Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium:chloride symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11	6.98e-07	17	85	4	GO:0015378
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11	1.13e-06	19	85	4	GO:0015373
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4 SLC6A14	1.25e-06	81	85	6	GO:0015370
GeneOntologyMolecularFunction	chloride:monoatomic cation symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11	2.55e-06	23	85	4	GO:0015377
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11	4.26e-06	26	85	4	GO:0015296
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4 SLC6A14	1.18e-05	119	85	6	GO:0015294
GeneOntologyMolecularFunction	symporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4 SLC6A14	4.36e-05	150	85	6	GO:0015293
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4 SLC6A14	9.03e-05	171	85	6	GO:0015081
GeneOntologyMolecularFunction	amino acid:sodium symporter activity	SLC6A8 SLC6A11 SLC6A14	1.24e-04	23	85	3	GO:0005283
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A8 SLC6A11 SLC6A14	2.51e-04	29	85	3	GO:0005416
GeneOntologyMolecularFunction	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A8 SLC6A11	2.66e-04	6	85	2	GO:0005332
GeneOntologyMolecularFunction	beta-glucosidase activity	KL LCTL	2.66e-04	6	85	2	GO:0008422
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC25A4 SLC4A4 SLC6A14	2.69e-04	296	85	7	GO:0015291
GeneOntologyMolecularFunction	modified amino acid transmembrane transporter activity	SLC6A8 SLC25A32 SLC6A14	3.70e-04	33	85	3	GO:0072349
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC6A8 SLC6A11 SLC6A14	4.42e-04	35	85	3	GO:0005343
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4	4.67e-04	151	85	5	GO:0008509
GeneOntologyMolecularFunction	gamma-aminobutyric acid transmembrane transporter activity	SLC6A8 SLC6A11	6.32e-04	9	85	2	GO:0015185
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4	8.20e-04	171	85	5	GO:0015103
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC25A4 SLC4A4 ABCA8 SLC6A14	9.63e-04	477	85	8	GO:0022804
GeneOntologyMolecularFunction	monoamine transmembrane transporter activity	SLC6A3 SLC6A4	1.15e-03	12	85	2	GO:0008504
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC6A8 SLC6A11 SLC25A32 SLC25A4 SLC4A4 SLC6A14	1.57e-03	293	85	6	GO:0008514
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4 SLC6A14	1.80e-03	301	85	6	GO:0022853
GeneOntologyMolecularFunction	monocarboxylate:sodium symporter activity	SLC6A8 SLC6A11	1.81e-03	15	85	2	GO:0140161
GeneOntologyMolecularFunction	glucosidase activity	KL LCTL	1.81e-03	15	85	2	GO:0015926
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11	2.00e-03	125	85	4	GO:0015108
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC25A4 SLC4A4 CHRNA3 SLC6A14 ITPR1	2.04e-03	664	85	9	GO:0008324
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC6A8 SLC6A11	2.92e-03	19	85	2	GO:0015355
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC6A3 SLC6A4	3.57e-03	21	85	2	GO:0005326
GeneOntologyMolecularFunction	amine binding	SLC6A3 SLC6A4	3.57e-03	21	85	2	GO:0043176
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC4A4 SLC6A14 ITPR1	3.68e-03	465	85	7	GO:0046873
GeneOntologyCellularComponent	nuclear inner membrane	LEMD3 FAM169A CBX3 ITPR1	9.77e-05	59	85	4	GO:0005637
Domain	NA_NEUROTRAN_SYMP_2	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC6A14	1.59e-08	18	87	5	PS00754
Domain	SNF	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC6A14	2.16e-08	19	87	5	PF00209
Domain	NA_NEUROTRAN_SYMP_1	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC6A14	2.16e-08	19	87	5	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC6A14	2.16e-08	19	87	5	PS50267
Domain	Na/ntran_symport	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC6A14	2.16e-08	19	87	5	IPR000175
Domain	Glyco_hydro_1_N_CS	KL LCTL	1.28e-04	4	87	2	IPR033132
Domain	Glyco_hydro_1_AS	KL LCTL	1.28e-04	4	87	2	IPR018120
Domain	GLYCOSYL_HYDROL_F1_2	KL LCTL	2.13e-04	5	87	2	PS00653
Domain	GLYCOSYL_HYDROL_F1_1	KL LCTL	2.13e-04	5	87	2	PS00572
Domain	Glyco_hydro_1	KL LCTL	2.13e-04	5	87	2	PF00232
Domain	Glyco_hydro_1	KL LCTL	2.13e-04	5	87	2	IPR001360
