Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA1 GRIA2 GRIA3 GRIA4

1.08e-0941164GO:0004971
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

9.04e-09271166GO:0008066
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

3.55e-08171165GO:0004970
GeneOntologyMolecularFunctionprotein kinase activity

TRIB2 EPHA6 ERN1 PPM1D CDK11A ALPK1 NEK9 PRKD3 STK3 PHKA1 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24 TRIB1

6.85e-0860011617GO:0004672
GeneOntologyMolecularFunctionJUN kinase activity

MAPK8 MAPK9 MAPK10

1.91e-0731163GO:0004705
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.36e-07241165GO:0099507
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TRIB2 EPHA6 ERN1 PPM1D CDK11A ALPK1 NEK9 PRKD3 STK3 PHKA1 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24 TRIB1

7.19e-0770911617GO:0016773
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TRIB2 EPHA6 ERN1 PPM1D CDK11A ALPK1 CMAS NEK9 PRKD3 STK3 PHKA1 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24 TRIB1 REV1

1.88e-0693811619GO:0016772
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

ERN1 PPM1D CDK11A ALPK1 NEK9 PRKD3 STK3 PHKA1 NEK2 MAPK8 MAPK9 MAPK10 STK24

1.97e-0644611613GO:0004674
GeneOntologyMolecularFunctionkinase activity

TRIB2 EPHA6 ERN1 PPM1D CDK11A ALPK1 NEK9 PRKD3 STK3 PHKA1 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24 TRIB1

1.99e-0676411617GO:0016301
GeneOntologyMolecularFunctionamyloid-beta binding

CACNA1B APBB2 GRIA1 GRIA2 GRIA3 GRIA4 SCARB1

2.18e-061021167GO:0001540
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1B SCN11A TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D ATP5MG PKD2 CACNA1G KCNT1

2.71e-0645911613GO:0005216
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1B SCN11A TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 GRIN2D ATP5MG SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

3.53e-0662711615GO:0022890
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

4.90e-06751166GO:0098960
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1B SCN11A TRPC4 GRIA1 GRIA2 GRIA3 GRIN2D ATP5MG PKD2 CACNA1G KCNT1

5.16e-0634311611GO:0005261
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1B SCN11A SLC37A3 TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 GRIN2D ATP5MG SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

8.00e-0675811616GO:0015318
GeneOntologyMolecularFunctionprotein serine kinase activity

ERN1 CDK11A ALPK1 NEK9 PRKD3 STK3 NEK2 MAPK8 MAPK9 MAPK10 STK24

8.82e-0636311611GO:0106310
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1B TRPC4 GRIA1 GRIA3 GRIN2D PKD2 CACNA1G

1.04e-051291167GO:0005262
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIA1 GRIA3 GRIN2D

1.05e-0581163GO:0022849
GeneOntologyMolecularFunctionchannel activity

CACNA1B SCN11A TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D ATP5MG PKD2 CACNA1G KCNT1

1.15e-0552511613GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1B SCN11A TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D ATP5MG PKD2 CACNA1G KCNT1

1.18e-0552611613GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1B SCN11A TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D ATP5MG SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

1.40e-0579311616GO:0015075
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1B SCN11A TRPC4 GRIA1 GRIA2 GRIA3 GRIN2D SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

1.70e-0546511612GO:0046873
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.00e-05571165GO:1904315
GeneOntologyMolecularFunctiongated channel activity

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D PKD2 CACNA1G KCNT1

2.55e-0533411610GO:0022836
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.57e-05601165GO:0099529
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.58e-051001166GO:0030594
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1B TRPC4 GRIA1 GRIA3 GRIN2D PKD2 CACNA1G

2.88e-051511167GO:0015085
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIA1 GRIA3 GRIN2D PKD2

3.01e-05311164GO:0099604
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1B SCN11A TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIN2D ATP5MG SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

3.13e-0566411614GO:0008324
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

3.79e-05651165GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

3.79e-05651165GO:0022824
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

8.59e-05771165GO:0005230
GeneOntologyMolecularFunctionMAP kinase activity

MAPK8 MAPK9 MAPK10

1.01e-04161163GO:0004707
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D PKD2 KCNT1

1.36e-041931167GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D PKD2 KCNT1

1.54e-041971167GO:0022834
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

GRIA1 GRIA2 GRIA3 GRIN2D PKD2 KCNT1

1.68e-041401166GO:0099094
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRIA1 GRM5

1.99e-0441162GO:0099583
GeneOntologyMolecularFunctionsodium channel activity

SCN11A GRIA2 PKD2 CACNA1G

2.36e-04521164GO:0005272
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC37A3 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D SLC22A1 SLC5A12

3.16e-042931168GO:0008514
GeneOntologyMolecularFunctionamide binding

CACNA1B APBB2 GRIA1 GRIA2 GRIA3 GRIA4 SCARB1 DHFR2

3.61e-042991168GO:0033218
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

3.69e-041051165GO:0015171
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A PKD2 CACNA1G

4.51e-04261163GO:0005248
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1B SCN11A SLC37A3 TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D ATP5MG SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

4.62e-04118011617GO:0022857
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A GRIA2 SLC22A1 PKD2 CACNA1G SLC5A12

4.93e-041711166GO:0015081
GeneOntologyMolecularFunctionprotein kinase binding

TRIB2 PPM1D GRIA1 GRIA2 PTPN22 SPG11 CNTLN GRM5 NEK9 RIMS1 MAPK8 MAPK9 TRIB1 DNM2

5.41e-0487311614GO:0019901
GeneOntologyMolecularFunctionmannosyltransferase activity

ALG9 DPY19L4 ALG3

5.63e-04281163GO:0000030
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

RIMS1 RIMS2

9.16e-0481162GO:0098882
GeneOntologyMolecularFunctionadenosine receptor binding

GRM5 USP4

9.16e-0481162GO:0031685
GeneOntologyMolecularFunctiontransporter activity

CACNA1B SCN11A SLC37A3 TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 TMC4 GRIN2D ATP5MG SLC22A1 PKD2 CACNA1G SLC5A12 KCNT1

1.24e-03128911617GO:0005215
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D SLC5A12

1.33e-032071166GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D SLC5A12

1.36e-032081166GO:0005342
GeneOntologyMolecularFunctionhexosyltransferase activity

GBA2 STT3A ALG9 DPY19L4 ALG3 ALG6

1.47e-032111166GO:0016758
GeneOntologyMolecularFunctionkinase binding

TRIB2 PPM1D GRIA1 GRIA2 PTPN22 SPG11 CNTLN GRM5 NEK9 RIMS1 MAPK8 MAPK9 TRIB1 DNM2

1.48e-0396911614GO:0019900
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1B GRIN2D PKD2 CACNA1G KCNT1

1.95e-031521165GO:0022843
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1B PKD2 CACNA1G

2.42e-03461163GO:0005245
GeneOntologyMolecularFunctionprotein serine/threonine/tyrosine kinase activity

MAPK8 MAPK9 MAPK10

2.57e-03471163GO:0004712
GeneOntologyMolecularFunctionpeptide binding

CACNA1B APBB2 GRIA1 GRIA2 GRIA3 GRIA4 SCARB1

2.58e-033181167GO:0042277
GeneOntologyMolecularFunctionbeta-tubulin binding

BCAS3 ARL8A ARL8B

2.90e-03491163GO:0048487
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1B CACNA1G

2.91e-03141162GO:0008331
GeneOntologyMolecularFunctionenzyme regulator activity

EED TRIB2 FN1 SWAP70 BCAS3 STXBP5 LARS1 COX15 GRM5 NEK9 STK3 BTK RIMS1 MAPK8 MAPK9 CABIN1 TRIB1

3.37e-03141811617GO:0030234
GeneOntologyMolecularFunctionadenylate cyclase binding

AKAP6 GRIA1

3.81e-03161162GO:0008179
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1B GRIN2D PKD2 CACNA1G KCNT1

4.23e-031821165GO:0005244
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP6 USP8 JOSD1 USP4

4.42e-031141164GO:0004843
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1B GRIN2D PKD2 CACNA1G KCNT1

4.43e-031841165GO:0022832
GeneOntologyMolecularFunctionenzyme activator activity

EED FN1 BCAS3 STXBP5 LARS1 GRM5 NEK9 STK3 BTK MAPK9

4.92e-0365611610GO:0008047
GeneOntologyMolecularFunctionmitogen-activated protein kinase kinase binding

TRIB2 TRIB1

5.36e-03191162GO:0031434
GeneOntologyMolecularFunctiondeubiquitinase activity

USP6 USP8 JOSD1 USP4

5.94e-031241164GO:0101005
GeneOntologyMolecularFunctionglycosyltransferase activity

GBA2 STT3A ALG9 DPY19L4 ALG3 ALG6

6.76e-032881166GO:0016757
GeneOntologyMolecularFunctionglucosyltransferase activity

GBA2 ALG6

7.16e-03221162GO:0046527
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 DAGLA

3.52e-08591147GO:0007215
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

RELN GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 RIMS1 RIMS2 KCNT1

6.20e-0818011410GO:0060078
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

3.46e-07271145GO:0035235
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

CACNA1B RELN STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRIN2D ZDHHC17 GRM5 USP8 RIMS1 MAPK8 MAPK9 RIMS2

7.51e-0766311416GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

CACNA1B RELN STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRIN2D ZDHHC17 GRM5 USP8 RIMS1 MAPK8 MAPK9 RIMS2

7.66e-0766411416GO:0099177
GeneOntologyBiologicalProcessregulation of membrane potential

AKAP6 SCN11A RELN TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 CACNA1G RIMS1 RIMS2 KCNT1

2.55e-0655911414GO:0042391
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.66e-06401145GO:1990806
GeneOntologyBiologicalProcesstrans-synaptic signaling

CACNA1B RELN STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRIN2D ZDHHC17 GRM5 USP8 CACNA1G RIMS1 MAPK8 MAPK9 RIMS2 DAGLA

3.87e-0693911418GO:0099537
GeneOntologyBiologicalProcessmonoatomic ion transport

AKAP6 CACNA1B SCN11A RELN TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 PTPN22 SPG11 TMC4 GRIN2D ATP5MG SLC22A1 PKD2 FGF11 CACNA1G SLC5A12 KCNT1 DNM2

5.40e-06137411422GO:0006811
GeneOntologyBiologicalProcessregulation of calcium-dependent activation of synaptic vesicle fusion

CACNA1B RIMS1 RIMS2

5.66e-0671143GO:0150037
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission

CACNA1B RELN GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D RIMS1 RIMS2

5.95e-062331149GO:0050806
GeneOntologyBiologicalProcesssynaptic signaling

CACNA1B RELN STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRIN2D ZDHHC17 GRM5 USP8 CACNA1G RIMS1 MAPK8 MAPK9 RIMS2 DAGLA

6.60e-0697611418GO:0099536
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

RELN GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

8.73e-061321147GO:0035249
GeneOntologyBiologicalProcessFc-epsilon receptor signaling pathway

BTK MAPK8 MAPK9 MAPK10

1.02e-05251144GO:0038095
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

AKAP6 CACNA1B SCN11A RELN TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 PTPN22 TMC4 GRIN2D ATP5MG SLC22A1 PKD2 FGF11 CACNA1G KCNT1

1.10e-05111511419GO:0034220
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

CACNA1B RELN STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRIN2D ZDHHC17 GRM5 USP8 CACNA1G RIMS1 MAPK8 MAPK9 RIMS2

1.40e-0593111417GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

CACNA1B RELN STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRIN2D ZDHHC17 GRM5 USP8 CACNA1G RIMS1 MAPK8 MAPK9 RIMS2

1.40e-0593111417GO:0007268
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

GRIA1 GRIA3 GRIA4 GRIN2D

2.82e-05321144GO:0099505
GeneOntologyBiologicalProcessneuron projection morphogenesis

SCN11A RELN FN1 EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 LIFR HMCN2 MACF1 RIMS1 MAPK8 RIMS2 DNM2

3.57e-0580211415GO:0048812
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle fusion to presynaptic active zone membrane

CACNA1B RIMS1 RIMS2

4.52e-05131143GO:0031632
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle membrane organization

CACNA1B RIMS1 RIMS2

4.52e-05131143GO:1901634
GeneOntologyBiologicalProcesscalcium-dependent activation of synaptic vesicle fusion

CACNA1B RIMS1 RIMS2

4.52e-05131143GO:0099502
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

SCN11A RELN FN1 EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 LIFR HMCN2 MACF1 RIMS1 MAPK8 RIMS2 DNM2

4.53e-0581911415GO:0120039
GeneOntologyBiologicalProcessneuron development

SCN11A RELN FN1 TOX EPHA6 STXBP5 APBB2 SPG11 ZMIZ1 ZDHHC17 GBA2 LIFR HMCN2 DHFR2 MACF1 RIMS1 MAPK8 MAPK9 RIMS2 STK24 DNM2

4.66e-05146311421GO:0048666
GeneOntologyBiologicalProcesscell projection morphogenesis

SCN11A RELN FN1 EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 LIFR HMCN2 MACF1 RIMS1 MAPK8 RIMS2 DNM2

4.99e-0582611415GO:0048858
GeneOntologyBiologicalProcessaxon development

SCN11A RELN FN1 EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 HMCN2 DHFR2 MACF1 STK24 DNM2

