Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNotch binding

JAG2 SNED1 DNER DLL1 NOTCH4

9.30e-0827855GO:0005112
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 SNED1 HSPG2 CELSR1 THBS4 CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

3.11e-067498514GO:0005509
GeneOntologyCellularComponentextracellular matrix

SNED1 HSPG2 LAMB4 THBS4 ZAN CFP LTBP3 LTBP4 SSPOP SCARA3

3.93e-046568710GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SNED1 HSPG2 LAMB4 THBS4 ZAN CFP LTBP3 LTBP4 SSPOP SCARA3

4.03e-046588710GO:0030312
MousePhenoabnormal direction of embryo turning

MEGF8 DLL1 INVS

2.65e-0513653MP:0004190
MousePhenoabnormal direction of heart looping

C2CD3 MEGF8 DLL1 INVS

2.79e-0538654MP:0004252
DomainEGF_2

SCARF1 JAG2 SNED1 HSPG2 LAMB4 CELSR1 THBS4 ZAN CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 SSPOP MEGF11 NOTCH3 NOTCH4 EPHA8

3.28e-192658520PS01186
DomainEGF_1

SCARF1 JAG2 SNED1 HSPG2 LAMB4 CELSR1 THBS4 ZAN CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 SSPOP MEGF11 NOTCH3 NOTCH4

3.61e-182558519PS00022
DomainEGF-like_CS

SCARF1 JAG2 SNED1 HSPG2 LAMB4 CELSR1 THBS4 ZAN CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 MEGF11 NOTCH3 NOTCH4 EPHA8

5.59e-182618519IPR013032
DomainEGF_3

SCARF1 JAG2 SNED1 HSPG2 CELSR1 THBS4 ZAN CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 SSPOP MEGF11 NOTCH3 NOTCH4

1.85e-172358518PS50026
DomainEGF_CA

JAG2 SNED1 HSPG2 CELSR1 THBS4 CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

3.08e-161228514SM00179
DomainEGF-like_Ca-bd_dom

JAG2 SNED1 HSPG2 CELSR1 THBS4 CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

3.89e-161248514IPR001881
DomainEGF

SCARF1 JAG2 SNED1 HSPG2 CELSR1 THBS4 ZAN CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 MEGF11 NOTCH3 NOTCH4

4.15e-162358517SM00181
DomainEGF-like_dom

SCARF1 JAG2 SNED1 HSPG2 CELSR1 THBS4 ZAN CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 MEGF11 NOTCH3 NOTCH4

1.09e-152498517IPR000742
DomainASX_HYDROXYL

JAG2 SNED1 CELSR1 CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

2.68e-141008512PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 SNED1 CELSR1 CELSR3 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

5.50e-141068512IPR000152
DomainGrowth_fac_rcpt_

SCARF1 JAG2 HSPG2 CELSR1 THBS4 IGFBP4 MEGF8 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