Domain	IRF-3	IRF9 IRF5	4.44e-04	7	87	2	PF10401
Domain	Interferon_reg_factor-3	IRF9 IRF5	4.44e-04	7	87	2	IPR019471
Domain	IRF-3	IRF9 IRF5	4.44e-04	7	87	2	SM01243
Domain	IRF	IRF9 IRF5	7.56e-04	9	87	2	SM00348
Domain	Interferon_reg_fact_DNA-bd_dom	IRF9 IRF5	7.56e-04	9	87	2	IPR001346
Domain	IRF	IRF9 IRF5	7.56e-04	9	87	2	PF00605
Domain	IRF_1	IRF9 IRF5	7.56e-04	9	87	2	PS00601
Domain	Interferon_reg_fac_CS	IRF9 IRF5	7.56e-04	9	87	2	IPR019817
Domain	IRF_2	IRF9 IRF5	7.56e-04	9	87	2	PS51507
Domain	Mit_uncoupling	SLC25A32 SLC25A4	1.37e-03	12	87	2	IPR002030
Domain	SMAD_dom-like	IRF9 IRF5	2.47e-03	16	87	2	IPR017855
Domain	-	IRF9 IRF5	2.47e-03	16	87	2	2.60.200.10
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A3 SLC6A11 SLC6A14	7.47e-05	19	62	3	M27362
Pathway	REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS	SLC6A3 SLC6A11 SLC6A14	7.47e-05	19	62	3	MM15107
Pubmed	The repertoire of solute carriers of family 6: identification of new human and rodent genes.	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC6A14	1.82e-09	21	88	5	16125675
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SLC25A32 HBS1L DENND4A SLC25A4 WDR11 CRYBG3 ZBED1 CMTR2 DICER1 ASH2L ITPR1	7.77e-07	650	88	11	38777146
Pubmed	Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice.	SLC6A3 SLC6A4	6.33e-06	2	88	2	19176817
Pubmed	[VNTR polymorphisms of the serotonin transporter and dopamine transporter genes in male opiate addicts].	SLC6A3 SLC6A4	6.33e-06	2	88	2	12173460
Pubmed	Key differences between apoC-III regulation and expression in intestine and liver.	FOXO1 APOC3	6.33e-06	2	88	2	28739253
Pubmed	Treatment-resistant schizophrenia and DAT and SERT polymorphisms.	SLC6A3 SLC6A4	6.33e-06	2	88	2	24680725
Pubmed	Genetic polymorphisms of serotonin and dopamine transporters in mental disorders.	SLC6A3 SLC6A4	6.33e-06	2	88	2	12630565
Pubmed	The effects of the dopamine and serotonin transporter polymorphisms on clinical features and treatment response in geriatric depression: a pilot study.	SLC6A3 SLC6A4	6.33e-06	2	88	2	17621383
Pubmed	A neurochemical approach to valuation sensitivity over gains and losses.	SLC6A3 SLC6A4	6.33e-06	2	88	2	19726478
Pubmed	Serotonergic neurons signal reward and punishment on multiple timescales.	SLC6A3 SLC6A4	6.33e-06	2	88	2	25714923
Pubmed	Upregulation of the creatine transporter Slc6A8 by Klotho.	SLC6A8 KL	6.33e-06	2	88	2	25531216
Pubmed	Midbrain serotonin and striatum dopamine transporter binding in double depression: a one-year follow-up study.	SLC6A3 SLC6A4	6.33e-06	2	88	2	18588943
Pubmed	SERT and DAT availabilities under citalopram treatment in obsessive-compulsive disorder (OCD).	SLC6A3 SLC6A4	6.33e-06	2	88	2	16139170
Pubmed	Serotonin and dopamine transporter genes do not influence depression in Parkinson's disease.	SLC6A3 SLC6A4	6.33e-06	2	88	2	18973248
Pubmed	Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.	SLC6A3 SLC6A4	6.33e-06	2	88	2	11320258
Pubmed	Polymorphisms in genes encoding the serotonin and dopamine pathways in two sisters with metachromatic leukodystrophy.	SLC6A3 SLC6A4	6.33e-06	2	88	2	18831910
Pubmed	Haplotypes of dopamine and serotonin transporter genes are associated with antisocial personality disorder in alcoholics.	SLC6A3 SLC6A4	6.33e-06	2	88	2	20505557
Pubmed	5HTTLPR polymorphism in schizophrenic patients: further support for association with violent suicide attempts.	SLC6A3 SLC6A4	6.33e-06	2	88	2	12707931
Pubmed	FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase.	SLC6A3 FOXO1	6.33e-06	2	88	2	27681312
Pubmed	Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter.	SLC6A3 SLC6A4	6.33e-06	2	88	2	27860344
Pubmed	Association study of the dopamine and serotonin transporter genetic polymorphisms and methamphetamine abuse in Chinese males.	SLC6A3 SLC6A4	6.33e-06	2	88	2	12658362
Pubmed	Genetic polymorphisms of 5-HTT and DAT but not COMT differentially affect verbal and visuospatial working memory functioning.	SLC6A3 SLC6A4	6.33e-06	2	88	2	22454241
Pubmed	Deletion of the Creatine Transporter (Slc6a8) in Dopaminergic Neurons Leads to Hyperactivity in Mice.	SLC6A3 SLC6A8	6.33e-06	2	88	2	31520365
