Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	notochord regression	GLI1 GLI2	2.80e-06	2	35	2	GO:0060032
GeneOntologyBiologicalProcess	smoothened signaling pathway involved in ventral spinal cord interneuron specification	GLI2 GLI3	8.38e-06	3	35	2	GO:0021775
GeneOntologyBiologicalProcess	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	GLI2 GLI3	8.38e-06	3	35	2	GO:0021776
GeneOntologyBiologicalProcess	smoothened signaling pathway involved in ventral spinal cord patterning	GLI2 GLI3	8.38e-06	3	35	2	GO:0021910
GeneOntologyBiologicalProcess	proximal/distal pattern formation	GLI1 GLI2 GLI3	3.34e-05	37	35	3	GO:0009954
GeneOntologyBiologicalProcess	ventral midline development	GLI1 GLI2	4.18e-05	6	35	2	GO:0007418
GeneOntologyBiologicalProcess	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	GLI2 GLI3	5.84e-05	7	35	2	GO:0060831
GeneOntologyBiologicalProcess	cell fate specification involved in pattern specification	GLI2 GLI3	7.78e-05	8	35	2	GO:0060573
GeneOntologyBiologicalProcess	ventral spinal cord interneuron specification	GLI2 GLI3	7.78e-05	8	35	2	GO:0021521
GeneOntologyBiologicalProcess	hindgut morphogenesis	GLI2 GLI3	1.00e-04	9	35	2	GO:0007442
GeneOntologyBiologicalProcess	hindgut development	GLI2 GLI3	1.25e-04	10	35	2	GO:0061525
GeneOntologyBiologicalProcess	digestive tract morphogenesis	GLI1 GLI2 GLI3	1.36e-04	59	35	3	GO:0048546
GeneOntologyBiologicalProcess	spinal cord motor neuron cell fate specification	GLI2 GLI3	1.52e-04	11	35	2	GO:0021520
GeneOntologyBiologicalProcess	ventral spinal cord interneuron fate commitment	GLI2 GLI3	1.83e-04	12	35	2	GO:0060579
GeneOntologyBiologicalProcess	cell fate commitment involved in pattern specification	GLI2 GLI3	1.83e-04	12	35	2	GO:0060581
GeneOntologyBiologicalProcess	notochord morphogenesis	GLI1 GLI2	1.83e-04	12	35	2	GO:0048570
GeneOntologyBiologicalProcess	ventral spinal cord interneuron differentiation	GLI2 GLI3	2.51e-04	14	35	2	GO:0021514
GeneOntologyBiologicalProcess	anatomical structure regression	GLI1 GLI2	5.21e-04	20	35	2	GO:0060033
GeneOntologyBiologicalProcess	spinal cord dorsal/ventral patterning	GLI2 GLI3	5.21e-04	20	35	2	GO:0021513
GeneOntologyBiologicalProcess	spinal cord patterning	GLI2 GLI3	6.33e-04	22	35	2	GO:0021511
GeneOntologyBiologicalProcess	intracellular transport	POM121L2 AHCYL1 ANK3 VPS51 TRARG1 ARHGAP21 DCLK1 GLI3 PPP1R12A	6.81e-04	1496	35	9	GO:0046907
GeneOntologyBiologicalProcess	regulation of smoothened signaling pathway	GLI1 GLI2 GLI3	7.45e-04	105	35	3	GO:0008589
GeneOntologyBiologicalProcess	notochord development	GLI1 GLI2	7.54e-04	24	35	2	GO:0030903
GeneOntologyBiologicalProcess	dorsal/ventral pattern formation	GLI1 GLI2 GLI3	7.87e-04	107	35	3	GO:0009953
GeneOntologyBiologicalProcess	dorsal/ventral neural tube patterning	GLI2 GLI3	8.19e-04	25	35	2	GO:0021904
GeneOntologyBiologicalProcess	negative regulation of chondrocyte differentiation	GLI2 GLI3	9.56e-04	27	35	2	GO:0032331
GeneOntologyBiologicalProcess	regulation of stem cell proliferation	SETD1A GLI2 GLI3	1.07e-03	119	35	3	GO:0072091
GeneOntologyBiologicalProcess	epidermal cell differentiation	KRT16 GLI1 GLI2 KRT77	1.32e-03	284	35	4	GO:0009913
GeneOntologyBiologicalProcess	central nervous system projection neuron axonogenesis	GLI2 DCLK1	1.34e-03	32	35	2	GO:0021952
GeneOntologyBiologicalProcess	vesicle fusion to plasma membrane	CACNA1B TRARG1	1.34e-03	32	35	2	GO:0099500
GeneOntologyBiologicalProcess	embryonic digestive tract development	GLI2 GLI3	1.61e-03	35	35	2	GO:0048566
GeneOntologyBiologicalProcess	negative regulation of cartilage development	GLI2 GLI3	1.70e-03	36	35	2	GO:0061037
GeneOntologyCellularComponent	GLI-SUFU complex	GLI1 GLI2 GLI3	1.72e-08	4	35	3	GO:1990788
GeneOntologyCellularComponent	ciliary tip	GLI1 GLI2 GLI3	7.06e-05	48	35	3	GO:0097542
GeneOntologyCellularComponent	nuclear speck	SETD1A ZC3H18 PNISR THRAP3 GLI2 GLI3	7.25e-05	431	35	6	GO:0016607
GeneOntologyCellularComponent	ciliary base	GLI1 GLI2 GLI3	1.12e-04	56	35	3	GO:0097546
GeneOntologyCellularComponent	nuclear body	SETD1A ZC3H18 PNISR THRAP3 GLI2 GLI3 HSPB7	6.38e-04	903	35	7	GO:0016604
MousePheno	abnormal right lung accessory lobe morphology	GLI2 GLI3	4.14e-05	5	29	2	MP:0009571
Domain	SEA	MUC16 MUC3A	2.72e-04	14	33	2	SM00200
Domain	SEA	MUC16 MUC3A	7.48e-04	23	33	2	PS50024
Domain	SEA_dom	MUC16 MUC3A	7.48e-04	23	33	2	IPR000082
Domain	Keratin_I	KRT16 KRT77	2.73e-03	44	33	2	IPR002957
Domain	Intermediate_filament_CS	KRT16 KRT77	5.53e-03	63	33	2	IPR018039
Domain	Filament	KRT16 KRT77	6.97e-03	71	33	2	SM01391
Domain	IF	KRT16 KRT77	7.16e-03	72	33	2	PS00226
Domain	Filament	KRT16 KRT77	7.36e-03	73	33	2	PF00038
Domain	IF	KRT16 KRT77	7.95e-03	76	33	2	IPR001664
Domain	ANK_REPEAT	MUC16 ANK3 PPP1R12A	9.93e-03	253	33	3	PS50088
Domain	ANK_REP_REGION	MUC16 ANK3 PPP1R12A	1.00e-02	254	33	3	PS50297
Pathway	REACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION	GLI1 GLI2 GLI3	1.32e-07	7	23	3	M27501
