Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	substrate-independent telencephalic tangential migration	FEZF2 LHX6 SLIT3	2.54e-05	13	94	3	GO:0021826
GeneOntologyBiologicalProcess	substrate-independent telencephalic tangential interneuron migration	FEZF2 LHX6 SLIT3	2.54e-05	13	94	3	GO:0021843
GeneOntologyBiologicalProcess	neuron projection morphogenesis	ARHGEF28 FEZF2 LRRK2 SPG11 AMIGO1 SLITRK2 CYFIP1 KIDINS220 DST SLIT3 TSC22D4 NOTCH2 PLXNB3	6.93e-05	802	94	13	GO:0048812
GeneOntologyBiologicalProcess	semi-lunar valve development	TIE1 SLIT3 NOTCH2 SMAD2	7.93e-05	50	94	4	GO:1905314
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	ARHGEF28 FEZF2 LRRK2 SPG11 AMIGO1 SLITRK2 CYFIP1 KIDINS220 DST SLIT3 TSC22D4 NOTCH2 PLXNB3	8.56e-05	819	94	13	GO:0120039
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	HDAC4 LRRK2 NRG2 PPARG ATP13A2 CYRIB MAP3K1 AMIGO1 ZNF750 SLITRK2 PTPN13 CYFIP1 BRCA1 TIE1 NLGN2 PLXNB3	8.73e-05	1189	94	16	GO:0044087
GeneOntologyBiologicalProcess	cell morphogenesis	ARHGEF28 FEZF2 LRRK2 SPG11 MAP3K1 AMIGO1 HOXA13 SLITRK2 CYFIP1 KIDINS220 DST SLIT3 TSC22D4 DNMBP NOTCH2 PLXNB3	9.17e-05	1194	94	16	GO:0000902
GeneOntologyBiologicalProcess	cell projection morphogenesis	ARHGEF28 FEZF2 LRRK2 SPG11 AMIGO1 SLITRK2 CYFIP1 KIDINS220 DST SLIT3 TSC22D4 NOTCH2 PLXNB3	9.32e-05	826	94	13	GO:0048858
GeneOntologyBiologicalProcess	response to manganese ion	LRRK2 ATP13A2 PTGS2	1.15e-04	21	94	3	GO:0010042
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	ARHGEF28 FEZF2 LRRK2 SPG11 AMIGO1 SLITRK2 CYFIP1 KIDINS220 DST SLIT3 NOTCH2 PLXNB3	1.48e-04	748	94	12	GO:0048667
GeneOntologyBiologicalProcess	heart valve morphogenesis	TIE1 SLIT3 NOTCH2 SMAD2	1.96e-04	63	94	4	GO:0003179
Domain	LRR_8	MXRA5 LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3	3.73e-05	171	100	7	PF13855
Domain	LRR_TYP	MXRA5 LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3	4.65e-05	177	100	7	SM00369
Domain	Leu-rich_rpt_typical-subtyp	MXRA5 LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3	4.65e-05	177	100	7	IPR003591
Domain	ANK_REPEAT	PPP1R12B MUC16 MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	6.45e-05	253	100	8	PS50088
Domain	Ankyrin_rpt-contain_dom	PPP1R12B LRRK2 MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	6.64e-05	254	100	8	IPR020683
Domain	ANK_REP_REGION	PPP1R12B MUC16 MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	6.64e-05	254	100	8	PS50297
Domain	Ankyrin_rpt	PPP1R12B LRRK2 MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	8.24e-05	262	100	8	IPR002110
Domain	LRR	LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3 LRMDA	1.04e-04	201	100	7	PS51450
Domain	Leu-rich_rpt	MXRA5 LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3 LRMDA	1.04e-04	271	100	8	IPR001611
Domain	Cys-rich_flank_reg_C	MXRA5 AMIGO1 TRIL SLITRK2 SLIT3	1.22e-04	90	100	5	IPR000483
Domain	LRRCT	MXRA5 AMIGO1 TRIL SLITRK2 SLIT3	1.22e-04	90	100	5	SM00082
Domain	DUF1394	CYRIB CYFIP1	1.69e-04	4	100	2	IPR009828
Domain	DUF1394	CYRIB CYFIP1	1.69e-04	4	100	2	PF07159
Domain	LRR_1	LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3 LRMDA	1.76e-04	219	100	7	PF00560
Domain	LRRNT	MXRA5 AMIGO1 TRIL SLITRK2 SLIT3	1.82e-04	98	100	5	IPR000372
Domain	LRRNT	MXRA5 AMIGO1 TRIL SLITRK2 SLIT3	1.82e-04	98	100	5	SM00013
Domain	Ank	PPP1R12B MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	2.25e-04	228	100	7	PF00023
Domain	PTPc_motif	PALD1 DUSP4 MTMR6 PTPN13	2.81e-04	59	100	4	SM00404
Domain	Tyr_Pase_cat	PALD1 DUSP4 MTMR6 PTPN13	2.81e-04	59	100	4	IPR003595
Domain	-	MXRA5 LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3 LRMDA	3.30e-04	321	100	8	3.80.10.10
Domain	-	PPP1R12B LRRK2 MIB2 KIDINS220 SOWAHB NOTCH2 PPP1R16A	3.75e-04	248	100	7	1.25.40.20
Domain	L_dom-like	MXRA5 LRRK2 NRROS AMIGO1 TRIL SLITRK2 SLIT3 LRMDA	3.81e-04	328	100	8	IPR032675
Domain	ANK	PPP1R12B MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	4.03e-04	251	100	7	SM00248
Domain	EGF	NRG2 PTGS2 TIE1 SLIT3 NOTCH2	5.82e-04	126	100	5	PF00008
Domain	MacrogloblnA2_thiol-ester-bond	CPAMD8 A2ML1	7.78e-04	8	100	2	IPR019565
Domain	Thiol-ester_cl	CPAMD8 A2ML1	7.78e-04	8	100	2	PF10569
Domain	MacrogloblnA2_CS	CPAMD8 A2ML1	7.78e-04	8	100	2	IPR019742
Domain	A2M_N_2	CPAMD8 A2ML1	7.78e-04	8	100	2	SM01359
Domain	-	CPAMD8 A2ML1	7.78e-04	8	100	2	2.60.40.690
Domain	A2M_recep	CPAMD8 A2ML1	7.78e-04	8	100	2	SM01361
Domain	A2M	CPAMD8 A2ML1	7.78e-04	8	100	2	SM01360
Domain	Ank_2	PPP1R12B MIB2 KIDINS220 SOWAHB NOTCH2 PPP1R16A	1.05e-03	215	100	6	PF12796
Domain	A2M	CPAMD8 A2ML1	1.24e-03	10	100	2	PF00207
Domain	A2M_N_2	CPAMD8 A2ML1	1.24e-03	10	100	2	IPR011625
Domain	A2M_comp	CPAMD8 A2ML1	1.24e-03	10	100	2	IPR011626
Domain	A2M_recep	CPAMD8 A2ML1	1.24e-03	10	100	2	PF07677
Domain	A2M_comp	CPAMD8 A2ML1	1.24e-03	10	100	2	PF07678
Domain	A2M_N	CPAMD8 A2ML1	1.24e-03	10	100	2	PF01835
Domain	A2M_N	CPAMD8 A2ML1	1.24e-03	10	100	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	CPAMD8 A2ML1	1.24e-03	10	100	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	CPAMD8 A2ML1	1.24e-03	10	100	2	PS00477
Domain	A2M_N_2	CPAMD8 A2ML1	1.24e-03	10	100	2	PF07703
Domain	Macroglobln_a2	CPAMD8 A2ML1	1.24e-03	10	100	2	IPR001599
