Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	SREBP-SCAP complex retention in endoplasmic reticulum	INSIG1 INSIG2	2.19e-05	2	97	2	GO:0036316
GeneOntologyBiologicalProcess	SREBP signaling pathway	INSIG1 SREBF1 INSIG2	5.40e-05	16	97	3	GO:0032933
GeneOntologyBiologicalProcess	cellular response to sterol depletion	INSIG1 SREBF1 INSIG2	6.54e-05	17	97	3	GO:0071501
GeneOntologyBiologicalProcess	negative regulation of SREBP signaling pathway	INSIG1 INSIG2	6.55e-05	3	97	2	GO:2000639
GeneOntologyBiologicalProcess	response to sterol depletion	INSIG1 SREBF1 INSIG2	9.25e-05	19	97	3	GO:0006991
GeneOntologyBiologicalProcess	morphogenesis of an endothelium	DLL4 ADAMTS12 BSG	1.26e-04	21	97	3	GO:0003159
GeneOntologyBiologicalProcess	endothelial tube morphogenesis	DLL4 ADAMTS12 BSG	1.26e-04	21	97	3	GO:0061154
GeneOntologyBiologicalProcess	regulation of steroid biosynthetic process	INSIG1 SREBF1 DHCR7 INSIG2 FGFR4	1.44e-04	106	97	5	GO:0050810
GeneOntologyBiologicalProcess	monocarboxylic acid biosynthetic process	INSIG1 SREBF1 FASN INSIG2 ALOXE3 FGFR4 WDTC1	2.28e-04	260	97	7	GO:0072330
GeneOntologyBiologicalProcess	cholesterol biosynthetic process	INSIG1 SREBF1 DHCR7 INSIG2	2.50e-04	65	97	4	GO:0006695
GeneOntologyBiologicalProcess	secondary alcohol biosynthetic process	INSIG1 SREBF1 DHCR7 INSIG2	2.50e-04	65	97	4	GO:1902653
GeneOntologyCellularComponent	SREBP-SCAP-Insig complex	INSIG1 INSIG2	6.24e-05	3	96	2	GO:0032937
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	ATG101 INSIG1 B3GALNT2 SREBF1 SYNE4 LPIN3 LMAN1L ZDHHC20 KCNA2 BSG DHCR7 INSIG2 UBAC2 SELENOI GRIN3A GRIN3B CREB3	1.04e-04	1327	96	17	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum membrane	ATG101 INSIG1 B3GALNT2 SREBF1 LPIN3 LMAN1L ZDHHC20 KCNA2 BSG DHCR7 INSIG2 UBAC2 SELENOI GRIN3A GRIN3B CREB3	2.53e-04	1293	96	16	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	ATG101 INSIG1 B3GALNT2 SREBF1 LPIN3 LMAN1L ZDHHC20 KCNA2 BSG DHCR7 INSIG2 UBAC2 SELENOI GRIN3A GRIN3B CREB3	2.67e-04	1299	96	16	GO:0098827
GeneOntologyCellularComponent	NMDA selective glutamate receptor complex	GRIN3A GRIN3B	7.36e-04	9	96	2	GO:0017146
Domain	K_chnl_volt-dep_Kv1	KCNA2 KCNA5 KCNA6	7.94e-06	8	99	3	IPR003972
Domain	IG_LIKE	SLAMF8 CILP AXL KIRREL2 CCDC141 FCRL6 IGHD BSG NCAN FGFR4 MYBPHL IGSF23	1.11e-05	491	99	12	PS50835
Domain	Ig-like_dom	SLAMF8 CILP AXL KIRREL2 CCDC141 FCRL6 IGHD BSG NCAN FGFR4 MYBPHL IGSF23	1.41e-05	503	99	12	IPR007110
Domain	Ig-like_fold	SLAMF8 EPOR CILP AXL KIRREL2 CCDC141 FCRL6 IGHD BSG NCAN FGFR4 MYBPHL IL2RB IGSF23	2.08e-05	706	99	14	IPR013783
Domain	INSIG_fam	INSIG1 INSIG2	2.78e-05	2	99	2	IPR025929
Domain	INSIG	INSIG1 INSIG2	2.78e-05	2	99	2	PF07281
Domain	INSIG-1	INSIG1 INSIG2	2.78e-05	2	99	2	IPR009904
Domain	-	EPOR CILP AXL KIRREL2 CCDC141 FCRL6 BSG NCAN FGFR4 MYBPHL IL2RB IGSF23	1.99e-04	663	99	12	2.60.40.10
Domain	TSP_1	CILP ADAMTS1 SSPOP ADAMTS12	3.48e-04	63	99	4	PF00090
Domain	K_chnl_volt-dep_Kv	KCNA2 KCNA5 KCNA6	3.85e-04	27	99	3	IPR003968
Domain	TSP1	CILP ADAMTS1 SSPOP ADAMTS12	3.92e-04	65	99	4	SM00209
Domain	TSP1_rpt	CILP ADAMTS1 SSPOP ADAMTS12	3.92e-04	65	99	4	IPR000884
Domain	TSP1	CILP ADAMTS1 SSPOP ADAMTS12	3.92e-04	65	99	4	PS50092
Domain	Ig_I-set	CILP AXL KIRREL2 BSG FGFR4 MYBPHL	5.24e-04	190	99	6	IPR013098
Domain	I-set	CILP AXL KIRREL2 BSG FGFR4 MYBPHL	5.24e-04	190	99	6	PF07679
Domain	VG_K_chnl	KCNA2 KCNA5 KCNA6	7.02e-04	33	99	3	IPR028325
Pathway	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	INSIG1 SREBF1 FASN DHCR7 INSIG2	9.22e-06	55	73	5	M27001
