Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

ALG10B ALG10

3.35e-0521162GO:0106073
GeneOntologyMolecularFunctionbeta-adrenergic receptor activity

ADRB1 ADRB3

1.99e-0441162GO:0004939
GeneOntologyMolecularFunctionhyaluronan synthase activity

HAS1 HAS3

1.99e-0441162GO:0050501
GeneOntologyBiologicalProcessaminoglycan biosynthetic process

ST3GAL3 B3GNT8 CHST13 B3GNT2 HAS1 HAS3

7.59e-06801216GO:0006023
GeneOntologyBiologicalProcessaminoglycan metabolic process

ST3GAL3 CEMIP2 B3GNT8 CHST13 B3GNT2 HAS1 HAS3

1.29e-051321217GO:0006022
GeneOntologyBiologicalProcessmucopolysaccharide metabolic process

ST3GAL3 CEMIP2 CHST13 B3GNT2 HAS1 HAS3

2.74e-051001216GO:1903510
GeneOntologyBiologicalProcessglycosaminoglycan metabolic process

ST3GAL3 CEMIP2 CHST13 B3GNT2 HAS1 HAS3

7.98e-051211216GO:0030203
GeneOntologyBiologicalProcessglycosaminoglycan biosynthetic process

ST3GAL3 CHST13 B3GNT2 HAS1 HAS3

8.47e-05761215GO:0006024
GeneOntologyBiologicalProcessnorepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure

ADRB1 ADRB3

1.02e-0431212GO:0002025
DomainAlg10

ALG10B ALG10

4.03e-0521192IPR016900
DomainMed12

MED12L MED12

4.03e-0521192PF09497
DomainMediator_Med12_catenin-bd

MED12L MED12

4.03e-0521192IPR021989
DomainMed12-PQL

MED12L MED12

4.03e-0521192PF12144
DomainMed12-LCEWAV

MED12L MED12

4.03e-0521192PF12145
DomainMed12

MED12L MED12

4.03e-0521192SM01281
DomainMediator_Med12

MED12L MED12

4.03e-0521192IPR019035
DomainDIE2_ALG10

ALG10B ALG10

4.03e-0521192PF04922
DomainMediator_Med12_LCEWAV

MED12L MED12

4.03e-0521192IPR021990
DomainHAS/NodC

HAS1 HAS3

1.20e-0431192IPR026107
DomainRequiem/DPF_N_dom

DPF1 DPF2

1.20e-0431192IPR025750
DomainRequiem_N

DPF1 DPF2

1.20e-0431192PF14051
DomainDHC_N1

DNAH2 DNAH11

1.10e-0381192PF08385
DomainDynein_heavy_dom-1

DNAH2 DNAH11

1.10e-0381192IPR013594
DomainADR_fam

ADRB1 ADRB3

1.75e-03101192IPR002233
DomainAAA

DNAH2 RFC1 ATAD2B HELZ2 DNAH11

2.30e-031441195SM00382
DomainAAA+_ATPase

DNAH2 RFC1 ATAD2B HELZ2 DNAH11

2.30e-031441195IPR003593
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH11

3.48e-03141192IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH11

3.48e-03141192IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH11

3.48e-03141192IPR013602
DomainDHC_N2

DNAH2 DNAH11

3.48e-03141192PF08393
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH11

3.48e-03141192IPR011704
DomainMT

DNAH2 DNAH11

3.48e-03141192PF12777
DomainAAA_8

DNAH2 DNAH11

3.48e-03141192PF12780
DomainAAA_5

DNAH2 DNAH11

3.48e-03141192PF07728
DomainDHC_fam

DNAH2 DNAH11

4.00e-03151192IPR026983
DomainDynein_heavy

DNAH2 DNAH11

4.00e-03151192PF03028
DomainDynein_heavy_dom

DNAH2 DNAH11

4.00e-03151192IPR004273
DomainGRAM

TBC1D9B TBC1D9

4.56e-03161192SM00568
DomainGalactosyl_T

B3GNT8 B3GNT2

4.56e-03161192PF01762
DomainGlyco_trans_31

B3GNT8 B3GNT2

4.56e-03161192IPR002659
DomainGal_mutarotase_SF_dom

MAN2C1 BEST4

5.14e-03171192IPR011013
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

RNF31 ECD BTBD9 RFC1 PNKD NEU1 TRMT2A EBI3 P3H2 HERC2 CDC27

1.14e-056041241138803224
Pubmed

Enhanced inflammation and accelerated wound closure following tetraphorbol ester application or full-thickness wounding in mice lacking hyaluronan synthases Has1 and Has3.

HAS1 HAS3

1.26e-052124221850020
Pubmed

ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) polymorphism in ARDB1.

ADRB1 ADRB3

1.26e-052124229587766
Pubmed

Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7.

EVX1 EVX2

1.26e-05212421684419
Pubmed

Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.

HAS1 HAS3

1.26e-052124214724275
Pubmed

Functional beta-adrenergic receptor signalling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes.

ADRB1 ADRB3

1.26e-052124216631628
Pubmed

Transforming Growth Factor-β Receptor-Mediated, p38 Mitogen-Activated Protein Kinase-Dependent Signaling Drives Enhanced Myofibroblast Differentiation during Skin Wound Healing in Mice Lacking Hyaluronan Synthases 1 and 3.

HAS1 HAS3

1.26e-052124236063901
Pubmed

Hyaluronan metabolism in human keratinocytes and atopic dermatitis skin is driven by a balance of hyaluronan synthases 1 and 3.

HAS1 HAS3

1.26e-052124224658508
Pubmed

Endogenously expressed Trp1 is involved in store-mediated Ca2+ entry by conformational coupling in human platelets.

TRPC1 ITPR1

1.26e-052124212196544
Pubmed

Activation of beta1,3-N-acetylglucosaminyltransferase-2 (beta3Gn-T2) by beta3Gn-T8. Possible involvement of beta3Gn-T8 in increasing poly-N-acetyllactosamine chains in differentiated HL-60 cells.

B3GNT8 B3GNT2

1.26e-052124218826941
Pubmed

Knockout of hyaluronan synthase 1, but not 3, impairs formation of the retrocalcaneal bursa.

HAS1 HAS3

1.26e-052124229672913
Pubmed

Association of β1 and β3 adrenergic receptors gene polymorphisms with insulin resistance and high lipid profiles related to type 2 diabetes and metabolic syndrome.

ADRB1 ADRB3

1.26e-052124224972470
Pubmed

Structure and expression of two members of the d4 gene family in mouse.