5.53e-0564211413GO:0061564
GeneOntologyBiologicalProcessneuron projection development

SCN11A RELN FN1 TOX EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 LIFR HMCN2 DHFR2 MACF1 RIMS1 MAPK8 MAPK9 RIMS2 STK24 DNM2

7.64e-05128511419GO:0031175
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

RELN GRIN2D RIMS1 RIMS2

9.25e-05431144GO:2000463
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

RELN GRIA2 GRIA4 GRIN2D GRM5

1.58e-04921145GO:0051966
GeneOntologyBiologicalProcessregulation of synaptic vesicle fusion to presynaptic active zone membrane

CACNA1B RIMS1 RIMS2

1.75e-04201143GO:0031630
GeneOntologyBiologicalProcessregulation of synaptic vesicle membrane organization

CACNA1B RIMS1 RIMS2

1.75e-04201143GO:1901632
GeneOntologyBiologicalProcesspositive regulation of vesicle fusion

CACNA1B RIMS1 RIMS2

1.75e-04201143GO:0031340
GeneOntologyBiologicalProcessprotein localization to tricellular tight junction

MAPK8 MAPK9

1.80e-0441142GO:0061833
GeneOntologyBiologicalProcesspositive regulation of protein modification by small protein conjugation or removal

TRIB2 PTPN22 DCUN1D1 MAPK8 MAPK9 TRIB1

1.87e-041501146GO:1903322
GeneOntologyBiologicalProcesspositive regulation of post-translational protein modification

TRIB2 PTPN22 DCUN1D1 MAPK8 MAPK9 TRIB1

1.94e-041511146GO:1901875
GeneOntologyBiologicalProcessmonoatomic cation transport

AKAP6 CACNA1B SCN11A TRPC4 COX15 GRIA2 PTPN22 SPG11 GRIN2D ATP5MG SLC22A1 PKD2 FGF11 CACNA1G SLC5A12 KCNT1 DNM2

2.05e-04115711417GO:0006812
GeneOntologyBiologicalProcessregulated exocytosis

CACNA1B SCN11A STXBP5 ARL8B BTK CACNA1G RIMS1 RIMS2

2.16e-042911148GO:0045055
GeneOntologyBiologicalProcessregulation of synaptic plasticity

RELN GRIA1 GRIA3 SPG11 GRIN2D GRM5 RIMS1 RIMS2

2.26e-042931148GO:0048167
GeneOntologyBiologicalProcessdolichol-linked oligosaccharide biosynthetic process

ALG9 ALG3 ALG6

2.35e-04221143GO:0006488
GeneOntologyBiologicalProcessregulation of protein ubiquitination

TRIB2 PTPN22 DCUN1D1 USP4 MAPK8 MAPK9 TRIB1

2.63e-042261147GO:0031396
GeneOntologyBiologicalProcesspositive regulation of NLRP3 inflammasome complex assembly

PTPN22 BTK MAPK8

2.69e-04231143GO:1900227
GeneOntologyBiologicalProcessaxonogenesis

SCN11A RELN FN1 EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 HMCN2 MACF1 DNM2

3.03e-0456611411GO:0007409
GeneOntologyBiologicalProcesscentrosome cycle

CDK11A CNTLN NEK2 PKD2 MAPK8 DNM2

3.03e-041641146GO:0007098
GeneOntologyBiologicalProcessdolichol metabolic process

ALG9 ALG3 ALG6

3.06e-04241143GO:0019348
GeneOntologyBiologicalProcessexocytic process

CACNA1B STXBP5 BTK RIMS1 RIMS2

3.21e-041071145GO:0140029
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

AKAP6 MRC1 NUGGC ERN1 LARS1 GRIA1 GRIA2 PTPN22 GRIN2D GRM5 USP8 SCARB1 BTK DHFR2 PKD2 MAPK8 MAPK9 TRIB1 DNM2

3.62e-04145011419GO:1901701
GeneOntologyBiologicalProcessFc receptor signaling pathway

BTK MAPK8 MAPK9 MAPK10

3.86e-04621144GO:0038093
GeneOntologyBiologicalProcesspositive regulation of inflammasome-mediated signaling pathway

PTPN22 BTK MAPK8

3.90e-04261143GO:0141087
GeneOntologyBiologicalProcessnegative regulation of interleukin-10 production

TRIB2 BTK IL23R

3.90e-04261143GO:0032693
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

RELN GRIN2D RIMS1 RIMS2

4.62e-04651144GO:0098815
GeneOntologyBiologicalProcesscellular response to reactive oxygen species

ERN1 BTK DHFR2 PKD2 MAPK8 MAPK9

4.69e-041781146GO:0034614
GeneOntologyBiologicalProcessmicrotubule organizing center organization

CDK11A CNTLN NEK2 PKD2 MAPK8 DNM2

4.83e-041791146GO:0031023
GeneOntologyBiologicalProcesspolyprenol metabolic process

ALG9 ALG3 ALG6

5.41e-04291143GO:0016093
GeneOntologyBiologicalProcesspositive regulation of proteasomal protein catabolic process

TRIB2 ERN1 MAPK8 MAPK9 TRIB1

6.08e-041231145GO:1901800
GeneOntologyBiologicalProcesspositive regulation of protein ubiquitination

TRIB2 PTPN22 MAPK8 MAPK9 TRIB1

6.30e-041241145GO:0031398
GeneOntologyBiologicalProcesssynaptic vesicle fusion to presynaptic active zone membrane

CACNA1B RIMS1 RIMS2

6.60e-04311143GO:0031629
GeneOntologyBiologicalProcessregulation of receptor recycling

GRIA1 GRIA2 GRIA3

6.60e-04311143GO:0001919
GeneOntologyBiologicalProcesssynaptic vesicle priming

STXBP5 RIMS1 RIMS2

6.60e-04311143GO:0016082
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

AKAP6 CACNA1B SCN11A TRPC4 COX15 GRIA2 PTPN22 GRIN2D ATP5MG SLC22A1 PKD2 FGF11 CACNA1G KCNT1

6.97e-0494211414GO:0098655
GeneOntologyBiologicalProcesscalcium-mediated signaling

AKAP6 GRIA1 GRIA3 GRIN2D GRM5 BTK PKD2

6.98e-042661147GO:0019722
GeneOntologyBiologicalProcessvesicle fusion to plasma membrane

CACNA1B RIMS1 RIMS2

7.26e-04321143GO:0099500
GeneOntologyBiologicalProcessregulation of protein modification by small protein conjugation or removal

TRIB2 PTPN22 DCUN1D1 USP4 MAPK8 MAPK9 TRIB1

7.79e-042711147GO:1903320
GeneOntologyBiologicalProcessdetection of mechanical stimulus

MKKS SCN11A GRIN2D PKD2

7.95e-04751144GO:0050982
GeneOntologyBiologicalProcessJNK cascade

PTPN22 STK3 MAPK8 MAPK9 MAPK10 TRIB1

8.19e-041981146GO:0007254
GeneOntologyBiologicalProcessprotein N-linked glycosylation

STT3A ALG9 ALG3 ALG6

8.36e-04761144GO:0006487
GeneOntologyBiologicalProcessregulation of post-translational protein modification

TRIB2 PTPN22 DCUN1D1 USP4 MAPK8 MAPK9 TRIB1

8.85e-042771147GO:1901873
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SCN11A RELN FN1 EPHA6 STXBP5 APBB2 SPG11 ZDHHC17 HMCN2 MACF1 MAPK8 DNM2

8.89e-0474811412GO:0048667
GeneOntologyBiologicalProcesspositive regulation of TOR signaling

RELN LARS1 USP6 USP4

9.22e-04781144GO:0032008
GeneOntologyBiologicalProcessregulation of vesicle fusion

CACNA1B RIMS1 RIMS2

9.46e-04351143GO:0031338
GeneOntologyBiologicalProcesspositive regulation of pattern recognition receptor signaling pathway

DHX58 PTPN22 BTK MAPK8

9.67e-04791144GO:0062208
GeneOntologyBiologicalProcesssynaptic vesicle membrane organization

CACNA1B RIMS1 RIMS2

1.03e-03361143GO:0048499
GeneOntologyBiologicalProcessneuron projection extension

FN1 SPG11 MACF1 RIMS1 RIMS2 DNM2

1.03e-032071146GO:1990138
GeneOntologyBiologicalProcessglycoside catabolic process

GBA2 FUCA2

1.06e-0391142GO:0016139
GeneOntologyBiologicalProcesscalcium-ion regulated exocytosis

ARL8B CACNA1G RIMS1 RIMS2

1.11e-03821144GO:0017156
GeneOntologyBiologicalProcessvesicle fusion

CACNA1B SPG11 ARL8B RIMS1 RIMS2

1.16e-031421145GO:0006906
GeneOntologyBiologicalProcessregulation of microtubule-based process

MKKS RSPH4A CDK11A GBA2 PHLDB1 MACF1 MAPK8

1.23e-032931147GO:0032886
GeneOntologyBiologicalProcesslong-term synaptic potentiation

RELN GRIA1 GRIA3 GRIN2D RIMS1

1.23e-031441145GO:0060291
GeneOntologyBiologicalProcessorganelle membrane fusion

CACNA1B SPG11 ARL8B RIMS1 RIMS2

1.23e-031441145GO:0090174
GeneOntologyBiologicalProcesspositive regulation of proteasomal ubiquitin-dependent protein catabolic process

TRIB2 MAPK8 MAPK9 TRIB1

1.27e-03851144GO:0032436
GeneOntologyBiologicalProcesscellular response to oxidative stress

ERN1 BTK DHFR2 PKD2 MAPK8 MAPK9 STK24

1.27e-032951147GO:0034599
GeneOntologyBiologicalProcessheme A biosynthetic process

HMBS COX15

1.32e-03101142GO:0006784
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

RIMS1 RIMS2

1.32e-03101142GO:0097151
GeneOntologyBiologicalProcessheme a metabolic process

HMBS COX15

1.32e-03101142GO:0046160
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

CACNA1B RELN FN1 TOX SWAP70 PTPN22 USP8 NEK2 PHLDB1 BTK MACF1 RIMS1 MAPK8 MAPK9 RIMS2 STK24 DNM2

1.34e-03136611417GO:0051130
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

RELN GRIA4 GRIN2D RIMS1 RIMS2

1.35e-031471145GO:0099565
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

AKAP6 CACNA1B RELN TRPC4 PTPN22 SPG11 GRIN2D PKD2 FGF11 CACNA1G

1.37e-0357711410GO:0043269
GeneOntologyBiologicalProcesspositive regulation of proteolysis involved in protein catabolic process

TRIB2 ERN1 MAPK8 MAPK9 TRIB1

1.39e-031481145GO:1903052
GeneOntologyBiologicalProcessdevelopmental cell growth

AKAP6 FN1 SPG11 MACF1 RIMS1 RIMS2 DNM2

1.43e-033011147GO:0048588
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

AKAP6 CACNA1B SCN11A TRPC4 PTPN22 GRIN2D PKD2 CACNA1G

1.51e-033921148GO:0070588
GeneOntologyCellularComponentmonoatomic ion channel complex

AKAP6 CACNA1B SCN11A STXBP5 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ATP5MG PKD2 CACNA1G

1.67e-0737811513GO:0034702
GeneOntologyCellularComponentneuron to neuron synapse

STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 USP6 USP8 MACF1 RIMS1 MAPK10 DAGLA KCNT1 DNM2

1.86e-0752311515GO:0098984
GeneOntologyCellularComponentpostsynaptic density

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 USP6 USP8 MACF1 RIMS1 MAPK10 DAGLA KCNT1 DNM2

1.89e-0745111514GO:0014069
GeneOntologyCellularComponentasymmetric synapse

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 USP6 USP8 MACF1 RIMS1 MAPK10 DAGLA KCNT1 DNM2

3.73e-0747711514GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 USP6 USP8 MACF1 RIMS1 MAPK10 DAGLA KCNT1 DNM2

7.03e-0750311514GO:0099572
GeneOntologyCellularComponentpresynaptic active zone

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D RIMS1 RIMS2

1.13e-061411158GO:0048786
GeneOntologyCellularComponentpostsynaptic density membrane

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 DAGLA KCNT1

2.54e-061571158GO:0098839
GeneOntologyCellularComponentpresynaptic membrane

SCN11A STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ZDHHC17 RIMS1 RIMS2

3.11e-0627711510GO:0042734
GeneOntologyCellularComponentsynaptic membrane

SCN11A STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ZDHHC17 GRM5 RIMS1 RIMS2 DAGLA KCNT1 DNM2

3.95e-0658311514GO:0097060
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D RIMS1

4.52e-06781156GO:0048787
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

4.73e-06451155GO:0008328
GeneOntologyCellularComponenttransmembrane transporter complex

AKAP6 CACNA1B SCN11A STXBP5 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ATP5MG PKD2 CACNA1G

6.19e-0652311513GO:1902495
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

8.03e-06501155GO:0098878
GeneOntologyCellularComponenttransporter complex

AKAP6 CACNA1B SCN11A STXBP5 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ATP5MG PKD2 CACNA1G

1.06e-0555011513GO:1990351
GeneOntologyCellularComponentpostsynaptic specialization membrane

