Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	Notch binding	DLL1 MEGF10 JAG1	4.97e-06	27	25	3	GO:0005112
GeneOntologyMolecularFunction	receptor ligand activity	HGF GRN DLL1 SEMA7A SEMA5B JAG1	4.67e-05	547	25	6	GO:0048018
GeneOntologyMolecularFunction	signaling receptor activator activity	HGF GRN DLL1 SEMA7A SEMA5B JAG1	5.01e-05	554	25	6	GO:0030546
GeneOntologyMolecularFunction	signaling receptor regulator activity	HGF GRN DLL1 SEMA7A SEMA5B JAG1	9.03e-05	616	25	6	GO:0030545
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNB2 PLXNB3	9.86e-05	12	25	2	GO:0017154
GeneOntologyMolecularFunction	calcium ion binding	PLA2G5 DLL1 MEGF8 VWA2 JAG1 PROC	2.62e-04	749	25	6	GO:0005509
GeneOntologyMolecularFunction	semaphorin receptor binding	SEMA7A SEMA5B	3.75e-04	23	25	2	GO:0030215
GeneOntologyMolecularFunction	chemorepellent activity	SEMA7A SEMA5B	5.98e-04	29	25	2	GO:0045499
GeneOntologyMolecularFunction	molecular function activator activity	HGF GRN DLL1 SEMA7A SEMA5B ALS2CL JAG1	6.04e-04	1233	25	7	GO:0140677
GeneOntologyMolecularFunction	growth factor activity	HGF GRN JAG1	1.28e-03	173	25	3	GO:0008083
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA5 EMILIN3 MUC4	1.62e-03	188	25	3	GO:0005201
GeneOntologyBiologicalProcess	regulation of cell development	TLE6 GRN TNFRSF1B DLL1 MEGF8 SEMA7A DCT PLXNB2 PLXNB3 JAG1 PROC	2.01e-08	1095	25	11	GO:0060284
GeneOntologyBiologicalProcess	regulation of nervous system development	TLE6 HGF TNFRSF1B DLL1 MEGF8 SEMA7A DCT PLXNB2 PLXNB3	2.69e-08	625	25	9	GO:0051960
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	TLE6 HGF PLA2G5 TNFRSF1B MEGF8 SEMA7A DCT PLXNB2 PLXNB3 JAG1 PROC	3.08e-08	1141	25	11	GO:0045597
GeneOntologyBiologicalProcess	regulation of neurogenesis	TLE6 TNFRSF1B DLL1 MEGF8 SEMA7A DCT PLXNB2 PLXNB3	1.06e-07	515	25	8	GO:0050767
GeneOntologyBiologicalProcess	regulation of locomotion	LAMA5 HGF GRN PLD1 MEGF8 SEMA7A SEMA5B PLXNB2 ANO6 PLXNB3 JAG1	1.44e-07	1327	25	11	GO:0040012
GeneOntologyBiologicalProcess	positive regulation of neurogenesis	TLE6 TNFRSF1B MEGF8 SEMA7A DCT PLXNB2 PLXNB3	1.52e-07	354	25	7	GO:0050769
GeneOntologyBiologicalProcess	positive regulation of cell development	TLE6 TNFRSF1B MEGF8 SEMA7A DCT PLXNB2 PLXNB3 PROC	4.07e-07	614	25	8	GO:0010720
GeneOntologyBiologicalProcess	semaphorin-plexin signaling pathway	SEMA7A SEMA5B PLXNB2 PLXNB3	4.37e-07	52	25	4	GO:0071526
GeneOntologyBiologicalProcess	positive regulation of nervous system development	TLE6 TNFRSF1B MEGF8 SEMA7A DCT PLXNB2 PLXNB3	4.68e-07	418	25	7	GO:0051962
GeneOntologyBiologicalProcess	regulation of cell migration	LAMA5 HGF GRN PLD1 SEMA7A SEMA5B PLXNB2 ANO6 PLXNB3 JAG1	6.81e-07	1211	25	10	GO:0030334
GeneOntologyBiologicalProcess	regulation of cell motility	LAMA5 HGF GRN PLD1 SEMA7A SEMA5B PLXNB2 ANO6 PLXNB3 JAG1	1.13e-06	1280	25	10	GO:2000145
GeneOntologyBiologicalProcess	chemotaxis	HGF PLD1 MEGF8 SEMA7A SEMA5B ANO6 PLXNB3	1.94e-06	517	25	7	GO:0006935
GeneOntologyBiologicalProcess	taxis	HGF PLD1 MEGF8 SEMA7A SEMA5B ANO6 PLXNB3	1.99e-06	519	25	7	GO:0042330
GeneOntologyBiologicalProcess	neural crest cell development	LAMA5 SEMA7A SEMA5B JAG1	3.82e-06	89	25	4	GO:0014032
GeneOntologyBiologicalProcess	regulation of embryonic development	LAMA5 TLE6 DLL1 JAG1	5.85e-06	99	25	4	GO:0045995
GeneOntologyBiologicalProcess	stem cell development	LAMA5 SEMA7A SEMA5B JAG1	6.33e-06	101	25	4	GO:0048864
GeneOntologyBiologicalProcess	neural crest cell differentiation	LAMA5 SEMA7A SEMA5B JAG1	7.11e-06	104	25	4	GO:0014033
GeneOntologyBiologicalProcess	axon development	LAMA5 GRN MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	8.07e-06	642	25	7	GO:0061564
GeneOntologyBiologicalProcess	negative regulation of inflammatory response	HGF PLA2G5 GRN TNFRSF1B PROC	8.81e-06	239	25	5	GO:0050728
GeneOntologyBiologicalProcess	regulation of cell adhesion	LAMA5 PLA2G5 DLL1 PLXNB2 MUC4 MEGF10 PLXNB3 JAG1	8.82e-06	927	25	8	GO:0030155
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	MEGF8 SEMA7A PLXNB2 PLXNB3	1.02e-05	114	25	4	GO:0050772
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	HGF PLA2G5 GRN DLL1 MEGF8 SEMA7A PLXNB2 ANO6 PLXNB3	1.85e-05	1366	25	9	GO:0051130
GeneOntologyBiologicalProcess	positive regulation of locomotion	HGF GRN PLD1 MEGF8 SEMA7A SEMA5B ANO6	2.07e-05	742	25	7	GO:0040017
GeneOntologyBiologicalProcess	inhibition of neuroepithelial cell differentiation	DLL1 JAG1	2.11e-05	6	25	2	GO:0002085
GeneOntologyBiologicalProcess	positive regulation of cell projection organization	HGF GRN MEGF8 SEMA7A PLXNB2 PLXNB3	2.20e-05	494	25	6	GO:0031346
GeneOntologyBiologicalProcess	mesenchymal cell differentiation	LAMA5 HGF SEMA7A SEMA5B JAG1	2.47e-05	296	25	5	GO:0048762
GeneOntologyBiologicalProcess	regulation of inflammatory response	HGF PLA2G5 GRN TNFRSF1B SEMA7A PROC	2.78e-05	515	25	6	GO:0050727
GeneOntologyBiologicalProcess	regulation of anatomical structure morphogenesis	HGF GRN DLL1 MEGF8 SEMA7A PLXNB2 PLXNB3 JAG1	2.86e-05	1090	25	8	GO:0022603
GeneOntologyBiologicalProcess	axonogenesis	LAMA5 MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	4.72e-05	566	25	6	GO:0007409
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	HGF GRN PLD1 MEGF8 SEMA7A PLXNB2 PLXNB3	4.79e-05	846	25	7	GO:0120035
GeneOntologyBiologicalProcess	immune effector process	PLA2G5 GRN TNFRSF1B DLL1 SEMA7A MUC4 JAG1	5.28e-05	859	25	7	GO:0002252
GeneOntologyBiologicalProcess	regulation of cell projection organization	HGF GRN PLD1 MEGF8 SEMA7A PLXNB2 PLXNB3	5.43e-05	863	25	7	GO:0031344
GeneOntologyBiologicalProcess	neural crest cell migration	LAMA5 SEMA7A SEMA5B	5.67e-05	62	25	3	GO:0001755
GeneOntologyBiologicalProcess	negative regulation of defense response	HGF PLA2G5 GRN TNFRSF1B PROC	5.72e-05	353	25	5	GO:0031348
GeneOntologyBiologicalProcess	mesenchymal cell migration	LAMA5 SEMA7A SEMA5B	6.24e-05	64	25	3	GO:0090497
GeneOntologyBiologicalProcess	loop of Henle development	DLL1 JAG1	6.31e-05	10	25	2	GO:0072070
GeneOntologyBiologicalProcess	regulation of neuron projection development	HGF GRN MEGF8 SEMA7A PLXNB2 PLXNB3	7.28e-05	612	25	6	GO:0010975
GeneOntologyBiologicalProcess	mesenchyme development	LAMA5 HGF SEMA7A SEMA5B JAG1	7.33e-05	372	25	5	GO:0060485
GeneOntologyBiologicalProcess	negative regulation of cell adhesion	PLA2G5 PLXNB2 MUC4 PLXNB3 JAG1	7.61e-05	375	25	5	GO:0007162
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	LAMA5 HGF DLL1 MEGF8 PLXNB2 JAG1	7.76e-05	619	25	6	GO:0002009
GeneOntologyBiologicalProcess	regulation of axonogenesis	MEGF8 SEMA7A PLXNB2 PLXNB3	7.90e-05	192	25	4	GO:0050770
GeneOntologyBiologicalProcess	neuron projection development	LAMA5 HGF GRN MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	9.24e-05	1285	25	8	GO:0031175
GeneOntologyBiologicalProcess	regulation of response to external stimulus	HGF PLA2G5 GRN TNFRSF1B MEGF8 SEMA7A ANO6 PROC	1.09e-04	1316	25	8	GO:0032101
GeneOntologyBiologicalProcess	positive regulation of cell migration	HGF GRN PLD1 SEMA7A SEMA5B ANO6	1.42e-04	691	25	6	GO:0030335
GeneOntologyBiologicalProcess	regulation of timing of cell differentiation	DLL1 JAG1	1.47e-04	15	25	2	GO:0048505
GeneOntologyBiologicalProcess	inflammatory response	HGF PLA2G5 GRN TNFRSF1B SEMA7A ANO6 PROC	1.78e-04	1043	25	7	GO:0006954
GeneOntologyBiologicalProcess	positive regulation of cell motility	HGF GRN PLD1 SEMA7A SEMA5B ANO6	1.85e-04	725	25	6	GO:2000147
GeneOntologyBiologicalProcess	regulation of development, heterochronic	DLL1 JAG1	1.90e-04	17	25	2	GO:0040034
