Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	FLYWCH_N	FLYWCH1 FLYWCH2	1.90e-05	2	82	2	IPR029279
Domain	FLYWCH_N	FLYWCH1 FLYWCH2	1.90e-05	2	82	2	PF15423
Domain	NPIP	NPIPB8 NPIPB15 NPIPB6	2.87e-05	14	82	3	IPR009443
Domain	SET	SETD1A PRDM2 NSD3	7.71e-04	41	82	3	PF00856
Domain	SET	SETD1A PRDM2 NSD3	1.08e-03	46	82	3	SM00317
Domain	SET_dom	SETD1A PRDM2 NSD3	1.38e-03	50	82	3	IPR001214
Domain	SET	SETD1A PRDM2 NSD3	1.38e-03	50	82	3	PS50280
Domain	Post-SET_dom	SETD1A NSD3	2.20e-03	16	82	2	IPR003616
Domain	PostSET	SETD1A NSD3	2.20e-03	16	82	2	SM00508
Domain	POST_SET	SETD1A NSD3	2.20e-03	16	82	2	PS50868
Domain	RRM	SETD1A LARP4B IGF2BP2 RBM25 SPEN	2.67e-03	217	82	5	SM00360
Domain	Zinc_finger_PHD-type_CS	PHF1 PHF20 NSD3	2.93e-03	65	82	3	IPR019786
Domain	CH	MACF1 DMD SMTN	2.93e-03	65	82	3	SM00033
Domain	RRM_dom	SETD1A LARP4B IGF2BP2 RBM25 SPEN	3.24e-03	227	82	5	IPR000504
Domain	Ank	PPP1R12B POTED PPP1R16B TRPV4 POTEC	3.30e-03	228	82	5	PF00023
Domain	RRM	SETD1A LARP4B IGF2BP2 RBM25 SPEN	3.43e-03	230	82	5	PS50102
Domain	CH	MACF1 DMD SMTN	3.61e-03	70	82	3	PF00307
Domain	-	MACF1 DMD SMTN	3.76e-03	71	82	3	1.10.418.10
Domain	CH	MACF1 DMD SMTN	4.07e-03	73	82	3	PS50021
Domain	PHD	PHF1 PHF20 NSD3	4.39e-03	75	82	3	PF00628
Domain	CH-domain	MACF1 DMD SMTN	4.39e-03	75	82	3	IPR001715
Domain	-	SETD1A LARP4B IGF2BP2 RBM25 SPEN	4.40e-03	244	82	5	3.30.70.330
Domain	Actinin_actin-bd_CS	MACF1 DMD	4.54e-03	23	82	2	IPR001589
Domain	Spectrin	MACF1 DMD	4.54e-03	23	82	2	PF00435
Domain	ACTININ_2	MACF1 DMD	4.54e-03	23	82	2	PS00020
Domain	ACTININ_1	MACF1 DMD	4.54e-03	23	82	2	PS00019
Domain	ANK	PPP1R12B POTED PPP1R16B TRPV4 POTEC	4.96e-03	251	82	5	SM00248
Domain	Znf_PHD-finger	PHF1 PHF20 NSD3	5.07e-03	79	82	3	IPR019787
Domain	ANK_REPEAT	PPP1R12B POTED PPP1R16B TRPV4 POTEC	5.13e-03	253	82	5	PS50088
Domain	ANK_REP_REGION	PPP1R12B POTED PPP1R16B TRPV4 POTEC	5.21e-03	254	82	5	PS50297
Domain	Nucleotide-bd_a/b_plait	SETD1A LARP4B IGF2BP2 RBM25 SPEN	5.56e-03	258	82	5	IPR012677
Pubmed	Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen.	NCF1 SIGLEC14 SIGLEC5	5.25e-07	7	87	3	23840825
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	USP5 LARP4B RBM25 TRAFD1 MKI67 NHS PPHLN1 SPEN DDX24	4.87e-06	503	87	9	16964243
Pubmed	Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.	SIGLEC14 SIGLEC5	6.19e-06	2	87	2	24799499
Pubmed	Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.	SIGLEC14 SIGLEC5	6.19e-06	2	87	2	26459514
Pubmed	Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration.	MKI67 DMD CDC25B	8.27e-06	16	87	3	26275053
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	IGF2BP2 SPEN DDX24 KIF20B NSD3	8.30e-06	109	87	5	33554859
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	KIAA1217 NISCH NHS MACF1 DMD ITGAV FAM135A AKAP12	1.09e-05	421	87	8	36976175
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PPP4R1 ALMS1 KIAA1217 NCF1 E2F7 MACF1 SPEN FAM135A KIF20B	1.69e-05	588	87	9	38580884
Pubmed	Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	11579105
Pubmed	Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	30577572
Pubmed	A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	32247614
Pubmed	Three-dimensional mapping reveals heterochronic development of the neuromuscular system in postnatal mouse skeletal muscles.	MKI67 DMD	1.85e-05	3	87	2	36347940
Pubmed	Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses.	BATF3 ITGAV	1.85e-05	3	87	2	28473400
Pubmed	Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	25497369
Pubmed	Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	24698729
Pubmed	Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	17012248
Pubmed	Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	31520477
Pubmed	Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	23710953
Pubmed	Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	19783675
Pubmed	CDC25B, Ki-67, and p53 expressions in reactive gliosis and astrocytomas.	MKI67 CDC25B	1.85e-05	3	87	2	24344030
Pubmed	Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	32134149