Pathway	KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY	GLI1 GLI2 GLI3	1.36e-06	14	23	3	M47414
Pathway	BIOCARTA_SHH_PATHWAY	GLI1 GLI2 GLI3	1.70e-06	15	23	3	MM1498
Pathway	WP_HEDGEHOG_SIGNALING_WP47	GLI1 GLI2 GLI3	2.10e-06	16	23	3	M39675
Pathway	BIOCARTA_SHH_PATHWAY	GLI1 GLI2 GLI3	2.10e-06	16	23	3	M11792
Pathway	WP_HEDGEHOG_SIGNALING_PATHWAY	GLI1 GLI2 GLI3	5.73e-06	22	23	3	MM15924
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY	GLI1 GLI2 GLI3	1.35e-05	29	23	3	M47372
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY	GLI1 GLI2 GLI3	1.35e-05	29	23	3	M47377
Pathway	WP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1	GLI1 GLI2 GLI3	1.66e-05	31	23	3	M39522
Pathway	WP_HEDGEHOG_SIGNALING_WP4249	GLI1 GLI2 GLI3	4.49e-05	43	23	3	M39706
Pathway	PID_HEDGEHOG_GLI_PATHWAY	GLI1 GLI2 GLI3	6.25e-05	48	23	3	M219
Pathway	KEGG_BASAL_CELL_CARCINOMA	GLI1 GLI2 GLI3	9.42e-05	55	23	3	M17807
Pathway	KEGG_HEDGEHOG_SIGNALING_PATHWAY	GLI1 GLI2 GLI3	9.94e-05	56	23	3	M1053
Pathway	WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM	GLI1 GLI2 GLI3	1.22e-04	60	23	3	M40048
Pathway	REACTOME_HEDGEHOG_ON_STATE	GLI1 GLI2 GLI3	2.98e-04	81	23	3	MM15225
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC16 MUC3A	3.01e-04	16	23	2	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC16 MUC3A	3.41e-04	17	23	2	M27412
Pathway	REACTOME_HEDGEHOG_ON_STATE	GLI1 GLI2 GLI3	3.55e-04	86	23	3	M27497
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC3A	6.31e-04	23	23	2	M556
Pathway	REACTOME_HEDGEHOG_OFF_STATE	GLI1 GLI2 GLI3	6.38e-04	105	23	3	MM15206
Pathway	REACTOME_HEDGEHOG_OFF_STATE	GLI1 GLI2 GLI3	7.90e-04	113	23	3	M27471
Pathway	REACTOME_DECTIN_2_FAMILY	MUC16 MUC3A	8.08e-04	26	23	2	M27483
Pathway	WP_DOPAMINERGIC_NEUROGENESIS	GLI1 GLI2	1.08e-03	30	23	2	M39580
Pathway	WP_DOPAMINERGIC_NEUROGENESIS	GLI1 GLI2	1.08e-03	30	23	2	MM15831
Pathway	REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT	GLI2 GLI3	1.15e-03	31	23	2	M27805
Pathway	WP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_STAGE_2_OF_3	GLI1 GLI2	1.23e-03	32	23	2	M40041
Pathway	REACTOME_SIGNALING_BY_HEDGEHOG	GLI1 GLI2 GLI3	1.38e-03	137	23	3	MM15182
Pathway	REACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS	MUC16 AHCYL1 MUC3A	1.47e-03	140	23	3	M27484
Pathway	REACTOME_SIGNALING_BY_HEDGEHOG	GLI1 GLI2 GLI3	1.79e-03	150	23	3	M27440
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC16 MUC3A	4.54e-03	62	23	2	M546
Pubmed	Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.	GLI1 GLI2 GLI3	9.34e-10	3	35	3	26010061
Pubmed	A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.	GLI1 GLI2 GLI3	9.34e-10	3	35	3	8387379
Pubmed	Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.	GLI1 GLI2 GLI3	9.34e-10	3	35	3	16571352
Pubmed	Gli family members are differentially expressed during the mitotic phase of spermatogenesis.	GLI1 GLI2 GLI3	9.34e-10	3	35	3	9178901
Pubmed	Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.	GLI1 GLI2 GLI3	9.34e-10	3	35	3	8378770
Pubmed	Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development.	GLI1 GLI2 GLI3	9.34e-10	3	35	3	22178118
Pubmed	Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	9027508
Pubmed	Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	22281533
Pubmed	Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	9006072
Pubmed	Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	27793025
Pubmed	Expression profile of Gli family members and Shh in normal and mutant mouse limb development.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	9438426
Pubmed	Anorectal malformations caused by defects in sonic hedgehog signaling.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	11485934
Pubmed	Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	8150204
Pubmed	Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1.	GLI1 GLI2 GLI3	3.73e-09	4	35	3	10531011
Pubmed	SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	20711444
Pubmed	Functional compensation in Hedgehog signaling during mouse prostate development.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	16707121
Pubmed	Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	19996099
Pubmed	A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	9118802
Pubmed	Evidence for the involvement of the Gli gene family in embryonic mouse lung development.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	9268579
Pubmed	Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	16611981
Pubmed	Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	15315762
Pubmed	Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	10564661
Pubmed	Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	24218555
Pubmed	Gli regulation by the opposing activities of fused and suppressor of fused.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	10806483