Domain	-	PALD1 DUSP4 MTMR6 PTPN13	1.51e-03	92	100	4	3.90.190.10
Domain	-	CPAMD8 A2ML1	1.81e-03	12	100	2	1.50.10.20
Domain	Prot-tyrosine_phosphatase-like	PALD1 DUSP4 MTMR6 PTPN13	1.97e-03	99	100	4	IPR029021
Domain	-	LRRK2 WDR59 NWD2 WDSUB1 DCAF4L1 PLXNB3 WDR24	2.09e-03	333	100	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	LRRK2 WDR59 NWD2 WDSUB1 DCAF4L1 PLXNB3 WDR24	2.16e-03	335	100	7	IPR015943
Domain	EGF_1	NRG2 MUC12 PTGS2 TIE1 SLIT3 NOTCH2	2.50e-03	255	100	6	PS00022
Domain	SMAD_FHA_domain	TIFAB PHF12 SMAD2	2.72e-03	52	100	3	IPR008984
Domain	EGF-like_CS	NRG2 MUC12 PTGS2 TIE1 SLIT3 NOTCH2	2.80e-03	261	100	6	IPR013032
Domain	EGF_2	NRG2 MUC12 PTGS2 TIE1 SLIT3 NOTCH2	3.02e-03	265	100	6	PS01186
Domain	WD40	LRRK2 WDR59 NWD2 WDSUB1 DCAF4L1 WDR24	3.19e-03	268	100	6	SM00320
Domain	WD40_repeat	LRRK2 WDR59 NWD2 WDSUB1 DCAF4L1 WDR24	3.44e-03	272	100	6	IPR001680
Domain	Terpenoid_cyclase/PrenylTrfase	CPAMD8 A2ML1	4.11e-03	18	100	2	IPR008930
Domain	WD40_repeat_dom	LRRK2 WDR59 NWD2 WDSUB1 DCAF4L1 WDR24	5.26e-03	297	100	6	IPR017986
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	B3GLCT MUC16 MUC12 NOTCH2 LARGE1	1.72e-05	68	67	5	M27303
Pathway	REACTOME_RND1_GTPASE_CYCLE	PKP4 PTPN13 KIDINS220 DST	4.55e-05	42	67	4	M41828
Pathway	REACTOME_RND2_GTPASE_CYCLE	PKP4 PTPN13 KIDINS220 DST	5.00e-05	43	67	4	M41827
Pathway	REACTOME_RND1_GTPASE_CYCLE	PKP4 PTPN13 KIDINS220 DST	5.00e-05	43	67	4	MM15679
Pathway	REACTOME_RND2_GTPASE_CYCLE	PKP4 PTPN13 KIDINS220 DST	5.48e-05	44	67	4	MM15678
Pathway	BIOCARTA_ATRBRCA_PATHWAY	FANCF BRCA1 RAD17	1.48e-04	22	67	3	M9703
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PALD1 PHF12 MIB2 ATP13A2 WDR59 FASN DST PCNX1 NLGN2 SIPA1L2 DNMBP PLK3 MED13 SOWAHB NOTCH2 WDR24 PPP1R16A	1.69e-08	1105	100	17	35748872
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PALD1 CPAMD8 GMEB2 NWD2 KIDINS220 PLXNB3	5.54e-07	103	100	6	10574462
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CRTC3 SORBS2 HDAC4 PKP4 ECPAS PTPN13 DST SIPA1L2 NOTCH2	5.87e-06	446	100	9	24255178
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CRTC3 SORBS2 ARHGEF28 AFTPH HDAC4 WDR59 PTPN13 DST TSC22D4 SIPA1L2 DNMBP NOTCH2	7.02e-06	861	100	12	36931259
Pubmed	COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells.	PPARG PTGS2	8.18e-06	2	100	2	23220503
Pubmed	PPAR-gamma is expressed and NF-kB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomas.	PPARG PTGS2	8.18e-06	2	100	2	16215757
Pubmed	Reciprocal expression of peroxisome proliferator-activated receptor-gamma and cyclooxygenase-2 in human term parturition.	PPARG PTGS2	8.18e-06	2	100	2	15042019
Pubmed	Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption.	PPARG PTGS2	8.18e-06	2	100	2	15550453
Pubmed	Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein.	PPARG PTGS2	8.18e-06	2	100	2	11809750
Pubmed	Comparison of fatty acid synthase and cyclooxygenase-2 immunoexpression in embryonal, benign, and malignant odontogenic tissues.	PTGS2 FASN	8.18e-06	2	100	2	30692057
Pubmed	PPARgamma pathway activation results in apoptosis and COX-2 inhibition in HepG2 cells.	PPARG PTGS2	8.18e-06	2	100	2	12800228
Pubmed	Notch2-induced COX-2 expression enhancing gastric cancer progression.	PTGS2 NOTCH2	8.18e-06	2	100	2	21976141
Pubmed	Clinical relevance of cyclooxygenase 2 and peroxisome proliferator-activated receptor γ in eyelid sebaceous gland carcinoma.	PPARG PTGS2	8.18e-06	2	100	2	26791964
Pubmed	n-3 and n-6 polyunsaturated fatty acids induce the expression of COX-2 via PPARgamma activation in human keratinocyte HaCaT cells.	PPARG PTGS2	8.18e-06	2	100	2	17459764
Pubmed	PPARγ Modulation of Cytokine-Stimulated MUC16 (CA125) Expression in Breast and Ovarian Cancer-Derived Cells.	MUC16 PPARG	8.18e-06	2	100	2	27292441
Pubmed	Role of PPARγ in COX-2 activation in mycobacterial pulmonary inflammation.	PPARG PTGS2	8.18e-06	2	100	2	22696146
Pubmed	Peroxisome proliferator-activated receptor γ is inhibited by histone deacetylase 4 in cortical neurons under oxidative stress.	HDAC4 PPARG	8.18e-06	2	100	2	21605119
Pubmed	[The expressions of PPAR-gamma, COX-2 in the lesions of patients with condyloma acuminatum and bowenoid papulosis].	PPARG PTGS2	8.18e-06	2	100	2	19627000
Pubmed	Human lung fibroblasts produce proresolving peroxisome proliferator-activated receptor-γ ligands in a cyclooxygenase-2-dependent manner.	PPARG PTGS2	8.18e-06	2	100	2	27612965
Pubmed	[Effects of LPS-induced inflammation on differentiation of orbital pre-adipocytes in thyroid-associated ophthalmopathy].	PPARG PTGS2	8.18e-06	2	100	2	21426847
Pubmed	[Expression of COX-2 and PPARg in the livers of patients with acute on chronic HBV-related liver failure and their relationship with clinic parameters].	PPARG PTGS2	8.18e-06	2	100	2	22152242
Pubmed	Nimesulide, a cyclooxygenase-2 selective inhibitor, suppresses obesity-related non-alcoholic fatty liver disease and hepatic insulin resistance through the regulation of peroxisome proliferator-activated receptor γ.	PPARG PTGS2	8.18e-06	2	100	2	27431935
