Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of muscle

OBSCN MYOM2 DMD MYBPC1

2.25e-0543774GO:0008307
GeneOntologyMolecularFunctioncell adhesion molecule binding

CIB2 PI4KA OBSCN APC EVPL BCAM DMD ARHGAP18 ITGAM IQGAP1

9.85e-055997710GO:0050839
GeneOntologyBiologicalProcessprotein localization to centrosome

CEP350 APC PCM1 KIAA0753

1.33e-0538794GO:0071539
GeneOntologyBiologicalProcessprotein localization to microtubule organizing center

CEP350 APC PCM1 KIAA0753

1.48e-0539794GO:1905508
GeneOntologyBiologicalProcessprotein autophosphorylation

TAOK2 PTK2B CAMKK2 IGF1R OBSCN TRIM24 IQGAP1

2.71e-05228797GO:0046777
GeneOntologyBiologicalProcesssupramolecular fiber organization

PTK2B SH3PXD2B GMFG OBSCN APC MYOM2 COLGALT1 ARHGAP18 CAMSAP2 GBA2 PCM1 IQGAP1 MYBPC1

6.53e-059577913GO:0097435
GeneOntologyBiologicalProcessmRNA transcription

HIPK3 THRA ZBTB1 STAT3

6.75e-0557794GO:0009299
GeneOntologyBiologicalProcessprotein localization to microtubule cytoskeleton

CEP350 APC PCM1 KIAA0753

7.73e-0559794GO:0072698
GeneOntologyBiologicalProcesspeptidyl-tyrosine autophosphorylation

PTK2B IGF1R IQGAP1

7.90e-0522793GO:0038083
GeneOntologyBiologicalProcessprotein localization to cytoskeleton