Pubmed	Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding.	SLC6A3 SLC6A4	6.33e-06	2	88	2	34118233
Pubmed	The genetic precursors and the advantageous and disadvantageous sequelae of inhibited temperament: an evolutionary perspective.	SLC6A3 SLC6A4	6.33e-06	2	88	2	23527493
Pubmed	Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice.	SLC6A3 SLC6A4	6.33e-06	2	88	2	9636213
Pubmed	Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence.	SLC6A3 SLC6A4	6.33e-06	2	88	2	15148564
Pubmed	Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands.	SLC6A3 SLC6A4	6.33e-06	2	88	2	27425420
Pubmed	No association of SLC6A3 and SLC6A4 gene polymorphisms with schizophrenia in the Han Chinese population.	SLC6A3 SLC6A4	6.33e-06	2	88	2	25019689
Pubmed	An interaction between the serotonin transporter promoter region and dopamine transporter polymorphisms contributes to harm avoidance and reward dependence traits in normal healthy subjects.	SLC6A3 SLC6A4	6.33e-06	2	88	2	16604301
Pubmed	Imaging genetics for utility of risks over gains and losses.	SLC6A3 SLC6A4	6.33e-06	2	88	2	21801841
Pubmed	The synthesis of bivalent 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)-8-heterobicyclo[3.2.1]octanes as probes for proximal binding sites on the dopamine and serotonin transporters.	SLC6A3 SLC6A4	6.33e-06	2	88	2	18053732
Pubmed	Abnormal expression of dopamine and serotonin transporters associated with the pathophysiologic mechanism of Tourette syndrome.	SLC6A3 SLC6A4	6.33e-06	2	88	2	20739786
Pubmed	Preserved serotonin transporter binding in de novo Parkinson's disease: negative correlation with the dopamine transporter.	SLC6A3 SLC6A4	6.33e-06	2	88	2	20644949
Pubmed	The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and antisocial personality disorder in male heroin-dependent Chinese subjects.	SLC6A3 SLC6A4	6.33e-06	2	88	2	22138326
Pubmed	Klotho, FOXO1 and cytokines associations in patients with coronary artery disease.	FOXO1 KL	6.33e-06	2	88	2	33582500
Pubmed	Brain dopamine and serotonin transporter binding are associated with visual attention bias for food in lean men.	SLC6A3 SLC6A4	6.33e-06	2	88	2	26984412
Pubmed	Differential expression of neuronal dopamine and serotonin transporters DAT and SERT in megakaryocytes and platelets generated from human MEG-01 megakaryoblasts.	SLC6A3 SLC6A4	6.33e-06	2	88	2	22006250
Pubmed	Lower availability of midbrain serotonin transporter between healthy subjects with and without a family history of major depressive disorder - a preliminary two-ligand SPECT study.	SLC6A3 SLC6A4	6.33e-06	2	88	2	24439516
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	HBS1L DENND4A MYPN CRYBG3 DICER1 CEP97	1.58e-05	209	88	6	36779422
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	HBS1L UBAP2 LEMD3 CBX3 ABT1 DICER1 ASH2L ITPR1	1.64e-05	440	88	8	34244565
Pubmed	Adolescent behavioral and neural reward sensitivity: a test of the differential susceptibility theory.	SLC6A3 SLC6A4	1.90e-05	3	88	2	27045841
Pubmed	Association of VNTR polymorphisms in DRD4, 5-HTT and DAT1 genes with obesity.	SLC6A3 SLC6A4	1.90e-05	3	88	2	25687785
Pubmed	SLC6A3 (DAT1) as a Novel Candidate Biomarker Gene for Suicidal Behavior.	SLC6A3 SLC6A4	1.90e-05	3	88	2	34199792
Pubmed	Differential susceptibility to maternal expressed emotion in children with ADHD and their siblings? Investigating plasticity genes, prosocial and antisocial behaviour.	SLC6A3 SLC6A4	1.90e-05	3	88	2	24929324
Pubmed	Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions.	SLC6A3 SLC6A4	1.90e-05	3	88	2	12401330
Pubmed	Serotonin transporter role in identifying similarities between SIDS and idiopathic ALTE.	SLC6A3 SLC6A4	1.90e-05	3	88	2	22711722
Pubmed	Association of IREB2 and CHRNA3/5 polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.	IREB2 CHRNA3	1.90e-05	3	88	2	22914670
Pubmed	IREB2, CHRNA5, CHRNA3, FAM13A & hedgehog interacting protein genes polymorphisms & risk of chronic obstructive pulmonary disease in Tatar population from Russia.	IREB2 CHRNA3	1.90e-05	3	88	2	28474623
