Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CoA carboxylase activity	ACACA ACACB PCCA	1.77e-05	6	194	3	GO:0016421
GeneOntologyMolecularFunction	biotin binding	ACACA ACACB PCCA	1.77e-05	6	194	3	GO:0009374
GeneOntologyMolecularFunction	ligase activity, forming carbon-carbon bonds	ACACA ACACB PCCA	3.07e-05	7	194	3	GO:0016885
GeneOntologyMolecularFunction	acetyl-CoA carboxylase activity	ACACA ACACB	9.39e-05	2	194	2	GO:0003989
Domain	-	ACACA ACACB SYN3 PCCA	6.35e-06	13	186	4	3.40.50.20
Domain	PreATP-grasp_dom	ACACA ACACB SYN3 PCCA	8.82e-06	14	186	4	IPR016185
Domain	Biotin_BS	ACACA ACACB PCCA	9.58e-06	5	186	3	IPR001882
Domain	Biotin_COase_C	ACACA ACACB PCCA	9.58e-06	5	186	3	IPR005482
Domain	BC	ACACA ACACB PCCA	9.58e-06	5	186	3	PS50979
Domain	Biotin_carb_C	ACACA ACACB PCCA	9.58e-06	5	186	3	SM00878
Domain	Biotin_carb_C	ACACA ACACB PCCA	9.58e-06	5	186	3	PF02785
Domain	Biotin_carboxylation_dom	ACACA ACACB PCCA	9.58e-06	5	186	3	IPR011764
Domain	CPSASE_1	ACACA ACACB PCCA	9.58e-06	5	186	3	PS00866
Domain	BIOTIN	ACACA ACACB PCCA	9.58e-06	5	186	3	PS00188
Domain	-	ACACA ACACB SYN3 PCCA	1.19e-05	15	186	4	3.30.1490.20
Domain	Rudment_hybrid_motif	ACACA ACACB PCCA	1.90e-05	6	186	3	IPR011054
Domain	CPSASE_2	ACACA ACACB PCCA	1.90e-05	6	186	3	PS00867
Domain	ATP_grasp_subdomain_1	ACACA ACACB SYN3 PCCA	2.61e-05	18	186	4	IPR013815
Domain	-	ACACA ACACB SYN3 PCCA	2.61e-05	18	186	4	3.30.470.20
Domain	PRAME_family	PRAMEF25 PRAMEF15 PRAMEF4 PRAMEF27	3.28e-05	19	186	4	IPR026271
Domain	CbamoylP_synth_lsu-like_ATP-bd	ACACA ACACB PCCA	3.30e-05	7	186	3	IPR005479
Domain	BC-like_N	ACACA ACACB PCCA	3.30e-05	7	186	3	IPR005481
Domain	CPSase_L_D2	ACACA ACACB PCCA	3.30e-05	7	186	3	PF02786
Domain	Biotin_carb_N	ACACA ACACB PCCA	3.30e-05	7	186	3	PF00289
Domain	Biotin_lipoyl	ACACA ACACB PCCA	7.81e-05	9	186	3	PF00364
Domain	ACC_central	ACACA ACACB	9.86e-05	2	186	2	PF08326
Domain	AcCoA_COase_cen	ACACA ACACB	9.86e-05	2	186	2	IPR013537
Domain	BIOTINYL_LIPOYL	ACACA ACACB PCCA	1.11e-04	10	186	3	PS50968
Domain	Biotin_lipoyl	ACACA ACACB PCCA	1.11e-04	10	186	3	IPR000089
Domain	CRAL-bd_toc_tran	SEC14L4 SEC14L3 SEC14L6	2.00e-04	12	186	3	IPR001071
Domain	Single_hybrid_motif	ACACA ACACB PCCA	2.00e-04	12	186	3	IPR011053
Domain	CRAL_TRIO_N	SEC14L4 SEC14L3 SEC14L6	2.00e-04	12	186	3	SM01100
Domain	ATP_grasp_subdomain_2	ACACA ACACB SYN3 PCCA	2.43e-04	31	186	4	IPR013816
Domain	ATP_GRASP	ACACA ACACB PCCA	3.26e-04	14	186	3	PS50975
Domain	ATP-grasp	ACACA ACACB PCCA	3.26e-04	14	186	3	IPR011761
Domain	CRAL/TRIO_N_dom	SEC14L4 SEC14L3 SEC14L6	4.05e-04	15	186	3	IPR011074
Domain	Pecanex_C	PCNX3 PCNX1	5.84e-04	4	186	2	PF05041
Domain	Carboxyl_trans	ACACA ACACB	5.84e-04	4	186	2	PF01039
Domain	COA_CT_CTER	ACACA ACACB	5.84e-04	4	186	2	PS50989
Domain	COA_CT_NTER	ACACA ACACB	5.84e-04	4	186	2	PS50980
Domain	COA_CT_N	ACACA ACACB	5.84e-04	4	186	2	IPR011762
Domain	COA_CT_C	ACACA ACACB	5.84e-04	4	186	2	IPR011763
Domain	Pecanex	PCNX3 PCNX1	5.84e-04	4	186	2	IPR007735
Domain	Carboxyl_trans	ACACA ACACB	5.84e-04	4	186	2	IPR000022
Domain	GOLD_dom	SEC14L4 SEC14L3 SEC14L6	8.37e-04	19	186	3	IPR009038
Domain	GOLD	SEC14L4 SEC14L3 SEC14L6	8.37e-04	19	186	3	PS50866
Domain	CRAL_TRIO	SEC14L4 SEC14L3 SEC14L6	1.13e-03	21	186	3	PF00650
Domain	SURP	CHERP U2SURP	1.44e-03	6	186	2	PS50128
Domain	Surp	CHERP U2SURP	1.44e-03	6	186	2	PF01805
Domain	SWAP	CHERP U2SURP	1.44e-03	6	186	2	SM00648
Domain	Surp	CHERP U2SURP	1.44e-03	6	186	2	IPR000061
Domain	-	SEC14L4 SEC14L3 SEC14L6	1.49e-03	23	186	3	3.40.525.10
Domain	SEC14	SEC14L4 SEC14L3 SEC14L6	1.90e-03	25	186	3	SM00516
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SF3B4 ACACA DDX1 GAB2 FSIP2 DLC1 MDN1 FAM83G HELZ BICC1 RAP1GAP TCF20 PARP8 SIK3 STIL FRMD6 EIF4G1 GAN SRPK3 LIMCH1 USP54 PARD3 RNF180	7.97e-10	861	196	23	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACACA DHX38 STAU1 MDN1 XPO5 ATAD2B HELZ HERC2 PRRC2B FLNC CHERP POLR1A TCF20 U2SURP DIDO1 UPF1 CSE1L EIF4G1 MRTO4 PRKDC	1.08e-09	653	196	20	22586326
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SF3B4 ACACA ACACB DHX38 ADAR HNRNPH2 DDX1 EIF3CL MDN1 XPO5 HELZ DDX39B CHERP POLR1A U2SURP SMPD4 DIDO1 UPF1 TERT RSBN1 EIF4G1 MRTO4 PRKDC LRBA SNRPA PCCA	3.13e-08	1318	196	26	30463901
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	TRIM25 ACACA DDX1 STAU1 MDN1 UFD1 SCN8A UNC79 FLNC UPF1 MYOF CSE1L EIF4G1 DAAM2 PCNX1 PRKDC LRBA PCCA DISP1 DNPEP	3.73e-08	807	196	20	30575818
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FAM120B SF3B4 WDR33 ADAR HNRNPH2 DDX1 STAU1 SYNGAP1 SUN2 DHX35 DDX39B FLNC CHERP TCF20 U2SURP SMPD4 DIDO1 UPF1 SIK3 CSE1L EIF4G1 PRKDC SNRPA	5.54e-08	1082	196	23	38697112
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	FRMPD4 MDN1 PTPRN2 HERC2 U2SURP DIDO1 DAAM2 PCDHGA8	1.43e-07	104	196	8	9205841
Pubmed	Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice.	NR1I2 NR1I3 UGT1A1	1.76e-07	3	196	3	22371261
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SF3B4 WDR33 DHX38 ADAR HNRNPH2 DDX1 STAU1 XPO5 HELZ DDX39B PRRC2B RPF1 CHERP U2SURP DIDO1 UPF1 MRTO4 PRKDC SNRPA	1.83e-07	807	196	19	22681889
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FAM120B TRIM25 ACACA UBE4B DHX38 TSC1 ADAR HNRNPH2 DDX1 STAU1 MDN1 UFD1 HERC2 DDX39B FLNC POLR1A TCF20 U2SURP UPF1 CSE1L EIF4G1 MRTO4 PRKDC PARD3 SNRPA	2.03e-07	1353	196	25	29467282
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	ACACA DHX38 ADAR DDX1 STAU1 CLPB XPO5 UFD1 RPF1 U2SURP UPF1 RSBN1 CSE1L MRTO4 PRKDC SNRPA DNPEP	2.08e-07	653	196	17	33742100
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	TRIM25 ACACA DHX38 ADAR HNRNPH2 STAU1 CLPB DHX35 HERC2 DDX39B POLR1A UPF1 ACTR6 USP54	2.39e-07	440	196	14	34244565
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	HDAC9 SF3B4 UBE4B GATM ZNF227 SYNGAP1 CADM1 CLPB PTPRK RNF216 DHX35 TAF1 HERC2 MTUS2 CNTN4 RAP1GAP OXR1 EIF4G1 LRP1 DAAM2 PRKDC USP54 LRBA USPL1	3.00e-07	1285	196	24	35914814
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SF3B4 UBE4B WDR33 ZNF227 SYNGAP1 CADM1 PTPRK XPO5 SUN2 RNF216 TMX3 GNPAT FLNC CHERP TCF20 SMPD4 RSBN1 ATP6V1H CSE1L EIF4G1 LRP1 PRKDC RERE	3.60e-07	1203	196	23	29180619
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	PCNX3 PKD1L1 MECOM SEMA3G DNAH14 HEPH TBC1D9 SYNGAP1 SUN2 HACE1 FAM83G BCAR3 HERC2 PRRC2B CNTN4 CHERP DIDO1 SEC14L6 AP5B1 SERPINE1 USP54 SNRPA DNPEP	4.28e-07	1215	196	23	15146197
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	TRIM25 HNRNPH2 DDX1 MDN1 XPO5 TAF1 DDX39B DIDO1 UPF1 CSE1L EIF4G1 PRKDC	4.66e-07	332	196	12	32786267
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	ADAR HNRNPH2 DDX1 XPO5 TCF20 U2SURP DIDO1 CSE1L PRKDC RERE	5.48e-07	220	196	10	35785414
Pubmed	Human transcription factor protein interaction networks.	ACACB WDR33 MECOM DDX1 STAU1 KLF5 NFKB1 HELZ TAF1 HERC2 PRRC2B TCF20 DIDO1 UPF1 RSBN1 CSE1L ZFHX4 ACTR6 EIF4G1 LRP6 MRTO4 ELK3 RERE USP54 PCCA	5.56e-07	1429	196	25	35140242
