Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

NUP62 NUP214 POM121C POM121B NUP153

1.35e-0825635GO:0017056
GeneOntologyMolecularFunctionnuclear localization sequence binding

NUP214 POM121C POM121B NUP153

1.50e-0627634GO:0008139
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D4 DLC1 SIPA1L1 TBCK ARHGAP39 AGAP4 AGAP6 USP6NL

2.62e-06279638GO:0005096
GeneOntologyMolecularFunctionsignal sequence binding

NUP214 POM121C POM121B NUP153

2.01e-0551634GO:0005048
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D4 DLC1 SIPA1L1 TBCK ARHGAP39 AGAP4 AGAP6 USP6NL SH3BP4

2.86e-05507639GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D4 DLC1 SIPA1L1 TBCK ARHGAP39 AGAP4 AGAP6 USP6NL SH3BP4

2.86e-05507639GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

STRADB TBC1D4 DLC1 SIPA1L1 TBCK ARHGAP39 AGAP4 AGAP6 USP6NL

2.05e-04656639GO:0008047
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

TCF4 ASXL1 TLE2 NSD1 MYOCD SORBS1 NUP62 ZZEF1 TRRAP NUP153 WWC1 MRTFA

2.37e-0411606312GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

TCF4 ASXL1 TLE2 NSD1 MLLT3 MYOCD SORBS1 NUP62 ZZEF1 TRRAP NUP153 WWC1 MRTFA

2.65e-0413566313GO:0060090
GeneOntologyMolecularFunctiontranscription coregulator activity

TCF4 ASXL1 TLE2 NSD1 MYOCD TRRAP WWC1 MRTFA

3.72e-04562638GO:0003712
GeneOntologyMolecularFunctionchromatin binding

EBF2 TCF4 ASXL1 ATXN7 MCM3AP NSD1 MLLT3 NUP62 NUP153

4.90e-04739639GO:0003682
GeneOntologyBiologicalProcessnuclear export

STRADB MCM3AP NUP62 NUP214 POM121C POM121B ADAR NUP153

9.15e-08185638GO:0051168
GeneOntologyBiologicalProcessRNA export from nucleus

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

4.76e-0796636GO:0006405
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D4 SIPA1L1 TBCK AGAP4 AGAP6 USP6NL

1.01e-06109636GO:0090630
GeneOntologyBiologicalProcessnuclear transport

STRADB MCM3AP PTPN22 NUP62 NUP214 POM121C POM121B ADAR NUP153

2.10e-06378639GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

STRADB MCM3AP PTPN22 NUP62 NUP214 POM121C POM121B ADAR NUP153

2.10e-06378639GO:0006913
GeneOntologyBiologicalProcessprotein import into nucleus

PTPN22 NUP62 NUP214 POM121C POM121B ADAR NUP153

2.14e-06195637GO:0006606
GeneOntologyBiologicalProcessimport into nucleus

PTPN22 NUP62 NUP214 POM121C POM121B ADAR NUP153

2.62e-06201637GO:0051170
GeneOntologyBiologicalProcessmRNA transport

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

5.32e-06145636GO:0051028
GeneOntologyBiologicalProcessRNA transport

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

1.56e-05175636GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

1.56e-05175636GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

1.72e-05178636GO:0051236
GeneOntologyBiologicalProcessnuclear pore organization

POM121C POM121B NUP153

2.14e-0518633GO:0006999
GeneOntologyBiologicalProcessRNA localization

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

5.22e-05217636GO:0006403
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D4 SIPA1L1 TBCK AGAP4 AGAP6 USP6NL SH3BP4

7.10e-05335637GO:0043087
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D4 SIPA1L1 TBCK AGAP4 AGAP6 USP6NL

9.97e-05244636GO:0043547
GeneOntologyBiologicalProcessnucleobase-containing compound transport

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

1.11e-04249636GO:0015931
GeneOntologyBiologicalProcessnegative regulation of protein localization to plasma membrane

NUMB PICALM WNK4

1.15e-0431633GO:1903077
GeneOntologyBiologicalProcessprotein localization to nucleus

PTPN22 NUP62 NUP214 POM121C POM121B ADAR NUP153

1.15e-04362637GO:0034504
GeneOntologyBiologicalProcessnegative regulation of protein localization to cell periphery

NUMB PICALM WNK4

1.39e-0433633GO:1904376
GeneOntologyBiologicalProcessnegative regulation of protein localization to membrane

NUMB PICALM WNK4

2.66e-0441633GO:1905476
GeneOntologyBiologicalProcessneuroblast proliferation

VCAN NUMB ZZEF1 CDON

2.89e-04104634GO:0007405
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D4 DLC1 SIPA1L1 VCAN TBCK AGAP4 AGAP6 USP6NL MRTFA SH3BP4

3.06e-048786310GO:0051336
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

DLC1 SIPA1L1 NUP62 ARHGAP39 PICALM CDON

5.30e-04333636GO:0051056
GeneOntologyBiologicalProcessnegative regulation of protein kinase activity

PTPN22 MYOCD NUP62 ADAR WNK4

5.72e-04221635GO:0006469
GeneOntologyBiologicalProcessregulation of protein localization to plasma membrane

NUMB SORBS1 PICALM WNK4

6.35e-04128634GO:1903076
GeneOntologyBiologicalProcessnegative regulation of kinase activity

PTPN22 MYOCD NUP62 ADAR WNK4

7.70e-04236635GO:0033673
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D4 DLC1 SIPA1L1 TBCK AGAP4 AGAP6 USP6NL

7.98e-04499637GO:0051345
GeneOntologyCellularComponentnuclear pore

MCM3AP NUP62 NUP214 POM121C POM121B NUP153

5.95e-07101636GO:0005643
GeneOntologyCellularComponentnuclear protein-containing complex

TCF4 ASXL1 ATXN7 MCM3AP NSD1 MLLT3 MYOCD NUP62 NUP214 POM121C MGA POM121B TRRAP ADAR NUP153

1.07e-0513776315GO:0140513
GeneOntologyCellularComponentGolgi lumen

VCAN MUC16 MUC5B MUC3A MUC6

1.94e-05109635GO:0005796
GeneOntologyCellularComponentnuclear membrane

TEX2 MCM3AP NUP62 POM121C POM121B NUP153

6.33e-04349636GO:0031965
GeneOntologyCellularComponentannulate lamellae

NUP62 NUP153

7.95e-0414632GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

MCM3AP NUP153

1.33e-0318632GO:0044615
GeneOntologyCellularComponenttranscription factor TFTC complex

