Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	MYO1E SHROOM2 FMNL1 PTK2 PHACTR2 CD2AP SYNPO2L	2.59e-07	479	20	7	GO:0003779
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1L TAF1	9.51e-06	5	20	2	GO:0061628
GeneOntologyMolecularFunction	histone acetyltransferase activity	TAF1L JADE2 TAF1	1.74e-05	51	20	3	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	TAF1L JADE2 TAF1	2.18e-05	55	20	3	GO:0061733
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	TAF1L JADE2 TAF1	2.84e-05	60	20	3	GO:0034212
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1L TAF1	3.42e-05	9	20	2	GO:0001181
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYO1E SHROOM2 FMNL1 PTK2 PHACTR2 CD2AP SYNPO2L	6.17e-05	1099	20	7	GO:0008092
GeneOntologyMolecularFunction	N-acetyltransferase activity	TAF1L JADE2 TAF1	6.23e-05	78	20	3	GO:0008080
GeneOntologyMolecularFunction	actin filament binding	MYO1E SHROOM2 FMNL1 CD2AP	6.83e-05	227	20	4	GO:0051015
GeneOntologyMolecularFunction	histone modifying activity	PHF2 TAF1L JADE2 TAF1	7.07e-05	229	20	4	GO:0140993
GeneOntologyMolecularFunction	methylated histone binding	PHF2 TAF1L TAF1	8.34e-05	86	20	3	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	PHF2 TAF1L TAF1	8.93e-05	88	20	3	GO:0140034
GeneOntologyMolecularFunction	N-acyltransferase activity	TAF1L JADE2 TAF1	1.38e-04	102	20	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	TAF1L JADE2 TAF1	1.47e-04	104	20	3	GO:0016407
GeneOntologyMolecularFunction	RNA polymerase II core promoter sequence-specific DNA binding	TAF1L TAF1	2.82e-04	25	20	2	GO:0000979
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	TAF1L TAF1	3.30e-04	27	20	2	GO:0001091
GeneOntologyMolecularFunction	lysine-acetylated histone binding	TAF1L TAF1	4.08e-04	30	20	2	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	TAF1L TAF1	4.36e-04	31	20	2	GO:0140033
GeneOntologyMolecularFunction	TBP-class protein binding	TAF1L TAF1	4.94e-04	33	20	2	GO:0017025
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	TAF1L TAF1	5.88e-04	36	20	2	GO:0140416
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	TAF1L TAF1	6.22e-04	37	20	2	GO:0061631
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	TAF1L TAF1	8.40e-04	43	20	2	GO:0061650
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase binding	PTK2 CD2AP	8.40e-04	43	20	2	GO:0043548
GeneOntologyMolecularFunction	modification-dependent protein binding	PHF2 TAF1L TAF1	1.08e-03	206	20	3	GO:0140030
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	TAF1L TAF1	1.23e-03	52	20	2	GO:0016251
GeneOntologyMolecularFunction	core promoter sequence-specific DNA binding	TAF1L TAF1	1.37e-03	55	20	2	GO:0001046
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	TAF1L JADE2 TAF1	1.64e-03	238	20	3	GO:0016747
GeneOntologyMolecularFunction	general transcription initiation factor binding	TAF1L TAF1	1.85e-03	64	20	2	GO:0140296
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	TAF1L TAF1	1.97e-03	66	20	2	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	TAF1L TAF1	1.97e-03	66	20	2	GO:0001098
GeneOntologyMolecularFunction	general transcription initiation factor activity	TAF1L TAF1	2.09e-03	68	20	2	GO:0140223
GeneOntologyMolecularFunction	histone binding	PHF2 TAF1L TAF1	2.23e-03	265	20	3	GO:0042393
GeneOntologyMolecularFunction	p53 binding	TAF1L TAF1	2.67e-03	77	20	2	GO:0002039
GeneOntologyMolecularFunction	promoter-specific chromatin binding	TAF1L TAF1	3.09e-03	83	20	2	GO:1990841
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TAF1L PTK2 PIK3R3 TAF1	4.85e-03	709	20	4	GO:0016773
GeneOntologyMolecularFunction	kinase activity	TAF1L PTK2 PIK3R3 TAF1	6.31e-03	764	20	4	GO:0016301
GeneOntologyMolecularFunction	beta-catenin binding	SHROOM2 CD2AP	6.34e-03	120	20	2	GO:0008013
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TAF1L JADE2 TAF1	1.12e-02	473	20	3	GO:0004842
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TAF1L PTK2 PIK3R3 TAF1	1.28e-02	938	20	4	GO:0016772
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TAF1L JADE2 TAF1	1.38e-02	512	20	3	GO:0019787