2.56e-131568513IPR009030
DomainhEGF

JAG2 SNED1 DNER LTBP3 DLL1 MEGF11 NOTCH3 NOTCH4

3.79e-1328858PF12661
DomainEGF_Ca-bd_CS

JAG2 SNED1 THBS4 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

6.44e-13978511IPR018097
DomainEGF_CA

JAG2 SNED1 THBS4 MEGF8 FAT3 DNER LTBP3 DLL1 LTBP4 NOTCH3 NOTCH4

8.10e-13998511PS01187
DomainEGF

JAG2 SNED1 HSPG2 CELSR1 THBS4 ZAN CELSR3 DNER DLL1 NOTCH3 NOTCH4

1.18e-111268511PF00008
DomainLaminin_EGF

SCARF1 HSPG2 LAMB4 CELSR1 CELSR3 MEGF8 MEGF11

1.91e-1035857PF00053
DomainLaminin_EGF

SCARF1 HSPG2 LAMB4 CELSR1 CELSR3 MEGF8 MEGF11

3.54e-1038857IPR002049
DomainEGF_CA

JAG2 THBS4 MEGF8 FAT3 LTBP3 LTBP4 NOTCH3 NOTCH4

5.23e-0986858PF07645
DomainEGF_Lam

HSPG2 LAMB4 CELSR1 CELSR3 MEGF8 MEGF11

1.08e-0835856SM00180
DomainEGF_LAM_2

HSPG2 LAMB4 CELSR1 CELSR3 MEGF8

2.26e-0730855PS50027
DomainEGF_LAM_1

HSPG2 LAMB4 CELSR1 CELSR3 MEGF8

2.26e-0730855PS01248
DomainLaminin_G

HSPG2 CELSR1 THBS4 CELSR3 FAT3

6.57e-0658855IPR001791
DomainConA-like_dom

HSPG2 CELSR1 THBS4 ZAN CELSR3 TRIM58 FAT3 TRIM22

6.97e-06219858IPR013320
DomainEGF_extracell

SCARF1 JAG2 DNER MEGF11 NOTCH3

7.78e-0660855IPR013111
DomainEGF_2

SCARF1 JAG2 DNER MEGF11 NOTCH3

7.78e-0660855PF07974
DomainGAIN_dom_N

CELSR1 CELSR3 ADGRB1

1.46e-0511853IPR032471
DomainGAIN

CELSR1 CELSR3 ADGRB1

1.46e-0511853PF16489
DomainDUF4685

C9orf50 KIAA1614

2.05e-052852IPR032756
DomainDUF4685

C9orf50 KIAA1614

2.05e-052852PF15737
DomainLAM_G_DOMAIN

HSPG2 CELSR1 CELSR3 FAT3

2.62e-0538854PS50025
DomainLaminin_G_2

HSPG2 CELSR1 CELSR3 FAT3

3.22e-0540854PF02210
DomainLamG

HSPG2 CELSR1 CELSR3 FAT3

4.72e-0544854SM00282
Domain-

HSPG2 CELSR1 THBS4 CELSR3 FAT3

7.28e-05958552.60.120.200
DomainVWC_out

JAG2 ZAN SSPOP

8.36e-0519853SM00215
DomainNotch

NOTCH3 NOTCH4

1.22e-044852IPR008297
DomainNODP

NOTCH3 NOTCH4

1.22e-044852PF07684
DomainNotch_NODP_dom

NOTCH3 NOTCH4

1.22e-044852IPR011656
DomainDSL

JAG2 DLL1

1.22e-044852PF01414
DomainNotch_NOD_dom

NOTCH3 NOTCH4

1.22e-044852IPR010660
DomainNOD

NOTCH3 NOTCH4

1.22e-044852PF06816
DomainDSL

JAG2 DLL1

1.22e-044852SM00051
DomainNOD

NOTCH3 NOTCH4

1.22e-044852SM01338
DomainNODP

NOTCH3 NOTCH4

1.22e-044852SM01339
DomainHormR

CELSR1 CELSR3 ADGRB1

1.95e-0425853SM00008
DomainDSL

JAG2 DLL1

2.03e-045852IPR001774
DomainDSL

JAG2 DLL1

2.03e-045852PS51051
DomainNotch_ligand_N

JAG2 DLL1

2.03e-045852IPR011651
DomainLNR

NOTCH3 NOTCH4

2.03e-045852PS50258
DomainMNNL

JAG2 DLL1

2.03e-045852PF07657
DomainHRM

CELSR1 CELSR3 ADGRB1

2.74e-0428853PF02793
DomainTB

LTBP3 LTBP4

4.24e-047852PF00683
DomainNotch_dom

NOTCH3 NOTCH4

4.24e-047852IPR000800
DomainNotch

NOTCH3 NOTCH4

4.24e-047852PF00066
DomainNL

NOTCH3 NOTCH4

4.24e-047852SM00004
DomainGPS

CELSR1 CELSR3 ADGRB1

4.92e-0434853SM00303
DomainGPS

CELSR1 CELSR3 ADGRB1

5.36e-0435853PF01825
Domain-

LTBP3 LTBP4

5.63e-0488523.90.290.10
DomainVWFC_1

JAG2 ZAN SSPOP

5.83e-0436853PS01208
DomainGPS

CELSR1 CELSR3 ADGRB1

5.83e-0436853PS50221
DomainGPS

CELSR1 CELSR3 ADGRB1

6.32e-0437853IPR000203
DomainVWC

JAG2 ZAN SSPOP

6.84e-0438853SM00214
DomainVWFC_2

JAG2 ZAN SSPOP

6.84e-0438853PS50184
DomainTB

LTBP3 LTBP4

7.22e-049852PS51364
DomainTB_dom

LTBP3 LTBP4

7.22e-049852IPR017878
DomainG_PROTEIN_RECEP_F2_1

CELSR1 CELSR3 ADGRB1

7.96e-0440853PS00649
DomainGPCR_2_extracellular_dom

CELSR1 CELSR3 ADGRB1

7.96e-0440853IPR001879
DomainG_PROTEIN_RECEP_F2_3

CELSR1 CELSR3 ADGRB1

7.96e-0440853PS50227
DomainVWF_dom

JAG2 ZAN SSPOP

9.19e-0442853IPR001007
DomainFol_N

SNED1 DNER

1.10e-0311852IPR003645
DomainFOLN

SNED1 DNER

1.10e-0311852SM00274
DomainTIL

ZAN SSPOP

1.31e-0312852PF01826
DomainC8

ZAN SSPOP

1.31e-0312852PF08742
DomainG_PROTEIN_RECEP_F2_2

CELSR1 CELSR3 ADGRB1

1.53e-0350853PS00650
Domain7tm_2

CELSR1 CELSR3 ADGRB1

1.53e-0350853PF00002
DomainUnchr_dom_Cys-rich

ZAN SSPOP

1.55e-0313852IPR014853
DomainC8

ZAN SSPOP

1.55e-0313852SM00832
DomainTIL_dom

ZAN SSPOP

1.80e-0314852IPR002919
DomainVWD

ZAN SSPOP

2.36e-0316852SM00216
DomainVWF_type-D

ZAN SSPOP

2.36e-0316852IPR001846
DomainVWFD

ZAN SSPOP

2.36e-0316852PS51233
DomainVWD

ZAN SSPOP

2.36e-0316852PF00094
DomainGPCR_2_secretin-like

CELSR1 CELSR3 ADGRB1

2.58e-0360853IPR000832
DomainGPCR_2-like

CELSR1 CELSR3 ADGRB1

2.58e-0360853IPR017981
DomainEMI

SSPOP MEGF11

2.66e-0317852PS51041
DomainG_PROTEIN_RECEP_F2_4

CELSR1 CELSR3 ADGRB1

2.71e-0361853PS50261
DomainTSP_1

ADGRB1 CFP SSPOP

2.97e-0363853PF00090
DomainTSP1

ADGRB1 CFP SSPOP

3.24e-0365853SM00209
DomainTSP1_rpt

ADGRB1 CFP SSPOP

3.24e-0365853IPR000884
DomainTSP1

ADGRB1 CFP SSPOP

3.24e-0365853PS50092
Domain-

FBXO27 SSPOP EPHA8

4.50e-03738532.60.120.260
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 DNER DLL1 NOTCH3 NOTCH4

1.05e-0727625M39545
PathwayPID_NOTCH_PATHWAY

JAG2 DNER DLL1 SSPOP NOTCH3 NOTCH4

2.12e-0759626M17
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 NOTCH3 NOTCH4

2.35e-0713624M47423
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 DLL1 NOTCH3 NOTCH4

2.49e-0539624MM14604
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 NOTCH4

4.36e-0516623M47424
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 DLL1 NOTCH3 NOTCH4

4.42e-0545624M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 NOTCH3 NOTCH4

4.82e-0546624MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 NOTCH3 NOTCH4

5.25e-0547624M7946
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 DLL1 NOTCH3

7.47e-0519623MM15594
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 DLL1 NOTCH3 NOTCH4

1.47e-0461624M39540
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 DLL1 NOTCH3

1.74e-0425623M27879
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH3 NOTCH4

1.89e-045622M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH3 NOTCH4

1.89e-045622MM14733
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

CFP SSPOP NOTCH3 NOTCH4

2.24e-0468624M27303
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH3 NOTCH4

2.82e-046622M27068
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 DNER DLL1

3.34e-0431623M592
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 DLL1

3.94e-047622M27199
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH3 NOTCH4