Pubmed	Siglec-F is a novel intestinal M cell marker.	SIGLEC14 SIGLEC5	1.85e-05	3	87	2	27524237
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FLYWCH1 MKI67 FAM169A SPEN DDX24 ZHX1 KIF20B PRDM2 NSD3	2.20e-05	608	87	9	36089195
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM25 TRAFD1 MKI67 MED14 SPEN DDX24 ZHX1 UBE2E3 PRDM2 SMTN	2.40e-05	774	87	10	15302935
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	ALMS1 STARD9 MKI67 RPS6KA6 SRPK1 AKAP12	2.72e-05	233	87	6	37704626
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LARP4B RAP1GAP ALMS1 FAM169A MACF1 NLGN2 KHDC4 FAM135A	3.38e-05	493	87	8	15368895
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	PHF1 LARP4B ALMS1 MACF1 PPHLN1 CMYA5 UBE2E3 AKAP12	3.58e-05	497	87	8	23414517
Pubmed	Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.	SIGLEC14 SIGLEC5	3.70e-05	4	87	2	17562860
Pubmed	Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.	SIGLEC14 SIGLEC5	3.70e-05	4	87	2	17272508
Pubmed	Nephronectin plays critical roles in Sox2 expression and proliferation in dental epithelial stem cells via EGF-like repeat domains.	MKI67 NPNT	3.70e-05	4	87	2	28345658
Pubmed	Identification of Prognostic RBPs in Osteosarcoma.	IGF2BP2 DDX24	3.70e-05	4	87	2	33754909
Pubmed	Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.	SIGLEC14 SIGLEC5	3.70e-05	4	87	2	19178537
Pubmed	Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy.	DMD CMYA5	3.70e-05	4	87	2	18252718
Pubmed	Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes.	ADAM15 ITGAV	3.70e-05	4	87	2	22505472
Pubmed	Induction of Siglec-FhiCD101hi eosinophils in the lungs following murine hookworm Nippostrongylus brasiliensis infection.	SIGLEC14 SIGLEC5	3.70e-05	4	87	2	37251384
Pubmed	Loss of β2-spectrin prevents cardiomyocyte differentiation and heart development.	MKI67 DMD	3.70e-05	4	87	2	24064296
Pubmed	Membrane trafficking of NADPH oxidase p47(phox) in paraventricular hypothalamic neurons parallels local free radical production in angiotensin II slow-pressor hypertension.	AGT NCF1	3.70e-05	4	87	2	23467347
Pubmed	Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration.	SIGLEC14 SIGLEC5	3.70e-05	4	87	2	33289969
Pubmed	IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils.	SIGLEC14 SIGLEC5	3.70e-05	4	87	2	33976385
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	MACF1 DMD	3.70e-05	4	87	2	8954775
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP5 LARP4B IGF2BP2 RBM25 MKI67 MACF1 SRPK1 SPEN DDX24	3.83e-05	653	87	9	22586326
Pubmed	The basement membrane of hair follicle stem cells is a muscle cell niche.	DMD ITGAV NPNT	4.73e-05	28	87	3	21335239
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ALMS1 KIAA1217 MKI67 NHS MACF1 FAM135A	5.34e-05	263	87	6	34702444
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	EVI5 CRACD USP5 LARP4B IGF2BP2 TRAFD1 FLYWCH2 NCF1 MKI67 SRPK1 HMGCR DDX24 SMTN	5.88e-05	1440	87	13	30833792
Pubmed	NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice.	NCF1 DMD	6.16e-05	5	87	2	29381135
Pubmed	Piezo1 regulates the regenerative capacity of skeletal muscles via orchestration of stem cell morphological states.	MKI67 DMD	6.16e-05	5	87	2	35302846
Pubmed	Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.	SIGLEC14 SIGLEC5	6.16e-05	5	87	2	20395633
Pubmed	Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.	SIGLEC14 SIGLEC5	6.16e-05	5	87	2	21040544
Pubmed	Siglec-F-expressing neutrophils are essential for creating a profibrotic microenvironment in renal fibrosis.	SIGLEC14 SIGLEC5	6.16e-05	5	87	2	35482420
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	LARP4B IGF2BP2 RBM25 KIAA1217 MKI67 SRPK1 PPHLN1 SPEN DDX24 KIF20B NSD3 AFAP1L1	6.86e-05	1257	87	12	36526897
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SETD1A MKI67 SRPK1 PPHLN1 SPEN DDX24 KIF20B	7.81e-05	410	87	7	26949251
Pubmed	Myospryn is a novel binding partner for dysbindin in muscle.	DMD CMYA5	9.22e-05	6	87	2	14688250
Pubmed	Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle.	NCF1 DMD	9.22e-05	6	87	2	30504831