DPF1 DPF2

1.26e-052124210602997
Pubmed

Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling.

ADRB1 ADRB3

1.26e-052124222306453
Pubmed

Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase.

TGFB1I1 MMP14

1.26e-052124226769900
Pubmed

The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ hematoendothelial progenitors.

CEMIP2 HAS1 HAS3

2.39e-0516124333454424
Pubmed

[The genotype analysis of beta adrenergic receptor gene family in high risk population of hypertension in northeast China].

ADRB1 ADRB3

3.77e-053124215079793
Pubmed

Expression of hyaluronan synthase genes in umbilical cord blood stem/progenitor cells.

HAS1 HAS3

3.77e-053124216564133
Pubmed

Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy.

ADRB1 ADRB3

3.77e-053124218801900
Pubmed

Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex.

DPF1 DPF2

3.77e-053124218765789
Pubmed

Mammalian hyaluronan synthases: investigation of functional relationships in vivo.

HAS1 HAS3

3.77e-053124210093717
Pubmed

Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice.

ADRB1 ADRB3

3.77e-053124228752049
Pubmed

Differential expression and role of hyperglycemia induced oxidative stress in epigenetic regulation of β1, β2 and β3-adrenergic receptors in retinal endothelial cells.

ADRB1 ADRB3

3.77e-053124224885710
Pubmed

[The relationship between expressions of beta1-, beta2-, beta3-adrenoceptor mRNA of myocardium and cardiac function in patients with heart failure].

ADRB1 ADRB3

3.77e-053124215932670
Pubmed

The d4 gene family in the human genome.

DPF1 DPF2

3.77e-05312428812431
Pubmed

An in situ hybridization study of Hyaluronan synthase (Has) mRNA in developing mouse molar and incisor tooth germs.

HAS1 HAS3

3.77e-053124227289075
Pubmed

Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance.

ADRB1 ADRB3

3.77e-053124219553224
Pubmed

A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).

ALG10B ALG10

3.77e-053124224303013
Pubmed

Hyaluronan Regulates Eyelid and Meibomian Gland Morphogenesis.

HAS1 HAS3

3.77e-053124230046813
Pubmed

TNF-alpha, IFN-gamma, and IL-1beta modulate hyaluronan synthase expression in human skin fibroblasts: synergistic effect by concomital treatment with FeSO4 plus ascorbate.

HAS1 HAS3

3.77e-053124216786194
Pubmed

RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability.

TRPC1 ITPR1

3.77e-053124212766172
Pubmed

Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.

HAS1 HAS3

3.77e-053124225795779
Pubmed

Activation of the Thiazide-Sensitive Sodium-Chloride Cotransporter by Beta3-Adrenoreceptor in the Distal Convoluted Tubule.

ADRB1 ADRB3

3.77e-053124234483955
Pubmed

Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.

HAS1 HAS3

3.77e-053124223303191
Pubmed

Variants in the human beta 1-, beta 2-, and beta 3-adrenergic receptor genes are not associated with morbid obesity in children and adolescents.

ADRB1 ADRB3

3.77e-053124215479221
Pubmed

Genetic characterization of physical activity behaviours in university students enrolled in kinesiology degree programs.

ADRB1 ADRB3

3.77e-053124228177749
Pubmed

betaAR signaling required for diet-induced thermogenesis and obesity resistance.

ADRB1 ADRB3

3.77e-053124212161655
Pubmed

Role of β-adrenoceptors in glucose uptake in astrocytes using β-adrenoceptor knockout mice.

ADRB1 ADRB3

3.77e-053124221138422
Pubmed

Uroguanylin Action in the Brain Reduces Weight Gain in Obese Mice via Different Efferent Autonomic Pathways.

ADRB1 ADRB3

3.77e-053124226566631
Pubmed

Environmental novelty activates β2-adrenergic signaling to prevent the impairment of hippocampal LTP by Aβ oligomers.

ADRB1 ADRB3

3.77e-053124223473322
Pubmed

Adrenergic beta1 receptor polymorphism (Ser49Gly) is associated with obesity in type II diabetic patients.

ADRB1 ADRB3

3.77e-053124218239290
Pubmed

Norepinephrine induces lipolysis in beta1/beta2/beta3-adrenoceptor knockout mice.

ADRB1 ADRB3

3.77e-053124215939797
Pubmed

Hyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis.

HAS1 HAS3

3.77e-053124222654110
Pubmed

Manipulation of hyaluronan synthase expression in prostate adenocarcinoma cells alters pericellular matrix retention and adhesion to bone marrow endothelial cells.

HAS1 HAS3

3.77e-053124211790779
Pubmed

Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy.

ADRB1 ADRB3

3.77e-053124215464701
Pubmed

Control of 4E-BP1 expression in mouse brown adipose tissue by the beta3-adrenoceptor.

ADRB1 ADRB3

3.77e-053124215474034
Pubmed

Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.

ADRB1 ADRB3

3.77e-053124219420258
Pubmed

Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells.

HAS1 HAS3

3.77e-053124211431361
Pubmed

Genetic influences of beta-adrenoceptor polymorphisms on arterial functional changes and cardiac remodeling in hypertensive patients.

ADRB1 ADRB3

3.77e-053124217345787
Pubmed

[Association of beta-adrenoceptor gene polymorphism with resting heart rate].

ADRB1 ADRB3

3.77e-053124217591269
Pubmed

Ghrelin action in the brain controls adipocyte metabolism.

ADRB1 ADRB3

3.77e-053124216767221
Pubmed

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties.

HAS1 HAS3

3.77e-053124210455188
Pubmed

A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate.

ADRB1 ADRB3

3.77e-053124211854867
Pubmed

Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

HAS1 HAS3

3.77e-05312429442026
Pubmed

Interactive effects between polymorphisms in the beta-adrenergic receptors and longitudinal changes in obesity.

ADRB1 ADRB3

3.77e-053124215833937
Pubmed

Expression and functional role of beta-adrenoceptors in the human urinary bladder urothelium.

ADRB1 ADRB3

3.77e-053124218311486
Pubmed

Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space.

HAS1 HAS3

3.77e-053124224790187
Pubmed

A putative beta2-adrenoceptor from the rainbow trout (Oncorhynuchus mykiss). Molecular characterization and pharmacology.

ADRB1 ADRB3

3.77e-053124211737201
Pubmed

Perturbation of hyaluronan synthesis in the trabecular meshwork and the effects on outflow facility.

HAS1 HAS3

3.77e-053124222695958
Pubmed

Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns.