3.94e-047622MM14734
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

HSPG2 CFP SSPOP NOTCH3 NOTCH4

4.07e-04143625M27275
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 DLL1 NOTCH3 NOTCH4

4.59e-0482624MM15922
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP3 LTBP4

5.24e-048622M47850
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

JAG2 DLL1

6.72e-049622M47866
PathwayREACTOME_DISEASES_OF_METABOLISM

HSPG2 EPM2A CFP SSPOP NOTCH3 NOTCH4

7.85e-04250626M27554
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH3 NOTCH4

1.02e-0311622M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH3 NOTCH4

1.22e-0312622M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH3 NOTCH4

1.22e-0312622M47533
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 DLL1 NOTCH3

1.29e-0349623M618
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH3 NOTCH4

1.44e-0313622M47534
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG2 DLL1 NOTCH3 NOTCH4

1.79e-03118624M39852
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 DLL1

1.93e-0315622M27202
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 DLL1

2.48e-0317622M39389
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

JAG2 MST1R HSPG2 CELSR1 C2CD3 KMT2D CELSR3 EPOP MEGF8 ATP13A1 ZNF408 ZNF516 ZNF316 WDR90 LTBP3 DLL1 LTBP4 ABCA7 SCARA3 D2HGDH CEP170B

3.82e-131105882135748872
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

JAG2 DLL1 NOTCH3 NOTCH4

1.91e-10588421602525
Pubmed

Human ligands of the Notch receptor.

JAG2 DLL1 NOTCH3 NOTCH4

1.33e-09788410079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 DLL1 NOTCH3 NOTCH4

1.33e-09788412846471
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 DLL1 NOTCH3 NOTCH4

2.66e-0988849858718
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 DLL1 NOTCH3 NOTCH4

4.77e-09988411118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 DLL1 NOTCH3 NOTCH4

4.77e-09988416245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 DLL1 NOTCH3 NOTCH4

7.94e-091088423665443
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 DLL1 NOTCH3 NOTCH4

1.25e-081188410878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 DLL1 NOTCH3 NOTCH4

1.25e-081188412866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 DLL1 NOTCH3 NOTCH4

1.86e-081288415465494
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 DLL1 NOTCH3 NOTCH4

2.69e-081388411578869
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 DLL1 NOTCH3 NOTCH4

3.76e-081488414757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 DLL1 NOTCH3 NOTCH4

5.11e-081588412971992
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 DLL1 NOTCH3 NOTCH4

6.80e-081688412617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 DLL1 NOTCH3 NOTCH4

6.80e-081688410842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 DLL1 NOTCH3 NOTCH4

6.80e-081688417273555
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 DLL1 NOTCH3 NOTCH4

8.88e-081788418694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 DLL1 NOTCH3 NOTCH4

8.88e-081788415821257
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 DLL1 NOTCH3 NOTCH4

1.14e-071888418093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 DLL1 NOTCH3 NOTCH4

1.14e-071888415689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 DLL1 NOTCH3 NOTCH4

1.44e-071988416518823
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

DLL1 NOTCH3 NOTCH4

1.56e-07588321726900
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

JAG2 DLL1 NOTCH3

1.56e-07588311006133
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

DLL1 NOTCH3 NOTCH4

1.56e-07588320554499
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 DLL1 NOTCH3 NOTCH4

2.22e-072188428656980
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

JAG2 MST1R HSPG2 CELSR1 IGFBP4 CELSR3 MEGF8 DNER SMPD1 LTBP3 R3HDM1 TAP1 ABCA7 SCARA3 NOTCH3

3.25e-071201881535696571
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG2 DLL1 NOTCH3 NOTCH4

3.27e-072388414701881
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

JAG2 DLL1 NOTCH3 NOTCH4

5.48e-072688419369401
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

JAG2 DLL1 NOTCH3 NOTCH4

8.66e-072988425535917
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 DLL1 NOTCH3

8.69e-07888311044610
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

JAG2 DLL1 NOTCH3 NOTCH4

9.97e-073088424552588
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

JAG2 DLL1 NOTCH4

1.30e-06988310837027
Pubmed

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

JAG2 DLL1 NOTCH3 NOTCH4

1.67e-063488421311046
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

JAG2 DLL1 NOTCH3 NOTCH4

1.89e-063588421252157
Pubmed

Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.

JAG2 DLL1 NOTCH3 NOTCH4

2.37e-063788424673559
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH3 NOTCH4

2.55e-061188316607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

DLL1 NOTCH3 NOTCH4

2.55e-061188315499562
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

DLL1 NOTCH3 NOTCH4

2.55e-06118839187150
Pubmed

Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.

JAG2 THBS4 DLL1 NOTCH3 NOTCH4

2.74e-068688535103284
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

DLL1 NOTCH3 NOTCH4

3.39e-061288310952889
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG2 DLL1 NOTCH3 NOTCH4

3.61e-064188422675208
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 DLL1 NOTCH3

4.40e-061388331202705
Pubmed

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells.

FUT4 DLL1 NOTCH3

4.40e-061388323132245
Pubmed

The notch pathway positively regulates programmed cell death during erythroid differentiation.

JAG2 DLL1 NOTCH3 NOTCH4

4.81e-064488417476283
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

JAG2 NOTCH3 NOTCH4

5.58e-061488328192800
Pubmed

BDNF-TrkB signaling orchestrates the buildup process of local sleep.

SLC32A1 RASGRF2

6.33e-06288239046880
Pubmed

Control of lung development by latent TGF-β binding proteins.

LTBP3 LTBP4

6.33e-06288220945348
Pubmed

Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.

NOTCH3 NOTCH4

6.33e-06288233665264
Pubmed

Engagement of activated Notch signalling in collagen II-specific T helper type 1 (Th1)- and Th17-type expansion involving Notch3 and Delta-like1.

DLL1 NOTCH3

6.33e-06288221235539
Pubmed

Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.

NOTCH3 NOTCH4

6.33e-06288217696940
Pubmed

Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy.

SLC32A1 HCRT

6.33e-06288231411561
Pubmed

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.

NOTCH3 NOTCH4

6.33e-06288225658374
Pubmed

Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress.

