Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionplatelet-derived growth factor binding

PDGFA PDGFB

4.15e-0412512GO:0048407
GeneOntologyMolecularFunctiontranscription coregulator activity

BHLHE41 BRCA1 RRP1B KAT6A AEBP2 TACC1 SFMBT2

5.33e-04562517GO:0003712
GeneOntologyMolecularFunctionC2H2 zinc finger domain binding

GATA2 EHMT1

8.49e-0417512GO:0070742
GeneOntologyMolecularFunctionplatelet-derived growth factor receptor binding

PDGFA PDGFB

8.49e-0417512GO:0005161
GeneOntologyBiologicalProcessnegative regulation of phosphatidylinositol biosynthetic process

PDGFA PDGFB

5.76e-062502GO:0010512
GeneOntologyBiologicalProcesspositive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

PDGFA PDGFB

1.73e-053502GO:0035793
GeneOntologyBiologicalProcessregulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

PDGFA PDGFB

1.73e-053502GO:1900238
GeneOntologyBiologicalProcesspositive regulation of metanephric mesenchymal cell migration

PDGFA PDGFB

1.73e-053502GO:2000591
GeneOntologyBiologicalProcessmetanephric mesenchymal cell migration

PDGFA PDGFB

3.44e-054502GO:0035789
GeneOntologyBiologicalProcessregulation of metanephric mesenchymal cell migration

PDGFA PDGFB

3.44e-054502GO:2000589
GeneOntologyBiologicalProcesscell migration involved in metanephros development

PDGFA PDGFB

5.73e-055502GO:0035788
GeneOntologyBiologicalProcessregulation of phosphatidylinositol biosynthetic process

PDGFA PDGFB

5.73e-055502GO:0010511
GeneOntologyBiologicalProcessregulation of DNA metabolic process

FOXM1 NUGGC PARP4 BRCA1 PDGFA PDGFB DPF3 INO80E

5.80e-05564508GO:0051052
GeneOntologyBiologicalProcessnegative regulation of phospholipid biosynthetic process

PDGFA PDGFB

8.59e-056502GO:0071072
GeneOntologyBiologicalProcesscell migration involved in kidney development

PDGFA PDGFB

8.59e-056502GO:0035787
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

FOXM1 BHLHE41 SP100 ZNF274 BRCA1 PDGFB KAT6A GATA2 AEBP2 EHMT1 SOX18 SFMBT2

9.81e-0513995012GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

FOXM1 BHLHE41 SP100 ZNF274 BRCA1 PDGFB KAT6A GATA2 AEBP2 EHMT1 SOX18 SFMBT2

1.08e-0414135012GO:1902679
GeneOntologyBiologicalProcessnegative regulation of phospholipid metabolic process

PDGFA PDGFB

1.20e-047502GO:1903726
GeneOntologyBiologicalProcesschromatin organization

ZNF274 BRCA1 DPF3 KAT6A AEBP2 EHMT1 UTP3 KDM4B INO80E

2.67e-04896509GO:0006325
GeneOntologyBiologicalProcesspositive regulation of DNA repair

FOXM1 BRCA1 DPF3 INO80E

3.98e-04143504GO:0045739
GeneOntologyBiologicalProcessregulation of glomerular mesangial cell proliferation

PDGFA PDGFB

5.14e-0414502GO:0072124
GeneOntologyBiologicalProcessprotein-DNA complex organization

ZNF274 BRCA1 DPF3 KAT6A AEBP2 EHMT1 UTP3 KDM4B INO80E

5.90e-04999509GO:0071824
GeneOntologyBiologicalProcessglomerular mesangial cell proliferation

PDGFA PDGFB

5.93e-0415502GO:0072110
GeneOntologyBiologicalProcessplatelet-derived growth factor receptor-beta signaling pathway

PDGFA PDGFB

5.93e-0415502GO:0035791
GeneOntologyCellularComponentplatelet-derived growth factor complex