GeneOntologyBiologicalProcess	positive regulation of neuron projection regeneration	HGF GRN	2.13e-04	18	25	2	GO:0070572
GeneOntologyBiologicalProcess	positive regulation of neuron projection development	HGF GRN PLXNB2 PLXNB3	2.15e-04	249	25	4	GO:0010976
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	LAMA5 MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	2.19e-04	748	25	6	GO:0048667
GeneOntologyBiologicalProcess	tissue morphogenesis	LAMA5 HGF DLL1 MEGF8 PLXNB2 JAG1	2.22e-04	750	25	6	GO:0048729
GeneOntologyBiologicalProcess	neuron development	LAMA5 HGF GRN MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	2.28e-04	1463	25	8	GO:0048666
GeneOntologyBiologicalProcess	negative regulation of neuroinflammatory response	GRN TNFRSF1B	2.64e-04	20	25	2	GO:0150079
GeneOntologyBiologicalProcess	regulation of immune effector process	PLA2G5 GRN TNFRSF1B SEMA7A MUC4	2.84e-04	497	25	5	GO:0002697
GeneOntologyBiologicalProcess	tube morphogenesis	LAMA5 HGF GRN DLL1 MEGF8 PLXNB2 JAG1	2.84e-04	1125	25	7	GO:0035239
GeneOntologyBiologicalProcess	nephron tubule development	LAMA5 DLL1 JAG1	3.12e-04	110	25	3	GO:0072080
GeneOntologyBiologicalProcess	negative regulation of response to external stimulus	HGF PLA2G5 GRN TNFRSF1B PROC	3.17e-04	509	25	5	GO:0032102
GeneOntologyBiologicalProcess	neuron projection morphogenesis	LAMA5 MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	3.18e-04	802	25	6	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	LAMA5 MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	3.56e-04	819	25	6	GO:0120039
GeneOntologyBiologicalProcess	axon guidance	LAMA5 MEGF8 SEMA7A SEMA5B	3.59e-04	285	25	4	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	LAMA5 MEGF8 SEMA7A SEMA5B	3.64e-04	286	25	4	GO:0097485
GeneOntologyBiologicalProcess	renal tubule development	LAMA5 DLL1 JAG1	3.64e-04	116	25	3	GO:0061326
GeneOntologyBiologicalProcess	cell projection morphogenesis	LAMA5 MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	3.73e-04	826	25	6	GO:0048858
GeneOntologyBiologicalProcess	pulmonary valve development	TNFRSF1B JAG1	3.83e-04	24	25	2	GO:0003177
GeneOntologyBiologicalProcess	cell morphogenesis	LAMA5 HGF MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	4.09e-04	1194	25	7	GO:0000902
GeneOntologyBiologicalProcess	stem cell differentiation	LAMA5 SEMA7A SEMA5B JAG1	4.70e-04	306	25	4	GO:0048863
GeneOntologyBiologicalProcess	nephron epithelium development	LAMA5 DLL1 JAG1	4.86e-04	128	25	3	GO:0072009
GeneOntologyBiologicalProcess	branching involved in salivary gland morphogenesis	LAMA5 HGF	5.23e-04	28	25	2	GO:0060445
GeneOntologyBiologicalProcess	positive regulation of myelination	HGF TNFRSF1B	5.61e-04	29	25	2	GO:0031643
GeneOntologyBiologicalProcess	skeletal muscle cell proliferation	HGF MEGF10	5.61e-04	29	25	2	GO:0014856
GeneOntologyBiologicalProcess	ameboidal-type cell migration	LAMA5 GRN MEGF8 SEMA7A SEMA5B	5.62e-04	577	25	5	GO:0001667
GeneOntologyBiologicalProcess	axon extension	MEGF8 SEMA7A SEMA5B	5.68e-04	135	25	3	GO:0048675
GeneOntologyBiologicalProcess	myoblast differentiation	DLL1 MEGF10 JAG1	5.80e-04	136	25	3	GO:0045445
GeneOntologyBiologicalProcess	epithelial cell proliferation	LAMA5 HGF GRN PLXNB3 JAG1	6.87e-04	603	25	5	GO:0050673
GeneOntologyBiologicalProcess	regulation of skeletal muscle tissue development	DLL1 MEGF10	7.28e-04	33	25	2	GO:0048641
GeneOntologyBiologicalProcess	endothelial cell differentiation	DLL1 JAG1 PROC	8.96e-04	158	25	3	GO:0045446
GeneOntologyBiologicalProcess	kidney epithelium development	LAMA5 DLL1 JAG1	9.63e-04	162	25	3	GO:0072073
GeneOntologyBiologicalProcess	salivary gland morphogenesis	LAMA5 HGF	9.65e-04	38	25	2	GO:0007435
GeneOntologyBiologicalProcess	T cell mediated immunity	TNFRSF1B MUC4 JAG1	9.81e-04	163	25	3	GO:0002456
GeneOntologyBiologicalProcess	regulation of defense response	HGF PLA2G5 GRN TNFRSF1B SEMA7A PROC	1.06e-03	1006	25	6	GO:0031347
GeneOntologyBiologicalProcess	tube development	LAMA5 HGF GRN DLL1 MEGF8 PLXNB2 JAG1	1.07e-03	1402	25	7	GO:0035295
GeneOntologyBiologicalProcess	phagocytosis, recognition	PLA2G5 MEGF10	1.18e-03	42	25	2	GO:0006910
GeneOntologyBiologicalProcess	nephron development	LAMA5 DLL1 JAG1	1.18e-03	174	25	3	GO:0072006
GeneOntologyBiologicalProcess	myoblast proliferation	HGF MEGF10	1.24e-03	43	25	2	GO:0051450
GeneOntologyBiologicalProcess	negative regulation of cell-matrix adhesion	MUC4 JAG1	1.24e-03	43	25	2	GO:0001953
GeneOntologyBiologicalProcess	salivary gland development	LAMA5 HGF	1.24e-03	43	25	2	GO:0007431
GeneOntologyBiologicalProcess	embryo development	LAMA5 TLE6 GRN DLL1 MEGF8 PLXNB2 JAG1	1.24e-03	1437	25	7	GO:0009790
GeneOntologyBiologicalProcess	endothelium development	DLL1 JAG1 PROC	1.35e-03	182	25	3	GO:0003158
GeneOntologyBiologicalProcess	cell-substrate adhesion	LAMA5 VWA2 MUC4 JAG1	1.40e-03	410	25	4	GO:0031589
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS15 LAMA5 EMILIN3 LAMB4 SEMA7A PLXNB2 VWA2 MUC4	1.69e-07	530	26	8	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	ADAMTS15 LAMA5 EMILIN3 LAMB4 SEMA7A PLXNB2 VWA2 MUC4	8.54e-07	656	26	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS15 LAMA5 EMILIN3 LAMB4 SEMA7A PLXNB2 VWA2 MUC4	8.73e-07	658	26	8	GO:0030312
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNB2 PLXNB3	1.15e-04	13	26	2	GO:0002116
GeneOntologyCellularComponent	specific granule membrane	PLD1 TNFRSF1B ANO6	1.93e-04	91	26	3	GO:0035579
GeneOntologyCellularComponent	cholinergic synapse	PLD1 ANO6	3.38e-04	22	26	2	GO:0098981
GeneOntologyCellularComponent	basement membrane	LAMA5 LAMB4 VWA2	4.57e-04	122	26	3	GO:0005604
GeneOntologyCellularComponent	secretory granule membrane	PLD1 TNFRSF1B PIGR ANO6	6.85e-04	329	26	4	GO:0030667
GeneOntologyCellularComponent	specific granule	PLD1 TNFRSF1B ANO6	1.01e-03	160	26	3	GO:0042581
GeneOntologyCellularComponent	secretory granule	HGF GRN PLD1 TNFRSF1B PIGR ANO6	1.28e-03	1014	26	6	GO:0030141
GeneOntologyCellularComponent	cell surface	ADAMTS15 PLA2G5 SEMA7A PLXNB2 ANO6 PLXNB3	2.04e-03	1111	26	6	GO:0009986
GeneOntologyCellularComponent	apical plasma membrane	PLD1 DLL1 MUC4 JAG1	2.90e-03	487	26	4	GO:0016324
GeneOntologyCellularComponent	secretory vesicle	HGF GRN PLD1 TNFRSF1B PIGR ANO6	3.64e-03	1246	26	6	GO:0099503
GeneOntologyCellularComponent	tertiary granule membrane	PLD1 ANO6	3.70e-03	73	26	2	GO:0070821
GeneOntologyCellularComponent	receptor complex	TNFRSF1B PIGR PLXNB2 PLXNB3	5.43e-03	581	26	4	GO:0043235
GeneOntologyCellularComponent	apical part of cell	PLD1 DLL1 MUC4 JAG1	5.80e-03	592	26	4	GO:0045177
GeneOntologyCellularComponent	Golgi lumen	MUC4 PROC	8.07e-03	109	26	2	GO:0005796
Domain	EGF_1	LAMA5 LAMB4 DLL1 MEGF8 VWA2 MUC4 MEGF10 JAG1 PROC	3.65e-11	255	26	9	PS00022
Domain	EGF-like_CS	LAMA5 LAMB4 DLL1 MEGF8 VWA2 MUC4 MEGF10 JAG1 PROC	4.50e-11	261	26	9	IPR013032
Domain	EGF_2	LAMA5 LAMB4 DLL1 MEGF8 VWA2 MUC4 MEGF10 JAG1 PROC	5.15e-11	265	26	9	PS01186
Domain	Plexin_repeat	MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	6.82e-10	32	26	5	IPR002165
Domain	PSI	MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	6.82e-10	32	26	5	PF01437
Domain	EGF	LAMA5 DLL1 MEGF8 VWA2 MUC4 MEGF10 JAG1 PROC	7.17e-10	235	26	8	SM00181
Domain	EGF-like_dom	LAMA5 DLL1 MEGF8 VWA2 MUC4 MEGF10 JAG1 PROC	1.13e-09	249	26	8	IPR000742
Domain	PSI	MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	3.64e-09	44	26	5	IPR016201
Domain	PSI	MEGF8 SEMA7A SEMA5B PLXNB2 PLXNB3	4.58e-09	46	26	5	SM00423