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	SF3B4 ACACA ADAR DDX1 STAU1 MDN1 XPO5 DDX39B CHERP UPF1 CSE1L YKT6 EIF4G1 PRKDC LRBA SNRPA	7.84e-07	638	196	16	33239621
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	TRIM25 ACACA ACACB SYNGAP1 HELZ U2SURP PCCA	8.16e-07	90	196	7	35654790
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	TRIM25 ACACA ACACB DHX38 ADAR STAU1 DDX39B PRRC2B DIDO1 CSE1L PRKDC PCCA	1.00e-06	357	196	12	37059091
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACA ACACB TSC1 PARVG SYNGAP1 PTPRB MDN1 RIC1 POLR1A U2SURP GAN LIMCH1 LRBA DNPEP	1.02e-06	497	196	14	36774506
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SF3B4 ACACA NR1I2 FBXL7 CLPB XPO5 FIG4 CHERP SMPD4 DIDO1 APOB UPF1 MYOF EIF4G1 MRTO4 LIMCH1 SNRPA	1.50e-06	754	196	17	35906200
Pubmed	Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR.	NR1I2 NR1I3 UGT1A1	1.75e-06	5	196	3	36720308
Pubmed	Reduced expression of UGT1A1 in intestines of humanized UGT1 mice via inactivation of NF-κB leads to hyperbilirubinemia.	NR1I2 NR1I3 UGT1A1	1.75e-06	5	196	3	21983082
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TRIM25 ACACA DHX38 ADAR DDX1 EIF3CL STAU1 MDN1 CLPB XPO5 MYO18B DDX39B CHERP POLR1A U2SURP APOB UPF1 ATP6V1H CSE1L EIF4G1 MRTO4 PRKDC SNRPA DNPEP	1.85e-06	1425	196	24	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FAM120B TRIM25 SYN3 TSC1 DDX1 EIF3CL STAU1 EHD3 SYNGAP1 DDX39B MTUS2 WNK2 PRRC2B FLNC RAP1GAP OXR1 UPF1 OR52E2 ATP6V1H CSE1L EIF4G1 LIMCH1 USP54 DNPEP	1.99e-06	1431	196	24	37142655
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	WDR33 DDX1 MDN1 TAF1 POLR1A TCF20 U2SURP DIDO1 CSE1L ACTR6 PRKDC SNRPA	2.78e-06	394	196	12	27248496
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	FAM120B ADAR HNRNPH2 DDX1 STAU1 DDX39B PRRC2B FLNC CHERP U2SURP UPF1 EIF4G1 PRKDC SNRPA	3.37e-06	551	196	14	34728620
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	ACACA DHX38 ADAR HNRNPH2 DDX1 STAU1 MDN1 XPO5 UFD1 DDX39B RPF1 FLNC CHERP TCF20 U2SURP DIDO1 MRTO4 PRKDC PCCA	3.72e-06	989	196	19	36424410
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ACACA PCNX3 UBE4B NPHP4 TBC1D9 MDN1 SCN8A HERC2 WNK2 ABCC10 RIC1 PRRC2B ENGASE FLNC MYOF EIF4G1 PCNX1 SENP2 PRKDC LRBA	4.96e-06	1105	196	20	35748872
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	ACACA STAU1 XPO5 SUN2 HELZ PRRC2B CHERP U2SURP UPF1 SIK3 RSBN1 CSE1L PRKDC RERE USP54	5.27e-06	655	196	15	35819319
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ACACB DHX38 NPHP4 PTPRB HERC2 RPF1 MUC16 APOB STIL CSE1L LRP1 PCNX1	5.32e-06	420	196	12	28065597
Pubmed	Modulating HIV-1 RNA processing and utilization.	DDX1 STAU1 EIF4G1	6.07e-06	7	196	3	18508616
Pubmed	CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women.	CETP APOB SERPINE1	6.07e-06	7	196	3	18665040
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SF3B4 WDR33 ADAR DDX1 STAU1 ATAD2B TAF1 DDX39B CHERP TCF20 U2SURP DIDO1 ZDBF2 RSBN1 EIF4G1 PRKDC SNRPA PCCA	8.66e-06	954	196	18	36373674
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDE4C ACACA UBE4B TBC1D9 EIF3CL MDN1 HELZ TCF20 DIDO1 MYOF EIF4G1 ELK3 LIMCH1 PRKDC RERE PARD3	9.16e-06	774	196	16	15302935
Pubmed	Methylenetetrahydrofolate reductase C677T polymorphism is associated with central adiposity and increased androgenicity in healthy postmenopausal women.	CETP APOB SERPINE1	9.67e-06	8	196	3	18728123
Pubmed	The frequency of early, spontaneous miscarriage associated with the leu33pro polymorphism of Glycoprotein IIIa: a pilot study.	CETP APOB SERPINE1	9.67e-06	8	196	3	21039385
Pubmed	Nectins localize Willin to cell-cell junctions.	CADM1 FRMD6 PARD3	9.67e-06	8	196	3	22512338
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	DHX38 MECOM ADAR DDX1 STAU1 MDN1 DDX39B CHERP U2SURP CSE1L ZFHX4 EIF4G1 MRTO4 PRKDC	9.73e-06	605	196	14	28977666
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TSC1 EHD3 SYNGAP1 MDN1 PTPRN2 HERC2 UNC79 WNK2 PRRC2B CNTN4 TCF20 DIDO1 UPF1 SIK3 EIF4G1 LRP1 LIMCH1 PARD3	9.82e-06	963	196	18	28671696
Pubmed	Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.	SF3B4 ADAR HNRNPH2 DDX1 STAU1 DDX39B UPF1 CSE1L PRKDC	1.01e-05	241	196	9	23125841
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	FAM120B SF3B4 ACACA ACACB ADAR HNRNPH2 MDN1 DDX39B DIDO1 STIL ATP6V1H CSE1L SNRPA PCCA	1.37e-05	624	196	14	33729478
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	TRIM25 CLPB DDX39B PRRC2B RPF1 TCF20 U2SURP UPF1 EIF4G1 MRTO4 SNRPA	2.01e-05	403	196	11	35253629
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	UFD1 HELZ PRRC2B TCF20 SMPD4 SENP2 USP54 LRBA PARD3	2.01e-05	263	196	9	34702444
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	CETP SORT1 APOB LRP1	2.08e-05	29	196	4	20167577
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	DDX1 DLC1 FIG4 TMX3 PCNX1 UNC13C MAML2 PARD3 IGSF21	2.14e-05	265	196	9	19240061
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMPD4 UBE4B TSC1 XPO5 PRRC2B TCF20 RSBN1 DAAM2 SENP2 LIMCH1 RERE	2.20e-05	407	196	11	12693553
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TRIM25 ADAR HNRNPH2 DDX1 STAU1 MDN1 HERC2 DDX39B FLNC CHERP POLR1A TCF20 U2SURP CSE1L EIF4G1 MRTO4 PRKDC SNRPA	2.22e-05	1024	196	18	24711643
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TRIM25 DDX1 STAU1 SORT1 MDN1 CLPB XPO5 SUN2 NFKB1 UFD1 TMX3 PRRC2B SMPD4 UPF1 MYOF ATP6V1H CSE1L EIF4G1 SERPINE1 MRTO4 LIMCH1 PRKDC	2.32e-05	1440	196	22	30833792
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	DDX1 STAU1 DDX39B MYOF CSE1L EIF4G1 MRTO4 LIMCH1 PRKDC	2.34e-05	268	196	9	33024031
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TRIM25 ACACA ACACB DHX38 TSC1 ADAR STAU1 HELZ PRRC2B CHERP U2SURP DIDO1 UPF1 YKT6 PRKDC LRBA PCCA	2.45e-05	934	196	17	33916271
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	SF3B4 TRIM25 ADAR HNRNPH2 DDX1 DDX39B POLR1A U2SURP UPF1 MYOF EIF4G1 MRTO4 PRKDC SNRPA	2.55e-05	660	196	14	32780723
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	SF3B4 TRIM25 ADAR DDX1 DDX39B CHERP TCF20 UPF1 EIF4G1	2.78e-05	274	196	9	34244482
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ACACA ACACB MECOM TAF1 TCF20 ZDBF2 ZFHX4 LRP1 RERE LRBA PCCA	2.81e-05	418	196	11	34709266
Pubmed	Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.	DDX1 APOB LRP6	2.81e-05	11	196	3	28978771
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	TAF1 DDX39B CHERP U2SURP UPF1 PRKDC	2.85e-05	104	196	6	31365120
Pubmed	Analysis of common polymorphisms within NR1I2 and NR1I3 genes and tacrolimus dose-adjusted concentration in stable kidney transplant recipients.	NR1I2 NR1I3	3.16e-05	2	196	2	28777242
Pubmed	Association of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity.	NR1I2 NR1I3	3.16e-05	2	196	2	30778091