ATXN7 TRRAP

1.33e-0318632GO:0033276
GeneOntologyCellularComponentnuclear envelope

TEX2 MCM3AP NUP62 NUP214 POM121C POM121B NUP153

1.44e-03560637GO:0005635
GeneOntologyCellularComponentclathrin-coated pit

NUMB PICALM SH3BP4

1.82e-0380633GO:0005905
GeneOntologyCellularComponentinclusion body

STRADB PICALM NUP153

2.54e-0390633GO:0016234
GeneOntologyCellularComponentSAGA complex

ATXN7 TRRAP

2.56e-0325632GO:0000124
DomainRPEL

MYOCD MRTFA

2.11e-047602PS51073
DomainRPEL

MYOCD MRTFA

2.11e-047602PF02755
DomainRPEL

MYOCD MRTFA

2.11e-047602SM00707
DomainRPEL_repeat

MYOCD MRTFA

2.11e-047602IPR004018
DomainTBC

TBC1D4 TBCK USP6NL

5.23e-0449603SM00164
DomainTIL

MUC5B MUC6

6.56e-0412602PF01826
DomainC8

MUC5B MUC6

6.56e-0412602PF08742
DomainRabGAP-TBC

TBC1D4 TBCK USP6NL

6.59e-0453603PF00566
DomainTBC_RABGAP

TBC1D4 TBCK USP6NL

7.34e-0455603PS50086
DomainRab-GTPase-TBC_dom

TBC1D4 TBCK USP6NL

7.34e-0455603IPR000195
DomainUnchr_dom_Cys-rich

MUC5B MUC6

7.74e-0413602IPR014853
DomainC8

MUC5B MUC6

7.74e-0413602SM00832
DomainSEA

MUC16 MUC3A

9.01e-0414602SM00200
DomainTIL_dom

MUC5B MUC6

9.01e-0414602IPR002919
DomainVWD

MUC5B MUC6

1.18e-0316602SM00216
DomainVWF_type-D

MUC5B MUC6

1.18e-0316602IPR001846
DomainVWFD

MUC5B MUC6

1.18e-0316602PS51233
DomainVWD

MUC5B MUC6

1.18e-0316602PF00094
Domain-

TBC1D4 NUMB PLEKHS1 PLEKHA6 AGAP4 AGAP6

1.56e-033916062.30.29.30
DomainVWC_out

MUC5B MUC6

1.68e-0319602SM00215
DomainPH

TEX2 PLEKHS1 PLEKHA6 AGAP4 AGAP6

1.97e-03278605SM00233
DomainPH_domain

TEX2 PLEKHS1 PLEKHA6 AGAP4 AGAP6

2.04e-03280605IPR001849
Domain-

MYOCD MRTFA

2.05e-03216021.10.720.30
DomainCT

MUC5B MUC6

2.25e-0322602SM00041
DomainSAP

MYOCD MRTFA

2.25e-0322602PF02037
DomainPH_dom-like

TBC1D4 NUMB PLEKHS1 PLEKHA6 AGAP4 AGAP6

2.41e-03426606IPR011993
DomainSAP

MYOCD MRTFA

2.46e-0323602SM00513
DomainSEA

MUC16 MUC3A

2.46e-0323602PS50024
DomainSEA_dom

MUC16 MUC3A

2.46e-0323602IPR000082
DomainSAP

MYOCD MRTFA

2.90e-0325602PS50800
DomainCys_knot_C

MUC5B MUC6

2.90e-0325602IPR006207
DomainSAP_dom

MYOCD MRTFA

2.90e-0325602IPR003034
DomainCTCK_2

MUC5B MUC6

2.90e-0325602PS01225
DomainZnf_PHD

ASXL1 PHF3 NSD1

3.13e-0391603IPR001965
DomainZF_PHD_2

ASXL1 PHF3 NSD1

3.54e-0395603PS50016
DomainPID

TBC1D4 NUMB

3.64e-0328602PF00640
DomainZF_PHD_1

ASXL1 PHF3 NSD1

3.64e-0396603PS01359
DomainArfGap

AGAP4 AGAP6

3.90e-0329602SM00105
DomainArfGap

AGAP4 AGAP6

3.90e-0329602PF01412
DomainARFGAP

AGAP4 AGAP6

3.90e-0329602PS50115
DomainArfGAP

AGAP4 AGAP6

3.90e-0329602IPR001164
DomainPID

TBC1D4 NUMB

4.73e-0332602PS01179
DomainHLH

EBF2 TCF4 MGA

6.18e-03116603SM00353
DomainPTB

TBC1D4 NUMB

7.32e-0340602SM00462
DomainPTB/PI_dom

TBC1D4 NUMB

7.68e-0341602IPR006020
DomainVWF_dom

MUC5B MUC6

8.05e-0342602IPR001007
DomainANK_REPEAT

MUC16 AGAP4 AGAP6 TP53BP2

8.86e-03253604PS50088
DomainANK_REP_REGION

MUC16 AGAP4 AGAP6 TP53BP2

8.98e-03254604PS50297
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC3A MUC6

1.75e-0716464M27410
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP62 NUP214 POM121C POM121B NUP153

1.79e-0740465MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP62 NUP214 POM121C POM121B NUP153

2.03e-0741465MM15200
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC3A MUC6

2.29e-0717464M27412
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP62 NUP214 POM121C POM121B NUP153

2.30e-0742465MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP62 NUP214 POM121C POM121B NUP153

2.60e-0743465MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP62 NUP214 POM121C POM121B NUP153

4.10e-0747465MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP62 NUP214 POM121C POM121B NUP153

5.07e-0749465MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP62 NUP214 POM121C POM121B NUP153

5.62e-0750465MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP62 NUP214 POM121C POM121B NUP153

6.21e-0751465MM15151
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC3A MUC6

8.40e-0723464M556
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP62 NUP214 POM121C POM121B NUP153

9.11e-0755465MM14917
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP62 NUP214 POM121C POM121B NUP153

1.19e-0658465MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

NUP62 NUP214 POM121C POM121B NUP153

1.19e-0658465MM14736
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC3A MUC6

1.41e-0626464M27483
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP62 NUP214 POM121C POM121B NUP153

2.11e-0665465MM15147
PathwayREACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN

NUP62 NUP214 POM121C NUP153

3.34e-0632464M29579
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP62 NUP214 POM121C POM121B NUP153

3.77e-0673465MM14948
PathwayREACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS

NUP62 NUP214 POM121C NUP153

3.79e-0633464M27016
PathwayREACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN

NUP62 NUP214 POM121C NUP153

4.28e-0634464M27041
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

NUP62 NUP214 POM121C NUP153

4.82e-0635464M27320
PathwayBIOCARTA_NPC_PATHWAY

NUP62 NUP214 NUP153

5.27e-0611463M22033
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

NUP62 NUP214 POM121C NUP153

5.41e-0636464M27245
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

NUP62 NUP214 POM121C NUP153

5.41e-0636464M26974
PathwayREACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS

NUP62 NUP214 POM121C NUP153

6.06e-0637464M1029
PathwayREACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS

NUP62 NUP214 POM121C NUP153

6.06e-0637464M27038
PathwayREACTOME_GLUCOSE_METABOLISM

NUP62 NUP214 POM121C POM121B NUP153

6.69e-0682465MM15394
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

NUP62 NUP214 POM121C NUP153

7.51e-0639464M27238
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP62 NUP214 POM121C POM121B NUP153

7.54e-0684465MM14929
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP62 NUP214 POM121C POM121B NUP153

8.46e-0686465MM15413
PathwayREACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS

NUP62 NUP214 POM121C NUP153

9.20e-0641464M29574
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

NUP62 NUP214 POM121C NUP153

1.12e-0543464M26975
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP62 NUP214 POM121C POM121B NUP153

1.18e-0592465MM14951
PathwayREACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS

NUP62 NUP214 POM121C NUP153

1.22e-0544464M109
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

NUP62 NUP214 POM121C NUP153

1.46e-0546464M27397
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

NUP62 NUP214 POM121C NUP153

1.60e-0547464M27395
PathwayREACTOME_SUMOYLATION

NUP62 NUP214 POM121C POM121B NUP153 MRTFA

1.71e-05169466MM14919
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

NUP62 NUP214 POM121C NUP153

2.58e-0553464M27212
PathwayREACTOME_SNRNP_ASSEMBLY

NUP62 NUP214 POM121C NUP153

2.78e-0554464M29594
PathwayREACTOME_MITOTIC_PROPHASE

NUP62 NUP214 POM121C POM121B NUP153

3.33e-05114465MM15361
PathwayREACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS

NUP62 NUP214 POM121C NUP153

3.96e-0559464M27606
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC6

4.15e-0521463MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC3A MUC6

4.82e-0562464M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC3A MUC6

6.94e-0568464M27303
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

NUP62 NUP214 POM121C NUP153

8.22e-0571464M27394
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

NUP62 NUP214 POM121C NUP153

9.66e-0574464M48006
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

VCAN MUC16 MUC5B MUC3A MUC6

9.82e-05143465M27275
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

NUP62 NUP214 POM121C NUP153

1.13e-0477464M27226
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

NUP62 NUP214 POM121C ADAR NUP153

1.27e-04151465M550
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TCF4 TLE2 VCAN TRRAP

1.31e-0480464M223
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP62 NUP214 POM121C NUP153

1.44e-0482464M27250
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

NUP62 NUP214 POM121C NUP153

1.58e-0484464M725
PathwayREACTOME_GLUCOSE_METABOLISM

NUP62 NUP214 POM121C NUP153

1.66e-0485464M1870
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

VCAN NUP62 NUP214 POM121C POM121B NUP153

2.35e-04271466MM15406
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

NUP62 NUP214 POM121C NUP153

2.98e-0499464M27474
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP62 NUP214 POM121C NUP153

3.22e-04101464M27253
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

ASXL1 ATXN7 VCAN MUC16 MUC5B NUP62 NUP214 POM121C POM121B TRRAP MUC6 NUP153 MRTFA

3.55e-0413894613MM15307
PathwayREACTOME_SUMOYLATION

NUP62 NUP214 POM121C NUP153 MRTFA

3.61e-04189465M27214
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

NUP62 NUP214 POM121C NUP153

3.87e-04106464M27458
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC3A MUC6