CEP350 APC PCM1 KIAA0753

1.00e-0463794GO:0044380
GeneOntologyBiologicalProcesscalcium ion homeostasis

PTK2B CIB2 ATP7B CD19 DMD TRIM24 ATP2B1 CNGA1

1.21e-04389798GO:0055074
GeneOntologyCellularComponentanchoring junction

PTK2B SH3PXD2B CIB2 ATP7B LMO7 PI4KA OBSCN APC RPS16 EVPL DMD PRX IQGAP1

6.08e-059767813GO:0070161
GeneOntologyCellularComponentmyosin filament

OBSCN MYOM2 MYBPC1

1.08e-0425783GO:0032982
GeneOntologyCellularComponentM band

OBSCN MYOM2 MYBPC1

2.08e-0431783GO:0031430
Domain-

LMO7 DMD CAMSAP2 IQGAP1

2.21e-04717841.10.418.10
DomainCH

LMO7 DMD CAMSAP2 IQGAP1

2.46e-0473784PS50021
DomainCH-domain

LMO7 DMD CAMSAP2 IQGAP1

2.73e-0475784IPR001715
DomainKinase-like_dom

TAOK2 HIPK3 PTK2B CAMKK2 IGF1R PI4KA OBSCN DMD TRRAP

4.20e-04542789IPR011009
Domain-

PI4KA TRRAP

1.99e-03167821.10.1070.11
DomainPI3Kc

PI4KA TRRAP

1.99e-0316782SM00146
DomainPI3/4_kinase_cat_dom

PI4KA TRRAP

2.52e-0318782IPR000403
DomainPI3_PI4_kinase

PI4KA TRRAP

2.52e-0318782PF00454
DomainPI3_4_KINASE_3

PI4KA TRRAP

2.52e-0318782PS50290
DomainPI3_4_KINASE_1

PI4KA TRRAP

2.52e-0318782PS00915
DomainPI3_4_KINASE_2

PI4KA TRRAP

2.52e-0318782PS00916
DomainCH

LMO7 DMD IQGAP1

2.54e-0365783SM00033
DomainCH

LMO7 DMD IQGAP1

3.14e-0370783PF00307
Domainfn3

IGF1R OBSCN MYOM2 MYBPC1

4.73e-03162784PF00041
DomainProtein_kinase_ATP_BS

TAOK2 HIPK3 PTK2B CAMKK2 IGF1R OBSCN

5.05e-03379786IPR017441
DomainTUDOR

TDRKH ARID4B

5.65e-0327782SM00333
DomainSpectrin_repeat

EVPL DMD

6.50e-0329782IPR002017
DomainTudor

TDRKH ARID4B

6.94e-0330782IPR002999
DomainFN3

IGF1R OBSCN MYOM2 MYBPC1

7.52e-03185784SM00060
DomainPROTEIN_KINASE_TYR

PTK2B IGF1R OBSCN

7.80e-0397783PS00109
DomainTyr_kinase_AS

PTK2B IGF1R OBSCN

7.80e-0397783IPR008266
DomainSpectrin/alpha-actinin

EVPL DMD

7.87e-0332782IPR018159
Domain-

ATP7B ATP2B1

7.87e-03327823.40.1110.10
Domain-

ATP7B ATP2B1

7.87e-03327822.70.150.10
DomainSPEC

EVPL DMD

7.87e-0332782SM00150
PathwayREACTOME_STAT3_NUCLEAR_EVENTS_DOWNSTREAM_OF_ALK_SIGNALING

SIN3A STAT3 DNMT1

1.01e-0511573M42523
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CEP350 FSIP2 NHSL1 PTK2B STOX2 SH3PXD2B IGF1R LMO7 PI4KA APC NAV1 RABGEF1 CAMSAP2 ATP2B1 PCM1 STAT3 DNMT1 KIAA0753

8.63e-13861801836931259
Pubmed

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.

IGF1R APC STAT3

1.17e-08380326364612
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

CEP350 ADSL LMO7 BOP1 EIF3B CAMSAP2 PCM1 KIAA0753

1.22e-0725180829778605
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CEP350 EPC2 ADSL ARID4B GTF3C2 PI4KA CHAF1A NAV1 MRRF PCM1 KIAA0753

2.70e-07645801125281560
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TAOK2 STOX2 SH3PXD2B PI4KA G3BP2 APC NAV1 RABGEF1 CAMSAP2 ZBTB1 PCM1 DNMT1 IQGAP1

2.95e-07963801328671696
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

EPC2 KIF27 ARID4B GTF3C2 PI4KA CHAF1A SIN3A TRIM24 TRRAP ATP2B1 STAT3 NOVA2

6.02e-07857801225609649
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SLC6A1 NHSL1 PTK2B LMO7 PI4KA TTC21A G3BP2 APC NAV1 RPS16 DMD CAMSAP2 ATP2B1 PCM1 IQGAP1

8.17e-071431801537142655
Pubmed

A PAK5-DNPEP-USP4 axis dictates breast cancer growth and metastasis.

DMD PRX IQGAP1

9.75e-07980331219614
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TAOK2 NHSL1 SH3PXD2B IGF1R PCNX3 BTBD7 PI4KA OBSCN NAV1 DISP2 BCAM TRRAP GBA2

1.37e-061105801335748872
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

CEP350 ZNHIT6 PCM1 KIAA0753

1.80e-063880436674791
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

EPC2 ARID4B SIN3A TRRAP

2.72e-064280416387653
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CEP350 NHSL1 EPC2 IGF1R ZNHIT6 ADSL CHAF1A APC TRIM24 KIAA0753

4.13e-06689801036543142
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ADSL KIF27 GTF3C2 PI4KA G3BP2 CHAF1A RPS16 BOP1 EIF3B COLGALT1 ATP2B1 DNMT1 IQGAP1 MYBPC1

4.23e-061425801430948266
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CEP350 NAV1 TRIM24 CAMSAP2 PCM1 KIAA0753

4.39e-0618480632908313
Pubmed

Suppression of intestinal neoplasia by DNA hypomethylation.

APC DNMT1

5.23e-0628027537636
Pubmed

Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice.

APC DNMT1

5.23e-06280211888894
Pubmed

JAK/STAT3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3.

IGF1R STAT3

5.23e-06280215998644
Pubmed

Regulation of Id gene expression by type I insulin-like growth factor: roles of Stat3 and the tyrosine 950 residue of the receptor.

IGF1R STAT3

5.23e-06280211463827
Pubmed

Insulin-like growth factor 1 receptor and p38 mitogen-activated protein kinase signals inversely regulate signal transducer and activator of transcription 3 activity to control human dental pulp stem cell quiescence, propagation, and differentiation.