Pubmed	Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation.	ACACA ACACB	3.16e-05	2	196	2	24944901
Pubmed	Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.	SORT1 APOB	3.16e-05	2	196	2	22751103
Pubmed	Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.	NR1I2 NR1I3	3.16e-05	2	196	2	15684063
Pubmed	Polymorphisms in regulators of xenobiotic transport and metabolism genes PXR and CAR do not affect multiple myeloma risk: a case-control study in the context of the IMMEnSE consortium.	NR1I2 NR1I3	3.16e-05	2	196	2	23303387
Pubmed	Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.	NR1I2 NR1I3	3.16e-05	2	196	2	11114890
Pubmed	Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.	ACACA ACACB	3.16e-05	2	196	2	20139635
Pubmed	The roles of nuclear receptors CAR and PXR in hepatic energy metabolism.	NR1I2 NR1I3	3.16e-05	2	196	2	18305370
Pubmed	Genetic variations of the xenoreceptors NR1I2 and NR1I3 and their effect on drug disposition and response variability.	NR1I2 NR1I3	3.16e-05	2	196	2	29199543
Pubmed	Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.	ACACA ACACB	3.16e-05	2	196	2	26976583
Pubmed	Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.	NR1I2 NR1I3	3.16e-05	2	196	2	24690595
Pubmed	Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis.	NR1I2 NR1I3	3.16e-05	2	196	2	16973756
Pubmed	Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.	NR1I2 UGT1A1	3.16e-05	2	196	2	22829544
Pubmed	Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair.	PRKDC PARD3	3.16e-05	2	196	2	17287830
Pubmed	The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.	NR1I2 NR1I3	3.16e-05	2	196	2	15358766
Pubmed	Regulation of CAR and PXR Expression in Health and Disease.	NR1I2 NR1I3	3.16e-05	2	196	2	33142929
Pubmed	Non-structural protein 1 of influenza viruses inhibits rapid mRNA degradation mediated by double-stranded RNA-binding protein, staufen1.	STAU1 UPF1	3.16e-05	2	196	2	23722113
Pubmed	Genetic polymorphisms in PXR and NF-κB1 influence susceptibility to anti-tuberculosis drug-induced liver injury.	NR1I2 NFKB1	3.16e-05	2	196	2	31490979
Pubmed	Expression of deleted in liver cancer 1 and plasminogen activator inhibitor 1 protein in ovarian carcinoma and their clinical significance.	DLC1 SERPINE1	3.16e-05	2	196	2	23988121
Pubmed	IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation.	TRIM25 ADAR	3.16e-05	2	196	2	35935998
Pubmed	Plasma plasminogen activator inhibitor-1 level is not regulated by the hepatic low-density lipoprotein receptor-related protein.	SERPINE1 LRP1	3.16e-05	2	196	2	17958748
Pubmed	The subcellular localization of acetyl-CoA carboxylase 2.	ACACA ACACB	3.16e-05	2	196	2	10677481
Pubmed	Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice.	NR1I2 NR1I3	3.16e-05	2	196	2	30573465
Pubmed	Ligand dependent hepatic gene expression profiles of nuclear receptors CAR and PXR.	NR1I2 NR1I3	3.16e-05	2	196	2	22698814
Pubmed	Polymorphisms at CYP enzymes, NR1I2 and NR1I3 in association with virologic response to antiretroviral therapy in Brazilian HIV-positive individuals.	NR1I2 NR1I3	3.16e-05	2	196	2	34504302
Pubmed	Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk.	LRP1 LRP6	3.16e-05	2	196	2	26031789
Pubmed	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.	ACACA ACACB	3.16e-05	2	196	2	25282359
Pubmed	Acetyl-CoA carboxylase rewires cancer metabolism to allow cancer cells to survive inhibition of the Warburg effect by cetuximab.	ACACA ACACB	3.16e-05	2	196	2	27693630
Pubmed	Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.	ACACA ACACB	3.16e-05	2	196	2	32215608
Pubmed	Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease.	NR1I2 NFKB1	3.16e-05	2	196	2	31581194
Pubmed	Activity and structure of human acetyl-CoA carboxylase targeted by a specific inhibitor.	ACACA ACACB	3.16e-05	2	196	2	29772612
Pubmed	Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line.	NR1I2 NR1I3	3.16e-05	2	196	2	21628639
Pubmed	A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.	NR1I2 NR1I3	3.16e-05	2	196	2	14742670
Pubmed	Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation.	NR1I2 NR1I3	3.16e-05	2	196	2	35212371
Pubmed	Expression of hepatic cytochrome P450s and UDP-glucuronosyltransferases in PXR and CAR double humanized mice treated with rifampicin.	NR1I2 NR1I3	3.16e-05	2	196	2	25835148
Pubmed	The ternary complex factor Net regulates cell migration through inhibition of PAI-1 expression.	SERPINE1 ELK3	3.16e-05	2	196	2	16314510
Pubmed	Blocking AMPK signalling to acetyl-CoA carboxylase increases cisplatin-induced acute kidney injury and suppresses the benefit of metformin.	ACACA ACACB	3.16e-05	2	196	2	36076520
Pubmed	Use of rhenium-188 for in vivo imaging and treatment of human cervical cancer cells transfected with lentivirus expressing sodium iodide symporter.	TERT SLC5A5	3.16e-05	2	196	2	27573304
Pubmed	Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR.	NR1I2 NR1I3	3.16e-05	2	196	2	24863967
Pubmed	Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.	ACACA ACACB	3.16e-05	2	196	2	30244972
Pubmed	Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression.	NR1I2 NR1I3	3.16e-05	2	196	2	28756207
Pubmed	CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation.	CADM1 NFKB1	3.16e-05	2	196	2	29698475
Interaction	SIRT7 interactions	TRIM25 ACACA DHX38 STAU1 MDN1 XPO5 ATAD2B HELZ HERC2 PRRC2B FLNC CHERP POLR1A TCF20 U2SURP DIDO1 UPF1 CSE1L EIF4G1 MRTO4 PRKDC	4.67e-06	744	184	21	int:SIRT7
Interaction	SUMO2 interactions	HDAC9 TRIM25 HNRNPH2 DDX1 MDN1 UBE2H XPO5 RNF216 TAF1 DDX39B DIDO1 UPF1 CSE1L EIF4G1 SENP2 ELK3 PRKDC USPL1	8.40e-06	591	184	18	int:SUMO2
Interaction	BTRC interactions	TRIM25 ACACA ACACB UBE4B DHX38 ADAR DDX1 TBC1D10C MDN1 SUN2 NFKB1 UFD1 RNF128 DDX39B PRRC2B RAP1GAP UPF1 STIL EIF4G1 USP54 FAM219A	8.71e-06	775	184	21	int:BTRC
Interaction	PRMT1 interactions	FAM120B TRIM25 UBE4B WDR33 MECOM ADAR HNRNPH2 DDX1 STAU1 NR1I2 UBE2H DDX39B PRRC2B FLNC CHERP U2SURP UPF1 EIF4G1 GAN PRKDC SAMD3 SNRPA IGSF21	1.37e-05	929	184	23	int:PRMT1
Interaction	STIP1 interactions	SF3B4 TRIM25 ACACA NPHP4 ADAR DDX1 STAU1 SYNGAP1 FBXL7 MDN1 UBE2H XPO5 UFD1 DDX39B CHERP UPF1 SIK3 STIL CSE1L YKT6 EIF4G1 PRKDC LRBA SNRPA	1.61e-05	1006	184	24	int:STIP1
Interaction	MTTP interactions	PTPRN2 APOB LRP1 PRKDC	2.34e-05	19	184	4	int:MTTP
Interaction	MIR363 interactions	SF3B4 TRIM25 HNRNPH2 DDX1 CHERP U2SURP UPF1	3.03e-05	97	184	7	int:MIR363
Interaction	FMR1 interactions	TSC1 ADAR DDX1 STAU1 EHD3 SYNGAP1 UBE2H PTPRN2 HERC2 PRRC2B TCF20 UPF1 SIK3 EIF4G1 LRP1 PARD3	3.46e-05	536	184	16	int:FMR1
Interaction	FBXO22 interactions	TRIM25 ACACA ACACB TSC1 PARVG SYNGAP1 PTPRB MDN1 UBE2H RIC1 POLR1A U2SURP GAN LIMCH1 LRBA DNPEP	3.79e-05	540	184	16	int:FBXO22