Domain	EGF_3	DLL1 MEGF8 VWA2 MUC4 MEGF10 JAG1 PROC	2.45e-08	235	26	7	PS50026
Domain	SEMA	SEMA7A SEMA5B PLXNB2 PLXNB3	9.05e-08	31	26	4	PS51004
Domain	Sema	SEMA7A SEMA5B PLXNB2 PLXNB3	9.05e-08	31	26	4	SM00630
Domain	Semap_dom	SEMA7A SEMA5B PLXNB2 PLXNB3	9.05e-08	31	26	4	IPR001627
Domain	Sema	SEMA7A SEMA5B PLXNB2 PLXNB3	9.05e-08	31	26	4	PF01403
Domain	Laminin_EGF	LAMA5 LAMB4 MEGF8 MEGF10	1.50e-07	35	26	4	PF00053
Domain	EGF_Lam	LAMA5 LAMB4 MEGF8 MEGF10	1.50e-07	35	26	4	SM00180
Domain	Laminin_EGF	LAMA5 LAMB4 MEGF8 MEGF10	2.11e-07	38	26	4	IPR002049
Domain	EGF_CA	DLL1 MEGF8 VWA2 JAG1 PROC	6.45e-07	122	26	5	SM00179
Domain	EGF-like_Ca-bd_dom	DLL1 MEGF8 VWA2 JAG1 PROC	7.00e-07	124	26	5	IPR001881
Domain	EGF	DLL1 VWA2 MUC4 JAG1 PROC	7.58e-07	126	26	5	PF00008
Domain	hEGF	DLL1 MEGF10 JAG1	7.67e-06	28	26	3	PF12661
Domain	EGF_Ca-bd_CS	DLL1 MEGF8 JAG1 PROC	9.36e-06	97	26	4	IPR018097
Domain	EGF_LAM_2	LAMA5 LAMB4 MEGF8	9.48e-06	30	26	3	PS50027
Domain	EGF_LAM_1	LAMA5 LAMB4 MEGF8	9.48e-06	30	26	3	PS01248
Domain	EGF_CA	DLL1 MEGF8 JAG1 PROC	1.02e-05	99	26	4	PS01187
Domain	ASX_HYDROXYL	DLL1 MEGF8 JAG1 PROC	1.06e-05	100	26	4	PS00010
Domain	DSL	DLL1 JAG1	1.12e-05	4	26	2	PF01414
Domain	DSL	DLL1 JAG1	1.12e-05	4	26	2	SM00051
Domain	EGF-type_Asp/Asn_hydroxyl_site	DLL1 MEGF8 JAG1 PROC	1.33e-05	106	26	4	IPR000152
Domain	DSL	DLL1 JAG1	1.86e-05	5	26	2	IPR001774
Domain	DSL	DLL1 JAG1	1.86e-05	5	26	2	PS51051
Domain	Notch_ligand_N	DLL1 JAG1	1.86e-05	5	26	2	IPR011651
Domain	MNNL	DLL1 JAG1	1.86e-05	5	26	2	PF07657
Domain	Growth_fac_rcpt_	LAMA5 DLL1 MEGF8 JAG1	6.07e-05	156	26	4	IPR009030
Domain	Plexin_cytopl	PLXNB2 PLXNB3	6.67e-05	9	26	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNB2 PLXNB3	6.67e-05	9	26	2	IPR013548
Domain	Plexin	PLXNB2 PLXNB3	6.67e-05	9	26	2	IPR031148
Domain	-	TLE6 SEMA7A SEMA5B PLXNB2 PLXNB3	8.45e-05	333	26	5	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	TLE6 SEMA7A SEMA5B PLXNB2 PLXNB3	8.69e-05	335	26	5	IPR015943
Domain	LAMININ_NTER	LAMA5 LAMB4	2.21e-04	16	26	2	PS51117
Domain	Laminin_N	LAMA5 LAMB4	2.21e-04	16	26	2	PF00055
Domain	EMI_domain	EMILIN3 MEGF10	2.21e-04	16	26	2	IPR011489
Domain	Laminin_N	LAMA5 LAMB4	2.21e-04	16	26	2	IPR008211
Domain	LamNT	LAMA5 LAMB4	2.21e-04	16	26	2	SM00136
Domain	EMI	EMILIN3 MEGF10	2.50e-04	17	26	2	PS51041
Domain	Semaphorin	SEMA7A SEMA5B	3.49e-04	20	26	2	IPR027231
Domain	IPT	PLXNB2 PLXNB3	6.40e-04	27	26	2	SM00429
Domain	TIG	PLXNB2 PLXNB3	8.45e-04	31	26	2	PF01833
Domain	IPT	PLXNB2 PLXNB3	9.01e-04	32	26	2	IPR002909
Domain	TNFR/NGFR_Cys_rich_reg	LAMA5 TNFRSF1B	9.58e-04	33	26	2	IPR001368
Domain	EGF_extracell	MEGF10 JAG1	3.14e-03	60	26	2	IPR013111
Domain	EGF_2	MEGF10 JAG1	3.14e-03	60	26	2	PF07974
Domain	TSP_1	ADAMTS15 SEMA5B	3.45e-03	63	26	2	PF00090
Domain	TSP1	ADAMTS15 SEMA5B	3.67e-03	65	26	2	SM00209
Domain	TSP1_rpt	ADAMTS15 SEMA5B	3.67e-03	65	26	2	IPR000884
Domain	TSP1	ADAMTS15 SEMA5B	3.67e-03	65	26	2	PS50092
Domain	EGF_CA	MEGF8 JAG1	6.34e-03	86	26	2	PF07645
Domain	Rho_GTPase_activation_prot	PLXNB2 PLXNB3	6.63e-03	88	26	2	IPR008936
Pathway	KEGG_AXON_GUIDANCE	SEMA7A SEMA5B PLXNB2 PLXNB3	4.31e-05	129	22	4	M5539
Pathway	REACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT	DLL1 JAG1	4.86e-05	7	22	2	M27199
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION	DLL1 JAG1	8.31e-05	9	22	2	M47866
Pathway	WP_CANCER_PATHWAYS	LAMA5 HGF LAMB4 PLD1 DLL1 JAG1	9.59e-05	507	22	6	M48302
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS15 SEMA5B MUC4	1.55e-04	68	22	3	M27303
Pathway	REACTOME_NEPHRON_DEVELOPMENT	DLL1 JAG1	1.79e-04	13	22	2	M48245
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	DLL1 JAG1	1.79e-04	13	22	2	M47423
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA7A PLXNB3	2.09e-04	14	22	2	MM15047
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	DLL1 JAG1	2.41e-04	15	22	2	M27202
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	DLL1 JAG1	2.75e-04	16	22	2	M47424
Pathway	WP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION	DLL1 JAG1	3.12e-04	17	22	2	M39389
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA7A PLXNB3	3.91e-04	19	22	2	M10959
Pathway	REACTOME_SIGNALING_BY_NOTCH3	DLL1 JAG1	3.91e-04	19	22	2	MM15594
Pathway	REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL1 JAG1	5.27e-04	22	22	2	M27210
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS15 SEMA5B MUC4	6.22e-04	109	22	3	MM15164
Pathway	REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING	LAMA5 HGF TNFRSF1B	6.56e-04	111	22	3	M27609
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS15 SEMA5B MUC4	6.56e-04	111	22	3	M27416
Pathway	REACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL1 JAG1	6.82e-04	25	22	2	M27879
Pathway	REACTOME_NEUTROPHIL_DEGRANULATION	GRN PLD1 TNFRSF1B PIGR ANO6	7.16e-04	478	22	5	M27620
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	DLL1 JAG1	7.97e-04	27	22	2	M39545
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA5 HGF	9.85e-04	30	22	2	M27772
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	LAMA5 TNFRSF1B	9.85e-04	30	22	2	M39641
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	LAMA5 TNFRSF1B	9.85e-04	30	22	2	MM15812
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	DLL1 JAG1	1.05e-03	31	22	2	M592
Pathway	KEGG_ETHER_LIPID_METABOLISM	PLA2G5 PLD1	1.19e-03	33	22	2	M2130
Pathway	REACTOME_SIGNALING_BY_NOTCH2	DLL1 JAG1	1.19e-03	33	22	2	M604
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS15 SEMA5B MUC4	1.37e-03	143	22	3	M27275
Pathway	KEGG_PATHWAYS_IN_CANCER	LAMA5 HGF LAMB4 PLD1	1.46e-03	325	22	4	M12868
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS15 SEMA5B	1.66e-03	39	22	2	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS15 SEMA5B	1.66e-03	39	22	2	MM15165
Pathway	REACTOME_SIGNALING_BY_NOTCH	DLL1 JAG1	1.66e-03	39	22	2	MM14604
Pathway	REACTOME_SYNTHESIS_OF_PA	PLA2G5 PLD1	1.66e-03	39	22	2	M653
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA5 HGF	1.84e-03	41	22	2	M27778
Pathway	WP_NOTCH_SIGNALING_WP268	DLL1 JAG1	2.21e-03	45	22	2	M39571
Pathway	REACTOME_KIDNEY_DEVELOPMENT	DLL1 JAG1	2.31e-03	46	22	2	M48243
Pathway	PID_SYNDECAN_1_PATHWAY	LAMA5 HGF	2.31e-03	46	22	2	M198
Pathway	WP_NOTCH_SIGNALING_PATHWAY	DLL1 JAG1	2.31e-03	46	22	2	MM15971
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	DLL1 JAG1	2.41e-03	47	22	2	M7946
Pathway	REACTOME_SIGNALING_BY_NOTCH3	DLL1 JAG1	2.62e-03	49	22	2	M618
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	SEMA7A PLXNB3	2.83e-03	51	22	2	MM14967
Pathway	KEGG_FOCAL_ADHESION	LAMA5 HGF LAMB4	3.50e-03	199	22	3	M7253
Pathway	WP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM	DLL1 JAG1	3.52e-03	57	22	2	M48326
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	DLL1 JAG1	3.65e-03	58	22	2	M29616
Pathway	PID_NOTCH_PATHWAY	DLL1 JAG1	3.77e-03	59	22	2	M17
Pathway	WP_NOTCH_SIGNALING_WP61	DLL1 JAG1	4.02e-03	61	22	2	M39540
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	SEMA7A PLXNB3	4.42e-03	64	22	2	M7923
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	LAMA5 JAG1	5.56e-03	72	22	2	M39403
Pathway	WP_AXON_GUIDANCE	SEMA7A SEMA5B	5.56e-03	72	22	2	M48335
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	LAMA5 JAG1	5.71e-03	73	22	2	MM15906
Pathway	REACTOME_SIGNALING_BY_NOTCH1	DLL1 JAG1	5.87e-03	74	22	2	M616
Pathway	REACTOME_INNATE_IMMUNE_SYSTEM	GRN PLD1 TNFRSF1B PIGR MUC4 ANO6	6.33e-03	1128	22	6	M1036
Pathway	KEGG_GLYCEROPHOSPHOLIPID_METABOLISM	PLA2G5 PLD1	6.34e-03	77	22	2	M9131