Pubmed	Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?	INSIG1 SREBF1 INSIG2	2.51e-07	5	103	3	18195716
Pubmed	Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.	INSIG1 SREBF1 INSIG2	2.51e-07	5	103	3	16100574
Pubmed	Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.	INSIG1 SREBF1 INSIG2	2.51e-07	5	103	3	12242332
Pubmed	The gene-gene interaction of INSIG-SCAP-SREBP pathway on the risk of obesity in Chinese children.	INSIG1 SREBF1 INSIG2	2.51e-07	5	103	3	25028659
Pubmed	Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.	KCNA2 KCNA5 KCNA6	5.01e-07	6	103	3	9286706
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RBBP4 AXL B3GALNT2 SREBF1 RNF213 OLFML2A FAT1 NF1 BSG DHCR7 TMEM131L UBAC2 FUCA2 FGFR4 SELENOI	2.58e-06	1201	103	15	35696571
Pubmed	Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.	KCNA2 KCNA5 KCNA6	2.98e-06	10	103	3	1383027
Pubmed	CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.	AXL CLEC7A BSG PIK3R2 IL2RB	6.29e-06	87	103	5	29991678
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	CILP DLL4 CLEC7A FAM131A KIRREL2 SNAP47 ARMCX3 ADAMTS12 LMAN1L OLFML2A BSG FUCA2 PCSK4	7.10e-06	985	103	13	12975309
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	EFL1 ATP6V0B DLL4 SLC22A23 INSIG1 SREBF1 PFAS LMAN1L FASN NF1 BSG PIK3R2 TMEM131L SELENOI SOWAHB	8.56e-06	1327	103	15	32694731
Pubmed	Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport.	SREBF1 FASN	8.69e-06	2	103	2	12213084
Pubmed	Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.	INSIG1 INSIG2	8.69e-06	2	103	2	20090767
Pubmed	Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.	INSIG1 INSIG2	8.69e-06	2	103	2	19638338
Pubmed	Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.	INSIG1 INSIG2	8.69e-06	2	103	2	16955138
Pubmed	Sterol regulatory element binding protein-1 (SREBP1) activation in motor neurons in excitotoxicity and amyotrophic lateral sclerosis (ALS): Indip, a potential therapeutic peptide.	INSIG1 SREBF1	8.69e-06	2	103	2	21871872
Pubmed	Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.	GRIN3A GRIN3B	8.69e-06	2	103	2	11735224
Pubmed	Silibinin attenuates adipogenesis in 3T3-L1 preadipocytes through a potential upregulation of the insig pathway.	INSIG1 INSIG2	8.69e-06	2	103	2	19360322
Pubmed	The INSIG1 gene, not the INSIG2 gene, associated with coronary heart disease: tagSNPs and haplotype-based association study. The Beijing Atherosclerosis Study.	INSIG1 INSIG2	8.69e-06	2	103	2	18989534
Pubmed	Voltage-gated K+ channels in rat small cerebral arteries: molecular identity of the functional channels.	KCNA2 KCNA5	8.69e-06	2	103	2	12815189
Pubmed	CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.	ADAMTS1 BSG	8.69e-06	2	103	2	26675551
Pubmed	Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.	INSIG1 INSIG2	8.69e-06	2	103	2	19617589
Pubmed	p85β regulates autophagic degradation of AXL to activate oncogenic signaling.	AXL PIK3R2	8.69e-06	2	103	2	32385243
Pubmed	Gene-gene interactions of the INSIG1 and INSIG2 in metabolic syndrome in schizophrenic patients treated with atypical antipsychotics.	INSIG1 INSIG2	8.69e-06	2	103	2	20877301
Pubmed	Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis.	INSIG1 INSIG2	8.69e-06	2	103	2	12624180
Pubmed	SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer.	SREBF1 FASN	8.69e-06	2	103	2	33665967
Pubmed	Genetic variation in N-methyl-D-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease.	GRIN3A GRIN3B	8.69e-06	2	103	2	20016182
Pubmed	Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2.	SREBF1 FASN	8.69e-06	2	103	2	18420801