IGF1R STAT3

5.23e-06280224266654
Pubmed

Tripartite Motif-containing Protein 11 Silencing Inhibits Proliferation and Glycolysis and Promotes Apoptosis of Esophageal Squamous Cell Carcinoma Cells by Inactivating Signal Transduction and Activation of Transcription Factor 3/c-Myc Signaling.

TRIM11 STAT3

5.23e-06280238780271
Pubmed

Suppressive effect of global DNA hypomethylation on gastric carcinogenesis.

APC DNMT1

5.23e-06280220622006
Pubmed

Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 promotes cell proliferation and migration by upregulating DNMT1 via STAT3 activation.

STAT3 DNMT1

5.23e-06280224675762
Pubmed

Stat3 is a negative regulator of intestinal tumor progression in Apc(Min) mice.

APC STAT3

5.23e-06280219962983
Pubmed

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes.

STAT3 DNMT1

5.23e-06280216861352
Pubmed

Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells.

CD19 TRRAP

5.23e-06280224675885
Pubmed

Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation.

APC DNMT1

5.23e-06280225939752
Pubmed

Co-ordinated expression of lymphoid and myeloid specific transcription factors during B-1b cell differentiation into mononuclear phagocytes in vitro.

CD19 ITGAM

5.23e-06280218710404
Pubmed

Critical role for Stat3 in T-dependent terminal differentiation of IgG B cells.

CD19 STAT3

5.23e-06280216223771
Pubmed

Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.

APC DNMT1

5.23e-06280212538347
Pubmed

Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway.

APC DNMT1

5.23e-06280212538344
Pubmed

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target.

CD19 STAT3

5.23e-06280215895073
Pubmed

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.

APC DNMT1

5.23e-06280216174748
Pubmed

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses.

APC STAT3

5.23e-06280219701202
Pubmed

Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis.

ARID4B SIN3A

5.23e-06280222693453
Pubmed

ApcMin/+ mouse model of colon cancer: gene expression profiling in tumors.

APC DNMT1

5.23e-06280215486983
Pubmed

Impact of CUX2 on the female mouse liver transcriptome: activation of female-biased genes and repression of male-biased genes.

CUX2 TRIM24

5.23e-06280222966202
Pubmed

Regulation of Id1 protein expression in mouse embryo fibroblasts by the type 1 insulin-like growth factor receptor.

IGF1R STAT3

5.23e-06280212061821
Pubmed

STAT3 deficiency in B cells exacerbates uveitis by promoting expansion of pathogenic lymphocytes and suppressing regulatory B cells (Bregs) and Tregs.

CD19 STAT3

5.23e-06280233004854
Pubmed

Age-associated alteration of gene expression patterns in mouse oocytes.

CHAF1A SIN3A TRIM24 DNMT1

5.97e-065180415317747
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

CEP350 ATP7B LMO7 G3BP2 EIF3B COLGALT1 ATP2B1 PCM1 STAT3 DNMT1

9.07e-06754801033060197
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

EPC2 TDRKH ZNHIT6 THRA ATP7B ARID4B CHAF1A SIN3A TRIM24 TRRAP PCM1 NOVA2

9.07e-061116801231753913
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

FSIP2 ARID4B GTF3C2 CHAF1A BOP1 SIN3A TRIM24 TRRAP DNMT1

1.11e-0560880936089195
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

ARID4B PI4KA APC BOP1 MRRF PCM1 DNMT1 IQGAP1

1.40e-0547580831040226
Pubmed

Interplay between SIN3A and STAT3 mediates chromatin conformational changes and GFAP expression during cellular differentiation.

SIN3A STAT3

1.57e-05380221779366
Pubmed

ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis.

IGF1R STAT3

1.57e-05380232029900
Pubmed

Sphingomyelin maintains the cutaneous barrier via regulation of the STAT3 pathway.

SGMS1 STAT3

1.57e-05380235230716
Pubmed

Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice.

APC STAT3

1.57e-05380222461519
Pubmed

TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma.

TRIM24 STAT3

1.57e-05380229129908
Pubmed

STAT3 signaling controls satellite cell expansion and skeletal muscle repair.

DMD STAT3

1.57e-05380225194572
Pubmed

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

CD19 DNMT1

1.57e-05380219801979
Pubmed

The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation.

PTK2B ITGAM

1.57e-05380232693110
Pubmed

Stat3 is indispensable for damage-induced crypt regeneration but not for Wnt-driven intestinal tumorigenesis.