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS15 SEMA5B MUC4	6.61e-03	250	22	3	M27554
Pathway	REACTOME_SIGNALING_BY_MET	LAMA5 HGF	6.66e-03	79	22	2	M27643
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	DLL1 JAG1	7.16e-03	82	22	2	MM15922
Pathway	REACTOME_NEUTROPHIL_DEGRANULATION	GRN TNFRSF1B PIGR ANO6	7.42e-03	511	22	4	MM15330
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA5 LAMB4	7.50e-03	84	22	2	M3228
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA5 LAMB4	7.50e-03	84	22	2	M7098
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA7A SEMA5B PLXNB2 PLXNB3	6.48e-08	52	26	4	26633812
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	SEMA7A PLXNB2 PLXNB3	1.06e-07	13	26	3	10520995
Pubmed	The role of Pax2 in mouse inner ear development.	DLL1 DCT JAG1	2.50e-07	17	26	3	15242798
Pubmed	Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.	DLL1 SEMA5B JAG1	4.19e-07	20	26	3	15979417
Pubmed	Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines.	DLL1 JAG1	5.37e-07	2	26	2	15254769
Pubmed	In vitro effects of stromal cells expressing different levels of Jagged-1 and Delta-1 on the growth of primitive and intermediate CD34(+) cell subsets from human cord blood.	DLL1 JAG1	5.37e-07	2	26	2	21911304
Pubmed	Progranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina.	HGF GRN	5.37e-07	2	26	2	27030285
Pubmed	Specific Jagged-1 signal from bone marrow microenvironment is required for endothelial progenitor cell development for neovascularization.	DLL1 JAG1	5.37e-07	2	26	2	18591437
Pubmed	Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2.	GRN TNFRSF1B	5.37e-07	2	26	2	24703938
Pubmed	The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation.	DLL1 JAG1	5.37e-07	2	26	2	14769803
Pubmed	Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4⁺ Foxp3⁺ regulatory T cells.	GRN TNFRSF1B	5.37e-07	2	26	2	24383743
Pubmed	[Murine and human hematopoietic progenitor cultures grown on stromal layers expressing Notch ligands].	DLL1 JAG1	5.37e-07	2	26	2	28537242
Pubmed	Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.	DLL1 JAG1	5.37e-07	2	26	2	15486060
Pubmed	Human umbilical cord epithelial cells express Notch ligands Delta1 and Jagged1.	DLL1 JAG1	5.37e-07	2	26	2	19150223
Pubmed	Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear.	DLL1 JAG1	5.37e-07	2	26	2	10473135
Pubmed	Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes.	DLL1 JAG1	5.37e-07	2	26	2	18688026
Pubmed	Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis.	DLL1 JAG1	5.37e-07	2	26	2	16307184
Pubmed	The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.	DLL1 JAG1	5.37e-07	2	26	2	12826675
Pubmed	Human Jagged 1 mutants cause liver defect in Alagille syndrome by overexpression of hepatocyte growth factor.	HGF JAG1	5.37e-07	2	26	2	16403414
Pubmed	Circulating TNF-RII, IP-10 and HGF are associated with severity of COVID-19 in oncologic patients.	HGF TNFRSF1B	1.61e-06	3	26	2	38364458
Pubmed	Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines.	DLL1 JAG1	1.61e-06	3	26	2	12684674
Pubmed	Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia.	DLL1 JAG1	1.61e-06	3	26	2	20812035
Pubmed	The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.	GRN TNFRSF1B	1.61e-06	3	26	2	21393509
Pubmed	Both Notch1 and its ligands in B cells promote antibody production.	DLL1 JAG1	1.61e-06	3	26	2	28863329
Pubmed	Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development.	DLL1 JAG1	1.61e-06	3	26	2	8923452
Pubmed	A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.	DLL1 JAG1	1.61e-06	3	26	2	12482954
Pubmed	Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer.	DLL1 JAG1	1.61e-06	3	26	2	22080880
Pubmed	Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells.	DLL1 JAG1	1.61e-06	3	26	2	9716576
Pubmed	Notch signaling regulates arterial vasoreactivity through opposing functions of Jagged1 and Dll4 in the vessel wall.	DLL1 JAG1	1.61e-06	3	26	2	30168730
Pubmed	Jagged-1 Signaling in the Bone Marrow Microenvironment Promotes Endothelial Progenitor Cell Expansion and Commitment of CD133+ Human Cord Blood Cells for Postnatal Vasculogenesis.	DLL1 JAG1	1.61e-06	3	26	2	27846321
Pubmed	Transmission of survival signals through Delta-like 1 on activated CD4+ T cells.	DLL1 JAG1	1.61e-06	3	26	2	27659682
Pubmed	JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis.	DLL1 JAG1	1.61e-06	3	26	2	17947672
Pubmed	Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin.	PLXNB2 PLXNB3	1.61e-06	3	26	2	16122393
Pubmed	Group V secretory phospholipase A2 impairs endothelial protein C receptor-dependent protein C activation and accelerates thrombosis in vivo.	PLA2G5 PROC	1.61e-06	3	26	2	25069533
Pubmed	Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.	DLL1 JAG1	1.61e-06	3	26	2	15781650
Pubmed	Lack of Evidence for a Direct Interaction of Progranulin and Tumor Necrosis Factor Receptor-1 and Tumor Necrosis Factor Receptor-2 From Cellular Binding Studies.	GRN TNFRSF1B	1.61e-06	3	26	2	29740434
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	SEMA7A SEMA5B PLXNB2 PLXNB3	1.72e-06	117	26	4	17145500
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	SEMA7A SEMA5B PLXNB2 PLXNB3	2.31e-06	126	26	4	16284245
Pubmed	Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.	DLL1 JAG1	3.22e-06	4	26	2	20602435
Pubmed	Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.	DLL1 JAG1	3.22e-06	4	26	2	22390640
Pubmed	Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.	DLL1 JAG1	3.22e-06	4	26	2	9315665
Pubmed	No evidence for a functional role of bi-directional Notch signaling during angiogenesis.	DLL1 JAG1	3.22e-06	4	26	2	23300864
Pubmed	Keratinocyte expression of transgenic hepatocyte growth factor affects melanocyte development, leading to dermal melanocytosis.	HGF DCT	3.22e-06	4	26	2	10842060
Pubmed	Plexin-B family members demonstrate non-redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development.	PLXNB2 PLXNB3	3.22e-06	4	26	2	15147296
Pubmed	Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe.	DLL1 JAG1	3.22e-06	4	26	2	12036964
Pubmed	The Notch signalling pathway in hair growth.	DLL1 JAG1	3.22e-06	4	26	2	9858728
Pubmed	Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance.	DLL1 JAG1	3.22e-06	4	26	2	28699891
Pubmed	Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.	DLL1 JAG1	5.37e-06	5	26	2	11006133
Pubmed	Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation.	DLL1 JAG1	5.37e-06	5	26	2	11346656
Pubmed	Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila.	DLL1 JAG1	5.37e-06	5	26	2	9207795
Pubmed	PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner.	GRN TNFRSF1B	5.37e-06	5	26	2	25387791
Pubmed	Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains.	GRN TNFRSF1B	5.37e-06	5	26	2	24070898
Pubmed	Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.	DLL1 JAG1	5.37e-06	5	26	2	21602525
Pubmed	The extracellular matrix protein MAGP-2 interacts with Jagged1 and induces its shedding from the cell surface.	DLL1 JAG1	5.37e-06	5	26	2	15788413
Pubmed	Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.	PLXNB2 PLXNB3	5.37e-06	5	26	2	12183458
Pubmed	The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse.	DLL1 JAG1	5.37e-06	5	26	2	11713346
Pubmed	Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear.	DLL1 JAG1	5.37e-06	5	26	2	16495313
Pubmed	Interplay between scatter factor receptors and B plexins controls invasive growth.	PLXNB2 PLXNB3	5.37e-06	5	26	2	15184888
Pubmed	Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.	DLL1 JAG1	5.37e-06	5	26	2	12175503