Pubmed	Distinct neural mechanisms for the prosocial and rewarding properties of MDMA.	SLC6A3 SLC6A4	1.90e-05	3	88	2	31826983
Pubmed	Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attention deficit/hyperactivity disorder.	SLC6A3 SLC6A4	1.90e-05	3	88	2	19490304
Pubmed	Is the inattentive subtype of ADHD different from the combined/hyperactive subtype?	SLC6A3 SLC6A4	1.90e-05	3	88	2	19767592
Pubmed	Search for association between suicide and 5-HTT, MAOA and DAT polymorphism in Polish males.	SLC6A3 SLC6A4	1.90e-05	3	88	2	21516943
Pubmed	Alternative α-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology.	SLC6A3 DICER1	1.90e-05	3	88	2	23011138
Pubmed	Candidate-gene approach in posttraumatic stress disorder after urban violence: association analysis of the genes encoding serotonin transporter, dopamine transporter, and BDNF.	SLC6A3 SLC6A4	1.90e-05	3	88	2	21491204
Pubmed	FoxO1 regulates leptin-induced mood behavior by targeting tyrosine hydroxylase.	SLC6A3 FOXO1	1.90e-05	3	88	2	30500562
Pubmed	Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice.	SLC6A3 SLC6A4	1.90e-05	3	88	2	19482066
Pubmed	The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter.	SLC6A3 SLC6A4	1.90e-05	3	88	2	12177201
Pubmed	Synaptic mechanism underlying serotonin modulation of transition to cocaine addiction.	SLC6A3 SLC6A4	1.90e-05	3	88	2	34516792
Pubmed	Genetic polymorphisms of alcohol and aldehyde dehydrogenase, dopamine and serotonin transporters in familial and non-familial alcoholism.	SLC6A3 SLC6A4	1.90e-05	3	88	2	16125912
Pubmed	Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5' and 3' flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion.	IRF9 IRF5	1.90e-05	3	88	2	31799619
Pubmed	Understanding the role of the chromosome 15q25.1 in COPD through epigenetics and transcriptomics.	IREB2 CHRNA3	1.90e-05	3	88	2	29422661
Pubmed	Changes in the methylation status of DAT, SERT, and MeCP2 gene promoters in the blood cell in families exposed to alcohol during the periconceptional period.	SLC6A3 SLC6A4	1.90e-05	3	88	2	25656446
Pubmed	Targeted gene expression in dopamine and serotonin neurons of the mouse brain.	SLC6A3 SLC6A4	1.90e-05	3	88	2	15763133
Pubmed	Effect of candidate gene polymorphisms on the course of attention deficit hyperactivity disorder.	SLC6A3 SLC6A4	1.90e-05	3	88	2	19906444
Pubmed	Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency.	IREB2 CHRNA3	1.90e-05	3	88	2	22356581
Pubmed	Genetic determinants of the response to bezafibrate treatment in the lower extremity arterial disease event reduction (LEADER) trial.	FGB APOC3	1.90e-05	3	88	2	12048138
Pubmed	The association of monoamine-related gene polymorphisms with behavioural correlates of response inhibition: A meta-analytic review.	SLC6A3 SLC6A4	1.90e-05	3	88	2	29155230
Pubmed	Genetic polymorphisms of the dopamine and serotonin systems modulate the neurophysiological response to feedback and risk taking in healthy humans.	SLC6A3 SLC6A4	1.90e-05	3	88	2	22810728
Pubmed	Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits.	SLC6A3 SLC6A4	1.90e-05	3	88	2	17392738
Pubmed	A family based association study of DRD4, DAT1, and 5HTT and continuous traits of attention-deficit hyperactivity disorder.	SLC6A3 SLC6A4	1.90e-05	3	88	2	21207241
Pubmed	A novel interferon regulatory factor (IRF), IRF-10, has a unique role in immune defense and is induced by the v-Rel oncoprotein.	IRF9 IRF5	1.90e-05	3	88	2	11997525
Pubmed	Aberrant accumulation of serotonin in dopaminergic neurons.	SLC6A3 SLC6A4	1.90e-05	3	88	2	16638624
Pubmed	PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.	SLC6A3 SLC6A4	1.90e-05	3	88	2	36026451
Pubmed	T cell response kinetics determines neuroinfection outcomes during murine HSV infection.	AVIL IFNLR1	3.79e-05	4	88	2	32161194
Pubmed	CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.	IREB2 CHRNA3	3.79e-05	4	88	2	22461431
Pubmed	The genetic basis for smoking behavior: a systematic review and meta-analysis.	SLC6A3 SLC6A4	3.79e-05	4	88	2	15370155
Pubmed	Molecular characterization of the HIV type 1 subtype C accessory genes vif, vpr, and vpu.	SLC25A4 UNG	3.79e-05	4	88	2	17331040