Pubmed	Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.	SIGLEC14 SIGLEC5	9.22e-05	6	87	2	23880769
Pubmed	Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions.	ADAM15 ITGAV	9.22e-05	6	87	2	11882657
Pubmed	Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G).	SIGLEC14 SIGLEC5	9.22e-05	6	87	2	14559209
Pubmed	Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.	IGF2BP2 RBM25 MKI67 PPHLN1	1.29e-04	102	87	4	26584622
Pubmed	Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.	SIGLEC14 SIGLEC5	1.29e-04	7	87	2	23677475
Pubmed	The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils.	SIGLEC14 SIGLEC5	1.29e-04	7	87	2	15048729
Pubmed	Ascl2 inhibits myogenesis by antagonizing the transcriptional activity of myogenic regulatory factors.	MKI67 DMD	1.29e-04	7	87	2	27993983
Pubmed	[Functions and molecular evolution of Siglecs, a family of sialic acid receptor proteins].	SIGLEC14 SIGLEC5	1.29e-04	7	87	2	18453149
Pubmed	MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.	MKI67 CDC25B	1.29e-04	7	87	2	21947081
Pubmed	Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle.	NCF1 DMD	1.29e-04	7	87	2	32506037
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	FANCE SETD1A FLYWCH1 MED14 ZHX1 KIF20B SMTN	1.45e-04	453	87	7	29656893
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTED POTEC	1.72e-04	8	87	2	12475935
Pubmed	Endothelin-1 regulates cardiac sympathetic innervation in the rodent heart by controlling nerve growth factor expression.	AGT MKI67	1.72e-04	8	87	2	15067320
Pubmed	The complex genetics of hypoplastic left heart syndrome.	MKI67 PCDHA12	1.72e-04	8	87	2	28530678
Pubmed	Atlas of Musculoskeletal Stem Cells with the Soft and Hard Tissue Differentiation Architecture.	MKI67 DMD	1.72e-04	8	87	2	33304744
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	SCG2 MKI67 MED14 PCDHA12 TSKS SPEN	1.82e-04	329	87	6	17474147
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	LARP4B RBM25 MKI67 SRPK1 PPHLN1 DDX24	1.91e-04	332	87	6	25693804
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	LARP4B IGF2BP2 RBM25 SPEN	1.98e-04	114	87	4	31553912
Pubmed	MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation.	NCF1 CDC25B	2.20e-04	9	87	2	15629715
Pubmed	Interaction network of human early embryonic transcription factors.	SETD1A ALMS1 MKI67 SPEN ZHX1 PRDM2	2.57e-04	351	87	6	38297188
Pubmed	Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells.	MKI67 DMD	2.75e-04	10	87	2	38875306
Pubmed	Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.	MKI67 DMD	3.35e-04	11	87	2	21989910
Pubmed	The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development.	MKI67 NFYC	3.35e-04	11	87	2	38199563
Pubmed	Selective Response to Bacterial Infection by Regulating Siglec-E Expression.	SIGLEC14 SIGLEC5	3.35e-04	11	87	2	32889432
Pubmed	PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.	MKI67 DMD	3.35e-04	11	87	2	37883229
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CRACD LARP4B FLYWCH1 PPP1R12B MED14 MACF1 SRPK1 PPHLN1 SPEN ZHX1 KIF20B NSD3	3.46e-04	1497	87	12	31527615
Pubmed	The protein interaction landscape of the human CMGC kinase group.	LARP4B RBM25 TRAFD1 ALMS1 MED14 RSRP1 SRPK1 PPHLN1	3.56e-04	695	87	8	23602568
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	RAP1GAP PPP1R12B MACF1	3.81e-04	56	87	3	9455484
Pubmed	Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.	FANCE MUCL3 NPNT	4.22e-04	58	87	3	23284291
Pubmed	CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.	SIGLEC14 SIGLEC5	4.74e-04	13	87	2	35921817
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	LARP4B IGF2BP2 SRPK1 CMYA5 SPEN	4.87e-04	258	87	5	37794589
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SETD1A KCNA5 ADAM15 PPP1R12B RPS6KA6 SRPK1 CDC25B NSD3	4.93e-04	730	87	8	34857952
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	CRACD IGF2BP2 ALMS1 FLYWCH2 KIAA1217 MKI67 FAM169A MACF1 AKAP12	5.52e-04	934	87	9	33916271
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CRACD KIAA0513 STARD9 NISCH MACF1 SPEN	5.63e-04	407	87	6	12693553