Pubmed	Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals.	SREBF1 FASN	8.69e-06	2	103	2	12897158
Pubmed	Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.	SREBF1 FASN	8.69e-06	2	103	2	18281474
Pubmed	Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells.	SREBF1 FASN	8.69e-06	2	103	2	22786746
Pubmed	Assisted reproductive technologies impair the expression and methylation of insulin-induced gene 1 and sterol regulatory element-binding factor 1 in the fetus and placenta.	INSIG1 SREBF1	8.69e-06	2	103	2	24484994
Pubmed	Sterol regulatory element-binding protein-1/fatty acid synthase involvement in proliferation inhibition and apoptosis promotion induced by progesterone in endometrial cancer.	SREBF1 FASN	8.69e-06	2	103	2	24105476
Pubmed	Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine.	INSIG1 INSIG2	8.69e-06	2	103	2	24337570
Pubmed	SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.	INSIG1 SREBF1 FASN	2.36e-05	19	103	3	26685326
Pubmed	CRTC2 modulates hepatic SREBP1c cleavage by controlling Insig2a expression during fasting.	SREBF1 INSIG2	2.60e-05	3	103	2	29679236
Pubmed	Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2.	INSIG1 INSIG2	2.60e-05	3	103	2	31953408
Pubmed	B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN.	SREBF1 FASN	2.60e-05	3	103	2	27939887
Pubmed	Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13.	KCNA5 KCNA6	2.60e-05	3	103	2	8821794
Pubmed	Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis.	INSIG1 INSIG2	2.60e-05	3	103	2	34298014
Pubmed	Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD.	SREBF1 FASN	2.60e-05	3	103	2	28027934
Pubmed	Metformin targets Clusterin to control lipogenesis and inhibit the growth of bladder cancer cells through SREBP-1c/FASN axis.	SREBF1 FASN	2.60e-05	3	103	2	33649289
Pubmed	Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.	INSIG1 INSIG2	2.60e-05	3	103	2	12482938
Pubmed	Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN).	SREBF1 FASN	2.60e-05	3	103	2	18682402
Pubmed	Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinoma.	SREBF1 FASN	2.60e-05	3	103	2	30914315
Pubmed	Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII.	KCNA2 KCNA5	2.60e-05	3	103	2	24682423
Pubmed	Genetic variation in genes of the fatty acid synthesis pathway and breast cancer risk.	SREBF1 FASN	2.60e-05	3	103	2	19252981
Pubmed	FAS/SREBP-1c contributes to colorectal carcinogenesis through calcium signaling pathway and cAMP signaling pathway.	SREBF1 FASN	2.60e-05	3	103	2	38143182
Pubmed	Cloning, sequence and chromosomal localization of MK6, a murine potassium channel gene.	KCNA2 KCNA6	2.60e-05	3	103	2	1285906
Pubmed	Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation.	INSIG1 INSIG2	2.60e-05	3	103	2	24806461
Pubmed	Clinical spectrum of voltage-gated potassium channel autoimmunity.	KCNA2 KCNA6	2.60e-05	3	103	2	18474843
Pubmed	Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons.	KCNA2 KCNA6	2.60e-05	3	103	2	17634333
Pubmed	Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice.	INSIG1 SREBF1	2.60e-05	3	103	2	18627005
Pubmed	Proteasomal degradation of ubiquitinated Insig proteins is determined by serine residues flanking ubiquitinated lysines.	INSIG1 INSIG2	2.60e-05	3	103	2	16549805
Pubmed	Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth.	INSIG1 SREBF1	2.60e-05	3	103	2	26555173
Pubmed	PPARα-dependent Insig2a overexpression inhibits SREBP-1c processing during fasting.	SREBF1 INSIG2	2.60e-05	3	103	2	28855656
Pubmed	Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c.	SREBF1 FASN	2.60e-05	3	103	2	12531699