GeneOntologyMolecularFunction	nuclear receptor binding	TAF1L TAF1	1.48e-02	187	20	2	GO:0016922
GeneOntologyMolecularFunction	aminoacyltransferase activity	TAF1L JADE2 TAF1	1.53e-02	532	20	3	GO:0016755
GeneOntologyBiologicalProcess	actin cytoskeleton organization	MYO1E SHROOM2 FMNL1 PHACTR2 CD2AP SYNPO2L	8.29e-05	803	20	6	GO:0030036
GeneOntologyBiologicalProcess	negative regulation of anoikis	PTK2 PIK3R3	1.51e-04	19	20	2	GO:2000811
GeneOntologyBiologicalProcess	actin filament-based process	MYO1E SHROOM2 FMNL1 PHACTR2 CD2AP SYNPO2L	1.67e-04	912	20	6	GO:0030029
GeneOntologyBiologicalProcess	podocyte differentiation	MYO1E CD2AP	2.04e-04	22	20	2	GO:0072112
GeneOntologyBiologicalProcess	glomerular epithelial cell differentiation	MYO1E CD2AP	2.04e-04	22	20	2	GO:0072311
GeneOntologyBiologicalProcess	renal filtration cell differentiation	MYO1E CD2AP	2.04e-04	22	20	2	GO:0061318
GeneOntologyBiologicalProcess	glomerular epithelium development	MYO1E CD2AP	2.23e-04	23	20	2	GO:0072010
GeneOntologyBiologicalProcess	regulation of anoikis	PTK2 PIK3R3	2.86e-04	26	20	2	GO:2000209
GeneOntologyBiologicalProcess	substrate-dependent cell migration	FMNL1 CD2AP	5.21e-04	35	20	2	GO:0006929
GeneOntologyBiologicalProcess	anoikis	PTK2 PIK3R3	5.83e-04	37	20	2	GO:0043276
GeneOntologyBiologicalProcess	chromatin remodeling	PHF2 ZNF827 TAF1L JADE2 TAF1	5.84e-04	741	20	5	GO:0006338
GeneOntologyCellularComponent	cell cortex	MYO1E SHROOM2 FMNL1 PTK2 CD2AP	2.13e-05	371	20	5	GO:0005938
GeneOntologyCellularComponent	actin cytoskeleton	MYO1E SHROOM2 PTK2 CD2AP SYNPO2L	1.72e-04	576	20	5	GO:0015629
GeneOntologyCellularComponent	pronucleus	TAF1L TAF1	3.24e-04	28	20	2	GO:0045120
GeneOntologyCellularComponent	MLL1 complex	TAF1L TAF1	4.24e-04	32	20	2	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	TAF1L TAF1	4.51e-04	33	20	2	GO:0044665
GeneOntologyCellularComponent	transcription factor TFIID complex	TAF1L TAF1	9.16e-04	47	20	2	GO:0005669
GeneOntologyCellularComponent	cell-cell junction	MYO1E SHROOM2 PTK2 CD2AP	2.14e-03	591	20	4	GO:0005911
GeneOntologyCellularComponent	histone methyltransferase complex	TAF1L TAF1	2.31e-03	75	20	2	GO:0035097
GeneOntologyCellularComponent	RNA polymerase II, holoenzyme	TAF1L TAF1	3.24e-03	89	20	2	GO:0016591
GeneOntologyCellularComponent	cortical actin cytoskeleton	MYO1E SHROOM2	3.53e-03	93	20	2	GO:0030864
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	TAF1L PIK3R3 TAF1	3.80e-03	335	20	3	GO:0061695
GeneOntologyCellularComponent	methyltransferase complex	TAF1L TAF1	4.73e-03	108	20	2	GO:0034708
GeneOntologyCellularComponent	nuclear DNA-directed RNA polymerase complex	TAF1L TAF1	5.16e-03	113	20	2	GO:0055029
GeneOntologyCellularComponent	DNA-directed RNA polymerase complex	TAF1L TAF1	5.43e-03	116	20	2	GO:0000428
GeneOntologyCellularComponent	endocytic vesicle	MYO1E FMNL1 CD2AP	5.56e-03	384	20	3	GO:0030139
GeneOntologyCellularComponent	RNA polymerase complex	TAF1L TAF1	5.71e-03	119	20	2	GO:0030880
HumanPheno	Foamy urine	MYO1E CD2AP	2.13e-04	31	4	2	HP:0031504
HumanPheno	Minimal change glomerulonephritis	MYO1E CD2AP	3.22e-04	38	4	2	HP:0012579
HumanPheno	Diffuse mesangial sclerosis	MYO1E CD2AP	3.75e-04	41	4	2	HP:0001967
HumanPheno	Peritonitis	MYO1E CD2AP	4.33e-04	44	4	2	HP:0002586
HumanPheno	Abnormal glomerular mesangium morphology	MYO1E CD2AP	5.15e-04	48	4	2	HP:0001966
HumanPheno	Abnormal macroscopic urine appearance	MYO1E CD2AP	7.53e-04	58	4	2	HP:0033072
HumanPheno	Abnormal renal cortex morphology	MYO1E CD96 CD2AP	9.37e-04	320	4	3	HP:0011035
HumanPheno	Abnormal peritoneum morphology	MYO1E CD2AP	9.46e-04	65	4	2	HP:0002585
Domain	TAF_II_230-bd	TAF1L TAF1	9.80e-07	2	19	2	IPR009067
Domain	DUF3591	TAF1L TAF1	9.80e-07	2	19	2	PF12157
Domain	TFIID_sub1_DUF3591	TAF1L TAF1	9.80e-07	2	19	2	IPR022591
Domain	TBP-binding	TAF1L TAF1	9.80e-07	2	19	2	PF09247
Domain	TAF1_animal	TAF1L TAF1	9.80e-07	2	19	2	IPR011177
Domain	-	TAF1L TAF1	9.80e-07	2	19	2	1.10.1100.10