PDGFA PDGFB

6.31e-062532GO:1990265
GeneOntologyCellularComponentgrowth factor complex

PDGFA PDGFB

1.75e-048532GO:0036454
DomainNPIP

NPIPB8 NPIPB15 NPIPB9 NPIPB6

6.59e-0814554IPR009443
DomainPDGF_N

PDGFA PDGFB

8.51e-062552IPR006782
DomainPDGF_N

PDGFA PDGFB

8.51e-062552PF04692
DomainPHD

DPF3 KAT6A KDM4B SP140

7.00e-0575554PF00628
DomainHSR

SP100 SP140

8.47e-055552PS51414
DomainHSR

SP100 SP140

8.47e-055552PF03172
DomainHSR_dom

SP100 SP140

8.47e-055552IPR004865
DomainPHD

DPF3 KAT6A KDM4B SP140

1.36e-0489554SM00249
DomainZnf_PHD

DPF3 KAT6A KDM4B SP140

1.49e-0491554IPR001965
DomainZF_PHD_2

DPF3 KAT6A KDM4B SP140

1.76e-0495554PS50016
DomainPD_growth_factor_CS

PDGFA PDGFB

1.77e-047552IPR023581
DomainZF_PHD_1

DPF3 KAT6A KDM4B SP140

1.83e-0496554PS01359
DomainSAND_dom

SP100 SP140

2.36e-048552IPR000770
DomainSAND

SP100 SP140

2.36e-048552PF01342
DomainSAND

SP100 SP140

2.36e-048552PS50864
DomainSAND

SP100 SP140

2.36e-048552SM00258
DomainPDGF

PDGFA PDGFB

3.02e-049552PF00341
DomainPDGF_2

PDGFA PDGFB

3.02e-049552PS50278
DomainPDGF_1

PDGFA PDGFB

3.02e-049552PS00249
DomainPDGF/VEGF_dom

PDGFA PDGFB

3.02e-049552IPR000072
DomainPDGF

PDGFA PDGFB

3.02e-049552SM00141
Domain-

SP100 SP140

5.51e-04125523.10.390.10
DomainSAND_dom-like

SP100 SP140

5.51e-0412552IPR010919
DomainZnf_FYVE_PHD

DPF3 KAT6A KDM4B SP140

9.20e-04147554IPR011011
DomainBRCT

PARP4 BRCA1

1.41e-0319552PF00533
DomainZnf_PHD-finger

DPF3 KAT6A SP140

1.63e-0379553IPR019787
DomainBRCT

PARP4 BRCA1

1.89e-0322552SM00292
DomainADAM_spacer1

ADAMTS20 ADAMTS14

2.07e-0323552IPR010294
DomainADAM_spacer1

ADAMTS20 ADAMTS14

2.07e-0323552PF05986
Domain-

PARP4 BRCA1

2.07e-03235523.40.50.10190
DomainPeptidase_M12B_ADAM-TS

ADAMTS20 ADAMTS14

2.25e-0324552IPR013273
DomainBRCT

PARP4 BRCA1

2.64e-0326552PS50172
DomainBRCT_dom

PARP4 BRCA1

3.06e-0328552IPR001357
DomainPeptidase_M12B_N

ADAMTS20 ADAMTS14

5.88e-0339552IPR002870
DomainPep_M12B_propep

ADAMTS20 ADAMTS14

5.88e-0339552PF01562
DomainDISINTEGRIN_1

ADAMTS20 ADAMTS14

6.18e-0340552PS00427
DomainReprolysin

ADAMTS20 ADAMTS14

6.18e-0340552PF01421
DomainADAM_MEPRO

ADAMTS20 ADAMTS14

6.18e-0340552PS50215
DomainDISINTEGRIN_2

ADAMTS20 ADAMTS14

6.18e-0340552PS50214
DomainPeptidase_M12B

ADAMTS20 ADAMTS14

6.18e-0340552IPR001590
DomainDisintegrin_dom

ADAMTS20 ADAMTS14

6.49e-0341552IPR001762
DomainSAM_2

PPFIA4 SFMBT2

7.12e-0343552PF07647
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

DPF3 KAT6A AEBP2 EHMT1 KDM4B INO80E

2.07e-0715756630186101
Pubmed

Evidence that the v-sis gene product transforms by interaction with the receptor for platelet-derived growth factor.

PDGFA PDGFB

2.55e-0625622996133
Pubmed

Collagen-induced binding to human platelets of platelet-derived growth factor leading to inhibition of P43 and P20 phosphorylation.

PDGFA PDGFB

2.55e-0625622538439
Pubmed

FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway.

FOXM1 PDGFA

2.55e-06256225869208
Pubmed

Expression of platelet-derived growth factor-A (PDGF-A), PDGF-B, and PDGF receptor-alpha and -beta during human testicular development and disease.

PDGFA PDGFB

2.55e-06256211994382
Pubmed

Platelet-derived growth factor.

PDGFA PDGFB

2.55e-0625627640655
Pubmed

Platelet-derived growth factor beta-receptors can both promote and inhibit chemotaxis in human vascular smooth muscle cells.

PDGFA PDGFB

2.55e-0625629409235
Pubmed

Endothelial-perivascular cell signaling in vascular development: lessons from knockout mice.

PDGFA PDGFB

2.55e-0625629812194
Pubmed

LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.

SP100 SP140

2.55e-0625628695863
Pubmed

Characterization of the mouse PDGF A-chain gene. Evolutionary conservation of gene structure, nucleotide sequence and alternative splicing.

PDGFA PDGFB

2.55e-0625621340209
Pubmed

Assignment of interchain disulfide bonds in platelet-derived growth factor (PDGF) and evidence for agonist activity of monomeric PDGF.

PDGFA PDGFB

2.55e-0625621317862
Pubmed

Lyophilised Platelet-Rich Fibrin: Physical and Biological Characterisation.

PDGFA PDGFB

2.55e-06256234885714
Pubmed

Platelet-derived growth factor-AB promotes the generation of adult bone marrow-derived cardiac myocytes.

PDGFA PDGFB

2.55e-06256214963008
Pubmed

A common PDGF receptor is activated by homodimeric A and B forms of PDGF.

PDGFA PDGFB

2.55e-0625622836953
Pubmed

Retina-specific expression of PDGF-B versus PDGF-A: vascular versus nonvascular proliferative retinopathy.

PDGFA PDGFB

2.55e-06256212037011
Pubmed

Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells.

PDGFA PDGFB

2.55e-06256211788434
Pubmed

Purification of human platelet-derived growth factor.

PDGFA PDGFB

2.55e-062562287022
Pubmed

Platelet-derived growth factor receptors and ligands are up-regulated in paediatric fibromatoses.

PDGFA PDGFB

2.55e-06256217944929
Pubmed

Viability of transgenic mice expressing a platelet derived growth factor (PDGF) antagonist in plasma.