APC STAT3

1.57e-05380230156908
Pubmed

The MDA-9/Syntenin/IGF1R/STAT3 Axis Directs Prostate Cancer Invasion.

IGF1R STAT3

1.57e-05380229572229
Pubmed

Beta-glucosidase 2 knockout mice with increased glucosylceramide show impaired liver regeneration.

GBA2 STAT3

1.57e-05380222764777
Pubmed

Suppressor of cytokine signalling-2 limits IGF1R-mediated regulation of epithelial-mesenchymal transition in lung adenocarcinoma.

IGF1R STAT3

1.57e-05380229559623
Pubmed

Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.

APC DNMT1

1.57e-05380221362628
Pubmed

Knockout of STAT3 in skeletal muscle does not prevent high-fat diet-induced insulin resistance.

DMD STAT3

1.57e-05380226266089
Pubmed

Multifaceted roles for STAT3 in gammaherpesvirus latency revealed through in vivo B cell knockout models.

CD19 STAT3

1.57e-05380238170993
Pubmed

Metastatic cells can escape the proapoptotic effects of TNF-α through increased autocrine IL-6/STAT3 signaling.

IGF1R STAT3

1.57e-05380222194466
Pubmed

Signal transducer and activator of transcription 3 (STAT3) protein suppresses adenoma-to-carcinoma transition in Apcmin/+ mice via regulation of Snail-1 (SNAI) protein stability.

APC STAT3

1.57e-05380222496368
Pubmed

Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization.

PTK2B STAT3

1.57e-05380227210483
Pubmed

MLKL inhibits intestinal tumorigenesis by suppressing STAT3 signaling pathway.

APC STAT3

1.57e-05380233767595
Pubmed

A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.

CD19 STAT3

1.57e-05380229400710
Pubmed

Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma.

STAT3 DNMT1

1.57e-05380228627705
Pubmed

STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus.

CD19 STAT3

1.57e-05380227183592
Pubmed

STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration.

DMD STAT3

1.57e-05380227524611
Pubmed

Correlation between the expression of DNMT1, and GSTP1 and APC, and the methylation status of GSTP1 and APC in association with their clinical significance in prostate cancer.

APC DNMT1

1.57e-05380225738352
Pubmed

Control of myeloid-specific integrin alpha Mbeta 2 (CD11b/CD18) expression by cytokines is regulated by Stat3-dependent activation of PU.1.

ITGAM STAT3

1.57e-05380211889125
Pubmed

Ovarian cancer: Stat3, RhoA and IGF-IR as therapeutic targets.

IGF1R STAT3

1.57e-05380222120672
Pubmed

Intestinal Epithelial Deletion of Sphk1 Prevents Colitis-Associated Cancer Development by Inhibition of Epithelial STAT3 Activation.

APC STAT3

1.57e-05380231776862
Pubmed

Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice.

CD19 ATP2B1

1.57e-05380233098669
Pubmed

Regulation of CD11b by HIF-1α and the STAT3 signaling pathway contributes to the immunosuppressive function of B cells in inflammatory bowel disease.

ITGAM STAT3

1.57e-05380231063937
Pubmed

JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia.

APC STAT3

1.57e-05380222669242
Pubmed

A human MAP kinase interactome.

CEP350 HIPK3 ARID4B CHAF1A APC NAV1 EVPL DMD

1.65e-0548680820936779
Pubmed

Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.

EPC2 SIN3A TRRAP

2.01e-052380314966270
Pubmed

IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3.

IGF1R THRA

3.13e-05480228007906
Pubmed

Hospicells promote upregulation of the ATP-binding cassette genes by insulin-like growth factor-I via the JAK2/STAT3 signaling pathway in an ovarian cancer cell line.

IGF1R STAT3

3.13e-05480223857432
Pubmed

Sex differences in the relationship of IL-6 signaling to cancer cachexia progression.

APC STAT3

3.13e-05480225555992
Pubmed

RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.

IGF1R STAT3

3.13e-05480216382134
Pubmed

Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation.

PTK2B STAT3

3.13e-05480214963038
Pubmed

STAT3-mediated epigenetic silencing of FOXP3 in LADA T cells is regulated through HDAC5 and DNMT1.

STAT3 DNMT1

3.13e-05480229223407
Pubmed

IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis.