THBS4 KMT2D

6.33e-06288238876442
Pubmed

Regulation of Lateral Hypothalamic Orexin Activity by Local GABAergic Neurons.

SLC32A1 HCRT

6.33e-06288229311142
Pubmed

A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.

NOTCH3 NOTCH4

6.33e-06288211777956
Pubmed

Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity.

JAG2 DLL1

6.33e-06288230940183
Pubmed

GABAergic Neurons of the Central Amygdala Promote Cataplexy.

SLC32A1 HCRT

6.33e-06288228235898
Pubmed

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.

JAG2 DLL1 NOTCH3 NOTCH4

6.84e-064888435247391
Pubmed

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

JAG2 DLL1 NOTCH3

6.97e-061588317194759
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

JAG2 DLL1 NOTCH3

6.97e-06158839291577
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR1 CELSR3 SSPOP

6.97e-061588320473291
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 DLL1 NOTCH3

6.97e-061588312167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 DLL1 NOTCH3

6.97e-061588316914494
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

DLL1 NOTCH3 NOTCH4

8.56e-061688311739954
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 DLL1 NOTCH3

8.56e-061688332161758
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

DLL1 NOTCH3 NOTCH4

1.04e-051788339315665
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

JAG2 HSPG2 MEGF8 LTBP3 LTBP4

1.29e-0511888521078624
Pubmed

Monoclonal antibodies that recognize lacto-N-fucopentaose III (CD15) react with the adhesion-promoting glycoprotein family (LFA-1/HMac-1/gp 150,95) and CR1 on human neutrophils.

FUT4 CR1

1.90e-0538823305706
Pubmed

Heat shock protein 90 mediates efficient antigen cross presentation through the scavenger receptor expressed by endothelial cells-I.

SCARF1 TAP1

1.90e-05388220686127
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH3 NOTCH4

1.90e-05388225846406
Pubmed

A distinct parabrachial-to-lateral hypothalamus circuit for motivational suppression of feeding by nociception.

SLC32A1 HCRT

1.90e-05388233962958
Pubmed

Amygdala lesions reduce cataplexy in orexin knock-out mice.

SLC32A1 HCRT

1.90e-05388223739970
Pubmed

Structure and Function of Neuronal Circuits Linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area.

SLC32A1 HCRT

1.90e-05388237117013
Pubmed

Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development.

DLL1 NOTCH3

1.90e-0538828923452
Pubmed

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

DLL1 NOTCH3

1.90e-05388212482954
Pubmed

Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells.

JAG2 DLL1

1.90e-0538829716576
Pubmed

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

JAG2 DLL1

1.90e-05388221372153
Pubmed

The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.

CELSR1 CELSR3

1.90e-05388211677057
Pubmed

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.

DLL1 NOTCH4

1.90e-05388211823422
Pubmed

CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease.

CR1 ABCA7

1.90e-05388224530172
Pubmed

Brain Circuit of Claustrophobia-like Behavior in Mice Identified by Upstream Tracing of Sighing.

SLC32A1 HCRT

1.90e-05388232553161
Pubmed

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype.

NOTCH3 NOTCH4

1.90e-05388215645445
Pubmed

The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage.

JAG2 DLL1

1.90e-05388212551931
Pubmed

Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.

JAG2 FUT4 DLL1

2.01e-052188331631837
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG2 NOTCH3 NOTCH4

2.01e-052188314702043
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG2 DLL1 NOTCH3

2.33e-052288321750033
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

JAG2 HSPG2 TOX4 MEGF8 R3HDM1 LTBP4 SSPOP TRIM22 MEGF11

2.41e-0560888916713569
Pubmed

Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.

JAG2 DLL1 NOTCH3

2.67e-052388324337118
Pubmed

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.

DLL1 NOTCH3 NOTCH4

2.67e-052388336239412
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

JAG2 NOTCH3 NOTCH4

3.05e-052488321420948
Pubmed

MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma.

FUT4 DLL1

3.79e-05488221931765
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH3 NOTCH4

3.79e-05488228061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH3 NOTCH4

3.79e-05488224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH3 NOTCH4

3.79e-05488220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH3 NOTCH4

3.79e-05488219404845
Pubmed

Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.

JAG2 DLL1

3.79e-05488220602435
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH3 NOTCH4

3.79e-05488228669409
Pubmed

Notch signalling pathway mediates hair cell development in mammalian cochlea.

JAG2 DLL1

3.79e-05488210080181
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP3 LTBP4

3.79e-05488215611103
InteractionPRG2 interactions

JAG2 MST1R HSPG2 CELSR1 TNFRSF6B LTBP3 LTBP4 SCARA3 ZMYM3 NOTCH3

4.67e-072858810int:PRG2
InteractionTOP3B interactions

JAG2 MST1R HSPG2 CELSR1 C2CD3 KMT2D CELSR3 EPOP MEGF8 ATP13A1 ZNF408 ZNF516 ZNF316 WDR90 LTBP3 DLL1 LTBP4 ABCA7 SCARA3 D2HGDH CEP170B