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 DAGLA KCNT1

1.56e-052011158GO:0099634
GeneOntologyCellularComponentAMPA glutamate receptor complex

GRIA1 GRIA2 GRIA3 GRIA4

2.13e-05301154GO:0032281
GeneOntologyCellularComponentaxon

CACNA1B SCN11A RELN APBB2 HMBS GRIA1 GRIA2 GRIA3 GRIA4 SPG11 ARL8A HMCN2 ARL8B MAPK8 DAGLA DNM2

2.98e-0589111516GO:0030424
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

ALG9 PKD2 ALG3 ALG6

3.99e-05351154GO:0098553
GeneOntologyCellularComponentglutamatergic synapse

CACNA1B SCN11A GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ZDHHC17 GRM5 USP6 USP8 RIMS1 MAPK10 RIMS2 DNM2

4.20e-0581711515GO:0098978
GeneOntologyCellularComponentcation channel complex

AKAP6 CACNA1B SCN11A TRPC4 GRIA4 ATP5MG PKD2 CACNA1G

4.77e-052351158GO:0034703
GeneOntologyCellularComponentdendritic shaft

CACNA1B GRIA1 GRIA2 GRIA3 GRM5

5.50e-05741155GO:0043198
GeneOntologyCellularComponentpostsynaptic Golgi apparatus

ZDHHC17 MAPK10

8.97e-0531152GO:0150051
GeneOntologyCellularComponentcell cortex region

PHLDB1 PKD2 RIMS1 RIMS2

1.09e-04451154GO:0099738
GeneOntologyCellularComponentlumenal side of membrane

ALG9 PKD2 ALG3 ALG6

1.40e-04481154GO:0098576
GeneOntologyCellularComponentpostsynapse

SWAP70 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ZDHHC17 GRM5 USP6 USP8 MACF1 RIMS1 MAPK10 DAGLA KCNT1 DNM2

1.43e-04101811516GO:0098794
GeneOntologyCellularComponentcytoplasmic region

RSPH4A GRIA2 ARL8A PHLDB1 ARL8B PKD2 RIMS1 MAPK8 RIMS2

1.71e-043601159GO:0099568
GeneOntologyCellularComponentperisynaptic space

GRIA1 GRIA2

1.79e-0441152GO:0099544
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

CACNA1B STXBP5 GRIA2 GRM5 MAPK8 MAPK9

2.18e-041551156GO:0098685
GeneOntologyCellularComponentdendritic spine

GRIA1 GRIA2 GRIA3 GRIA4 GRM5 USP8 DAGLA

3.88e-042421157GO:0043197
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1B SCN11A RELN EPHA6 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRM5 USP8 HMCN2 CACNA1G MAPK8 MAPK9 MAPK10 DAGLA

3.91e-04122811517GO:0036477
GeneOntologyCellularComponentpostsynaptic membrane

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 DAGLA KCNT1 DNM2

4.06e-044051159GO:0045211
GeneOntologyCellularComponentneuron spine

GRIA1 GRIA2 GRIA3 GRIA4 GRM5 USP8 DAGLA

4.38e-042471157GO:0044309
GeneOntologyCellularComponentcell leading edge

SWAP70 BCAS3 APBB2 GRIA1 GRIA2 FAP PKD2 MACF1 DAGLA DNM2

4.44e-0450011510GO:0031252
GeneOntologyCellularComponentmembrane protein complex

AKAP6 CACNA1B SCN11A ERN1 STXBP5 TRPC4 GRIA1 COX15 GRIA2 GRIA3 GRIA4 GRIN2D STT3A ATP5MG CYCS PKD2 CACNA1G EMC2 IL23R

5.14e-04149811519GO:0098796
GeneOntologyCellularComponentsodium channel complex

SCN11A GRIA4 CACNA1G

5.34e-04291153GO:0034706
GeneOntologyCellularComponentbasal cortex

PHLDB1 PKD2

6.19e-0471152GO:0045180
GeneOntologyCellularComponentcalcium channel complex

AKAP6 CACNA1B TRPC4 CACNA1G

7.06e-04731154GO:0034704
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

RIMS1 RIMS2

8.22e-0481152GO:0048788
GeneOntologyCellularComponentdendrite

CACNA1B RELN EPHA6 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRM5 USP8 CACNA1G MAPK8 DAGLA

8.79e-0485811513GO:0030425
GeneOntologyCellularComponentdendritic tree

CACNA1B RELN EPHA6 GRIA1 GRIA2 GRIA3 GRIA4 SPG11 GRM5 USP8 CACNA1G MAPK8 DAGLA

8.98e-0486011513GO:0097447
GeneOntologyCellularComponentleading edge membrane

GRIA1 GRIA2 FAP MACF1 DAGLA DNM2

1.09e-032101156GO:0031256
GeneOntologyCellularComponentendocytic vesicle membrane

GRIA1 GRIA2 GRIA3 GRIA4 SCARB1 DNM2

1.14e-032121156GO:0030666
GeneOntologyCellularComponentpresynapse

CACNA1B SCN11A STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D ZDHHC17 SLC22A1 RIMS1 RIMS2 DNM2

1.18e-0388611513GO:0098793
GeneOntologyCellularComponentperikaryon

RELN GRIA2 GRIA3 MAPK8 MAPK9 MAPK10

1.48e-032231156GO:0043204
GeneOntologyCellularComponentneuronal cell body

CACNA1B SCN11A RELN GRIA1 GRIA2 GRIA3 GRIA4 HMCN2 CACNA1G MAPK8 MAPK9 MAPK10

2.17e-0383511512GO:0043025
GeneOntologyCellularComponentpostsynaptic density, intracellular component

GRIA1 USP6 DNM2

2.49e-03491153GO:0099092
GeneOntologyCellularComponentpresynaptic cytoskeleton

RIMS1 RIMS2

2.61e-03141152GO:0099569
GeneOntologyCellularComponentcell projection membrane

GRIA1 GRIA2 FAP SCARB1 PKD2 MACF1 DAGLA DNM2

2.65e-034311158GO:0031253
GeneOntologyCellularComponentneuron projection cytoplasm

GRIA2 ARL8A ARL8B MAPK8

3.21e-031101154GO:0120111
GeneOntologyCellularComponentplasma membrane signaling receptor complex

STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D IL23R

3.25e-033501157GO:0098802
GeneOntologyCellularComponentdendrite membrane

GRIA1 GRIA2 DAGLA

3.64e-03561153GO:0032590
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

GRIA1 USP6 DNM2

3.64e-03561153GO:0099091
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A CACNA1G

3.87e-03171152GO:0001518
GeneOntologyCellularComponentdendritic spine membrane

GRIA1 DAGLA

4.33e-03181152GO:0032591
GeneOntologyCellularComponentextrinsic component of presynaptic membrane

STXBP5 RIMS1

4.33e-03181152GO:0098888
GeneOntologyCellularComponentcell cortex

TRPC4 PHLDB1 HMCN2 PKD2 MACF1 RIMS1 RIMS2

4.47e-033711157GO:0005938
GeneOntologyCellularComponentlysosome

SLC37A3 LARS1 SPG11 ARL8A CHIT1 USP6 ARSD ARL8B SCARB1 USP4 FUCA2

5.11e-0381111511GO:0005764
GeneOntologyCellularComponentlytic vacuole

SLC37A3 LARS1 SPG11 ARL8A CHIT1 USP6 ARSD ARL8B SCARB1 USP4 FUCA2

5.11e-0381111511GO:0000323
GeneOntologyCellularComponentcell body

CACNA1B SCN11A RELN GRIA1 GRIA2 GRIA3 GRIA4 HMCN2 CACNA1G MAPK8 MAPK9 MAPK10

5.12e-0392911512GO:0044297
GeneOntologyCellularComponentcytoplasmic vesicle membrane

MRC1 STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 ARL8A ZDHHC17 LRIG3 USP8 ARL8B SCARB1 PKD2 DAGLA DNM2

5.34e-03130711515GO:0030659
GeneOntologyCellularComponentvesicle membrane

MRC1 STXBP5 GRIA1 GRIA2 GRIA3 GRIA4 ARL8A ZDHHC17 LRIG3 USP8 ARL8B SCARB1 PKD2 DAGLA DNM2

6.05e-03132511515GO:0012506
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

RIMS1 RIMS2

7.04e-03231152GO:0098831
GeneOntologyCellularComponentmidbody

ARL8A USP8 NEK2 ARL8B DNM2

7.71e-032221155GO:0030496
GeneOntologyCellularComponentlamellipodium

SWAP70 APBB2 FAP PKD2 DNM2

8.91e-032301155GO:0030027
MousePhenoabnormal single cell response

CACNA1B SCN11A TRPC4 CACNA1G DAGLA

3.60e-0635955MP:0003463
MousePhenoabnormal excitatory postsynaptic potential

CACNA1B TRIB2 STXBP5 GRIA2 GRIA4 GRM5 MAPK9

5.85e-06102957MP:0002912
MousePhenoabnormal synaptic transmission

CACNA1B SCN11A RELN TRIB2 DHX58 TOX STXBP5 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 ZDHHC17 GRM5 ARL8B DHFR2 CACNA1G MAPK9 DAGLA KCNT1

2.70e-0510709520MP:0003635
MousePhenoabnormal CNS synaptic transmission

CACNA1B SCN11A RELN TRIB2 DHX58 TOX STXBP5 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 ZDHHC17 GRM5 ARL8B DHFR2 MAPK9 DAGLA KCNT1

2.90e-059859519MP:0002206
MousePhenoabnormal synaptic physiology

CACNA1B SCN11A RELN TRIB2 DHX58 TOX STXBP5 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 ZDHHC17 GRM5 ARL8B DHFR2 CACNA1G MAPK9 DAGLA KCNT1

2.93e-0510769520MP:0021009
MousePhenodecreased susceptibility to induction of seizure by inducing agent

GRIA3 GRM5 CACNA1G MAPK10

4.17e-0529954MP:0012348
MousePhenodecreased susceptibility to pharmacologically induced seizures

GRIA3 GRM5 CACNA1G MAPK10

4.17e-0529954MP:0002887
MousePhenoabnormal gait

CACNA1B RELN STXBP5 HMBS GRIA1 SPG11 NEB CMAS STK3 ATP5MG LRIG3 CACNA1G DNM2

4.81e-055209513MP:0001406
MousePhenoabnormal channel response

CACNA1B SCN11A CACNA1G KCNT1

7.04e-0533954MP:0003484
MousePhenoabnormal nervous system electrophysiology

CACNA1B SCN11A TRPC4 GRIA2 GRIA4 GRM5 CACNA1G DAGLA KCNT1 DNM2

7.82e-053299510MP:0002272
MousePhenoimpaired ability to fire action potentials

GRIA4 CACNA1G KCNT1

8.28e-0513953MP:0002578
MousePhenoabnormal skin morphology

NUGGC SCN11A FRAS1 RELN FN1 EPHA6 ERN1 PPM1D APBB2 CDK11A ZMIZ1 NEK9 PHKA1 LRIG3 XIRP2 DHFR2 CACNA1G MAPK8 MAPK9 ALG6 WDR49 TRIB1 ACOXL

8.51e-0514559523MP:0002060
MousePhenoabnormal locomotor coordination

CACNA1B RELN STXBP5 HMBS GRIA1 SPG11 ZDHHC17 NEB CMAS STK3 ATP5MG LRIG3 CYCS CACNA1G DNM2

1.06e-047269515MP:0003312
MousePhenoabnormal long-term potentiation

CACNA1B TRIB2 STXBP5 GRIA1 GRIA2 GRIA3 GRM5 MAPK9

1.28e-04221958MP:0002207
MousePhenodecreased alcohol consumption

CACNA1B GRIA3 GRM5

1.60e-0416953MP:0003546
MousePhenodecreased fluid intake

CACNA1B TRIB2 GRIA3 GRM5

1.67e-0441954MP:0011942
MousePhenoabnormal nociception after inflammation

SCN11A GRIA1 GRIA2 GRM5

2.21e-0444954MP:0002736
MousePhenoabnormal touch/ nociception

CACNA1B SCN11A GRIA1 GRIA2 GRIA3 GRIA4 GRM5 FGF11 TRIB1 KCNT1

2.33e-043769510MP:0001968
DomainKinase-like_dom

TRIB2 EPHA6 ERN1 CDK11A ALPK1 NEK9 PRKD3 STK3 NEK2 BTK MACF1 MAPK8 MAPK9 MAPK10 STK24 TRIB1 DNM2

3.59e-0854211517IPR011009
DomainLig_chan-Glu_bd

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155PF10613
DomainGlu/Gly-bd

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155IPR019594
DomainLig_chan-Glu_bd

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155SM00918
DomainIontro_rcpt

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155IPR001320
DomainIono_rcpt_met

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155IPR001508
DomainLig_chan

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155PF00060
DomainPBPe

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

6.52e-08181155SM00079
DomainANF_lig-bd_rcpt

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

9.51e-08371156IPR001828
DomainANF_receptor

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

9.51e-08371156PF01094
DomainPeripla_BP_I

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.32e-07391156IPR028082
DomainProt_kinase_dom