HAS1 HAS3

3.77e-053124215765504
Pubmed

Hyaluronan Modulates the Biomechanical Properties of the Cornea.

HAS1 HAS3

3.77e-053124236478198
Pubmed

Hyaluronan Derived From the Limbus is a Key Regulator of Corneal Lymphangiogenesis.

HAS1 HAS3

3.77e-053124230897620
Pubmed

Expression of β-adrenergic receptor subtypes in human normal and dilated ureter.

ADRB1 ADRB3

3.77e-053124228756611
Pubmed

Association of beta-adrenoceptor single nucleotide polymorphisms with resting heart rate.

ADRB1 ADRB3

3.77e-053124217270896
Pubmed

Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2-adrenergic receptors.

ADRB1 ADRB3

3.77e-053124210358009
Pubmed

Diverse evolutionary histories for beta-adrenoreceptor genes in humans.

ADRB1 ADRB3

3.77e-053124219576569
Pubmed

Expression of beta adrenergic receptors in mouse oocytes and preimplantation embryos.

ADRB1 ADRB3

3.77e-053124215791602
Pubmed

Total beta-adrenoceptor deficiency results in cardiac hypotrophy and negative inotropy.

ADRB1 ADRB3

3.77e-053124220406048
Pubmed

Beta(1)/beta(2)/beta(3)-adrenoceptor knockout mice are obese and cold-sensitive but have normal lipolytic responses to fasting.

ADRB1 ADRB3

3.77e-053124212387862
Pubmed

Regulation of the uncoupling protein gene (Ucp) by beta 1, beta 2, and beta 3-adrenergic receptor subtypes in immortalized brown adipose cell lines.

ADRB1 ADRB3

3.77e-05312427738011
Pubmed

Stress-induced epinephrine levels compromise murine dermal fibroblast activity through β-adrenoceptors.

ADRB1 ADRB3

3.77e-053124221366703
Pubmed

β₁-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β₃-adrenergic receptor-knockout mice via nonshivering thermogenesis.

ADRB1 ADRB3

3.77e-053124221878665
Pubmed

Analysis of hyaluronic acid in the endometrium of women with polycystic ovary syndrome.

HAS1 HAS3

3.77e-053124230614308
Pubmed

Total beta-adrenoceptor knockout slows conduction and reduces inducible arrhythmias in the mouse heart.

ADRB1 ADRB3

3.77e-053124223133676
Pubmed

In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity.

HAS1 HAS3

3.77e-053124210617644
Pubmed

Association between beta-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study.

ADRB1 ADRB3

3.77e-053124215917856
Pubmed

Hyaluronan synthases.

HAS1 HAS3

3.77e-05312429206724
Pubmed

Expression regulation of hyaluronan synthase in corneal endothelial cells.

HAS1 HAS3

3.77e-053124211006212
Pubmed

Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes.

HAS1 HAS3

3.77e-053124224057227
Pubmed

Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility.

ADRB1 ADRB3

3.77e-053124233183171
Pubmed

Hyaluronan in cervical epithelia protects against infection-mediated preterm birth.

HAS1 HAS3

7.53e-054124225384213
Pubmed

Developmental expression of the mouse Evx-2 gene: relationship with the evolution of the HOM/Hox complex.

EVX1 EVX2

7.53e-05412427579515
Pubmed

Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus.

TYRO3 LTK

7.53e-054124214695357
Pubmed

β-Adrenergic receptors control brown adipose UCP-1 tone and cold response without affecting its circadian rhythmicity.

ADRB1 ADRB3

7.53e-054124229715048
Pubmed

β3 adrenergic receptor in the kidney may be a new player in sympathetic regulation of renal function.

ADRB1 ADRB3

7.53e-054124227206969
Pubmed

Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation.

HAS1 HAS3

7.53e-054124228863216
Pubmed

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.

ALG10B ALG10

7.53e-054124214525949
Pubmed

An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation.

ADRB1 ADRB3

7.53e-054124217446185
Pubmed

Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations.

ADRB1 ADRB3

7.53e-054124217512307
Pubmed

Tumor necrosis factor-stimulated gene-6 (TSG-6) amplifies hyaluronan synthesis by airway smooth muscle cells.

HAS1 HAS3

7.53e-054124223129777
Pubmed

Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation.

ADRB1 ADRB3

7.53e-054124218331634
Pubmed

[Myocardial hypertrophy in patients with hypertensive disease: the role of genetic polymorphism of beta-adrenoreactive structures].

ADRB1 ADRB3

7.53e-054124220144152
Pubmed

Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling.

ADRB1 ADRB3

7.53e-054124221976502
Pubmed

Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption.

HAS1 HAS3

7.53e-054124236718364
Pubmed

Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma.

HAS1 HAS3

7.53e-054124223560496
Pubmed

Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality.

ADRB1 ADRB3

7.53e-054124218245567
Pubmed

Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-beta upregulates their expression in cultured human skin cells.

HAS1 HAS3

7.53e-05412429457904
Pubmed

Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk.

TYRO3 LTK

7.53e-05412428661736
Pubmed

β1, β2, and β3 adrenoceptors and Na+/H+ exchanger regulatory factor 1 expression in human bronchi and their modifications in cystic fibrosis.

ADRB1 ADRB3

7.53e-054124220203292
Pubmed

The control and importance of hyaluronan synthase expression in palatogenesis.

HAS1 HAS3

7.53e-054124223382716
GeneFamilyAlpha-1,2-glucosyltransferases

ALG10B ALG10

2.40e-052892448
GeneFamilyGlycosyltransferase family 2

HAS1 HAS3

3.55e-046892428
GeneFamilyAdrenoceptors

ADRB1 ADRB3

8.43e-049892169
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D9B TBC1D9

1.80e-03138921146
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

ARHGAP32 KLHL40 DUSP5 SLC30A3 BMP3 ADRB1 LTK TRBC2

1.49e-08159123818e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 REL NIBAN3 TXK B3GNT8 EBI3 ZC3H12D

2.44e-071541237ee03b386d28a524084eaf1c0091f7389daa34250
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 REL NIBAN3 TXK B3GNT8 EBI3 ZC3H12D

2.44e-0715412373fa6f77ad2c30ec24b9b904e2732ec5b419dff5b
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Dkk3_(Deep_layer_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 SLC30A3 BMP3 LTK TRBC2 MED12

7.74e-0711412363352ce794a646e3e7f15a991dd8a847a3c705394
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 SLC30A3 BMP3 LTK TRBC2 MED12