Pubmed	Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.	INSIG1 SREBF1	2.60e-05	3	103	2	15085196
Pubmed	Cholesterol metabolism plays a crucial role in the regulation of autophagy for cell differentiation of granular convoluted tubules in male mouse submandibular glands.	INSIG1 INSIG2	2.60e-05	3	103	2	31558435
Pubmed	Peroxisome deficiency causes a complex phenotype because of hepatic SREBP/Insig dysregulation associated with endoplasmic reticulum stress.	SREBF1 INSIG2	5.19e-05	4	103	2	19110480
Pubmed	Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.	INSIG1 INSIG2	5.19e-05	4	103	2	19740467
Pubmed	Inhibition of DNA-dependent protein kinase reduced palmitate and oleate-induced lipid accumulation in HepG2 cells.	SREBF1 FASN	5.19e-05	4	103	2	23184344
Pubmed	Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs.	INSIG1 INSIG2	5.19e-05	4	103	2	12842885
Pubmed	Ligand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemia.	EPOR PIK3R2	5.19e-05	4	103	2	19336760
Pubmed	Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis.	INSIG1 INSIG2	5.19e-05	4	103	2	16606821
Pubmed	CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.	SREBF1 INSIG2	5.19e-05	4	103	2	34974159
Pubmed	γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6.	SREBF1 FASN	5.19e-05	4	103	2	23727646
Pubmed	NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons.	GRIN3A GRIN3B	5.19e-05	4	103	2	15813953
Pubmed	HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway.	SREBF1 FASN	5.19e-05	4	103	2	25855506
Pubmed	Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter.	SREBF1 FASN	5.19e-05	4	103	2	22331133
Pubmed	Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.	INSIG1 INSIG2	5.19e-05	4	103	2	15899885
Pubmed	LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance.	EPOR DLL4	5.19e-05	4	103	2	23134786
Pubmed	Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.	INSIG1 SREBF1	5.19e-05	4	103	2	12202038
Pubmed	The SDF-1alpha/CXCR4 axis induces the expression of fatty acid synthase via sterol regulatory element-binding protein-1 activation in cancer cells.	SREBF1 FASN	5.19e-05	4	103	2	20067991
Pubmed	Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels.	KCNA2 KCNA5	5.19e-05	4	103	2	32186932
Pubmed	Essential role in vivo of upstream stimulatory factors for a normal dietary response of the fatty acid synthase gene in the liver.	SREBF1 FASN	5.19e-05	4	103	2	9890958
Pubmed	Sp1 coordinately regulates de novo lipogenesis and proliferation in cancer cells.	SREBF1 FASN	5.19e-05	4	103	2	19621387
Pubmed	ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia.	ADAMTS1 ADAMTS12	5.19e-05	4	103	2	29135310
Pubmed	Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.	KCNA2 KCNA5 KCNA6	6.24e-05	26	103	3	7905852
Pubmed	Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila.	RBBP4 MORF4L1	8.64e-05	5	103	2	29158494
Pubmed	Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.	INSIG1 INSIG2	8.64e-05	5	103	2	29374057
Pubmed	A mechanism for combinatorial regulation of electrical activity: Potassium channel subunits capable of functioning as Src homology 3-dependent adaptors.	KCNA2 KCNA5	8.64e-05	5	103	2	11149959
Pubmed	Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.	INSIG1 INSIG2	8.64e-05	5	103	2	22143767
Pubmed	Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.	KCNA2 KCNA6	8.64e-05	5	103	2	21233214
Pubmed	Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene.	INSIG1 INSIG2	8.64e-05	5	103	2	30733434
Pubmed	Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells.	INSIG1 SREBF1	8.64e-05	5	103	2	22690709