Pubmed	p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	26282181
Pubmed	Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	19593328
Pubmed	Gli1 is a target of Sonic hedgehog that induces ventral neural tube development.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	9216996
Pubmed	Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	26120032
Pubmed	Expression pattern of Irx1 and Irx2 during mouse digit development.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	11472848
Pubmed	Expression of the mouse Fgf15 gene is directly initiated by Sonic hedgehog signaling in the diencephalon and midbrain.	GLI1 GLI2 GLI3	9.32e-09	5	35	3	15614767
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	SETD1A GLI1 GLI2 GLI3	1.26e-08	26	35	4	37228654
Pubmed	Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	21549329
Pubmed	Expression of sonic hedgehog signaling molecules in normal, hyperplastic and carcinomatous endometrium.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	19432668
Pubmed	RNF220-mediated ubiquitination promotes aggresomal accumulation and autophagic degradation of cytoplasmic Gli via HDAC6.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	33895473
Pubmed	Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	14681189
Pubmed	Titration of GLI3 repressor activity by sonic hedgehog signaling is critical for maintaining multiple adult neural stem cell and astrocyte functions.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	24174682
Pubmed	Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	17202190
Pubmed	Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	16254602
Pubmed	Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary cilium.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	21209912
Pubmed	Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	19536807
Pubmed	A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	12385751
Pubmed	Phosphorylation of Ci/Gli by Fused Family Kinases Promotes Hedgehog Signaling.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	31279575
Pubmed	Irx1 and Irx2 expression in early lung development.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	11472847
Pubmed	Physical and functional interactions between Zic and Gli proteins.	GLI1 GLI2 GLI3	1.86e-08	6	35	3	11238441
Pubmed	Hedgehog regulates Norrie disease protein to drive neural progenitor self-renewal.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	23201751
Pubmed	FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	19049965
Pubmed	Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	9152005
Pubmed	A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	21653639
Pubmed	Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	14568100
Pubmed	Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	28799057
Pubmed	The GLI-Kruppel family of human genes.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	2850480
Pubmed	Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	9731531
Pubmed	Analysis of the Sonic Hedgehog signaling pathway in normal and abnormal bladder development.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	23308271
Pubmed	Sonic hedgehog regulates discrete populations of astrocytes in the adult mouse forebrain.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	20943901
Pubmed	Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	12435627
Pubmed	Gli3-mediated repression of Hedgehog targets is required for normal mammary development.	GLI1 GLI2 GLI3	3.26e-08	7	35	3	16914490
Pubmed	Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	22265416
Pubmed	Expression of hedgehog signalling components in adult mouse testis.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	16958114
Pubmed	Morphogenesis.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	9988217
Pubmed	The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	28533268
Pubmed	Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	34767969
Pubmed	Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	10529434
Pubmed	Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	12221011
Pubmed	Gli1 is not required for Pdgfralpha expression during mouse embryonic development.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	15811134
Pubmed	GLI transcriptional repression is inert prior to Hedgehog pathway activation.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	35145123
Pubmed	Unique functions of Sonic hedgehog signaling during external genitalia development.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	11684660
Pubmed	Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity.	GLI1 GLI2 GLI3	5.21e-08	8	35	3	10631181
Pubmed	Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	27802276
Pubmed	Distinct expression patterns of Hedgehog signaling components in mouse gustatory system during postnatal tongue development and adult homeostasis.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	38848388