PDGFA PDGFB

2.55e-0625628689409
Pubmed

PDGF induces c-myc mRNA expression in MG-63 human osteosarcoma cells but does not stimulate cell replication.

PDGFA PDGFB

2.55e-0625622439522
Pubmed

Emphysematous lesions, inflammation, and fibrosis in the lungs of transgenic mice overexpressing platelet-derived growth factor.

PDGFA PDGFB

2.55e-06256210362801
Pubmed

Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells.

PDGFA PDGFB

2.55e-06256214997209
Pubmed

Glycation of PDGF results in decreased biological activity.

PDGFA PDGFB

2.55e-06256220083221
Pubmed

Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains.

PDGFA PDGFB

2.55e-06256212615918
Pubmed

Platelet-derived growth factor: identification of constituent polypeptide chains.

PDGFA PDGFB

2.55e-0625627073684
Pubmed

Platelet-derived growth factor: purification and partial characterization.

PDGFA PDGFB

2.55e-062562291037
Pubmed

Developmental distribution of platelet-derived growth factor in the mouse central nervous system.

PDGFA PDGFB

7.63e-0635621324805
Pubmed

Expression of platelet-derived growth factor ligand and receptor in cerebral arteriovenous and cavernous malformations.

PDGFA PDGFB

7.63e-06356220822908
Pubmed

Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha.

PDGFA PDGFB

7.63e-06356233168840
Pubmed

PDGF and bFGF modulate tube formation in adipose tissue-derived stem cells.

PDGFA PDGFB

7.63e-06356220224347
Pubmed

PDGF receptor signaling networks in normal and cancer cells.

PDGFA PDGFB

7.63e-06356224703957
Pubmed

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors.

PDGFA PDGFB

7.63e-0635621311092
Pubmed

Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor.

PDGFA PDGFB

7.63e-0635626093261
Pubmed

The increased PDGF-A, PDGF-B and FGF-2 expression in recurrence of salivary gland pleomorphic adenoma.

PDGFA PDGFB

7.63e-06356222174424
Pubmed

Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved.

PDGFA PDGFB

7.63e-06356219998489
Pubmed

A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.

PDGFA PDGFB

7.63e-06356219956642
Pubmed

PDGF suppresses oxidative stress induced Ca2+ overload and calpain activation in neurons.

PDGFA PDGFB

7.63e-06356224454980
Pubmed

Time- and pH-dependent release of PDGF and TGF-beta from platelets in vitro.

PDGFA PDGFB

7.63e-06356212850832
Pubmed

Urokinase potentiates PDGF-induced chemotaxis of human airway smooth muscle cells.

PDGFA PDGFB

7.63e-06356212576295
Pubmed

FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells.

FOXM1 PDGFA

7.63e-06356225832656
Pubmed

Regulation of PDGF and PDGF receptor in cultured dermal papilla cells and follicular keratinocytes of the human hair follicle.

PDGFA PDGFB

7.63e-06356214705808
Pubmed

Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: implications as a potential therapeutic target.

PDGFA PDGFB

7.63e-06356215767546
Pubmed

The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization.

PDGFA PDGFB

7.63e-06356212176888
Pubmed

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

PDGFA PDGFB

7.63e-0635622544881
Pubmed

Muscarinic modulation of Cav2.3 (R-type) calcium channels is antagonized by RGS3 and RGS3T.

CACNA1E RGS3

7.63e-06356216855219
Pubmed

Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells.

PDGFA PDGFB

7.63e-06356217958740
Pubmed

PDGF receptor-{beta} modulates metanephric mesenchyme chemotaxis induced by PDGF AA.

PDGFA PDGFB

7.63e-06356219019919
Pubmed

Mapping of the binding of platelet-derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope.

PDGFA PDGFB

7.63e-0635629692901
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SP100 BRCA1 DPF3 BTBD18 KAT6A EHMT1 PCMTD1 DNTTIP2 SP140 INO80E

1.04e-051116561031753913
Pubmed

Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.

FOXM1 PDGFA PDGFB

1.13e-052756325631042
Pubmed

Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell.

PDGFA PDGFB

1.52e-05456212070119
Pubmed

Platelet-derived growth factors (PDGF-A and -B) and their receptors in human fetal and adult ovaries.

PDGFA PDGFB

1.52e-05456218326546
Pubmed

The role of platelet-derived growth factor in the development of mouse molars.

PDGFA PDGFB

1.52e-0545628901196
Pubmed

Urokinase-type plasminogen activator receptor interaction with β1 integrin is required for platelet-derived growth factor-AB-induced human mesenchymal stem/stromal cell migration.

PDGFA PDGFB

1.52e-05456226420039
Pubmed

Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates.

PDGFA PDGFB

1.52e-05456212411321
Pubmed

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

PDGFA PDGFB

1.52e-0545627958864
Pubmed

The function of platelet-derived growth factor in the differentiation of mouse tongue striated muscle.

PDGFA PDGFB

1.52e-05456222264326
Pubmed

Expression of platelet-derived growth factor and its receptors in the developing and adult mouse kidney.

PDGFA PDGFB

1.52e-0545629734598
Pubmed

Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes.

PDGFA PDGFB

1.52e-0545622536956
Pubmed

The distribution of PDGFs and PDGF-receptors during murine secondary palate development.