IGF1R STAT3

3.13e-05480228223169
Pubmed

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.

IGF1R APC

3.13e-05480212595570
Pubmed

Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration.

APC IQGAP1

3.13e-05480215572129
Pubmed

MRTF-A and STAT3 promote MDA-MB-231 cell migration via hypermethylating BRSM1.

STAT3 DNMT1

3.13e-05480225854163
Pubmed

Activation of IGF1R by DARPP-32 promotes STAT3 signaling in gastric cancer cells.

IGF1R STAT3

3.13e-05480231235784
Pubmed

Dnmt1N/+ reduces the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong synergy with the modifier of Min 1(AKR) resistance allele.

APC DNMT1

3.13e-05480210919675
Pubmed

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

STAT3 DNMT1

3.13e-05480215870198
Pubmed

Integrin CD11b Negatively Regulates B Cell Receptor Signaling to Shape Humoral Response during Immunization and Autoimmunity.

CD19 ITGAM

3.13e-05480234470858
Pubmed

Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice.

APC STAT3

3.13e-05480221204268
Pubmed

FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.

PTK2B APC

3.13e-05480226274564
Pubmed

Thyroid hormone receptor and IGF1/IGFR systems: possible relations in the human heart.

IGF1R THRA

3.13e-05480217560756
Pubmed

Little skate genome provides insights into genetic programs essential for limb-based locomotion.

WSB1 CIB2 THRA

3.29e-052780336288084
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SH3PXD2B GTF3C2 LMO7 SIN3A TRRAP PCM1 STAT3 DNMT1

3.92e-0554980838280479
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

NHSL1 SH3PXD2B LMO7 PI4KA EVPL ARHGAP18 ATP2B1 IQGAP1

4.80e-0556580825468996
Pubmed

Infection-induced type I interferons activate CD11b on B-1 cells for subsequent lymph node accumulation.

CD19 ITGAM

5.20e-05580226612263
Pubmed

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.

APC STAT3

5.20e-05580226880802
Pubmed

Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway.

DMD STAT3

5.20e-05580222606352
Pubmed

Interleukin 6 induces cell proliferation of clear cell renal cell carcinoma by suppressing hepaCAM via the STAT3-dependent up-regulation of DNMT1 or DNMT3b.

STAT3 DNMT1

5.20e-05580228093267
Pubmed

Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy.