7.74e-071141236158dc333b337d5e83183b2f010a8e030c7a57bc7
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Dkk3_(Deep_layer_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 SLC30A3 BMP3 LTK TRBC2 MED12

7.74e-071141236238f2541e0514df8d24d767f833980d770b920a4
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 SLC30A3 BMP3 LTK TRBC2 MED12

7.74e-071141236e63c0ebf843392c2926732bb8792eb6ee69bec15
ToppCellSevere-B_naive-9|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

AFF3 REL NIBAN3 TMEM78 KEL TRBC2

2.46e-061391236b9b049953958f15d773eb5cca6d5dc34f4829543
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 REL NIBAN3 B3GNT8 STXBP2 EBI3

5.55e-061601236cfd005e98944817458e8ef9e0c436d77f50c1ad1
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2C1 RNF183 STXBP2 P3H2 ZC3H12D UBA6

6.39e-06164123654f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ARHGAP32 AFF3 REL NIBAN3 CEMIP2 ITPR1

7.59e-061691236c3a6179a64589a370108fea809b157839347759c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ATG9B DNAH2 NFASC BEST4 CFAP46 DNAH11

1.02e-0517812363b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellILEUM-non-inflamed-(1)_T_(gd)|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RIN3 CEMIP2 TXK ADRB1 TRBC2 TRBC1

1.09e-05180123644c37644973c4fc555dc966f8cfe1f4f81fef300
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 AFF3 REL NIBAN3 ZC3H12D VARS1

1.12e-05181123614faef1dde781d501834379f2a6413e8d6a80b72
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RIN3 GPR25 TXK MED12L TRBC2 TRBC1

1.16e-0518212366bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCellsevere-B_naive|World / disease stage, cell group and cell class

DUSP5 AFF3 REL NIBAN3 ITPR1 BMP3

1.48e-0519012368dfe067d75573289299a5fba42b6c9b26e5fb430
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

DUSP5 AFF3 SEMA5A NIBAN3 P3H2 LTK

1.52e-05191123693adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCellnormal_Lung-Epithelial_cells-AT2|normal_Lung / Location, Cell class and cell subclass

MBIP B3GNT8 ARFGEF3 BMP3 P3H2 HAS3

1.62e-05193123680ad1bdc50ecb8a50362f718248441cae20904a6
ToppCellILEUM-inflamed-(6)_ILC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RIN3 AFF3 REL CEMIP2 TXK TRBC1

1.66e-0519412364d51d49366c34ff1241770b4acc0167a43b3155a
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Tregs|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ORC3 HTATIP2 EBI3 ZC3H12D TRBC2 TRBC1

1.66e-0519412360396457834bbfed8d0b9b2ddaaecd9f28e1d56ed
ToppCell3'_v3-Lung-Myeloid_Dendritic|Lung / Manually curated celltypes from each tissue

DUSP5 AFF3 NIBAN3 ADRB3 EBI3 P3H2

1.71e-051951236b748cb15846345363e8c2ee5936bb42bba3ba9a7
ToppCellmild-pDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DUSP5 AFF3 SEMA5A NIBAN3 MED12L LTK

1.81e-0519712360cb00daa6943f7a7fb34a8fdf51188646af65686
ToppCellBAL-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DUSP5 AFF3 REL ADRB3 EBI3 P3H2

1.81e-0519712366f83fc049f38f3de6bc5180ad4b51ceb4d5dcdb6
ToppCellBAL-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DUSP5 AFF3 REL ADRB3 EBI3 P3H2

1.81e-0519712366ac50c02899531a25885749d5305da788dfa9dbc
ToppCellmild-pDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DUSP5 AFF3 SEMA5A NIBAN3 MED12L LTK

1.81e-05197123615230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCellControl|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RIN3 AFF3 REL NIBAN3 EEF2 TRBC2

1.87e-05198123673694b6109c1f6878b6b5997e434bbc3cec1dc70
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP8B3 DUSP5 F9 B3GNT2 HELZ2 CFAP46

1.92e-0519912366dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCelldistal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MBIP B3GNT8 ARFGEF3 BMP3 P3H2 HAS3

1.97e-052001236a77087a393aad674d4aa457ca6c0077b0424053d
ToppCellCaecum-(1)_T_cell-(17)_gd_T|Caecum / shred on region, Cell_type, and subtype

RIN3 GPR25 TXK ADRB1 TRBC2 TRBC1

1.97e-0520012362aaa6b37e9f8d95de53f284a42a3ac14e6351b40
ToppCellCaecum-T_cell-gd_T|Caecum / Region, Cell class and subclass

RIN3 GPR25 TXK ADRB1 TRBC2 TRBC1

1.97e-052001236eaacd14b6d4a1c7d52deab110ed3a6c7d3dc1f8e
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Proliferative_Immature_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

F9 TYRO3 ADRB3 BOP1 CFAP46

3.67e-051351235ed0f94d3839eea3b60217c4352159ed481361f13
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

AFF3 REL NIBAN3 CEMIP2 ITPR1

5.69e-051481235dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCellControl-B_intermediate-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

RIN3 TBC1D9B IL25 TBC1D9 EBI3

5.69e-051481235662c057030effc9eb61216e81d3967e6983c244f
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIBAN3 TXK CHST13 TRBC2 TRBC1

7.09e-051551235efe69145910c5e049d0ed30699c26ef963e0a285
ToppCelldroplet-Fat-Scat-21m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF3 NIBAN3 LTK VARS1 DNAH11

8.48e-051611235e52735f955f0a53da5cbe5a2d77a00484e5109b3
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF3 NIBAN3 BST1 STEAP3 VARS1

8.73e-05162123559f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF3 REL NIBAN3 EBI3 VARS1

9.52e-051651235953c8242a81a39ade63ac8e5b34fe58575771746
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DPF1 AFF3 NIBAN3 ITPR1 MED12L

9.52e-0516512358b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TXK CHST13 TRBC2 TRBC1 VARS1

9.52e-051651235ec16a4979b3f203c9f66ed387a7a17bf3a1d3f86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DPF1 AFF3 NIBAN3 ITPR1 MED12L

9.52e-051651235243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

REL ST3GAL3 EBI3 ZC3H12D MED12L

9.52e-051651235c39f0479955c4e23921f7a450d3bc251a002200f
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL25 EVX1 DCAF12L2 F9

9.93e-058712348ca87e4a332ef6f035b13e80dcc0110f32172c9a
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL25 EVX1 DCAF12L2 F9