TRIB2 EPHA6 ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24 TRIB1

1.88e-0648911514IPR000719
DomainPROTEIN_KINASE_DOM

TRIB2 EPHA6 ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24 TRIB1

2.06e-0649311514PS50011
DomainMAPK_JNK

MAPK8 MAPK9 MAPK10

2.25e-0651153IPR008351
DomainPkinase

TRIB2 ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 MAPK8 MAPK9 MAPK10 STK24 TRIB1

4.08e-0638111512PF00069
DomainS_TKc

ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 MAPK8 MAPK9 MAPK10 STK24 TRIB1

1.36e-0535911511SM00220
DomainPROTEIN_KINASE_ATP

EPHA6 ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 BTK MAPK8 MAPK9 MAPK10 STK24

2.63e-0545911512PS00107
DomainMAGEA3/MAGEA6

MAGEA3 MAGEA6

3.76e-0521152IPR030097
DomainMAPK

MAPK8 MAPK9 MAPK10

4.80e-05121153PS01351
DomainMAP_kinase_CS

MAPK8 MAPK9 MAPK10

4.80e-05121153IPR003527
DomainSer/Thr_kinase_AS

ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 MAPK8 MAPK9 MAPK10 STK24

7.23e-0535711510IPR008271
DomainPROTEIN_KINASE_ST

ERN1 CDK11A NEK9 PRKD3 STK3 NEK2 MAPK8 MAPK9 MAPK10 STK24

8.11e-0536211510PS00108
DomainTribbles/Ser_Thr_kinase_40

TRIB2 TRIB1

2.24e-0441152IPR024104
DomainMAGE_N

MAGEA3 MAGEA6 MAGEA9

2.40e-04201153SM01392
DomainMAGE_N

MAGEA3 MAGEA6 MAGEA9

3.22e-04221153PF12440
DomainMAGE_N

MAGEA3 MAGEA6 MAGEA9

3.22e-04221153IPR021072
DomainChannel_four-helix_dom

CACNA1B SCN11A PKD2 CACNA1G

4.19e-04571154IPR027359
Domain-

CACNA1B SCN11A PKD2 CACNA1G

4.19e-045711541.20.120.350
DomainMAGE

MAGEA3 MAGEA6 MAGEA9

1.18e-03341153SM01373
DomainMAGE

MAGEA3 MAGEA6 MAGEA9

1.40e-03361153PS50838
DomainMHD_dom

MAGEA3 MAGEA6 MAGEA9

1.40e-03361153IPR002190
DomainMAGE

MAGEA3 MAGEA6 MAGEA9

1.40e-03361153PF01454
DomainVDCCAlpha1

CACNA1B CACNA1G

1.64e-03101152IPR002077
DomainFYVE_2

RIMS1 RIMS2

1.99e-03111152PF02318
DomainRABBD

RIMS1 RIMS2

2.38e-03121152PS50916
DomainRab_BD

RIMS1 RIMS2

2.38e-03121152IPR010911
Domain6-hairpin_glycosidase-like

GBA2 PHKA1

2.80e-03131152IPR008928
Domain-

MRC1 FN1

2.80e-031311522.10.10.10
DomainFN_type2_col-bd

MRC1 FN1

3.26e-03141152IPR000562
DomainFN2_2

MRC1 FN1

3.26e-03141152PS51092
DomainFN2_1

MRC1 FN1

3.26e-03141152PS00023
Domainfn2

MRC1 FN1

3.26e-03141152PF00040
DomainFN2

MRC1 FN1

3.26e-03141152SM00059
DomainDynamin_GTPase

NUGGC DNM2

3.74e-03151152IPR001401
DomainDynamin_SF

NUGGC DNM2

3.74e-03151152IPR022812
DomainDynamin_N

NUGGC DNM2

3.74e-03151152PF00350
DomainIon_trans_dom

CACNA1B SCN11A TRPC4 CACNA1G

5.41e-031141154IPR005821
DomainIon_trans

CACNA1B SCN11A TRPC4 CACNA1G

5.41e-031141154PF00520
PathwayKEGG_MEDICUS_REFERENCE_IRE1A_JNK_SIGNALING_PATHWAY

ERN1 MAPK8 MAPK9 MAPK10

5.12e-087894M47697
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

7.19e-0818895M48098
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

1.68e-0721895M838
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.17e-0722895MM15104
PathwayKEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

2.41e-065893M47570
PathwayKEGG_MEDICUS_ENV_FACTOR_PARAQUAT_TO_FAS_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

2.41e-065893M49021
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

2.41e-065893M49005
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.50e-0635895MM15109
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 GRIA4

2.55e-0616894MM15048
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 GRIA4

3.32e-0617894M5488
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

4.80e-066893M47680
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

4.80e-066893M47698
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY

MAPK8 MAPK9 MAPK10

4.80e-066893M47712
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

GRIA1 GRIA2 GRIA3 GRIA4 GRM5

5.61e-0641895M39655
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA1 GRIA3 GRIA4 GRIN2D

6.66e-0620894MM15485
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA1 GRIA3 GRIA4 GRIN2D

8.18e-0621894M27736
PathwayKEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

8.36e-067893M47711
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

GRIA1 GRIA2 GRIA3 GRIA4

9.95e-0622894M39795
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1B CACNA1G MAPK8 MAPK9 MAPK10

1.11e-0547895M19708
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

1.33e-058893M47814
PathwayWP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING

FN1 MAPK8 MAPK9 MAPK10

2.71e-0528894M39572
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK8 MAPK9 MAPK10

2.83e-0510893MM15135
PathwayREACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS

MAPK8 MAPK9 MAPK10

2.83e-0510893M13962
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

PSAT1 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.87e-05140897M42572
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 GRIA4

3.12e-0529894MM15028
PathwayWP_CANNABINOID_RECEPTOR_SIGNALING

MAPK8 MAPK9 MAPK10 DAGLA

3.12e-0529894M39676
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

GRIA1 GRIA2 GRIA3 GRIA4

4.10e-0531894M7223
PathwayKEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

5.14e-0512893M47929
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D SLC22A1 RIMS1

5.51e-05211898MM14502
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

GRIA1 GRIA3 GRIA4 GRIN2D GRM5

6.36e-0567895MM15327
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

6.65e-0513893M47594
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

EED MAPK8 MAPK9 MAPK10

8.36e-0537894MM14899
PathwayPID_FAS_PATHWAY

BTK MAPK8 MAPK9 MAPK10

9.30e-0538894M94
PathwayREACTOME_CELLULAR_SENESCENCE

EED ANAPC1 MAPK8 MAPK9 MAPK10 CABIN1

1.05e-04119896MM14901
PathwayKEGG_MEDICUS_REFERENCE_TNF_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

1.28e-0416893M47569
PathwayPID_ERBB2_ERBB3_PATHWAY

USP8 MAPK8 MAPK9 MAPK10

1.66e-0444894M175
PathwayKEGG_N_GLYCAN_BIOSYNTHESIS

STT3A ALG9 ALG3 ALG6

1.98e-0446894M11079
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

STK3 MAPK8 MAPK9 MAPK10

2.15e-0447894M39829
PathwayKEGG_MEDICUS_REFERENCE_IL1_IL1R_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

2.19e-0419893M47471
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

GRIA1 GRIA3 GRIA4 GRIN2D GRM5

2.20e-0487895M27617
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_N_GLYCOSYLATION_OF_PROTEINS

ALG9 ALG3 ALG6

2.57e-0420893M27274
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP

MAPK8 MAPK9 MAPK10

2.57e-0420893M47928
PathwayREACTOME_NEURONAL_SYSTEM

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 SLC22A1 RIMS1

2.60e-04335899MM14503
PathwayWP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING

GRIA1 GRIA2 GRIA3 MAPK8 MAPK9 MAPK10

2.96e-04144896M39691
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D SLC22A1 RIMS1

3.02e-04270898M15514
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

3.16e-0494895M2843
PathwayKEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS

GRIA1 GRIA2 GRIN2D CYCS

3.43e-0453894M3812
PathwayREACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1

MAPK8 MAPK9 MAPK10

3.43e-0422893M859
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1B CYCS CACNA1G

3.93e-0423893M47666
PathwayREACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1

MAPK8 MAPK9 MAPK10

3.93e-0423893MM15134
PathwayREACTOME_LONG_TERM_POTENTIATION

GRIA1 GRIA2 GRIN2D

3.93e-0423893M27949
PathwayWP_NGLYCAN_BIOSYNTHESIS

STT3A ALG9 ALG3 ALG6

4.54e-0457894M48051
PathwayWP_GLYCOSYLATION_AND_RELATED_CONGENITAL_DEFECTS

ALG9 ALG3 ALG6

5.06e-0425893M39813
PathwayWP_NOVEL_INTRACELLULAR_COMPONENTS_OF_RIGILIKE_RECEPTOR_PATHWAY

DHX58 MAPK8 MAPK9 MAPK10

5.53e-0460894M39583
PathwayKEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

5.69e-0426893M47565
PathwayKEGG_COLORECTAL_CANCER

CYCS MAPK8 MAPK9 MAPK10

6.26e-0462894M14631
PathwayREACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES

MAPK8 MAPK9 MAPK10

7.11e-0428893MM15132
PathwayREACTOME_TOLL_LIKE_RECEPTOR_CASCADES

ALPK1 BTK MAPK8 MAPK9 MAPK10 DNM2

7.16e-04170896M7494
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY

MAPK8 MAPK9 MAPK10

7.89e-0429893M47466
PathwayREACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE

ALPK1 BTK MAPK8 MAPK9 MAPK10

7.97e-04115895M27013
PathwayPID_P75_NTR_PATHWAY

CYCS MAPK8 MAPK9 MAPK10

8.88e-0468894M153
PathwayWP_MAPK_SIGNALING

CACNA1B STK3 FGF11 CACNA1G MAPK8 MAPK9 MAPK10

9.24e-04246897M39597
PathwayWP_UROTENSINIIMEDIATED_SIGNALING

FN1 TRPC4 MAPK8 MAPK9

9.39e-0469894M48052
PathwayREACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES

MAPK8 MAPK9 MAPK10

9.62e-0431893M15195
PathwayPID_NEPHRIN_NEPH1_PATHWAY

MAPK8 MAPK9 MAPK10

9.62e-0431893M193
PathwayPID_CD40_PATHWAY

MAPK8 MAPK9 MAPK10

9.62e-0431893M45
PathwayKEGG_LONG_TERM_DEPRESSION

GRIA1 GRIA2 GRIA3 GRM5

9.91e-0470894M8232
PathwayKEGG_LONG_TERM_POTENTIATION

GRIA1 GRIA2 GRIN2D GRM5

9.91e-0470894M3115
PathwayREACTOME_TOLL_LIKE_RECEPTOR_4_TLR4_CASCADE

ALPK1 MAPK8 MAPK9 MAPK10 DNM2

1.04e-03122895MM14640
PathwayKEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY

DHX58 MAPK8 MAPK9 MAPK10

1.04e-0371894M15913
PathwayPID_WNT_NONCANONICAL_PATHWAY

MAPK8 MAPK9 MAPK10

1.06e-0332893M23
PathwayREACTOME_NEURONAL_SYSTEM

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 SLC22A1 RIMS1

1.13e-03411899M735
PathwayPID_NCADHERIN_PATHWAY

GRIA2 MAPK8 DAGLA

1.16e-0333893M266
PathwayWP_CHROMOSOMAL_AND_MICROSATELLITE_INSTABILITY_IN_COLORECTAL_CANCER

CYCS MAPK8 MAPK9 MAPK10

1.16e-0373894M39758
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

CACNA1B GRIA1 GRIA3 GRIA4

1.16e-0373894MM16641
PathwaySIG_CD40PATHWAYMAP

MAPK8 MAPK9 MAPK10

1.26e-0334893M12705
PathwayREACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN

CMAS ALG9 ALG3 ALG6

1.41e-0377894MM15118
PathwayWP_REGULATORY_CIRCUITS_OF_STAT3_SIGNALING

LIFR MAPK8 MAPK9 MAPK10

1.48e-0378894M39824
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CACNA1B STK3 FGF11 CACNA1G MAPK8 MAPK9 MAPK10

1.48e-03267897M10792
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

MAPK8 MAPK9 MAPK10

1.49e-0336893M39699
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING

MAPK8 MAPK9 MAPK10

1.49e-0336893M39908
PathwayREACTOME_CELLULAR_SENESCENCE

EED ANAPC1 MAPK8 MAPK9 MAPK10 CABIN1

1.53e-03197896M27188
PathwayREACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN

CMAS ALG9 ALG3 ALG6

1.55e-0379894M897
PathwayKEGG_FC_EPSILON_RI_SIGNALING_PATHWAY

BTK MAPK8 MAPK9 MAPK10

1.55e-0379894M11816
PathwayWP_OREXIN_RECEPTOR_PATHWAY

TOX GRIA1 GRIA2 MAPK8 MAPK9 DAGLA

1.66e-03200896M48048
PathwayREACTOME_MYD88_MAL_TIRAP_CASCADE_INITIATED_ON_PLASMA_MEMBRANE

ALPK1 MAPK8 MAPK9 MAPK10

2.04e-0385894MM14645
PathwayKEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION

ANAPC1 MAPK8 MAPK9 MAPK10

2.04e-0385894M3578
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST

STT3A ALG6

2.09e-0311892M47614
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.16e-03144895MM14501
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN11A GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 DAGLA

2.20e-03367898M48346
PathwayWP_WNT_SIGNALING_IN_KIDNEY_DISEASE

MAPK8 MAPK9 MAPK10

2.67e-0344893MM15878
PathwayREACTOME_HEME_BIOSYNTHESIS

HMBS COX15

2.94e-0313892MM14720
PathwayREACTOME_TOLL_LIKE_RECEPTOR_CASCADES

ALPK1 MAPK8 MAPK9 MAPK10 DNM2

2.98e-03155895MM14665
PathwayWP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS

MAPK8 MAPK9 MAPK10

3.04e-0346893M39805
PathwayWP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING

BTK MAPK8 MAPK9

3.23e-0347893M39380
PathwayREACTOME_HEME_BIOSYNTHESIS

HMBS COX15

3.41e-0314892M27059
PathwayREACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE

ALPK1 MAPK8 MAPK9 MAPK10

3.54e-0399894MM14660
PathwayWP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY

MAPK8 MAPK9 MAPK10

3.63e-0349893M39543
PathwayPID_FOXO_PATHWAY

MAPK8 MAPK9 MAPK10

3.63e-0349893M136
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

GRIN2D CYCS

3.92e-0315892M47691
Pubmed

Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

8.26e-127117521368048
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-10411749221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117425337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117417828255
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117424652293
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117412692557
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117412125045
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117410688364
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117417409242
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-104117414561864
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-10411741319477
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA1 GRIA2 GRIA3 GRIA4

1.22e-10411749648857
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.63e-1024117635746896
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

RELN GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.66e-1045117725979088
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA1 GRIA2 GRIA3 GRIA4

6.07e-105117416129400
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA1 GRIA2 GRIA3 GRIA4

6.07e-10511749482932
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

1.16e-091511759481670
Pubmed

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.