PDGFA PDGFB

1.52e-0545627649812
Pubmed

The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions.

PDGFA PDGFB

1.52e-05456211239463
Pubmed

Characterization of a novel platelet-derived growth factor-associated protein.

PDGFA PDGFB

1.52e-0545628780057
Pubmed

Signal transduction via platelet-derived growth factor receptors.

PDGFA PDGFB

1.52e-0545629739761
Pubmed

PDGF: the nuts and bolts of signalling toolbox.

PDGFA PDGFB

1.52e-05456221769672
Pubmed

Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor.

PDGFA PDGFB

1.52e-0545627679113
Pubmed

Expression of platelet-derived growth factor (PDGF) in the epididymis and analysis of the epididymal development in PDGF-A, PDGF-B, and PDGF receptor beta deficient mice.

PDGFA PDGFB

1.52e-05456214522834
Pubmed

Selective expression of PDGF A and its receptor during early mouse embryogenesis.

PDGFA PDGFB

1.52e-0545622155144
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SP100 RRP1B RRP12 UTP3 RBM28 DNTTIP2

1.57e-0533256625693804
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1E SP100 BRCA1 PDGFA SUSD1 PPFIA4 CCNO CAGE1 RPL4 SFMBT2 DNTTIP2

1.60e-051442561135575683
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

FOXM1 BRCA1 RRP1B RRP12 ELAC2 DNTTIP2

1.77e-0533956630415952
Pubmed

Directed proteomic analysis of the human nucleolus.

RRP1B RRP12 UTP3 RBM28 RPL4

2.17e-0520856511790298
Pubmed

Mapping growth-factor-modulated Akt signaling dynamics.

PDGFA PDGFB

2.54e-05556227044757
Pubmed

PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor.

PDGFA PDGFB

2.54e-05556210806482
Pubmed

Low concentration of PDGF-AB shows synergism with IFN-α in induction of IFN-β and -γ in MRC5 fibroblasts.

PDGFA PDGFB

2.54e-05556224063997
Pubmed

Normal reproductive and macrophage function in Pem homeobox gene-deficient mice.

GATA2 NOS2

2.54e-0555629769172
Pubmed

Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta.

PDGFA PDGFB

2.54e-05556210681572
Pubmed

Obstructive uropathy in mice and humans: potential role for PDGF-D in the progression of tubulointerstitial injury.

PDGFA PDGFB

2.54e-05556214514732
Pubmed

Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.

PDGFA PDGFB

2.54e-05556220534510
Pubmed

PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta.

PDGFA PDGFB

2.54e-05556210419690
Pubmed

Immunohistochemical localization of growth factors in fetal wound healing.

PDGFA PDGFB

2.54e-0555621879607
Pubmed

Coordinate regulation by diethylstilbestrol of the platelet-derived growth factor-A (PDGF-A) and -B chains and the PDGF receptor alpha- and beta-subunits in the mouse uterus and vagina: potential mediators of estrogen action.

PDGFA PDGFB

2.54e-0555627720681
Pubmed

Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2.

BRCA1 TACC1

2.54e-05556219176389
Pubmed

PDGFs and their receptors.

PDGFA PDGFB

3.80e-05656228267575
Pubmed

Role of platelet-derived growth factor-AB in tumour growth and angiogenesis in relation with other angiogenic cytokines in multiple myeloma.

PDGFA PDGFB

3.80e-05656221919032
Pubmed

IRS1-independent defects define major nodes of insulin resistance.

PDGFA PDGFB

3.80e-05656218460333
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

RRP1B RRP12 UTP3 RBM28 RPL4

4.75e-0524556521182205
Pubmed

Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development.

PDGFA PDGFB

5.32e-0575629374392
Pubmed

PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice.

PDGFA PDGFB

5.32e-05756227816607
Pubmed

Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation.

PDGFA PDGFB

5.32e-0575627588258
Pubmed

Platelet-derived growth factor signals play critical roles in differentiation of longitudinal smooth muscle cells in mouse embryonic gut.

PDGFA PDGFB

7.09e-05856218194151
Pubmed

Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain.

PDGFA PDGFB

7.09e-0585628647855
Pubmed

Lens-specific expression of PDGF-A alters lens growth and development.

PDGFA PDGFB

7.09e-0585628954727
Pubmed

Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad.

PDGFA PDGFB

7.09e-05856212651897
Pubmed

Mesenchymal stem cells produce Wnt isoforms and TGF-beta1 that mediate proliferation and procollagen expression by lung fibroblasts.

PDGFA PDGFB

9.10e-05956219734317
Pubmed

Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB).

PDGFA PDGFB

9.10e-0595628900172
Pubmed

Role and regulation of PDGFRα signaling in liver development and regeneration.

PDGFA PDGFB

9.10e-05956223529017
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

RRP1B RRP12 UTP3 DNTTIP2

9.74e-0514856432538781
Pubmed

New nomenclature for chromatin-modifying enzymes.