Interaction	AR interactions	TRIM25 WDR33 ADAR HNRNPH2 DDX1 MDN1 XPO5 KLF5 NFKB1 TAF1 PRRC2B CHERP TCF20 U2SURP DIDO1 CSE1L AP5B1 SENP2 LIMCH1 PRKDC RERE USP54 SMAD1	3.82e-05	992	184	23	int:AR
Interaction	MS4A4A interactions	XPO5 TMX3 ATP6V1H CSE1L PRKDC	3.89e-05	42	184	5	int:MS4A4A
Interaction	USP53 interactions	TRIM25 ACACA ACACB SYNGAP1 HELZ FLNC U2SURP PCCA	4.01e-05	138	184	8	int:USP53
Interaction	ISG15 interactions	SF3B4 TRIM25 WDR33 DDX1 STAU1 UFD1 DDX39B SIK3 MYOF CSE1L EIF4G1 MRTO4 LIMCH1 PRKDC KLHL26	5.06e-05	494	184	15	int:ISG15
Interaction	ARHGAP32 interactions	TRIM25 TSC1 GAB2 SYNGAP1 SORT1 PTPRK STIL PARD3	6.90e-05	149	184	8	int:ARHGAP32
Interaction	NR2C2 interactions	SF3B4 TRIM25 ACACA ACACB DHX38 ADAR HNRNPH2 DDX1 EIF3CL MDN1 XPO5 HELZ DDX39B CHERP POLR1A U2SURP SMPD4 DIDO1 UPF1 TERT RSBN1 EIF4G1 MRTO4 ELK3 PRKDC LRBA SNRPA PCCA	7.53e-05	1403	184	28	int:NR2C2
Interaction	MIR92A1 interactions	SF3B4 TRIM25 HNRNPH2 DDX1 U2SURP UPF1	7.95e-05	78	184	6	int:MIR92A1
Interaction	EIF3D interactions	TRIM25 MECOM EIF3CL STAU1 UBE2H HERC2 MTUS2 PRRC2B EIF4G1 GAN	8.55e-05	244	184	10	int:EIF3D
Interaction	YWHAQ interactions	TRIM25 ACACA TSC1 DDX1 GAB2 STAU1 UBE2H CLPB NFKB1 FAM83G UNC79 BICC1 RAP1GAP PARP8 UPF1 SIK3 TERT CSE1L FRMD6 EIF4G1 PRKDC USP54 LRBA PARD3	8.60e-05	1118	184	24	int:YWHAQ
Interaction	CPEB4 interactions	TRIM25 DDX1 STAU1 HELZ TAF1 PRRC2B UPF1 USP54	9.52e-05	156	184	8	int:CPEB4
Cytoband	1p36.21	PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4	1.58e-04	63	196	4	1p36.21
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	PRAMEF25 PRAMEF9 UBE4B NPHP4 RAP1GAP PRAMEF15 PRAMEF4 MRTO4 RERE IGSF21 PRAMEF27	1.84e-04	681	196	11	chr1p36
Cytoband	5q11.1	EMB PARP8	4.99e-04	8	196	2	5q11.1
GeneFamily	PRAME family	PRAMEF25 PRAMEF9 PRAMEF15 PRAMEF4 PRAMEF27	7.88e-07	24	134	5	686
GeneFamily	SEC14 family\|PRELI domain containing	SEC14L4 SEC14L3 SEC14L6	7.83e-06	6	134	3	1063
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRB PTPRK PTPRN2	4.80e-04	21	134	3	813
GeneFamily	Immunoglobulin like domain containing	SEMA3G CADM1 PTPRK SEMA3B CNTN4 EMB IGSF21	5.94e-04	193	134	7	594
GeneFamily	Exportins	XPO5 CSE1L	1.12e-03	7	134	2	547
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	MECOM DNAH14 CADM1 BICC1 OXR1 FHOD3 SIK3 LIMCH1 MAML2 RERE LRBA PCCA	4.53e-08	208	191	12	M39233
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	DNAH14 PTPRK BICC1 CNTN4 MACC1 OXR1 FHOD3 MAML2 RERE PARD3	7.10e-07	176	191	10	M39223
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	MECOM FBXL7 DLC1 MDN1 PTPRK NFKB1 ATAD2B HELZ BCAR3 CHST3 U2SURP SIK3 STIL RSBN1 MYOF ATP6V1H CSE1L SERPINE1 PARD3 PCCA	4.89e-06	856	191	20	M4500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500	GATM GDPD2 SYNGAP1 NRK RNF128 PCDH18 CNTN4 FLNC MUC16 ZFHX4 ACTR6 LRP1 DAAM2	1.12e-05	357	179	13	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500	GDPD2 SYNGAP1 NRK RNF128 PCDH18 CNTN4 FLNC MUC16 MYOF ZFHX4 ACTR6 LRP1 DAAM2	2.68e-05	388	179	13	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	NRK RNF128 PCDH18 CNTN4 FLNC EMB MUC16 ZDBF2 MYOF ZFHX4 ACTR6 LRP1 DAAM2	5.76e-05	418	179	13	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500	GATM GDPD2 SYNGAP1 NRK RNF128 PCDH18 CNTN4 FLNC MUC16 ACTR6 LRP1 DAAM2	7.89e-05	372	179	12	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500	DLC1 NRK BICC1 FLNC MUC16 ZDBF2 MYOF LRP1	8.12e-05	165	179	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_200	NRK PCDH18 FLNC MUC16	8.54e-05	28	179	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k1_200
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK CNTN4 LRP6 LIMCH1 USP54 PARD3	4.87e-11	191	193	12	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK KLF5 CNTN4 LIMCH1 USP54 PARD3	5.18e-11	192	193	12	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK CNTN4 LRP6 LIMCH1 USP54 PARD3	5.18e-11	192	193	12	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM GAB2 CADM1 PTPRK SIK3 LIMCH1 MAML2 RERE LRBA PARD3 PCCA	7.41e-11	198	193	12	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 CADM1 PTPRK KLF5 CNTN4 MACC1 LIMCH1 USP54 LRBA	6.40e-10	187	193	11	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK CNTN4 MACC1 LIMCH1 USP54 PARD3	8.01e-10	191	193	11	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACACA MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK LIMCH1 USP54 LRBA PARD3	9.98e-10	195	193	11	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM CADM1 PTPRK SIK3 LIMCH1 MAML2 RERE LRBA PARD3 PCCA	1.05e-09	196	193	11	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Control\|World / group, cell type (main and fine annotations)	MECOM C8orf34 CADM1 DLC1 PTPRK PTPRN2 CNTN4 LIMCH1 USP54 PARD3	3.49e-09	168	193	10	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2A7 ACACA MECOM C8orf34 CADM1 PTPRK CNTN4 LIMCH1 USP54 PARD3	6.09e-09	178	193	10	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	CYP2A7 MECOM C8orf34 PTPRK CNTN4 MACC1 LGSN LIMCH1 USP54 PARD3	7.14e-09	181	193	10	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 CADM1 PTPRK CNTN4 LRP6 LIMCH1 USP54 PARD3	8.81e-09	185	193	10	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MECOM C8orf34 DNAH14 CADM1 PTPRK KLF5 CNTN4 MACC1 USP54 LRBA	9.27e-09	186	193	10	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	PDE4C C8orf34 CADM1 DLC1 PTPRK KLF5 RAP1GAP LIMCH1 USP54 PARD3	1.03e-08	188	193	10	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRK BICC1 OXR1 FHOD3 SIK3 MAML2 RERE LRBA PARD3 PCCA	1.26e-08	192	193	10	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MECOM DNAH14 CADM1 PTPRK KLF5 SEMA3B MACC1 LIMCH1 USP54 PARD3	1.32e-08	193	193	10	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DNAH14 BICC1 MACC1 OXR1 FHOD3 RERE LRBA PARD3 PCCA	1.46e-08	195	193	10	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM SORT1 CADM1 UBE2H BICC1 MACC1 FHOD3 ZFHX4 UNC13C LRBA	1.53e-08	196	193	10	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM C8orf34 DNAH14 CADM1 PTPRK LRP6 LIMCH1 USP54 PARD3	1.77e-08	199	193	10	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK LIMCH1 USP54 PARD3	1.77e-08	199	193	10	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 CADM1 PTPRK CNTN4 LIMCH1 USP54 PARD3	5.93e-08	170	193	9	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MECOM C8orf34 CADM1 PTPRK KLF5 CNTN4 MACC1 USP54 LRBA	9.23e-08	179	193	9	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 CADM1 NRK BICC1 UNC13C LIMCH1 MAML2 LRBA	1.06e-07	182	193	9	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	HDAC9 CYP2J2 SORT1 CADM1 RNF216 MYO18B MTUS2 FLNC FHOD3	1.06e-07	182	193	9	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	PDE4C CADM1 DLC1 PTPRK KLF5 RAP1GAP LIMCH1 USP54 PARD3	1.11e-07	183	193	9	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	ACACA MECOM C8orf34 PTPRK WNK2 CNTN4 LIMCH1 USP54 PARD3	1.22e-07	185	193	9	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	MECOM TBC1D9 CADM1 UBE2H NRK BICC1 FHOD3 LIMCH1 PCCA	1.40e-07	188	193	9	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK LIMCH1 USP54 PARD3	1.40e-07	188	193	9	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB MECOM CADM1 BICC1 OXR1 SIK3 MAML2 RERE LRBA	1.47e-07	189	193	9	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACACB CYP2J2 HEPH FBXL7 CDH20 SEMA3B ZFHX4 DAAM2 MAML2	1.53e-07	190	193	9	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACACB CYP2J2 HEPH FBXL7 CDH20 SEMA3B ZFHX4 DAAM2 MAML2	1.60e-07	191	193	9	f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 DNAH14 DLC1 PTPRK CNTN4 RAP1GAP LIMCH1	1.68e-07	192	193	9	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	DNAH14 STAU1 CADM1 PTPRK SCN8A WNK2 DIDO1 LRP6 PARD3	1.75e-07	193	193	9	503a979328c68b096680b71359a26f02fafdff35