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SORBS2 DCTN2 PPP1R12B PKP4 ZNF185 YJEFN3 PTGS2 CYRIB FASN NWD2 CYFIP1 KIDINS220 DST TSC22D4 SIPA1L2	1.44e-05	1431	100	15	37142655
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PHF12 SPG11 GMEB2 ECPAS DST SLIT3 PCNX1 DNMBP MED13	2.27e-05	529	100	9	14621295
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PALD1 SORBS2 TRIL KIDINS220 GSE1 SIPA1L2 PLXNB3 LARGE1	2.39e-05	407	100	8	12693553
Pubmed	No association between the PPARG gene and schizophrenia in a British population.	PPARG PTGS2	2.45e-05	3	100	2	19560328
Pubmed	Citral, a component of lemongrass oil, activates PPARα and γ and suppresses COX-2 expression.	PPARG PTGS2	2.45e-05	3	100	2	20656057
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC12	2.45e-05	3	100	2	26770020
Pubmed	High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts.	LRRK2 ATP13A2	2.45e-05	3	100	2	27399248
Pubmed	Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival.	FANCF BRCA1	2.45e-05	3	100	2	14647419
Pubmed	Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals.	PPARG PTGS2	2.45e-05	3	100	2	20649594
Pubmed	Down-regulation of LRRK2 in control and DAT transfected HEK cells increases manganese-induced oxidative stress and cell toxicity.	LRRK2 ATP13A2	2.45e-05	3	100	2	23628791
Pubmed	Estrogen receptor alpha, BRCA1, and FANCF promoter methylation occur in distinct subsets of sporadic breast cancers.	FANCF BRCA1	2.45e-05	3	100	2	17932744
Pubmed	NOTCH2 promotes osteoclast maturation and metabolism and modulates the transcriptome profile during osteoclastogenesis.	CTSK NOTCH2	2.45e-05	3	100	2	38159855
Pubmed	7beta-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes.	PPARG PTGS2	2.45e-05	3	100	2	18555503
Pubmed	The Fanconi anemia/BRCA pathway is involved in DNA interstrand cross-link repair of adriamycin-resistant leukemia cells.	FANCF BRCA1	2.45e-05	3	100	2	24996439
Pubmed	Association between mitogen-activated protein kinase kinase kinase 1 rs889312 polymorphism and breast cancer risk: evidence from 59,977 subjects.	MAP3K1 BRCA1	2.45e-05	3	100	2	20809358
Pubmed	ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition.	SIM2 BRCA1	2.45e-05	3	100	2	30531838
Pubmed	The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs).	PPARG PTGS2	2.45e-05	3	100	2	32867639
Pubmed	Osteoclast-secreted SLIT3 coordinates bone resorption and formation.	SLIT3 CTSK	2.45e-05	3	100	2	29504949
Pubmed	The role of CA-125, GLS and FASN in predicting cytoreduction for epithelial ovarian cancers.	MUC16 FASN	2.45e-05	3	100	2	32698888
Pubmed	Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms.	PTGS2 SMAD2	2.45e-05	3	100	2	18725385
Pubmed	KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.	WDR59 KICS2 WDR24	2.54e-05	20	100	3	28199306
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PKP4 PTPN13 CYFIP1 KIDINS220 DST SIPA1L2 NOTCH2 SMAD2	3.04e-05	421	100	8	36976175
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	AFTPH DCTN2 PHF12 PKP4 PKD1L1 ZNF185 ECPAS MTMR6 COMMD2 SIPA1L2 DNMBP	3.53e-05	853	100	11	28718761
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SORBS2 HDAC4 DST MED13 PLXNB3	3.83e-05	130	100	5	12421765
Pubmed	PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium.	PPARG PTGS2	4.89e-05	4	100	2	20032081
Pubmed	Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression.	BRCA1 RAD17	4.89e-05	4	100	2	25650659
Pubmed	Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations.	SPG11 ATP13A2	4.89e-05	4	100	2	20669327
Pubmed	RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells.	FANCF BRCA1	4.89e-05	4	100	2	26385482
Pubmed	The DHEA metabolite 7β-hydroxy-epiandrosterone exerts anti-estrogenic effects on breast cancer cell lines.	PPARG PTGS2	4.89e-05	4	100	2	22342541
Pubmed	Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function.	CTSK NOTCH2	4.89e-05	4	100	2	34742737
Pubmed	Gm364 coordinates MIB2/DLL3/Notch2 to regulate female fertility through AKT activation.	MIB2 NOTCH2	4.89e-05	4	100	2	34635817
Pubmed	Peroxisome proliferator-activated [corrected] receptor-gamma2 [corrected] Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes.	PPARG PTGS2	4.89e-05	4	100	2	16959787
Pubmed	Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin.	PPARG CTSK	4.89e-05	4	100	2	21876000
Pubmed	Protective effect of nonsteroidal anti-inflammatory drugs on colorectal adenomas is modified by a polymorphism in peroxisome proliferator-activated receptor delta.	PPARG PTGS2	4.89e-05	4	100	2	16344721
Pubmed	Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells.	PPARG PTGS2	4.89e-05	4	100	2	15331599
Pubmed	Structural imaging in the presymptomatic stage of genetically determined parkinsonism.	LRRK2 ATP13A2	4.89e-05	4	100	2	20483373
Pubmed	Differential Role of the RAC1-Binding Proteins FAM49b (CYRI-B) and CYFIP1 in Platelets.	CYRIB CYFIP1	4.89e-05	4	100	2	38391912
Pubmed	PPAR-γ, RXR, VDR, and COX-2 Expressions in gingival tissue samples of healthy individuals, periodontitis and peri-implantitis patients.	PPARG PTGS2	4.89e-05	4	100	2	31929206
Pubmed	Protection against influenza-induced Acute Lung Injury (ALI) by enhanced induction of M2a macrophages: possible role of PPARγ/RXR ligands in IL-4-induced M2a macrophage differentiation.	PPARG PTGS2	4.89e-05	4	100	2	36052067