Pubmed	Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor.	NCF1 DMD	6.36e-04	15	87	2	11741599
Pubmed	Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system.	KCNA5 MKI67	6.36e-04	15	87	2	39239522
Pubmed	α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.	MKI67 ITGAV	6.36e-04	15	87	2	25670798
Pubmed	The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.	ALMS1 MKI67	6.36e-04	15	87	2	26035863
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	LARP4B IGF2BP2 MKI67 MED14 MACF1 SRPK1 DDX24 KIF20B	6.36e-04	759	87	8	35915203
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	LARP4B MED14 MACF1 SRPK1 DDX24	7.15e-04	281	87	5	24163370
Pubmed	Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion.	MKI67 HMGCR	7.26e-04	16	87	2	38042368
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	PPP4R1 LARP4B RBM25 DDX24	7.30e-04	161	87	4	32572027
Pubmed	Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.	RBM25 SRPK1 DDX24	7.96e-04	72	87	3	33106477
Pubmed	Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization.	SIGLEC14 SIGLEC5	8.21e-04	17	87	2	35709757
Pubmed	Human transcription factor protein interaction networks.	SETD1A LARP4B IGF2BP2 RBM25 ALMS1 MKI67 NFYC SPEN DDX24 ZHX1 PRDM2	8.67e-04	1429	87	11	35140242
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	CRACD USP5 TRAFD1 ZHX1	8.94e-04	170	87	4	23314748
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	LARP4B IGF2BP2 RBM25 MACF1 SRPK1 PPHLN1 SPEN DDX24	9.45e-04	807	87	8	22681889
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A PRDM2 NSD3	1.19e-04	34	51	3	487
GeneFamily	Ankyrin repeat domain containing	PPP1R12B POTED PPP1R16B TRPV4 POTEC	5.86e-04	242	51	5	403
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTED POTEC	5.97e-04	13	51	2	685
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R12B MKI67 PPP1R16B TSKS	1.68e-03	181	51	4	694
GeneFamily	PHD finger proteins	PHF1 PHF20 NSD3	2.09e-03	90	51	3	88
GeneFamily	CD molecules\|C2-set domain containing\|Sialic acid binding Ig like lectins	SIGLEC14 SIGLEC5	2.81e-03	28	51	2	745
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	CMYA5 AKAP12	3.02e-03	29	51	2	396
GeneFamily	RNA binding motif containing	SETD1A IGF2BP2 RBM25 SPEN	3.04e-03	213	51	4	725
GeneFamily	Tudor domain containing	PHF1 PHF20	4.88e-03	37	51	2	780
GeneFamily	Kinesins\|Pleckstrin homology domain containing	STARD9 KIF20B	7.46e-03	46	51	2	622
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	PPP4R1 EVI5 CRACD RBM25 PHF20 ALMS1 NCF1 MKI67 FAM169A NFYC MED14 E2F7 MACF1 PPHLN1 HMGCR DMD KHDC4 KIF20B	1.34e-06	1257	83	18	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	PPP4R1 EVI5 CRACD RBM25 PHF20 ALMS1 NCF1 MKI67 FAM169A NFYC RPS6KA6 MED14 E2F7 MACF1 PPHLN1 HMGCR DMD KHDC4 KIF20B	2.63e-06	1459	83	19	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	IGSF10 PPP4R1 EVI5 CRACD RBM25 RAP1GAP ALMS1 NCF1 MKI67 FAM169A NFYC NHS PPHLN1 KHDC4 FAM135A KIF20B NSD3	5.65e-06	1252	83	17	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	CRACD RBM25 PHF20 ALMS1 NCF1 MKI67 FAM169A RPS6KA6 PPP1R16B E2F7 MACF1 PPHLN1 HMGCR DMD KIF20B	1.35e-05	1060	83	15	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	IGSF10 PPP4R1 EVI5 RBM25 PHF20 ALMS1 DNAJC15 MKI67 FAM169A RPS6KA6 NHS MACF1 RSRP1 PPHLN1 UBE2E3 KIF20B	2.12e-05	1241	83	16	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_1000	SETD1A KCNA5 PHF20 STARD9 KIAA1217 NISCH NSD3	1.24e-04	284	83	7	gudmap_developingGonad_e16.5_epididymis_1000_k2
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500	IGSF10 PPP4R1 EVI5 RBM25 PHF20 ALMS1 DNAJC15 MKI67 FAM169A RPS6KA6 NHS MACF1 RSRP1 PPHLN1 UBE2E3 KIF20B	1.56e-04	1468	83	16	facebase_RNAseq_e10.5_MandArch_2500