KAT6A EHMT1 KDM4B

1.09e-045756318022353
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

RRP1B RRP12 UTP3 RBM28 RPL4 DNTTIP2

1.25e-0448356636912080
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

RRP1B RRP12 AVPI1 SSR1 UTP3 RBM28 RPL4 DNTTIP2

1.33e-0494956836574265
InteractionRPS24 interactions

BRCA1 RRP1B RRP12 KAT6A GATA2 UTP3 RBM28 RPL4 DNTTIP2

1.03e-05529549int:RPS24
InteractionDNAJC9 interactions

FOXM1 RRP1B RRP12 KAT6A EHMT1 RBM28 DNTTIP2

1.35e-05296547int:DNAJC9
InteractionRPL23A interactions

SP100 BRCA1 RRP1B RRP12 KAT6A SSR1 UTP3 RBM28 RPL4

3.01e-05606549int:RPL23A
InteractionPOLR1G interactions

RRP1B RRP12 KAT6A EHMT1 UTP3 RBM28 RPL4 DNTTIP2

4.43e-05489548int:POLR1G
InteractionRPS19 interactions

SP100 BRCA1 RRP1B RRP12 KAT6A EHMT1 UTP3 RBM28 RPL4

4.55e-05639549int:RPS19
InteractionH1-2 interactions

SP100 RRP12 KAT6A AEBP2 CCNO XRRA1 UTP3 DNTTIP2 SP140

6.26e-05666549int:H1-2
InteractionRPL31 interactions

BRCA1 RRP1B RRP12 KAT6A UTP3 RBM28 NOS2 RPL4 DNTTIP2

7.34e-05680549int:RPL31
InteractionPDGFB interactions

PDGFB RRP12 UTP3 RBM28

9.09e-0588544int:PDGFB
InteractionNHLH1 interactions

RRP1B EHMT1 RBM28 INO80E

9.09e-0588544int:NHLH1
Cytoband16p11.2

NPIPB8 NPIPB7 NPIPB6 INO80E

9.00e-0519156416p11.2
Cytoband6p24.3

CAGE1 SSR1

3.32e-04225626p24.3
CytobandEnsembl 112 genes in cytogenetic band chr12p12

BHLHE41 PDE3A AEBP2

3.66e-04113563chr12p12
CytobandEnsembl 112 genes in cytogenetic band chr9q32

SUSD1 RGS3

1.72e-0350562chr9q32
Cytoband2q37.1

SP100 SP140

3.07e-03675622q37.1
CytobandEnsembl 112 genes in cytogenetic band chr6p24

CAGE1 SSR1

3.35e-0370562chr6p24
CytobandEnsembl 112 genes in cytogenetic band chr16p11

NPIPB8 NPIPB9 INO80E

4.81e-03278563chr16p11
GeneFamilyPHD finger proteins

SP100 DPF3 KAT6A SP140

2.99e-059036488
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS20 ADAMTS14

6.45e-041936250
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF274 GATA2 ARHGAP9 RGS3 SP140

1.71e-061595659f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BHLHE41 SP100 SUSD1 ARHGAP9 CRAMP1

2.05e-0616556566f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB GATA2 SOX18 NOS2 RGS3

3.78e-0618756525efb82afe863a853ecdd781ad89026c993aaa67
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A GATA2 SOX18 AVPI1 RGS3

3.78e-0618756566ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A GATA2 SOX18 AVPI1 RGS3

3.88e-061885655bc1537e079c7435196c163bff5f639ea392a33a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Myeloid-Microglia|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 SP100 PDGFB ARHGAP9 SFMBT2

5.00e-06198565c0d33629438504a1545e07f0e5af2e76f50fd55b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Myeloid|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 SP100 PDGFB ARHGAP9 SFMBT2

5.00e-061985652b93995f66c7352acc25d6c71d025b847881dacd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-BMP_responsible_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 SP100 PDGFB ARHGAP9 SFMBT2

5.25e-06200565cd0d69f973ca3204b500d12031b403a1f4593431
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 SP100 PDGFB ARHGAP9 SFMBT2

5.25e-0620056516caefcc5bdca82d904462c6fd0ffa80d96fa474
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SP100 SOX18 NOS2 SP140

2.24e-05131564308ddb7fe113eac5dbeb9cb0b688d9e09275ce5e
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

SP100 GATA2 SOX18 NOS2

2.83e-0513956434398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

SP100 GATA2 SOX18 NOS2

2.83e-05139564450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPF3 SOX18 ARHGAP9 XRRA1

3.91e-051515647270b8bbfae659e110bd9d513b602120b25de3dd
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK|Thalamus / BrainAtlas - Mouse McCarroll V32

SP100 GATA2 SOX18 SP140

4.33e-05155564fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDE3A GATA2 SOX18 RGS3

4.55e-05157564275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A RRP1B RRP12 ARHGAP9

4.55e-05157564f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP9 CAGE1 ADAMTS14 RGS3

4.90e-05160564398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-naive_B_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SP100 CAGE1 KDM4B SP140

4.90e-05160564bfbac5ed3273b4430314c6c25cdc1bf0c42b27a1
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP9 CAGE1 ADAMTS14 RGS3

4.90e-0516056412aaab0291035f578e2433efd169ae72f393a5a5
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE3A NPIPB15 RRP12 GATA2

5.02e-051615641f4614ae15bd2fc08e555cea4d0152c4a940d048
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3A NPIPB15 GATA2 JAKMIP2

5.27e-05163564e4077e587895c85bc806be05ff5d451088e39468
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PARP4 GATA2 ADAMTS14 JAKMIP2

5.39e-051645642c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E CTSE SP140

5.52e-0516556436415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E CTSE SP140

5.52e-0516556456310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E SP100 SUSD1 SP140

5.65e-051665643e3e9296e6919a38602e417a6606c046af3bd101
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E NUGGC CTSE SP140