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 SORT1 KLF5 FBXO34 MACC1 UNC13C LRBA ANKFN1	1.83e-07	194	193	9	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACACA MECOM DNAH14 CADM1 DLC1 PTPRK LIMCH1 USP54 PARD3	1.83e-07	194	193	9	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH14 PTPRK BICC1 CNTN4 MACC1 OXR1 FHOD3 PARD3 PCCA	1.83e-07	194	193	9	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DNAH14 CADM1 BICC1 RAP1GAP OXR1 FHOD3 RERE LRBA	2.00e-07	196	193	9	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM C8orf34 DNAH14 CADM1 DLC1 PTPRK LIMCH1 PARD3	2.27e-07	199	193	9	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM C8orf34 DNAH14 CADM1 PTPRK LIMCH1 USP54 PARD3	2.27e-07	199	193	9	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA MECOM SIK3 LIMCH1 MAML2 RERE LRBA PARD3 PCCA	2.27e-07	199	193	9	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NFKB1 BICC1 CNTN4 MYOF FRMD6 SERPINE1 LRP1 LRP6 LIMCH1	2.27e-07	199	193	9	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Macroglial\|World / cells hierarchy compared to all cells using T-Statistic	ACACB CYP2J2 HEPH FBXL7 CDH20 SEMA3B ZFHX4 DAAM2 MAML2	2.37e-07	200	193	9	e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MECOM C8orf34 CADM1 PTPRK CNTN4 LIMCH1 USP54 PARD3	1.18e-06	179	193	8	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 CADM1 DLC1 PTPRK LIMCH1 PARD3	1.40e-06	183	193	8	6847c1252d6bb105524f812658112517fd351eab
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 C8orf34 BICC1 CNTN4 MACC1 OXR1 MAML2 PARD3	1.40e-06	183	193	8	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM CADM1 SEMA3B BCAR3 SLC27A5 CHST3 DAAM2 IGSF21	1.40e-06	183	193	8	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 PTPRK CNTN4 UNC13C LIMCH1 USP54	1.45e-06	184	193	8	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 PTPRK KLF5 UNC13C LIMCH1 USP54	1.51e-06	185	193	8	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MECOM CADM1 DLC1 PTPRK KLF5 LIMCH1 USP54 PARD3	1.58e-06	186	193	8	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACACB CYP2J2 FBXL7 CDH20 SEMA3B ZFHX4 DAAM2 MAML2	1.71e-06	188	193	8	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM GDPD2 CADM1 CDH20 SEMA3B UNC79 RAP1GAP IGSF21	1.71e-06	188	193	8	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM GDPD2 CADM1 CDH20 SEMA3B UNC79 RAP1GAP IGSF21	1.71e-06	188	193	8	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MECOM C8orf34 CADM1 PTPRK KLF5 LIMCH1 USP54 PARD3	1.71e-06	188	193	8	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 CADM1 FHOD3 UNC13C LIMCH1 MAML2 LRBA	1.71e-06	188	193	8	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C8orf34 DNAH14 BICC1 CNTN4 MACC1 OXR1 MAML2 PARD3	1.71e-06	188	193	8	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACACB CYP2J2 FBXL7 CDH20 SEMA3B ZFHX4 DAAM2 MAML2	1.78e-06	189	193	8	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ACACA ACACB SYN3 CADM1 SERPINE1 UNC13C RERE LRBA	1.85e-06	190	193	8	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ACACB CYP2J2 FBXL7 CDH20 SEMA3B ZFHX4 DAAM2 MAML2	1.85e-06	190	193	8	07f21386ea6eb23416a537d2250e3042efe93fb0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 CADM1 FHOD3 UNC13C LIMCH1 MAML2 LRBA	1.85e-06	190	193	8	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM C8orf34 CADM1 DLC1 PTPRK LIMCH1 PARD3	1.92e-06	191	193	8	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 SORT1 CADM1 FBXO34 MACC1 UNC13C LRBA	1.92e-06	191	193	8	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MECOM DNAH14 CADM1 DLC1 PTPRK MACC1 LIMCH1 USP54	1.92e-06	191	193	8	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	AOC1 ACACB SYN3 SORT1 FBXL7 DAAM2 UNC13C LRBA	2.00e-06	192	193	8	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACACA MECOM C8orf34 CADM1 DLC1 PTPRK LIMCH1 PARD3	2.08e-06	193	193	8	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ACACA MECOM C8orf34 CADM1 DLC1 PTPRK LIMCH1 PARD3	2.08e-06	193	193	8	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DNAH14 CADM1 BICC1 MACC1 OXR1 FHOD3 LRBA	2.16e-06	194	193	8	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM DNAH14 BICC1 MACC1 OXR1 FHOD3 PARD3 PCCA	2.16e-06	194	193	8	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 SORT1 CADM1 FBXO34 MACC1 UNC13C LRBA	2.16e-06	194	193	8	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MECOM CADM1 DLC1 PTPRK LIMCH1 USP54 PARD3	2.16e-06	194	193	8	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	MECOM C8orf34 CADM1 PTPRK KLF5 LIMCH1 USP54 PARD3	2.24e-06	195	193	8	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	HDAC9 MECOM CADM1 KLF5 NRK BICC1 OXR1 MYOF	2.33e-06	196	193	8	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DLC1 PCDH18 BICC1 ZFHX4 FRMD6 LRP1 DAAM2 UNC13C	2.42e-06	197	193	8	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DLC1 PCDH18 BICC1 ZFHX4 FRMD6 LRP1 DAAM2 UNC13C	2.42e-06	197	193	8	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	DLC1 PCDH18 BICC1 ZFHX4 FRMD6 LRP1 DAAM2 UNC13C	2.42e-06	197	193	8	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA CADM1 PTPRK PTPRN2 KLF5 WNK2 MUC16 LIMCH1	2.71e-06	200	193	8	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD2 HEPH NR1I2 SEMA3B NR1I3 APOB UGT1A1	3.68e-06	147	193	7	a5ed71afe5fcb4f541080f5552252695c7d4d090