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FANCE CARMIL3 PRR19 TSKS FAM135A AFAP1L1	7.92e-07	166	85	6	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PPP1R12B NHS MACF1 DMD NPNT SMTN	1.63e-06	188	85	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	RPS6KA6 NHS MACF1 DMD NPNT SMTN	1.69e-06	189	85	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 SCG2 NISCH MACF1 RSRP1 HMGCR	2.02e-06	195	85	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 SCG2 NISCH MACF1 RSRP1 HMGCR	2.02e-06	195	85	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNA5 PPP1R12B AGT AKAP12 NPNT SMTN	2.21e-06	198	85	6	705118a5db366b43ffd3389c60e4cb392ad3f2e6
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	KCNA5 PPP1R12B AGT DMD AKAP12 SMTN	2.27e-06	199	85	6	471738f2059e20407572d9c4cbd11812068333ea
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNA5 PPP1R12B DMD AKAP12 NPNT SMTN	2.27e-06	199	85	6	0a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KCNA5 PPP1R12B AGT DMD AKAP12 SMTN	2.27e-06	199	85	6	706b7de777ff86eb22e538ccd5c2987ceb6be308
ToppCell	ILEUM-non-inflamed-(8)_Smooth_muscle_cells\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PPP1R12B AGT DMD AKAP12 NPNT SMTN	2.27e-06	199	85	6	3368c0a90a47c4dcdfe70be3192550df0744e508
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNA5 PPP1R12B DMD AKAP12 NPNT SMTN	2.27e-06	199	85	6	c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KCNA5 PPP1R12B AGT DMD AKAP12 SMTN	2.27e-06	199	85	6	690a4f84b205532c4c9e5c19d5ae430d0655f421
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	IGF2BP2 KIAA1217 NHS TRPV4 DMD CMYA5	2.34e-06	200	85	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	KCNA5 NHS DMD AKAP12 NPNT	1.44e-05	161	85	5	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	FANCE CARMIL3 E2F7 BATF3 TSKS	1.71e-05	167	85	5	7efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CRACD KIAA0513 CARMIL3 SCG2 NHS	1.81e-05	169	85	5	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FANCE CARMIL3 E2F7 TSKS AFAP1L1	1.97e-05	172	85	5	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD MKI67 RPS6KA6 E2F7 KIF20B	2.03e-05	173	85	5	f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA5 PPP1R16B CDC25B AKAP12 SMTN	2.20e-05	176	85	5	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CARMIL3 RPS6KA6 MACF1 AKAP12 NPNT	2.20e-05	176	85	5	d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA5 PPP1R16B CDC25B AKAP12 SMTN	2.20e-05	176	85	5	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPIPB15 KIAA1217 MACF1 CMYA5 KHDC4	2.39e-05	179	85	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIAA1217 PPP1R16B MACF1 AKAP12 AFAP1L1	2.45e-05	180	85	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 FLYWCH1 SCG2 MACF1 PRDM2	2.45e-05	180	85	5	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 FLYWCH1 SCG2 MACF1 PRDM2	2.45e-05	180	85	5	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MKI67 PPHLN1 HMGCR CDC25B KIF20B	2.52e-05	181	85	5	3fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	2.73e-05	184	85	5	5cfc19ffb9f074bdf0d81c86e212a708ec141631
ToppCell	ILEUM-inflamed-(7)_Lymphatics\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	KIAA1217 CMYA5 AKAP12 AFAP1L1 SMTN	2.80e-05	185	85	5	d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNA5 AGT DMD AKAP12 SMTN	2.87e-05	186	85	5	c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	PPP1R12B NHS DMD AKAP12 SMTN	2.95e-05	187	85	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RBM25 MACF1 RSRP1 SPEN PRDM2	3.02e-05	188	85	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	KCNA5 PPP1R12B AGT NPNT SMTN	3.02e-05	188	85	5	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.10e-05	189	85	5	ab7ece0a517499b70b7754720d3e434765363af6
ToppCell	(3)_Chondrocytes-(31)_Chondro-hyper\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	RAP1GAP FLYWCH2 TRPV4 BATF3 MUCL3	3.10e-05	189	85	5	394b153393904c3dba51a6bfe338afd554e66649
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.18e-05	190	85	5	e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KCNA5 PPP1R12B AGT NHS DMD	3.18e-05	190	85	5	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	KCNA5 PPP1R12B AGT NHS DMD	3.26e-05	191	85	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.42e-05	193	85	5	a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	KCNA5 PPP1R12B DMD AKAP12 SMTN	3.42e-05	193	85	5	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.42e-05	193	85	5	b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.51e-05	194	85	5	93bc72a933ccc6a760e5353f072afb606571c6fc