1.00e-0614708821int:TOP3B
InteractionMFAP5 interactions

JAG2 DLL1 LTBP4 CTU1 NOTCH3

3.13e-0652885int:MFAP5
InteractionEDN3 interactions

JAG2 HSPG2 CELSR1 MEGF8 TNFRSF6B DDX11

7.81e-06108886int:EDN3
InteractionVWCE interactions

ZNF358 ZNF408 ZNF316 LTBP4 CTU1

8.81e-0664885int:VWCE
InteractionOIT3 interactions

JAG2 CELSR1 TNFRSF6B FBXO27 LTBP4

9.51e-0665885int:OIT3
InteractionNOTCH2 interactions

ZNF787 JAG2 IGFBP4 ZNF358 ZNF408 ZNF316 DLL1 LTBP4 NOTCH3 NOTCH4

1.57e-054238810int:NOTCH2
InteractionHOXA1 interactions

JAG2 MEGF8 KRT33B ZNF837 CFP LTBP3 R3HDM1 LTBP4 NOTCH3

2.53e-05356889int:HOXA1
InteractionLDLRAD1 interactions

ATP13A1 ZNF316 TNFRSF6B LTBP4 TAP1 CTU1 LRRC41

2.66e-05199887int:LDLRAD1
InteractionDCANP1 interactions

CELSR1 CELSR3 FAT3

7.41e-0519883int:DCANP1
InteractionFBXO2 interactions

JAG2 SNED1 HSPG2 CELSR3 MEGF8 LTBP4 SCARA3 CTU1 NOTCH3

7.71e-05411889int:FBXO2
InteractionFHL5 interactions

ZNF408 CFP ZNHIT1 CTU1 LRRC41

8.45e-05102885int:FHL5
InteractionNOTCH3 interactions

JAG2 ZNF408 DLL1 NOTCH3 NOTCH4

1.37e-04113885int:NOTCH3
InteractionNTN5 interactions

JAG2 LTBP4 NOTCH3

1.52e-0424883int:NTN5
InteractionATN1 interactions

JAG2 HSPG2 MEGF8 LTBP4 SSPOP MEGF11

1.70e-04187886int:ATN1
InteractionFBLN2 interactions

HSPG2 ZNF358 ZNF408 ZNF316

1.99e-0466884int:FBLN2
InteractionCACNA1A interactions

JAG2 HSPG2 MEGF8 LTBP3 LTBP4

2.04e-04123885int:CACNA1A
InteractionBRICD5 interactions

JAG2 MST1R HSPG2 CELSR1 TAP1 SCARA3

2.07e-04194886int:BRICD5
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR3

3.35e-053612913
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR3

3.35e-0536121189
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP3 LTBP4

6.69e-054612628
GeneFamilyINO80 complex |SRCAP complex

VPS72 ZNHIT1

3.97e-0496121329
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF1 SCARA3

3.72e-03276121253
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 DLL1 NOTCH3 NOTCH4

2.09e-0716884MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 DLL1 NOTCH3 NOTCH4

2.09e-0716884M2207
CoexpressionNABA_CORE_MATRISOME

SNED1 HSPG2 LAMB4 THBS4 IGFBP4 LTBP3 LTBP4 SSPOP

4.13e-06275888M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 LAMB4 THBS4 IGFBP4 LTBP3 LTBP4 SSPOP

4.47e-06196887M3008
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

JAG2 SLC32A1 DMGDH CELSR1 THBS4 ADGRB1 GRIN2C VSX1 OPRD1 EPHA8

2.93e-055918810M2019
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

JAG2 SLC32A1 DMGDH CELSR1 THBS4 ADGRB1 GRIN2C VSX1 OPRD1 EPHA8

3.38e-056018810MM866
CoexpressionNABA_CORE_MATRISOME

SNED1 HSPG2 THBS4 IGFBP4 LTBP3 LTBP4 SSPOP

3.55e-05270887MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

SNED1 THBS4 IGFBP4 LTBP3 LTBP4 SSPOP

4.57e-05191886MM17059
CoexpressionGSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_UP

HSPG2 LTBP3 FUT4 NT5DC3 HCRT OPRD1

5.74e-05199886M3641
CoexpressionGSE2826_XID_VS_BTK_KO_BCELL_DN

IGFBP4 DBNDD2 CFP TAP1 NOTCH4 INVS

5.90e-05200886M4901
CoexpressionDESCARTES_FETAL_PANCREAS_VASCULAR_ENDOTHELIAL_CELLS

JAG2 HSPG2 AVPR2 NOTCH4

6.87e-0565884M40266
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

DMGDH TMEM30B THBS4 RASGRF2 TRIM58 C9orf50 GRIN2C FUT4 SCARA3

8.92e-05544889M1936
CoexpressionGSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_UP

FBXL22 ZAN GRIN2C SCARA3 CTU1

9.36e-05135885M2916
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_BREAST_CANCER_TUMOR_CELL_DERIVED

SNED1 IGFBP4 LTBP3

1.25e-0429883M47987
CoexpressionMEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED

DMGDH TMEM30B THBS4 RASGRF2 TRIM58 C9orf50 GRIN2C FUT4 SCARA3

1.34e-04574889MM820
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 RASGRF2 AVPR2 NOTCH4

1.56e-06180886755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 RASGRF2 HCRT NOTCH4

1.56e-061808865861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SCARF1 HSPG2 LAMB4 IGFBP4 AVPR2 NOTCH4

1.66e-06182886d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 RASGRF2 TAP1 NOTCH4

1.94e-0618788629b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SCARF1 HSPG2 LAMB4 IGFBP4 AVPR2 NOTCH4

1.94e-06187886be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 HSPG2 IGFBP4 RASGRF2 TNFRSF6B NOTCH4

2.00e-06188886a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 RASGRF2 HCRT NOTCH4

2.13e-061908861307688255a1250fa300edf2c41f1affe31dcc98
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 HSPG2 IGFBP4 LTBP3 LTBP4 SCARA3

2.13e-061908863cf464664d6aa22b212e60b70885953887e92483
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IGFBP4 DNER LTBP3 LTBP4 SCARA3

2.33e-06193886858a186804b36d45957238d3d3eed2768b961641
ToppCellIPF-Endothelial-VE_Arterial|IPF / Disease state, Lineage and Cell class

JAG2 HSPG2 IGFBP4 RASGRF2 LTBP4 NOTCH4

2.33e-06193886bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IGFBP4 DNER LTBP3 LTBP4 SCARA3

2.33e-061938867865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCellIPF-Endothelial-VE_Arterial|World / Disease state, Lineage and Cell class

JAG2 HSPG2 IGFBP4 RASGRF2 LTBP4 NOTCH4

2.33e-0619388670a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 CFP DLL1

2.40e-06194886efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 IGFBP4 AVPR2 CFP NOTCH4

2.63e-0619788621a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCell18-Distal-Endothelial-Endothelial|Distal / Age, Tissue, Lineage and Cell class

SCARF1 JAG2 HSPG2 IGFBP4 CFP NOTCH4

2.70e-06198886efd3af3c0b4ab29605331ecdcb7a52cba38e6028
ToppCell18-Distal-Endothelial|Distal / Age, Tissue, Lineage and Cell class

SCARF1 JAG2 HSPG2 IGFBP4 CFP NOTCH4

2.70e-06198886ee657a84928d54eb7a9a66c7acb19a7c119d6423
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SNED1 HSPG2 THBS4 IGFBP4 LTBP3 SCARA3