Pubmed	Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer.	PPARG PTGS2	4.89e-05	4	100	2	14604894
Pubmed	Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma.	HDAC4 PPARG	4.89e-05	4	100	2	17218271
Pubmed	Peroxisome proliferator-activated receptor gamma ligands enhance human B cell antibody production and differentiation.	PPARG PTGS2	4.89e-05	4	100	2	19915048
Pubmed	Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer.	PPARG FASN	4.89e-05	4	100	2	27357679
Pubmed	TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage.	BRCA1 SMAD2	8.14e-05	5	100	2	15735739
Pubmed	CD36-mediated cholesterol efflux is associated with PPARgamma activation via a MAPK-dependent COX-2 pathway in macrophages.	PPARG PTGS2	8.14e-05	5	100	2	19377069
Pubmed	Functional interaction between FOXO3a and ATM regulates DNA damage response.	BRCA1 RAD17	8.14e-05	5	100	2	18344987
Pubmed	Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.	MAP3K1 BRCA1	8.14e-05	5	100	2	18355772
Pubmed	The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways.	NOTCH2 SMAD2	8.14e-05	5	100	2	28747678
Pubmed	Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.	PPARG FASN	8.14e-05	5	100	2	26670611
Pubmed	Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.	FREM2 SLIT3	8.14e-05	5	100	2	23536828
Pubmed	An MMTV integration site maps near the distal end of mouse chromosome 11.	FASN BRCA1	8.14e-05	5	100	2	9096121
Pubmed	Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.	BRCA1 RAD17	8.14e-05	5	100	2	15485898
Pubmed	Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARgamma : Possible relevance to human fibrotic disorders.	PPARG PTGS2	8.14e-05	5	100	2	12397176
Pubmed	Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.	FEZF2 GSE1 PCNX1	9.78e-05	31	100	3	27321927
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	SPG11 WDR59 PTPN13 KIDINS220 DST NOTCH2 SMAD2 WDR24	1.07e-04	504	100	8	34432599
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PKP4 PTPN13 CYFIP1 KIDINS220 DST LRMDA NOTCH2	1.12e-04	377	100	7	38117590
Pubmed	Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes.	PPARG PTGS2	1.22e-04	6	100	2	17307204
Pubmed	Breast cancer susceptibility variants alter risks in familial disease.	MAP3K1 BRCA1	1.22e-04	6	100	2	19617217
Pubmed	5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids.	PPARG PTGS2	1.22e-04	6	100	2	21307302
Pubmed	NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.	CTSK NOTCH2	1.22e-04	6	100	2	29149593
Pubmed	The polymorphism IL-1beta T-31C is associated with a longer overall survival in patients with multiple myeloma undergoing auto-SCT.	PPARG PTGS2	1.22e-04	6	100	2	18997828
Pubmed	Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study.	PPARG PTGS2	1.22e-04	6	100	2	18164040
Pubmed	Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes.	PPARG PTGS2	1.22e-04	6	100	2	20448152
Pubmed	Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages.	PPARG PTGS2	1.22e-04	6	100	2	18208815
Pubmed	Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.	HDAC4 DST	1.22e-04	6	100	2	20887891
Pubmed	Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.	MUC16 PPARG PTGS2 FANCF BRCA1	1.36e-04	170	100	5	19064572
Pubmed	Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.	DST BRCA1 NOTCH2 SMAD2 RAD17	1.64e-04	177	100	5	22560297
Pubmed	Regulation of Neurogenesis in Mouse Brain by HMGB1.	LHX6 AMIGO1 NOTCH2	1.67e-04	37	100	3	32708917
Pubmed	Sporadic Hirschsprung Disease: Mutational Spectrum and Novel Candidate Genes Revealed by Next-generation Sequencing.	PTPN13 AGL	1.70e-04	7	100	2	29093530
Pubmed	Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4.	CRTC3 HDAC4	1.70e-04	7	100	2	24768298
Pubmed	Inflammation-related gene polymorphisms and colorectal adenoma.	PPARG PTGS2	1.70e-04	7	100	2	16775170
Pubmed	The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.	WDR59 WDR24	1.70e-04	7	100	2	31915252
Pubmed	Conserved expression domains for genes upstream and within the HoxA and HoxD clusters suggests a long-range enhancer existed before cluster duplication.	TRIL HOXA13	1.70e-04	7	100	2	15509224
Pubmed	The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway.	WDR59 WDR24	1.70e-04	7	100	2	26972053
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	CRTC3 RBM4 PKP4 GSE1 NOTCH2	1.78e-04	180	100	5	35198878
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	PALD1 CRTC3 SORBS2 PKD1L1 LRRK2 CYRIB RNF214 FREM2 ARSA SIPA1L2 MED13 PPP1R16A	1.94e-04	1215	100	12	15146197
Pubmed	14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.	HDAC4 GART FASN AGL FLAD1	2.07e-04	186	100	5	14744259
Pubmed	A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).	MAP3K1 NOTCH2	2.27e-04	8	100	2	19330030
Interaction	KICS2 interactions	WDR59 FASN KICS2 WDR24	5.07e-07	14	98	4	int:KICS2
Interaction	ITFG2 interactions	WDR59 FASN KICS2 WDR24	1.31e-05	30	98	4	int:ITFG2
Interaction	PARD3 interactions	HDAC4 PKP4 PTPN13 KIDINS220 DST SIPA1L2 DNMBP NOTCH2 SMAD2	1.49e-05	298	98	9	int:PARD3
Interaction	AFDN interactions	SORBS2 PKP4 PTPN13 KIDINS220 DST SIPA1L2 DNMBP NOTCH2 SMAD2	3.57e-05	333	98	9	int:AFDN