9.93e-058712344ec3a9489981ed69061c1ca363271edf6a3635d2
ToppCellfacs-Heart-LV-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 NIBAN3 STXBP2 ZC3H12D VARS1

1.01e-0416712354a669eafde3582a451614ad304769b47aa1d9578
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADCY10 RIN3 TXK TRBC2 TRBC1

1.04e-0416812352765d98f0b7f6861d662937535e051d41dba3500
ToppCell390C-Myeloid-Dendritic-pDC|390C / Donor, Lineage, Cell class and subclass (all cells)

DUSP5 AFF3 NIBAN3 MED12L LTK

1.04e-0416812355a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIN3 TXK ADRB1 TRBC2 TRBC1

1.04e-041681235b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 NIBAN3 STXBP2 ZC3H12D VARS1

1.06e-041691235ae85cef7ef8f761c19f4af2a23fe333641c38a92
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 NIBAN3 STXBP2 ZC3H12D VARS1

1.06e-041691235c01bc3f2f299109086ded83dc11e98559bf1940c
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AFF3 CALHM3 NIBAN3 B3GNT2 TRBC2

1.09e-0417012358d6419ffe7dc1a0483c174d8e4b29704895eb9cf
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FANCD2 NEU1 EBI3 ZC3H12D SIGLEC1

1.13e-04171123541932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

AFF3 REL NIBAN3 BMP3 ATAD2B

1.19e-041731235694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellILEUM-inflamed-(1)_T_(gd)|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RIN3 CEMIP2 TXK ADRB1 TRBC1

1.19e-04173123585c3e227c81c6ab70148639381389fba3ac5e088
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXK FANCD2 EBI3 ZC3H12D CTSG

1.22e-041741235723848d2f8ae9cf4f15d4b4a130f9a64dab443c7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RIN3 REL TXK TRBC2 TRBC1

1.25e-0417512352f43883d7c89f09b0579a390a7431f1f9b832582
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RIN3 REL TXK TRBC2 TRBC1

1.25e-041751235da92eb8af0c7c65fed4a1d960708240f35dd997d
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIN3 TXK ADRB1 TRBC2 TRBC1

1.29e-041761235dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCellHealthy_Control-Lymphoid-T-Treg|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ATG9B TGFB1I1 ZC3H12D TRBC2 TRBC1

1.29e-0417612357765a5b04ac117d525201f8eb08e1754e55942ff
ToppCellfacs-GAT-Fat-24m-Lymphocytic-B_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUSP5 REL NIBAN3 ZC3H12D VARS1

1.32e-041771235f4afe10522eed77318954210224496f09d372532
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TXK UBA6 TRBC2 TRBC1 MED12

1.32e-041771235f10f77130dbb2c0ad1b436ceb4fb1deac2b0267c
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZSWIM3 LCORL MED12L CCAR2 ZNF654

1.32e-0417712358abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell(1)_T_regulatory|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ORC3 EBI3 ZC3H12D TRBC2 TRBC1

1.32e-0417712355cda56b10df1ee8971ce8470d52062e01b703a4e
ToppCellHealthy_Control-Lymphoid-NK-NK|Healthy_Control / Condition, Lineage, Cell class and cell subclass

AFF3 TXK ADRB1 TRBC2 TRBC1

1.36e-04178123571e99f143009b2d29cb47b96393b58b514c8cfc6
ToppCellnormal_Lymph_Node-T/NK_cells-Exhausted_CD8+_T|normal_Lymph_Node / Location, Cell class and cell subclass

DUSP5 CEMIP2 ADRB1 B3GNT2 TRBC2

1.39e-0417912353dc929a10381b7d86650c6cd8f354892fe1d93e7
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR25 TXK STXBP2 TRBC2 TRBC1

1.43e-041801235ca7c316027e31559103b2cab1a2c0de993e42e95
ToppCellSevere-Lymphoid-B|Severe / Condition, Lineage, Cell class and cell subclass

GPR25 AFF3 EBI3 GTSF1L TRBC2

1.43e-04180123567ffaf5096f025c3c61fffe52f6c8a96f120fc6f
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR25 TXK STXBP2 TRBC2 TRBC1

1.43e-041801235eb26ba86fba26899e54c448afc25382ddc853013
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

AFF3 BTBD9 MBIP ARFGEF3 P3H2

1.43e-041801235198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellSevere-Lymphoid-B-|Severe / Condition, Lineage, Cell class and cell subclass

GPR25 AFF3 EBI3 GTSF1L TRBC2

1.43e-041801235fd3eb751704b14ff1500e4bd041441644d233e9c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TXK ZC3H12D LTK TRBC2 TRBC1

1.43e-041801235d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIN3 TXK ADRB1 TRBC2 TRBC1

1.47e-041811235ee1c5af8ed75dd8a0ed3152ba5b9a42d2a8c2ae4
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL NFASC SEMA5A EPX ZNF579

1.47e-0418112354e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL NFASC SEMA5A EPX ZNF579

1.47e-041811235ad30c01290fb98adbd0caed301a584761212c977
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

AFF3 SEMA5A NIBAN3 P3H2 LTK

1.47e-0418112353d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPF1 TMPRSS9 EPX MED12L KEL

1.47e-041811235070ae3f3fe0e177fabcf34e64a0f158b01354837
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL NFASC SEMA5A EPX ZNF579

1.47e-0418112353a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL25 AFF3 NIBAN3 TBC1D9 EBI3

1.54e-04183123582fe14fc7039415de41bdfd615a1380bed99f560
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NIBAN3 TXK TRBC2 TRBC1 VARS1

1.54e-041831235b9e14199abc13a4873a77d23be1a37b0d4599b0f
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR25 AFF3 TXK TRBC2 TRBC1

1.54e-0418312354a1e5bf58d2acd9dbceeef538b6851c1e5e91059
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DUSP5 TBC1D9 NEU1 BST1 SIGLEC1

1.58e-0418412358e5fc2bdd3071e782aa8c56b8a39f8ea8f03f623
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF3 REL NIBAN3 EBI3 MED12L

1.63e-04185123505e6eb78ead81268c1656e7ffe34f9cb7329b908
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

DUSP5 SEMA5A NIBAN3 P3H2 MED12L

1.63e-0418512353091870a5bf8ecb963e560b47c8502bae367416c
ToppCellcontrol-Myeloid-pDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DUSP5 SEMA5A NIBAN3 P3H2 LTK

1.67e-041861235fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GPR25 CEMIP2 TXK TRBC2 TRBC1

1.67e-041861235165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF3 NIBAN3 B3GNT8 ZC3H12D VARS1