4.61e-04111464M27416
PathwayREACTOME_TRNA_PROCESSING

NUP62 NUP214 POM121C NUP153

4.61e-04111464M27684
PathwayREACTOME_HCMV_LATE_EVENTS

NUP62 NUP214 POM121C NUP153

5.44e-04116464M29806
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

ASXL1 ATXN7 VCAN MUC16 MUC5B NUP62 NUP214 POM121C TRRAP MUC3A MUC6 NUP153 MRTFA

6.36e-0414754613M19806
PathwayREACTOME_SARS_COV_2_ACTIVATES_MODULATES_INNATE_AND_ADAPTIVE_IMMUNE_RESPONSES

NUP62 NUP214 POM121C NUP153

7.43e-04126464M45009
PathwayREACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS

NUP62 NUP214 POM121C NUP153

8.59e-04131464M5283
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC6

9.77e-0460463MM15636
PathwayREACTOME_HCMV_EARLY_EVENTS

NUP62 NUP214 POM121C NUP153

1.04e-03138464M29805
PathwayREACTOME_GENE_SILENCING_BY_RNA

NUP62 NUP214 POM121C NUP153

1.07e-03139464M715
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC3A MUC6

1.10e-03140464M27484
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

SZT2 NUP62 NUP214 POM121C POM121B NUP153 SH3BP4

1.16e-03505467MM15548
PathwayREACTOME_MITOTIC_PROPHASE

NUP62 NUP214 POM121C NUP153

1.16e-03142464M27660
PathwayPID_SMAD2_3PATHWAY

NUP214 NUP153

1.21e-0316462M228
PathwayREACTOME_DISEASES_OF_METABOLISM

VCAN MUC16 MUC5B MUC3A MUC6

1.28e-03250465M27554
PathwayREACTOME_HIV_LIFE_CYCLE

NUP62 NUP214 POM121C NUP153

1.39e-03149464M4076
PathwayREACTOME_INFLUENZA_INFECTION

NUP62 NUP214 POM121C NUP153

1.68e-03157464M4669
PathwayREACTOME_INTERFERON_SIGNALING

NUP62 NUP214 POM121C ADAR NUP153

1.88e-03273465M983
PathwayREACTOME_HCMV_INFECTION

NUP62 NUP214 POM121C NUP153

1.88e-03162464M29804
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

NUP62 NUP214 POM121C POM121B NUP153

2.00e-03277465MM15414
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

VCAN NUP62 NUP214 POM121C NUP153

2.37e-03288465M16864
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

NUP62 NUP214 POM121C NUP153

2.60e-03177464M27476
PathwayREACTOME_MYOGENESIS

TCF4 CDON

2.75e-0324462MM15174
PathwayREACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION

POM121C POM121B

2.75e-0324462MM15658
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TLE2 TRRAP

3.22e-0326462MM14793
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TCF4 TLE2 TRRAP

3.23e-0391463M27101
PathwayREACTOME_MYOGENESIS

TCF4 CDON

4.00e-0329462M853
PathwayKEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA

NUP62 NUP214

4.28e-0330462M47752
PathwayREACTOME_SARS_COV_2_HOST_INTERACTIONS

NUP62 NUP214 POM121C NUP153

4.32e-03204464M45011
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

ESRRG MLLT3 NUP62 NUP214 POM121C MGA POM121B NUP153 TP53BP2

5.13e-031022469MM15436
PathwayWP_PRADERWILLI_AND_ANGELMAN_SYNDROME

NUP62 NUP214 NUP153

5.36e-03109463M39542
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC6

5.36e-03109463MM15164
PathwayREACTOME_HIV_INFECTION

NUP62 NUP214 POM121C NUP153

6.69e-03231464M12469
PathwayREACTOME_M_PHASE

NUP62 NUP214 POM121C POM121B NUP153

8.27e-03387465MM15364
PathwayPID_P53_DOWNSTREAM_PATHWAY

VCAN TRRAP TP53BP2

1.00e-02137463M145
PathwayWP_RETT_SYNDROME

TCF4 TRRAP

1.07e-0248462M39759
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NUMB PTPN22 NUP214 POM121C MGA TRIP12 PICALM WNK4 NUP153 MRTFA TP53BP2 SH3BP4

2.01e-11430641235044719
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

NUP62 NUP214 POM121C POM121B NUP153

5.33e-111564514697343
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TBC1D4 DLC1 TEX2 PHF3 SIPA1L1 NUMB SORBS1 NUP62 PPIP5K2 TRIP12 USP6NL WNK4 TP53BP2 SH3BP4

4.45e-10861641436931259
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

NUP62 NUP214 POM121C POM121B NUP153

8.62e-093864512791264
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC3A MUC6

3.13e-081864418834073
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

TCF4 DYM TEX2 SIPA1L1 SORBS1 PPIP5K2 AGAP4 AGAP6 WWC1 SH3BP4

5.00e-08536641015840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

TCF4 DYM TEX2 SIPA1L1 SORBS1 PPIP5K2 AGAP4 AGAP6 WWC1 SH3BP4

5.17e-08538641010512203
Pubmed

The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase.

NUP62 NUP214 NUP153

5.93e-08564316730000
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

PHF3 NUP62 NUP214 ZBTB11 POM121C TRRAP ADAR TRIP12 NUP153

1.14e-0744064934244565
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B MUC6

1.18e-07664319110483
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

SIPA1L1 SORBS1 ARHGAP39 AGAP4 AGAP6 WWC1 TP53BP2

1.58e-0721864733378226
Pubmed

Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.

NUP62 NUP214 NUP153

2.07e-07764311238447
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

NUP62 NUP214 NUP153

3.31e-07864331375530
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TBC1D4 PHF3 NUMB PLEKHA6 ADAR TRIP12 NUP153 MRTFA SH3BP4

3.51e-0750364916964243
Pubmed

Cloning and characterization of human karyopherin beta3.

NUP62 NUP214 NUP153

4.95e-0796439114010
Pubmed

The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control.

NUP62 NUP214 NUP153

7.07e-071064318596238
Pubmed

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.

NUP62 NUP214 NUP153

7.07e-071064319581287
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

PHF3 SIPA1L1 SORBS1 ARHGAP39 AGAP4 AGAP6 TP53BP2

8.74e-0728164728706196
Pubmed

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

NUP62 NUP214 ADAR NUP153

9.06e-074064437516964
Pubmed

GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.

MCM3AP NUP62 NUP153

9.70e-071164323652018
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

MCM3AP NUMB POM121C USP6NL NUP153 SH3BP4

1.03e-0618064635198878
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TBC1D4 ATXN7 PHF3 SIPA1L1 NUP214 ARHGAP39 TRRAP TRIP12 NUP153 MRTFA

1.44e-06774641015302935
Pubmed

TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.

NUP62 NUP214 NUP153

2.13e-061464311073998
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

TBC1D4 TEX2 SIPA1L1 PICALM WWC1 TP53BP2

2.46e-0620964636779422
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

MCM3AP NUP62 NUP214 POM121C ADAR TRIP12 NUP153

2.64e-0633264725693804
Pubmed

A human MAP kinase interactome.

MCM3AP SORBS1 NUP214 PLEKHA6 POM121C MGA NUP153 SH3BP4

3.06e-0648664820936779
Pubmed

BGLF4 kinase modulates the structure and transport preference of the nuclear pore complex to facilitate nuclear import of Epstein-Barr virus lytic proteins.

NUP62 NUP153

3.33e-06264225410863
Pubmed

Nuclear import of cutaneous beta genus HPV8 E7 oncoprotein is mediated by hydrophobic interactions between its zinc-binding domain and FG nucleoporins.

NUP62 NUP153

3.33e-06264224418548
Pubmed

Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions.

ATXN7 SORBS1

3.33e-06264211371513
Pubmed

Myocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis.

MYOCD MRTFA

3.33e-06264231928221
Pubmed

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells.

MYOCD MRTFA

3.33e-06264214970199
Pubmed

Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes.

NUP62 NUP214

3.33e-06264222558357
Pubmed

Inhibition of nuclear import and alteration of nuclear pore complex composition by rhinovirus.

NUP62 NUP153

3.33e-06264212163599
Pubmed

Structural basis for recognition of the third SH3 domain of full-length R85 (R85FL)/ponsin by ataxin-7.