Pubmed	Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	26261006
Pubmed	Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	23249739
Pubmed	Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterning.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	18710724
Pubmed	Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	25083987
Pubmed	Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	17395647
Pubmed	Gli3 null mice display glandular overgrowth of the developing stomach.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	16247775
Pubmed	Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	15315763
Pubmed	Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	10725236
Pubmed	New Insights into Development of Female Reproductive Tract-Hedgehog-Signal Response in Wolffian Tissues Directly Contributes to Uterus Development.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	33530552
Pubmed	The loss of Hh responsiveness by a non-ciliary Gli2 variant.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	25834022
Pubmed	Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	29311969
Pubmed	The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.	GLI1 GLI2 GLI3	7.81e-08	9	35	3	11748155
Pubmed	The Shh signalling pathway in early tooth development.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	10512189
Pubmed	Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	28939119
Pubmed	The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	19549984
Pubmed	Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	16284117
Pubmed	Increasing Sufu gene dosage reveals its unorthodox role in promoting polydactyly and medulloblastoma tumorigenesis.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	38358805
Pubmed	CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	18298960
Pubmed	Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	12812795
Pubmed	Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	15496441
Pubmed	Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	14602680
Pubmed	Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	11943666
Pubmed	Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	9247260
Pubmed	Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	27849569
Pubmed	Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	18083924
Pubmed	Gli1 can rescue the in vivo function of Gli2.	GLI1 GLI2 GLI3	1.11e-07	10	35	3	11748151
Pubmed	Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.	GLI1 GLI2 GLI3	1.53e-07	11	35	3	15668330
Pubmed	Complementary Gli activity mediates early patterning of the mouse visual system.	GLI1 GLI2 GLI3	1.53e-07	11	35	3	16342201
Pubmed	GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis.	GLI1 GLI2 GLI3	1.53e-07	11	35	3	16396903
Pubmed	Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation.	GLI1 GLI2 GLI3	1.53e-07	11	35	3	36252002
Pubmed	Role of Indian hedgehog signaling in palatal osteogenesis.	GLI1 GLI2 GLI3	1.53e-07	11	35	3	21364421
Interaction	NFKBIL1 interactions	NAP1L3 SETD1A AHCYL1 ZC3H18 GPATCH8 KRT77 ZRANB2	1.72e-10	93	34	7	int:NFKBIL1
Interaction	CAMKV interactions	AHCYL1 ZC3H18 GPATCH8 PNISR THRAP3 ZRANB2	4.17e-08	118	34	6	int:CAMKV
Interaction	DHX8 interactions	AHCYL1 ZC3H18 NKTR GPATCH8 PNISR THRAP3 ZRANB2	4.80e-07	292	34	7	int:DHX8
Interaction	SRSF11 interactions	ZC3H18 GPATCH8 PNISR THRAP3 SRRM4 ZRANB2	1.03e-06	203	34	6	int:SRSF11
Interaction	CD2BP2 interactions	AHCYL1 ZC3H18 NKTR GPATCH8 PNISR THRAP3	2.24e-06	232	34	6	int:CD2BP2
Interaction	LUC7L interactions	ZC3H18 NKTR GPATCH8 THRAP3 SRRM4 ZRANB2	2.86e-06	242	34	6	int:LUC7L
Interaction	TRPM8 interactions	TRPM8 ZC3H18 PCNX3	3.52e-06	18	34	3	int:TRPM8
Interaction	SNIP1 interactions	ZC3H18 NKTR GPATCH8 PCNX3 THRAP3 SRRM4 ZRANB2	5.13e-06	417	34	7	int:SNIP1
Interaction	OSBPL10 interactions	ZC3H18 GLI1 ARHGAP21 GLI2	5.72e-06	70	34	4	int:OSBPL10
Interaction	SAP18 interactions	ZC3H18 NKTR GPATCH8 GLI1 THRAP3 GLI3	1.08e-05	305	34	6	int:SAP18
Interaction	SRGAP1 interactions	NKTR GLI1 ARHGAP21 GLI2	1.70e-05	92	34	4	int:SRGAP1
Interaction	SRPK2 interactions	AHCYL1 ZC3H18 NKTR GPATCH8 ANK3 PNISR THRAP3 ZRANB2	1.97e-05	717	34	8	int:SRPK2
Interaction	AKAP17A interactions	AHCYL1 ZC3H18 SRRM4 ZRANB2	2.27e-05	99	34	4	int:AKAP17A
Interaction	CLK3 interactions	AHCYL1 ZC3H18 GPATCH8 SPATS2 THRAP3	3.18e-05	220	34	5	int:CLK3
Interaction	ZIC2 interactions	GLI1 GLI2 GLI3	3.85e-05	39	34	3	int:ZIC2
Interaction	CDC42 interactions	AHCYL1 ZC3H18 ANK3 ADGRL2 VPS51 PCNX3 PNISR THRAP3 ARHGAP21 PPP1R12A	4.40e-05	1323	34	10	int:CDC42
Interaction	CSNK1G2 interactions	AHCYL1 ZC3H18 GPATCH8 ZRANB2	4.67e-05	119	34	4	int:CSNK1G2
Interaction	PLCD3 interactions	SETD1A AHCYL1 PPP1R12A ZRANB2	4.99e-05	121	34	4	int:PLCD3
Interaction	CLK4 interactions	AHCYL1 ZC3H18 SRRM4	5.54e-05	44	34	3	int:CLK4
Interaction	STK36 interactions	GLI1 GLI2 GLI3	5.93e-05	45	34	3	int:STK36