1.67e-041861235a8fcb440d88770f95678c5d28413fc4d847f42a8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMPRSS9 ARHGAP32 KCND1 BST1 SIGLEC1

1.67e-041861235f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

DUSP5 SEMA5A NIBAN3 P3H2 LTK

1.67e-041861235916f2aeea4989ba7a29e071e348a51010f010223
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

DUSP5 SEMA5A NIBAN3 P3H2 LTK

1.67e-041861235fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMPRSS9 ARHGAP32 KCND1 BST1 SIGLEC1

1.67e-0418612358694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF3 NIBAN3 B3GNT8 ZC3H12D VARS1

1.67e-0418612356b2d15e2756d4d4d68ad600e4a6c074edc3488f2
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF3 NIBAN3 TBC1D9 CEMIP2 EBI3

1.67e-041861235d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMPRSS9 CHST13 BST1 MED12L KEL

1.67e-041861235722da08cd978249a19855fd3ec8ddda780c99d83
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

DUSP5 SEMA5A NIBAN3 P3H2 LTK

1.67e-04186123545f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell10x5'v1-week_12-13-Lymphocytic_T-T_NK-NK_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GPR25 TXK HAS3 TRBC2 TRBC1

1.67e-041861235b099cb0902e9afb11218d70407d3cab212343c6d
ToppCell390C-Myeloid-Dendritic-cDC_activated|390C / Donor, Lineage, Cell class and subclass (all cells)

DUSP5 VPS8 TBC1D9 ADRB3 EBI3

1.71e-04187123560c2576f31a60f819deb9ec500d1f714b469df4e
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

AFF3 TXK HAS1 TRBC2 TRBC1

1.71e-041871235f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ATG9B ORC3 TXK TRBC2 TRBC1

1.75e-041881235b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellPBMC-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

AFF3 SEMA5A NIBAN3 P3H2 LTK

1.75e-04188123589411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

AFF3 REL NIBAN3 CEMIP2 ITPR1

1.75e-041881235ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AFF3 REL NIBAN3 CEMIP2 ITPR1

1.75e-041881235d8decd9b5967873ca8320c2f9f07365f163c777f
DrugAC1L98DX

TRPC1 ITPR1 DFFB EEF2 BST1

1.70e-06381215CID000439957
Drugoxprenolol

MAN2C1 ADRB1 ADRB3

1.20e-0591213CID000004631
Drugcimaterol

ADRB1 ADRB3 KEL CTSG

1.63e-05291214CID000002755
Drug8-amino-cADPR

ITPR1 DFFB BST1

2.34e-05111213CID003081323
DrugAC1O3SYO

TYRO3 FASTK

2.80e-0521212CID005489529
DrugBupranolol

ADRB1 ADRB3

2.80e-0521212ctd:D002046
Drugbefunolol

ADRB1 ADRB3 PROK1

4.03e-05131213CID000002309
Drugamosulalol

ADRB1 ADRB3 KEL

6.36e-05151213CID000002169
DrugHV723

ADRB1 ADRB3 PROK1

6.36e-05151213CID003081094
Drugpyridine hemochrome

EPX PNKD F9 FANCD2

7.27e-05421214CID000188327
Drugpoly(methylmethacrylate

ARHGAP32 MAN2C1 MMAB

7.80e-05161213CID000522750
Drugarbutamine

ADRB1 ADRB3

8.37e-0531212ctd:C076559
DrugN-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide

ADRB1 ADRB3

8.37e-0531212ctd:C568515
Drug3-iodopindolol

ADRB1 ADRB3

8.37e-0531212CID000123825
Drugp-azidobenzylcarazolol

ADRB1 ADRB3

8.37e-0531212CID000133262
DrugFenoterol

ADRB1 ADRB3

8.37e-0531212DB01288
DrugLCB 2183

ADRB1 ADRB3

8.37e-0531212CID000133046
DrugU-43,465F

ADRB1 ADRB3

8.37e-0531212CID000134388
DrugArbutamine

ADRB1 ADRB3

8.37e-0531212DB01102
Drugbroxaterol

ADRB1 ADRB3

8.37e-0531212ctd:C045916
DrugpBABC

ADRB1 ADRB3

8.37e-0531212CID000126676
DrugEXP063

ADRB1 ADRB3

8.37e-0531212CID003037493
DrugICYP-azide-2

ADRB1 ADRB3

8.37e-0531212CID003036190
DrugBAM-CYP

ADRB1 ADRB3

8.37e-0531212CID000125252
Drugbutofilolol

ADRB1 ADRB3

8.37e-0531212CID000068838
Drugsoquinolol

ADRB1 ADRB3

8.37e-0531212CID000068811
DrugCS 476

ADRB1 ADRB3

8.37e-0531212CID000100459
Drugexaprolol

ADRB1 ADRB3

8.37e-0531212CID000065484
DrugAHR-9377

ADRB1 ADRB3

8.37e-0531212CID000054961
Drugdicyclopropyl ketoxime

ADRB1 ADRB3

8.37e-0531212CID000015072
Drug2-hydroxysebacate

EEF2 MED12

8.37e-0531212CID000128458
DrugOberadilol

ADRB1 ADRB3

8.37e-0531212CID003047798
DrugCGP-12177-NBD

ADRB1 ADRB3

8.37e-0531212CID003081105
DrugBupranolol

ADRB1 ADRB3

8.37e-0531212DB08808
Drugp-azidoclonidine

ADRB1 ADRB3

8.37e-0531212CID003035819
DrugICYP-azide-1

ADRB1 ADRB3

8.37e-0531212CID000133837
DrugAC1L4W2Z

ADRB1 ADRB3

8.37e-0531212CID000193350
DrugH 216/44

ADRB1 ADRB3

8.37e-0531212CID000130141
DrugAC1L1TT8

ADRB1 ADRB3

8.37e-0531212CID000060729
DrugADATN

ADRB1 ADRB3

8.37e-0531212CID000133861
DrugPractolol [6673-35-4]; Up 200; 15uM; MCF7; HT_HG-U133A

TRPC1 EPX SLC30A3 ITPR1 BST1 RECQL5 GREB1

8.69e-0519612173204_UP
DrugAntimycin A [1397-94-0]; Down 200; 7.2uM; MCF7; HT_HG-U133A