ATXN7 SORBS1

3.33e-06264223892081
Pubmed

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

NUP62 NUP214 NUP153

3.97e-061764310668806
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TBC1D4 SIPA1L1 MCM3AP SORBS1 TRIP12

4.31e-0613064512421765
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

NUMB POM121C PICALM USP6NL NUP153 TP53BP2

9.17e-0626364634702444
Pubmed

The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.

DLC1 MRTFA

9.99e-06364222139079
Pubmed

Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation.

MYOCD MRTFA

9.99e-06364217363709
Pubmed

Interactions and three-dimensional localization of a group of nuclear pore complex proteins.

NUP62 NUP153

9.99e-0636428045926
Pubmed

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus.

NUP214 NUP153

9.99e-06364212191473
Pubmed

POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.

POM121C POM121B

9.99e-06364230802453
Pubmed

Myocardin-related transcription factor contributes to renal fibrosis through the regulation of extracellular microenvironment surrounding fibroblasts.

MYOCD MRTFA

9.99e-06364237289107
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

9.99e-06364227230679
Pubmed

Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

POM121C POM121B

9.99e-06364235507432
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP214 NUP153

9.99e-0636429847314
Pubmed

RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding.

MYOCD MRTFA

9.99e-06364218025109
Pubmed

Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice.

MYOCD MRTFA

9.99e-06364223103763
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP214 NUP153

9.99e-06364221327100
Pubmed

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor.

MYOCD MRTFA

9.99e-06364211439182
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

MCM3AP NUP62 NUP214 NUP153

1.28e-057764424927568
Pubmed

Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.

NUP62 NUP214 NUP153

1.33e-052564310601273
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

SIPA1L1 VCAN NUMB SORBS1 ARHGAP39 AGAP4 AGAP6

1.42e-0543064732581705
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

TMTC3 TEX2 SIPA1L1 MCM3AP NUMB NUP62 NUP214 POM121C PICALM USP6NL

1.45e-051007641034597346
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

NUP62 NUP214 NUP153

1.50e-052664312228227
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

TBC1D4 PHF3 SIPA1L1 MLLT3 NUP214 PLEKHA6 MGA TRIP12 WWC1 TP53BP2 SH3BP4

1.57e-051247641127684187
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

LINC01600 DLC1 SIPA1L1 PLEKHS1 PTPN22 SORBS1 POM121C USP6NL NUP153

1.76e-0581464923251661
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC6

2.00e-05464217471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC6

2.00e-05464214984930
Pubmed

Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2.

NUP62 NUP153

2.00e-05464215522285
Pubmed

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

POM121C POM121B

2.00e-05464217900573
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC6

2.00e-05464229869461
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC5B MUC6

2.00e-05464221596555
Pubmed

The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression.

MYOCD MRTFA

2.00e-05464217991879
Pubmed

Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells.

NUP62 NUP153

2.00e-05464230022050
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC6

2.00e-05464223807779
Pubmed

Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins.

NUP62 NUP153

2.00e-05464224739174
Pubmed

Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

MYOCD MRTFA

2.00e-05464212397177
Pubmed

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.

TCF4 MLLT3

2.00e-05464227374225
Pubmed

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.

NUP62 NUP214

2.00e-05464230543681
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC6

2.00e-05464212676567
Pubmed

Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation.

MYOCD MRTFA

2.00e-05464216204380
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

TMTC3 PHF3 NSD1 NUP62 NUP214 POM121C MGA TRRAP ADAR TRIP12 NUP153

2.20e-051294641130804502
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

NUP62 NUP214 NUP153

2.33e-053064324315095
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

NUP62 NUP214 NUP153

2.33e-053064327016207
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PHF3 MCM3AP NSD1 NUP214 ZBTB11 TRRAP TRIP12 NUP153

2.60e-0565364822586326
Pubmed

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding.

MYOCD MRTFA

3.32e-05564218945672
Pubmed

Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins.

NUP62 NUP153

3.32e-05564223840580
Pubmed

A giant nucleopore protein that binds Ran/TC4.

NUP214 NUP153

3.32e-0556427603572
Pubmed

Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export.

NUP62 NUP214

3.32e-05564211425870
Pubmed

Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.

ATXN7 TRRAP

3.32e-05564216494529
Pubmed

Muscle-specific signaling mechanism that links actin dynamics to serum response factor.

MYOCD MRTFA

3.32e-05564215798203
Pubmed

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

MUC5B MUC6

3.32e-05564224840470
Pubmed

RanGTP mediates nuclear pore complex assembly.

NUP62 NUP153

3.32e-05564212894213
Pubmed

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

NUP214 NUP153

3.32e-05564212917407
Pubmed

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains.

NUP214 NUP153

3.32e-05564212138183
Pubmed

Essential role of KIBRA in co-activator function of dynein light chain 1 in mammalian cells.

DLC1 WWC1

3.32e-05564216684779
Pubmed

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.

NUP214 NUP153

3.32e-05564211777942
Pubmed

Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.

NUP62 NUP214

3.32e-05564219828735
Pubmed

The nuclear pore complex: from molecular architecture to functional dynamics.

NUP62 NUP214

3.32e-05564210395558
Pubmed

Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation.

MYOCD MRTFA

3.32e-05564217360478
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

NUP62 NUP214 NUP153

3.41e-053464318539113
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

HOXD11 PTPN22 SORBS1 NUP214 TRRAP TRIP12 WNK4

3.59e-0549764736774506
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CEP68 TBC1D4 MCM3AP MGA

4.34e-051056449628581
Pubmed

A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution.

NUMB SH3BP4

4.98e-0566427568168
Pubmed

Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.

NUP62 NUP153

4.98e-05664211266456
Pubmed

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

ATXN7 TRRAP

4.98e-05664215115762
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

TCF4 NSD1 MGA TRIP12

5.02e-0510964433554859
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SZT2 TEX2 PPIP5K2 ZZEF1 AGAP4 AGAP6 USP6NL

5.32e-0552964714621295
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PHF3 NSD1 NUP62 NUP214 MGA ADAR TRIP12 PICALM NUP153

6.03e-0595464936373674
InteractionPARD3 interactions

SIPA1L1 NUMB SORBS1 ARHGAP39 PLEKHA6 USP6NL TP53BP2 SH3BP4

4.49e-06298648int:PARD3
InteractionYWHAG interactions

TBC1D4 DLC1 NHSL2 PHF3 SIPA1L1 NUMB SORBS1 NUP62 PPIP5K2 TRRAP TRIP12 USP6NL WWC1 TP53BP2 SH3BP4

6.24e-0612486415int:YWHAG
InteractionYWHAH interactions

TBC1D4 NHSL2 TEX2 PHF3 SIPA1L1 NUMB SORBS1 NUP62 PPIP5K2 TRIP12 USP6NL WWC1 TP53BP2 SH3BP4

7.22e-0611026414int:YWHAH
InteractionSYNE3 interactions

TMTC3 TEX2 SIPA1L1 SORBS1 NUP62 NUP214 POM121C PICALM TP53BP2

1.06e-05444649int:SYNE3
InteractionSEH1L interactions

SZT2 NUP62 NUP214 POM121C TRRAP NUP153

1.09e-05158646int:SEH1L
InteractionNUP43 interactions

SZT2 MCM3AP NSD1 NUP62 NUP214 ZBTB11 POM121C MGA TRIP12 NUP153

2.56e-056256410int:NUP43
InteractionSFN interactions

TBC1D4 TEX2 PHF3 SIPA1L1 NUMB SORBS1 TRIP12 USP6NL TP53BP2 SH3BP4

6.06e-056926410int:SFN
InteractionDPPA3 interactions

MCM3AP NUP62 NUP214 POM121C

6.10e-0567644int:DPPA3
InteractionYWHAB interactions

TBC1D4 PHF3 SIPA1L1 NUMB SORBS1 PPIP5K2 TRRAP TRIP12 USP6NL WWC1 TP53BP2 SH3BP4

7.17e-0510146412int:YWHAB
InteractionSTAMBPL1 interactions

TCF4 SIPA1L1 NUMB PICALM

9.49e-0575644int:STAMBPL1
InteractionPHF21A interactions

TBC1D4 NUP62 NUP214 ZBTB11 MGA MRTFA TP53BP2

1.05e-04343647int:PHF21A
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC3A MUC6

1.20e-0721404648
GeneFamilyNucleoporins

NUP62 NUP214 NUP153

4.76e-05324031051
GeneFamilyLysine acetyltransferases|ATAC complex|SAGA complex|GCN5 related N-acetyltransferases

