
ToppCellmedial-Endothelial-Capillary_Intermediate_2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAOA SPTBN1 GPX3 NDRG2

1.70e-0419663407e6214e771c65574f0ada65e75f4bda265aa47f
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FCGBP CD300A GPX4 NRP1

1.70e-0419663488517bb92be2f05c1e1ad94af22ac10d8c5c13c7
ToppCellmedial-2-Endothelial-Capillary_Intermediate_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAOA SPTBN1 GPX3 NDRG2

1.70e-04196634d074c24fecd0e3ffca4699fb1a9d443e6d9a858d
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

MAOA SPTBN1 GPX3 NRP1

1.74e-04197634156155c2f0c1a2461e45803da578af18ee221660
ToppCellSepsis-ICU-SEP-Myeloid-cDC1|ICU-SEP / Disease, condition lineage and cell class

LPIN3 SLC41A2 NUDCD1 NDRG2

1.74e-04197634e3174e90ea6136f1aa3a4a185b86458e35d51fd4
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPX3 OBSCN GRID1 ADCYAP1R1

1.74e-04197634f66945f9007d59d4208849c7fd727f8519713fbc
DrugL-BMAA

GRID1 GRID2 GRIK1 GRIK2

3.66e-0638634CID000028558
DrugDETC-MeSO

GRID1 GRID2 GRIK1 GRIK2

4.07e-0639634CID003035711
DrugHA-966

SPNS1 GRID1 GRID2 GRIK1

4.07e-0639634CID000001232
DrugJoro spider toxin

GRID1 GRID2 GRIK1 GRIK2

6.06e-0643634CID000119582
Drug5-nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime

GRIK1 GRIK2

7.54e-062632ctd:C084273
Drug5,7-dichlorokynurenic acid

SPNS1 GRID1 GRID2 GRIK1

1.03e-0549634CID000001779
DrugLY354740

GRID1 GRID2 GRIK1 GRIK2

1.21e-0551634CID000114827
DrugNorgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A

SPTBN1 ARC OSBP2 RNF17 NDRG2 NRP1

1.56e-051936363708_UP
DrugCyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A

SPTBN5 BIN1 SPTBN1 APC ARC NDRG2

1.65e-051956363268_UP
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

SPTBN5 BIN1 MAOA APC OSBP2 ADTRP

1.75e-051976364729_UP
DrugBumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A