Pubmed	Personality endophenotypes for bipolar affective disorder: a family-based genetic association analysis.	SLC6A3 SLC6A4	3.79e-05	4	88	2	18826446
Pubmed	Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD.	SLC6A3 SLC6A4	3.79e-05	4	88	2	17948872
Pubmed	Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1.	SLC6A3 SLC6A4	3.79e-05	4	88	2	11343649
Pubmed	[Study of genetic variants in the BDNF, COMT, DAT1 and SERT genes in Colombian children with attention deficit disorder].	SLC6A3 SLC6A4	3.79e-05	4	88	2	29122229
Pubmed	Mest/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset.	SLC6A3 MEST	3.79e-05	4	88	2	28133444
Pubmed	Testing for gene x environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior.	SLC6A3 SLC6A4	3.79e-05	4	88	2	17579368
Pubmed	Serotonin and Dopamine Candidate Gene Variants and Alcohol- and Non-Alcohol-Related Aggression.	SLC6A3 SLC6A4	3.79e-05	4	88	2	26041607
Pubmed	ADHD, CD, and ODD: Systematic review of genetic and environmental risk factors.	SLC6A3 SLC6A4	3.79e-05	4	88	2	29361339
Pubmed	Molecular genetic case-control women investigation from the first Brazilian high-risk study on functional psychosis.	SLC6A3 SLC6A4	3.79e-05	4	88	2	19142409
Pubmed	Genetics of Lesch's typology of alcoholism.	SLC6A3 SLC6A4	3.79e-05	4	88	2	17928119
Pubmed	Candidate genes for COPD: current evidence and research.	IREB2 CHRNA3	3.79e-05	4	88	2	26527870
Pubmed	Genetic influences on quantity of alcohol consumed by adolescents and young adults.	SLC6A3 SLC6A4	3.79e-05	4	88	2	15845322
Pubmed	Non-muscle Mlck is required for β-catenin- and FoxO1-dependent downregulation of Cldn5 in IL-1β-mediated barrier dysfunction in brain endothelial cells.	FOXO1 MYLK	3.79e-05	4	88	2	24522189
Pubmed	Affect-modulated startle reflex and dopamine D4 receptor gene variation.	SLC6A3 SLC6A4	3.79e-05	4	88	2	19818050
Pubmed	Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.	SLC6A3 DOCK3 SLC6A4	4.90e-05	28	88	3	19352218
Pubmed	Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal.	SLC6A3 SLC6A4	6.30e-05	5	88	2	36202097
Pubmed	Antipsychotic-induced extrapyramidal symptoms in patients with schizophrenia: associations with dopamine and serotonin receptor and transporter polymorphisms.	SLC6A3 SLC6A4	6.30e-05	5	88	2	17225991
Pubmed	Effect of genetic polymorphisms on smoking cessation: a trial of bupropion in Korean male smokers.	SLC6A3 SLC6A4	6.30e-05	5	88	2	18197080
Pubmed	Genes implicated in serotonergic and dopaminergic functioning predict BMI categories.	SLC6A3 SLC6A4	6.30e-05	5	88	2	18239643
Pubmed	Physical and genetic maps of the deafwaddler region on distal mouse Chr 6.	SLC6A11 ITPR1	6.30e-05	5	88	2	9615221
Pubmed	Some ADHD polymorphisms (in genes DAT1, DRD2, DRD3, DBH, 5-HTT) in case-control study of 100 subjects 6-10 age.	SLC6A3 SLC6A4	6.30e-05	5	88	2	18404133
Pubmed	Association between the Stin2 VNTR polymorphism of the serotonin transporter gene and treatment outcome in alcohol-dependent patients.	SLC6A3 SLC6A4	6.30e-05	5	88	2	18552399
GeneFamily	Solute carriers	SLC6A3 SLC6A4 SLC6A8 SLC6A11 SLC25A32 SLC25A4 SLC4A4 SLC6A14	2.09e-05	395	54	8	752
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	FOXO1 IRF9 HBS1L PTCH2 ZNF195 SENP5	6.51e-07	155	88	6	a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell	CV-Healthy-3\|CV / Virus stimulation, Condition and Cluster	DOCK3 FOXO1 DENND4A PLEKHO2 CRYBG3 ASH2L	8.13e-07	161	88	6	fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK3 NRXN3 CTSC CRYBG3 SH3RF3 ASH2L	1.51e-06	179	88	6	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FOXO1 FRA10AC1 HBS1L PTCH2 ZNF195 SENP5	1.71e-06	183	88	6	807d64deaf4e50dccf6f831f88578a6d903c1421
ToppCell	droplet-Kidney-nan-18m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A8 KL SAMD9L FOLH1 SLC4A4 ITPR1	1.77e-06	184	88	6	e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FRA10AC1 HBS1L SAMD9L PTCH2 ZNF195 SENP5	1.88e-06	186	88	6	76cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCell	CV-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	DOCK3 DENND4A PLEKHO2 CRYBG3 ASH2L	1.37e-05	154	88	5	26bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYOT MYLK HECTD2 SH3RF3 NMNAT3	1.60e-05	159	88	5	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MEST SLC25A32 KL NRXN3 UNG	1.70e-05	161	88	5	f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC6A3 HSD17B2 NXPH3 IFNLR1	2.03e-05	81	88	4	20796e59cdeb398e7772f4356578d74a33405f71