Pubmed	Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells.	DLL1 JAG1	5.37e-06	5	26	2	19682396
Pubmed	Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.	DLL1 JAG1	5.37e-06	5	26	2	20554499
Pubmed	Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.	DLL1 JAG1	8.05e-06	6	26	2	10958687
Pubmed	Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo.	DLL1 JAG1	8.05e-06	6	26	2	9272948
Pubmed	MEK, p38, and PI-3K mediate cross talk between EGFR and TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells.	HGF TNFRSF1B	8.05e-06	6	26	2	19692652
Pubmed	Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.	DLL1 JAG1	8.05e-06	6	26	2	19603167
Pubmed	The CD46-Jagged1 interaction is critical for human TH1 immunity.	DLL1 JAG1	8.05e-06	6	26	2	23086448
Pubmed	Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.	DLL1 JAG1	8.05e-06	6	26	2	19217325
Pubmed	Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands.	DLL1 JAG1	8.05e-06	6	26	2	28089369
Pubmed	Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ+CD8αα+ T cells.	DLL1 JAG1	8.05e-06	6	26	2	31071093
Pubmed	Human ligands of the Notch receptor.	DLL1 JAG1	1.13e-05	7	26	2	10079256
Pubmed	Impaired expression of Notch signaling genes in aged human skeletal muscle.	DLL1 JAG1	1.13e-05	7	26	2	17301032
Pubmed	The distribution of Notch receptors and their ligands during articular cartilage development.	DLL1 JAG1	1.13e-05	7	26	2	12846471
Pubmed	Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39.	HGF DCT	1.13e-05	7	26	2	32152201
Pubmed	Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.	DLL1 JAG1	1.13e-05	7	26	2	24711412
Pubmed	Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.	DLL1 JAG1	1.13e-05	7	26	2	21238454
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	LAMA5 PIGR VWA2 MUC4 ANO6	1.29e-05	417	26	5	19199708
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNB2 PLXNB3	1.50e-05	8	26	2	15661641
Pubmed	Complementary expression patterns of retinoid acid-synthesizing and -metabolizing enzymes in pre-natal mouse inner ear structures.	DCT JAG1	1.50e-05	8	26	2	15161092
Pubmed	Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis.	DLL1 JAG1	1.50e-05	8	26	2	17960184
Pubmed	An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.	DLL1 PLXNB2	1.50e-05	8	26	2	21559415
Pubmed	Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.	DLL1 JAG1	1.50e-05	8	26	2	15465493
Pubmed	Dual role of laminin‑511 in regulating melanocyte migration and differentiation.	LAMA5 DCT	1.50e-05	8	26	2	30273664
Pubmed	Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.	DLL1 JAG1	1.50e-05	8	26	2	24647000
Pubmed	Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.	LAMA5 VWA2	1.50e-05	8	26	2	19651211
Pubmed	Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.	DLL1 JAG1	1.50e-05	8	26	2	9858718
Pubmed	Notch/Delta expression in the developing mouse lung.	DLL1 JAG1	1.50e-05	8	26	2	11044610
Pubmed	Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.	DLL1 JAG1	1.93e-05	9	26	2	11118901
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	DLL1 JAG1	1.93e-05	9	26	2	16245338
Pubmed	Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.	DLL1 JAG1	1.93e-05	9	26	2	28714968
Pubmed	Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1.	DLL1 JAG1	1.93e-05	9	26	2	15574878
Pubmed	Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.	DLL1 JAG1	1.93e-05	9	26	2	11937492
Pubmed	Monitoring Notch1 activity in development: evidence for a feedback regulatory loop.	DLL1 JAG1	1.93e-05	9	26	2	17685488
Pubmed	Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.	DLL1 JAG1	1.93e-05	9	26	2	20727173
Pubmed	Notch signaling is essential for vascular morphogenesis in mice.	DLL1 JAG1	1.93e-05	9	26	2	10837027
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	DLL1 JAG1	2.41e-05	10	26	2	23665443
Pubmed	Jag1-Notch cis-interaction determines cell fate segregation in pancreatic development.	DLL1 JAG1	2.41e-05	10	26	2	36681690
Pubmed	Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.	TNFRSF1B DLL1	2.41e-05	10	26	2	34519339
Pubmed	Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.	DLL1 JAG1	2.41e-05	10	26	2	24015274
Pubmed	A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice.	DLL1 JAG1	2.41e-05	10	26	2	31590629
Pubmed	Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates.	DLL1 JAG1	2.41e-05	10	26	2	24715457
Interaction	MFAP5 interactions	LAMA5 EMILIN3 GRN DLL1 JAG1	5.93e-09	52	26	5	int:MFAP5
Interaction	FBXO2 interactions	LAMA5 EMILIN3 GRN MEGF8 PLXNB2 ANO6 JAG1	6.56e-07	411	26	7	int:FBXO2
Interaction	SLURP1 interactions	LAMA5 GRN MEGF8 PLXNB2	3.31e-05	144	26	4	int:SLURP1
Interaction	LGALS1 interactions	LAMA5 GRN PIGR PLXNB2 JAG1	5.83e-05	332	26	5	int:LGALS1
Interaction	NOTCH2 interactions	ADAMTS15 GRN DLL1 PIGR JAG1	1.82e-04	423	26	5	int:NOTCH2
Interaction	NEURL1 interactions	DLL1 JAG1	2.15e-04	17	26	2	int:NEURL1
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PLA2G5 C1orf159 TNFRSF1B	6.55e-03	681	26	3	chr1p36
GeneFamily	Plexins	PLXNB2 PLXNB3	4.17e-05	9	20	2	683
GeneFamily	Laminin subunits	LAMA5 LAMB4	7.62e-05	12	20	2	626
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA7A SEMA5B	2.18e-04	20	20	2	736
GeneFamily	Phospholipases	PLA2G5 PLD1	9.75e-04	42	20	2	467
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	TNFRSF1B SEMA7A JAG1	8.89e-03	394	20	3	471
Coexpression	NABA_MATRISOME	ADAMTS15 LAMA5 HGF EMILIN3 LAMB4 MEGF8 SEMA7A SEMA5B PLXNB2 VWA2 MUC4 MEGF10 PLXNB3	3.04e-12	1026	26	13	M5889
Coexpression	NABA_MATRISOME	ADAMTS15 LAMA5 HGF EMILIN3 MEGF8 SEMA7A SEMA5B PLXNB2 VWA2 MUC4 MEGF10 PLXNB3	5.76e-11	1008	26	12	MM17056
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS15 HGF MEGF8 SEMA7A SEMA5B PLXNB2 MUC4 MEGF10 PLXNB3	2.15e-08	738	26	9	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS15 HGF MEGF8 SEMA7A SEMA5B PLXNB2 MUC4 MEGF10 PLXNB3	2.50e-08	751	26	9	M5885
Coexpression	NABA_ECM_AFFILIATED	SEMA7A SEMA5B PLXNB2 MUC4 PLXNB3	4.44e-07	158	26	5	MM17063
Coexpression	NABA_ECM_AFFILIATED	SEMA7A SEMA5B PLXNB2 MUC4 PLXNB3	6.37e-07	170	26	5	M5880
Coexpression	SERVITJA_ISLET_HNF1A_TARGETS_DN	PIGR DCT MUC4 PROC	4.09e-06	110	26	4	M2396
Coexpression	SERVITJA_ISLET_HNF1A_TARGETS_DN	PIGR DCT MUC4 PROC	5.97e-06	121	26	4	MM935
Coexpression	HUTTMANN_B_CLL_POOR_SURVIVAL_UP	LAMA5 C1orf159 GRN PLD1 TNFRSF1B	7.87e-06	284	26	5	M19993
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA5 EMILIN3 LAMB4 VWA2	3.98e-05	196	26	4	M3008
Coexpression	PLASARI_TGFB1_TARGETS_10HR_UP	SEMA7A ALS2CL MEGF10 JAG1	3.98e-05	196	26	4	M2445
Coexpression	PLASARI_TGFB1_TARGETS_10HR_UP	SEMA7A ALS2CL MEGF10 JAG1	4.06e-05	197	26	4	MM1320
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL1 JAG1	1.13e-04	16	26	2	M2207
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL1 JAG1	1.13e-04	16	26	2	MM1296
Coexpression	NABA_CORE_MATRISOME	LAMA5 EMILIN3 LAMB4 VWA2	1.48e-04	275	26	4	M5884
Coexpression	BRAUNE_GEIST_20_GENE_NOTCH_SIG_BREAST_CANCER	SEMA5B JAG1	1.78e-04	20	26	2	M48357
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	LAMA5 GRN PLD1 TNFRSF1B PIGR ANO6 JAG1	1.85e-04	1276	26	7	M39173
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_GRIA2_POS_ARTERIAL_ENDO_CELL	LAMA5 TNFRSF1B JAG1	1.99e-04	115	26	3	M45752
Coexpression	GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_DN	PLA2G5 MEGF8 MEGF10	2.37e-04	122	26	3	M6861
Coexpression	VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN	LAMA5 HGF DLL1	3.19e-04	135	26	3	M5825