SPTBN5 BIN1 SPTBN1 APC ADTRP RNF17

1.86e-051996365542_UP
DrugGYKI 52466

GRID1 GRID2 GRIK1 GRIK2

2.02e-0558634CID000003538
DrugYM90K

GRID1 GRID2 GRIK1

3.44e-0523633CID005486547
DrugL-Glutamic Acid

GRID1 GRID2 GRIK1 GRIK2

3.80e-0568634DB00142
DrugCGP 39653

GRID1 GRID2 GRIK1

3.92e-0524633CID006437837
Drugfelbamate

GRID1 GRID2 GRIK1 GRIK2

4.26e-0570634CID000003331
Druggavestinel

GRID1 GRID2 GRIK1

4.45e-0525633CID006450546
DrugAC1L1DME

GRID1 GRID2 GRIK1 GRIK2

5.58e-0575634CID000002414
DrugL-689,560

GRID1 GRID2 GRIK1

5.63e-0527633CID000121918
Drugaptiganel

GRID1 GRID2 GRIK1

6.30e-0528633CID000060839
DrugC-PP

GRID1 GRID2 GRIK1

6.30e-0528633CID000001228
DrugAC1NUW3V

GRID1 GRID2 GRIK1

7.01e-0529633CID005462126
Drugketobemidone

GRID1 GRID2 GRIK1

7.01e-0529633CID000010101
Drugcis-2,3-piperidine dicarboxylic acid

GRID1 GRID2 GRIK1

7.77e-0530633CID000001226
DrugAC1L32TU

GRID1 GRID2 GRIK1

7.77e-0530633CID000107831
DrugGYKI 53655

GRID1 GRID2 GRIK1

7.77e-0530633CID000126757
Druguranyl acetate

TRIM28 DPYSL5 APC GRB2 KDM2B NDRG2

7.90e-05258636ctd:C005460
DrugLY235959

GRID1 GRID2 GRIK1

8.59e-0531633CID000131938
DrugNPC 12626

GRID1 GRID2 GRIK1

8.59e-0531633CID000108099
Drugeliprodil

GRID1 GRID2 GRIK1

8.59e-0531633CID000060703
Drugalpha-methyl-4-carboxyphenylglycine

GRID1 GRID2 GRIK1

9.46e-0532633CID000001222
Drugmemantine

GRID1 GRID2 GRIK1 OPA1

9.54e-0586634CID000004054
Drug1-aminoindan-1,5-dicarboxylic acid

GRID1 GRID2 GRIK1

1.04e-0433633CID000002071
Drugwyosine

TYW1 TG

1.12e-046632CID000171185
DrugD-CPPene

GRID1 GRID2 GRIK1

1.14e-0434633CID006435801
DrugN-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid

GRID1 GRID2 GRIK1

1.24e-0435633ctd:C520612
DrugGlutathione

GPX6 GPX3 GPX4

1.35e-0436633DB00143
Druggacyclidine

GRID1 GRID2 GRIK1

1.35e-0436633CID000176265
DrugR,S)-AMPA

GRID1 GRID2 GRIK1

1.35e-0436633CID000001221
DrugC6H12NO5P

GRID1 GRID2 GRIK1

1.35e-0436633CID000104962
Drugglutamic acid diethyl ester

GRID1 GRID2 GRIK1

1.35e-0436633CID000073960
DrugCGS 19755

GRID1 GRID2 GRIK1

1.59e-0438633CID000068736
Drug4CPG

GRID1 GRID2 GRIK1

1.59e-0438633CID000005115
DrugUranium

TRIM28 DPYSL5 APC GRB2 KDM2B NDRG2

1.67e-04296636ctd:D014501
DrugPyridostigmine Bromide

GPX6 GPX3 GPX4 APC

1.71e-04100634ctd:D011729
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

SPTBN5 BIN1 CHIA MAOA APC

1.91e-041926355567_UP
Drugcyclothiazide

GRID1 GRID2 GRIK1 GRIK2

1.92e-04103634CID000002910
DrugFusaric acid [536-69-6]; Up 200; 22.4uM; MCF7; HT_HG-U133A

BIN1 ARC IRF2 YTHDC2 NDRG2

2.01e-041946353245_UP
Drug4-nitrophenyl-N-acetyl-beta-D-glucosaminide

CHIA FUCA2

2.09e-048632CID000082398
DrugRiluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A

SPTBN5 APC ARC ADTRP NDRG2

2.11e-041966352295_UP
DrugNitrofurantoin [67-20-9]; Down 200; 16.8uM; MCF7; HT_HG-U133A

BIN1 MAOA NDST2 APC ARC

2.11e-041966354697_DN
DrugBucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; HL60; HT_HG-U133A

BIN1 CCDC198 MAOA GRIK2 NRP1

2.11e-041966352741_UP
DrugTetramisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A

SPTBN5 MAOA SPTBN1 YTHDC2 ADTRP

2.16e-041976354587_UP
DrugLidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A

BIN1 SPTBN1 APC ARC NDRG2

2.21e-041986351499_UP
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; PC3; HT_HG-U133A

ARC YTHDC2 OSBP2 RNF17 NRP1

2.21e-041986353743_UP
Drugaspirin, USP; Up 200; 100uM; PC3; HT_HG-U133A

PAPPA GRIK2 RNF17 NDRG2 STAT5A

2.21e-041986354428_UP
Drugracemethorphan

MAOA GRID1 GRID2 GRIK1

2.22e-04107634CID000003008
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

SPTBN5 BIN1 APC ARC RNF17

2.26e-041996352329_UP
DrugMolsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A