ATXN7 TRRAP

6.36e-04174021059
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP4 AGAP6

6.36e-04174021291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHS1 PLEKHA6 AGAP4 AGAP6

1.09e-03206404682
GeneFamilyArfGAPs

AGAP4 AGAP6

2.41e-0333402395
GeneFamilyRho GTPase activating proteins|BCH domain containing

DLC1 ARHGAP39

5.47e-0350402721
GeneFamilyAnkyrin repeat domain containing

AGAP4 AGAP6 TP53BP2

1.63e-02242403403
GeneFamilyPHD finger proteins

PHF3 NSD1

1.69e-029040288
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ASXL1 DLC1 PHF3 SIPA1L1 NUMB ATP13A3 PPIP5K2 ZBTB11 ZZEF1 TRRAP TRIP12 PICALM NUP153 WWC1 MRTFA TP53BP2

1.64e-108566416M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

DLC1 PHF3 NUMB ATP13A3 TRRAP TRIP12 PICALM NUP153 WWC1 TP53BP2

1.84e-074666410M13522
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

ASXL1 PHF3 ATP13A3 PPIP5K2 USP1 USP6NL NUP153 WWC1

6.81e-07300648M8702
CoexpressionZHENG_BOUND_BY_FOXP3

ASXL1 TBC1D4 ATXN7 MLLT3 PTPN22 USP6NL NUP153 MRTFA

2.80e-05498648M1741
CoexpressionZHENG_BOUND_BY_FOXP3

ASXL1 TBC1D4 ATXN7 MLLT3 PTPN22 USP6NL NUP153 MRTFA

3.17e-05507648MM1030
CoexpressionGSE6269_FLU_VS_E_COLI_INF_PBMC_UP

SZT2 NUP62 USP1 ADAR MRTFA

5.11e-05164645M5653
CoexpressionGINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN

SZT2 ATXN7 NUP62 NUP214 TRRAP

8.80e-05184645M19988
CoexpressionGSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP

TCF4 NSD1 NUP214 ZZEF1 USP6NL

1.18e-04196645M4244
CoexpressionGSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP

SZT2 PHF3 PTPN22 ARHGAP39 MRTFA

1.27e-04199645M9850
CoexpressionGSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN

SZT2 ATXN7 NSD1 NUMB USP6NL

1.30e-04200645M9472
CoexpressionGSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP

STRADB TBC1D4 MGA USP6NL WWC1

1.30e-04200645M9495
CoexpressionGSE14308_TH2_VS_NAIVE_CD4_TCELL_DN

PLEKHS1 ZZEF1 TRRAP USP6NL MRTFA

1.30e-04200645M3365
CoexpressionGSE27786_BCELL_VS_NKCELL_UP

CEP68 TCF4 SZT2 ZBTB11 MGA

1.30e-04200645M4805
CoexpressionGSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP

CEP68 HOXD11 TEX2 ADAR NUP153

1.30e-04200645M9030
CoexpressionGSE21380_NON_TFH_VS_TFH_CD4_TCELL_DN

CEP68 NHSL2 PTPN22 ADAR TP53BP2

1.30e-04200645M7502
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_200

DLC1 NHSL2 PHF3 VCAN NSD1 MYOCD

1.05e-0778626gudmap_developingLowerUrinaryTract_e14.5_ bladder_200_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#3_top-relative-expression-ranked_100

DLC1 VCAN NSD1 MYOCD

2.86e-0634624gudmap_developingLowerUrinaryTract_e14.5_ bladder_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500

DLC1 NHSL2 PHF3 VCAN NSD1 MYOCD ATP13A3

4.87e-06231627gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_200

DLC1 NHSL2 PHF3 VCAN NSD1 MYOCD

1.06e-05171626gudmap_developingLowerUrinaryTract_e14.5_ bladder_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

DLC1 PHF3 VCAN NSD1 MYOCD ATP13A3 NUP214 TRIP12

1.15e-05369628DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000

CEP68 TCF4 TBC1D4 SZT2 TLE2 SIPA1L1 VCAN ATP13A3 NUP214 ARHGAP39 WNK4

1.39e-057796211gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

DLC1 NHSL2 PHF3 VCAN NSD1 MYOCD ATP13A3 NUP214

1.95e-05397628gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500

DLC1 PHF3 VCAN NSD1 MYOCD ATP13A3

2.16e-05194626DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500
CoexpressionAtlaskidney_e13.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_200

HOXD11 VCAN RAI2

4.03e-0523623gudmap_kidney_e13.5_Podocyte_MafB_k4_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_100

DLC1 VCAN NSD1 MYOCD

1.02e-0483624gudmap_developingLowerUrinaryTract_e14.5_ bladder_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000

DLC1 PHF3 VCAN ESRRG NSD1 MLLT3 MYOCD ATP13A3 NUP214 TRIP12

1.06e-048066210DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000

PHF3 ESRRG NSD1 ATP13A3 NUP214 MGA WWC1

1.15e-04379627gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_500

DLC1 PHF3 VCAN NSD1 MYOCD

1.21e-04165625DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_500
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_500

TBC1D4 TLE2 SIPA1L1 VCAN ATP13A3 NUP214 WNK4

1.63e-04401627gudmap_developingKidney_e15.5_Cap mesenchyme_500
CoexpressionAtlaskidney_P1_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_200

HOXD11 VCAN RAI2

1.72e-0437623gudmap_kidney_P1_CapMes_Crym_k2_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500

DLC1 PHF3 VCAN ESRRG NSD1 MYOCD ATP13A3

1.82e-04408627DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500

DLC1 NHSL2 PHF3 VCAN NSD1 MYOCD ATP13A3

2.20e-04421627gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000

PHF3 VCAN ESRRG MYOCD ATP13A3 NUP214

2.95e-04312626gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500

DLC1 PHF3 VCAN ATP13A3 NUP214

3.61e-04209625gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

DLC1 PHF3 VCAN NSD1 MYOCD ATP13A3

3.98e-04330626DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

PHF3 ESRRG NSD1 MYOCD ATP13A3 NUP214 MGA WNK4 WWC1

4.73e-04795629gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

SZT2 PHF3 SIPA1L1 VCAN ESRRG MLLT3 MYOCD ATP13A3 NUP214

5.23e-04806629gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ASXL1 ATP13A3 ZBTB11 NUP153 MRTFA TP53BP2

3.51e-07193646dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ESRRG MUC16 PLEKHS1 MUC5B SH3BP4

5.63e-06177645a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ESRRG MUC16 PLEKHS1 MUC5B SH3BP4

5.63e-06177645363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

ESRRG MYOCD SORBS1 ATP13A3 ALPK2

6.44e-06182645287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC16 PLEKHS1 MUC5B PLEKHA6 MUC3A

6.79e-06184645d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD SORBS1 ALPK2

7.74e-061896455e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

ESRRG MYOCD SORBS1 PICALM ALPK2

7.94e-0619064593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 HOXD11 VCAN MYOCD SORBS1

7.94e-0619064570c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD SORBS1 ALPK2

7.94e-06190645fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A3 ZBTB11 ALPK2 NUP153 MRTFA

8.35e-061926453f925a80b5e2b0577d573e88598a2984a5f6a789
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SIPA1L1 ATP13A3 PLEKHA6 PICALM MRTFA

8.56e-06193645779276e775cb2492e8dd36436295a536084a6415
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ESRRG MYOCD SORBS1 ATP13A3 ALPK2

8.56e-06193645dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD SORBS1 ALPK2

8.78e-06194645c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

TBC1D4 ESRRG MYOCD SORBS1 ALPK2

9.00e-06195645f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

TBC1D4 ESRRG MYOCD SORBS1 ALPK2

9.00e-0619564575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TCF4 MUC16 PLEKHS1 MUC5B SH3BP4

9.00e-06195645b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ESRRG MUC16 PLEKHS1 MUC5B SH3BP4

9.69e-06198645af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B WNK4 WWC1 SH3BP4

9.93e-06199645f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ESRRG MUC16 MUC5B WWC1 SH3BP4

1.02e-052006450eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ESRRG MUC16 PLEKHS1 MUC5B SH3BP4

1.02e-0520064585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ESRRG MYOCD SORBS1 ALPK2

2.88e-051226441cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5B MUC3A WNK4 WWC1

8.29e-05160644028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5B MUC3A WNK4 WWC1

8.29e-051606441f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

ZNF438 SZT2 SORBS1 MGA

8.70e-05162644810881210e015c788814e4fe8d7a24c929cf2621
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