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	INSIG1 SREBF1 FASN PIK3R2 DHCR7 INSIG2	1.04e-04	250	103	6	18660489
Pubmed	Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.	KCNA2 KCNA5 KCNA6	1.07e-04	31	103	3	8034307
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RNPEPL1 SREBF1 PEX6 PFAS KDM6B SYNE4 LPIN3 FASN FAT1 PWWP2B SOWAHB CREB3	1.07e-04	1105	103	12	35748872
Pubmed	Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations.	KCNA5 KCNA6	1.29e-04	6	103	2	8530061
Pubmed	Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology.	SARM1 NF1	1.29e-04	6	103	2	21555464
Pubmed	KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.	SREBF1 FASN	1.29e-04	6	103	2	27545894
Pubmed	Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.	KCNA2 KCNA6	1.29e-04	6	103	2	14686897
Pubmed	Unsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination step.	INSIG1 SREBF1	1.29e-04	6	103	2	18835813
Pubmed	HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons.	GRIN3A GRIN3B	1.81e-04	7	103	2	11606043
Pubmed	Pore size matters for potassium channel conductance.	KCNA2 KCNA6	1.81e-04	7	103	2	27619418
Pubmed	Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.	AXL PIK3R2	1.81e-04	7	103	2	9178760
Pubmed	The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site.	GRIN3A GRIN3B	1.81e-04	7	103	2	14644469
Pubmed	Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site.	GRIN3A GRIN3B	1.81e-04	7	103	2	12775422
Pubmed	Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.	GRIN3A GRIN3B	1.81e-04	7	103	2	7569905
Pubmed	HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.	GRIN3A GRIN3B	1.81e-04	7	103	2	22940423
GeneFamily	Immunoglobulin like domain containing	SLAMF8 CILP AXL KIRREL2 CCDC141 FCRL6 BSG IGSF23	8.73e-07	193	71	8	594
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN3A GRIN3B	3.15e-04	7	71	2	1201
GeneFamily	Potassium voltage-gated channels	KCNA2 KCNA5 KCNA6	5.17e-04	40	71	3	274
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	RBBP4 MORF4L1	9.78e-04	12	71	2	1243
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS1 ADAMTS12	2.49e-03	19	71	2	50
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	KIRREL2 BSG FGFR4 MYBPHL	3.70e-03	161	71	4	593
ToppCell	Tracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	OPN4 ADAMTS1 AXL WNT6 ADAMTS12 OLFML2A KCNA5 MYBPHL	2.11e-08	199	103	8	aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCell	Tracheal-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	OPN4 ADAMTS1 WNT6 ADAMTS12 OLFML2A KCNA5 MYBPHL	4.12e-07	199	103	7	cefc3b50f65e95da850e4720c7b44bf584073491
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-liver_dendritic_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SLAMF8 SARM1 PEX6 ZNF419 CLEC17A RUSC1-AS1	1.59e-06	154	103	6	acfbde0fbc09fd69af62a81f8f63e14e36dd1ae0
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CILP WNT6 ADAMTS12 LPIN3 SSC5D	4.18e-06	103	103	5	39d8cfb899ca88c72ebe021d66cc21ae2eb6a1cc
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CILP WNT6 ADAMTS12 LPIN3 SSC5D	4.18e-06	103	103	5	01a7baaa0c3903bd00e37717856d2c1ac21bf2c8
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPH WNT6 SLC22A23 KCNA2 KCNA6 FGFR4	5.02e-06	188	103	6	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	Tracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OPN4 ADAMTS1 AXL WNT6 ADAMTS12 TACC1	7.15e-06	200	103	6	9d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCell	Tracheal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OPN4 ADAMTS1 AXL WNT6 ADAMTS12 TACC1	7.15e-06	200	103	6	78cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WNT6 PFAS LPIN3 KCNA2 KCNA5	2.94e-05	154	103	5	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	CILP DLL4 ERVMER34-1 ADAMTS12 FGFR4	3.97e-05	164	103	5	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LINC02908 KCNA5 CLEC17A IGHD TMEM131L	4.09e-05	165	103	5	7039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LINC02908 KCNA5 CLEC17A IGHD TMEM131L	4.09e-05	165	103	5	d2c79653710b139794170f3d72f11392fc548ac7