BIN1 ARC IRF2 ADTRP RNF17

2.26e-041996355426_UP
DrugDibucaine [85-79-0]; Down 200; 11.6uM; PC3; HG-U133A

BIN1 MAOA GEMIN4 APC OPA1

2.26e-041996351889_DN
Drugkynurenine

BIN1 GRID1 GRID2 GRIK1

2.30e-04108634CID000000846
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

CCDC198 APC ARC RNF17 NDRG2

2.31e-042006355601_UP
Drugwortmannin; Up 200; 0.01uM; SKMEL5; HG-U133A

BIN1 MAOA ADTRP NDRG2 TG

2.31e-04200635506_UP
Drug7-chlorokynurenic acid

GRID1 GRID2 GRIK1

2.64e-0445633CID000001884
Drug1m5b

GRIK1 GRIK2

2.68e-049632CID000447081
DrugLY339434

GRIK1 GRIK2

2.68e-049632CID006324635
Drugferrous oxalate dihydrate

GMDS OPA1

2.68e-049632CID000516788
DiseaseSchizophrenia

NPTN MAOA APC GRB2 ARC KDM2B GRID1 GRIK1 GRIK2 OPA1 ADCYAP1R1

1.73e-068836111C0036341
Diseasebody mass index, fasting blood glucose measurement

FADS1 DPYSL5 KDM2B

1.63e-0451613EFO_0004340, EFO_0004465
DiseaseColorectal Neoplasms

FADS1 TRIM28 GPX4 APC GRID1

2.72e-04277615C0009404
DiseaseEndometrioma

MAOA GPX3 PAPPA NRP1

3.50e-04161614C0269102
DiseaseEndometriosis

MAOA GPX3 PAPPA NRP1

3.50e-04161614C0014175
Diseaseeicosapentaenoate EPA; 20:5n3 measurement

FADS1 GRIK2

5.60e-0417612EFO_0021049
DiseaseColorectal Carcinoma

FADS1 TRIM28 GPX4 OBSCN APC GRID1 GRID2

5.99e-04702617C0009402
Diseaseprostate adenocarcinoma (is_implicated_in)

BIN1 GRB2

7.80e-0420612DOID:2526 (is_implicated_in)
Diseasebrain measurement, neuroimaging measurement

SPTBN1 DPYSL5 ADAMTS20 PAPPA NRP1 TG

9.51e-04550616EFO_0004346, EFO_0004464
Diseasephosphatidylserines measurement

FADS1 GRIK2

1.03e-0323612EFO_0020049
Diseaseceramide measurement

SEC16B FADS1 GPX4 OSBP2

1.43e-03235614EFO_0010222
Diseasegastric adenocarcinoma (is_marker_for)