Interaction	RNPS1 interactions	ZC3H18 NKTR GPATCH8 PNISR THRAP3 SRRM4	6.92e-05	425	34	6	int:RNPS1
Interaction	ZFP37 interactions	GLI1 GLI2 GLI3	7.67e-05	49	34	3	int:ZFP37
Interaction	ZNF667 interactions	GLI1 GLI2 GLI3	9.70e-05	53	34	3	int:ZNF667
Interaction	ARRB2 interactions	AHCYL1 NKTR THRAP3 ARHGAP21 PPP1R12A ZRANB2	9.96e-05	454	34	6	int:ARRB2
Interaction	KIF7 interactions	KRT16 GLI1 GLI2 GLI3	1.04e-04	146	34	4	int:KIF7
Interaction	CTCF interactions	SETD1A ZC3H18 GPATCH8 THRAP3 GLI3 ZRANB2	1.08e-04	461	34	6	int:CTCF
Interaction	SYT2 interactions	NAP1L3 SETD1A AHCYL1 GPATCH8	1.15e-04	150	34	4	int:SYT2
Interaction	SRPK1 interactions	AHCYL1 ZC3H18 SPATS2 GLI1 THRAP3 ZRANB2	1.30e-04	477	34	6	int:SRPK1
Interaction	SFN interactions	SETD1A ZC3H18 ARHGEF5 ARHGAP21 KRT77 PPP1R12A ZRANB2	1.31e-04	692	34	7	int:SFN
Interaction	ARHGAP15 interactions	GLI1 ARHGAP21 GLI2	1.34e-04	59	34	3	int:ARHGAP15
Interaction	DDX23 interactions	ZC3H18 NKTR GPATCH8 PNISR THRAP3 ZRANB2	1.35e-04	480	34	6	int:DDX23
Interaction	EPB41L2 interactions	SETD1A ZC3H18 GPATCH8 PPP1R12A ZRANB2	1.36e-04	299	34	5	int:EPB41L2
Interaction	SRSF4 interactions	ZC3H18 NKTR GPATCH8 THRAP3 SRRM4	1.38e-04	300	34	5	int:SRSF4
Interaction	PRICKLE1 interactions	GLI1 ARHGAP21 GLI2	1.41e-04	60	34	3	int:PRICKLE1
Interaction	ZNF287 interactions	GLI1 GLI2 GLI3	1.41e-04	60	34	3	int:ZNF287
Interaction	TNIP2 interactions	NAP1L3 SETD1A ZC3H18 ADGRL2 PNISR THRAP3 ARHGAP21 PPP1R12A	1.46e-04	952	34	8	int:TNIP2
Interaction	LHX5 interactions	GLI1 GLI2	1.51e-04	11	34	2	int:LHX5
Interaction	PRICKLE2 interactions	GLI1 ARHGAP21 GLI2	1.55e-04	62	34	3	int:PRICKLE2
Interaction	HMGN1 interactions	ZC3H18 ANK3 ARHGEF5 ARHGAP21	1.78e-04	168	34	4	int:HMGN1
Interaction	SNRNP70 interactions	AHCYL1 ZC3H18 NKTR GPATCH8 THRAP3 SRRM4 PPP1R12A ZRANB2	1.83e-04	984	34	8	int:SNRNP70
Interaction	AKR7L interactions	SPATS2 PNISR ZRANB2	2.42e-04	72	34	3	int:AKR7L
Interaction	ZNF423 interactions	GLI1 GLI2 GLI3	2.52e-04	73	34	3	int:ZNF423
Interaction	DOK4 interactions	AHCYL1 ANK3 THRAP3	2.62e-04	74	34	3	int:DOK4
Interaction	LUC7L2 interactions	ZC3H18 GPATCH8 THRAP3 SRRM4 ZRANB2	2.94e-04	353	34	5	int:LUC7L2
Interaction	CT45A5 interactions	NAP1L3 SETD1A AHCYL1	3.06e-04	78	34	3	int:CT45A5
Interaction	CLK2 interactions	ZC3H18 NKTR GPATCH8 THRAP3	3.14e-04	195	34	4	int:CLK2
Interaction	SRGAP2 interactions	GLI1 ARHGAP21 GLI2 DCLK1	3.26e-04	197	34	4	int:SRGAP2
Interaction	KCNC1 interactions	ANK3 TRARG1	3.27e-04	16	34	2	int:KCNC1
Interaction	H2BW1 interactions	NAP1L3 ZC3H18	3.27e-04	16	34	2	int:H2BW1
Interaction	ZNF816 interactions	ZC3H18 NKTR	3.27e-04	16	34	2	int:ZNF816
Interaction	PIP4K2A interactions	AHCYL1 GPATCH8 PNISR ZRANB2	4.63e-04	216	34	4	int:PIP4K2A
Interaction	CLK1 interactions	AHCYL1 ZC3H18 THRAP3 SRRM4	4.87e-04	219	34	4	int:CLK1
Interaction	ATG16L1 interactions	NKTR GPATCH8 ANK3 VPS51 PNISR GLI2 PPP1R12A ZRANB2	5.61e-04	1161	34	8	int:ATG16L1
Interaction	PIP4K2B interactions	AHCYL1 HSPB7 ZRANB2	5.63e-04	96	34	3	int:PIP4K2B
Interaction	NUAK1 interactions	ZC3H18 KRT77 PPP1R12A	5.63e-04	96	34	3	int:NUAK1
Interaction	VAV1 interactions	GLI1 ARHGAP21 GLI2 PPP1R12A	5.67e-04	228	34	4	int:VAV1
Interaction	ZNF543 interactions	ZC3H18 NKTR	5.69e-04	21	34	2	int:ZNF543
Interaction	CHN2 interactions	GLI1 ARHGAP21 GLI2	5.80e-04	97	34	3	int:CHN2
Interaction	LUZP4 interactions	THRAP3 SRRM4 PPP1R12A	6.16e-04	99	34	3	int:LUZP4
Interaction	ZFP62 interactions	GLI1 GLI2 GLI3	6.16e-04	99	34	3	int:ZFP62
Interaction	GLI2 interactions	GLI1 GLI2 GLI3	6.16e-04	99	34	3	int:GLI2
Interaction	RNF8 interactions	KRT16 PNISR THRAP3 KRT77 ZRANB2	6.56e-04	421	34	5	int:RNF8
Interaction	TYMS interactions	AHCYL1 PROSER2 ZRANB2	6.91e-04	103	34	3	int:TYMS
Interaction	PCNT interactions	SETD1A AHCYL1 PNISR ARHGAP21	6.98e-04	241	34	4	int:PCNT
Interaction	SUFU interactions	GLI1 GLI2 GLI3	7.52e-04	106	34	3	int:SUFU
Interaction	HDAC6 interactions	SETD1A KRT16 GLI1 GLI2 GLI3 KRT77 PPP1R12A	7.80e-04	929	34	7	int:HDAC6
Interaction	DHX40 interactions	ZC3H18 GPATCH8 PNISR THRAP3	7.88e-04	249	34	4	int:DHX40
Interaction	ARL6IP4 interactions	ZC3H18 SRRM4 ZRANB2	8.15e-04	109	34	3	int:ARL6IP4
Interaction	CHD4 interactions	SETD1A ZC3H18 GPATCH8 KRT16 THRAP3 KRT77 PPP1R12A	8.26e-04	938	34	7	int:CHD4
Interaction	ZFPL1 interactions	AHCYL1 ANK3 ADGRL2 VPS51 ARHGAP21	8.68e-04	448	34	5	int:ZFPL1
Interaction	STX6 interactions	AHCYL1 ANK3 ADGRL2 VPS51 ARHGAP21	8.68e-04	448	34	5	int:STX6
Interaction	FBXL7 interactions	AHCYL1 ZRANB2	8.75e-04	26	34	2	int:FBXL7
Interaction	YWHAG interactions	NKTR PROSER2 THRAP3 ARHGEF5 ARHGAP21 DCLK1 KRT77 PPP1R12A	9.03e-04	1248	34	8	int:YWHAG
Interaction	RAD18 interactions	SETD1A ZC3H18 PNISR THRAP3 ZRANB2	9.49e-04	457	34	5	int:RAD18
Interaction	DIRAS3 interactions	ANK3 ADGRL2 PCNX3 ARHGAP21	9.53e-04	262	34	4	int:DIRAS3