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXO1 NRXN3 TLE3 ABCA8 CHRNA3	2.15e-05	169	88	5	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A4 PROKR1 PLEKHO2 ESD SNAP23	2.75e-05	178	88	5	63f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A4 PROKR1 PLEKHO2 ESD SNAP23	2.75e-05	178	88	5	82c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCell	PND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC6A4 PROKR1 PLEKHO2 ESD SNAP23	2.75e-05	178	88	5	cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	MEST NRXN3 CTSC SH3RF3 ITPR1	3.48e-05	187	88	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A8 KL FOLH1 SLC4A4 ITPR1	3.48e-05	187	88	5	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CRYBG3 HSD17B2 SH3RF3 ITPR1	3.66e-05	189	88	5	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CRYBG3 HSD17B2 SH3RF3 ITPR1	3.76e-05	190	88	5	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CRYBG3 HSD17B2 SH3RF3 ITPR1	3.76e-05	190	88	5	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	IPF-Epithelial-Goblet\|IPF / Disease state, Lineage and Cell class	NRXN3 ELF3 HSD17B2 SLC4A4 SLC6A14	3.76e-05	190	88	5	e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CRYBG3 HSD17B2 SH3RF3 ITPR1	3.85e-05	191	88	5	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CRYBG3 HSD17B2 SH3RF3 ITPR1	3.85e-05	191	88	5	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYLK CRYBG3 HSD17B2 SH3RF3 ITPR1	3.85e-05	191	88	5	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	IPF-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	SH3PXD2B CTSC HSD17B2 SLC4A4 SLC6A14	3.85e-05	191	88	5	267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	LEMD3 IREB2 CRYBG3 CEP97 MED13	4.05e-05	193	88	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRXN3 MYLK HSD17B2 SH3RF3 ABCA8	4.36e-05	196	88	5	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	(05)_Secretory\|World / shred by cell type by condition	CTSC ELF3 HSD17B2 SLC4A4 SLC6A14	4.36e-05	196	88	5	8032c25b51ef96aeba28cc52686a2bd45213453d
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	SAMD9L NRXN3 MYLK ELF3 ABCA8	4.46e-05	197	88	5	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC25A4 ELF3 SLC4A4 SLC6A14 IGSF3	4.57e-05	198	88	5	19eefd05573fbaed654af52bf0f8a26092b8b229
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC6A8 FOLH1 FGB ELF3 APOC3	4.68e-05	199	88	5	914f66e2b4af323d09fa2340a39cf8051d00a422
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DOCK3 MYLK HECTD2 NMNAT3 ITPR1	4.79e-05	200	88	5	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	MEST NRXN3 ELF3 SLC4A4 IFNLR1	4.79e-05	200	88	5	eac33be484dc443794e66e473f03e98406c2983e
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DOCK3 MYLK HECTD2 NMNAT3 ITPR1	4.79e-05	200	88	5	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
Computational	Genes in the cancer module 162.	SLC6A3 SLC6A4 SLC6A11	1.43e-04	19	59	3	MODULE_162
Computational	Genes in the cancer module 218.	SLC6A3 SLC6A4 SLC6A11	1.68e-04	20	59	3	MODULE_218
Computational	Neighborhood of ERBB2IP	WDR11 NAPG DICER1 ARAP2	4.32e-04	65	59	4	GCM_ERBB2IP
Drug	naphthalene-1,5-disulfonate	SLC6A3 SLC6A4 LARS1	1.11e-06	6	88	3	CID000006666
Drug	FP-CIT	SLC6A3 SLC6A4 CTSC	1.20e-05	12	88	3	CID000122197
Drug	Sertraline	SLC6A3 SLC6A4	1.48e-05	2	88	2	DB01104
Drug	methylcyanoformate	SLC6A3 SLC6A4	1.48e-05	2	88	2	CID000028660
Drug	N-Nor-cit	SLC6A3 SLC6A4	1.48e-05	2	88	2	CID000131993
Drug	dichloropane	SLC6A3 SLC6A4	1.48e-05	2	88	2	CID000127024
Drug	2beta-carbomethoxy-3beta-(4-iodophenyl)tropane	SLC6A3 SLC6A4	1.48e-05	2	88	2	ctd:C069723
Drug	benzhydryl ether	SLC6A3 SLC6A4	1.48e-05	2	88	2	CID000011323
Drug	glutamate	SLC6A3 SLC6A4 SLC6A11 IRF9 SLC25A32 MYLK FOLH1 LARS1 IREB2 SLC4A4 CHRNA3 NMNAT3 DHX8 ITPR1	1.84e-05	962	88	14	CID000000611
Drug	Prednisolut	ESD AVIL LARS1	3.65e-05	17	88	3	CID000004897