2.78e-0619988640de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT3 SMPD1 KCNK12 FBXO27 CR1 KIAA1614

2.78e-061998864e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZNF787 EPM2A FUT4 FBXO27 NOTCH3

1.13e-05148885e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZNF787 EPM2A FUT4 FBXO27 NOTCH3

1.13e-05148885c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

HSPG2 IGFBP4 RASGRF2 AVPR2 NOTCH4

1.51e-05157885275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPOP RASGRF2 TTC39A WDR90 OPRD1

1.91e-05165885c39f0479955c4e23921f7a450d3bc251a002200f
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 IGFBP4 RASGRF2 FRMPD3 NOTCH4

2.15e-051698850d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JAG2 HSPG2 IGFBP4 HCRT NOTCH4

2.40e-051738853a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAG2 HSPG2 RASGRF2 AVPR2 NOTCH4

2.47e-0517488518ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

JAG2 HSPG2 IGFBP4 LTBP3 LTBP4

2.61e-0517688552af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCARF1 HSPG2 IGFBP4 RASGRF2 NOTCH4

2.68e-05177885fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCARF1 HSPG2 IGFBP4 RASGRF2 NOTCH4

2.68e-0517788512f8627124acbf436e75681ff1ce429ff5e3f256
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM30B FUT4 ABCA7 NR0B2 OPRD1

2.68e-0517788543dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAG2 HSPG2 LAMB4 IGFBP4 NOTCH4

2.98e-051818857d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SNED1 CELSR1 IGFBP4 LTBP4

3.06e-051828852cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 DNER ADARB2-AS1 FRMPD3 MEGF11

3.06e-051828857dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SNED1 CELSR1 IGFBP4 LTBP4

3.06e-051828850cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 ZAN IGFBP4

3.06e-05182885d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SNED1 CELSR1 IGFBP4 LTBP4

3.06e-051828853e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellBasal|World / shred by cell class for mouse tongue

JAG2 CELSR1 IGFBP4 DLL1 LTBP4

3.14e-05183885c6729a207526ff4aa48176207b9353176f631fea
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 DNER ADARB2-AS1 FRMPD3 MEGF11

3.14e-05183885e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SCARF1 HSPG2 IGFBP4 AVPR2 NOTCH4

3.14e-051838853e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 IGFBP4 RASGRF2 LTBP4 NOTCH4

3.22e-05184885087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 DNER ADARB2-AS1 FRMPD3 MEGF11

3.31e-05185885027020754dbf71b0034791f9a34ae795e3b85f81
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 DNER ADARB2-AS1 FRMPD3 MEGF11

3.31e-0518588508fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCARF1 HSPG2 IGFBP4 HCRT NOTCH4

3.40e-05186885a906020a8df6fcca474b278f746c553b177a56b4
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 IGFBP4 RASGRF2 LTBP4 NOTCH4

3.40e-051868855d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 ADGRB1 DNER ADARB2-AS1 MEGF11

3.40e-05186885310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JAG2 HSPG2 IGFBP4 AVPR2 NOTCH4

3.40e-05186885a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 DNER ADARB2-AS1 FRMPD3 MEGF11

3.48e-05187885ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 CFP DLL1

3.48e-0518788503de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 RASGRF2 LTBP4 NOTCH3 NOTCH4

3.57e-05188885ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 HSPG2 IGFBP4 AVPR2 NOTCH4

3.57e-051888850026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

SCARF1 THBS4 LTBP3 DLL1 NOTCH4

3.57e-05188885c90669b51e1902fe7726555290c91c92a911df83
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

SCARF1 HSPG2 IGFBP4 RASGRF2 NOTCH4

3.66e-05189885c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IGFBP4 DNER LTBP4 SCARA3

3.66e-05189885f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAG2 HSPG2 RASGRF2 LTBP4 NOTCH4

3.66e-0518988512b6f1c3bf526b90e112374bf937701f645c5780
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 IGFBP4 DNER LTBP4 SCARA3

3.66e-05189885378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAG2 HSPG2 RASGRF2 TNFRSF6B NOTCH4

3.76e-0519088506bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JAG2 HSPG2 RASGRF2 LTBP4 NOTCH4

3.76e-05190885aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 RASGRF2 MEGF11 NOTCH4

3.76e-0519088538a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

3.76e-05190885141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 RASGRF2 MEGF11 NOTCH4

3.76e-05190885bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCARF1 JAG2 RASGRF2 MEGF11 NOTCH4

3.76e-05190885d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JAG2 HSPG2 IGFBP4 RASGRF2 NOTCH4

3.85e-05191885cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC32A1 DNER ADARB2-AS1 FRMPD3 MEGF11

3.85e-051918857b386512284dfaa0e95358b28ee82632ee965e64
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAG2 HSPG2 RASGRF2 AVPR2 NOTCH4

3.85e-0519188504c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAG2 HSPG2 RASGRF2 AVPR2 NOTCH4

3.85e-05191885db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 AVPR2 CFP NOTCH4

3.95e-051928857dbe3117a0f58ff2e838963d49f788a59a4351d7
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 DNER LTBP3 LTBP4 SCARA3

3.95e-05192885a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 IGFBP4 DNER LTBP4 SCARA3

3.95e-051928850e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 DNER LTBP3 LTBP4 SCARA3

3.95e-05192885eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SNED1 IGFBP4 FAT3 LTBP4 SCARA3

3.95e-05192885162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 TAP1 NOTCH4

4.05e-05193885d338a7c0585b69947c37f44aa0381619493e31ea
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JAG2 SNED1 HSPG2 RASGRF2 NOTCH4

4.05e-051938852e72309607902dabe3218888b22a77fe941f3570
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM30B THBS4 TTC39A FUT4 DLL1

4.05e-051938855a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 IGFBP4 DNER LTBP4 SCARA3

4.05e-05193885025836c5c5a711e477c326559e618e47cae42d11
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM30B THBS4 TTC39A FUT4 DLL1

4.05e-0519388564bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCell15-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

SCARF1 JAG2 HSPG2 AVPR2 NOTCH4

4.15e-05194885ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell15-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