Interaction	ZIC1 interactions	GLI1 GLI2 GLI3	9.76e-04	116	34	3	int:ZIC1
Interaction	TTLL12 interactions	AHCYL1 PPP1R12A ZRANB2	1.00e-03	117	34	3	int:TTLL12
Interaction	ARHGAP26 interactions	GLI1 ARHGAP21 GLI2	1.08e-03	120	34	3	int:ARHGAP26
Interaction	SCN1A interactions	CACNA1B ANK3	1.09e-03	29	34	2	int:SCN1A
Interaction	PDE6B interactions	GLI1 GLI2	1.09e-03	29	34	2	int:PDE6B
Interaction	EPB41L3 interactions	SETD1A ZC3H18 GPATCH8 ZRANB2	1.09e-03	272	34	4	int:EPB41L3
Interaction	MECP2 interactions	ZC3H18 NKTR GPATCH8 KRT16 PNISR THRAP3 ARHGEF5 ZRANB2	1.10e-03	1287	34	8	int:MECP2
Interaction	FBXW11 interactions	AHCYL1 ZC3H18 THRAP3 GLI2 GLI3	1.11e-03	473	34	5	int:FBXW11
Interaction	RND3 interactions	AHCYL1 ANK3 ADGRL2 ARHGAP21	1.11e-03	273	34	4	int:RND3
Interaction	LYN interactions	AHCYL1 ANK3 ADGRL2 THRAP3 ARHGEF5 ARHGAP21	1.16e-03	720	34	6	int:LYN
Interaction	SNRPA interactions	AHCYL1 ZC3H18 NKTR THRAP3 ARHGEF5	1.20e-03	482	34	5	int:SNRPA
Interaction	NEK2 interactions	SETD1A THRAP3 PPP1R12A	1.27e-03	127	34	3	int:NEK2
Interaction	LGALS3BP interactions	ZC3H18 ARHGAP21 GLI2 GLI3	1.32e-03	286	34	4	int:LGALS3BP
Interaction	MYNN interactions	GLI1 GLI2	1.33e-03	32	34	2	int:MYNN
Interaction	PLD1 interactions	AHCYL1 ZC3H18 ZRANB2	1.36e-03	130	34	3	int:PLD1
Interaction	EPS8 interactions	PROSER2 ARHGAP21 GLI2	1.54e-03	136	34	3	int:EPS8
Interaction	CIBAR1 interactions	KRT16 THRAP3 KRT77	1.58e-03	137	34	3	int:CIBAR1
Interaction	SOST interactions	AHCYL1 PPP1R12A	1.59e-03	35	34	2	int:SOST
Interaction	PNN interactions	ZC3H18 NKTR PNISR THRAP3	1.61e-03	302	34	4	int:PNN
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	SPATS2 GLI1 KRT77	4.08e-03	423	35	3	chr12q13
GeneFamily	CD molecules\|Mucins	MUC16 MUC3A	3.79e-04	21	25	2	648
Coexpression	ULE_SPLICING_VIA_NOVA2	CACNA1B ANK3 ARHGAP21	2.59e-05	43	35	3	MM666
Coexpression	ULE_SPLICING_VIA_NOVA2	CACNA1B ANK3 ARHGAP21	2.59e-05	43	35	3	M1551
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ANK3 ADGRL2 DCLK1 SRRM4	4.58e-07	198	35	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1B ANK3 ADGRL2 DCLK1 SRRM4	4.81e-07	200	35	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AHCYL1 GLI1 GLI2 GLI3	2.44e-06	121	35	4	8334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AHCYL1 GLI1 GLI2 GLI3	2.44e-06	121	35	4	4b33eeed7b70da120133b14d42c104d2461d52dc
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AHCYL1 GLI1 GLI2 GLI3	2.44e-06	121	35	4	a33e4ae0b0efb702db1b646ac0486e3b6ce48457
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	7.22e-06	159	35	4	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	7.22e-06	159	35	4	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAP1L3 C7 GLI2 DCLK1	8.97e-06	168	35	4	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAP1L3 C7 GLI2 DCLK1	9.62e-06	171	35	4	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.03e-05	174	35	4	9c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.03e-05	174	35	4	bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 NKTR ANK3 ARHGAP21	1.15e-05	179	35	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.28e-05	184	35	4	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ANK3 GLI2 DCLK1 GLI3	1.34e-05	186	35	4	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	NAP1L3 C7 GLI1 GLI2	1.40e-05	188	35	4	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.43e-05	189	35	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.43e-05	189	35	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	NKTR ANK3 PNISR ZRANB2	1.43e-05	189	35	4	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.46e-05	190	35	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.49e-05	191	35	4	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C7 GLI1 GLI2 DCLK1	1.49e-05	191	35	4	24dc77ee8de01b42559f92721655f4281b114e17
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	ANK3 GLI2 DCLK1 GLI3	1.49e-05	191	35	4	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK3 GLI1 GLI2 HSPB7	1.49e-05	191	35	4	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.49e-05	191	35	4	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.52e-05	192	35	4	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.52e-05	192	35	4	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.52e-05	192	35	4	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.52e-05	192	35	4	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.52e-05	192	35	4	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.55e-05	193	35	4	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C7 GLI1 DCLK1 GLI3	1.55e-05	193	35	4	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	C7 GLI2 DCLK1 GLI3	1.58e-05	194	35	4	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.58e-05	194	35	4	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.58e-05	194	35	4	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	C7 ADGRL2 GLI2 GLI3	1.58e-05	194	35	