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 AXL CLEC7A SLC13A3 KCNA2	4.71e-05	170	103	5	067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ADAMTS1 WNT6 ADAMTS12 OLFML2A KCNA5	5.56e-05	176	103	5	2015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IBA57 WNT6 SREBF1 KCNA2 KCNA6	5.56e-05	176	103	5	792f414f5092aba14260b8e16378e793a822498e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 SLC22A23 KCNA2 KCNA6 FGFR4	6.18e-05	180	103	5	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 SLC22A23 KCNA2 KCNA6 FGFR4	6.18e-05	180	103	5	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 SLC22A23 KCNA2 KCNA6 NCAN	6.51e-05	182	103	5	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CLEC7A CCDC141 LINC02908 KCNA5 CLEC17A	6.68e-05	183	103	5	a97f052950429245c3231464271e1ba539863bba
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WNT6 SLC22A23 KCNA2 KCNA6 FGFR4	6.86e-05	184	103	5	e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	OLFML2A FAT1 STARD9 TPRG1 FGFR4	7.04e-05	185	103	5	0094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCell	droplet-Heart-HEART-1m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPH WNT6 SLC22A23 KCNA2 KCNA6	7.78e-05	189	103	5	a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AMPH CILP ADAMTS1 AXL FAT1	7.78e-05	189	103	5	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPH WNT6 SLC22A23 KCNA2 KCNA6	7.78e-05	189	103	5	4e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AMPH CILP ADAMTS1 AXL FAT1	7.98e-05	190	103	5	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 ATP6V0B CLEC7A CCDC141 BSG	8.18e-05	191	103	5	f4a425a0e7382d01b5a8201c2c186966bb47011b
ToppCell	facs-Brain_Myeloid-Striatum_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 ATP6V0B CLEC7A CCDC141 BSG	8.18e-05	191	103	5	de3b696de29a4b10c0870dec1792c7be9651d31e
ToppCell	facs-Brain_Myeloid-Striatum_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 ATP6V0B CLEC7A CCDC141 BSG	8.18e-05	191	103	5	e0c9f49d2e26ccbc88b4ceae9918922f4b7cfd4d
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 ATP6V0B CLEC7A CCDC141 BSG	8.18e-05	191	103	5	fe17533b970540ad3339722e13dbf4029b20a756
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 ATP6V0B CLEC7A CCDC141 BSG	8.18e-05	191	103	5	d031430687b876930e9f718da20679938fd05edc
ToppCell	distal-Endothelial-Bronchial_Vessel_2-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DLL4 SLC22A23 INSIG1 NF1 DHCR7	9.46e-05	197	103	5	9fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCell	distal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DLL4 SLC22A23 INSIG1 NF1 DHCR7	9.69e-05	198	103	5	f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCell	T/NK_cells-CD8+_Naive_T_cell\|T/NK_cells / Lineage and Cell class	ATP6V0B RNF213 FCRL6 BSG IL2RB	9.69e-05	198	103	5	5b78118af2283f2e1ad9c6a6ab448a018bf2f2e0