Domain	Bromodomain_CS	TAF1L TAF1	3.14e-04	26	19	2	IPR018359
Domain	BROMODOMAIN_1	TAF1L TAF1	6.39e-04	37	19	2	PS00633
Domain	Bromodomain	TAF1L TAF1	6.74e-04	38	19	2	PF00439
Domain	BROMODOMAIN_2	TAF1L TAF1	7.85e-04	41	19	2	PS50014
Domain	BROMO	TAF1L TAF1	8.24e-04	42	19	2	SM00297
Domain	Bromodomain	TAF1L TAF1	8.24e-04	42	19	2	IPR001487
Domain	-	TAF1L TAF1	8.24e-04	42	19	2	1.20.920.10
Domain	Zinc_finger_PHD-type_CS	PHF2 JADE2	1.96e-03	65	19	2	IPR019786
Domain	PHD	PHF2 JADE2	2.60e-03	75	19	2	PF00628
Domain	Znf_PHD-finger	PHF2 JADE2	2.88e-03	79	19	2	IPR019787
Domain	PHD	PHF2 JADE2	3.64e-03	89	19	2	SM00249
Domain	Znf_PHD	PHF2 JADE2	3.80e-03	91	19	2	IPR001965
Domain	ZF_PHD_2	PHF2 JADE2	4.14e-03	95	19	2	PS50016
Domain	ZF_PHD_1	PHF2 JADE2	4.22e-03	96	19	2	PS01359
Domain	PDZ	SHROOM2 SYNPO2L	8.90e-03	141	19	2	PF00595
Domain	Znf_FYVE_PHD	PHF2 JADE2	9.64e-03	147	19	2	IPR011011
Domain	PDZ	SHROOM2 SYNPO2L	9.76e-03	148	19	2	SM00228
Domain	-	SHROOM2 SYNPO2L	1.00e-02	150	19	2	2.30.42.10
Domain	PDZ	SHROOM2 SYNPO2L	1.01e-02	151	19	2	PS50106
Domain	PDZ	SHROOM2 SYNPO2L	1.03e-02	152	19	2	IPR001478
Domain	SH3_1	MYO1E CD2AP	1.19e-02	164	19	2	PF00018
Domain	Ubiquitin-rel_dom	RGL3 PTK2	1.48e-02	184	19	2	IPR029071
Domain	SH3	MYO1E CD2AP	2.00e-02	216	19	2	PS50002
Domain	SH3	MYO1E CD2AP	2.00e-02	216	19	2	SM00326
Domain	SH3_domain	MYO1E CD2AP	2.07e-02	220	19	2	IPR001452
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	MYO1E PTK2 CD2AP	6.82e-05	72	16	3	M39403
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	MYO1E PTK2 CD2AP	7.11e-05	73	16	3	MM15906
Pathway	PID_NEPHRIN_NEPH1_PATHWAY	CD2AP PIK3R3	5.51e-04	31	16	2	M193
Pathway	KEGG_BASAL_TRANSCRIPTION_FACTORS	TAF1L TAF1	7.03e-04	35	16	2	M4864
Pathway	PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY	PTK2 PIK3R3	7.03e-04	35	16	2	M127
Pathway	PID_ERBB1_INTERNALIZATION_PATHWAY	PTK2 PIK3R3	9.65e-04	41	16	2	M214
Pathway	WP_NEPHROTIC_SYNDROME	MYO1E CD2AP	1.16e-03	45	16	2	M39864
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	TAF1L TAF1	1.21e-03	46	16	2	MM15949
Pathway	REACTOME_HIV_TRANSCRIPTION_INITIATION	TAF1L TAF1	1.27e-03	47	16	2	M29568
Pathway	REACTOME_RNA_POLYMERASE_II_PROMOTER_ESCAPE	TAF1L TAF1	1.32e-03	48	16	2	MM15424
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1L TAF1	3.14e-07	2	20	2	38804708
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1L TAF1	3.14e-07	2	20	2	10070062
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1L TAF1	3.14e-07	2	20	2	22842574
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1L TAF1	3.14e-07	2	20	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1L TAF1	3.14e-07	2	20	2	34403156
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FNBP4 PHF2 SHROOM2 ZNF827 JADE2 PTK2 CD2AP PIK3R3	8.80e-07	1489	20	8	28611215
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1L TAF1	9.42e-07	3	20	2	16822332
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1L TAF1	9.42e-07	3	20	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1L TAF1	9.42e-07	3	20	2	16407123
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1L TAF1	9.42e-07	3	20	2	11592977
Pubmed	Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling.	PTK2 CD2AP	3.14e-06	5	20	2	15632162
Pubmed	Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.	MYO1E PTK2	4.71e-06	6	20	2	28348210
Pubmed	Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.	TAF1L TAF1	4.71e-06	6	20	2	19959467
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	TAF1L TAF1	8.78e-06	8	20	2	1974879
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	TAF1L TAF1	8.78e-06	8	20	2	2034279
Pubmed	Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes.	PTK2 PIK3R3	8.78e-06	8	20	2	22402981
Pubmed	Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.	TAF1L TAF1	8.78e-06	8	20	2	31012985
Pubmed	Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.	TAF1L TAF1	8.78e-06	8	20	2	8468051
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	TAF1L TAF1	8.78e-06	8	20	2	1675191
Pubmed	HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.	TAF1L TAF1	1.13e-05	9	20	2	9751712