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.61e-05	195	35	4	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	NKTR ANK3 PNISR ZRANB2	1.61e-05	195	35	4	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	C7 ADGRL2 GLI2 GLI3	1.61e-05	195	35	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC29A3 C7 ADGRL2 PNISR	1.61e-05	195	35	4	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ADGRL2 DCLK1 SRRM4	1.65e-05	196	35	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	C7 GLI2 DCLK1 GLI3	1.68e-05	197	35	4	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NKTR ANK3 PNISR ZRANB2	1.68e-05	197	35	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1 GLI3	1.68e-05	197	35	4	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	C7 GLI2 DCLK1 GLI3	1.68e-05	197	35	4	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MUC16 MUC3A GLI2 HSPB7	1.71e-05	198	35	4	5cfd1c030c0940136a397b5a4b5d6ecbaecf72eb
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ADGRL2 DCLK1 SRRM4	1.71e-05	198	35	4	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MUC16 MUC3A GLI2 HSPB7	1.71e-05	198	35	4	35edf6d5bedc2181fbdd56f43e458bc39f4eca16
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MUC16 MUC3A GLI2 HSPB7	1.71e-05	198	35	4	ff6d9455ebfe965cc6f48197172c0ebd3bddde81
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ADGRL2 DCLK1 SRRM4	1.71e-05	198	35	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MUC16 MUC3A GLI2 HSPB7	1.71e-05	198	35	4	5375a2895cf995f0db4a61861093f01794707901
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.71e-05	198	35	4	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B ADGRL2 DCLK1 SRRM4	1.71e-05	198	35	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NKTR ANK3 PNISR ZRANB2	1.75e-05	199	35	4	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	C7 GLI2 DCLK1 GLI3	1.75e-05	199	35	4	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NAP1L3 ANK3 DCLK1 SRRM4	1.75e-05	199	35	4	5de2a32bc2e9c752eb19a013b1807949153728fc
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NKTR C7 ADGRL2 PNISR	1.75e-05	199	35	4	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANK3 GLI2 DCLK1 GLI3	1.78e-05	200	35	4	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ANK3 GLI2 DCLK1 GLI3	1.78e-05	200	35	4	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AHCYL1 GLI1 GLI3	1.11e-04	119	35	3	79342c491a214c870ff6215da613db4a28c9d587
ToppCell	Hippocampus-Macroglia-ASTROCYTE\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AHCYL1 GLI1 GLI3	1.11e-04	119	35	3	36857095d4e4cc6428d13bf7de04daec1f4cde1e
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	C7 TRARG1 GLI2	1.28e-04	125	35	3	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	NKTR PNISR ZRANB2	2.07e-04	147	35	3	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	NKTR ANK3 PNISR	2.24e-04	151	35	3	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAP1L3 TRARG1 GLI2	2.61e-04	159	35	3	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	POM121L2 C7 GLI2	2.61e-04	159	35	3	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	NKTR ANK3 PNISR	2.76e-04	162	35	3	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPATS2 ANK3 ADGRL2	2.76e-04	162	35	3	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MUC16 KRT16 ARHGEF5	2.76e-04	162	35	3	112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCell	343B-Fibroblasts-Fibroblast-D-\|343B / Donor, Lineage, Cell class and subclass (all cells)	NAP1L3 C7 GLI1	2.81e-04	163	35	3	8d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCell	343B-Fibroblasts-Fibroblast-D\|343B / Donor, Lineage, Cell class and subclass (all cells)	NAP1L3 C7 GLI1	2.81e-04	163	35	3	acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPATS2 ANK3 ADGRL2	2.86e-04	164	35	3	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ANK3 ARHGAP21 HSPB7	2.91e-04	165	35	3	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C7 ANK3 DCLK1	3.12e-04	169	35	3	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	GLI1 GLI2 HSPB7	3.23e-04	171	35	3	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ANK3 DCLK1 HSPB7	3.23e-04	171	35	3	e59afa0a773dca3b9c208d17510ea55703b42598
ToppCell	AT1-AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	KRT16 DCLK1 HSPB7	3.23e-04	171	35	3	0b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AHCYL1 ANK3 PNISR	3.34e-04	173	35	3	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 KRT16 MUC3A	3.40e-04	174	35	3	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 ANK3 GLI2	3.40e-04	174	35	3	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROSER2 PCNX3 GLI1	3.40e-04	174	35	3	c58328c2f262506a4518f49f148e29874faf9171