MUC16 PLEKHS1 MUC5B PLEKHA6

9.12e-051646446e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

EBF2 TBC1D4 TMTC3 PHF3

9.78e-05167644ced6ed9b412739c6ced622523347c10295edbf53
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TCF4 SIPA1L1 ATP13A3 ALPK2

1.05e-04170644cc66ac6846c58be9493eb270644ee3ce0f86cfea
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MLLT3 MYOCD SORBS1 RAI2

1.15e-041746447fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC16 PLEKHS1 MUC5B CDON

1.15e-041746447d2f802f493f19a068e097b2909a9000e2160266
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 DLC1 MYOCD SORBS1

1.17e-041756441125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCF4 NHSL2 ESRRG ATP13A3

1.20e-0417664477516048aefbe1f48e825052756df0c310c1c486
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D4 ESRRG WNK4 SH3BP4

1.25e-041786444df6218b20c2f076c22346d23260964cc0d73e65
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBC1D4 ESRRG SH3BP4

1.28e-04179644e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESRRG PLEKHA6 ALPK2 WWC1

1.31e-04180644358923e4228035a3e90e2957392089219e90dcd7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 ASXL1 TBC1D4 SH3BP4

1.33e-0418164430729f0364f719c044712a51453e22dc2c1a232b
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 TCF4 DLC1 MUC3A

1.36e-04182644e67f3234165199085c793915ebb1f9bbd845e933
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MLLT3 PLEKHS1 WWC1 SH3BP4

1.36e-04182644215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRADB ESRRG MLLT3 ALPK2

1.36e-04182644edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESRRG PLEKHA6 ALPK2 WWC1

1.39e-041836446878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC16 MUC5B PLEKHA6 MUC3A

1.39e-0418364415d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

EBF2 TBC1D4 ESRRG SH3BP4

1.39e-041836445c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VCAN NUMB NUP62 ATP13A3

1.42e-04184644857ca1fc4de07b300839b22924211dc624453841
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD SORBS1

1.42e-04184644ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PLEKHS1 MUC5B MUC6

1.42e-0418464401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESRRG MYOCD SORBS1 ALPK2

1.45e-04185644549eeb521c3985bff396ea0f202db21822efa51f
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

ASXL1 TBC1D4 ATP13A3 PICALM

1.45e-04185644e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESRRG PLEKHA6 ALPK2 WWC1

1.45e-041856441bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VCAN MYOCD SORBS1 MRTFA

1.45e-04185644e58a009aaf342be019a909747b1895d5987d4daf
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD SORBS1

1.45e-041856446baccb26f999145e51b91d94315bf8d4655bef31
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ESRRG MUC16 PLEKHS1 MUC5B

1.48e-04186644219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ESRRG MUC16 PLEKHS1 MUC5B

1.48e-04186644ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBC1D4 ESRRG SH3BP4

1.48e-04186644a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

TCF4 TBC1D4 TEX2 SH3BP4

1.48e-04186644916f2aeea4989ba7a29e071e348a51010f010223
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

TCF4 TBC1D4 TEX2 SH3BP4

1.48e-0418664445f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 HOXD11 VCAN MYOCD

1.51e-04187644173f029dcf32af008f517912f6d110a33a9e98cf
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD ALPK2

1.51e-0418764478cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ESRRG MYOCD SORBS1 ALPK2

1.54e-041886446d249fe92d51a19da19ec14bb2262d394255d577
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBC1D4 ESRRG SH3BP4

1.54e-04188644e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD ALPK2

1.57e-041896449c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ESRRG MYOCD SORBS1 ALPK2

1.57e-041896440a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

EBF2 DLC1 MYOCD SORBS1

1.61e-04190644918ad5037881212008f9f69d5df5da91fd01422c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PLEKHS1 MUC5B MUC6

1.61e-0419064423f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 DLC1 MYOCD SORBS1

1.61e-041906445681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PLEKHS1 MUC5B MUC6

1.61e-041906443c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

ASXL1 TBC1D4 ATP13A3 PICALM

1.64e-041916443ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellcellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 PLEKHS1 MUC5B SH3BP4

1.64e-0419164430e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCellcellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 PLEKHS1 MUC5B SH3BP4

1.64e-0419164441d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

ESRRG MYOCD SORBS1 ALPK2

1.64e-041916445d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 HOXD11 VCAN SORBS1

1.64e-04191644107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 HOXD11 VCAN SORBS1

1.64e-04191644bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PLEKHS1 MUC5B SH3BP4

1.67e-04192644c227ab1914191e839fc39c9adc2080026d4b04fc
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DLC1 MLLT3 SORBS1 WWC1

1.67e-041926441bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PLEKHS1 MUC5B SH3BP4

1.67e-04192644bf187a57a559ab732bb815892af45ca922966ac6
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 PLEKHS1 MUC5B SH3BP4

1.67e-04192644f573b2d205bd4d053a548af3fe3ff9de7be0cd2b
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 PHF3 VCAN TBCK

1.67e-04192644916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EBF2 TBC1D4 ESRRG SH3BP4

1.67e-04192644f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

TBC1D4 ESRRG MYOCD ALPK2

1.67e-04192644ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ASXL1 SORBS1 ATP13A3 NUP153

1.67e-041926446bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 MYOCD SORBS1 CDON

1.67e-04192644d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 PHF3 VCAN TBCK

1.71e-04193644e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 MYOCD SORBS1 CDON

1.71e-041936440256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellCF-Lymphoid|CF / Disease state, Lineage and Cell class

TCF4 ASXL1 TBCK PTPN22

1.71e-0419364411de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

EBF2 TCF4 VCAN MRTFA

1.74e-0419464411c79a8c56ece42713b04b321982e41e239f07a5
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

EBF2 TCF4 VCAN MRTFA

1.74e-04194644234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 VCAN MYOCD SORBS1

1.74e-04194644ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 VCAN MYOCD SORBS1

1.77e-0419564449c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 PLEKHA6 MUC3A CDON

1.77e-04195644d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ESRRG PLEKHS1 MUC5B WWC1

1.77e-0419564421dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 PLEKHA6 MUC3A CDON

1.77e-0419564419853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 VCAN MYOCD SORBS1

1.77e-04195644dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

EBF2 TCF4 VCAN MRTFA

1.77e-04195644ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 PLEKHS1 MUC5B WWC1

1.77e-04195644e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF4 HOXD11 VCAN MYOCD

1.81e-04196644a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

SIPA1L1 VCAN NUMB PICALM

1.81e-0419664404d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 HOXD11 VCAN SORBS1

1.81e-04196644fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLC1 HOXD11 VCAN SORBS1

1.81e-04196644802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn|World / Primary Cells by Cluster

TCF4 VCAN MLLT3 SORBS1

1.81e-041966449401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCelltumor_Lung-Myeloid_cells-Monocytes|tumor_Lung / Location, Cell class and cell subclass

VCAN NUMB ATP13A3 NUP214

1.81e-041966444a00c416688ae06ed2aef19626a485f646925d67
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 TCF4 LINC01600 VCAN

1.84e-041976446806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 TLE2 MUC5B WNK4

1.84e-04197644e14a0e8a893c72356afc5508e3531ae0b23bfe16
DrugHydroflumethiazide [135-09-1]; Up 200; 12uM; MCF7; HT_HG-U133A

CEP68 HOXD11 PHF3 MCM3AP PLEKHA6 MRTFA CDON

1.16e-061966371687_UP
DrugAlthiazide [5588-16-9]; Up 200; 10.4uM; MCF7; HT_HG-U133A

SZT2 VCAN PLEKHS1 NUP214 PLEKHA6 MRTFA CDON

1.20e-061976376829_UP
DrugNitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A

SZT2 SIPA1L1 NUP214 MUC6 USP6NL CDON

1.52e-051926363087_UP
DrugClonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A

EBF2 PHF3 VCAN ESRRG MUC6 CDON

1.75e-051976364478_UP
Drug(S)-(-)-Atenolol [93379-54-5]; Down 200; 15uM; PC3; HT_HG-U133A

VCAN SORBS1 NUP214 ZZEF1 MRTFA CDON

1.80e-051986366725_DN
DrugNialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A

SZT2 VCAN ESRRG NUP214 MRTFA CDON

1.80e-051986364525_UP
DrugSulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