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.51e-05	194	85	5	bea369e9a7018d862e4d7f1c9ec2de50f3fd38ec
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IGF2BP2 KIAA1217 PPP1R16B MACF1 AFAP1L1	3.51e-05	194	85	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIAA1217 PPP1R16B AKAP12 AFAP1L1 SMTN	3.51e-05	194	85	5	660535b492445063d965095a50e1e299ce04c50a
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNA5 PPP1R12B DMD NPNT SMTN	3.51e-05	194	85	5	aaecde88bd54134a938e76cdf059c1c2653e4e77
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)\|356C / Donor, Lineage, Cell class and subclass (all cells)	KCNA5 PPP1R12B AGT DMD SMTN	3.69e-05	196	85	5	a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 MACF1 TRPV4 DMD NPNT	3.69e-05	196	85	5	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 MACF1 TRPV4 DMD NPNT	3.69e-05	196	85	5	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	KCNA5 PPP1R12B AGT DMD SMTN	3.69e-05	196	85	5	476812fc1422aca8010d771eff11fa6081f15a2d
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNA5 PPP1R12B DMD NPNT SMTN	3.69e-05	196	85	5	4740ef6e428f1ccc81fc98c3b868afd38ce60535
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RBM25 FAM169A MACF1 DDX24 AKAP12	3.78e-05	197	85	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM15 MKI67 E2F7 CDC25B KIF20B	3.78e-05	197	85	5	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B DMD AKAP12 NPNT SMTN	3.78e-05	197	85	5	f4f686d20821af3e6f859b96edc31827a430e3de
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	KCNA5 PPP1R12B AGT DMD NPNT	3.87e-05	198	85	5	89986c7756541df364df516329d10775ba0e78a4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	MKI67 E2F7 CDC25B KIF20B SMTN	3.87e-05	198	85	5	dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNA5 PPP1R12B AGT AKAP12 SMTN	3.96e-05	199	85	5	ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	EVI5 RBM25 PPP1R12B AKAP12 NSD3	3.96e-05	199	85	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KCNA5 PPP1R12B AGT DMD SMTN	4.06e-05	200	85	5	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNA5 NHS DMD AKAP12 SMTN	4.06e-05	200	85	5	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KCNA5 PPP1R12B AGT DMD SMTN	4.06e-05	200	85	5	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IGF2BP2 ADAM15 KIAA1217 MACF1 FAM135A	4.06e-05	200	85	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PPP1R12B AGT BATF3 AKAP12 SMTN	4.06e-05	200	85	5	fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	KCNA5 PPP1R12B AGT DMD SMTN	4.06e-05	200	85	5	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	VE-CD4-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	ODAD1 PRR19 RPS6KA6 TSKS	1.09e-04	129	85	4	e89d414e1b23e1656747defa39f09b51944a2166
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	PPP1R12B DMD CMYA5 SMTN	1.30e-04	135	85	4	451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RBM25 MACF1 DDX24 FAM186B	1.30e-04	135	85	4	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RBM25 PPP1R12B MACF1 RSRP1	1.30e-04	135	85	4	b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIAA0513 AGT HMGCR CDC25B	1.54e-04	141	85	4	f3b1d757c4cac8596c542959c8f27f8bcaf3f513
ToppCell	367C-Epithelial_cells-Epithelial-D_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIAA0513 AGT HMGCR CDC25B	1.54e-04	141	85	4	bf68a54e755cda89fbc416636e522cd71d1e42d0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R16B CDC25B POTEC SMTN	1.67e-04	144	85	4	f501e11b1d051ca67124137017a79a2d5bb6ae87
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 E2F7 BATF3 KIF20B	2.15e-04	154	85	4	e3a8a1e63ab345de62bd2e5e54342b00f04ae422