Pubmed	Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.	TAF1L TAF1	1.13e-05	9	20	2	7874112
Pubmed	The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.	TAF1L TAF1	1.13e-05	9	20	2	12665565
Pubmed	Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.	TAF1L TAF1	1.41e-05	10	20	2	2055107
Pubmed	Characterization of a murine gene expressed from the inactive X chromosome.	TAF1L TAF1	1.72e-05	11	20	2	2034278
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	TAF1L TAF1	2.44e-05	13	20	2	1740345
Pubmed	The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.	TAF1L TAF1	2.44e-05	13	20	2	7805729
Pubmed	Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.	TAF1L TAF1	2.44e-05	13	20	2	8012115
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	TAF1L TAF1	2.44e-05	13	20	2	1772416
Pubmed	Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.	TAF1L TAF1	2.44e-05	13	20	2	11557891
Pubmed	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.	TAF1L TAF1	3.28e-05	15	20	2	14580349
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	TAF1L FMNL1 CD2AP TAF1	5.34e-05	370	20	4	22922362
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	MYO1E FMNL1 STIP1	7.37e-05	143	20	3	30397336
Pubmed	Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.	CD2AP PIK3R3	1.35e-04	30	20	2	38310234
Pubmed	Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.	TAF1L TAF1	1.45e-04	31	20	2	25838543
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	FNBP4 PHF2 TAF1L CD2AP TAF1	1.69e-04	954	20	5	36373674
Pubmed	Huntingtin interacting proteins are genetic modifiers of neurodegeneration.	FNBP4 STIP1 PIK3R3	1.90e-04	197	20	3	17500595
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	TAF1L TAF1	2.80e-04	43	20	2	18722179
Pubmed	TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.	TAF1L TAF1	3.20e-04	46	20	2	25209997
Pubmed	Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.	TAF1L TAF1	3.79e-04	50	20	2	27026076
Pubmed	The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.	TAF1L TAF1	4.09e-04	52	20	2	28893950
Pubmed	Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.	TAF1L TAF1	4.09e-04	52	20	2	35361962
Pubmed	New nomenclature for chromatin-modifying enzymes.	TAF1L TAF1	4.92e-04	57	20	2	18022353
GeneFamily	PHD finger proteins	PHF2 JADE2	2.14e-03	90	14	2	88
GeneFamily	PDZ domain containing	SHROOM2 SYNPO2L	5.98e-03	152	14	2	1220
Coexpression	GSE360_CTRL_VS_L_MAJOR_DC_UP	MYO1E PTK2 STIP1 CD2AP	1.42e-05	199	20	4	M5145
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE	FNBP4 GON4L CD96 PTK2 PHACTR2	2.35e-05	474	20	5	M40991
Coexpression	LAKE_ADULT_KIDNEY_C16_COLLECTING_SYSTEM_PRINCIPAL_CELLS_CORTEX	MYO1E PTK2 CD2AP	1.62e-04	141	20	3	M39235
Coexpression	WENDT_COHESIN_TARGETS_UP	PTK2 PIK3R3	2.71e-04	32	20	2	M10024
Coexpression	GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP	FNBP4 PTK2 CD2AP	2.92e-04	172	20	3	M2945
Coexpression	GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN	FNBP4 JADE2 PTK2	4.34e-04	197	20	3	M8611
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	GON4L TAF1L CD2AP TAF1	4.40e-04	484	20	4	MM999
Coexpression	GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_UP	FNBP4 PTK2 CD2AP	4.40e-04	198	20	3	M9035
Coexpression	GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP	FNBP4 GON4L JADE2	4.40e-04	198	20	3	M3108
Coexpression	GSE11057_PBMC_VS_MEM_CD4_TCELL_DN	JADE2 CD96 PHACTR2	4.40e-04	198	20	3	M3121
Coexpression	GSE25087_FETAL_VS_ADULT_TCONV_UP	ZNF827 STIP1 PHACTR2	4.47e-04	199	20	3	M4645
Coexpression	GSE40685_TREG_VS_FOXP3_KO_TREG_PRECURSOR_UP	JADE2 CD2AP PIK3R3	4.47e-04	199	20	3	M9306
Coexpression	GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP	PHF2 PTK2 CD2AP	4.47e-04	199	20	3	M9255
Coexpression	HALLMARK_MITOTIC_SPINDLE	MYO1E SHROOM2 CD2AP	4.47e-04	199	20	3	M5893
Coexpression	GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	PHF2 ZNF827 GON4L	4.47e-04	199	20	3	M7524
Coexpression	GSE11057_CD4_EFF_MEM_VS_PBMC_UP	GON4L CD96 PHACTR2	4.47e-04	199	20	3	M3113