MBIP TGFB1I1 DFFB TRMT2A ATAD2B RECQL5 MMP14

9.55e-0519912175472_DN
Drugtalinolol

TBC1D9 ADRB1 ADRB3

1.13e-04181213CID000068770
Drugv315

ADRB1 ADRB3

1.67e-0441212CID000053925
DrugNHNPNBE

ADRB1 ADRB3

1.67e-0441212CID006453817
Drugeclanamine

ADRB1 ADRB3

1.67e-0441212CID000051228
DrugTobanum

ADRB1 ADRB3

1.67e-0441212CID000065814
Drugflestolol

ADRB1 ADRB3

1.67e-0441212CID000055884
DrugDAPN

ADRB1 ADRB3

1.67e-0441212CID000125184
DrugSOM-1122

ADRB1 ADRB3

1.67e-0441212CID000068918
Drugtienoxolol

ADRB1 ADRB3

1.67e-0441212CID000065678
DrugAlp-NBD

ADRB1 ADRB3

1.67e-0441212CID000126953
Drugi 583

ADRB1 ADRB3

1.67e-0441212CID000072881
Drugcyanopindolol

ADRB1 ADRB3

1.67e-0441212ctd:C047975
Drugacebutolol azide

ADRB1 ADRB3

1.67e-0441212CID000133410
DrugCGP 20712A

ADRB1 ADRB3

1.67e-0441212ctd:C049763
Drugiodoazidobenzylpindolol

ADRB1 ADRB3

1.67e-0441212CID000132676
DiseaseLong Qt Syndrome 2

ALG10B ALG10

5.07e-0531222C3150943
Diseasenephrotic syndrome type 20 (implicated_via_orthology)

TBC1D9B TBC1D9

1.01e-0441222DOID:0070357 (implicated_via_orthology)
DiseaseOvarian cyst

IFNL4 GREB1

1.68e-0451222HP_0000138
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10B ALG10

2.52e-0461222DOID:0050563 (implicated_via_orthology)
Diseasepantothenate measurement

SLC30A3 DFFB

4.67e-0481222EFO_0021034
Diseasen-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 measurement

B3GNT8 B3GNT2

5.99e-0491222EFO_0801817
Diseasebody height at birth

LCORL ADRB1 ATAD2B

6.09e-04401223EFO_0006784
Diseasereticulocyte measurement

LCORL PIEZO1 AFF3 RFC1 PNKD PRPF8 ADRB1 ATAD2B KEL SIGLEC1 MMAB MED12

1.42e-03105312212EFO_0010700
DiseaseBirth Weight

LCORL ADRB1

1.49e-03141222C0005612
Diseaseclonal hematopoiesis mutation measurement

ITPR1 STXBP2 HERC2

1.55e-03551223EFO_0020949
Diseaselysophosphatidylcholine 14:0 measurement

SLC30A3 DFFB

1.72e-03151222EFO_0010356
DiseaseAstigmatism

AFF3 BMP3 GTSF1L HERC2

2.06e-031291224HP_0000483
DiseaseParkinson disease

TMPRSS9 LCORL SEMA5A BST1 MED12L LTK

2.23e-033211226MONDO_0005180
Diseasenon-alcoholic fatty liver disease (is_implicated_in)