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MACF1 RSRP1 KHDC4 NSD3	2.21e-04	155	85	4	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	KIAA1217 NHS TRPV4 AFAP1L1	2.26e-04	156	85	4	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	LAIR1 MACF1 RSRP1 NSD3	2.43e-04	159	85	4	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	Control-Endothelial_cells-Inflamed_endothelial_cells\|Control / group, cell type (main and fine annotations)	KIAA1217 PRR19 AKAP12 AFAP1L1	2.49e-04	160	85	4	958256e3d3836160763b82bb48f794087918d935
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MKI67 FAM169A E2F7 KIF20B	2.55e-04	161	85	4	2165897924c790fec43502283f1df221c56c1e9f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM15 PPP1R16B MUCL3 AFAP1L1	2.61e-04	162	85	4	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM15 PPP1R16B MUCL3 AFAP1L1	2.61e-04	162	85	4	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM15 SIGLEC14 E2F7 AFAP1L1	2.74e-04	164	85	4	1592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCell	facs-Heart-LA-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD PRR19 RPS6KA6 CMYA5	2.80e-04	165	85	4	95866f7cc6eb1bb51a034a104a0eb2a53b0256f2
ToppCell	facs-Heart-LA-18m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD PRR19 RPS6KA6 CMYA5	2.80e-04	165	85	4	f8bfe336b9a4460b9349c01acd0bd3167812662f
ToppCell	10x5'-Liver-Hematopoietic_progenitors\|Liver / Manually curated celltypes from each tissue	CRACD ODAD1 MKI67 NHS	2.87e-04	166	85	4	ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell	10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Liver / Manually curated celltypes from each tissue	CRACD ODAD1 MKI67 NHS	2.87e-04	166	85	4	a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF10 CRACD E2F7 BATF3	2.87e-04	166	85	4	49103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL3 SCG2 NISCH RSRP1	2.93e-04	167	85	4	b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CRACD KIAA0513 SCG2 NHS	2.93e-04	167	85	4	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD CMYA5 ITGAV NPNT	3.00e-04	168	85	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	metastatic_Brain-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	KCNA5 NPIPB6 PPP1R16B FAM186B	3.00e-04	168	85	4	4bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD CMYA5 ITGAV NPNT	3.00e-04	168	85	4	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLYWCH2 NLGN2 AFAP1L1 NPNT	3.14e-04	170	85	4	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLYWCH2 NLGN2 AFAP1L1 NPNT	3.14e-04	170	85	4	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLYWCH2 NLGN2 AFAP1L1 NPNT	3.14e-04	170	85	4	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MACF1 RSRP1 KHDC4 NSD3	3.21e-04	171	85	4	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	control-Myeloid-Mast_cell\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SPATA21 SCG2 NCF1 AKAP12	3.28e-04	172	85	4	c1c99e6732234a6649a79610e99390db0c8f19b0
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PPP1R12B NHS DMD SMTN	3.35e-04	173	85	4	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3\|TCGA-Breast / Sample_Type by Project: Shred V9	IGSF10 STARD9 PPP1R12B DMD	3.43e-04	174	85	4	7f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCell	TCGA-Breast-Solid_Tissue_Normal\|TCGA-Breast / Sample_Type by Project: Shred V9	IGSF10 STARD9 PPP1R12B DMD	3.43e-04	174	85	4	e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 E2F7 METTL15 KIF20B	3.43e-04	174	85	4	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MKI67 E2F7 METTL15 KIF20B	3.43e-04	174	85	4	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue\|TCGA-Breast / Sample_Type by Project: Shred V9	IGSF10 STARD9 PPP1R12B DMD	3.43e-04	174	85	4	0f3ec0d0d4344e10c9b48adc9174123f6402dc51
Disease	Malignant neoplasm of breast	RAP1GAP KCNA5 SPATA21 NISCH PPP1R12B MKI67 NFYC MED14 NHS MACF1 PPHLN1 DMD SPEN AKAP12	1.24e-06	1074	81	14	C0006142
Disease	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement	SIGLEC14 SIGLEC5	3.30e-04	10	81	2	EFO_0801544
Disease	Aortic Aneurysm, Abdominal	AGT NCF1	3.30e-04	10	81	2	C0162871