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN	FNBP4 STIP1 CD2AP	4.53e-04	200	20	3	M3981
Coexpression	GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	MYO1E FMNL1 CD96	4.53e-04	200	20	3	M7457
Coexpression	HALLMARK_APICAL_JUNCTION	SHROOM2 PTK2 PIK3R3	4.53e-04	200	20	3	M5915
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP	PHF2 FMNL1 PHACTR2	4.53e-04	200	20	3	M6524
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN	JADE2 PTK2 STIP1	4.53e-04	200	20	3	M5212
Coexpression	GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP	FNBP4 STIP1 PIK3R3	4.53e-04	200	20	3	M5261
ToppCell	PBMC-Severe-cDC_1\|Severe / Compartment, Disease Groups and Clusters	MYO1E PHF2 ZNF827	6.27e-06	81	20	3	6d1e524f000b71c935359afc801a1d31f218fec8
ToppCell	Monocytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	FMNL1 CMTM2 SYNPO2L	3.97e-05	150	20	3	b580b06795973fec16ea6f7f5b6b9d580bf7fcf5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E PHACTR2 CD2AP	5.66e-05	169	20	3	0332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell	facs-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96 RGL3	6.50e-05	177	20	3	9ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell	facs-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96 RGL3	6.50e-05	177	20	3	17065d37fd41f04f67282bee00365daa185e8355
ToppCell	facs-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96 RGL3	6.50e-05	177	20	3	6e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYO1E PTK2 PIK3R3	6.72e-05	179	20	3	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E PHACTR2 CD2AP	6.83e-05	180	20	3	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E ZNF827 CD2AP	6.94e-05	181	20	3	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MYO1E PTK2 PIK3R3	7.41e-05	185	20	3	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RGL3 PHACTR2 CD2AP	7.53e-05	186	20	3	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	normal_Lung-Myeloid_cells-pDCs\|normal_Lung / Location, Cell class and cell subclass	MYO1E PHF2 CD2AP	7.65e-05	187	20	3	d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SHROOM2 PTK2 PIK3R3	7.65e-05	187	20	3	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CD96 PHACTR2	8.14e-05	191	20	3	d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CD96 PHACTR2	8.14e-05	191	20	3	b42c54308abe1241cc38ddce96b9d38d07983891
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CD96 PHACTR2	8.14e-05	191	20	3	9aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SHROOM2 PTK2 PIK3R3	8.40e-05	193	20	3	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E RGL3 CD2AP	8.53e-05	194	20	3	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1E RGL3 CD2AP	8.53e-05	194	20	3	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF827 PTK2 CD2AP	8.53e-05	194	20	3	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	Sepsis-URO-Lymphocyte-T/NK-MAIT\|URO / Disease, condition lineage and cell class	ZNF827 CD96 PIK3R3	9.06e-05	198	20	3	75db638278d4be2b0f406cd8871058a8352c5a86
ToppCell	LPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_only / Treatment groups by lineage, cell group, cell type	MYO1E FMNL1 CD96	9.19e-05	199	20	3	b62a756b5472972156d05051a58671a58bef1f16
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD96 PHACTR2 CD2AP	9.19e-05	199	20	3	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO1E FMNL1 CD96	9.19e-05	199	20	3	c23a53a20487a8abfeb91fa5fc9c06823dd657e9
ToppCell	LPS_anti-TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYO1E FMNL1 CD96	9.19e-05	199	20	3	0986d4342dc61e623d0dfc9f9870af86f72a8be3
ToppCell	Sigmoid-T_cell-gd_T\|T_cell / Region, Cell class and subclass	MYO1E CD96 PIK3R3	9.33e-05	200	20	3	20844293c155d3f319ceeea9476979bc86515b53
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	JADE2 CD96 PIK3R3	9.33e-05	200	20	3	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	NS-control-d_0-4-Lymphoid-NKT\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FMNL1 CD96	4.97e-04	74	20	2	97f456f67a698bbf18418d20fc348dbb3f716889