SCARF1 JAG2 HSPG2 AVPR2 NOTCH4

4.15e-05194885f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCellPCW_05-06-Endothelial-Endothelial_mature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 CFP NOTCH4

4.25e-0519588554fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 DLL1

4.25e-05195885cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 HSPG2 IGFBP4 AVPR2 NOTCH4

4.25e-05195885f65053811074a7f2ff0368f3a63b88e2a08da1a0
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.25e-05195885a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.25e-05195885dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCellPCW_13-14-Endothelial-Endothelial_mature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.25e-0519588531353269591c9eee84872838e91995d4a035da46
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.36e-051968859b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCellPCW_13-14-Endothelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.36e-051968857286de29a34e13834cd6347c67a1443897fa4ade
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCARF1 HSPG2 IGFBP4 AVPR2 NOTCH4

4.36e-05196885d5d3028fcbfa251a206d17ec33b3b313968f9d79
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.36e-05196885ccf6881c09e570116cf1bcb71112765ea8c28418
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAG2 IGFBP4 RASGRF2 LTBP4 NOTCH4

4.36e-05196885cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCellPCW_10-12-Endothelial-Endothelial_immature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.36e-05196885c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCellPCW_10-12-Endothelial-Endothelial_mature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.36e-05196885481d79bdaec069ad2746a28d39eeee8d3edf7305
ToppCell11.5-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

SCARF1 JAG2 HSPG2 CFP NOTCH4

4.36e-05196885509ddea8d6e1d0b832f69490ab8a736af4ca19a8
ToppCellPCW_10-12-Endothelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.36e-051968852c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JAG2 HSPG2 RASGRF2 TNFRSF6B NOTCH4

4.36e-05196885ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCell11.5-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

SCARF1 JAG2 HSPG2 CFP NOTCH4

4.36e-05196885e7d55933e23599122e20498548abf5b30fc25c8f
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SNED1 HSPG2 IGFBP4 TNFRSF6B NOTCH4

4.46e-0519788562c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.46e-05197885a312d9cf4ced949307eb9620be4eed926300b892
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 HSPG2 IGFBP4 AVPR2 NOTCH4

4.46e-05197885131bc6ef55f467cc802db68daf7e7d757ea64fc6
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.46e-051978854623cce5eca0c26c8103950e9874b40918226aa5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.46e-05197885f4834378d5d31560b4efe5dee0d5b5d11caeb10f
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.46e-05197885dfc052a447c3b32235fcaffdf06c4e0941723d19
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 HSPG2 IGFBP4 NOTCH4

4.46e-051978859b3d6fe76dd7d61a286a28d9466b5f2fece048e1
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A

JAG2 DCAF15 ACBD4 SMPD1 FUT4 ABCA7 ZMYM3

9.94e-061958775571_DN
DrugFursultiamine Hydrochloride [2105-43-3]; Up 200; 9.2uM; HL60; HT_HG-U133A

SCARF1 HSPG2 KATNB1 TNFRSF6B KCNK12 ABCA7 LRRC41

1.10e-051988772929_UP
DrugPiretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A

JAG2 THBS4 CELSR3 ZNF408 KATNB1 TNFRSF6B CEP170B

1.10e-051988776144_DN
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH3 NOTCH4

4.63e-0524863C0887833
DiseaseMalignant neoplasm of breast

JAG2 KMT2D VPS72 RASGRF2 AVPR2 CFP KEAP1 DLL1 CTU1 NOTCH3 NOTCH4

2.85e-0410748611C0006142
Diseasemyeloid white cell count

IPPK JAG2 VPS72 TRIM58 ATP13A1 ZNF516 ZNF316 SSH2 ABCA7 KIAA1614

3.97e-049378610EFO_0007988
Diseaseneutrophil count

IPPK JAG2 MST1R VPS72 TRIM58 ATP13A1 ZNF516 ZNF316 SSH2 R3HDM1 ABCA7 NOTCH4

6.57e-0413828612EFO_0004833
DiseaseImpaired cognition

CR1 NOTCH3

7.47e-0414862C0338656
Diseaseidiopathic scoliosis (implicated_via_orthology)

KATNB1 SSPOP

9.81e-0416862DOID:0060250 (implicated_via_orthology)
DiseaseCraniofacial Abnormalities

JAG2 HSPG2 LTBP3 VSX1

1.14e-03156864C0376634
DiseaseGlioblastoma

JAG2 LTBP4 NOTCH3

1.61e-0379863C0017636
Diseasedilated cardiomyopathy (implicated_via_orthology)

JAG2 DNER DLL1

1.67e-0380863DOID:12930 (implicated_via_orthology)
DiseaseGiant Cell Glioblastoma