GRIA1 GRIA2 GRIA3 GRIA4

4.22e-097117433981040
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA1 GRIA2 GRIA3 GRIA4

4.22e-09711749016303
Pubmed

TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.

GRIA1 GRIA2 GRIA3 GRIA4

4.22e-097117427076426
Pubmed

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

GRIA1 GRIA2 GRIA3 GRIA4

4.22e-097117410407040
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA1 GRIA2 GRIA3 GRIA4

4.22e-09711749651535
Pubmed

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

RELN GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 RIMS1

6.92e-09118117819156168
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA1 GRIA2 GRIA3 GRIA4

8.43e-098117423217150
Pubmed

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

GRIA1 GRIA2 GRIA3 GRIA4

1.51e-089117424292102
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA1 GRIA2 GRIA3 GRIA4

1.51e-08911749051806
Pubmed

JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy.

MAPK8 MAPK9 MAPK10

3.71e-083117330685843
Pubmed

JNK1 is required to preserve cardiac function in the early response to pressure overload.

MAPK8 MAPK9 MAPK10

3.71e-083117316579967
Pubmed

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.

GRIA1 GRIA2 GRIA3

3.71e-083117334426577
Pubmed

Specific pathophysiological functions of JNK isoforms in the brain.

MAPK8 MAPK9 MAPK10

3.71e-083117315673436
Pubmed

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.

GRIA1 GRIA2 GRIA3

3.71e-083117315144856
Pubmed

Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells.

MAPK8 MAPK9 MAPK10

3.71e-083117323485395
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA2 GRIA3 GRIA4

3.71e-083117318163426
Pubmed

Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.

GRIA1 GRIA2 GRIA3

3.71e-083117312700243
Pubmed

Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.

GRIA1 GRIA3 GRIA4

3.71e-083117312172541
Pubmed

Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model.

MAPK8 MAPK9 MAPK10

3.71e-083117317056565
Pubmed

The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases.

MAPK8 MAPK9 MAPK10

3.71e-083117334502556
Pubmed

Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder.

GRIA1 GRIA2 GRIA4

3.71e-083117322122651
Pubmed

Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning.

MAPK8 MAPK9 MAPK10

3.71e-083117320926661
Pubmed

Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting.

GRIA1 GRIA2 GRIA3

3.71e-083117328630296
Pubmed

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis.

MAPK8 MAPK9 MAPK10

3.71e-083117319609503
Pubmed

NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity.

GRIA1 GRIA2 GRIA3

3.71e-083117336070750
Pubmed

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia.

GRIA1 GRIA2 GRIA4

3.71e-083117322094384
Pubmed

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.

GRIA1 GRIA2 GRIA3

3.71e-083117332569783
Pubmed

Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex.

GRIA1 GRIA2 GRIA3

3.71e-083117336223737
Pubmed

Persistent synaptic scaling independent of AMPA receptor subunit composition.

GRIA1 GRIA2 GRIA3

3.71e-083117323864664
Pubmed

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder.

GRIA1 GRIA2 GRIA4

3.71e-083117322057216
Pubmed

Activation of c-Jun N-terminal kinase mediates gp120IIIB- and nucleoside analogue-induced sensory neuron toxicity.

MAPK8 MAPK9 MAPK10

3.71e-083117315246824
Pubmed

A critical role of neural-specific JNK3 for ischemic apoptosis.

MAPK8 MAPK9 MAPK10

3.71e-083117314657393
Pubmed

SAPKgamma/JNK1 and SAPKalpha/JNK2 mRNA transcripts are expressed in early gestation human placenta and mouse eggs, preimplantation embryos, and trophoblast stem cells.

MAPK8 MAPK9 MAPK10

3.71e-083117315474087
Pubmed

AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy.

GRIA1 GRIA2 GRIA3

3.71e-083117315145077
Pubmed

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain.

GRIA1 GRIA2 GRIA3

3.71e-083117328290985
Pubmed

c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.

MAPK8 MAPK9 MAPK10

3.71e-083117314517246
Pubmed

Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.

GRIA1 GRIA2 GRIA3

3.71e-083117326585043
Pubmed

Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors.

GRIA1 GRIA2 GRIA3

3.71e-083117314687553
Pubmed

Synaptic homeostasis requires the membrane-proximal carboxy tail of GluA2.

GRIA1 GRIA2 GRIA3

3.71e-083117329180434
Pubmed

Synaptic AMPA receptor plasticity and behavior.

GRIA1 GRIA3 GRIA4

3.71e-083117319217372
Pubmed

Knockout of c-Jun N-terminal kinases 1, 2 or 3 isoforms induces behavioural changes.

MAPK8 MAPK9 MAPK10

3.71e-083117323428746
Pubmed

Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach.

GRIA1 GRIA2 GRIA3

3.71e-083117319409270
Pubmed

Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1.

GRIA1 GRIA2 GRIA3

3.71e-083117321135237
Pubmed

LTP requires a reserve pool of glutamate receptors independent of subunit type.

GRIA1 GRIA2 GRIA3

3.71e-083117323235828
Pubmed

Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.

NEK2 MAPK8 MAPK9 MAPK10

3.94e-0811117415123655
Pubmed

Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.

GRIN2D MAPK8 MAPK9 MAPK10

3.94e-0811117416481105
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRIA1 GRIA2 GRIA3 GRIA4

5.90e-0812117411891216
Pubmed

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.

GRIA1 GRIA2 GRIA3 GRIA4

8.50e-0813117425218043
Pubmed

Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.

ERN1 MAPK8 MAPK9 MAPK10

1.19e-0714117419805353
Pubmed

From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development.

RELN GRIA1 GRIA2 GRIA4

1.19e-0714117416880397
Pubmed

Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).

MAPK8 MAPK9 MAPK10

1.48e-074117315228592
Pubmed

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.

GRIA2 GRIA3 GRIA4

1.48e-074117328608780
Pubmed

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis.

MAPK8 MAPK9 MAPK10

1.48e-074117312818176
Pubmed

JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells.

MAPK8 MAPK9 MAPK10

1.48e-074117320525557
Pubmed

JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases.

MAPK8 MAPK9 MAPK10

1.48e-07411739393873
Pubmed

c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.

MAPK8 MAPK9 MAPK10

1.48e-074117315528206
Pubmed

Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus.

GRIA1 GRIA2 GRM5

1.48e-07411739619499
Pubmed

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

GRIA2 GRIA3 GRIA4

1.48e-074117310027300
Pubmed

A selective small-molecule inhibitor of c-Jun N-terminal kinase 1.

MAPK8 MAPK9 MAPK10

1.48e-074117319527717
Pubmed

The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function.

GRIA1 GRIA2 GRIA3

1.48e-074117323664612
Pubmed

The Role of AMPARs in the Maturation and Integration of Caudal Ganglionic Eminence-Derived Interneurons into Developing Hippocampal Microcircuits.

GRIA1 GRIA2 GRIA3

1.48e-074117330931998
Pubmed

LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes.

GRIA1 GRIA2 GRIA3

1.48e-074117329581259
Pubmed

Distribution of alpha-amino-3-hydroxy-5-methyl-4 isoazolepropionic acid and N-methyl-D-aspartate receptor subunits in the vestibular and spiral ganglia of the mouse during early development.

GRIA1 GRIA2 GRIA3

1.48e-074117312414093
Pubmed

Positive signaling through CD72 induces mitogen-activated protein kinase activation and synergizes with B cell receptor signals to induce X-linked immunodeficiency B cell proliferation.

BTK MAPK8 MAPK9

1.48e-074117311466342
Pubmed

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons.

GRIA1 GRIA2 GRIA3

1.48e-074117326932439
Pubmed

c-JUN N-terminal kinase-1 (JNK1) but not JNK2 or JNK3 is involved in UV signal transduction in human epidermis.

MAPK8 MAPK9 MAPK10

1.48e-074117316824735
Pubmed

Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.

GRIA1 GRIA2 GRIA3

1.48e-074117331231192
Pubmed

Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.

MAPK8 MAPK9 MAPK10

1.48e-074117322372722
Pubmed

AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity.

GRIA1 GRIA2 GRIA3

1.48e-074117331992779
Pubmed

Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein.

MAPK8 MAPK9 MAPK10

1.48e-074117315693750
Pubmed

A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.

MAPK8 MAPK9 MAPK10

1.48e-074117310471813
Pubmed

LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory.

GRIA1 GRIA2 GRIA4

1.48e-074117329915039
Pubmed

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.

GRIA1 GRIA2 GRIA3

1.48e-074117332831170
Pubmed

Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit.

GRIA1 GRIA2 GRIA3

1.48e-074117329515177
Pubmed

APP upregulation contributes to retinal ganglion cell degeneration via JNK3.

MAPK8 MAPK9 MAPK10

1.48e-074117329238071
Pubmed

Cortical interneurons require Jnk1 to enter and navigate the developing cerebral cortex.

MAPK8 MAPK9 MAPK10

1.48e-074117324899703
Pubmed

AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62.

GRIA1 GRIA2 GRIA3

1.48e-074117319004011
Pubmed

PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.

GRIA1 GRIA2 GRIA3 GRIA4

2.15e-0716117416055064
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

3.36e-0781117622723691
Pubmed

BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2.

RELN GRIA1 GRIA2 GRIA3

3.59e-0718117412588844
Pubmed

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

GRIA1 GRIA2 GRIA3 GRIA4

3.59e-0718117418311135
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FRAS1 GRIA1 GRIA2 GRIA3

3.59e-0718117414730302
Pubmed

Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission.