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	CACNA1B DCLK1 SRRM4	3.45e-04	175	35	3	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	CACNA1B DCLK1 SRRM4	3.45e-04	175	35	3	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1	3.45e-04	175	35	3	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	C7 GLI2 DCLK1	3.51e-04	176	35	3	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	C7 GLI2 DCLK1	3.51e-04	176	35	3	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NAP1L3 C7 GLI2	3.57e-04	177	35	3	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NAP1L3 C7 GLI2	3.57e-04	177	35	3	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRARG1 PPP1R12A HSPB7	3.57e-04	177	35	3	928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C7 KRT16 ANK3	3.57e-04	177	35	3	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETD1A TRARG1 GLI1	3.69e-04	179	35	3	b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C7 DCLK1 GLI3	3.69e-04	179	35	3	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	POM121L2 ANK3 ADGRL2	3.69e-04	179	35	3	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1B DCLK1 SRRM4	3.75e-04	180	35	3	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C7 ADGRL2 SRRM4	3.81e-04	181	35	3	e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	NAP1L3 DCLK1 HSPB7	3.81e-04	181	35	3	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLI1 GLI2 GLI3	3.94e-04	183	35	3	99bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRARG1 GLI1 HSPB7	3.94e-04	183	35	3	8de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLI1 DCLK1 GLI3	4.00e-04	184	35	3	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C7 GLI2 DCLK1	4.00e-04	184	35	3	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C7 GLI1 SRRM4	4.00e-04	184	35	3	fe4d3def3da4ffdea5ae6bb059f5397efd58fef3
Drug	AC1NDK86	GLI1 GLI3 PPP1R12A	6.59e-06	24	35	3	CID004627205
Drug	guaifenesin	C7 KRT16 GLI1 KRT77	9.51e-06	87	35	4	CID000003516
Drug	radicicol; Down 200; 0.1uM; MCF7; HG-U133A	SLC24A1 PNISR GLI2 GLI3 HSPB7	1.18e-05	196	35	5	325_DN
Drug	AC1L1GT5	KRT16 ADGRL2 GLI1 PPP1R12A	1.35e-05	95	35	4	CID000003829
Drug	JK184	GLI1 GLI2	1.37e-05	4	35	2	ctd:C525593
Drug	SANT-1 compound	GLI1 GLI2	1.37e-05	4	35	2	ctd:C468919
Drug	1,4-diaminocyclohexane	GLI1 GLI2	1.37e-05	4	35	2	ctd:C088969
Drug	LDE225	GLI1 GLI2	2.29e-05	5	35	2	ctd:C561435
Drug	cyclopamine	GLI1 GLI2 HSPB7	4.83e-05	46	35	3	ctd:C000541
Disease	primary bacterial infectious disease (implicated_via_orthology)	GLI1 GLI2 GLI3	1.17e-07	9	34	3	DOID:0050338 (implicated_via_orthology)
Disease	Gastrointestinal Stromal Sarcoma	GLI1 GLI2 GLI3	2.19e-05	47	34	3	C3179349
Disease	Gastrointestinal Stromal Tumors	GLI1 GLI2 GLI3	2.64e-05	50	34	3	C0238198
Disease	Holoprosencephaly	GLI2 PPP1R12A	1.73e-04	17	34	2	C0079541
Disease	pre-malignant neoplasm (biomarker_via_orthology)	GLI1 GLI3	1.73e-04	17	34	2	DOID:0060071 (biomarker_via_orthology)
Disease	response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema	POM121L2 DCLK1	4.12e-04	26	34	2	EFO_0005325, EFO_0005532, EFO_0010735
Disease	prostate carcinoma, breast carcinoma, ovarian carcinoma	ARHGEF5 HSPB7	4.44e-04	27	34	2	EFO_0000305, EFO_0001075, EFO_0001663
Disease	aseptic loosening, revision of total knee arthroplasty	TRPM8 ANK3	1.08e-03	42	34	2	EFO_0010725, EFO_0020972
Disease	Acute Promyelocytic Leukemia	GLI1 GLI2	1.29e-03	46	34	2	C0023487
Disease	multiple sclerosis (is_marker_for)	CACNA1B GLI1	1.46e-03	49	34	2	DOID:2377 (is_marker_for)
Disease	Peripheral Nervous System Diseases	CACNA1B GLI1	1.78e-03	54	34	2	C4721453
Disease	heart rate	PROSER2 ARHGAP21 DCLK1	2.20e-03	225	34	3	EFO_0004326
Disease	cholangiocarcinoma (is_marker_for)	MUC16 MUC3A	2.48e-03	64	34	2	DOID:4947 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ATARSTESFTSTSRS	ARHGEF5	901	Q12774
SVKASTTRTSARYSS	ADGRL2	1116	O95490
TNSGRSSRTSYVSSL	CACNA1B	2286	Q00975
SSRTSYVSSLTSQSH	CACNA1B	2291	Q00975
STLASESVTSRTSYN	MUC16	12011	Q8WXI7
RRDSSASTISSAYLS	GLI3	846	P10071
ASTISSAYLSSRRSS	GLI3	851	P10071
TSSRTLTYYTSTSSR	SLC24A1	146	O60721
STSYTKIASSSRRST	DCLK1	281	O15075
SSHRSSRRSYSSSSD	GPATCH8	861	Q9UKJ3
LRSQRRYSTDSSSST	PCNX3	436	Q9H6A9
TSALTDSTTRTTYST	MUC3A	1846	Q02505
REVFTSSSSSSSRQT	KRT16	441	P08779
RRSSSSSSISSAYTV	GLI1	541	P08151
SSSISSAYTVSRRSS	GLI1	546	P08151
RDSSTSTVSSAYTVS	GLI2	806	P10070
STVSSAYTVSRRSSG	GLI2	811	P10070
SSTFRAERSFHSSSS	HSPB7	6	Q9UBY9
RSSSSSSRSYTSHTN	C7	226	P10643
SASLRSFSSDRSYTL	ANK3	911	Q12955
HSSNSTYRTTSSSLR	SLC29A3	11	Q9BZD2
SVSYSHSRSRSRSST	NKTR	1331	P30414
RSLSRSISQSSTDSY	AHCYL1	61	O43865
SLESRSSSSRSRSFT	PROSER2	31	Q86WR7
SSSSSGSTSSRSRLY	NAP1L3	61	Q99457
RRHFSASSASTTAST	SETD1A	311	O15047
YSRISVTAAASSISS	POM121L2	551	Q96KW2
SDSSKRTFSVYSSSR	VPS51	641	Q9UID3
NSYSTRSRCSSVTSV	SPATS2	376	Q86XZ4
RSRSSSSSSQSSHSY	THRAP3	776	Q9Y2W1
RSSSYASTRSSSHSS	SRRM4	391	A7MD48
SRSRSQSRSYSSADS	SRRM4	591	A7MD48
SSSPRKRSYSSSSSS	ZRANB2	266	O95218
YSSSSGSSRTSSRSS	PNISR	536	Q8TF01
ASSRRASSIATTSYA	TRARG1	81	Q8IXB3
TRTLYSSASRSTDLS	TRPM8	21	Q7Z2W7
SSATYLTSLDSSRLS	ARHGAP21	1591	Q5T5U3
ASNSSRSSSRSSSYS	ZC3H18	551	Q86VM9
FSSMSRRVYSTSSSA	KRT77	11	Q7Z794
NRDSSSLRTSSSYTR	PPP1R12A	516	O14974