Drug	D-161 compound	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C532102
Drug	Mazindol	SLC6A3 SLC6A4	4.42e-05	3	88	2	DB00579
Drug	Methylphenidate	SLC6A3 SLC6A4	4.42e-05	3	88	2	DB00422
Drug	Duloxetine	SLC6A3 SLC6A4	4.42e-05	3	88	2	DB00476
Drug	2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C569113
Drug	Venlafaxine	SLC6A3 SLC6A4	4.42e-05	3	88	2	DB00285
Drug	4-fluoroamphetamine	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C040639
Drug	Sibutramine	SLC6A3 SLC6A4	4.42e-05	3	88	2	DB01105
Drug	RTI-219	SLC6A3 SLC6A4	4.42e-05	3	88	2	CID010524711
Drug	2-(4-bromo-2,5-dimethoxyphenyl)ethylamine	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C079321
Drug	1-phenyl-2-(1-pyrrolidinyl)-1-pentanone	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C000592273
Drug	difluoropine	SLC6A3 SLC6A4	4.42e-05	3	88	2	CID000190851
Drug	Dexmethylphenidate	SLC6A3 SLC6A4	4.42e-05	3	88	2	DB06701
Drug	2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C000595926
Drug	1,4-diazabicyclo[3.3.1]nonane	SLC6A3 SLC6A4	4.42e-05	3	88	2	CID015140257
Drug	99mTc-NC100697	SLC6A3 SLC6A4	4.42e-05	3	88	2	CID016066474
Drug	5-(2-aminopropyl)benzofuran	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C000608250
Drug	4-methoxymethamphetamine	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C060169
Drug	2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine	SLC6A3 SLC6A4	4.42e-05	3	88	2	ctd:C554181
Drug	Fluorescent Dyes	SLC6A3 SLC6A4	8.82e-05	4	88	2	ctd:D005456
Drug	Chlorpheniramine	SLC6A3 SLC6A4	8.82e-05	4	88	2	DB01114
Drug	bicyclo[3.2.1]octane	SLC6A3 SLC6A4	8.82e-05	4	88	2	CID000260716
Drug	benzylpiperidine	SLC6A3 SLC6A4	8.82e-05	4	88	2	CID000076190
Drug	O 526	SLC6A3 SLC6A4	8.82e-05	4	88	2	CID003025846
Drug	Biogenic Monoamines	SLC6A3 SLC6A4	8.82e-05	4	88	2	ctd:D015306
Drug	4-(4-Chlorophenyl)piperidine	SLC6A3 SLC6A4	8.82e-05	4	88	2	CID001203613
Drug	butriptyline	SLC6A3 SLC6A4	8.82e-05	4	88	2	CID000021771
Drug	indatraline	SLC6A3 SLC6A4	8.82e-05	4	88	2	ctd:C418119
Drug	Indomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A	WSCD1 DICER1 CHRNA3 NXPH3 ITPR1 SENP5	1.11e-04	195	88	6	5468_UP
Drug	homopiperazine	SLC6A3 SLC6A4 MYLK	1.21e-04	25	88	3	CID000068163
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; PC3; HT_HG-U133A	PLEKHO2 PTCH2 FGB DICER1 CHRNA3 ITPR1	1.24e-04	199	88	6	6699_UP
Drug	vinyl sulfoxide	SLC6A3 SLC6A4	1.47e-04	5	88	2	CID000014217
Drug	Phentermine	SLC6A3 SLC6A4	1.47e-04	5	88	2	DB00191
Drug	[11c]afe	SLC6A3 SLC6A4	1.47e-04	5	88	2	CID005732447
Drug	[11c]afa	SLC6A3 SLC6A4	1.47e-04	5	88	2	CID005352128
Drug	[11c]afm	SLC6A3 SLC6A4	1.47e-04	5	88	2	CID005352125
Drug	Mazindol	SLC6A3 SLC6A4	1.47e-04	5	88	2	ctd:D008454
Drug	Nomifensine	SLC6A3 SLC6A4	1.47e-04	5	88	2	ctd:D009627
Disease	attention deficit hyperactivity disorder (is_implicated_in)	SLC6A3 DOCK3 SLC6A4	2.63e-05	20	86	3	DOID:1094 (is_implicated_in)
Disease	nicotine dependence (is_implicated_in)	SLC6A3 CHRNA3	1.25e-04	6	86	2	DOID:0050742 (is_implicated_in)
Disease	mortality	NRXN3 SLC25A4 DICER1 ARAP2 DHX8	1.55e-04	173	86	5	EFO_0004352
Disease	coronary artery disease (is_implicated_in)	KL MYLK FGB APOC3	2.13e-04	100	86	4	DOID:3393 (is_implicated_in)
Disease	Memory Loss	SLC6A3 SLC6A4 KL	2.71e-04	43	86	3	C0751295
Disease	Age-Related Memory Disorders	SLC6A3 SLC6A4 KL	2.71e-04	43	86	3	C0751292
Disease	Memory Disorder, Spatial	SLC6A3 SLC6A4 KL	2.71e-04	43	86	3	C0751294
Disease	Memory Disorder, Semantic	SLC6A3 SLC6A4 KL	2.71e-04	43	86	3	C0751293
Disease	Memory Disorders	SLC6A3 SLC6A4 KL	2.71e-04	43	86	3	C0025261
Disease	Memory impairment	SLC6A3 SLC6A4 KL	2.90e-04	44	86	3	C0233794
Disease	Glaucoma	MYLK SLC4A4	2.98e-04	9	86	2	C0017601
Disease	overall survival	CTSC CMTR2	2.98e-04	9	86	2	EFO_0000638
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	SLC6A3 CHRNA3	5.44e-04	12	86	2	C1861063
Disease	amyotrophic lateral sclerosis, age at onset	NRXN3 ARAP2	8.60e-04	15	86	2	EFO_0004847, MONDO_0004976
Disease	N-acetylmethionine measurement	DOCK3 ITPR1	8.60e-04	15	86	2	EFO_0021427
Disease	anemia (implicated_via_orthology)	IREB2 SLC4A4	8.60e-04	15	86	2	DOID:2355 (implicated_via_orthology)