Coexpression	TABULA_MURIS_SENIS_LIVER_HEPATOCYTE_AGEING	GRN PIGR PROC	4.09e-04	147	26	3	MM3753
Coexpression	RYAN_MANTLE_CELL_LYMPHOMA_NOTCH_DIRECT_UP	GRN TNFRSF1B SEMA7A	4.17e-04	148	26	3	M39016
Coexpression	HALLMARK_NOTCH_SIGNALING	DLL1 JAG1	4.61e-04	32	26	2	M5903
Coexpression	VERHAAK_GLIOBLASTOMA_CLASSICAL	PLA2G5 MEGF8 JAG1	5.33e-04	161	26	3	M2121
Coexpression	VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	HGF DLL1 JAG1	5.53e-04	163	26	3	M12112
Coexpression	GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP	TLE6 SEMA7A ANO6	6.91e-04	176	26	3	M7725
Coexpression	GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP	GRN SEMA7A PLXNB2	6.91e-04	176	26	3	M8881
Coexpression	NABA_BASEMENT_MEMBRANES	LAMA5 LAMB4	7.21e-04	40	26	2	M5887
Coexpression	CUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE	GRN PLXNB2 JAG1	7.25e-04	179	26	3	M39308
Coexpression	HALLMARK_WNT_BETA_CATENIN_SIGNALING	DLL1 JAG1	7.95e-04	42	26	2	M5895
Coexpression	JOHNSTONE_PARVB_TARGETS_3_UP	EMILIN3 GRN PLD1 JAG1	8.23e-04	433	26	4	M2240
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA5 EMILIN3 VWA2	8.75e-04	191	26	3	MM17059
Coexpression	GSE2706_LPS_VS_R848_AND_LPS_2H_STIM_DC_UP	MEGF10 PLXNB3 JAG1	8.75e-04	191	26	3	M4722
Coexpression	LEE_BMP2_TARGETS_UP	GRN PLD1 PIGR PLXNB2 JAG1	9.01e-04	780	26	5	M2324
Coexpression	KARLSSON_TGFB1_TARGETS_DN	LAMA5 GRN PLXNB2	9.16e-04	194	26	3	M2081
Coexpression	GSE3982_EOSINOPHIL_VS_BASOPHIL_UP	PLA2G5 C1orf159 JAG1	9.43e-04	196	26	3	M5413
Coexpression	GSE34156_UNTREATED_VS_24H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP	GRN PLXNB2 MUC4	9.43e-04	196	26	3	M8683
Coexpression	GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP	PLD1 TNFRSF1B DLL1	9.43e-04	196	26	3	M8714
Coexpression	GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN	GRN PLXNB2 ANO6	9.57e-04	197	26	3	M8686
Coexpression	GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP	HGF PLD1 JAG1	9.71e-04	198	26	3	M8158
Coexpression	GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN	PLD1 TNFRSF1B DLL1	9.71e-04	198	26	3	M8723
Coexpression	GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP	LAMA5 GRN JAG1	9.85e-04	199	26	3	M9410
Coexpression	GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN	PLD1 TNFRSF1B DLL1	9.85e-04	199	26	3	M8721
Coexpression	GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN	GRN ANO6 PLXNB3	1.00e-03	200	26	3	M8574
Coexpression	GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN	GRN PLD1 PLXNB2	1.00e-03	200	26	3	M5104
Coexpression	GSE339_CD4POS_VS_CD8POS_DC_UP	TNFRSF1B SEMA7A PLXNB2	1.00e-03	200	26	3	M5108
Coexpression	GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP	MEGF8 PLXNB2 ANO6	1.00e-03	200	26	3	M328
Coexpression	GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN	TLE6 PLD1 SEMA7A	1.00e-03	200	26	3	M7469
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN	GRN TNFRSF1B PLXNB2	1.00e-03	200	26	3	M4496
Coexpression	GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN	GRN TNFRSF1B PLXNB2	1.00e-03	200	26	3	M4480
Coexpression	GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN	GRN TNFRSF1B PLXNB2	1.00e-03	200	26	3	M4486
Coexpression	GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN	PLD1 DLL1 PLXNB2	1.00e-03	200	26	3	M8217
Coexpression	GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_UP	HGF PLD1 SEMA7A	1.00e-03	200	26	3	M8222
Coexpression	GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_DN	ADAMTS15 HGF SEMA7A	1.00e-03	200	26	3	M4375
Coexpression	GSE20715_0H_VS_6H_OZONE_LUNG_DN	LAMA5 PLD1 PIGR	1.00e-03	200	26	3	M4365
Coexpression	DESCARTES_FETAL_HEART_SMOOTH_MUSCLE_CELLS	PLA2G5 SEMA5B	1.04e-03	48	26	2	M40200
Coexpression	LEE_BMP2_TARGETS_UP	GRN PLD1 PIGR PLXNB2 JAG1	1.04e-03	805	26	5	MM1067
Coexpression	KARLSSON_TGFB1_TARGETS_DN	LAMA5 GRN PLXNB2	1.13e-03	209	26	3	MM1058
CoexpressionAtlas	DevelopingGonad_P2_testes_emap-30171_k-means-cluster#4_top-relative-expression-ranked_200	PLA2G5 SEMA7A SEMA5B	6.16e-05	63	26	3	gudmap_developingGonad_P2_testes_200_k4
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000	TLE6 EMILIN3 PLD1 DLL1 ALS2CL MUC4 ANO6	1.27e-04	973	26	7	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlas	Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3	HGF GRN PLD1 PLXNB2 JAG1	1.68e-04	438	26	5	GSM605850_500
CoexpressionAtlas	Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5	LAMA5 DLL1 SEMA7A PLXNB2 JAG1	2.02e-04	456	26	5	GSM777032_500
CoexpressionAtlas	Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4	LAMA5 DLL1 SEMA7A PLXNB2 JAG1	2.09e-04	459	26	5	GSM777037_500
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_500	PLA2G5 SEMA7A SEMA5B	2.29e-04	98	26	3	gudmap_developingGonad_e14.5_ testes_500_k5
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#5_top-relative-expression-ranked_100	DLL1 JAG1	2.43e-04	19	26	2	gudmap_developingKidney_e14.5 whole kidney - wildtype_100_k5
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500	PLD1 DLL1 ALS2CL MUC4 ANO6	2.82e-04	490	26	5	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRN TNFRSF1B MUC4 PROC	2.17e-06	160	26	4	2586035a1380bc56814a6db0ca773ad835666042
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRN TNFRSF1B MUC4 PROC	2.17e-06	160	26	4	3b5a335786165391fe983ff0585cd508733793aa
ToppCell	wk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	LAMB4 PLD1 DLL1 JAG1	3.61e-06	182	26	4	6bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	HGF PLA2G5 SEMA5B JAG1	3.77e-06	184	26	4	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	PLA2G5 SEMA7A ALS2CL MEGF10	4.02e-06	187	26	4	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 PIGR ALS2CL MUC4	4.02e-06	187	26	4	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS15 PLA2G5 SEMA5B JAG1	4.19e-06	189	26	4	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	HGF PLA2G5 SEMA5B JAG1	4.37e-06	191	26	4	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	Control-B_intermediate-10\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GRN TNFRSF1B SEMA7A PIGR	4.46e-06	192	26	4	224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF PLA2G5 SEMA5B JAG1	4.94e-06	197	26	4	6668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF PLA2G5 SEMA5B JAG1	4.94e-06	197	26	4	7c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS15 HGF PLA2G5 JAG1	5.04e-06	198	26	4	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLD1 DCT PLXNB3	4.49e-05	119	26	3	ec3af1253f03b3ec403f73243237acf08ad56789
ToppCell	NS-moderate-d_16-33-Epithelial-unknown_epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LAMA5 PLXNB2 MUC4	6.82e-05	137	26	3	03e124901a0e85b59b6882bbafab568b50907e8b
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DLL1 DCT PLXNB3	7.12e-05	139	26	3	a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ADAMTS15 EMILIN3 MEGF10	7.28e-05	140	26	3	5623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAMA5 SEMA7A PROC	7.75e-05	143	26	3	d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAMA5 SEMA7A PROC	7.75e-05	143	26	3	8900b92a24289204b9ec7baccc11594fec7694f1
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TLE6 DCT PLXNB3	8.24e-05	146	26	3	a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DCT MEGF10 PLXNB3	8.58e-05	148	26	3	d60f93311cfa718d026a0dbf61771bbbcbb79146
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DCT MEGF10 PLXNB3	8.58e-05	148	26	3	44128692824ca419fface0af41099c17135933ce