5.92e-0516856441da200bbff5c663c39f67c38d6d5f43b0ad9494
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BHLHE41 SP100 RPL4 SP140

5.92e-05168564943687a33fffd7e19d906b9dd385a126bcea109a
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E NUGGC CTSE SP140

5.92e-05168564a77259c13508f19186d7b0f80b34dc6d89497ab5
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

PARP4 PDE3A GATA2 JAKMIP2

6.20e-05170564e90f18e5462381b38e918442b38b1c8105291908
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

BHLHE41 NUGGC SFMBT2 SP140

6.34e-05171564a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 SP100 ADAMTS14 PCMTD1

6.49e-05172564910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E SP100 SP140

6.78e-0517456428ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDGFB GATA2 SOX18 NOS2

6.78e-05174564b1bcd5f4505d2ccef4183fcfbf1de81964b3f9e0
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTBD18 GATA2 SOX18 NOS2

7.09e-051765645386386619cf173939d3c117b20e6f27ab397993
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E NUGGC SP140

7.09e-0517656435610e7ac9902687e222641202409bab279c3998
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E SP100 SP140

7.09e-05176564741fdacb33d49b030a797a6099fdea0949a22e75
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BHLHE41 CACNA1E CTSE SP140

7.09e-05176564318dc722b95e269002fb01a0feb91c0c8539e150
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BTBD18 GATA2 SOX18 NOS2

7.09e-05176564820edade963768e4bfd86b554da4cd7100567ac8
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDE3A TMC1 GATA2 SOX18

7.09e-0517656452af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellfacs-Trachea-24m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BHLHE41 CACNA1E CTSE SP140

7.09e-05176564f6891006d816309edabe75b2abf60675f2958e55
ToppCellfacs-GAT-Fat-24m-Lymphocytic-B_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E CTSE SP140

7.25e-05177564f4afe10522eed77318954210224496f09d372532
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BHLHE41 SP100 RPL4 SP140

7.25e-05177564c506b8fd9a550e6cf93b64a1f7eed2543224a140
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BHLHE41 SP100 RPL4 SP140

7.25e-05177564840eaac045ada42cae0ab81177d1d0ae55a65633
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NUGGC NPIPB15 NPIPB9

7.25e-05177564d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NUGGC NPIPB15 NPIPB9

7.25e-0517756465e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC PDGFB GATA2 SOX18

7.25e-051775642433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMC1 PDGFB SOX18 TACC1

7.41e-05178564375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 SPHKAP ANKRD23 CTSE

7.57e-051795644135f9e8cd8494cbc189e5210dded84659643fb8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BHLHE41 SP100 RPL4 SP140

7.74e-05180564b83d067dee641941c596e4a25d81327931b6ad61
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NPIPB9 CAGE1 ELAC2

7.74e-051805648e96f8646c002768b272359af485dc0ab57e0ccd
ToppCellfacs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC PDGFB GATA2 SOX18

7.74e-05180564082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC PDGFB GATA2 SOX18

7.74e-0518056453043d764fad9ac33ee40e356e562e759931adef
ToppCellNS-moderate-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARHGAP9 JAKMIP2 SFMBT2 SP140

7.90e-051815647fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB GATA2 SOX18 RGS3

7.90e-051815649bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NUGGC ARHGAP9 SFMBT2 SP140

7.90e-051815646cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NUGGC ARHGAP9 SFMBT2 SP140

7.90e-05181564b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E CTSE SP140

7.90e-0518156414faef1dde781d501834379f2a6413e8d6a80b72
ToppCelldroplet-Heart-nan-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 RGS3

7.90e-05181564859c40889ede2cbf374c4d2efbb72dc3bc6441f5
ToppCellPND10-Immune|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SP100 ARHGAP9 RPL4 SP140

7.90e-05181564ef424f7eefe1b190a2be2ebcae7652eb8e7ba883
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB GATA2 SOX18 RGS3

8.07e-051825640346f81bbb1f309f3e9d063b20547d548d09472c
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SP100 ARHGAP9 RPL4 SP140

8.25e-05183564f929c4a42855313641008385f4e785e2a1c5a139
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E NUGGC CTSE

8.25e-05183564edb0069c66b1465dcc0bb5881417c6b17184fd74
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CTSE RPL4 SP140

8.25e-051835641614704fe0d8cd4c54c49f93f0cefb790ca897c7
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE41 CACNA1E NUGGC SP140

8.42e-0518456482d2daa39e3c31a74c08a5d77366740b87beb2fb
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXM1 BRCA1 DPF3 PPFIA4

8.42e-051845648260e688ec42a1374727bc85dceb7edd19a8b662
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BHLHE41 CACNA1E SP100 SP140

8.60e-051855645fd4a3776259c96cf2dcb87f050af8226acbbda9
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 RGS3

8.60e-05185564512a195ebbae445afe3722a3943020080daf2f3c
ToppCelldroplet-Heart-nan-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

8.60e-0518556411a44006950f6ccade86a85d5f06696d2036ffde
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB SUSD1 SOX18 RGS3

8.60e-05185564602536a3308a848f106adcb0a83530997440c8f4
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BHLHE41 CACNA1E SP100 SP140

8.60e-051855644c55fa96877ab9a00fcbec3fb70fd2208d222527
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDGFA PDGFB GATA2 RGS3

