Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionunfolded protein binding

UGGT1 AFG3L2

5.83e-0412662GO:0051082
GeneOntologyBiologicalProcessresponse to endoplasmic reticulum stress

UGGT1 TMEM117

2.94e-0329562GO:0034976
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

AFG3L2 NIPAL4

2.11e-0268152MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

AFG3L2 NIPAL4

2.45e-0273652M27287
Pubmed

Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

AFG3L2 PTDSS1

1.56e-041136230352685
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

UGGT1 AFG3L2 PTDSS1

1.72e-047256327025967
CoexpressionGSE13485_DAY3_VS_DAY7_YF17D_VACCINE_PBMC_UP

UGGT1 AFG3L2 PTDSS1

7.15e-0618863M3300
CoexpressionGSE14308_TH2_VS_TH17_UP

ELMOD2 UGGT1 AFG3L2

8.61e-0620063M3361
CoexpressionGSE42724_NAIVE_VS_B1_BCELL_DN

UGGT1 TMEM117

8.43e-0419962M9796
CoexpressionGSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP

AFG3L2 PTDSS1

8.43e-0419962M5258
CoexpressionGSE45365_NK_CELL_VS_CD8A_DC_UP

UGGT1 NIPAL4

8.52e-0420062M10028
CoexpressionGSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN

UGGT1 AFG3L2

8.52e-0420062M4589
CoexpressionGSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_DN

AFG3L2 PTDSS1

8.52e-0420062M7829
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM117 NIPAL4

2.23e-04175629d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM117 NIPAL4

2.23e-0417562f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

UGGT1 NIPAL4

2.31e-04178629a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELMOD2 TMEM117

2.36e-0418062d33bb00f2b7d07dda9015cb8eafd742c2b2e9ace
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELMOD2 TMEM117

2.36e-04180625b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

TMEM117 PTDSS1

2.47e-0418462ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

TMEM117 PTDSS1

2.60e-0418962aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ComputationalNeighborhood of DEAF1

AFG3L2 PTDSS1

2.76e-055722MORF_DEAF1
ComputationalNeighborhood of BMI1

AFG3L2 PTDSS1

5.61e-058122MORF_BMI1
ComputationalNeighborhood of MAP2K2

AFG3L2 PTDSS1

1.50e-0413222MORF_MAP2K2
ComputationalNeighborhood of PPP1CC

AFG3L2 PTDSS1

2.37e-0416622MORF_PPP1CC
ComputationalNeighborhood of PRKDC

AFG3L2 PTDSS1

3.14e-0419122MORF_PRKDC
ComputationalNeighborhood of AATF

AFG3L2 PTDSS1

3.76e-0420922MORF_AATF
ComputationalNeighborhood of XRCC5

AFG3L2 PTDSS1

4.76e-0423522MORF_XRCC5
ComputationalNeighborhood of EIF3S2

AFG3L2 PTDSS1

5.22e-0424622MORF_EIF3S2
ComputationalNeighborhood of BUB3

AFG3L2 PTDSS1

6.62e-0427722MORF_BUB3
ComputationalNeighborhood of HDAC2

AFG3L2 PTDSS1

6.76e-0428022MORF_HDAC2
ComputationalNeighborhood of GNB1

AFG3L2 PTDSS1

8.03e-0430522MORF_GNB1
ComputationalNeighborhood of RAD23A

AFG3L2 PTDSS1

1.05e-0334822MORF_RAD23A
Diseasehereditary spastic paraplegia (implicated_via_orthology)

AFG3L2 NIPAL4

3.10e-054362DOID:2476 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
WEFFYGHFFRFWMKW

ELMOD2

6

Q8IZ81
KDFRMFFLWTALFWG

AFG3L2

141

Q9Y4W6
GFGYLKDAMWWAGFL

NIPAL4

96

Q0D2K0
WFGFFIWFFGRFLKN

TMEM117

406

Q9H0C3
DIFAFGHFWGWAMKA

PTDSS1

166

P48651
SENESGFWDSFKWGF

UGGT1

1226

Q9NYU2
GFWDSFKWGFTGQKT

UGGT1

1231

Q9NYU2
WFKAGFRFSDGWSMF

nan

56

Q8N9W7
WFKAGFRFSDGWSMF

nan

56

A6NDX4