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TLE6 DCT PLXNB3	8.93e-05	150	26	3	70ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MEGF8 ALS2CL MUC4	9.47e-05	153	26	3	e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 EMILIN3 PROC	9.65e-05	154	26	3	46155f36d3983f637b55d7525b675c8828f6ab2e
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 EMILIN3 PROC	9.65e-05	154	26	3	71ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRN TNFRSF1B PLXNB2	1.04e-04	158	26	3	1635a85fc73c544028418087f36d28957dd4f458
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRN TNFRSF1B PLXNB2	1.04e-04	158	26	3	80841dadfa53bcde36a3e486408a095f78e772eb
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIGR PLXNB2 MUC4	1.06e-04	159	26	3	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF1B PLXNB2 PLXNB3	1.10e-04	161	26	3	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	facs-Marrow-T_cells-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF1B PLXNB2 PLXNB3	1.14e-04	163	26	3	30cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCell	facs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF1B PLXNB2 PLXNB3	1.14e-04	163	26	3	ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	PLD1 DLL1 JAG1	1.20e-04	166	26	3	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	PLD1 DLL1 JAG1	1.23e-04	167	26	3	3ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell	3'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLL1 MUC4 PROC	1.25e-04	168	26	3	2163e6774eb7a3d010422e4d59be5e45b4158329
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIGR MUC4 MEGF10	1.27e-04	169	26	3	40b557549fe08c5dc9dba359af35993d68d1640a
ToppCell	Club_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	PIGR MUC4 MEGF10	1.27e-04	169	26	3	03b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF EMILIN3 LAMB4	1.27e-04	169	26	3	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	droplet-Marrow-BM-1m-Myeloid-monocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRN TNFRSF1B PLXNB2	1.27e-04	169	26	3	8066b4c02c97d00034802cff2b39799ef44cc904
ToppCell	droplet-Fat-Scat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS15 GRN PLXNB2	1.29e-04	170	26	3	de722bea7527d6ad11b69f8e9589638f52854beb
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	HGF C1orf159 DLL1	1.29e-04	170	26	3	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	SEMA7A MEGF10 PROC	1.29e-04	170	26	3	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DLL1 SEMA7A JAG1	1.29e-04	170	26	3	55fe16d98ea284d05fb899888e4569c685644c7b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C1orf159 VWA2 MEGF10	1.29e-04	170	26	3	fed8e982d2ce234c59d4016432ed8941df36df27
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLA2G5 SEMA5B JAG1	1.29e-04	170	26	3	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	HGF C1orf159 DLL1	1.34e-04	172	26	3	b66dbfff5e4f53ca8ece91ff9c5dc66a71f07c63
ToppCell	facs-BAT-Fat-18m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRN TNFRSF1B PLXNB2	1.34e-04	172	26	3	36fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRN TNFRSF1B PLXNB2	1.36e-04	173	26	3	807183fc23478da9451906dacd88de4e73112e0d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNB2 ANO6 JAG1	1.36e-04	173	26	3	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNB2 ANO6 JAG1	1.36e-04	173	26	3	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRN TNFRSF1B PLXNB2	1.36e-04	173	26	3	2e683ec555dc0036875e0f5674dcc5e93ead205d
ToppCell	Dendritic_Cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	TNFRSF1B SEMA5B PROC	1.36e-04	173	26	3	ddb900ef4abeabe2e59db1009efc337e35d301fe
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SEMA7A ALS2CL VWA2	1.38e-04	174	26	3	40bb87d219aafab0357ab0d797efd38085fc0312
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIGR MUC4 PLXNB3	1.38e-04	174	26	3	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	10x5'-blood-Myeloid_Dendritic\|blood / Manually curated celltypes from each tissue	GRN MEGF10 PROC	1.41e-04	175	26	3	1c48eec300d5a6d4a810947b995af3b8c0a5a601
ToppCell	Posterior_cortex-Macroglia\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DCT MEGF10 PLXNB3	1.41e-04	175	26	3	8bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCell	ILEUM-inflamed-(3)_pDC\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GRN SEMA7A PROC	1.43e-04	176	26	3	b9f847dd55703e413f3cd815eef5724fffaf13b3
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLA2G5 SEMA5B JAG1	1.43e-04	176	26	3	8b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCell	Club_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	LAMA5 PIGR MUC4	1.43e-04	176	26	3	88c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|World / Disease state, Lineage and Cell class	LAMA5 SEMA7A ALS2CL	1.46e-04	177	26	3	22b7cda748cf5e665be54ca5bae89f0c130d5e7f
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GRN TNFRSF1B SEMA7A	1.48e-04	178	26	3	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LAMB4 PIGR MUC4	1.48e-04	178	26	3	9a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	LAMB4 PIGR MUC4	1.48e-04	178	26	3	19b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLL1 SEMA7A ANO6	1.48e-04	178	26	3	09a215a0d6e98e4bb920cabda12af08ff4de3c98
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAMB4 PIGR MUC4	1.48e-04	178	26	3	b413a634283550fa224db7d0d05956e3f64694a1
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAMB4 PIGR MUC4	1.48e-04	178	26	3	49a2271718637522f74334068d252963ee13b1ce
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRN SEMA7A PROC	1.51e-04	179	26	3	ba64bfb757d6e3be631ee95abfa24b47861f6a14
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS15 PLA2G5 SEMA5B	1.56e-04	181	26	3	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	PLA2G5 SEMA5B JAG1	1.56e-04	181	26	3	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLA2G5 SEMA5B JAG1	1.56e-04	181	26	3	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRN PLXNB2 PROC	1.56e-04	181	26	3	c8286a7ac8e3cc5aa7e92b043a08435294ea686f
ToppCell	droplet-Thymus-nan-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRN PLD1 MEGF8	1.58e-04	182	26	3	f6717e97e87513384149800c9fd8dea821ab9393
ToppCell	droplet-Thymus-nan-18m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRN PLD1 MEGF8	1.58e-04	182	26	3	c33b0d532822186a1e8e645500347972468718c0
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	PLA2G5 SEMA5B JAG1	1.61e-04	183	26	3	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	GRN PLXNB2 PROC	1.61e-04	183	26	3	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.61e-04	183	26	3	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	PBMC-Convalescent-Myeloid-cDC\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	GRN PIGR PROC	1.63e-04	184	26	3	5535b85b3ad3d0c0392d5884fdc2939c7e1b1c3e
ToppCell	myeloid-Dendritic_cell-Plasmacytoid_dendritic_cell\|World / Lineage, cell class and subclass	PLA2G5 GRN PROC	1.63e-04	184	26	3	11619778bc773ecd1a9867330be04deaf324f31e
ToppCell	Mild/Remission-B_intermediate-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	GRN TNFRSF1B SEMA7A	1.63e-04	184	26	3	3d4864605c812862cf8926e02370eea3b8ccf32f
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	PLD1 MEGF10 JAG1	1.63e-04	184	26	3	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	COVID-19_Convalescent-Myeloid-cDC\|COVID-19_Convalescent / Disease group, lineage and cell class	GRN PIGR PROC	1.63e-04	184	26	3	ad6e910eaebe841a68a5f2f329d43dafc5db158a
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.63e-04	184	26	3	5939527d24d299e562e707469c9123890edd76be