GPX4 STAT5A

1.53e-0328612DOID:3717 (is_marker_for)
Diseaseneuroimaging measurement

FADS1 SPTBN1 DPYSL5 APC ADAMTS20 PAPPA NRP1 TG

1.55e-031069618EFO_0004346
DiseaseCarcinoma, Granular Cell

GPX3 APC STAT5A

1.80e-03116613C0205644
DiseaseAdenocarcinoma, Tubular

GPX3 APC STAT5A

1.80e-03116613C0205645
DiseaseAdenocarcinoma, Oxyphilic

GPX3 APC STAT5A

1.80e-03116613C0205642
DiseaseCarcinoma, Cribriform

GPX3 APC STAT5A

1.80e-03116613C0205643
DiseaseAdenocarcinoma, Basal Cell

GPX3 APC STAT5A

1.80e-03116613C0205641
DiseaseAdenocarcinoma

GPX3 APC STAT5A

1.80e-03116613C0001418

Protein segments in the cluster

PeptideGeneStartEntry
QIQNHMNGPAKKWWE

ARC

241

Q7LC44
LHMMKEKWWRGNGCP

GRIK1

806

P39086
WEPMKVHDIRWNFEK

GPX3

171

P22352
GEKLNHWKWGDMRQP

ADTRP

211

Q96IZ2
AQWLKHNKFGGAMVW

CHIA

346

Q9BZP6
HSDPVWQVKWQKDDM

DNAI1

431

Q9UI46
KKMAQWRHGSWTPCS

ADAMTS20

1151

P59510
IPWMHAARHGWDVEK

IRF2

36

P14316
WQPHSSKQDDMWEHI

NUDCD1

466

Q96RS6
DAPWEAQHADKWDKM

MAOA

141

P21397
ESHMQWAWGRLPKVA

LPIN3

241

Q9BQK8
KRDWGHAKDYVEAMW

GMDS

246

O60547
DMDILKHKWWPKNGQ

GRID2

796

O43424
HDPHGQVIWGMSWAK

FBXO39

261

Q8N4B4
AGVATWPWDKEALMH

PAPPA

526

Q13219
MDNSDPNWWKGACHG

GRB2

186

P62993
WEAKEKQDWHMCPNI

OSBP2

901

Q969R2
GMWDNITCWKPAHVG

ADCYAP1R1

56

P41586
KMAPVEWWKGHETLR

OBSCN

3651

Q5VST9
LVWMAIGHQGDHWKE

NRP1

751

O14786
NAIENMVGPDWKKRW

OPA1

761

O60313
HQMPCKWGWALALTN

FUCA2

451

Q9BTY2
VDWVDNMWPQHLKEK

KDM2B

196

Q8NHM5
KWMNWKHLKEDGFPS

CCDC125

356

Q86Z20
NDWHDSQEKPAMEKW

FCGBP

5381

Q9Y6R7
PADMDKAWWKSFLNH

C20orf144

21

Q9BQM9
IGHLKGAPASWWNHM

FADS1

201

O60427
DLQGMKWAKNWVLEP

LEFTY2

271

O00292
KCSMGFHAGWEQPHW

DMGDH

481

Q9UI17
DLDVLKQKWWPHMGR

GRID1

796

Q9ULK0
KQKWWPHMGRCDLTS

GRID1

801

Q9ULK0
MSHWAPEWKRAEANP

DDX53

1

Q86TM3
LHMMKEKWWRGNGCP

GRIK2

791

Q13002
NGDDAHPLWKWMKIQ

GPX4

136

P36969
WEPMKVHDIRWNFEK

GPX6

171

P59796
KPMWEDDANKNGGKW

EIF4E2

121

O60573
GWLMGVKESDWNQHK

BIN1

561

O00499
CPWKIGKMETWLHEQ

CCDC198

236

Q9NVL8
HVGITWWAPKVKAEM

DPYSL5

131

Q9BPU6
IHSNKPALWIMAAKW

UTP6

136

Q9NYH9
IDPNAKGWMDWAAHK

NDRG2

171

Q9UN36
KGWMDWAAHKLTGLT

NDRG2

176

Q9UN36
DWMVHHFWRKGKDPD

SLC41A2

521

Q96JW4
PLEHAWMLSASDGKW

SOWAHC

266

Q53LP3
WHLWNRMMEPAGEKD

PLB1

306

Q6P1J6
WKHKMLEWDLEVQAG

SPTBN5

2616

Q9NRC6
ALDTGWNELHKMWEN

SPTBN1

1146

Q01082
PHWLDKWMLTRKQFG

STEAP1

151

Q9UHE8
WQWFDGVMEVLKKHH

STAT5A

571

P42229
WEWQEAHEPGMDQDK

APC

421

P25054
WRMFQKWIKAGDHSE

CD300A

201

Q9UGN4
SKWEPVKWENDMHCA

RNF17

956

Q9BXT8
NWPEWMKGHHVNITK

UNC80

1236

Q8N2C7
KSMKGCEHGWWEINE

TMPRSS7

421

Q7RTY8
GSKVKDMAGDWHWAL

SPNS1

206

Q9H2V7
HPDWIWRKKENGMPM

NPTN

266

Q9Y639
AGDDMLLKHRKEFWW

NDST2

371

P52849
EALEWAMKNHLWGHA

SEC16B

456

Q96JE7
KASNGWMALDWAKHF

YTHDC2

536

Q9H6S0
VGKNVDKWLWMLGAH

TYW1

191

Q9NV66
VWDMKWAKDNPDLFA

WDR35

596

Q9P2L0
MGSTKHWGEWLLNLK

PIGM

1

Q9H3S5
NVKDWMDPSEAWANA

TG

1761

P01266
HGEMKFQWDLNAWTK

TRIM28

386

Q13263
LDVWWEVMKHKGHPQ

GEMIN4

161

P57678