Disease	lung small cell carcinoma (is_marker_for)	APOC3 CHRNA3	9.81e-04	16	86	2	DOID:5409 (is_marker_for)
Disease	Alcohol abuse	SLC6A3 SLC6A4 CHRNA3	1.00e-03	67	86	3	C0085762
Disease	glaucoma (implicated_via_orthology)	SH3PXD2B NMNAT3	1.11e-03	17	86	2	DOID:1686 (implicated_via_orthology)
Disease	Alcoholic Intoxication, Chronic	SLC6A3 SLC6A4 NRXN3 UBAP2 CHRNA3	1.14e-03	268	86	5	C0001973
Disease	Amphetamine-Related Disorders	SLC6A3 SLC6A4 SH3RF3	1.39e-03	75	86	3	C0236733
Disease	Amphetamine Abuse	SLC6A3 SLC6A4 SH3RF3	1.39e-03	75	86	3	C0236807
Disease	Amphetamine Addiction	SLC6A3 SLC6A4 SH3RF3	1.39e-03	75	86	3	C0236804
Disease	chronic kidney disease (is_marker_for)	KL APOC3	1.54e-03	20	86	2	DOID:784 (is_marker_for)
Disease	hemoglobin measurement, mean corpuscular hemoglobin	HBS1L DENND4A	1.87e-03	22	86	2	EFO_0004509, EFO_0004527
Disease	Anhedonia	SLC6A3 SLC6A4	2.22e-03	24	86	2	C0178417
Disease	Attention deficit hyperactivity disorder	SLC6A3 MED13	2.22e-03	24	86	2	C1263846
Disease	venous thromboembolism	LEMD3 FOLH1 TLE3 FGB NCR2 ASH2L	2.28e-03	460	86	6	EFO_0004286

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESWKKHLSGEFGKPY	UNG	96	P13051
FLLWGSYAQKKGSAI	UNG	251	P13051
KAFSGYLGTDQSKWK	ESD	186	P10768
DQSGTKIYVWKGKGA	AVIL	286	O75366
GSEKAAKRGPSKSWY	ASCL5	21	Q7RTU5
VNGKVEYFLKWKGFT	CBX3	41	Q13185
LEKGKYKCFFDWGGS	CRYBG3	2631	Q68DQ2
KFGSWSYDKAKIDLV	CHRNA3	176	P32297
EALSWKDKVAKGYFN	CMTR2	451	Q8IYT2
VYKFGKNSSGWKEEE	ELF3	351	P78545
FYGASAKKVKSGWLD	ARAP2	476	Q8WZ64
YPNLDFGWKKSIDSK	DICER1	1091	Q9UPY3
LGYDKFSYSWRSKKG	ASH2L	451	Q9UBL3
AGKGVAEKASKWYSR	DENND4A	1326	Q7Z401
GKKYGSGNSRDWAAK	IREB2	846	P48200
KFLGLSKKYWEDGSR	GDAP1L1	281	Q96MZ0
KAGKASFAYAWVLDE	HBS1L	301	Q9Y450
KAFKALHGSWFDGKL	LEMD3	846	Q9Y2U8
ITKTWRKEGVGGFYK	SLC25A32	266	Q9H2D1
GLAYSGKKSGDWTMK	PSKH2	206	Q96QS6
TRKVWAGKFFKAYSA	MYLK	1486	Q15746
EAYGKKEWKHFLSDT	NT5DC1	101	Q5TFE4
GSLYEKKGWCKEASA	NCR2	46	O95944
SGDLVFAKLKGYAHW	HDGFL1	11	Q5TGJ6
LKYEVAFWKEGAGNK	IFNLR1	156	Q8IU57
YSAQKQFWKAAKPGA	ITPR1	66	Q14643
EGFEGKSLYESWTKK	FOLH1	486	Q04609
KVKSSGDWKAVHDFY	HECTD2	141	Q5U5R9
GGKKKGSKWNTRESY	EBNA1BP2	251	Q99848
DKKEGLKSWEVNFGY	FRA10AC1	181	Q70Z53
DWKGDKVKAHYGGFT	FGB	346	P02675
EKLTIGKISKYWSGF	PLSCR5	211	A0PG75
KAIKDGANIKGYTSW	LCTL	441	Q6UWM7
FAKKGWTYDSVKTPI	FAM47B	611	Q8NA70
NTIFKAWAKETGKYT	IRF5	61	Q13568
GKKRSYTKDYTEGWV	ABT1	96	Q9ULW3
YFKDKGDSNSSAGWK	FOXO1	196	Q12778
FAVAWYSLRTKAGGK	IGSF3	986	O75054
SEKKGVWGVFYKAAV	TMEM167B	36	Q9NRX6
KIIHYFNKGKSWEFG	DOCK3	1296	Q8IZD9
KESLKAEWLYSQGKG	CEP97	241	Q8IW35
WFAFFKYKEEGSKVT	CTSC	101	P53634
KILWKKGEAIGFYSV	FAM169A	146	Q9Y6X4
AWAIFKGKYKEGDTG	IRF9	61	Q00978
GWFVSGTTKRDDAKY	KL	416	Q9UEF7
WLTYKGKKEGSTKGE	KIAA1210	51	Q9ULL0
KFWTLAGSALLYKKG	EML6	1531	Q6ZMW3
GTVFCKYKKSSGQLW	HSD17B2	21	P37059
HSWKSSGKFFTYKGL	MEST	41	Q5EB52
PEWKKHAFGGNKASY	DHX8	536	Q14562
VKKIFGWGDFYSNIK	NXPH3	96	O95157
WGKGYSRKAAALEFL	STIP1	71	P31948
SKAGLSTVYKWNSKG	LGI2	346	Q8N0V4
KAAAKAGSSKYQWGI	LARS1	146	Q9P2J5
KSKEEHFYRGGKVSW	SAMD9L	681	Q8IVG5
GGYKAHAPKWESKDF	NRXN3	441	Q9HDB5
GKSWDLNKICYKSGV	PTCH2	151	Q9Y6C5
SGWAFIKYVLSDKEK	GPR108	351	Q9NPR9
KNFESGKAYKTTWGD	SNAP23	91	O00161
RKDGYVWSGKKLSWS	SOCS4	26	Q8WXH5
WKGVKSTGKIVYFTA	SLC6A8	251	P48029
DSATKKLIGEWKQFY	MED13	226	Q9UHV7
AGSSLFLKKKWGIGY	ABCA8	696	O94911
IAKDEGAKAFFKGAW	SLC25A4	261	P12235
GFSSLKDYWSTVKDK	APOC3	66	P02656
WKASYNGGKSSADLD	PROKR1	361	Q8TCW9
AFSEKWNTGFGGFKK	SENP5	16	Q96HI0
NKSSYGLKGAWKNSV	UBAP2	241	Q5T6F2
KGAKKSQGLWSDYSD	ZNF250	86	P15622
KTGFLKWKPDYDSAA	NAPG	21	Q99747
FVHKKREDGWYKGTL	SH3RF3	851	Q8TEJ3
KEGWAPASYLKKNSG	SH3PXD2B	266	A1X283
LYFSLWKGVKTSGKV	SLC6A3	251	Q01959
FCIWKGTKSTGKVVY	SLC6A11	241	P48066
LKFAYCGKWFVSTGK	TLE3	706	Q04726
FYKSFGGEKWKTNVL	TM9SF2	421	Q99805
WAFLSKKECSKYGGN	SLC4A4	666	Q9Y6R1
KKSSGGLLGFWKDRY	PLEKHO2	26	Q8TD55
GTLYNKGFKGEKDHW	WSCD1	386	Q658N2
AKSKVWKYFGFDTNA	ZBED1	21	O96006
ADTGTKLWKKSYADN	WDR11	146	Q9BZH6
WSSLTLLGSYKGKKC	RPP14	86	O95059
IYFSIWKGVKTSGKV	SLC6A4	266	P31645
AWGGLVALSSYNKFK	SLC6A14	326	Q9UN76
LAGEKLSKCETWYKG	ZNF195	376	O14628
ESSEYYWKSGKVGKL	ZBBX	61	A8MT70
KDVNKKDAGWYTVSA	MYOT	411	Q9UBF9
AKKSDAGWYTLSAKN	MYPN	1236	Q86TC9
YIKDHGLYTKGSTWK	NMNAT3	226	Q96T66