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4C SEMA3G WNK2 FHOD3 SLC5A5 DAAM2 UNC13C	5.92e-06	158	193	7	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4C SEMA3G WNK2 FHOD3 SLC5A5 DAAM2 UNC13C	5.92e-06	158	193	7	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HEPH FBXL7 PTPRB SEC14L4 FRMD6 ELK3 SMAD1	7.55e-06	164	193	7	a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HEPH FBXL7 PTPRB SEC14L4 FRMD6 ELK3 SMAD1	7.55e-06	164	193	7	1a1795969673232191425dde84ab24ee6a98143f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HEPH FBXL7 PTPRB SEC14L4 FRMD6 ELK3 SMAD1	7.55e-06	164	193	7	8f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	MECOM CADM1 DLC1 SERPINE1 LIMCH1 USP54 PARD3	9.55e-06	170	193	7	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 CYP2J2 MYO18B MTUS2 WNK2 FLNC FHOD3	9.55e-06	170	193	7	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	(03)_Secretory-(0)_uninjured\|(03)_Secretory / shred by cell type and Timepoint	GDPD2 CHAD CADM1 ST8SIA6 SEC14L4 MUC16 SEC14L3	1.11e-05	174	193	7	ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYN3 FBXL7 DLC1 MYOF FRMD6 SERPINE1 LRP1	1.20e-05	176	193	7	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYN3 FBXL7 DLC1 MYOF FRMD6 SERPINE1 LRP1	1.20e-05	176	193	7	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HDAC9 CYP2J2 SORT1 MYO18B MTUS2 FLNC FHOD3	1.20e-05	176	193	7	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DHX38 GATM GAB2 SORT1 STIL MYOF LRP1	1.20e-05	176	193	7	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	HEPH DLC1 BICC1 FRMD6 PCDHGA12 SERPINE1 LRP1	1.29e-05	178	193	7	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	FBXL7 PTPRB FLNC ZFHX4 FRMD6 ELK3 SMAD1	1.29e-05	178	193	7	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 C8orf34 NFKB1 BCAR3 OXR1 FHOD3 PARD3	1.29e-05	178	193	7	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	MECOM CADM1 SEMA3B MACC1 LIMCH1 USP54 PARD3	1.34e-05	179	193	7	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 CADM1 NRK BCAR3 FHOD3 LIMCH1	1.34e-05	179	193	7	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	ACACA MECOM C8orf34 CADM1 DLC1 PTPRK LIMCH1	1.38e-05	180	193	7	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	SYN3 LGALS14 SEMA3G FBXL7 PTPRB ST8SIA6 SERPINE1	1.43e-05	181	193	7	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ACACA MECOM DNAH14 CADM1 KLF5 MACC1 MYOF	1.43e-05	181	193	7	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C8orf34 BICC1 CNTN4 MACC1 OXR1 MAML2 PARD3	1.43e-05	181	193	7	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM CADM1 SEMA3B BCAR3 SLC27A5 CHST3 IGSF21	1.54e-05	183	193	7	876b4f128c2168fdae7488201ff44f19c06c8415
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATM CADM1 SEMA3B BCAR3 SLC27A5 CHST3 IGSF21	1.54e-05	183	193	7	b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM TBC1D9 CADM1 NRK FHOD3 UNC13C LIMCH1	1.54e-05	183	193	7	2e831a4d99c6f983793df71c0994124c943c6da9
Disease	age at menarche	FAM120B NXPE2 GAB2 CADM1 PTPRK PTPRN2 HACE1 UNC79 SLC27A5 ZFHX4 EIF4G1 GAN UNC13C RERE	2.52e-05	594	185	14	EFO_0004703
Disease	cell adhesion molecule 1 measurement	NXPE2 CADM1	3.91e-05	2	185	2	EFO_0020251
Disease	Colorectal Carcinoma	ABCA4 ACACA OTOP2 C8orf34 DLC1 PTPRN2 KLF5 CNTN4 FLNC PARP8 APOB CSE1L EIF4G1 LRP1 IGSF21	3.98e-05	702	185	15	C0009402
Disease	fatty liver disease (implicated_via_orthology)	ACACA ACACB NFKB1 LRP6	4.12e-05	31	185	4	DOID:9452 (implicated_via_orthology)
Disease	intraocular pressure measurement	ABCA4 SYN3 MYOC OTOP2 MECOM GAB2 DLC1 KLF5 HERC2 BICC1 MYOF DAAM2	9.62e-05	509	185	12	EFO_0004695
Disease	COVID-19 symptoms measurement, COVID-19	NXPE2 CADM1	1.17e-04	3	185	2	EFO_0600019, MONDO_0100096
Disease	amygdala volume change measurement	PKD1L1 EMB PARP8	1.28e-04	16	185	3	EFO_0021490
Disease	uric acid measurement	SYN3 PCNX3 MECOM DDX1 NFKB1 BICC1 SLC27A5 PRRC2B CNTN4 POLR1A MYOF UNC5CL SENP2	1.35e-04	610	185	13	EFO_0004761
Disease	coronary artery disease	HDAC9 SYN3 PCNX3 WDR33 CETP DHX38 MECOM C8orf34 DLC1 PCDH18 BICC1 WNK2 ABCC10 CHST3 EMB PARP8 APOB RSBN1 LRP1	1.95e-04	1194	185	19	EFO_0001645
Disease	syndromic X-linked intellectual disability (is_implicated_in)	HNRNPH2 TAF1	2.33e-04	4	185	2	DOID:0060309 (is_implicated_in)
Disease	mean platelet volume	HDAC9 AOC1 PCNX3 MECOM EHD3 ATAD2B DDX39B FBXO34 PCDHGA7 U2SURP SIK3 STIL TERT RSBN1 PCDHGA12 MAML2 PCDHGA8	2.51e-04	1020	185	17	EFO_0004584
Disease	amino acid measurement	ACACB CYP2J2 NXPE2 CADM1 PTPRB PTPRN2 SUN2 MTUS2 WNK2 GAN UNC13C PRKDC LRBA	3.73e-04	678	185	13	EFO_0005134
Disease	pulse pressure measurement, unipolar depression	NXPE2 CADM1	3.86e-04	5	185	2	EFO_0003761, EFO_0005763
Disease	migraine disorder, type 1 diabetes mellitus	FOXI3 RERE	3.86e-04	5	185	2	MONDO_0005147, MONDO_0005277
Disease	muscular disease (implicated_via_orthology)	ACACA ACACB	3.86e-04	5	185	2	DOID:0080000 (implicated_via_orthology)
Disease	cholesterol to total lipids in large LDL percentage	CETP R3HDML APOB SIK3	4.26e-04	56	185	4	EFO_0022235
Disease	urate measurement	PDE4C PCNX3 DHX38 MECOM DDX1 MYO18B BICC1 FBXO34 PRRC2B U2SURP SEC14L3 UNC5CL AP5B1 LRP1 SENP2	5.50e-04	895	185	15	EFO_0004531
Disease	diabetes mellitus (implicated_via_orthology)	PTPRN2 SERPINE1 LRP1	5.67e-04	26	185	3	DOID:9351 (implicated_via_orthology)
Disease	familial combined hyperlipidemia (is_marker_for)	APOB SERPINE1	5.77e-04	6	185	2	DOID:13809 (is_marker_for)
Disease	alkaline phosphatase measurement	CYP2A7 PDE4C AOC1 ACACB DHX38 ABCC10 RIC1 MACC1 RAP1GAP U2SURP APOB RSBN1 YKT6 UNC13C LRBA SNRPA	6.97e-04	1015	185	16	EFO_0004533
Disease	response to angiotensin receptor blocker	BICC1 MACC1 POLR1A	8.69e-04	30	185	3	EFO_0010735
Disease	basophil percentage of leukocytes	LGALS14 HELB NFKB1 CNTN4 RSBN1 PRKDC DNPEP	8.94e-04	243	185	7	EFO_0007992
Disease	apolipoprotein A 1 measurement	CYP2A7 AOC1 ACACB CETP DHX38 ADAR NR1I2 DLC1 UGT2B10 OR8J2 APOB SIK3 SEC14L6 LRP1	9.71e-04	848	185	14	EFO_0004614
Disease	childhood trauma measurement, alcohol consumption measurement	C8orf34 PCDHGA7 PCDHGA12 PCDHGA8	1.05e-03	71	185	4	EFO_0007878, EFO_0007979
Disease	phenol sulfate measurement	CYP2J2 MYO18B	1.07e-03	8	185	2	EFO_0021011
Disease	Lymphoid leukemia	MECOM TERT	1.07e-03	8	185	2	C0023448
Disease	chylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	CETP APOB SIK3	1.26e-03	34	185	3	EFO_0008317, EFO_0008596, EFO_0020947
Disease	ureteral obstruction (implicated_via_orthology)	CYP2J2 SERPINE1	1.37e-03	9	185	2	DOID:5199 (implicated_via_orthology)
Disease	Thyroid Gland Follicular Adenoma	RAP1GAP TERT SLC5A5	1.37e-03	35	185	3	C0151468
Disease	Cardiovascular Diseases	CETP SORT1 APOB	1.49e-03	36	185	3	C0007222
Disease	cholesteryl esters to total lipids in very large HDL percentage	CETP APOB SIK3	1.49e-03	36	185	3	EFO_0022257
Disease	colorectal cancer	C8orf34 PTPRN2 KLF5 HERC2 BICC1 SLC27A5 CHST3 TERT LRP1 PCNX1 LRBA	1.58e-03	604	185	11	MONDO_0005575
Disease	ovarian neoplasm	MECOM DLC1 MUC16 TERT SLC5A5	1.60e-03	134	185	5	C0919267
Disease	Thyroid Neoplasm	RAP1GAP TERT SLC5A5	1.61e-03	37	185	3	C0040136
Disease	cholesteryl esters to total lipids in medium LDL percentage	CETP APOB SIK3	1.61e-03	37	185	3	EFO_0022252
Disease	level of Triacylglycerol (51:3) in blood serum	APOB SIK3	1.70e-03	10	185	2	OBA_2045163
Disease	abdominal aortic calcification measurement	HDAC9 RAP1GAP	1.70e-03	10	185	2	EFO_0010272