Disease	pulmonary hypertension (implicated_via_orthology)	KCNA5 AGT HMGCR	4.47e-04	54	81	3	DOID:6432 (implicated_via_orthology)
Disease	sialic acid-binding Ig-like lectin 14 measurement	SIGLEC14 SIGLEC5	4.83e-04	12	81	2	EFO_0008284
Disease	electroencephalogram measurement	E2F7 DMD CMYA5	1.12e-03	74	81	3	EFO_0004357
Disease	coronary artery disease	PHF1 IGSF10 CRACD IGF2BP2 KIAA1217 PPP1R12B AGT PPHLN1 HMGCR AKAP12	1.57e-03	1194	81	10	EFO_0001645
Disease	smoking cessation	ALMS1 KIAA1217 NLGN2 METTL15 UBE2E3	2.03e-03	325	81	5	EFO_0004319
Disease	Bradycardia	NISCH AGT	2.32e-03	26	81	2	C0428977
Disease	congestive heart failure (is_implicated_in)	NISCH AGT	2.50e-03	27	81	2	DOID:6000 (is_implicated_in)
Disease	pancreatic cancer (is_marker_for)	RAP1GAP ADAM15 MKI67	2.74e-03	101	81	3	DOID:1793 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LQPVQRAEAERPEEQ	AKAP12	1066	Q02952
EQQAESEKAPREPLE	ADAM15	31	Q13444
QISDPQRDQKVTPEQ	ALMS1	3576	Q8TCU4
QLEKEQESPRREPEQ	FAM186B	536	Q8IYM0
QEPRELPPEERAQNV	DMD	2886	P11532
QPQQQSPEDDDRKVR	BATF3	26	Q9NR55
LQQEARPAAQAPEKE	CCDC154	121	A6NI56
DEREPTESTQQLNKP	AGT	426	P01019
RRRQPQIKQEPESEE	RBM25	571	P49756
GEKEERPRQQDPQRN	FAM90A7	101	A6NKC0
EEDENKPQEKRPRAV	KIAA0513	261	O60268
ERRPDVVENQPDAAS	MAT2B	96	Q9NZL9
PPEDRNQRVVNVEDN	HSFX4	61	A0A1B0GTS1
DNRVQTDPQKPRGDV	NPNT	371	Q6UXI9
RAKVEDQELPTQPEA	FLYWCH1	391	Q4VC44
RERLPTTAQQEDPEK	FLYWCH1	671	Q4VC44
VLEEEENKPNPVTQR	HMGCR	241	P04035
DEEQKPQQRPDLAVD	LAIR1	201	Q6GTX8
IEAAPQEPEQKRSRQ	FLYWCH2	91	Q96CP2
QEPEQKRSRQDPGTD	FLYWCH2	96	Q96CP2
NESQPDSQEDPREVL	LARP4B	146	Q92615
PRLRLSSQQDQEEPE	CARMIL3	1311	Q8ND23
ERTEQKSPDIENVQP	FAM135A	581	Q9P2D6
EEERQTQRSKPQPAV	NCF1	351	P14598
ETRESNQVVQKERPP	EVI5	786	O60447
RKRVNENELQQDEPP	KIF20B	831	Q96Q89
VDEVEQSPKPKRQRE	NPIPB8	386	E9PQR5
RDQEPIPQNIDRVKA	MACF1	3031	O94854
RRSVTPPEEQQEAEE	CDC25B	351	P30305
RDQLPNDQPKRNDVS	RPS6KA6	686	Q9UK32
PRDQTPDENEEVIVR	IGF2BP2	546	Q9Y6M1
RRPQTPKEEAQALED	MKI67	1331	P46013
KVLSPQDQDVQDNPR	METTL15	381	A6NJ78
PPEDRNQRVVNVEDN	HSFX3	61	A0A1B0GWH4
EQSPKPKRQREAEAQ	NPIPB15	381	A6NHN6
NNDRQPDPDVLEKRE	ODAD1	231	Q96M63
PKRQEEVRQSVTPAE	NFYC	126	Q13952
QDARRRSVNEDDNPP	MED14	971	O60244
IRETRTDQENKDPNP	PPP1R16B	386	Q96T49
DEKNQPDPRLQELQE	GCC1	311	Q96CN9
REQEPQKKNRTDPNI	IGSF10	1346	Q6WRI0
KEEEKPLPRNEFQRQ	KCNA5	221	P22460
KPQEEDEPATKRQSR	E2F7	601	Q96AV8
QPSAKRPDADVDQQR	DNAJC15	21	Q9Y5T4
EPSEERLRNSPVQDE	CMYA5	3406	Q8N3K9
AQPPVERKEAAALEQ	CRACD	501	Q6ZU35
FKRVRPPQEEQEREQ	ITGAV	1021	P06756
RDARPALETQPQQEK	FAM169A	401	Q9Y6X4
REKPVPKQNENEEEN	DDX24	346	Q9GZR7
QPQAQKRRFTEELPD	KHDC4	456	Q7Z7F0
PEEEENRDSQQPGKR	FANCE	186	Q9HB96
EVEQSPKPKRQREAE	NPIPB6	381	E9PJ23
RKPSRELVDQDVQPA	NLGN2	331	Q8NFZ4
RQNEGNPERDKERPV	PPHLN1	181	Q8NEY8
KPREEPQSAAEQDVV	PRDM2	1111	Q13029
DKDPRVQENPGDQRR	POM121L1P	46	Q3SYA9
VQENPGDQRRVPEVT	POM121L1P	51	Q3SYA9
PAEPTENRERTANEN	MUCL3	301	Q3MIW9
VEVKDINDNPPVFRE	PCDHA12	121	Q9UN75
INDNPPVFREREQKV	PCDHA12	126	Q9UN75
KDPRVQENPDDQRTV	nan	6	A6NNC1
RSRKPENQQFPDTEN	POTEC	451	B2RU33
PENDIVKSPQENLRE	PHF20	241	Q9BVI0
SAVRNQPEPQEQRER	PHF1	391	O43189
RSRKPENQQFPDTEN	POTED	451	Q86YR6
RDQEAPEDVQVRPED	PPP4R1	351	Q8TF05
EEQERQERNRGQQPP	TRAFD1	216	O14545
PQQEESSEVPERKVL	SPATA21	366	Q7Z572
PRRVQQEIDSDESPV	NHS	406	Q6T4R5
IQEVQEKRESPPAGQ	RAP1GAP	506	P47736
EALRQAENEPQSAPK	SCG2	116	P13521
EDTPENTVRRQEQPS	KIAA1217	1631	Q5T5P2
EVVATNNPDRRVKPE	SIGLEC5	71	O15389
KRPNKQEESESPVER	SRPK1	301	Q96SB4
REQNTKRDIPDKAPQ	STARD9	3706	Q9P2P6
AEEPKPQQLQQQREE	SETD1A	1346	O15047
NRNAVPEVQTEKESP	SIX6OS1	456	Q8N1H7
EDGTRNPNEKPTQQR	RSRP1	231	Q9BUV0
QDEEPERPTGAQVKR	AFAP1L1	566	Q8TED9
PQQQRRSLKEEECPA	TNFRSF10D	71	Q9UBN6
ENEREQSPEKPRSCN	SPEN	841	Q96T58
INSPDQVPEQERQRK	PRR19	216	A6NJB7
EPEEQEERKPSATQQ	UBE2E3	31	Q969T4
RASNDQRPQEVPAEA	NISCH	1036	Q9Y2I1
ENEIKPDREEIVENP	ZHX1	211	Q9UKY1
PRRQEAELQEPEEKQ	TSKS	236	Q9UJT2
PEEQNRPNERVDTVS	NSD3	221	Q9BZ95
QPEQVETQPRAVSRE	ZKSCAN2	156	Q63HK3
ENPEEPEEVREQDQR	THEGL	56	P0DJG4
VPRVVELNKNSNPDE	TRPV4	826	Q9HBA0
REEQEQQAEVSKPTP	SMTN	161	P53814
EVVATNNPDRRVKPE	SIGLEC14	71	Q08ET2
RVPEQKEVQDGIAPR	USP5	401	P45974
AERQAQEQPREKPTD	PPP1R12B	666	O60237