Interaction	MAPK3 interactions	HDAC4 RBM4 DUSP4 LRRK2 PTGS2 MAP3K1 FASN GSE1 BRCA1 SMAD2	3.88e-05	421	98	10	int:MAPK3
Interaction	SZT2 interactions	WDR59 FASN KICS2 WDR24	4.64e-05	41	98	4	int:SZT2
Interaction	WDR24 interactions	WDR59 FASN KICS2 WDR24	5.61e-05	43	98	4	int:WDR24
Interaction	EEF1AKMT2 interactions	SPG11 PTPN13 GSE1 RAD17	5.61e-05	43	98	4	int:EEF1AKMT2
Interaction	CASTOR2 interactions	WDR59 DST WDR24	5.96e-05	16	98	3	int:CASTOR2
Interaction	RYK interactions	PKP4 FREM2 CYFIP1 KIDINS220 DST NLGN2 PCDHGC3	7.95e-05	212	98	7	int:RYK
GeneFamily	Ankyrin repeat domain containing	PPP1R12B MIB2 KIDINS220 ASB3 SOWAHB NOTCH2 PPP1R16A	1.85e-05	242	62	7	403
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CPAMD8 A2ML1	4.10e-04	9	62	2	1234
GeneFamily	Parkinson disease associated genes	LRRK2 ATP13A2	1.35e-03	16	62	2	672
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCF BRCA1	2.11e-03	20	62	2	548
GeneFamily	CD molecules\|Mucins	MUC16 MUC12	2.33e-03	21	62	2	648
Coexpression	GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN	PPP1R12B RUBCNL ZNF185 GPR63 LHX6 PTGS2 SLITRK2 VNN2	9.82e-07	199	100	8	M4474
Coexpression	GSE22886_NEUTROPHIL_VS_DC_UP	RUBCNL LHX6 PTGS2 SLITRK2 BRCA1 VNN2 B3GAT1 PCDHGC3	9.82e-07	199	100	8	M4464
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LILRA1 TIFAB RUBCNL TMEM63C P2RY8 PPARG IRAG2 MS4A14	1.03e-08	187	100	8	23be50d81f4404a609dea821e1a66d221c0e0615
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 P2RY8 NRG2 PPARG GSE1 TIE1 LRMDA	2.64e-07	192	100	7	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 P2RY8 NRG2 PPARG GSE1 TIE1 LRMDA	2.74e-07	193	100	7	52e918884877b6659cdca0496390e440f73694a9
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|LA / Chamber and Cluster_Paper	MXRA5 SORBS2 PPP1R12B TMEM63C KICS2 LARGE1	1.02e-06	147	100	6	8970eb6b82589f39439c61a57d999661ec8342de
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 PKP4 LRRK2 P2RY8 MUC16 PTGS2	1.10e-06	149	100	6	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 PKP4 LRRK2 P2RY8 MUC16 PTGS2	1.14e-06	150	100	6	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PKP4 DUSP4 PKD1L1 NRROS B3GAT1 FILIP1L	3.85e-06	185	100	6	e06a784a297f357f3f8e761c24fa70722048ab42
ToppCell	MS-CD8-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	AFTPH PKP4 DUSP4 AMIGO1 WDR24 PPP1R16A	4.23e-06	188	100	6	2f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCell	Non-neuronal-Non-dividing-OPC-OPC\|World / Primary Cells by Cluster	LRRK2 MAP3K1 SLITRK2 ASB3 TSC22D4 PCDHGC3	4.36e-06	189	100	6	ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCell	Non-neuronal-Non-dividing-OPC\|World / Primary Cells by Cluster	LRRK2 MAP3K1 SLITRK2 ASB3 TSC22D4 PCDHGC3	4.36e-06	189	100	6	13848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCell	Non-neuronal-Non-dividing-OPC-OPC-30\|World / Primary Cells by Cluster	LRRK2 MAP3K1 SLITRK2 ASB3 TSC22D4 PCDHGC3	4.36e-06	189	100	6	313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 LHX6 GSE1 TIE1 IRAG2 LRMDA	4.49e-06	190	100	6	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORBS2 LRRK2 FREM2 FASN PTPN13 LARGE1	4.63e-06	191	100	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC12 PTGS2 AMIGO1 FANCF FREM2 PLXNB3	5.37e-06	196	100	6	ef650ff106a76c1e926e13c7f002fbc452cc48ae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 PKP4 SIM2 CYRIB FREM2 PTPN13	5.37e-06	196	100	6	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM63C MUC12 PPARG IRAG2 PLK3 NOTCH2	5.69e-06	198	100	6	a631be84e29c277216d89ec6265bd43e87c1dc86
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MXRA5 TRIL DST SLIT3 CTSK FILIP1L	5.86e-06	199	100	6	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MXRA5 TRIL DST SLIT3 CTSK FILIP1L	5.86e-06	199	100	6	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PKD1L1 TRIL TSC22D4 LRMDA PLXNB3	1.56e-05	139	100	5	a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell	Adult-Mesenchymal-chondrocyte-D122\|Adult / Lineage, Cell type, age group and donor	SIM2 FASN SLITRK2 A2ML1 SLIT3	2.11e-05	148	100	5	81a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCell	356C-Myeloid-Dendritic-pDC\|356C / Donor, Lineage, Cell class and subclass (all cells)	TIFAB RUBCNL ATP13A2 PCDHGC3 WDR24	2.71e-05	156	100	5	d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PALD1 HDAC4 PPARG HOXA13 FANCF	2.88e-05	158	100	5	f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFTPH PPARG KIDINS220 CTSK PLXNB3	3.16e-05	161	100	5	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SORBS2 AMIGO1 FREM2 PTPN13 KICS2	3.25e-05	162	100	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LILRA1 RUBCNL P2RY8 AGL MED13	3.45e-05	164	100	5	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SORBS2 AMIGO1 FREM2 PTPN13 KICS2	3.65e-05	166	100	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	LILRA1 SORBS2 GART GMEB2 PTPN13	3.98e-05	169	100	5	ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LHX6 DST TIE1 PCNX1 FILIP1L	4.09e-05	170	100	5	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	RUBCNL LRRK2 PTGS2 CYRIB VNN2	4.32e-05	172	100	5	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	wk_20-22-Epithelial-PNS\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SLITRK2 B3GAT1 TSC22D4 SIPA1L2 PLXNB3	4.45e-05	173	100	5	17b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 RUBCNL LRRK2 SLITRK2 TSC22D4	4.57e-05	174	100	5	667035a11b68745fa8446d6c68214713be42710f