ToppCell	control-Lymphoid-NKT\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FMNL1 CD96	7.51e-04	91	20	2	760780fd8f817de94c72ec4403ae9ad88978f2d9
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	TAF1L RGL3	1.19e-03	115	20	2	eae0227fbdffe41656d924d74dc885d7f5d5f73d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CD96 RGL3	1.28e-03	119	20	2	8eefcf1ace62ad1c90fa5b62ec159c83ec527bf3
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMNL1 CD96	1.74e-03	139	20	2	ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RGL3 CMTM2	1.81e-03	142	20	2	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RGL3 CMTM2	1.84e-03	143	20	2	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	control-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MYO1E GON4L	1.91e-03	146	20	2	69e9c1ec6eec1151290227902e75e77a4aecc8db
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1E RGL3	1.96e-03	148	20	2	fd0d8386b94adb1bdc993fbb44d2d87852bfd7f0
ToppCell	368C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CD96 PIK3R3	1.99e-03	149	20	2	9286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell	368C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CD96 PIK3R3	1.99e-03	149	20	2	f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCell	mild-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SHROOM2 CMTM2	2.02e-03	150	20	2	979566663d1110475f1e017c2f9890aca4b6f701
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ZNF827 CD96	2.04e-03	151	20	2	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SHROOM2 PHACTR2	2.04e-03	151	20	2	090b067873740c282865e2d02cf47d5cb3dd7607
ToppCell	Control-Lymphocytic_NKT-T_cells-iNKT-MAIT\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD96 CMTM2	2.04e-03	151	20	2	7e5e35ce601ca3d3722063566e89664909171b8d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	PHACTR2 SYNPO2L	2.04e-03	151	20	2	4533bccc996395f74b16af939ce79b6fe253c073
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	PHACTR2 SYNPO2L	2.04e-03	151	20	2	edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCell	PBMC-Severe-cDC_3\|Severe / Compartment, Disease Groups and Clusters	CMTM2 PIK3R3	2.07e-03	152	20	2	1a3f8ed476aa9a39742b4684be2c704669e4a3d0
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD96 PHACTR2	2.07e-03	152	20	2	405d19b290232bb3e564d61c0cff0cfdd247bdff
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CD96 PHACTR2	2.07e-03	152	20	2	06fa7d8acc8f56de00af9bee17884595b300410e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CD96 PHACTR2	2.10e-03	153	20	2	b101cb1bce5db785dab46b6c4f7be9c3efe48b0e
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_memory_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FNBP4 CD96	2.10e-03	153	20	2	64d0f37d7af9b76234f683379e3689771f71fe70
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-dn_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CD96 PHACTR2	2.10e-03	153	20	2	487388082bb596809ba1caf9197626b6814792ab
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 CMTM2	2.12e-03	154	20	2	1e32969bee810adaf2d560f0824a16227df513d8
ToppCell	COVID-19_Severe-Lymphoid_T/NK-dn_T\|COVID-19_Severe / Disease group, lineage and cell class	CD96 PHACTR2	2.18e-03	156	20	2	83f25683e0f55472b56f915ee176fc05efc33a31
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ENO4 JADE2	2.18e-03	156	20	2	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|Lung / Manually curated celltypes from each tissue	SHROOM2 CD96	2.21e-03	157	20	2	af6eb2214340847bbab7cb209ea27cdc83b62a27
ToppCell	severe_COVID-19-MAIT\|severe_COVID-19 / disease group, cell group and cell class (v2)	CD96 SYNPO2L	2.21e-03	157	20	2	175f637e9707836bd63b5c2ccc9d4eb601c05b9e
ToppCell	10x5'v1-week_12-13-Myeloid_DC-DC-tDC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MYO1E TAF1L	2.26e-03	159	20	2	141c3ed35c7d11fcaec4acd9cb37104cc259db25
ToppCell	droplet-Liver-LIVER_NPC-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96	2.26e-03	159	20	2	997963d879e5819683793cddf5e1acff1b81a1b8