JAG2 LTBP4 NOTCH3

1.92e-0384863C0334588
DiseaseSquamous cell carcinoma of esophagus

KMT2D FAT3 NOTCH3

2.73e-0395863C0279626

Protein segments in the cluster

PeptideGeneStartEntry
GACLARRRPPGSPCS

nan

56

A8MZ25
FCPRPCALPGRPGLT

EPM2A

191

B3EWF7
NPSGEGSRPCRQRCP

C9orf50

256

Q5SZB4
APCPPQRKRGCGAAR

ACBD4

206

Q8NC06
FQGPNCPATCGRVLP

AAMP

211

Q13685
DRTRTCRPPQFGGNP

ADGRB1

431

O14514
PLCCRRGSGLPPASR

SMPD1

226

P17405
VPCGARPCGVRPDGQ

ATP13A1

11

Q9HD20
CQQSCVGASRPPGRP

ADARB2-AS1

81

A8MUL3
IHPINGLRCRCPPGF

CELSR1

1341

Q9NYQ6
LRNFPQRASCGPPSL

CEP170B

1561

Q9Y4F5
PSPACQCSRPGARRL

ABCA7

1341

Q8IZY2
PQSQPRRHPLCCGSG

R3HDM1

1021

Q15032
RPLPCGPQEAACRNG

HSPG2

281

P98160
GTRCLCLPGFSGPRC

HSPG2

4161

P98160
GPQGPRVCEASPFSR

IPPK

286

Q9H8X2
CAPGFRGPLCQRICP

MEGF11

596

A6BM72
GARSGCGPRAQPCVP

GLTPD2

36

A6NH11
RPPPDCRLRFNISGC

FUT4

206

P22083
INGYRCSCPPGRAGP

JAG2

846

Q9Y219
CSCPPGRAGPRCQEV

JAG2

851

Q9Y219
APPAPGSERRCQACG

KIAA1614

526

Q5VZ46
PGPVRSVLFNPDGCC

KATNB1

231

Q9BVA0
CCPAPGAPLARRNAI

KCNK12

321

Q9HB15
QTPRGPRCACPPGLS

NOTCH3

1306

Q9UM47
SPLGPCRCEPGFLGR

MEGF8

186

Q7Z7M0
LAYEQRRCTGLPPCP

CFP

241

P27918
EGFCQRSAPGPAICP

DDX11

851

Q96FC9
PGACPCQGAASRPAI

NR0B2

6

Q15466
FRNGRRACLPAPCPD

OSBPL6

551

Q9BZF3
QLCRKPCGRPDPSSF

OPRD1

331

P41143
GGTCRPAPCVPRFAA

GIG44

81

P09565
QREGPSCPSPGPFCR

C2CD3

2106

Q4AC94
NCRRKSCGPPPEPFN

CR1

1451

P17927
GAPSPGPLCLLFRLC

DBNDD2

71

Q9BQY9
RGGAGPPPCACRTFF

DLL1

46

O00548
FPHFGVRSCAPPGRC

EPOP

126

A6NHQ4
LQPPAPGRCSCQLRS

FRMPD3

1301

Q5JV73
PPRPGACSRCGALAS

CTU1

281

Q7Z7A3
CPPPAFVRSCFDLRG

EPHA8

911

P29322
SRRPFLCQCPPGKLG

FAT3

3816

Q8TDW7
AAGQGRALPPPCSCA

TMEM30B

81

Q3MIR4
GAQCRPCPPRGAGSH

LTBP3

1171

Q9NS15
SCPLQGSPGRPRSVC

DMGDH

16

Q9UI17
RNPQVCGPGRCISRP

LTBP4

551

Q8N2S1
ACPAGFRSRGPGAPC

LTBP4

736

Q8N2S1
RPSGAGACCRFLPLQ

KEAP1

6

Q14145
PPGRCIPCDCNRAGT

LAMB4

1121

A4D0S4
PHSGQCPCRPGALGR

CELSR3

2091

Q9NYQ7
SPARNARPCPLGRFC

FBXO27

91

Q8NI29
PLSAPGPCAAQPCRN

DNER

41

Q8NFT8
QPCRNGGVCTSRPEP

DNER

51

Q8NFT8
PCTQKGRPGPRCSRC

SCARA3

31

Q6AZY7
EARPALCPGPSGSRC

DCAF15

341

Q66K64
RPVGPLARRGCCSAP

D2HGDH

26

Q8N465
GRRSPDSCRPQALPC

INVS

611

Q9Y283
AGAEPAPRPCLGRRC

HCRT

101

O43612
VPPSLCPCQLGARRY

SSPOP

876

A2VEC9
PPCPGPARQSRTCST

SSPOP

3676

A2VEC9
PPCRLCGEASRGRAP

LRRC41

261

Q15345
CSCERTPAPPRAGAG

RASGRF2

71

O14827
ARGRPCAGPARPLCT

NT5DC3

31

Q86UY8
PCGFARTRVCPPTFP

FBXL22

226

Q6P050
TCPFCRAPSQLPRGG

RNF227

76

A6NIN4
CPAPRGCRCLPGASL

TAP1

6

Q03518
TPRCGSGLRCYPPRG

IGFBP4

71

P22692
VRPRGLLCGSFPEPC

NOTCH4

21

Q99466
CELRAGPCPPRGCSN

NOTCH4

231

Q99466
PGFRGARCELPCPAG

SCARF1

241

Q14162
IAPSPCFRSPCVNGG

SNED1

656

Q8TER0
CPPCGDYSERSPRRG

ZNF837

341

Q96EG3
CGFGTQPPAAARAPC

VSX1

86

Q9NZR4
PPRRCDSNPCFRGVQ

THBS4

286

P35443
PAPGGQPRRCCFSEE

ZNF516

601

Q92618
SPPCCGRPEQQRLAA

WDR90

1486

Q96KV7
QCACPAPGLAVAPRQ

SSH2

1381

Q76I76
LGHRGVRPFPCPQCD

ZNF408

401

Q9H9D4
RLHSGERPFPCPQCG

ZNF408

571

Q9H9D4
RATPVCCAGQGPPRS

UNQ6494/PRO21346

76

Q6UXR6
PFPCPECGARFARGS

ZNF316

746

A6NFI3
PFPCPECGKRFSQRS

ZNF316

886

A6NFI3
NACCAPRFPTLGGRV

SLC32A1

191

Q9H598
AGPPSRPQRPFCAVC

ZNHIT1

106

O43257
RPQRPFCAVCGFPSP

ZNHIT1

111

O43257
GTGPVNPPARCSRTF

VPS72

251

Q15906
PCRGFCPSAGFPGRT

XKR5

606

Q6UX68
CPVCQTRFQPGNLRP

TRIM22

56

Q8IYM9
ACSCPPGPGRQHLFL

TTC39A

161

Q5SRH9
PIQGPGCRHFLTCGR

MST1R

521

Q04912
LSPQPRCVRSGCENP

TOX4

566

O94842
QAGLTGPPRPCSFCR

ZMYM3

536

Q14202
ACPQCRGPFRPSGFR

TRIM58

56

Q8NG06
CCARGRTPPSLGPQD

AVPR2

341

P30518
SPPRPFSCPDCGRAF

ZNF358

146

Q9NW07
QCPPGTFVQRPCRRD

TNFRSF6B

51

O95407
SPRPSCGPLCREGCV

ZAN

1061

Q9Y493
KPFVCPRCGRGFSQP

ZNF787

176

Q6DD87
TRLGASIPCRSPGCP

KMT2D

176

O14686
PIGSCVTNPCGPRSR

KRT33B

381

Q14525
VTNPCGPRSRCGPCN

KRT33B

386

Q14525
PGTGGCVPNTVPCRR

GRIN2C

421

Q14957