8.60e-05185564698ff44fd2d9b3ad5cea45f4cff9bfc64c559b62
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

8.78e-05186564f8ed078684ce6d914fd9cb1f0ef4aba36db39b3f
ToppCelldroplet-Heart-nan-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

8.78e-051865648b316bfed39b91c15d5ae28d9261eb057f113796
ToppCellfacs-Heart-LA-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

8.78e-051865641d08e60d239153c9e5ea42135d702d494d8b42b1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 PDGFB GATA2 SOX18

8.78e-05186564ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellwk_20-22-Hematologic_Lymphocytic-B-CD5+_CCL22-_mature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SP100 ARHGAP9 KDM4B SP140

8.78e-051865643941d4af5f2b209d71f59d7d920f2322131b4a0c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 PDGFB GATA2 SOX18

8.78e-0518656465e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDGFA PDGFB GATA2 RGS3

8.78e-05186564981116561986f94e9cc3ee64fb37dab9a31d427a
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA2 SOX18 AVPI1 RGS3

8.78e-051865645302399825f213d105ac70b91366a4513b732838
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 PDGFB GATA2 SOX18

8.78e-05186564e4f1259725160719e5fd13d76e5a707efed70013
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NUGGC NPIPB15 NPIPB9

8.96e-0518756488d20f150df61ef0e3ee0c3e9895b094920c4b09
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NUGGC NPIPB15 NPIPB9

8.96e-05187564158c2c003fd225ba61793fb06eece232fb063d05
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB GATA2 SOX18 RGS3

8.96e-05187564d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PDGFB GATA2 SOX18 RGS3

9.15e-05188564366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

9.15e-05188564ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 CACNA1E NUGGC NPIPB9

9.15e-05188564ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCell15-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

BHLHE41 PDE3A TACC1 RGS3

9.15e-051885644963382e54aac06bf5047c7d725393db70667ee7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 PDGFB GATA2 SOX18

9.15e-051885644dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

9.15e-05188564e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 PDGFB GATA2 SOX18

9.15e-05188564d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 PDGFB GATA2 SOX18

9.15e-051885641e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

9.15e-051885640fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E PDE3A GATA2 RGS3

9.34e-051895648e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellPND07-28-samps-Endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PDE3A PDGFB GATA2 SOX18

9.34e-05189564eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB GATA2 SOX18 RGS3

9.34e-051895649e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCellnormal-na-Lymphocytic_B-B_plasma|normal / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NUGGC NPIPB15 NPIPB9

9.34e-05189564659deb617a560bcde67c75f477d30ce85aaec3c6
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E PDE3A GATA2 RGS3

9.34e-05189564fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PDE3A PDGFB GATA2 SOX18

9.34e-05189564d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCellnormal-na-Lymphocytic_B-B_plasma-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

BHLHE41 NUGGC NPIPB15 NPIPB9

9.34e-0518956467f9a9861d2dcc128b7a69432c6b31da185e2249
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB GATA2 SOX18 NOS2

9.53e-0519056489d1d686cc683206534e2157554d7d0df5d53497
DrugPizotifen malate [5189-11-7]; Up 200; 9.4uM; PC3; HT_HG-U133A

PDGFA PDGFB EHMT1 CCNO CTSE KDM4B

4.96e-061855465072_UP
Drugpeonidin

PDGFA PDGFB

5.52e-062542ctd:C473205
DrugUrosiol [128-13-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A

BRCA1 PDGFA PDGFB RRP1B CCNO JAKMIP2

7.75e-062005466484_DN
Diseasepulmonary hypertension (biomarker_via_orthology)

PDE3A PDGFA PDGFB NOS2

1.54e-0580554DOID:6432 (biomarker_via_orthology)
Diseasechronic mountain sickness

AEBP2 TACC1

3.40e-055552EFO_0010143
Diseaseoligohydramnios (biomarker_via_orthology)

PDGFA PDGFB

3.40e-055552DOID:12215 (biomarker_via_orthology)
DiseaseChildhood Medulloblastoma

KAT6A EHMT1 KDM4B

7.17e-0543553C0278510
DiseaseMelanotic medulloblastoma

KAT6A EHMT1 KDM4B

7.17e-0543553C1275668
DiseaseMedullomyoblastoma

KAT6A EHMT1 KDM4B

7.17e-0543553C0205833
DiseaseDesmoplastic Medulloblastoma

KAT6A EHMT1 KDM4B

7.17e-0543553C0751291
DiseaseAdult Medulloblastoma

KAT6A EHMT1 KDM4B

7.17e-0543553C0278876
DiseaseLeydig cell tumor (is_marker_for)

PDGFA PDGFB

9.48e-058552DOID:2696 (is_marker_for)
DiseaseMedulloblastoma

KAT6A EHMT1 KDM4B

1.13e-0450553C0025149
DiseaseThrombocytosis, Autosomal Dominant

PDGFA PDGFB

1.22e-049552C3489628
DiseaseThrombocythemia, Essential

PDGFA PDGFB

2.22e-0412552C0040028
DiseaseCardiovascular Abnormalities

GATA2 NOS2

4.03e-0416552C0243050
DiseaseRetinal Diseases

PDGFB NOS2

1.16e-0327552C0035309
Diseaseleiomyoma (is_marker_for)