DMD PRX

5.20e-05580211430802
InteractionHDAC4 interactions

ADSL ARID4B LMO7 PI4KA APC NAV1 RPS16 BOP1 SIN3A EIF3B CAMSAP2 MRRF PCM1 DNMT1 IQGAP1

1.68e-077447915int:HDAC4
InteractionYWHAG interactions

TAOK2 CEP350 NHSL1 STOX2 IGF1R LMO7 PI4KA CHAF1A APC NAV1 RABGEF1 TRRAP CAMSAP2 PCM1 STAT3 DNMT1 IQGAP1 KIAA0753

1.18e-0612487918int:YWHAG
InteractionSEPTIN10 interactions

CEP350 TRIM11 IGF1R ADSL APC PCM1 KIAA0753

1.55e-06144797int:SEPTIN10
InteractionCEP135 interactions

CEP350 ADSL LMO7 CHAF1A APC NAV1 PCM1 KIAA0753

1.13e-05272798int:CEP135
InteractionSFN interactions

CEP350 STOX2 CAMKK2 IGF1R LMO7 G3BP2 APC NAV1 RPS16 RABGEF1 CAMSAP2 STAT3

1.52e-056927912int:SFN
InteractionYWHAH interactions

CEP350 NHSL1 STOX2 SH3PXD2B THRA LMO7 PI4KA APC NAV1 RABGEF1 CAMSAP2 PCM1 DNMT1 IQGAP1 KIAA0753

2.12e-0511027915int:YWHAH
InteractionCEP128 interactions

CEP350 ADSL LMO7 APC NAV1 CAMSAP2 PCM1 KIAA0753

2.13e-05297798int:CEP128
InteractionTRIM36 interactions

CEP350 SH3PXD2B APC NAV1 CAMSAP2 KIAA0753

2.17e-05144796int:TRIM36
InteractionMAPRE3 interactions

TAOK2 CEP350 SH3PXD2B LMO7 APC NAV1 CAMSAP2

3.32e-05230797int:MAPRE3
InteractionPRNP interactions

TAOK2 CEP350 SLC6A1 NHSL1 EPC2 IGF1R ZNHIT6 ADSL CHAF1A APC DMD TRIM24 ATP2B1 IQGAP1 KIAA0753

3.76e-0511587915int:PRNP
InteractionMBD2 interactions

PTK2B ARID4B CHAF1A APC SIN3A DNMT1

4.07e-05161796int:MBD2
InteractionTOP3B interactions

TAOK2 NHSL1 TDRKH SH3PXD2B IGF1R PCNX3 BTBD7 PI4KA G3BP2 OBSCN NAV1 RPS16 DISP2 BCAM TRRAP GBA2 IQGAP1

4.45e-0514707917int:TOP3B
InteractionRPS27 interactions

FSIP2 IGF1R G3BP2 APC RPS16 EIF3B TMEM41B ZBTB1

6.29e-05346798int:RPS27
InteractionKDM1A interactions

CEP350 ZNHIT6 GTF3C2 CHAF1A APC NAV1 SIN3A TRIM24 TRRAP ZBTB1 PCM1 STAT3 DNMT1

6.96e-059417913int:KDM1A
InteractionGOLGA1 interactions

CEP350 ATP7B APC NAV1 PCM1 KIAA0753

8.29e-05183796int:GOLGA1
InteractionYWHAQ interactions

CEP350 NHSL1 STOX2 IGF1R THRA LMO7 CHAF1A APC NAV1 RABGEF1 CAMSAP2 PCM1 DNMT1 IQGAP1

1.02e-0411187914int:YWHAQ
InteractionCREBBP interactions

HIPK3 THRA CHAF1A APC SIN3A TRIM24 TRRAP CAMSAP2 STAT3 IQGAP1

1.14e-045997910int:CREBBP
InteractionTHAP11 interactions

CAMKK2 RPS16 RABGEF1 SIN3A TRRAP

1.18e-04122795int:THAP11
InteractionEED interactions

PTK2B EPC2 IGF1R ARID4B OBSCN RPS16 BOP1 RABGEF1 SIN3A EIF3B COLGALT1 TRRAP PCM1 STAT3 DNMT1 IQGAP1

1.29e-0414457916int:EED
InteractionYWHAB interactions

CEP350 NHSL1 STOX2 IGF1R LMO7 CHAF1A APC NAV1 RABGEF1 TRRAP CAMSAP2 PCM1 IQGAP1

1.47e-0410147913int:YWHAB
InteractionAGBL4 interactions

CEP350 ZNHIT6 PCM1 KIAA0753

1.65e-0470794int:AGBL4
Cytoband19q13.2

GMFG BCAM PRX FAM98C

2.01e-0416480419q13.2
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYOM2 MYBPC1

2.16e-048512658
GeneFamilyFibronectin type III domain containing

IGF1R OBSCN MYOM2 MYBPC1

1.07e-03160514555
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_UP

ADSL GTF3C2 PI4KA CHAF1A RPS16 BOP1 TPGS2 EIF3B TRRAP ATP2B1 PCM1 DNMT1

3.34e-076128012M4772
CoexpressionGSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP

TDRKH IGF1R THRA GMFG COLGALT1 ATP2B1

3.16e-05197806M8166
CoexpressionGSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN

CAMKK2 ZNHIT6 SGMS1 G3BP2 GMFG CNGA1

3.35e-05199806M9170
CoexpressionGSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP

PTK2B SGMS1 ARID4B CD19 BTBD7 ATP2B1

3.44e-05200806M3251
CoexpressionRIZKI_TUMOR_INVASIVENESS_3D_UP

TAOK2 HIPK3 IGF1R PI4KA APC DMD

4.40e-05209806M17026
CoexpressionPANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP

STOX2 MATN2 GMFG FGD1 NAV1

5.73e-05134805M2185
CoexpressionPANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP

STOX2 MATN2 GMFG FGD1 NAV1

6.36e-05137805MM886
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 CAMKK2 CD19 ATP2B1 PCM1 IQGAP1

1.04e-061858067adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTK2B SH3PXD2B COLGALT1 ARHGAP18 ITGAM ATP2B1

1.59e-06199806379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellmLN-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