GRIA1 GRIA2 GRIA3

3.69e-075117331492534
InteractionGRIA3 interactions

GRIA1 GRIA2 GRIA3 GRIA4 ALG9

4.68e-06431165int:GRIA3
Cytoband11q23.3

HMBS STT3A ATP5MG PHLDB1

4.94e-0578117411q23.3
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA1 GRIA2 GRIA3 GRIA4

3.93e-1048241200
GeneFamilyMitogen-activated protein kinases

MAPK8 MAPK9 MAPK10

2.49e-0513823651
GeneFamilyRegulating synaptic membrane exocytosis family|PDZ domain containing

RIMS1 RIMS2

1.21e-044822833
GeneFamilyDolichyl D-mannosyl phosphate dependent mannosyltransferases|Phosphatidylinositol glycan anchor biosynthesis

ALG9 ALG3

7.17e-049822430
GeneFamilyMAGE family

MAGEA3 MAGEA6 MAGEA9

7.87e-04408231136
GeneFamilyUbiquitin specific peptidases

USP6 USP8 USP4

2.10e-0356823366
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SWAP70 PRKD3 PHLDB1 BTK DNM2

2.45e-03206825682
GeneFamilyCalcium voltage-gated channel subunits

CACNA1B CACNA1G

6.15e-0326822253
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

MRC1 SCARB1

6.63e-03278221253
GeneFamilyTransient receptor potential cation channels

TRPC4 PKD2

7.12e-0328822249
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

ARL8A ARL8B

8.68e-0331822357
CoexpressionHOLLERN_EMT_BREAST_TUMOR_UP

MRC1 FN1 APBB2 NEK9 PHKA1 PHLDB1 ANGPTL2

3.24e-061401177M617
CoexpressionHOLLERN_EMT_BREAST_TUMOR_UP

MRC1 FN1 APBB2 NEK9 PHKA1 PHLDB1 ANGPTL2

4.28e-061461177MM964
CoexpressionFIRESTEIN_PROLIFERATION

AKAP6 EPHA6 STK3 BTK MAPK8 STK24 TRIB1

9.95e-061661177M5354
CoexpressionDCA_UP.V1_UP

GRIA1 GRIN2D GRM5 PHLDB1 MAPK8 CABIN1 RIMS2

2.08e-051861177M2762
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500

RELN ADAMTSL1 TRIB2 SLC37A3 GRIA1 COX15 GRIA4 FAP

1.56e-052061148gudmap_developingKidney_e15.5_Peripheral blastema_500_k2
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500

RELN ADAMTSL1 TRIB2 SLC37A3 GRIA1 COX15 GRIA4 CNTLN FAP DCUN1D1 ANAPC1

1.69e-0542111411gudmap_developingKidney_e15.5_Peripheral blastema_500
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_100

RELN ADAMTSL1 GRIA1 GRIA4 FAP

1.76e-05601145gudmap_developingKidney_e15.5_Peripheral blastema_100_k3
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_200

RELN ADAMTSL1 GRIA1 COX15 GRIA4 FAP

3.85e-051161146gudmap_developingKidney_e15.5_Peripheral blastema_200_k2
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2

ADAMTSL1 TRIB2 FN1 TOX SWAP70 GRIA3 ALPK1 CNTLN GBA2 PTGFRN LRIG3 FAP PHLDB1 SCARB1 JOSD1 CACNA1G RIMS1 DAGLA

9.36e-05122811418facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_100

RELN ADAMTSL1 GRIA1 GRIA4 FAP

1.06e-04871145gudmap_developingKidney_e15.5_Peripheral blastema_100
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

ADAMTSL1 TRIB2 FN1 TOX GRIA3 GRIA4 ALPK1 CNTLN PTGFRN NEK9 LRIG3 FAP PKD2 FGF11 CACNA1G RIMS1 MAPK9

1.32e-04114811417facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1B RELN ADAMTSL1 EPHA6 GRIA4 GRM5 RIMS2

1.32e-071481177d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1B RELN ADAMTSL1 EPHA6 GRM5 XIRP2 RIMS1

2.16e-0715911775335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 FN1 TRPC4 HMCN2 PKD2 MACF1 RIMS1

6.69e-07188117734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 FN1 TRPC4 HMCN2 PKD2 MACF1 RIMS1

6.94e-0718911776b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 BCAS3 STK3 MACF1 SLC5A12 MAPK8 MAPK10

7.71e-071921177e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B GRIA1 GRIA2 GRIA3 GRM5 RIMS1 RIMS2

8.85e-071961177676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B GRIA1 GRIA2 GRIA3 GRM5 RIMS1 RIMS2

9.47e-0719811776d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B GRIA1 GRIA2 GRIA3 GRM5 RIMS1 RIMS2

9.47e-0719811774ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

STXBP5 CHIT1 GBA2 NEK2 ARSD ALG9 TRIB1

1.01e-062001177118321ac443feb42aee171baccfc4610f00a8822
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 GRIA4 PTGFRN LRIG3 C2CD4D DNASE1L2

4.47e-061621176b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FN1 TOX LMO7DN LRIG3 RIMS1 MAPK10

9.84e-0618611767def03dd856b765bd3f493288641981c4f7fd26e
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

TOX BCAS3 APBB2 STK3 MAPK10 ACOXL

1.33e-051961176ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1B GRIA2 GRIA4 USP6 RIMS2 KCNT1

1.33e-0519611764bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCellB_cells-Plasmablasts|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PSAT1 ERN1 STT3A TMEM147 FUCA2 TRIB1

1.40e-051981176c6cab47885be74a64351f843a741dea6d911bde4
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B GRIA1 GRIA2 GRM5 RIMS1 RIMS2

1.40e-051981176c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B GRIA2 GRM5 RIMS1 MAPK10 RIMS2

1.40e-0519811768ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TOX BCAS3 APBB2 STK3 MAPK10 ACOXL

1.40e-0519811761996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B GRIA1 GRIA2 GRM5 RIMS1 RIMS2

1.40e-0519811760ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1B RELN GRIA2 GRM5 RIMS2

4.78e-0515011750205318a870e091add66ee4305747dda9f51510d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1B FRAS1 EPHA6 NEB RIMS2

6.89e-051621175bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1B GRIA4 NEK2 SLC5A12 RIMS2

7.51e-0516511750ae39c9a6d1265d65dc0660924612cfe11e489ec
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1B GRIA4 NEK2 SLC5A12 RIMS2

7.51e-051651175686cf89077cc7b744a6127de2b34d8c27da8b6c4
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1B GRIA4 NEK2 SLC5A12 RIMS2

7.51e-051651175a5ed8c331d5551cd8bce50bdc31cb893218317cd
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 TRPC4 GRIA3 PHLDB1 MAPK10

8.41e-051691175c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRIB2 DHX58 TOX ERN1 IL23R

9.13e-051721175a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL1 TRPC4 GRIA3 OR52I1 PHLDB1

9.64e-051741175f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 RELN ADAMTSL1 GRIA2 TMCO4

9.91e-05175117584d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 RELN ADAMTSL1 GRIA2 TMCO4

9.91e-051751175a00c6fa9b33640710dd05a3799031147196f0986
ToppCelldroplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 EPHA6 PHLDB1 ADGRG2 C2CD4D

1.02e-041761175533d544852038c0612aacf87f4b1c88ff7aace82
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RELN ADAMTSL1 GRIA2 KCNT1

1.02e-041761175057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RELN ADAMTSL1 GRIA2 KCNT1

1.02e-041761175b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NUGGC PSAT1 STT3A NEK2 ACOXL

1.05e-041771175d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NUGGC PSAT1 STT3A NEK2 ACOXL

1.05e-04177117565e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX PTPN22 NEB ANGPTL2 IL23R

1.07e-041781175888add8935ef3aef9b6693c5698e9d1842e66337
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX PTPN22 NEB ANGPTL2 IL23R

1.07e-04178117543eda32af2e5e28a92421612d0a4c21e5427a772
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TOX TRPC4 GRIA2 DNAJC22 ADGRG2

1.13e-041801175a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 ADAMTSL1 RIMS1 MAPK10 ACOXL

1.13e-041801175b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 FN1 TRPC4 GRIA1 ADGRG2

1.13e-041801175137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 FN1 TRPC4 GRIA1 ADGRG2

1.13e-041801175cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

FN1 APBB2 TMC4 MAPK10 FRMD3

1.19e-0418211752075efeae633550fb2eb026d0dfd741c8252482e
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

RELN GRIA4 GRIN2D NEB FGF11

1.19e-041821175b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAT1 FN1 GRIA3 YTHDC2 USP8

1.19e-041821175bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TOX ERN1 PTPN22 C2CD4D IL23R

1.19e-0418211756bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

AKAP6 FN1 TRPC4 HMCN2 PKD2

1.22e-041831175818fd886e0188091310825f9145fa53328f2c979
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHA6 TRPC4 GRIN2D PHKA1 LRIG3

1.22e-041831175121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL1 EPHA6 TMC4 WDR49 FRMD3

1.22e-041831175c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN ADAMTSL1 USP6 C2CD4D RIMS2

1.25e-04184117530ca56d64c961127e26122613e35aa2b46fde2df
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX PTPN22 NEB STK3 ACOXL

1.25e-0418411752c8e9ddce3e60302965dcf9dee77c4fe33e4071d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 FN1 EPHA6 RIMS1 FRMD3

1.29e-041851175f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FN1 TOX CACNA1G MAPK10 CABIN1

1.29e-0418511751ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA1 GRIA4 CHIT1 RIMS1 RIMS2

1.32e-041861175a1ab273b01971d6a892912560d387685dd657179
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA1 GRIA4 CHIT1 RIMS1 RIMS2

1.35e-041871175ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

FRAS1 FN1 TRPC4 GRIA1 MACF1

1.35e-04187117592d468dde81125d51daf7abd4703741abe1ab91c
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 FN1 GRIA2 LIFR LRIG3

1.39e-041881175ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

PSAT1 TRIB2 TOX LRIG3 ACOXL

1.39e-041881175ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1B GRIA2 DNAJC22 RIMS1 RIMS2

1.39e-041881175c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SWAP70 APBB2 PRKD3 USP8 BTK

1.42e-041891175b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ADAMTSL1 EPHA6 WDR49 FRMD3

1.42e-0418911757659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FN1 LMO7DN FAP ANGPTL2 ADGRG2

1.42e-041891175c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NUGGC STT3A FUCA2 TRIB1 ACOXL

1.46e-04190117576b747bafff09bf8375a5717c9f213cbfb405bac
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FN1 TOX GRIA1 LIFR MAPK10

1.46e-0419011757986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

FRAS1 FN1 BCAS3 LIFR MACF1

1.46e-04190117571e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ADAMTSL1 EPHA6 WDR49 FRMD3

1.49e-04191117560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellsevere-Lymphocytic-Plasmablast|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NUGGC PSAT1 STT3A CYCS ACOXL

1.49e-04191117573660d762c9d451980c21adc426db6670bcaf37f
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

STT3A ALG3 FUCA2 TRIB1 ACOXL

1.49e-0419111757b4b5d90d1023d03239ed986f273afa734d3124d
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NUGGC PSAT1 ERN1 STT3A TRIB1

1.49e-0419111753df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EPHA6 C1RL STK3 PHLDB1 MAPK10

1.49e-04191117570c067c54084bfb02c29bab085f4defd477194fb
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 FRAS1 XIRP2 SLC22A1 MAPK10

1.53e-0419211750bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ADAMTSL1 EPHA6 WDR49 FRMD3

1.53e-041921175b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC RELN ERN1 STT3A TRIB1

1.53e-0419211756417468829517a0f6e04e7e44eec1622001d4c5c
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 FRAS1 XIRP2 SLC22A1 MAPK10

1.53e-041921175d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FRAS1 FN1 GRIA1 FAP MACF1

1.53e-04192117562904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA1 GRIA2 GRIA3 GRM5 MAPK10

1.57e-041931175be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PSAT1 TOX ERN1 HMBS TRIB1

1.57e-0419311751f50823bd7ef00500d9d81f0f5c2f6c940c4b1a6
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FN1 EPHA6 LIFR FAP PHLDB1

1.57e-0419311755e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LMO7DN PTGFRN FAP ANGPTL2 ADGRG2

1.57e-04193117509de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA1 GRIA2 GRIA3 GRM5 MAPK10

1.57e-0419311750c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA1 GRIA2 GRIA3 GRM5 MAPK10

1.57e-0419311758689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FN1 BCAS3 TRPC4 GRIA1 MACF1

1.57e-0419311755896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellPCW_05-06-Epithelial-Epithelial_airway|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL1 EPHA6 TMC4 WDR49 FRMD3

1.57e-041931175af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PSAT1 TOX ERN1 HMBS TRIB1

1.57e-041931175b9c00df1b216eaa4283315713f1c9ef552d3d435
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FN1 APBB2 GRIA1 LIFR FAP

1.60e-04194117599577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAMTSL1 EPHA6 TMC4 WDR49 FRMD3

1.60e-041941175b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ADAMTSL1 EPHA6 WDR49 FRMD3

1.60e-041941175f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FN1 APBB2 GRIA1 LIFR FAP

1.64e-04195117570387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCellfacs-Aorta-Heart-3m-Endothelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIB2 APBB2 LIFR SCARB1 MACF1

1.64e-0419511758493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

FRAS1 FN1 TRPC4 APBB2 GRIA1

1.64e-041951175603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellfacs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIB2 APBB2 LIFR SCARB1 MACF1

1.64e-0419511755e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 TRPC4 APBB2 GRIA2 FAP

1.68e-041961175b8759e6231e0254797d6c30930407b79440c57bb
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 TRPC4 GRIA3 LIFR MAPK10

1.68e-0419611752ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADAMTSL1 TRPC4 PTGFRN ANGPTL2 RIMS1

1.68e-04196117557df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GRIA2 LRIG3 FAP ANGPTL2 ADGRG2

1.68e-041961175ee45e4de9d706ec87094e87f47d3e514539b8092
ToppCell10x3'2.3-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GRIA2 LRIG3 FAP ANGPTL2 ADGRG2

1.68e-041961175fa4a85a3cd52df0da5dfedc0e584e9df8c61ce89
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RELN HMBS ZDHHC17 CMAS DCUN1D1

1.72e-041971175d8f99a9f2367c8bc9308b0c64d0226875262927a
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 FN1 TRPC4 HMCN2 PKD2

1.72e-041971175bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellPCW_10-12|World / Celltypes from embryonic and fetal-stage human lung

FN1 LIFR USP6 FAP MACF1

1.72e-04197117547fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FRAS1 FN1 GRIA1 LIFR MACF1

1.72e-0419711750034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-osteoclast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

AKAP6 PTPN22 ATP5MG CYCS TMEM147

1.72e-0419711751bf69db7e830315c8fa85e6e85b0cb94014e9169
ToppCell(5)_Fibroblasts-(5)_Fibroblast-G|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

FRAS1 FN1 GRIA1 ADGRG2 MACF1

1.72e-041971175a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRIA2 FAP ANGPTL2 HMCN2 FRMD3