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 ADAMTS12 OLFML2A STARD9 TACC1	9.92e-05	199	103	5	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 WNT6 ADAMTS12 OLFML2A TACC1	9.92e-05	199	103	5	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CILP ADAMTS12 LPIN3 SSC5D	9.99e-05	104	103	4	11d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CILP ADAMTS12 LPIN3 SSC5D	9.99e-05	104	103	4	424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CILP ADAMTS12 LPIN3 SSC5D	9.99e-05	104	103	4	9b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CILP ADAMTS1 FAT1 KCNA5 TMEM131L	1.02e-04	200	103	5	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	AMPH CILP ADAMTS1 FAT1 TMEM131L	1.02e-04	200	103	5	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	AMPH CILP ADAMTS1 FAT1 KCNA5	1.02e-04	200	103	5	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLAMF8 WNT6 ADAMTS12 FGFR4	1.04e-04	105	103	4	cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLAMF8 WNT6 ADAMTS12 FGFR4	1.04e-04	105	103	4	c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLAMF8 WNT6 ADAMTS12 FGFR4	1.04e-04	105	103	4	dc5f6d62945a699734a71b8ab1d4266db6fb2918
Drug	CID10948590	KCNA2 KCNA5 KCNA6	1.78e-06	6	103	3	CID010948590
Disease	colon cancer (is_marker_for)	ATG101 NF1 PIK3R2 FGFR4	4.90e-05	59	100	4	DOID:219 (is_marker_for)
Disease	MAGUK p55 subfamily member 7 measurement	RNPEPL1 SARM1	6.79e-05	4	100	2	EFO_0802724
Disease	Liposarcoma, Pleomorphic	FASN NF1	6.79e-05	4	100	2	C0205825
Disease	intestinal permeability measurement	ADAMTS1 PEX6 GRIN3A	9.28e-05	26	100	3	EFO_0011031
Disease	Schwannomatosis, Plexiform	AXL NF1	1.13e-04	5	100	2	C0751374
Disease	Profound Mental Retardation	PEX6 KDM6B FASN KCNA2 NF1	1.13e-04	139	100	5	C0020796
Disease	Mental Retardation, Psychosocial	PEX6 KDM6B FASN KCNA2 NF1	1.13e-04	139	100	5	C0025363
Disease	Mental deficiency	PEX6 KDM6B FASN KCNA2 NF1	1.13e-04	139	100	5	C0917816
Disease	liposarcoma	FASN NF1	1.69e-04	6	100	2	C0023827
Disease	Liposarcoma, well differentiated	FASN NF1	1.69e-04	6	100	2	C1370889
Disease	Liposarcoma, Dedifferentiated	FASN NF1	1.69e-04	6	100	2	C0205824
Disease	Neurilemmoma	AXL NF1	1.69e-04	6	100	2	C0027809
Disease	Adenoid Cystic Carcinoma	KDM6B FAT1 MORF4L1 FGFR4	3.79e-04	100	100	4	C0010606
Disease	tumor necrosis factor receptor superfamily member 16 measurement	SARM1 IGHD	4.03e-04	9	100	2	EFO_0802168
Disease	HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA	AXL CCDC141	6.13e-04	11	100	2	146110
Disease	Hypogonadotropic hypogonadism 7 with or without anosmia	AXL CCDC141	6.13e-04	11	100	2	cv:C0342384
Disease	retinopathy of prematurity (biomarker_via_orthology)	EPOR DLL4	7.34e-04	12	100	2	DOID:13025 (biomarker_via_orthology)
Disease	renal cell carcinoma (is_marker_for)	DLL4 PFAS KDM6B BSG	9.60e-04	128	100	4	DOID:4450 (is_marker_for)
Disease	femoral neck bone geometry	KCNA5 FGFR4	1.01e-03	14	100	2	EFO_0004511
Disease	Moyamoya Disease	RNF213 NF1	1.50e-03	17	100	2	C0026654
Disease	squamous cell carcinoma	ADAMTS12 UBAC2 TPRG1	1.55e-03	67	100	3	EFO_0000707
Disease	Idiopathic hypogonadotropic hypogonadism	AXL CCDC141	1.68e-03	18	100	2	C0342384
Disease	sensorineural hearing loss (implicated_via_orthology)	OPN4 DNAH9	1.87e-03	19	100	2	DOID:10003 (implicated_via_orthology)
Disease	apolipoprotein B measurement	SARM1 PEX6 LMAN1L NF1 NCAN INSIG2 MYBPHL IGSF23	1.89e-03	663	100	8	EFO_0004615
Disease	epilepsy (implicated_via_orthology)	SLC13A3 KCNA2 KCNA5 KCNA6	2.33e-03	163	100	4	DOID:1826 (implicated_via_orthology)
Disease	Giant Cell Glioblastoma	FAT1 NF1 TACC1	2.95e-03	84	100	3	C0334588
Disease	nephrotic syndrome (implicated_via_orthology)	KIRREL2 FAT1	2.99e-03	24	100	2	DOID:1184 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MAFSPWQILSPVQWA	TACC1	1	O75410
HWEIIPSDPFWVPTT	EFL1	1056	Q7Z2Z2
AWLTVLPEEDPTWTA	FGFR4	346	P22455