IFNL4 ADRB3

2.48e-03181222DOID:0080208 (is_implicated_in)
Diseasesquamous cell carcinoma

RXFP3 HERC2 DNAH11

2.72e-03671223EFO_0000707
Diseaseskin sensitivity to sun

RXFP3 HERC2

2.77e-03191222EFO_0004795
Diseasecataract

LCORL BMP3 HERC2 MMAB

2.84e-031411224MONDO_0005129
DiseaseArthrogryposis

ERCC6 VPS8

3.38e-03211222C0003886

Protein segments in the cluster

PeptideGeneStartEntry
ARYCNRSADLIPLSF

BEST4

66

Q8NFU0
QERFERCLDLYLCPR

BOP1

361

Q14137
PICDFLELQRRYRSL

CCAR2

236

Q8N163
SLCVYEPDRNALRRK

AFF3

16

P51826
IYCRSPDFRKAFQRL

ADRB1

376

P08588
IFLGRCAEYRALLSP

BST1

46

Q10588
EPRNCARRYLKVDFA

BMP3

366

P12645
EPVSRCQRLSELYLR

CFAP410

56

O43822
LRPCFDQTVFLQRRY

CALHM3

201

Q86XJ0
YNARLCAERSLRLPF

DPF1

26

Q92782
NYVSRPRRCELAAAL

EVX1

206

P49640
NYVSRPRRCELAAAL

EVX2

211

Q03828
CANPLIYLLLDRSFR

GPR25

301

O00155
ALCNPHIQADRLRYR

AP4B1

16

Q9Y6B7
RLRLCTTLYQAPERA

CFAP46

471

Q8IYW2
ARECYRPVAARASLL

DNAH11

3701

Q96DT5
CLLFSAFSRALREPY

ALG10B

21

Q5I7T1
SRRDFLYARRLSLLC

ATP8B3

856

O60423
RFQLPERGSRLCLYE

DFFB

36

O76075
RLSRCLLLNSRYPQL

ADCY10

1341

Q96PN6
YCRSPDFRSAFRRLL

ADRB3

346

P13945
YLRDPIDLRACRVFK

ECD

236

O95905
ACVLRDTINPYLLRR

ERCC6

731

Q03468
IRFDQLHREYCLSPR

HJURP

436

Q8NCD3
FFRRHGTPRRLLYCQ

MMP14

561

P50281
GTPRRLLYCQRSLLD

MMP14

566

P50281
AASLCLPRYSFRRLD

P2RX4

266

Q99571
TSQREYLRLLDALCP

NIBAN3

156

Q86XR2
APAARAFLDAVRLYR

NIBAN3

236

Q86XR2
LEAALSCPRFLRYPR

FASTK

206

Q14296
YLLRLFAAPSRCRFL

KCND1

246

Q9NSA2
SRRLAYFCARRLSLL

MED12L

291

Q86YW9
YFCARRLSLLLSDSP

MED12L

296

Q86YW9
RYSVFRPGVLLCDRQ

HTATIP2

161

Q9BUP3
GESLPRSLRYCDLRL

GREB1

1036

Q4ZG55
DENLPYDLRASFCRL

ITPR1

771

Q14643
RIPLSRFQYHLASCR

GTSF1L

16

Q9H1H1
ERLRFLFNELRPAVC

HERC2

1511

O95714
LCTEAALIALRRRYP

ATAD2B

616

Q9ULI0
RAQAALYAPALRLRD

LINC02693

71

A8MQB3
YGPRLRRDLSLFEDC

LCORL

61

Q8N3X6
SRLLSIRLPYCRENV

DCAF12L2

296

Q5VW00
PLFLIYCRALNSRGE

DSG4

121

Q86SJ6
LRPSFASILERLQYC

LTK

766

P29376
PLLACLFENQFRRAR

EPX

631

P11678
YLRVPLVDRATCLRS

F9

371

P00740
RLAYFCTRRLALQLD

MED12

296

Q93074
LAACSPYFRARFLAE

KLHL40

51

Q2TBA0
FESVRCRLLPRAFLE

KLHL40

221

Q2TBA0
ELPLFRSLLGRARCY

P3H2

106

Q8IVL5
RDLLRYAAQLPALFR

PELP1

156

Q8IZL8
CIYDRRFSQLSELPR

ARHGAP32

186

A7KAX9
LPNLLCSRFPDGRYR

PROK1

81

P58294
LARYCLRAPFGRNLI

FBXO17

96

Q96EF6
RVILYNRTRLDCPFF

NFASC

441

O94856
DLCLPALDYLRRCSQ

ARFGEF3

1386

Q5TH69
AALTLPRVQCRASRY

EBI3

26

Q14213
REYLCLDNSARFRPH

CEMIP2

746

Q9UHN6
ARLARAYRPAAAFLR

ATG9B

501

Q674R7
LRQCLASARALLYPR

HAS1

111

Q92839
AAAPRRCLLSHYRSL

IFNL4

21

K9M1U5
VSPLYFTDCNLRGRL

MAN2C1

21

Q9NTJ4
CRPNLSREVLYEIFR

MBIP

21

Q9NS73
CAYIRSLAPSLLDRN

TMEM167A

21

Q8TBQ9
HCSLVSLRFPRFYLR

LCE7A

56

P0DV60
QCLRIFGSYDPRRQI

CTSG

171

P08311
RDLNRLPQDLYHARC

IL25

96

Q9H293
EDPDYLRKCLRSAQR

HAS3

96

O00219
RRCLYASVLTAQPRL

EEF2

726

P13639
LRRHRLRSDCFYEQP

HELZ2

1496

Q9BYK8
YPKDLRRFLLSAACR

B3GNT8

111

Q7Z7M8
RFPAHRVILAARCQY

BTBD9

46

Q96Q07
DLAREAYRPCAQRAS

DNAH2

3601

Q9P225
LACFRNAIRVNPRHY

CDC27

621

P30260
LDCRPYLAFAASNVR

DUSP5

26

Q16690
APYFRLLRLCVERQH

FANCD2

731

Q9BXW9
CFGAARLLYPRFQSR

MMAB

21

Q96EY8
AFYCVSRDLLPFTLR

RIN3

141

Q8TB24
NQCENIRRLPSFRRY

ORC3

361

Q9UBD5
CYLLLVRFIADRRAA

RXFP3

286

Q9NSD7
LRADYNLTRIRPDCF

VARS1

1121

P26640
RAKNLRRLLYVSCNP

TRMT2A

526

Q8IZ69
ERSYNPFLRTHCLAL

PNKD

336

Q8N490
LRECFRNPQFRIFAY

RNF183

151

Q96D59
RSLVHYCFDLRFQRP

RFC1

761

P35251
IVLRSYDACDTLRPR

NEU1

291

Q99519
YRLTPALDSLRCRRC

ST3GAL3

146

Q11203
AFDQLCRLYRGSSRL

VPS8

1366

Q8N3P4
PRARDFYRQFCVKLA

MROH2B

1481

Q7Z745
EQRFRYTCKARLADP

SEMA5A

726

Q13591
KNECYRATFRLPRDE

TBC1D9B

286

Q66K14
TPEAKAFIRRCLAYR

TLK2

711

Q86UE8
RCLYGALSDPIRRAL

ABTB1

71

Q969K4
NLPDRFKDFLLYLRC

B3GNT2

111

Q9NY97
CLLFSAFSRALREPY

ALG10

21

Q5BKT4
SPAEINRRLRAYLAF

CHST13

156

Q8NET6
RFFCRRVESPALLAS

RECQL5

766

O94762
ARYLQLDAARLVRCN

RNF31

46

Q96EP0
AAHPIRLFCRYIDRI

PRPF8

1081

Q6P2Q9
RFRLDIYRCLASPAL

TRPC1

211

P48995
IQCLRRYRDTKRAFP

XPR1

461

Q9UBH6
FLPRGDRYDALRACI

UBA6

436

A0AVT1
YVDSRCLANLRPLLD

UBA6

576

A0AVT1
AARAFAQRYLADLLP

RSPH3

396

Q86UC2
DFTPNAYLARRRFQC

ZNF815P

86

A8K554
ALRSLYRARPSLRCP

NDUFAF3

6

Q9BU61
FCLPLRRAHRYDLVN

STEAP3

321

Q658P3
YARPRFLRLQESLAT

SLC27A3

616

Q5K4L6
PALNDSRYCLSSRLR

TRBC1

66

P01850
LYCPFRAEERTRQLE

STXBP2

156

Q15833
AALRRVLTAYAFRNP

TBC1D9

581

Q6ZT07
FELRARYLIACERIP

ZNF654

196

Q8IZM8
AVRLLSEQTCRRFYP

TMPRSS9

971

Q7Z410
NYNARLCAERSVRLP

DPF2

26

Q92785
RLRLADCLVPYSRAL

TMEM88

116

Q6PEY1
YDNRAPNTAELRICR

REL

176

Q04864
LLPVARTDAALYACR

SIGLEC1

761

Q9BZZ2
TPERLHARRQLYAAC

SLC30A3

66

Q99726
DARARARIALYSVFP

ZC3H12D

476

A2A288
YDFLPREPCNLALRR

TXK

91

P42681
CPAYLLLRYNERLDR

ZSWIM3

76

Q96MP5
PALNDSRYCLSSRLR

TRBC2

66

A0A5B9
RPYCRRDFLQLFAPR

TGFB1I1

331

O43294
CLSLAQGTYRPLRRF

PIEZO1

1931

Q92508
PDCGLAFRLASYLRQ

ZNF579

301

Q8NAF0
CPRRFSRAYSLLRHQ

ZNF579

446

Q8NAF0
NSYQIRREFLLPACL

TMEM78

41

Q5T7P6
RDLVPATNYSLRVRC

TYRO3

286

Q06418
NSAADPDYCRRILVR

VAX1

66

Q5SQQ9
FARYFRCARGALLNP

KEL

711

P23276