1.76e-04198117512cd9f0bbad8dce5199ebfed1c4a8080710ca055
DrugNs102

MKKS GRIA1 GRIA2 GRIA3 GRIA4 CYCS MAPK8 MAPK9 MAPK10

3.48e-15251179CID005311098
DrugBAPTA

CACNA1B FN1 TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 PRKD3 FAP CYCS MAPK8 MAPK9 MAPK10 CABIN1

1.08e-1132411716CID000104751
Drug6,7-dinitroquinoxaline

MKKS GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D MAPK10

3.02e-10331177CID002724608
DrugGYKI 52466

MKKS GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 MAPK10

5.90e-10581178CID000003538
Drug3-pyridazinol 1-oxide

GRIA1 GRIA2 GRIA3 GRIA4

6.62e-1041174CID000574311
DrugYM90K

GRIA1 GRIA2 GRIA4 GRIN2D GRM5 CABIN1

1.52e-09231176CID005486547
DrugCGP 39653

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.02e-09241176CID006437837
Drug1NaPP1

RELN GRIA1 GRIA2 GRIA3 GRIA4

2.53e-09121175CID000004877
DrugAC1L1YEG

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID000063114
DrugChicago acid

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID000065740
DrugCHEBI:570577

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID011334126
Drug1-BCP

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID000001370
Drugirampanel

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID003038472
DrugLY395153

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID000656707
Drugbeta-N-oxalylaminoalanine

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID000107978
Drug5-h PCA

GRIA1 GRIA2 GRIA3 GRIA4

3.30e-0951174CID000129091
DrugAC1NUW3V

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

6.98e-09291176CID005462126
DrugLY293558

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

8.69e-09301176CID000127894
DrugAC1L32TU

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

8.69e-09301176CID000107831
Drugthiokynurenic acid

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

9.48e-09151175CID003035667
DrugYM928

GRIA1 GRIA2 GRIA3 GRIA4

9.86e-0961174CID006918393
Drug2cmo

GRIA1 GRIA2 GRIA3 GRIA4

9.86e-0961174CID006914597
Drug4-methylglutamic acid

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.07e-08311176CID000005365
Drugeliprodil

LARS1 GRIA1 GRIA2 GRIA4 GRIN2D GRM5

1.07e-08311176CID000060703
Drugalpha-methyl-4-carboxyphenylglycine

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.31e-08321176CID000001222
DrugLY233536

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

1.37e-08161175CID000126239
DrugD-CPPene

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.93e-08341176CID006435801
Drug7-Cl-Thio-Kyna

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

1.94e-08171175CID003035668
Drughexachlorophene

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 ALG6

2.08e-08901178CID000003598
Drug4,6-dichloroindole-2-carboxylic acid

GRIA1 GRIA2 GRIA3 GRIA4

2.29e-0871174CID000127988
Drugthio-ATPA

GRIA1 GRIA2 GRIA3 GRIA4

2.29e-0871174CID005289517
Drugfludelone

CYCS MAPK8 MAPK9 MAPK10

2.29e-0871174CID006918712
Drugkainite

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D MAPK10

2.33e-08351176CID000164810
DrugMNQX

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

2.67e-08181175CID000130818
DrugR,S)-AMPA

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.78e-08361176CID000001221
DrugC6H12NO5P

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.78e-08361176CID000104962
DrugLY382884

GRIA1 GRIA2 GRIA3 GRIA4 GRM5

3.61e-08191175CID000656723
DrugL-BMAA

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

3.91e-08381176CID000028558
DrugCGS 19755

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

3.91e-08381176CID000068736
Drughomoibotenic acid

GRIA1 GRIA2 GRIA3 GRIA4

4.56e-0881174CID000194385
Drug1-hydroxypyrazole

GRIA1 GRIA2 GRIA3 GRIA4

4.56e-0881174CID003016733
Drug1-hydroxyimidazole

GRIA1 GRIA2 GRIA3 GRIA4

4.56e-0881174CID003614351
Drug2,3-PDCA

GRIA1 GRIA2 GRIA3 GRIA4

4.56e-0881174CID000127037
DrugHA-966

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

4.60e-08391176CID000001232
DrugDETC-MeSO

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

4.60e-08391176CID003035711
DrugIDRA 21

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

4.79e-08201175CID000003688
DrugL000369

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

6.28e-08411176CID003931705
DrugAC1NNRU4

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

6.28e-08411176CID005126051
DrugNS 102

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

8.07e-08221175CID005282252
DrugCX516

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D

8.07e-08221175CID000148184
Drug1m5b

GRIA1 GRIA2 GRIA3 GRIA4

8.18e-0891174CID000447081
DrugLy294486

GRIA1 GRIA2 GRIA3 GRIA4

8.18e-0891174CID005311255
Drugisothiazol-3-one

GRIA1 GRIA2 GRIA3 GRIA4

8.18e-0891174CID000096917
DrugLY341495

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

8.45e-08431176CID006324636
DrugJoro spider toxin

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

8.45e-08431176CID000119582
DrugPHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT_HG-U133A

GRIA3 PTPN22 ALPK1 ANGPTL2 CACNA1G RIMS1 MAPK10 DAGLA STK24 DNASE1L2

8.62e-08200117103773_UP
Drugglutamate

CACNA1B PSAT1 RELN TRPC4 LARS1 HMBS GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 PRKD3 DHFR2 CYCS PKD2 CACNA1G RIMS1 MAPK10 CABIN1

9.42e-0896211720CID000000611
DrugAC1L9FMM

GRIA1 GRIA2 GRIA3 GRIA4 ALPK1 GRIN2D GRM5

9.72e-08731177CID000444055
Drug7-chlorokynurenic acid

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.12e-07451176CID000001884
Drug2-amino-3-phosphonopropionic acid

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 PRKD3

1.29e-07761177CID000003857
Drugbenzothiazol-2-ylacetonitrile

MAPK8 MAPK9 MAPK10

1.32e-0731173CID000342465
DrugBenzoates

GRIA1 GRIA2 GRIA3 GRIA4

1.36e-07101174ctd:D001565
Druggavestinel

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

1.61e-07251175CID006450546
Drugmethylenecyclopropylglycine

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

1.89e-07491176CID000441452
DrugJ-ST

GRIA1 GRIA2 GRIA3 GRIA4

2.13e-07111174CID005288655
DrugYM872

GRIA1 GRIA2 GRIA3 GRIA4

2.13e-07111174CID000148200
Drug0-ol

GRIA1 GRIA2 GRIA3 GRIA4

2.13e-07111174CID000069892
Drugsym 2206

GRIA1 GRIA2 GRIA3 GRIA4

2.13e-07111174CID005039877
Druggabapentin

CACNA1B PSAT1 GRIA1 GRIA2 GRIA4 GRIN2D GRM5 PKD2 CACNA1G

2.30e-071691179CID000003446
DrugDNQX

MKKS GRIA1 GRIA2 GRIA4 GRIN2D GRM5 MAPK10

2.37e-07831177CID003899541
DrugAC1L63MU

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 PTGFRN PRKD3 FAP MAPK8 MAPK9 MAPK10

2.38e-0734711712CID000285703
DrugLY354740

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.41e-07511176CID000114827
DrugL-689,560

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

2.42e-07271175CID000121918
DrugD-N-Q

MKKS GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.58e-07841177CID000003140
DrugAC1L1EKQ

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

2.72e-07521176CID000002834
DrugNSC618487

FN1 EPHA6 ERN1 APBB2 GRIN2D GRM5 NEK9 STT3A PRKD3 NEK2 SCARB1 BTK CYCS MAPK8 MAPK9 MAPK10 CABIN1 DAGLA STK24

2.82e-0793311719CID000005279
DrugC-PP

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

2.94e-07281175CID000001228
Drugaptiganel

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

2.94e-07281175CID000060839
Drugriluzole

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 PKD2 CACNA1G

2.94e-071741179CID000005070
Drugmemantine

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 CYCS

3.03e-07861177CID000004054
DrugKN-62

CACNA1B FN1 GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D PRKD3 MAPK8 CABIN1

3.16e-0723011710CID000003838
DrugAtpa

GRIA1 GRIA2 GRIA3 GRIA4

3.18e-07121174CID000002252
DrugC-X6

GRIA1 GRIA2 GRIA3 GRIA4

3.18e-07121174CID005288002
Drugrufinamide

GRIA1 GRIA2 GRIA3 GRIA4 CACNA1G

3.54e-07291175CID000129228
Drugketobemidone

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

3.54e-07291175CID000010101
Drug3-(1H-pyrrole-2-carboxylate

AKAP6 CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRM5 PRKD3 PKD2 CABIN1

3.56e-0723311710CID000005114
Drugcis-2,3-piperidine dicarboxylic acid

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

4.23e-07301175CID000001226
DrugGYKI 53655

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

4.23e-07301175CID000126757
Drugaurintricarboxylic acid

GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 DNASE1L2

4.47e-07911177CID000002259
Drug2-amino-4-phosphonobutyric acid

CACNA1B GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5

4.47e-07911177CID000002207
DrugNaspm

GRIA1 GRIA2 GRIA3 GRIA4

4.57e-07131174CID000129695
DrugNPC 12626

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

5.02e-07311175CID000108099
DrugLY235959

GRIA1 GRIA2 GRIA4 GRIN2D GRM5

5.02e-07311175CID000131938
DrugJNK inhibitor VIII

CYCS MAPK9 MAPK10

5.27e-0741173CID011624601
Drugsunifiram

GRIA1 GRIA2 GRIA4

5.27e-0741173CID004223812
Drug4-(chloromethyl)-3-methoxy-5-methylisoxazole

GRIA1 GRIA2 GRIA4

5.27e-0741173CID011105661
Drug3-isoxazolol

GRIA1 GRIA2 GRIA4

5.27e-0741173CID009964065
DrugMPEP

ERN1 GRIA1 GRIA2 GRIA4 GRIN2D GRM5

5.84e-07591176CID003025961
DrugKW-6002

GRIA1 GRIA2 GRIA3 GRIA4 GRM5

5.93e-07321175CID005311037
Drugquinoxaline-2,3-dione

GRIA1 GRIA2 GRIA3 GRIA4

6.37e-07141174CID011469229
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA1 GRIA2 GRIA3 GRIA4

3.98e-07161164DOID:331 (implicated_via_orthology)
Diseaseneurodegenerative disease (implicated_via_orthology)

TRPC4 GRIA1 GRIA2 GRIA3 GRIA4 STK3

2.42e-051451166DOID:1289 (implicated_via_orthology)
DiseaseNF-kappa-B essential modulator measurement

STK3 STK24

4.58e-0531162EFO_0010597
DiseaseIntellectual Disability

AKAP6 CACNA1B GRIA1 GRIA2 GRIN2D ZMIZ1 STT3A MACF1 CACNA1G

7.07e-054471169C3714756
Diseaselevel of chitinase-3-like protein 1 in blood serum

CHIT1 TRIB1

9.15e-0541162OBA_2041005
Diseaseschizophrenia (implicated_via_orthology)

RELN GRM5 RIMS1 RIMS2

1.52e-04681164DOID:5419 (implicated_via_orthology)
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

ERN1 PTPN22 ZMIZ1 TMCO4 FAP TRIB1 IL23R

1.71e-042951167EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
DiseaseSchizophrenia

CACNA1B PSAT1 RELN GRIA1 GRIA2 GRIA3 GRIA4 GRIN2D GRM5 LIFR MAPK8 RIMS2

1.91e-0488311612C0036341
DiseasePsychosexual Disorders

GRIA1 GRIA3

2.27e-0461162C0033953
DiseaseHypoactive Sexual Desire Disorder

GRIA1 GRIA3

2.27e-0461162C0020594
DiseaseSexual Arousal Disorder

GRIA1 GRIA3

2.27e-0461162C0036902
DiseaseFrigidity

GRIA1 GRIA3

2.27e-0461162C0016722
DiseaseOrgasmic Disorder

GRIA1 GRIA3

2.27e-0461162C0029261
Diseaselethal congenital contracture syndrome (is_implicated_in)

NEK9 DNM2

3.18e-0471162DOID:0060558 (is_implicated_in)
Diseasepulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension

STK3 STK24 FRMD3

3.53e-04351163EFO_0000537, EFO_0005763, EFO_0006335, EFO_0006336
DiseaseCongenital disorder of glycosylation

ALG9 ALG3 ALG6

4.52e-04381163cv:C0282577
Diseaserheumatoid arthritis, Crohn's disease

PTPN22 ZMIZ1 IL23R

4.52e-04381163EFO_0000384, EFO_0000685
Diseaseankylosing spondylitis

AKAP6 ZMIZ1 USP8 IL23R

4.66e-04911164EFO_0003898
DiseasePolycystic Kidney, Autosomal Dominant

ALG9 PKD2

5.42e-0491162C0085413
Disease2-hydroxystearate measurement

STK3 STK24

5.42e-0491162EFO_0021059
Diseasesusceptibility to childhood ear infection measurement

EPHA6 STXBP5 STK3 USP4 STK24

5.89e-041711165EFO_0007904
DiseaseGraves ophthalmopathy (is_implicated_in)