Disease	Malignant neoplasm of ovary	MECOM DLC1 MUC16 TERT SLC5A5	1.76e-03	137	185	5	C1140680
Disease	cortical thickness	HDAC9 ABCA4 MECOM STAU1 FBXL7 DLC1 CDH20 XPO5 NFKB1 WNK2 ABCC10 LRP1 RERE PARD3 PCCA ANKFN1	1.81e-03	1113	185	16	EFO_0004840
Disease	lung non-small cell carcinoma (is_implicated_in)	PTPRB XPO5 NFKB1 TERT UGT1A1	1.87e-03	139	185	5	DOID:3908 (is_implicated_in)
Disease	Parkinson disease, disease progression measurement	NXPE2 CADM1 PARD3	1.88e-03	39	185	3	EFO_0008336, MONDO_0005180
Disease	lobe attachment	HDAC9 NPVF SIK3 DAAM2 PRKDC LRBA	2.01e-03	207	185	6	EFO_0007667
Disease	anti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine	ADA2 FHOD3	2.07e-03	11	185	2	EFO_0803358, EFO_0803362
Disease	triacylglycerol 56:2 measurement	ZFHX4 LIMCH1	2.07e-03	11	185	2	EFO_0010429
Disease	beta thalassemia (is_marker_for)	APOB TERT	2.07e-03	11	185	2	DOID:12241 (is_marker_for)
Disease	maleate measurement, Alpha ketoglutarate measurement, fumarate measurement	EMB PARP8	2.07e-03	11	185	2	EFO_0010457, EFO_0010480, EFO_0010509
Disease	level of Diacylglycerol (18:1_18:1) in blood serum	APOB SIK3	2.07e-03	11	185	2	OBA_2045170
Disease	blood urea nitrogen measurement	MECOM DDX1 CDH20 BCAR3 BICC1 ABCC10 AP5B1 SENP2 LRBA	2.31e-03	452	185	9	EFO_0004741
Disease	cholesteryl esters to total lipids in small LDL percentage	CETP APOB SIK3	2.33e-03	42	185	3	EFO_0022255
Disease	integral membrane protein 2B measurement	CETP APOB	2.48e-03	12	185	2	EFO_0802634
Disease	Myeloproliferative disease	MECOM TERT	2.48e-03	12	185	2	C0027022
Disease	cholesteryl esters to total lipids in small HDL percentage	CETP APOB SIK3	2.49e-03	43	185	3	EFO_0022254
Disease	free cholesterol to total lipids in very small VLDL percentage	CETP APOB SIK3	2.49e-03	43	185	3	EFO_0022290
Disease	immunoglobulin isotype switching measurement	EMB PARP8 SEC14L3	2.66e-03	44	185	3	EFO_0010128
Disease	Thyroid carcinoma	RAP1GAP TERT SLC5A5	2.66e-03	44	185	3	C0549473
Disease	smoking status measurement	ADAR GAB2 SYNGAP1 DLC1 PTPRK PTPRN2 HACE1 UNC79 PRRC2B CNTN4 POLR1A TCF20 SERPINE1 RERE PCCA IGSF21	2.72e-03	1160	185	16	EFO_0006527
Disease	autism spectrum disorder (implicated_via_orthology)	SYN3 TSC1 SYNGAP1 TCF20 LRBA	2.76e-03	152	185	5	DOID:0060041 (implicated_via_orthology)
Disease	Common variable immunodeficiency	NFKB1 LRBA	2.91e-03	13	185	2	cv:C0009447
Disease	complement component C6 measurement	EMB PARP8	2.91e-03	13	185	2	EFO_0020281
Disease	Hyperlipoproteinemia Type IIb	CETP APOB	2.91e-03	13	185	2	C1704417
Disease	triacylglycerol 54:4 measurement	MTUS2 APOB SIK3	3.02e-03	46	185	3	EFO_0010422
Disease	Adenocarcinoma of large intestine	DLC1 NRK TAF1 PRKDC	3.17e-03	96	185	4	C1319315
Disease	Neuroblastoma	HACE1 SEMA3B TERT	3.21e-03	47	185	3	C0027819
Disease	Malignant neoplasm of breast	ABCA4 MAN2C1 MECOM ADAR CADM1 CDH20 BCAR3 HERC2 RAP1GAP SIK3 TERT SLC5A5 ELK3 USP54 LRBA	3.28e-03	1074	185	15	C0006142
Disease	lymphocyte percentage of leukocytes	HDAC9 AOC1 EHD3 NR1I2 KLF5 NFKB1 HELZ TERT PRKDC RERE DNPEP	3.31e-03	665	185	11	EFO_0007993
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	BICC1 FLNC	3.39e-03	14	185	2	DOID:898 (implicated_via_orthology)
Disease	phoneme awareness	STAU1 CSE1L	3.39e-03	14	185	2	EFO_0021812
Disease	schizophrenia, anorexia nervosa	CADM1 CNTN4 RERE	3.41e-03	48	185	3	MONDO_0005090, MONDO_0005351
Disease	total lipids in lipoprotein particles measurement	CETP DHX38 APOB	3.41e-03	48	185	3	EFO_0022309
Disease	ceramide measurement	HDAC9 MDN1 POLR1A OXR1 APOB SEC14L6	3.77e-03	235	185	6	EFO_0010222
Disease	triglycerides to total lipids in medium LDL percentage	CETP APOB SIK3	3.83e-03	50	185	3	EFO_0022334
Disease	polyunsaturated fatty acids to total fatty acids percentage	CETP APOB SIK3	3.83e-03	50	185	3	EFO_0022303
Disease	mouth morphology measurement	HDAC9 OXR1 PCCA	3.83e-03	50	185	3	EFO_0007955
Disease	Proteinuria	UNC13C SAMD3	3.89e-03	15	185	2	HP_0000093
Disease	triacylglycerol 52:3 measurement	APOB SIK3	3.89e-03	15	185	2	EFO_0010415
Disease	triglycerides to total lipids in chylomicrons and extremely large VLDL percentage	CETP APOB	3.89e-03	15	185	2	EFO_0022328
Disease	Hypertriglyceridemia	CETP APOB	3.89e-03	15	185	2	C0020557
Disease	chronotype measurement	NXPE2 SYNGAP1 CADM1 FIG4 KLF5 ATAD2B SCN8A BICC1 ABCC10 CNTN4 TCF20 RERE ANKFN1	3.89e-03	882	185	13	EFO_0008328
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	CETP APOB SIK3	4.05e-03	51	185	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	phospholipids in very small VLDL measurement	CETP APOB SIK3	4.05e-03	51	185	3	EFO_0022300
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	CETP APOB SIK3	4.05e-03	51	185	3	EFO_0022302
Disease	cholesterol to total lipids in small HDL percentage	CETP APOB SIK3	4.05e-03	51	185	3	EFO_0022240
Disease	creatinine measurement	GATM MECOM DDX1 GAB2 DLC1 CDH20 NFKB1 BCAR3 RNF128 ABCC10 AP5B1 SENP2 PARD3 IGSF21	4.18e-03	995	185	14	EFO_0004518
Disease	basophil count, eosinophil count	LGALS14 NFKB1 SIK3 PRKDC RERE DNPEP	4.26e-03	241	185	6	EFO_0004842, EFO_0005090
Disease	ovarian carcinoma	ABCA4 PKD1L1 MECOM DLC1 PTPRN2 MTUS2 TERT	4.28e-03	321	185	7	EFO_0001075
Disease	phospholipids in medium VLDL measurement	CETP APOB SIK3	4.28e-03	52	185	3	EFO_0022154
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	MECOM TERT PARD3	4.28e-03	52	185	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	Hyperlipoproteinemia Type IIa	CETP APOB	4.43e-03	16	185	2	C0745103
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	HDAC9 SERPINE1	4.43e-03	16	185	2	EFO_0004792, HP_0002140
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TSC1 BICC1	4.43e-03	16	185	2	DOID:0110861 (implicated_via_orthology)
Disease	triglycerides in HDL measurement	CETP APOB SIK3	4.51e-03	53	185	3	EFO_0022317
Disease	free cholesterol to total lipids in small LDL percentage	CETP APOB SIK3	4.51e-03	53	185	3	EFO_0022286
Disease	cholesteryl esters to total lipids in very large VLDL percentage	CETP APOB SIK3	4.51e-03	53	185	3	EFO_0022258
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement	ACACB CETP APOB SIK3	4.52e-03	106	185	4	EFO_0008317, EFO_0008596
Disease	total lipids in medium VLDL	CETP APOB SIK3	4.76e-03	54	185	3	EFO_0022153
Disease	triglycerides in medium HDL measurement	CETP APOB SIK3	4.76e-03	54	185	3	EFO_0022321
Disease	cholesterol to total lipids in very large VLDL percentage	CETP APOB SIK3	4.76e-03	54	185	3	EFO_0022244
Disease	hepatocellular carcinoma (biomarker_via_orthology)	SF3B4 CADM1 NFKB1 TERT	4.83e-03	108	185	4	DOID:684 (biomarker_via_orthology)
Disease	melanoma	GAB2 PTPRK UGT2B10 RAP1GAP TERT SLC5A5	4.89e-03	248	185	6	C0025202
Disease	Lipidemias	CETP APOB	5.00e-03	17	185	2	C1706412

Protein segments in the cluster

Peptide	Gene	Start	Entry