DLC1 VCAN SORBS1 NUP214 RAI2 CDON

1.86e-051996364389_UP
Drugtitanium silicate

DYM NSD1

4.51e-054632CID011600682
DrugNexus

TBC1D4 VCAN NUMB MYOCD NUP153

6.39e-05152635CID000098527
DrugMethylergometrine maleate [113-42-8]; Up 200; 8.8uM; HL60; HG-U133A

TCF4 SIPA1L1 VCAN PTPN22 PICALM

9.97e-051676351607_UP
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

DLC1 PTPN22 PLEKHA6 MRTFA CDON

1.53e-041836355221_UP
DrugRifabutin [72559-06-9]; Up 200; 4.8uM; PC3; HT_HG-U133A

CEP68 VCAN ESRRG MLLT3 RAI2

1.57e-041846354527_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

VCAN ESRRG MLLT3 SORBS1 RAI2

1.65e-041866356671_UP
DrugTadjakonine [11087-94-8]; Up 200; 7.4uM; PC3; HT_HG-U133A

TCF4 ESRRG MCM3AP ATP13A3 NUP214

2.01e-041946354599_UP
DrugErgocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A

CEP68 MLLT3 PTPN22 NUP214 MRTFA

2.01e-041946354552_UP
DrugNiridazole [61-57-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A

SZT2 TLE2 PTPN22 MUC5B NUP214

2.01e-041946353301_UP
DrugNaringenine [480-41-1]; Down 200; 14.6uM; MCF7; HT_HG-U133A

MUC5B NUP214 PLEKHA6 MUC6 MRTFA

2.01e-041946354422_DN
Drugphentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA

TBC1D4 PHF3 NUMB NUP214 ZZEF1

2.06e-041956351138_DN
Drug3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; PC3; HT_HG-U133A

TCF4 ATXN7 PHF3 TLE2 MCM3AP

2.06e-041956354664_DN
DrugOxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A

DLC1 VCAN PTPN22 MRTFA CDON

2.06e-041956354124_UP
DrugVancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A

SZT2 PHF3 MUC5B MUC6 MRTFA

2.11e-041966354423_DN
DrugMolindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A

DLC1 VCAN MCM3AP PICALM MRTFA

2.11e-041966354784_UP
DrugCefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; HL60; HT_HG-U133A

EBF2 DLC1 ZZEF1 MUC6 CDON

2.11e-041966352735_UP
DrugGuanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

SZT2 TLE2 PLEKHS1 SORBS1 NUP214

2.11e-041966353171_UP
DrugBetamethasone [378-44-9]; Down 200; 10.2uM; PC3; HT_HG-U133A

TCF4 TLE2 VCAN MUC5B MRTFA

2.11e-041966356728_DN
DrugEpicatechin-(-) [154-23-4]; Down 200; 13.8uM; MCF7; HT_HG-U133A

TBC1D4 DLC1 NUMB PTPN22 MUC5B

2.11e-041966354419_DN
DrugSisomicin sulfate [53179-09-2]; Down 200; 2.8uM; HL60; HT_HG-U133A

CEP68 TCF4 VCAN ATP13A3 MRTFA

2.11e-041966352493_DN
Drug0173570-0000 [211245-44-2]; Up 200; 1uM; MCF7; HT_HG-U133A

TCF4 PLEKHS1 MUC5B NUP214 MRTFA

2.16e-041976354715_UP
DrugEthisterone [434-03-7]; Up 200; 12.8uM; HL60; HT_HG-U133A

SZT2 PHF3 VCAN PTPN22 MUC6

2.16e-041976352366_UP
Drugdeferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A

CEP68 TCF4 TBC1D4 DLC1 MCM3AP

2.16e-04197635460_DN
DrugAmidopyrine [58-15-1]; Up 200; 17.2uM; MCF7; HT_HG-U133A

DLC1 MUC5B SORBS1 ATP13A3 MRTFA

2.16e-041976352222_UP
DrugSulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A

EBF2 PLEKHS1 SORBS1 NUP214 MUC6

2.16e-041976355098_UP
DrugICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A

DLC1 PHF3 SIPA1L1 MUC6 USP6NL

2.16e-041976352698_UP
Drug5155877; Down 200; 10uM; MCF7; HT_HG-U133A

CEP68 MUC5B ATP13A3 TRRAP PICALM

2.16e-041976356549_DN
DrugVancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; PC3; HT_HG-U133A

TBC1D4 ATXN7 ESRRG NUP214 MRTFA

2.16e-041976354598_UP
DrugCyclopentolate hydrochloride [5870-29-1]; Up 200; 12.2uM; PC3; HT_HG-U133A

HOXD11 SZT2 ATXN7 SORBS1 NUP214

2.16e-041976355734_UP
DrugGliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A

PHF3 NUMB ATP13A3 USP6NL WWC1

2.16e-041976352870_DN
DrugDicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; PC3; HT_HG-U133A

EBF2 DLC1 PTPN22 SORBS1 MRTFA

2.16e-041976356666_UP
DrugD-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A

TCF4 SZT2 PLEKHS1 ZZEF1 MUC6

2.16e-041976353562_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; MCF7; HT_HG-U133A

DLC1 SZT2 SIPA1L1 MUC5B MRTFA

2.16e-041976355009_UP
DrugEthamivan [304-84-7]; Up 200; 18uM; PC3; HT_HG-U133A

CEP68 TCF4 TBC1D4 PHF3 WWC1

2.16e-041976357260_UP
DrugProglumide [6620-60-6]; Down 200; 12uM; PC3; HT_HG-U133A

VCAN ESRRG MUC5B PICALM MRTFA

2.16e-041976354337_DN
DrugGlycopyrrolate [596-51-0]; Down 200; 10uM; HL60; HT_HG-U133A

CEP68 DLC1 VCAN MRTFA CDON

2.16e-041976352565_DN
DrugBetonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A

EBF2 TCF4 PHF3 PLEKHS1 SORBS1

2.21e-041986354301_UP
Drugestradiol, USP; Up 200; 0.01uM; PC3; HT_HG-U133A

SZT2 PHF3 TLE2 PLEKHA6 RAI2

2.21e-041986351241_UP
DrugTrimethadione [127-48-0]; Down 200; 28uM; HL60; HT_HG-U133A

TCF4 DLC1 NUP214 USP6NL WWC1

2.21e-041986352486_DN
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A

VCAN MCM3AP ZZEF1 MRTFA CDON

2.21e-041986355214_UP
DrugMethoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A

PHF3 PTPN22 MUC5B SORBS1 ZZEF1

2.21e-041986352848_UP
DrugFoliosidine [2520-38-9]; Up 200; 13uM; MCF7; HT_HG-U133A

DLC1 ESRRG MUC5B MRTFA CDON

2.26e-041996353636_UP
DrugIsocarboxazid [59-63-2]; Down 200; 17.2uM; HL60; HT_HG-U133A

TCF4 TBC1D4 SZT2 PHF3 SIPA1L1

2.26e-041996352562_DN
DrugBudesonide [51333-22-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A

DLC1 PLEKHS1 SORBS1 MRTFA CDON

2.26e-041996352866_UP
DrugPhenethicillin potassium salt [132-93-4]; Up 200; 10uM; MCF7; HT_HG-U133A

PLEKHS1 MUC5B SORBS1 MUC6 CDON

2.26e-041996356105_UP
DrugPropranolol hydrochloride [318-98-9]; Down 200; 13.6uM; PC3; HT_HG-U133A

TCF4 TLE2 VCAN ATP13A3 NUP214

2.26e-041996356759_DN
DrugMefenamic acid [61-68-7]; Down 200; 16.6uM; MCF7; HT_HG-U133A

DLC1 HOXD11 PHF3 NUMB CDON

2.26e-041996355534_DN
DrugDesipramine hydrochloride [58-28-6]; Down 200; 13.2uM; PC3; HT_HG-U133A

VCAN ESRRG MUC5B PLEKHA6 RAI2

2.26e-041996356693_DN
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

DLC1 TLE2 MUC6 USP6NL MRTFA

2.26e-041996352677_UP
DrugSelegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; PC3; HT_HG-U133A

PHF3 ESRRG MCM3AP MLLT3 MRTFA

2.26e-041996354065_UP
DrugCytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A

TLE2 MCM3AP PLEKHS1 NUP214 ZZEF1

2.26e-041996356217_UP
DrugLoxapine succinate [27833-64-3]; Up 200; 9uM; HL60; HG-U133A

TBC1D4 ATXN7 ATP13A3 TRRAP PICALM

2.31e-042006352016_UP
DrugPHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT_HG-U133A