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PALD1 DUSP4 PPARG CYFIP1 PLK3	4.70e-05	175	100	5	6374ab186d7ccf7f6dfb858267edba8962789e15
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SORBS2 LHX6 DST TIE1 FILIP1L	5.09e-05	178	100	5	0139b42494c1186390b12106dea7957e2b6717c2
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DUSP4 MUC12 PPARG MTMR6 CYFIP1	5.09e-05	178	100	5	8151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	PKP4 LRRK2 P2RY8 MUC16 PTGS2	5.23e-05	179	100	5	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUBCNL NRG2 NLGN2 WDSUB1 PLXNB3	5.23e-05	179	100	5	2c3abd646d2c8992e8ff76a824eab5beba8ba4c6
ToppCell	Control-Myeloid-Monocytes,_Macrophages\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LILRA1 TIFAB RUBCNL P2RY8 PTGS2	5.23e-05	179	100	5	a79a244bf8ecc333d034b2eb2de554d3310ca6de
ToppCell	Control-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LILRA1 TIFAB RUBCNL P2RY8 PTGS2	5.23e-05	179	100	5	c4ff8b191ed0f6dc2dd784869f6f2c62e170a7db
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUBCNL NRG2 NLGN2 WDSUB1 PLXNB3	5.23e-05	179	100	5	6eb84fe9691ad40127b2d1f1c672428333c8fab4
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SLITRK2 DST B3GAT1 TSC22D4	5.37e-05	180	100	5	b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LILRA1 TIFAB P2RY8 IRAG2 MS4A14	5.51e-05	181	100	5	f737f2b1f35747b81fdd8996e289bde5c290af61
ToppCell	Control-Myeloid\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LILRA1 TIFAB RUBCNL P2RY8 PTGS2	5.51e-05	181	100	5	25170e5285996cc80337d5f86a0255569861ae77
ToppCell	facs-BAT-Fat-18m\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRROS CYRIB MAP3K1 TSC22D4 NOTCH2	5.66e-05	182	100	5	efc335f4e566533cfbcd17262bd94ae64fa2e117
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 B3GLCT GPR63 NWD2 LRMDA	5.66e-05	182	100	5	1647367b75b4b107af06bb934394168230cfd7c2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORBS2 LRRK2 FREM2 PTPN13 LARGE1	5.80e-05	183	100	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PKP4 DUSP4 PKD1L1 NRROS FILIP1L	5.80e-05	183	100	5	f142b320023eef00b48d4820c46214c9794d37e7
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DUSP4 LRRK2 NRROS IRAG2 DNMBP	5.80e-05	183	100	5	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 LHX6 GSE1 TIE1 SIPA1L2	5.96e-05	184	100	5	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	SORBS2 LRRK2 FREM2 FASN PTPN13	5.96e-05	184	100	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 TIFAB RUBCNL DUSP4 DST	5.96e-05	184	100	5	667846c422cfa27e949a24844a305df859cb6760
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	LILRA1 LRRK2 PCNX1 DNMBP NOTCH2	5.96e-05	184	100	5	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	droplet-Mammary_Gland-nan-18m-Lymphocytic-B_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUBCNL DUSP4 NRROS CYRIB MAP3K1	5.96e-05	184	100	5	73ddf9d647d61381bab1e9c0d983736b6d390c15
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	31df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	b95be984e308d4f9061274a35995ec558d434e74
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	8f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	95c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SLITRK2 DST TSC22D4 PLXNB3	6.27e-05	186	100	5	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	b70cd94c651b56dcf2e55554533a5f1130845390
ToppCell	COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease group, lineage and cell class	PALD1 TIFAB RUBCNL ATP13A2 PCDHGC3	6.27e-05	186	100	5	3db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 ARHGEF28 LHX6 ATP13A2 TIE1	6.27e-05	186	100	5	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	CPAMD8 ARHGEF28 TIE1 SIPA1L2 LRMDA	6.43e-05	187	100	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	RUBCNL LRRK2 NRROS DNMBP LARGE1	6.43e-05	187	100	5	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 NRROS MAP3K1 NOTCH2 FILIP1L	6.43e-05	187	100	5	b51af2824e65734f333b1325117f4a2e88b17c23
ToppCell	facs-Spleen-nan-3m-Lymphocytic-B_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRK2 NRROS MAP3K1 NOTCH2 FILIP1L	6.43e-05	187	100	5	3ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCell	Control-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	LILRA1 LRRK2 P2RY8 VNN2 DNMBP	6.59e-05	188	100	5	47126c371a242c937499fd278a74a882df8f759c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUSP4 P2RY8 MAP3K1 PTPN13 PLK3	6.76e-05	189	100	5	284f39dfacec76004daae9dd5317fb7b1f04fa99
ToppCell	IPF-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	LILRA1 LRRK2 P2RY8 VNN2 DNMBP	6.76e-05	189	100	5	ad7bb3a7de8e48c145e4382f90d30bb2159c2b76