SIQNLPEEMQPHFFK	ACTR6	301	Q9GZN1
VMVKFLFPRPDQQHS	CETP	361	P11597
MFLLTSPQYHPLPQD	nan	566	Q9N2K0
NENFGPNTEMHLVPI	DNPEP	186	Q9ULA0
LIHMDQNFGNRPVTP	CYP2J2	101	P51589
QNFGNRPVTPMREHI	CYP2J2	106	P51589
SPRIQEFIHRPSMQD	ABCA4	281	P78363
FASLPRNMPVNHQFP	BCAR3	6	O75815
NFPAIAIHRGMPQEE	DDX39B	311	Q13838
VLIIFHNPSLRAPMF	GPR12	66	P47775
QQLLEPQQYMAFLPH	FBXO34	566	Q9NWN3
PMASHPQTRIQAYLE	C8orf34	86	Q49A92
PDNHSPITMYVIQAR	CNTN4	621	Q8IWV2
NHIFLNFVPTVIMDP	ACACA	1471	Q13085
MPTGVPLRRHFNSNF	AOC1	421	P19801
NNFPVLAANSFRAMP	CHAD	61	O15335
MQRTGAQIHFPDPSN	BICC1	311	Q9H694
PQMLRLNADPHFFTQ	CDK5R2	306	Q13319
GMQNSLPRNFFLHPV	DISP1	1346	Q96F81
PGHPFSQMSEKFLQE	MTUS2	721	Q5JR59
SHLIFPQPNYVDMLI	PCDHGA7	766	Q9Y5G6
FYLTPNSPAEMLHNV	PARVG	261	Q9HBI0
QVLQEVSMSRYIPHP	RIC1	626	Q4ADV7
SHLIFPQPNYADMLI	PCDHGA8	766	Q9Y5G5
SHLIFPQPNYADMLV	PCDHGA12	766	O60330
IMDHDPRNPAYIATQ	PTPRN2	806	Q92932
SMLHQGQYQPRPSFR	PCDH18	836	Q9HCL0
SPGFLFHPQMSAIEN	MECOM	851	Q03112
VEFQFMLPSSHPNRM	ACACB	1321	O00763
GTMFEQFVQFRPPAH	NR1I3	126	Q14994
HPLQFMEFSSPIPNA	DAAM2	31	Q86T65
MFLPNDTQFHPSSFL	OR52E2	1	Q8NGJ4
FLGPSMARQPNILVH	MUC16	3056	Q8WXI7
HRVLMAPVTFFNATP	ABCC10	1006	Q5T3U5
IQLLFNDMKVFPPFH	PTPRB	851	P23467
NDMKVFPPFHLVNTA	PTPRB	856	P23467
FVYTRPHPNSQMDKF	OR4F21	256	O95013
PVNRQLKFMHTPHQF	PARP8	656	Q8N3A8
PFHNFSMVNSLIYPR	FOXI3	401	A8MTJ6
QEIHSRLMGPQAYPV	MDN1	4261	Q9NU22
FKDPNPMHIDATFNI	GATM	296	P50440
VAFNVNNLPFTEPML	HERC2	2266	O95714
QPFDLQVYHPSRQPM	LRP1	1521	Q07954
FFQELILNQASMAPP	ATAD2B	906	Q9ULI0
QPHTNENREIMKPFF	FSIP2	3346	Q5CZC0
FEIPPHMKNQALFPA	DDX1	216	Q92499
YNFFSPLNPMRVHIE	HNRNPH2	306	P55795
AQPFAVPHSAMLFIQ	PCNX1	1476	Q96RV3
PFAVPHSAMLFVQAL	PCNX3	1266	Q9H6A9
SAPPFVHIIMANVFL	OR51F2	281	Q8NH61
IMQAPVPHSQRRESF	PDE4C	106	Q08493
DRFQVPTAHSEMQPL	FAM219A	6	Q8IW50
FHPRPNFRQMKLENV	FLNC	86	Q14315
QINAFLQGFHMFIPP	HACE1	756	Q8IYU2
LQGFHMFIPPSLIQL	HACE1	761	Q8IYU2
QFMQGYPSKVHILPR	MYOC	306	Q99972
PILTQFTPYLGHMRN	PRAMEF15	221	P0DUQ1
EHPNSMIPAFDQRNG	LRBA	706	P50851
FSPMDIHAFSQQRQP	LRP6	266	O75581
SIMFDLRRPPQNHTY	GDPD2	351	Q9HCC8
AQLYQARPMLAPHFV	AP5B1	491	Q2VPB7
DIHPFATPLMQELFG	NR1I2	416	O75469
QHFQENSRMPVIKPD	PCCA	541	P05165
NYSVLQHLGQFPPLM	HELZ	1856	P42694
PEMVGHPAFAVIFQL	NPHP4	346	O75161
IFNSPLEAAMAFPHL	SMPD4	31	Q9NXE4
LEAAMAFPHLQQPSF	SMPD4	36	Q9NXE4
TDSRLQTPMYFFPQH	OR5AK3P	51	Q8NH89
FHSVFNPMLNPLIYS	OR2A2	276	Q6IF42
IDPQLHTPMYFLLSQ	OR2AE1	51	Q8NHA4
FQNMFIIESLHRGPP	OTOP2	416	Q7RTS6
VDPQLQTPMYFFLRH	OR8J2	51	Q8NGG1
DLSRSFINNPHPAME	MAML2	536	Q8IZL2
GVLLVTPNNIMFDPH	OXR1	231	Q8N573
VQYRMHPALSAFPSN	UPF1	711	Q92900
EMPQHAVLSGPNLFI	CADM1	286	Q9BY67
DQFGPPMIIHFRVQY	FRMD6	101	Q96NE9
HADPPVQILYNRTMV	EIF3CL	601	B5ME19
FNLQNMGLPDFHIPE	APOB	1261	P04114
VYSGPHPQREMLTAQ	FAM126A	161	Q9BYI3
ILVHGFQNEVFPEPM	IGSF21	361	Q96ID5
HFMPPELLQSQFETL	IDNK	141	Q5T6J7
NYQVLPFRQHEMQSP	KLHL26	286	Q53HC5
FNMIEQSGPPHEPRF	ADAR	521	P55265
PRYIPQKQSEDMHAF	GNPAT	351	O15228
PHNFNRFPPRFMQDD	CHERP	541	Q8IWX8
RLPDHSMVQIFSFLP	FBXL7	116	Q9UJT9
NMIYIPNDSVRVTHP	FIG4	131	Q92562
ANPHLEMRFLNLGPF	CDH20	356	Q9HBT6
PNSPQDFIDSFLIHM	CYP2A7	261	P20853
FINHMTQAIPFDDPR	FRMPD4	51	Q14CM0
NVLRFHFMSPPPAQS	DHX35	441	Q9H5Z1
ALPPMNEARHNFGIV	GAN	356	Q9H2C0
FMGHPPYAIREVNIN	FHOD3	1226	Q2V2M9
PSRFHFQGQAPQVMK	DIDO1	2006	Q9BTC0
RTLIFPPSMHFFQAK	ADA2	76	Q9NZK5
NPHFLPSVYNFVTMI	DNAH14	2591	Q0VDD8
STLFQFPTLLNGHMP	ELK3	371	P41970
QFIFASMQKPEGLPH	EIF4G1	621	Q04637
FQEVSLRAFLDPPHM	MACC1	246	Q6ZN28
PDTFGYSAQLPQIMH	MAN2C1	371	Q9NTJ4
NPLQRNEMGHTPLDY	CLPB	291	Q9H078
GNMPPFLRYLTTQLH	ENGASE	246	Q8NFI3
FTSPPLREEIMANNF	EMB	41	Q6PCB8
FMQQPFLEPTHTRAL	HDAC9	571	Q9UKV0
VLPSQRYNAHMVPED	SEC14L3	336	Q9UDX4
VLPSQRYNAHMVPED	SEC14L4	336	Q9UDX3
VLPSQRYNAHMVPED	SEC14L6	336	B5MCN3
HPPVAILARNSDNFM	PKD1L1	276	Q8TDX9
NTIPFRNVMTALQFP	HELB	201	Q8NG08
NHIRASVYPPAANME	R3HDML	71	Q9H3Y0
SHKEQPGRNMFFIPS	FAM120B	121	Q96EK7
TFPFLDKMPEANQLH	LIMCH1	726	Q9UPQ0
FPALTFLNNHDQPFM	LGSN	226	Q5TDP6
PLEQFPHSMEPQLRQ	MRTO4	141	Q9UKD2
PLSITFMDQHNFSPR	PTPRK	816	Q15262
FHPRELNAEPSQMQI	PARD3	551	Q8TEW0
FDPSMLLQRFSVAPH	RNF180	286	Q86T96
IMDRPFLFVVRHNPT	SERPINE1	376	P05121
RPFFSSNPELDNLMI	MEIS3P1	36	A6NDR6
FVYTRPHPNSQMDKF	OR4F3;	256	Q6IEY1
RASVYMQPPIDGQAH	FAM83G	146	A6ND36
RPTSANMLQHPFVRD	NRK	301	Q7Z2Y5
QPTLFTFEPPVSNHM	GAB2	166	Q9UQC2
EYRVPQGVQTPFMTH	RSBN1	326	Q5VWQ0
VEQTFFPNHKPMVTA	SYN3	226	O14994
RDKPITFTQHQMPLF	SENP2	561	Q9HC62
NFVQTDLPFHPLTQM	SORT1	206	Q99523
FLPMLNRQDPFTVHM	ATP6V1H	126	Q9UI12
MPFGLHRQFPENSLQ	POLR1A	881	O95602
PATFINMYNRPIHIT	TEX47	226	Q8TBZ9
HPPDYVIQNQIGMFL	NXPE2	541	Q96DL1
RHGEQMPSFYPAENL	SAMD3	101	Q8N6K7
MRDLPNTYPFHTPVN	TAF1	1396	P21675
QISPQLHTPMYFFLS	OR5AL1	66	P0C617
VFYNRASQPFSMQPH	HEPH	471	Q9BQS7
PILTQFTPYLGHMRN	PRAMEF25	221	A6NGN4
LQLHLPMNFTSYIVP	PRSS47P	176	A8MTI9
FNFPGTRNEVIPMSH	RNF128	146	Q8TEB7
NTPFVPDMIASNFLH	RAP1GAP	301	P47736
QAPFLQVAPNVNFMH	SIK3	496	Q9Y2K2
KNIFHMFPVSQPFVD	ST8SIA6	166	P61647
PILTQFTPYLGHMRN	PRAMEF27	221	A3QJZ7
NVRVNYDFGPIHMPL	RNF216	836	Q9NWF9
SDPLARLQMFNVTPH	RERE	1411	Q9P2R6
MSIPFSNTHYRIPQG	SPA17	1	Q15506
QNSMAPHPARDYVVL	DLC1	1416	Q96QB1
HQISPGDFPNLKRMQ	EHD3	346	Q9NZN3
FRNLGQNEPHMPLNA	SMAD1	156	Q15797
PLEQATQFSAFLLPM	SRPK3	531	Q9UPE1
NPMFRFLFENQTPAH	U2SURP	456	O15042
TPHSGFLNLPLQMFE	ANKFN1	741	Q8N957
FITPLPEDHLTQFMF	CHST3	206	Q7LGC8
HLSRYQNPREADPMT	YKT6	126	O15498
GALIRPLPSQQMFEH	TMX3	131	Q96JJ7
PILTQFTPYLGHMRN	PRAMEF4	221	O60810
RMFASLFPHNPQFIG	RPF1	261	Q9H9Y2
QMNTRFPSSRMVPFH	STIL	11	Q15468
HFPMTPEALLQFQQP	ZFHX4	1676	Q86UP3
PIFMLHFVEGLPQND	USPL1	416	Q5W0Q7
PMIPQSGKQHLLDFF	TSC1	141	Q92574
QGFYLLNSIIEHMPP	CSE1L	746	P55060
PSIGFMNKIFHPNID	UBE2H	66	P62256
QALIYPMSSTIPHNF	UNC13C	1086	Q8NB66
MPHSFANLPLRFGRN	NPVF	81	Q9HCQ7
GEPIQTFHFQAPTMA	SUN2	671	Q9UH99
DEFRMPYLSHQQLPA	STAU1	401	O95793
LRIPLSFQNPLFHMA	SYNGAP1	921	Q96PV0
HSRINLMDFNPDPRS	SLC5A5	226	Q92911
PAYATPHFIRIQDAM	SLC27A5	621	Q9Y2P5
ISMNLVPFPQLHYLV	TUBE1	286	Q9UJT0
FARNHPLMYNSVLPT	SEMA3B	401	Q13214
RQFPLHEMFVSPQGH	TBC1D10C	141	Q8IV04
PILTQFTPYLGHMRN	PRAMEF9	221	P0DUQ2
QPRTQKFFEMIENHP	UBE4B	946	O95155
VAEMPQNYRPHPQRF	TRIM25	481	Q14258
RSLPEHPAFQNEMGI	TBC1D9	566	Q6ZT07
PQNDLLGHPMTRAFI	UGT1A1	356	P22309
RQHLPATLPEMVAFY	UNC5CL	66	Q8IV45
PLMAVPARYGFNSHQ	ZDBF2	2106	Q9HCK1
PQLVLPNFDMLYNHV	XPO5	616	Q9HAV4
LQPFRSQVYMHPSLS	PRRC2B	1991	Q5JSZ5
PMTPQFEHVLAVGNL	SCN8A	776	Q9UQD0
RVPQAAQLHSVAMPF	SCART1	731	Q4G0T1
LGVQDLLQFHFMDPP	DHX38	901	Q92620
EVPVRSPMQFHQNFS	TCF20	351	Q9UGU0
IMVVDSPGFQNPRHQ	MYO18B	941	Q8IUG5
QLIVAHFPMQSREFP	PRKDC	1716	P78527
NFAHRFPPASVKMLQ	LGALS14	111	Q8TCE9
MFDHPIPRVFQNRFS	UFD1	6	Q92890
GIPLFFDQPDNIAHM	UGT2B10	391	P36537
AVGHLPFQPDMVSQL	ZNF227	61	Q86WZ6
PDEVLQFARAHPLMF	SEMA3G	401	Q9NS98
FFHMPRFQHQAPRQL	WDR33	11	Q9C0J8
QQHFPDPAMSFAPVL	WNK2	696	Q9Y3S1
MAVPETRPNHTIYIN	SNRPA	1	P09012
ELFLQAGPVVNTHMP	SF3B4	31	Q15427
PYMRQFVAHLQETSP	TERT	771	O14746
FNPHPSRFMDLDELQ	USP54	771	Q70EL1
RRVQHNMLSPFHSPF	UNC79	746	Q9P2D8
PYSINMNVFLPDITH	KLF5	131	Q13887
DHYIPNTLNPVFGRM	MYOF	1591	Q9NZM1
LTHTIFNPEVFQPQM	NFKB1	21	P19838