ToppCell	PBMC-Convalescent-Myeloid-cDC-cDC\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GRN PIGR PROC	1.63e-04	184	26	3	9d678b24532b7763f2e73f7ccb496259977c5204
ToppCell	PBMC-Convalescent-Myeloid-cDC-cDC-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GRN PIGR PROC	1.63e-04	184	26	3	383374ad17bd322b8d703a22e475d34ca7b2e6b6
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.63e-04	184	26	3	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DCT MEGF10 PLXNB3	1.63e-04	184	26	3	a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	PLA2G5 SEMA5B JAG1	1.66e-04	185	26	3	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.66e-04	185	26	3	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EMILIN3 MEGF10 PLXNB3	1.66e-04	185	26	3	f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.66e-04	185	26	3	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	5'-Adult-LargeIntestine-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EMILIN3 MEGF10 PLXNB3	1.66e-04	185	26	3	317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell	5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EMILIN3 MEGF10 PLXNB3	1.66e-04	185	26	3	7bb8fdfe04f85d25056380ec58222366de323a21
ToppCell	facs-BAT-Fat-24m-Epithelial-Epcam+\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIGR VWA2 MUC4	1.69e-04	186	26	3	b18d7398279a2d42414318aeb70514fd402f5a0a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.69e-04	186	26	3	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF PLA2G5 SEMA5B	1.69e-04	186	26	3	1e3ab663e4756975db6d802b2c6c054a94a79393
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA5 PIGR MUC4	1.69e-04	186	26	3	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.69e-04	186	26	3	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	PLA2G5 SEMA5B JAG1	1.69e-04	186	26	3	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.69e-04	186	26	3	d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF PLA2G5 SEMA5B	1.71e-04	187	26	3	b8f88599e22b9b345c7ec3bbecd87a8b2a033f9f
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLD1 MEGF10 PLXNB3	1.71e-04	187	26	3	b71d0cd91bc98e020757c1d071a13ad48d718bcf
Computational	Genes in the cancer module 346.	PLA2G5 PLD1	2.79e-04	17	16	2	MODULE_346
Computational	Genes in the cancer module 408.	PLA2G5 PLD1	3.13e-04	18	16	2	MODULE_408
Computational	Genes in the cancer module 417.	PLA2G5 PLD1	4.72e-04	22	16	2	MODULE_417
Drug	Picrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A	PLA2G5 PLD1 PIGR MUC4 PROC	2.43e-06	194	26	5	4260_UP
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A	HGF MEGF8 PIGR DCT JAG1	2.49e-06	195	26	5	6035_UP
Drug	Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A	LAMB4 PLD1 TNFRSF1B MEGF8 SEMA7A	2.62e-06	197	26	5	5633_UP
Drug	rebamipide	HGF TNFRSF1B JAG1	2.65e-05	51	26	3	CID000005042
Drug	VTEs	GRN PROC	5.61e-05	10	26	2	CID000006516
Drug	Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A	PLA2G5 LAMB4 MEGF8 MUC4	6.60e-05	194	26	4	5610_UP
Drug	chlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A	LAMB4 PLD1 SEMA7A PROC	6.73e-05	195	26	4	6176_UP
Drug	AC1L1G72	LAMA5 LAMB4	6.85e-05	11	26	2	CID000003553
Drug	Azathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A	PLA2G5 PLD1 MEGF8 ALS2CL	6.86e-05	196	26	4	5627_UP
Drug	Gemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A	PLD1 MEGF8 DCT JAG1	7.00e-05	197	26	4	5069_UP
Drug	Amrinone [60719-84-8]; Up 200; 21.4uM; PC3; HT_HG-U133A	HGF PLA2G5 LAMB4 PROC	7.00e-05	197	26	4	4488_UP
Drug	Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; MCF7; HT_HG-U133A	HGF LAMB4 SEMA7A ALS2CL	7.00e-05	197	26	4	6094_UP
Drug	Evoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A	TLE6 HGF SEMA7A PIGR	7.00e-05	197	26	4	3681_UP
Drug	Myosmine [532-12-7]; Up 200; 27.4uM; PC3; HT_HG-U133A	LAMB4 PLD1 MEGF8 PIGR	7.00e-05	197	26	4	3737_UP
Drug	CP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A	TNFRSF1B PIGR DCT JAG1	7.14e-05	198	26	4	3909_UP
Drug	Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A	HGF PLA2G5 MEGF8 PIGR	7.14e-05	198	26	4	5067_UP
Drug	Tropicamide [1508-75-4]; Up 200; 14uM; PC3; HT_HG-U133A	PLD1 MEGF8 PIGR DCT	7.14e-05	198	26	4	4280_UP
Drug	Practolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A	LAMB4 PLD1 PIGR MUC4	7.14e-05	198	26	4	4603_UP
Drug	Indapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	HGF LAMB4 PIGR MUC4	7.14e-05	198	26	4	3970_UP
Drug	Ofloxacin [82419-36-1]; Up 200; 11uM; MCF7; HT_HG-U133A	HGF LAMB4 PIGR DCT	7.28e-05	199	26	4	2302_UP
Drug	Dacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A	HGF LAMB4 PIGR JAG1	7.28e-05	199	26	4	6816_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A	HGF PIGR DCT MUC4	7.28e-05	199	26	4	6444_UP
Drug	chondroitin sulfate	LAMA5 HGF SEMA5B PLXNB3 PROC	9.21e-05	413	26	5	CID000024766
Drug	K00077	HGF PLD1 TNFRSF1B PLXNB2	1.07e-04	220	26	4	CID006419759
Drug	AC1O0UVD	HGF TNFRSF1B PROC	1.10e-04	82	26	3	CID006102706
Drug	Rgd Peptide	LAMA5 LAMB4 GRN SEMA7A	1.48e-04	239	26	4	CID000104802
Disease	temporal arteritis (is_marker_for)	DLL1 JAG1	1.56e-05	7	26	2	DOID:13375 (is_marker_for)
Disease	biliary tract benign neoplasm (is_marker_for)	HGF MUC4	1.56e-05	7	26	2	DOID:0050625 (is_marker_for)
Disease	polymyositis (is_marker_for)	HGF TNFRSF1B	4.09e-05	11	26	2	DOID:0080745 (is_marker_for)
Disease	cholangiocarcinoma (biomarker_via_orthology)	HGF MUC4	5.79e-05	13	26	2	DOID:4947 (biomarker_via_orthology)
Disease	corpus callosum volume measurement	HGF DLL1 JAG1	9.28e-05	100	26	3	EFO_0010299
Disease	ankylosing spondylitis (is_implicated_in)	TNFRSF1B ANO6	1.26e-04	19	26	2	DOID:7147 (is_implicated_in)
Disease	coronary atherosclerosis measurement, traffic air pollution measurement	PIGR MEGF10	1.55e-04	21	26	2	EFO_0007908, EFO_0007938
Disease	pre-eclampsia (is_implicated_in)	TNFRSF1B PROC	2.21e-04	25	26	2	DOID:10591 (is_implicated_in)
Disease	myocardial infarction (is_marker_for)	HGF PROC	3.88e-04	33	26	2	DOID:5844 (is_marker_for)
Disease	Thrombus	HGF PROC	7.55e-04	46	26	2	C0087086
Disease	multiple sclerosis (is_marker_for)	GRN JAG1	8.56e-04	49	26	2	DOID:2377 (is_marker_for)
Disease	developmental disorder of mental health (implicated_via_orthology)	PLXNB2 PLXNB3	8.56e-04	49	26	2	DOID:0060037 (implicated_via_orthology)
Disease	Thrombosis	HGF PROC	8.56e-04	49	26	2	C0040053
Disease	Schizophrenia	GRN TNFRSF1B ALS2CL MEGF10 JAG1	9.25e-04	883	26	5	C0036341
Disease	cholangiocarcinoma (is_marker_for)	HGF MUC4	1.46e-03	64	26	2	DOID:4947 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GRLCQATYEGEWCRG	ALS2CL	351	Q60I27
PDGYTCCRLQSGAWG	GRN	291	P28799
DNRQGWACCPYRQGV	GRN	536	P28799
KWDPYGPCSRTCGGG	ADAMTS15	521	Q8TE58
WLGKYRNEECDPGGC	ANO6	586	Q4KMQ2
TCYCSPGWKGARCDQ	MEGF10	816	Q96KG7
RGGVCCSYGPWGEFR	MUC4	4616	Q99102
RAANPDYRCAWCGGQ	PLXNB2	771	O15031
GCLWCADGQPACRYG	PLXNB3	806	Q9ULL4
CRKRGPGFCDECQDW	MEGF8	1171	Q7Z7M0
YCRNPRGEEGGPWCF	HGF	176	P14210
RDCSRCATGYWGFPN	LAMA5	1466	O15230
CYCGWGGRGTPKDGT	PLA2G5	46	P39877
GWRRCSCAPGYKLGD	PROC	156	P04070
GECKCRVGWQGRYCD	DLL1	241	O00548
CDRCADGYWNLVPGR	LAMB4	1061	A4D0S4
AEYRQCRWGPKCPGT	EMILIN3	81	Q9NT22
SLCGPGCYRRWNADG	C1orf159	81	Q96HA4
KLPGDCRCQYGWQGL	JAG1	246	P78504
PGLNCCGQGRACYRW	PLD1	236	Q13393
NGSYRCKCRDGWEGP	VWA2	731	Q5GFL6
SRDPYCGWDQGRCIS	SEMA7A	506	O75326
SQGACLGARDPYCGW	SEMA5B	561	Q9P283
TRKYWCRQGARGGCI	PIGR	51	P01833
CGDCKFGWTGPNCER	DCT	106	P40126
RPGWYCALSKQEGCR	TNFRSF1B	121	P20333
GYNIWTGGPDACLRC	TLE6	431	Q9H808