ToppCell	droplet-Liver-LIVER_NPC\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96	2.26e-03	159	20	2	e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF827 CD96	2.29e-03	160	20	2	0f15f895f11dcabb73df79b26bfc4947f38435a7
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	JADE2 CD96	2.29e-03	160	20	2	8e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF827 CD96	2.29e-03	160	20	2	50d4f867d021abcfeb49e6812bcfd5bb57466a31
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF827 CD96	2.29e-03	160	20	2	7d004bfe42707605b3851cb2319126acda4d4802
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF827 CD96	2.32e-03	161	20	2	140b3c7077947c541cff54f6754e2df968345f4d
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FMNL1 CD96	2.32e-03	161	20	2	6d9907e2949a742c0933128fde57832a9ca5f77c
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96	2.35e-03	162	20	2	5731f9514434296132df4bc86f78ce87b07cdeca
ToppCell	367C-Lymphocytic-ILC-ILC-1\|367C / Donor, Lineage, Cell class and subclass (all cells)	ZNF827 CD96	2.35e-03	162	20	2	74cd0de957fdbe527656befd61f67d6814ce9e98
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96	2.35e-03	162	20	2	0321fc954ae4ad67ca438cbbc84632562d222188
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PHF2 PIK3R3	2.37e-03	163	20	2	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CMTM2	2.37e-03	163	20	2	57f02f2b9ce940a2962bb57cd8d02eb67b6f44a3
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD96 CMTM2	2.37e-03	163	20	2	004765e016c5658ee4a8bda4899804303064727b
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	MYO1E JADE2	2.37e-03	163	20	2	d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CMTM2	2.37e-03	163	20	2	155ac52a34e0d55545aab8a3e4162fc4c387e697
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNBP4 GON4L	2.37e-03	163	20	2	a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CMTM2	2.37e-03	163	20	2	c132fb5b56186a10d33ae5ce17b2a7e670d52f79
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD96 PHACTR2	2.40e-03	164	20	2	8f3255d7f67890389a768453492243ea982eb38a
ToppCell	URO-Lymphocyte-T_NK-MAIT\|URO / Disease, Lineage and Cell Type	ZNF827 PIK3R3	2.40e-03	164	20	2	cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CMTM2	2.40e-03	164	20	2	2c929996a19bbe29949010928001c277b5494a42
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL1 CD96	2.43e-03	165	20	2	6708beb0e8094f30cf5cd812e6a67a6db004a580
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL3 PTK2	2.43e-03	165	20	2	3d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	FMNL1 SYNPO2L	2.43e-03	165	20	2	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD2AP PIK3R3	2.46e-03	166	20	2	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FMNL1 CD96	2.46e-03	166	20	2	9fae71b0a42a9b2222453c03e0a1e83f30117ae9
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FMNL1 CD96	2.46e-03	166	20	2	fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CMTM2	2.46e-03	166	20	2	6a65dff1333f39ec8c584e6df04b8c1e7f1c8946
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD2AP PIK3R3	2.46e-03	166	20	2	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD96 PHACTR2	2.49e-03	167	20	2	9c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 CMTM2	2.49e-03	167	20	2	cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHROOM2 CD96	2.49e-03	167	20	2	92ddabbe55315856d8ea6f8db1560b6d97636bac
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CD96	2.52e-03	168	20	2	318fa1bd5a9d6ae95042517ef30515b6416b61e4
ToppCell	Immune_cells-NK_cells\|Immune_cells / Lineage and Cell class	JADE2 CD96	2.52e-03	168	20	2	125d70c37eb49eb4d1f503bb8d536b225254c7cb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CD96	2.52e-03	168	20	2	75b3998aff704a77895ee3723813d8a3819b7cec
ToppCell	PCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FMNL1 CD96	2.55e-03	169	20	2	45ac692a0c9064ce6b6a31c2cd21c85ccf594670