VWTISIFISMPPLFW	HTR1E	146	P28566
VALAASVPDWWPTVS	IBA57	341	Q5T440
WPGTFSLIIEAWHAP	DLL4	111	Q9NR61
SWFSPTIIFDNWIPL	DHCR7	166	Q9UBM7
DSNESKSIVWYPPWA	ARMCX3	66	Q9UH62
PDIWFDFETMARPWT	ARMCX6	56	Q7L4S7
RESWWPPFSTVMEGL	ADAMTS12	1206	P58397
EWPALLVSSTGWTEF	ALG1L	21	Q6GMV1
PWDLWTTSTDLVQPA	AMPH	381	P49418
AIPTFSAWVIEEWGE	ADAMTS1	851	Q9UHI8
PLLTSSWDEWVPESR	MORF4L1	86	Q9UBU8
YHWDTSDWMPSVPLP	FAT1	4381	Q14517
ATIWWPLSDPTYATV	PADI6	71	Q6TGC4
PASKSWSWATLEVPV	LPIN3	341	Q9BQK8
SQFPSIPDAFWWAVV	KCNA2	356	P16389
PASSHWEFWVPSTPV	MAFIP	21	Q8WZ33
TPWRVSFSWSPVLLA	PSMG3-AS1	26	Q96PY0
TASVPQSIPEWLEFW	ITPRID1	126	Q6ZRS4
ASWWAFVEPPAVSPE	MYO15A	716	Q9UKN7
SPIFLPTDSEWDWLL	ALOXE3	376	Q9BYJ1
WSRASVPFSAWEVEV	LMAN1L	81	Q9HAT1
PELVFVPASASTWWT	ERVMER34-1	56	Q9H9K5
SWWPILDDLYASNIP	KDM6B	1436	O15054
FTPASNWLVPWLPAS	FCRL6	301	Q6DN72
WAPVRAPIYVSSWAV	PCSK4	26	Q6UW60
PSTWPYEEITSPWIA	KIAA1586	636	Q9HCI6
WLPSEESTLWSSLSP	PEX6	421	Q13608
EEVIATIFSSAWWVP	INSIG1	116	O15503
EPQWVPATWISSDTE	MPP4	621	Q96JB8
LFSVPWLVFPEAAVW	GPR152	161	Q8TDT2
DVIASIFSSAWWVPP	INSIG2	61	Q9Y5U4
LVQPAPSAIWDFWEA	POM121L12	256	Q8N7R1
PSAIWDFWEATTPSC	POM121L12	261	Q8N7R1
KISDFSWNPNEPWVI	RBBP4	376	Q09028
DTAAPIGAFMWPLHW	GRIN3A	661	Q8TCU5
GTWAAAWVPLPTVDV	OPN4	51	Q9UHM6
PAPRTDWSLSDVDQW	PIK3R2	151	O00459
LWSPWTPLDESFQWL	FANCD2OS	6	Q96PS1
WDEGDWTLSIPPDMS	NBPF3	346	Q9H094
PTWESLDARQLPAWF	FUCA2	36	Q9BTY2
PFSDECIPWEVWTVK	ATG101	111	Q9BSB4
WVVTMDPEPVLSWTF	IGSF23	71	A1L1A6
SIPDAFWWAVVTMTT	KCNA5	466	P22460
DDDSLFPSIPDAFWW	KCNA6	401	P17658
FPSIPDAFWWAVVTM	KCNA6	406	P17658
EVTGFPEPTLTWWVA	CCDC141	1431	Q6ZP82
WSQAWPDPDVLEISM	LINC02908	41	Q6ZV77
LSSPQYSPWELTELW	B3GALNT2	471	Q8NCR0
EFTTWSPWSQPLAFR	IL2RB	216	P14784
STTFWAWSVLRVPAP	IGHD	331	P01880
VCKSESVPPVTDWAW	BSG	241	P35613
SVPPVTDWAWYKITD	BSG	246	P35613
SSDPAWAVEWIELPR	FAM131A	31	Q6UXB0
DVWGFSATLEWTPPQ	MYBPHL	156	A2RUH7
FWNTIVKVFPTWLAP	SELENOI	36	Q9C0D9
GFWSAWSEPVSLLTP	EPOR	231	P19235
VFASPAPDAVVWSWD	KIRREL2	421	Q6UWL6
PWIQVPTSWVYLTAA	SDR42E2	301	A6NKP2
LEAWTGDFTMPSTVW	DNAH9	4331	Q9NYC9
VLLSPDFLWDVPSNW	FASN	1626	P49327
DWALPLSEVPSDWEV	CREB3	36	O43889
PSWREAKVSWFGSPT	PWWP2B	521	Q6NUJ5
WWFDFKAPNTETEPL	SLC13A3	401	Q8WWT9
PTWTLDWNVLPAAVS	GSTCD	396	Q8NEC7
LLPDVVYEDTTPWKW	OLFML2A	501	Q68BL7
DTASPIGAFMWPLHW	GRIN3B	561	O60391
WIDSPAPERWMVSSW	RTL1	381	A6NKG5
STDAPAIWWLDPELT	RNPEPL1	171	Q9HAU8
LMWLPSLPALWAAST	SSPOP	2431	A2VEC9
RLLTELESPAWWPFS	SNAP47	211	Q5SQN1
VPGPSWEESFWRLTV	TMEM131L	861	A2VDJ0
WAPSSLPTSTELEWD	SYNE4	236	Q8N205
PPVTTWDWTRAEKTF	SNTG1	321	Q9NSN8
NWTSLPTTPFATAPW	SLC22A23	151	A1A5C7
SAPRVTISPEFWTWA	PNMA3	131	Q9UL41
PMLASWPTGEVWLST	NCAN	436	O14594
AGLWEFPSVTWEPSE	MUTYH	396	Q9UIF7
AWAWRSSDPPPAFSV	RUSC1-AS1	211	Q66K80
WPWIPSLSDVAAVFF	SLF2	846	Q8IX21
PLSRVWAAVSDPTVW	STARD9	4551	Q9P2P6
PGLDSISDPFSWSWI	SSC5D	571	A1L4H1
LFPVVPDESWESWAG	SOWAHB	361	A6NEL2
FFVDGDWSVLSTPWE	SREBF1	771	P36956
PADTLESPGEWTTWF	CILP	46	O75339
PQTEVPWLWEDGSTF	CLEC7A	186	Q9BXN2
WLDGSPVTLSFWEPE	CLEC17A	326	Q6ZS10
DTPPWARDLWMFIFS	RNF213	3656	Q63HN8
ATAPMWPNTFWSAAE	WDTC1	141	Q8N5D0
VWSYWMTIFTSPASP	ZDHHC20	66	Q5W0Z9
SWSLPPWRAYVAAAV	SPNS3	36	Q6ZMD2
LPSVPSWKEAEVQTW	SARM1	406	Q6SZW1
QWAWRPPPFDTLTTS	PFAS	1306	O15067
DVAWFLTETSPFMWS	ATP6V0B	36	Q99437
RWNPWSTEVPYATFT	TPRG1	181	Q6ZUI0
QLVKEPSTPAFSWPW	AXL	436	P30530
WWAVGSPLVMDPTSI	WNT6	26	Q9Y6F9
WNPDAPVETFWEISS	NF1	561	P21359
PVSWDLATVTPWDSC	SLAMF8	206	Q9P0V8
QLESWEEPFMPAWEV	ZNF773	66	Q6PK81
VPTWSDFPSWAMELL	ZFR	936	Q96KR1
IPSWMAKFFSWTLEP	UBAC2	206	Q8NBM4
SVFFVWELKWTEEPP	TRAPPC10	1006	P48553
ITQLESWEEPFMPAW	ZNF419	76	Q96HQ0
SWEEPFMPAWEVVTS	ZNF419	81	Q96HQ0
WVPSWVDVTPVSRAE	ZNF584	76	Q8IVC4