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUSP4 LRRK2 NRROS IRAG2 DNMBP	6.93e-05	190	100	5	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 P2RY8 GSE1 TIE1 LRMDA	7.11e-05	191	100	5	f663131a4810584c5854bd64ee7991a237b7707f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 LRRK2 FREM2 PTPN13 LARGE1	7.11e-05	191	100	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DUSP4 CYFIP1 SIPA1L2 CTSK FILIP1L	7.11e-05	191	100	5	be2fe2583bdcee0b35c43a347da9c4adb93e30e0
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	MXRA5 TRIL DST SLIT3 FILIP1L	7.11e-05	191	100	5	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	DUSP4 CYFIP1 SIPA1L2 CTSK FILIP1L	7.11e-05	191	100	5	4cebaf31d4f09f4ab273a819ad5cbff7d9a9b341
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LILRA1 TIFAB P2RY8 IRAG2 MS4A14	7.11e-05	191	100	5	367d300da3925e0a329271b5f19483a37265a878
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	CPAMD8 LRRK2 FREM2 PTPN13 LARGE1	7.11e-05	191	100	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	MXRA5 TRIL DST SLIT3 FILIP1L	7.11e-05	191	100	5	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	COPD-Myeloid-cDC2\|World / Disease state, Lineage and Cell class	PALD1 DUSP4 NRROS DNMBP FILIP1L	7.11e-05	191	100	5	4e4887175200a57e1b041f2f131e3df774df3509
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SORBS2 LRRK2 FREM2 PTPN13 LARGE1	7.11e-05	191	100	5	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC1\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TIFAB RUBCNL LRRK2 P2RY8 IRAG2	7.11e-05	191	100	5	9774d423e448ec2d415261e4ad386a81558129b3
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	LRRK2 FREM2 FASN PTPN13 LARGE1	7.28e-05	192	100	5	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LRRK2 FREM2 PTPN13 LRMDA LARGE1	7.28e-05	192	100	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 SLITRK2 DST TSC22D4 PLXNB3	7.46e-05	193	100	5	3ea6b103e35bbb276e95301999618558fa3e38b1
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LRRK2 FREM2 FASN PTPN13 LARGE1	7.46e-05	193	100	5	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 PKP4 LHX6 DST TIE1	7.46e-05	193	100	5	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 PKP4 LHX6 DST TIE1	7.46e-05	193	100	5	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	Control-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	LILRA1 LRRK2 VNN2 DNMBP NOTCH2	7.46e-05	193	100	5	3479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	LRRK2 FREM2 FASN PTPN13 LARGE1	7.46e-05	193	100	5	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LRRK2 FREM2 FASN PTPN13 LARGE1	7.46e-05	193	100	5	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MAP3K1 TRIL DST GSE1 SLIT3	7.65e-05	194	100	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 ARHGEF28 LRRK2 SIM2 MAP3K1	7.65e-05	194	100	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 PKP4 SIM2 FREM2 PTPN13	7.65e-05	194	100	5	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	SORBS2 B3GLCT PPP1R12B SLIT3 LARGE1	7.65e-05	194	100	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LRRK2 FREM2 FASN PTPN13 LARGE1	7.65e-05	194	100	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 PKP4 LHX6 DST TIE1	7.65e-05	194	100	5	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	distal-Hematologic-Nonclassical_Monocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LILRA1 LRRK2 MAP3K1 IRAG2 NOTCH2	7.83e-05	195	100	5	6f417bb464b8ae6a50bbab5db5a6d5760c02122f
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	PALD1 LILRA1 MAP3K1 VNN2 IRAG2	7.83e-05	195	100	5	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SORBS2 PKP4 LHX6 TIE1 LRMDA	7.83e-05	195	100	5	527a5a50d6e2cbbbd64d11609e5cde2e33f14797
ToppCell	Control-Myeloid-ncMonocyte\|Control / Disease state, Lineage and Cell class	LILRA1 LRRK2 VNN2 DNMBP NOTCH2	7.83e-05	195	100	5	fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	LILRA1 LRRK2 VNN2 DNMBP NOTCH2	7.83e-05	195	100	5	b4444b67a709e82b8e2ee510924c3152cb88b051
Drug	(-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; PC3; HT_HG-U133A	GART NRG2 ATP13A2 WDR59 FLAD1 PCNX1 DNMBP NOTCH2	2.47e-06	196	100	8	5833_DN
Disease	amyotrophic lateral sclerosis (is_marker_for)	HDAC4 LRRK2 PTGS2	1.26e-04	29	99	3	DOID:332 (is_marker_for)
Disease	adenocarcinoma (implicated_via_orthology)	PTGS2 NOTCH2	2.31e-04	7	99	2	DOID:299 (implicated_via_orthology)
Disease	colon cancer (is_implicated_in)	PPARG PTPN13 BRCA1	2.41e-04	36	99	3	DOID:219 (is_implicated_in)
Disease	cleft lip	ARHGEF28 NUP210L MUC16 WDR59 DST BRCA1	4.00e-04	284	99	6	EFO_0003959
Disease	microfibrillar-associated protein 2 measurement	ATP13A2 A2ML1	6.01e-04	11	99	2	EFO_0801801
Disease	Mouth Diseases	PTGS2 BRCA1	7.20e-04	12	99	2	C0026636
Disease	Parkinson disease	LRRK2 MUC12 CYRIB FANCF SIPA1L2 MED13	7.59e-04	321	99	6	MONDO_0005180
Disease	ovarian cancer (is_implicated_in)	MUC16 BRCA1 SMAD2	8.93e-04	56	99	3	DOID:2394 (is_implicated_in)
Disease	polycystic kidney disease (implicated_via_orthology)	PPARG PTGS2	9.88e-04	14	99	2	DOID:0080322 (implicated_via_orthology)
Disease	Bladder Neoplasm	HDAC4 YJEFN3 PTGS2 NOTCH2	1.29e-03	140	99	4	C0005695
Disease	Barrett Epithelium	PPARG PTGS2	1.30e-03	16	99	2	C1258085
Disease	Barrett Esophagus	PPARG PTGS2	1.30e-03	16	99	2	C0004763