ToppCell	Control-T_cells-Tregs\|Control / group, cell type (main and fine annotations)	CD96 PHACTR2	2.55e-03	169	20	2	e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 CMTM2	2.55e-03	169	20	2	30141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FMNL1 CMTM2	2.55e-03	169	20	2	2e15a9317da4017757d184f7cc91bd66b072ac51
ToppCell	PCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_natural_killer_[NK]_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FMNL1 CD96	2.55e-03	169	20	2	3514a74980c7bd4bb76dbd06693f492e8dce21e0
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SHROOM2 RGL3	2.58e-03	170	20	2	4cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	SHROOM2 RGL3	2.58e-03	170	20	2	36c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PHACTR2 TAF1	2.58e-03	170	20	2	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like\|bone_marrow / Manually curated celltypes from each tissue	CD96 PHACTR2	2.61e-03	171	20	2	2977cffc146470733b5cfd8a1aa80d9346d4804d
Drug	Mfpa	TAF1L TAF1	2.20e-06	3	20	2	CID003035615
Drug	colcemid; Up 200; 11.7uM; MCF7; HT_HG-U133A_EA	PHF2 GON4L PTK2 PHACTR2	2.05e-05	190	20	4	1103_UP
Drug	Cyclopenthiazide [742-20-1]; Down 200; 10.6uM; PC3; HT_HG-U133A	MYO1E SHROOM2 GON4L TAF1	2.27e-05	195	20	4	4229_DN
Drug	F-dd	FNBP4 FMNL1 TAF1	4.73e-05	81	20	3	CID006102682
Drug	2-phenylindole	TAF1L TAF1	5.68e-05	13	20	2	CID000013698
Disease	left ventricular diastolic function measurement	MYO1E PTK2 SYNPO2L	6.46e-06	54	20	3	EFO_0008204
Disease	Focal segmental glomerulosclerosis	MYO1E CD2AP	1.96e-05	10	20	2	cv:C0017668
Disease	Inherited focal segmental glomerulosclerosis	MYO1E CD2AP	1.96e-05	10	20	2	cv:CN327126
Disease	Hereditary Nephrotic Syndromes, Autosomal Dominant	MYO1E CD2AP	2.39e-05	11	20	2	cv:CN043612
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	MYO1E CD2AP	3.39e-05	13	20	2	cv:C4273714
Disease	Hyalinosis, Segmental Glomerular	MYO1E CD2AP	1.63e-04	28	20	2	C0086432
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	MYO1E CD2AP	1.88e-04	30	20	2	C1868672
Disease	phosphatidylethanolamine measurement	MYO1E CD96 PHACTR2	2.10e-04	173	20	3	EFO_0010228
Disease	Focal glomerulosclerosis	MYO1E CD2AP	2.71e-04	36	20	2	C0017668
Disease	Metastatic melanoma	PTK2 TAF1	6.12e-04	54	20	2	C0278883
Disease	hearing loss	PTK2 PIK3R3	9.40e-04	67	20	2	EFO_0004238
Disease	Dupuytren Contracture	MYO1E PTK2	2.42e-03	108	20	2	EFO_0004229
Disease	Glioblastoma Multiforme	TAF1L PTK2	2.55e-03	111	20	2	C1621958
Disease	loneliness measurement	FNBP4 PHF2	3.17e-03	124	20	2	EFO_0007865
Disease	Paroxysmal atrial fibrillation	PTK2 SYNPO2L	4.96e-03	156	20	2	C0235480
Disease	Persistent atrial fibrillation	PTK2 SYNPO2L	4.96e-03	156	20	2	C2585653
Disease	familial atrial fibrillation	PTK2 SYNPO2L	4.96e-03	156	20	2	C3468561
Disease	Atrial Fibrillation	PTK2 SYNPO2L	5.21e-03	160	20	2	C0004238
Disease	cardioembolic stroke	PTK2 SYNPO2L	5.86e-03	170	20	2	EFO_1001976
Disease	heart failure	MYO1E SYNPO2L	6.90e-03	185	20	2	EFO_0003144
Disease	brain volume measurement	ENO4 GON4L PTK2	7.20e-03	595	20	3	EFO_0006930
Disease	health study participation	PHF2 JADE2	7.63e-03	195	20	2	EFO_0010130
Disease	neutrophil count, eosinophil count	MYO1E PIK3R3	9.05e-03	213	20	2	EFO_0004833, EFO_0004842
Disease	smoking behaviour measurement	JADE2 CD96	9.79e-03	222	20	2	EFO_0005671
Disease	monocyte count	MYO1E GON4L JADE2 STIP1	1.09e-02	1320	20	4	EFO_0005091

Protein segments in the cluster

Peptide	Gene	Start	Entry
PKPKKPPPPAKAPAP	CD2AP	336	Q9Y5K6
PAKKKPPPPPPQDGP	JADE2	601	Q9NQC1
PPSAPPKPRPKPKPK	PHACTR2	156	O75167
PMPPPPPPGVEIKKT	RGL3	116	Q3MIN7
EMDPPALPPKPPKPM	PIK3R3	31	Q92569
AEVVPMGPPPPPKPK	GON4L	441	Q3T8J9
APPPKQPAPPKQPMP	FMNL1	16	O95466
PPPPPPPPTKKKGQK	ENO4	196	A6NNW6
PPPMAPKTPPPMTPK	SYNPO2L	706	Q9H987
PMTPKTPPPVAPKPP	SYNPO2L	716	Q9H987
KPSKIPKPPKPPKPP	PHF2	501	O75151
PPPPPKKETKPEPME	STIP1	201	P31948
PPPAPKMPPPEKTKK	FNBP4	916	Q8N3X1
PPPPPPPGPMKKDKD	TAF1L	156	Q8IZX4
MPPPPPPPGPMKKDK	TAF1	156	P21675
KPDPAAPPKKPPRPG	PTK2	866	Q05397
DKKKAPSSPPPPPPP	SHROOM2	306	Q13796
PAKPPEPGKPPGPAK	CMTM2	231	Q8TAZ6
MERPPPFKPPPPPIK	CD96	551	P40200
EKKPEKVTPPPPPPP	ZNF827	321	Q17R98
PPPAGGRPKPQPKPK	MYO1E	1036	Q12965