PTPN22 IL23R

6.75e-04101162DOID:0081120 (is_implicated_in)
DiseaseMyopia

AKAP6 SCN11A FRAS1 ADAMTSL1 BCAS3 TRPC4 GRIA4

8.41e-043851167HP_0000545
DiseaseGlioblastoma Multiforme

FN1 ERN1 PRKD3 MAPK8

9.82e-041111164C1621958
Diseasepsychological resilience measurement

TOX CNTLN

9.86e-04121162EFO_0009945
DiseaseTrigeminal Neuralgia

MAPK8 MAPK9

9.86e-04121162C0040997
DiseaseSecondary Trigeminal Neuralgia

MAPK8 MAPK9

9.86e-04121162C0393787
DiseaseTrigeminal Neuralgia, Idiopathic

MAPK8 MAPK9

9.86e-04121162C0393786
Diseaseglucose metabolism measurement, age-related hearing impairment

TOX LRIG3 DPY19L4

1.14e-03521163EFO_0005782, EFO_0009367
DiseaseCocaine-Related Disorders

GRIA1 GRIA2 GRM5 SCARB1

1.19e-031171164C0236736
Diseaselymphocyte measurement

ERN1 BCAS3 STT3A ANAPC1

1.19e-031171164EFO_0803546
Diseaseelectrocardiography

TRIB2 YTHDC2 ZMIZ1 LRIG3 USP8 HMCN2 CACNA1G WDR49

1.20e-035301168EFO_0004327
Disease1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement

TMC4 DAGLA

1.35e-03141162EFO_0022085
Diseasecongenital disorder of glycosylation type I (implicated_via_orthology)

ALG9 ALG6

1.56e-03151162DOID:0050570 (implicated_via_orthology)
Diseasepancreatic adenocarcinoma (is_implicated_in)

MAPK9 MAPK10

1.56e-03151162DOID:4074 (is_implicated_in)
DiseaseYKL40 measurement

CHIT1 TRIB1

1.56e-03151162EFO_0004869
DiseaseCocaine Abuse

GRIA1 GRIA2 GRM5 SCARB1

1.62e-031271164C0009171
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

CACNA1B ADAMTSL1 TOX FAP TRIB1

1.67e-032161165EFO_0007925, EFO_0007927
Diseasefatty acid measurement

GRIA1 TMC4 SLC22A1 SCARB1 MACF1 DAGLA TRIB1

1.72e-034361167EFO_0005110
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

SPG11 SLC22A1 TRIB1

1.80e-03611163EFO_0008317, EFO_0008596, EFO_0020946
Diseaseurolithiasis

BCAS3 STK3 STK24

1.98e-03631163MONDO_0024647
DiseaseCocaine Dependence

GRIA1 GRIA2 GRM5 SCARB1

2.25e-031391164C0600427
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

MRC1 PTPN22 USP8 TMEM147 TRIB1

2.59e-032391165EFO_0010934
Diseasecoronary artery disease

DHX58 FN1 SWAP70 BCAS3 NEK9 STK3 FAP SLC22A1 SCARB1 CABIN1 STK24 TRIB1

2.62e-03119411612EFO_0001645
Diseaseacetate measurement

SPG11 TRIB1

2.78e-03201162EFO_0010112
Diseaseulcerative colitis, Crohn's disease

PTPN22 IL23R

2.78e-03201162EFO_0000384, EFO_0000729
Diseasetissue plasminogen activator measurement, coronary artery disease

STXBP5 SCARB1 TRIB1

2.79e-03711163EFO_0001645, EFO_0004791
DiseaseBipolar Disorder

CACNA1B RELN GRIA1 GRIA2 GRIA3 GRM5 RIMS1

2.84e-034771167C0005586
DiseaseAlzheimer disease

MRC1 RELN BCAS3 PRKD3 CYCS CACNA1G STK24

3.11e-034851167MONDO_0004975
Diseasewellbeing measurement, alcohol consumption measurement

AKAP6 TOX STXBP5

3.13e-03741163EFO_0007869, EFO_0007878
Diseasepsoriasis, type 2 diabetes mellitus

ZMIZ1 FAP IL23R

3.25e-03751163EFO_0000676, MONDO_0005148
Diseaseglioma

GRIA4 PHLDB1

3.36e-03221162EFO_0005543
DiseaseDrugs used in diabetes use measurement

PTPN22 ZMIZ1 PTGFRN MACF1 ACOXL

3.41e-032551165EFO_0009924
Diseaseasparaginase hypersensitivity

CACNA1B GRIA1 ZMIZ1

3.50e-03771163EFO_0004881
DiseaseAlzheimer's disease (is_marker_for)

RELN ATP5MG MAPK8 MAPK9 MAPK10

3.53e-032571165DOID:10652 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YHSLLGNDWKTIGEM

TTF1

631

Q15361
LYGDNVEEMDWLIGK

ARSD

321

P51689
KSGMYGIRELDQKTW

CEBPZOS

61

A8MTT3
VGIWGEGKDMYLILE

APBB2

461

Q92870
EWMLYIQKLLEGQSL

CNTLN

1361

Q9NXG0
WRGQYDVAIKMIKEG

BTK

421

Q06187
LVYFNIIIMWDSKSG

ALG6

486

Q9Y672
WKAYMAEVEGVINGT

ALG3

71

Q92685
GWYMDKTSIAVLGVA

ALG9

206

Q9H6U8
LDSWIALYKMQGLCI

ADGRG2

681

Q8IZP9
GNYKLLVTMEDWSGR

ANGPTL2

361

Q9UKU9
TEVLMWFYVGEIIGK

ATP5MG

81

O75964
LLIMIGYSDGMQVWS

BCAS3

91

Q9H6U6
NGYLEWIFKAEEVML

CACNA1B

386

Q00975
KGLDLEMAIAYWNLV

DCUN1D1

171

Q96GG9
ADMATGVKCGIIYWL

ACOXL

46

Q9NUZ1
GQILQKLGMWYEAAE

ALPK1

201

Q96QP1
VICAIDYTWMLLKDG

PTPN22

236

Q9Y2R2
EELYVAGNMVIWSKG

ANAPC1

91

Q9H1A4
FWKEEMELTLVGLQY

ARL8B

16

Q9NVJ2
FWKEEMELTLVGLQY

ARL8A

16

Q96BM9
YLKQKGLGGAMVWAL

CHIT1

346

Q13231
VILGMGYKENVDIWS

MAPK9

196

P45984
GYKENVDIWSVGCIM

MAPK9

201

P45984
GEILTDMKYGHLWSV

MKKS

466

Q9NPJ1
LGLQWLEYMDGKATN

FRAS1

2446

Q86XX4
YINVGSWDNGELKMD

GRM5

481

P41594
TKAEMLGSVVGNWQY

MAGEA3

131

P43357
TKAEMLGSVVGNWQY

MAGEA6

131

P43360
WEALSVMGVYVGKEH

MAGEA9

221

P43362
LGMGYKENVDIWSVG

MAPK10

236

P53779
GKILVWKELDYGSMT

NEK2

31

P51955
VEKELYTWVNMQGGT

NEK9

386

Q8TD19
TEITKGWLYGLLMLQ

LRIG3

276

Q6UXM1
DTYLLAGGWMLKMTQ

HMCN2

2406

Q8NDA2
MWGQSLYILGSLMAE

PHKA1

401

P46020
ALYLVEEAWAEAGKM

LMO7DN

106

F2Z398
GYLCAMKITEGDLWI

KCNT1

986

Q5JUK3
GVLMQKASLVIQDYW

ADAMTSL1

1476

Q8N6G6
ADTKIWNGMVGELVY

GRIA2

476

P42262
WNGMVGELVYGKADI

GRIA2

481

P42262
ETKIWNGMVGELVYG

GRIA3

486

P42263
IWNGMVGELVYGKAE

GRIA4

481

P48058
VILGMGYKENVDLWS

MAPK8

196

P45983
GYKENVDLWSVGCIM

MAPK8

201

P45983
KGYNRSLDMWSVGVI

PRKD3

751

O94806
MLALGNQVGKLYVWD

EED

376

O75530
VIMAALQTKGYEAVW

JOSD1

86

Q15040
HKYIILGSDGLWNMI

PPM1D

306

O15297
ISLMKGGSKEYWFVL

DNM2

531

P50570
VGGGWMALDEFLVKN

MACF1

7171

Q9UPN3
LEYSVNGGITWNLLM

RELN

2596

P78509
GKVLQVIVWGDYGRM

RIMS1

1616

Q86UR5
WYLGLDKEGQVMKGN

FGF11

171

Q92914
KVLQIIVWGDYGRMD

RIMS2

1336

Q9UQ26
MGSWLKVNGEAIYET

FUCA2

356

Q9BTY2
EWVAGKVHLILYMLG

FRMD3

581

A2A2Y4
GDEEEWLIHYMLGKV

CABIN1

1201

Q9Y6J0
VYLDVIDKWGTDDML

DNASE1L2

186

Q92874
KGIIWGEDTLMEYLE

CYCS

56

P99999
VLASKDGWVDIMYDG

CACNA1G

1481

O43497
YGLAATMIQEGLTWE

GBA2

826

Q9HCG7
SSDGILYMGKKQDIW

ERN1

111

O75460
DSGVVYSVGMQWLKT

FN1

311

P02751
KYLVWVQAANALGME

IL23R

191

Q5VWK5
KVLSYVDWIKGVMNG

C1RL

471

Q9NZP8
MWLLEKAGYKVGAAE

C2CD4D

1

B7Z1M9
LGSLAMVIEGLKYIW

DPY19L4

476

Q7Z388
GEVWGLQMIYKSVKL

DHX58

616

Q96C10
LLLGAKEYSTAVDMW

CDK11A

596

Q9UQ88
WLGHKGMVLSAEYIK

DAGLA

426

Q9Y4D2
DMIWIVGGSSVYKEA

DHFR2

111

Q86XF0
SKLGDDIWIIYEQVM

EMC2

46

Q15006
LLGWYMVKSGLEEKS

COX15

196

Q7KZN9
MKDGQLYLTGGVWSL

HMBS

271

P08397
TKAWNGMVGELVYGR

GRIA1

471

P42261
MAKGLLVTYALWAVG

DNAJC22

1

Q8N4W6
LVSKGNWMAGYTLIT

SLC22A1

211

O15245
VVGMGKGILLTWHYD

LIFR

636

P42702
VGDWLDSIKMGQYKN

EPHA6

966

Q9UF33
IYGMRTKQLLEGIWS

OR52I1

296

Q8NGK6
ELWIGLNDIKIQMYF

MRC1

421

P22897
SELLAVMDGDWTLKY

PTGFRN

461

Q9P2B2
WGKILGLEMNYIVAE

RSPH4A

356

Q5TD94
QEKMTEIGIRSGWKY

NUGGC

611

Q68CJ6
LAWEAKYLMELGNAL

TMCO4

311

Q5TGY1
MGLCWKEVAYLGNEV

CMAS

361

Q8NFW8
KLWIIMEYLGGGSAL

STK24

106

Q9Y6E0
YQWGIMKSLGLSDEE

LARS1

156

Q9P2J5
LAMEVGLVLWVKEYD

MT-ND6

96

P03923
FSIYVMGLVLEWIKN

PSAT1

246

Q9Y617
DDINKFLWMVRIGGS

STT3A

591

P46977
VGEIMWGYKDPLVNL

SCARB1

176

Q8WTV0
LSGYVIMWNKAIELS

STXBP5

176

Q5T5C0
LMSGLDYIKNELQTW

AKAP6

1791

Q13023
NWISYLASKEGMVIA

FAP

556

Q12884
MGYTITLWDLETQGM

SPG11

446

Q96JI7
QEIIAGGDVKYTTWM

XIRP2

431

A4UGR9
KNTDLWIVMEYCGAG

STK3

91

Q13188
IAEAYAELIKQMWSG

USP4

351

Q13107
SGKAADVWSLGVMLY

TRIB1

261

Q96RU8
GQYLVSLIRDKLGWM

SLC37A3

441

Q8NCC5
ETWGGYMAAKVQKLE

REV1

16

Q9UBZ9
SGKAADVWSLGVMLY

TRIB2

231

Q92519
WETVLGQEMYKLLLF

TMC4

476

Q7Z404
MNRYLTTGDLDGWLK

WDR49

431

Q8IV35
VDLEQWYQELMAGLG

PHLDB1

921

Q86UU1
KFTEGSLLDGLYWKM

PKD2

281

Q13563
ADLNIDSWLIKGLMY

ZDHHC17

321

Q8IUH5
ENWAVVKAALVAGMY

YTHDC2

966

Q9H6S0
LQVATFKGWMDIIYA

SCN11A

1251

Q9UI33
YLLKKLTEAMGGGWQ

SWAP70

141

Q9UH65
GGLKAVVWTDAFQMV

SLC5A12

176

Q1EHB4
EYKIMVAALGWATAE

TMEM147

96

Q9BVK8
ASMWDGLGEEQKQVY

TOX

296

O94900
VAEEFGIIMKALWTG

USP8

826

P40818
MAKCYGDLVQELWSG

USP6

581

P35125
GEIKQMWDGGLQDYI

TRPC4

416

Q9UBN4
KTALLEGLEVDQYMW

ZMIZ1

786

Q9ULJ6
DNLYKSDLEWMKGIG

NEB

3381

P20929
KIDGVWNGMIGEVFY

GRIN2D

516

O15399