PDGFA PDGFB

1.25e-0328552DOID:127 (is_marker_for)
Diseaseresponse to dolutegravir

PDGFA AEBP2

1.44e-0330552EFO_0600017
DiseaseLung Neoplasms

FOXM1 BHLHE41 AVPI1 NOS2

1.51e-03265554C0024121
DiseaseMalignant neoplasm of lung

FOXM1 BHLHE41 AVPI1 NOS2

1.53e-03266554C0242379
Diseaseclear cell renal cell carcinoma (is_marker_for)

PDGFB GATA2

1.74e-0333552DOID:4467 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
KRRSLSPKPRDKSRR

PRPF4B

351

Q13523
RRSKLRKPKPVPLRK

TACC1

226

O75410
RKLKNKRRRSLPRPH

AEBP2

381

Q6ZN18
RKPREKARKPRSKSL

CAGE1

741

Q8TC20
RRKKRLRHRVPPRKP

ANKRD23

81

Q86SG2
RVLRPLKTIKRLPKL

CACNA1E

1261

Q15878
RAPVKKSRRPRLRRK

CCNO

26

P22674
KLPHRLIEKKRRDRI

BHLHE41

46

Q9C0J9
LKRLRRKRPPRQKPL

AVPI1

71

Q5T686
HLCDHKKRPKPIRRR

ADAMTS14

886

Q8WXS8
KKRPKPIRRRCNQHP

ADAMTS14

891

Q8WXS8
PLKDERRHSRKKRLI

ADAMTS20

241

P59510
VSLLQKPRHRCRKRK

CAPN14

401

A8MX76
KPRHRCRKRKPLLAI

CAPN14

406

A8MX76
KRRKVLALPSHRGPK

RBM28

666

Q9NW13
TKHLKVARRRLRPLR

RGS3

266

P49796
RRPKRREIPLKVLVK

NOS2

506

P35228
EKLIRRRKHRRSSKP

JAKMIP2

411

Q96AA8
RRKHRRSSKPIKRPV

JAKMIP2

416

Q96AA8
PRPNHKAVARRAKLK

KIAA0895

41

Q8NCT3
KKRRLHPPEDPKLRL

DPF3

81

Q92784
DLRKHRRKLLSPVSR

PPFIA4

671

O75335
LHRVPLRRHPSLKKK

CTSE

21

P14091
LRRHPSLKKKLRARS

CTSE

26

P14091
PLLPKKQKRPATRRR

DCAF12L2

36

Q5VW00
RTVRVRRPPKGKHRK

PDGFB

211

P01127
RAPPKRKRKRVKQRI

PCMTD1

271

Q96MG8
KDKLAIPKRLRRSLP

PDE3A

416

Q14432
LPKPKRRRLSKLRTR

NPIPB8

406

E9PQR5
KAKLLRRSHRKRSQP

KDM4B

366

O94953
QQLPKPKRRRLSKLR

NPIPB7

386

O75200
PELRLSKRKHRKIPF

PARP4

1231

Q9UKK3
ALRAPRKKIHRRVLK

RPL4

301

P36578
QLPKPKRRRLSKLRT

NPIPB15

396

A6NHN6
LRPKREKRPRLPRKL

INO80E

156

Q8NBZ0
TKPTLKRKKPFLHRR

KAT6A

1006

Q92794
RPLTNKLKRKRRPTS

BRCA1

496

P38398
KLKRKRRPTSGLHPE

BRCA1

501

P38398
KHLLPRKIRLSRSKP

BTBD18

256

B2RXH4
PLIKPKRRLSAARRA

GATA2

331

P23769
FLPKPRKLRNRHLRK

CRAMP1

871

Q96RY5
MKTSPRRPLILKRRR

FOXM1

1

Q08050
LTPRRKKIDRNPRVK

UTP3

421

Q9NQZ2
PWIKPARKRRRRSRK

EHMT1

436

Q9H9B1
KPKRRRLSKLRTRHC

NPIPB6

401

E9PJ23
QQLPKPKRRRLSKLR

NPIPB9

401

F8W1W9
AVRKHKPPRLSEIKR

SPHKAP

991

Q2M3C7
LLRAKPKRKIPTSRV

NUGGC

216

Q68CJ6
KRKRPRKKSPRAHRE

RRP1B

471

Q14684
KASPRRLPRKRAQKR

SSR1

266

P43307
PAKRPRLKCLLHIVR

RRP12

831

Q5JTH9
KLPRRESLRPKRKRT

TMC1

31

Q8TDI8
LRPLKKFLRKLHLPR

C17orf64

56

Q86WR6
SLIPRTPKARKRKSR

DNTTIP2

56

Q5QJE6
RPRKDPLRHLRTREK

ELAC2

31

Q9BQ52
TKHVPEKRPLPIRRK

PDGFA

71

P04085
VHRGPLPRLRLRKAK

SUSD1

596

Q6UWL2
LHKIPPRKRLRKRDS

ZNF274

441

Q96GC6
LQRGRKKDRPRKHLT

SP100

546

P23497
PKPARRRKRRKSIFV

SFMBT2

686

Q5VUG0
RVRNKLKRLIAKRPP

ARHGAP9

511

Q9BRR9
QPKHLREAVRRLKPK

nan

171

A6NLC8
PRRKKQARKARRLEP

SOX18

156

P35713
PDPPRIRYRKKKRIL

SP140

661

Q13342
RLGIHLIRRKIVKPK

XRRA1

426

Q6P2D8