Disease	Malignant neoplasm of urinary bladder	HDAC4 YJEFN3 PTGS2 NOTCH2	1.32e-03	141	99	4	C0005684
Disease	breast carcinoma (is_marker_for)	BRCA1 PLK3 SMAD2	1.44e-03	66	99	3	DOID:3459 (is_marker_for)
Disease	diabetic neuropathy (biomarker_via_orthology)	LRRK2 PTGS2	1.47e-03	17	99	2	DOID:9743 (biomarker_via_orthology)
Disease	Benign Neoplasm	PTGS2 FASN BRCA1	1.57e-03	68	99	3	C0086692
Disease	Neoplasms	PTGS2 FASN BRCA1	1.57e-03	68	99	3	C0027651
Disease	bipolar disorder, sex interaction measurement	SLIT3 SIPA1L2	1.65e-03	18	99	2	EFO_0008343, MONDO_0004985
Disease	hippuric acid measurement	RFX6 A2ML1	1.84e-03	19	99	2	EFO_0010496
Disease	stomach cancer (is_implicated_in)	MAP3K1 GSE1 BRCA1	1.85e-03	72	99	3	DOID:10534 (is_implicated_in)
Disease	cardiovascular system disease (is_implicated_in)	PPARG PTGS2	2.24e-03	21	99	2	DOID:1287 (is_implicated_in)
Disease	Parkinson disease	LRRK2 ATP13A2	2.46e-03	22	99	2	cv:C0030567
Disease	idiopathic pulmonary fibrosis (is_marker_for)	PTGS2 SMAD2	2.69e-03	23	99	2	DOID:0050156 (is_marker_for)
Disease	blood zinc measurement	SORBS2 MTMR6	2.69e-03	23	99	2	EFO_0007584
Disease	Nerve Degeneration	LRRK2 PPARG ATP13A2	2.77e-03	83	99	3	C0027746
Disease	Giant Cell Glioblastoma	PPARG CTSK NOTCH2	2.87e-03	84	99	3	C0334588
Disease	Schizophrenia	HDAC4 LHX6 PTGS2 CYFIP1 BRCA1 SLIT3 B3GAT1 NLGN2 CTSK	2.90e-03	883	99	9	C0036341
Disease	prostate carcinoma	DUSP4 RFX6 GMEB2 SIM2 MAP3K1 B3GAT1 CTSK SOWAHB SMAD2	3.08e-03	891	99	9	EFO_0001663
Disease	Fanconi Anemia	FANCF BRCA1	3.18e-03	25	99	2	C0015625
Disease	skin aging measurement	HDAC4 PPARG MAP3K1 KIDINS220	3.28e-03	181	99	4	EFO_0008006

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRSAVSPDLHITPIY	PKP4	401	Q99569
DTLPTIHVVTPTYSR	B3GAT1	81	Q9P2W7
PLSHSRSNDTLYIPE	CTSK	96	P43235
PHSLPSYTALLDLSH	AMIGO1	56	Q86WK6
LPLLPHFSVTYSRNS	B3GLCT	111	Q6Y288
AAYDISVLPRTDSHP	ALX3	226	O95076
PLSTHSTEYNLDSVP	AFTPH	211	Q6ULP2
LSGVRYPPELSHSSL	GSE1	301	Q14687
PTSPRSLTLTIHTSY	A2ML1	1341	A8K2U0
APTSPLGHLTSEYDT	DNMBP	356	Q6XZF7
TGTPPDSSLVTYELH	DCTN2	196	Q13561
YPSTVEIHPDASSLT	GMEB2	441	Q9UKD1
YSPERLPLSSSHLHV	NWD2	956	Q9ULI1
STSLDPYDRHLLPTS	RBM4	266	Q9BWF3
YSHRVSLPTSPGILA	RUBCNL	141	Q9H714
SPRLPSHLSEYERDT	RAD17	416	O75943
NESHVETTYLPLPSS	RFX6	591	Q8HWS3
HVSVISSIRSLPPYS	RFX6	821	Q8HWS3
AHPELYRLPVTLSSA	PALD1	456	Q9ULE6
SPLARTDLTYPVHAL	P2RY8	156	Q86VZ1
HTLPTETSPSVYPLS	ARHGEF28	416	Q8N1W1
ATIHLPPSNRYETLL	CYFIP1	736	Q7L576
PALHEITSSSATPYR	MUC16	10346	Q8WXI7
VTLSPVDSLESPHTY	NOTCH2	2146	Q04721
NELPHTELSSQTPYT	KIDINS220	1311	Q9ULH0
SLSPLESQAHSPRYT	LARGE1	41	O95461
TLVTSRHPALSPVYL	FANCF	261	Q9NPI8
SLFPGTHLTPYLSTS	HDAC4	386	P56524
THLTPYLSTSPLERD	HDAC4	391	P56524
RHYTPLPSASRELTS	LRMDA	156	Q9H2I8
PLYSSESHRFTVLEP	MTMR6	471	Q9Y217
PIFDYSPRLSALLSH	DST	2216	Q03001
PILSHPTGTLESYLD	FREM2	941	Q5SZK8
AHLLRTIPSPYSASE	DCAF4L1	346	Q3SXM0
ELNLTPASSPARHTY	TMEM63C	751	Q9P1W3
TVFPSDHIPSRYLLL	ECPAS	506	Q5VYK3
STSVRFYPHDVLSLP	PCNX1	916	Q96RV3
HFTYQDPVLLSLSPR	PLXNB3	921	Q9ULL4
RTILSELAPSLPSYH	COMMD2	111	Q86X83
SPHSERYVSALTTPA	NRG2	586	O14511
LTTPARLSPVDFHYS	NRG2	596	O14511
CHPLRYPSIVTSSLI	OR56B1	136	Q8NGI3
YLLVPSSLSDHRPVI	LRRK2	1666	Q5S007
YVLTSRSHLIDSPPT	PTGS2	101	P35354
SRLPSALSDDIHYTP	LHX6	291	Q9UPM6
ASSSLTAHEPPLLYD	ARSA	416	P15289
VSSLYRTPGPSLHAD	PCDHGC3	731	Q9UN70
YSSRFHHPILSPLES	KICS2	171	Q96MD2
ESGPHDLTETSYLPR	BRCA1	1541	P38398
SYTVEPDPRSRHLAL	ATP13A2	811	Q9NQ11
SDSYISQLPLPRSLH	ASB3	481	Q9Y575
TLEITSPTTESPHSY	FILIP1L	916	Q4L180
DLTNLHYSTPLPASL	CRTC3	276	Q6UUV7
TTYALTLLRSPAAPE	CPAMD8	1316	Q8IZJ3
TVLTAFPYRPHSSLL	MS4A14	21	Q96JA4
EYSSLPLPRHTSSTD	IRAG2	81	Q12912
QHPDLSPLLRYSFET	GPR63	36	Q9BZJ6
LTSTPYSPTQHLERE	CYRIB	111	Q9NUQ9
SPHPLLQLSYTATDR	FASN	1261	P49327
SLVPSSARLHYGTDP	FLAD1	221	Q8NFF5
SAPSSLPYLHSPITT	DUSP4	376	Q13115
LHTELFTTTTRLPPY	NLGN2	611	Q8NFZ4
PSSSRYLHTPRLTVS	PKD1L1	1946	Q8TDX9
DSTAYPPSELLSGHL	FEZF2	176	Q8TBJ5
SLQPYPLLESLSLHS	NRROS	76	Q86YC3
SHSPLTPGLAIYSVR	NUP210L	1741	Q5VU65
PIYHTRELPTSSAIS	PTPN13	361	Q12923
DRYETAHSRPVTLSP	MIB2	131	Q96AX9
YSHELSSPVDSPSSL	MAP3K1	501	Q13233
RPSSPALYFTHDASL	TSC22D4	261	Q9Y3Q8
LSSNPYLLSHPSDSL	LILRA1	401	O75019
SSISTPHYEDIPFTR	PPARG	71	P37231
HLYSSPTDSTDPRRL	PHF12	551	Q96QT6
SVSYQLSPLDSTTPH	PPP1R16A	431	Q96I34
SLSVSPSSYPELHTE	SLITRK2	601	Q9H156
LQPHSESSDLLYTPS	SIM2	421	Q14190
DILFSTTPPYHSTLP	SIPA1L2	1516	Q9P2F8
SHARPPSTSLIYDSD	MED13	761	Q9UHV7
PELLTPSSLHYSTLQ	SOWAHB	286	A6NEL2
LPDVVSHPSDASSYR	HOXA13	306	P31271
STPSRSAYDEPHLLV	MSANTD4	191	Q8NCY6
PIPHSYSSDRIHSLS	SORBS2	1011	O94875
LSLPRRYPHTSATFL	C1orf105	31	O95561
GHVRLVYDSLSSPPT	SLIT3	1211	O75094
IYHLIQSLSPFDPSR	SPG11	1146	Q96JI7
LHLTYLKSTPPTLET	RNF214	376	Q8ND24
LSEVDSHPLSSLAYP	VNN2	301	O95498
SSHLLEEATLVYPAS	ZNF750	346	Q32MQ0
HYTLPASLSLPARQL	PLK3	276	Q9H4B4
ILTELPPLDDYTHSI	SMAD2	186	Q15796
PISTVRLHYRPQDST	TIE1	476	P35590
KTSSLPSPHDVLTYS	TRIL	51	Q7L0X0
EPTIFYPTRSLDLLH	YJEFN3	146	A6XGL0
TVLRVSLYHPTLGPS	TIFAB	6	Q6ZNK6
LTPTRIYSHSLLPVL	GART	656	P22102
TEPTPRSLSALSAYH	WDR59	566	Q6PJI9
LLSVSHALYDSRLPP	WDR24	616	Q96S15
LYSLRDFTELPHSPL	WDSUB1	36	Q8N9V3
HIYIPAPASELDSSS	ZNF185	556	O15231
PIVHRSAYDALPSTT	AGL	631	P35573
TSALVEEPTSYHSSP	MUC12	4791	Q9UKN1
SPTLHTLDTVYEKPT	MXRA5	921	Q9NR99
PSTSRPSLYTSSHLL	PPP1R12B	736	O60237