DLC1 HOXD11 PHF3 PLEKHS1 PTPN22

2.31e-042006353773_UP
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC3A MUC6

1.16e-0564644DOID:4947 (is_marker_for)
DiseaseSTRIATONIGRAL DEGENERATION, INFANTILE (disorder)

NUP62 ADAR

1.39e-053642C0795996
Diseaseacute myeloid leukemia (is_implicated_in)

ASXL1 NSD1 NUP214 PICALM

3.41e-0584644DOID:9119 (is_implicated_in)
Diseasecholelithiasis

ZNF438 NSD1 ADAR SH3BP4

4.09e-0588644EFO_0004799
Diseasecerebral palsy (implicated_via_orthology)

AGAP4 AGAP6

2.06e-0410642DOID:1969 (implicated_via_orthology)
DiseaseMetastatic melanoma

STRADB WNK4 ALPK2

2.23e-0454643C0278883
Diseasenucleus accumbens volume change measurement

MUC16 WWC1

2.52e-0411642EFO_0021493
DiseaseMicrocephaly

TCF4 NUP214 TRRAP

4.22e-0467643C0025958
Diseasecutaneous Leishmaniasis

TCF4 DYM

5.45e-0416642EFO_0005046
Diseaseelectroencephalogram measurement

DBX1 MLLT3 SH3BP4

5.65e-0474643EFO_0004357
DiseaseAcute myeloid leukemia

NUP214 PICALM

6.17e-0417642cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

NUP214 PICALM

6.17e-0417642601626
Diseasenose morphology measurement

TCF4 DLC1 DBX1 MLLT3 SORBS1

7.44e-04329645EFO_0007843
Diseasecarpal tunnel syndrome

ZNF438 VCAN MRTFA

9.68e-0489643EFO_0004143
Diseasesocial interaction measurement

TCF4 SIPA1L1 USP1

1.13e-0394643EFO_0009592
DiseaseAdenocarcinoma of large intestine

DLC1 TBCK TRRAP

1.20e-0396643C1319315
DiseaseFEV/FEC ratio

ZNF438 ASXL1 DLC1 ESRRG TBCK NSD1 MGA MRTFA CDON

1.28e-031228649EFO_0004713
DiseaseAdenoid Cystic Carcinoma

VCAN NSD1 MGA

1.35e-03100643C0010606
Diseasegallstones

ADAR NUP153 SH3BP4

1.69e-03108643EFO_0004210
DiseaseOvarian Mucinous Adenocarcinoma

TRRAP WNK4

2.07e-0331642C1335167

Protein segments in the cluster

PeptideGeneStartEntry
SICFSPSISSTTSPK

AGAP4

351

Q96P64
TFAKLSSQTPSSPLT

VCAN

2816

P13611
LDSFSVSPASTLKSP

CEP68

336

Q76N32
FVGTTAFSPLSSKST

ADGRG4

1671

Q8IZF6
KPPSSSSSSAKTLAF

ALPK2

1641

Q86TB3
SVASPFTSKTPSISC

ATP13A3

906

Q9H7F0
SSSEALFKSFSSAPP

MLLT3

301

P42568
STSSILPFSSSVFPA

EBF2

521

Q9HAK2
SISSFTFTGPTPFKI

LINC01600

86

Q96MT4
SVPSYPSKSASVTAS

TP53BP2

766

Q13625
STSFNYSSSSPTFPK

ASXL1

1451

Q8IXJ9
SICFSPSISSTTSPK

AGAP6

351

Q5VW22
STATKSTATSFTPIP

MUC5B

3056

Q9HC84
STATSFTPIPSFTLG

MUC5B

3061

Q9HC84
TATKSTATSFTPIPS

MUC5B

4741

Q9HC84
SESKFSSSFPKPPSS

RAI2

256

Q9Y5P3
TSKPSKPLLFSSASS

NSD1

881

Q96L73
KSSSTPFPFRTGLTS

PAAT

251

Q9H8K7
SSCVFPTFTLRKPSS

ARHGAP39

676

Q9C0H5
VFPSSLLPTSSTSLF

PTPN22

561

Q9Y2R2
PLTATEPTSSLATSF

MUC16

2651

Q8WXI7
TPVSASSSPSKAFAS

MUC16

2861

Q8WXI7
SSSPSKAFASLTTAP

MUC16

2866

Q8WXI7
SSFPTDTSFLLSKVP

MUC16

5201

Q8WXI7
SSPAMTSTSFFSTLP

MUC16

8566

Q8WXI7
PSSFSTAKTSTSLPY

MUC6

1906

Q6W4X9
STISPSTSYSLKPHS

MGA

876

Q8IWI9
SSSSSLESSSFPLPK

WWC1

261

Q8IX03
YPSSKPATSTFPSSF

TCF4

201

P15884
FLVPKSTTSSSAFSP

KIAA2026

1321

Q5HYC2
FPTSPTSTAKQEFLT

KIAA1109

2851

Q2LD37
SFKSPTSVGAFPSTS

MCM3AP

111

O60318
FPSSTATFPETTTLT

MUC3A

976

Q02505
PTAFSPASETTFLKF

DBX1

96

A6NMT0
TSTPSASGQFSKPFS

NUP214

1201

P35658
FTFGTAKTATTTPAT

NUP62

16

P37198
AKTATTTPATGFSFS

NUP62

21

P37198
PPTSVFSFFPSLSKS

ATXN7

181

O15265
SIPSPTFSKSSSAIS

MYOCD

701

Q8IZQ8
SRSPTAVLTKPSASF

MYOCD

771

Q8IZQ8
TPGFSALTTSSPSIF

MYOCD

901

Q8IZQ8
TSTTAPTFQPVFSSM

POM121C

741

A8CG34
STPTFNIPFGSSAKS

POM121C

921

A8CG34
TSASPSTDSASKPAF

POM121B

406

A6NF01
TPTPSATSFFSGKSP

ADAR

601

P55265
LLSFSFPAPTSSSEL

DYM

36

Q7RTS9
SSFIKTEPSSPASLT

ESRRG

36

P62508
FTKTNSTFSSSPPPV

CDON

1121

Q4KMG0
SDFASKPSFLSQPSS

HOXD11

26

P31277
EASSATTSPFFKPPA

NUMB

566

P49757
LFPPHSTSTKDSFST

SZT2

871

Q5T011
TSSSFFTGLKSPAPE

SH3BP4

261

Q9P0V3
STAPSSLVFTPFASS

NHSL2

941

Q5HYW2
SASPVVFTSARSSPK

SIPA1L1

1431

O43166
PYSSSKDSSPTLASK

SIPA1L1

1726

O43166
SFGSLPSPKELSSFS

DLC1

636

Q96QB1
SLAPLSTTAPSLFST

MRTFA

901

Q969V6
IFSTPSSSNSTSKLP

PICALM

376

Q13492
FIKSPPSQLFSSVTS

PLEKHS1

21

Q5SXH7
SSASLTSPLSPFSLV

PLEKHA6

696

Q9Y2H5
EPSSSPSKVSNKFTF

USP6NL

591

Q92738
LSNFTSSPTTASKPA

ZBTB11

156

O95625
FPSVSKPSSAYPSTT

SORBS1

291

Q9BX66
CPSEFPSKSITFTSR

PHF3

1771

Q92576
SLPITSSSLPTFNFS

NUP153

476

P49790
SSSLPTFNFSSPEIT

NUP153

481

P49790
TPFTKPASLFSSSLR

TBCK

281

Q8TEA7
TSFSAPSFTAPSFLK

TBC1D4

701

O60343
SLSPGSTDFSTFLSP

ZZEF1

436

O43149
HTPSSKTFSPAFFSL

STRADB

331

Q9C0K7
TSSPVSPKSLAFTSS

PPIP5K2

1011

O43314
SSSFIEPIFPTSKIS

TMTC3

821

Q6ZXV5
SPLTSPSDTRSFFKV

TEX2

266

Q8IWB9
PTTTQSPKSSFLASL

TRIP12

1031

Q14669
SPLTLSSPFTTSFSL

TLE2

341

Q04725
SSSPKPSSVFRNGFS

ZNF438

486

Q7Z4V0
SIFPTEPSTSSVASK

TRRAP

2221

Q9Y4A5
TFSPTCSQVTLSSPF

WNK4

891

Q96J92
KDFLNSLSPSTSPTS

USP1

761

O94782