WSB1 SH3PXD2B ADSL ARHGAP18 STAT3 IQGAP1

1.64e-06200806e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

LMO7 OBSCN CHST9 MYOM2 DMD

2.76e-061228051cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellRV|World / Chamber and Cluster_Paper

STOX2 OBSCN NAV1 CHST9 MYOM2

1.88e-05181805bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 CD19 ATP2B1 PCM1 IQGAP1

1.93e-05182805f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B TRIM11 CD19 GMFG RPS16

1.93e-051828056946ab8d91fb8dce5af065f57a13659b8d97ed5c
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 CEP350 LMO7 APC BCAM

2.14e-051868050ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LMO7 APC ITGAM ATP2B1 IQGAP1

2.20e-05187805b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3PXD2B CIB2 MATN2 COLGALT1 IQGAP1

2.31e-05189805b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

LMO7 OBSCN CHST9 MYOM2 DMD

2.31e-051898055e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

LMO7 OBSCN CHST9 MYOM2 DMD

2.37e-05190805de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3PXD2B CIB2 MATN2 COLGALT1 IQGAP1

2.37e-05190805da58227565ad6a690828dd8554dd3670222f8582
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 SGMS1 MATN2 COLGALT1 ITGAM

2.37e-051908051d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellASK440-Epithelial-Secretory|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

FSIP2 ATP7B LMO7 CHST9 BCAM

2.55e-0519380550e98d91697c7af6a3de39e52edde6dd2b67b512
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIB2 MATN2 CHAF1A COLGALT1 DNMT1

2.62e-05194805effd38e51062b225ecabc7e1c50154e65495d559
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

IGF1R LMO7 OBSCN MYOM2 DMD

2.62e-0519480589812fb164065041357bb37a3c2d87028ec3de4e
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

CIB2 G3BP2 NAV1 RPS16 DMD

2.62e-05194805d21461682fa755f588afe073abb6a777f339c4cc
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NHSL1 LMO7 EVPL BCAM DMD

2.68e-051958050e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCellwk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NHSL1 LMO7 EVPL BCAM DMD

2.75e-05196805e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCell11.5-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

LMO7 EVPL CHST9 BCAM DMD

2.82e-05197805e671af1b69566d97afe97f1a959a07b6f4c05620
ToppCell10x3'2.3-week_14-16-Myeloid_monocytic-monocyte-MOP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HIPK3 PTK2B RPS16 EIF3B COLGALT1

2.82e-05197805cbfe62cd4c38ae3c893b869e8af8defb9777df25
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

SH3PXD2B COLGALT1 ARHGAP18 ITGAM ATP2B1

2.89e-051988059bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCellnormal_Lung-Endothelial_cells-Tip-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

LMO7 GMFG BCAM ARHGAP18 PRX

2.96e-0519980572c96a5954dfcfbfee8f095984ce1f5249d9a679
ToppCelltumor_Lung-Endothelial_cells-Tip-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

THRA LMO7 GMFG ARHGAP18 PRX

2.96e-0519980580c8641cfd84436eadf2234f1313749e2f73331f
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 STOX2 MATN2 BCAM IQGAP1

2.96e-05199805174f6013af6eafa577f84205a62927f2b367fda3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm|6m / Sample Type, Dataset, Time_group, and Cell type.

HIPK3 LMO7 MYOM2 DMD MYBPC1

3.03e-052008050f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCellCOVID-19|World / Disease, condition lineage and cell class

ARID4B G3BP2 ZBTB1 STAT3 IQGAP1

3.03e-052008057dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PTK2B ATP2B1 CNGA1 TMEM200A

4.80e-051118041847dde68d349114286bc3317be6339666df4aa2
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THRA TTC21A SPINDOC DNMT1

1.25e-04142804c3a5a80f78704d34db5df85d6e3e8fc84ff24268
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

PTK2B LMO7 MATN2 ATP2B1

1.32e-04144804e2a2f260f5ebaaef46248d199c407a15ce9d024a
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

KIF27 OBSCN EVPL DISP2

1.97e-04160804a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

SLC6A1 TDRKH CUX2 CAMSAP2

2.02e-041618045f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A1 STOX2 OBSCN NAV1

2.02e-04161804441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

KIF27 OBSCN EVPL DISP2

2.02e-0416180482196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CUX2 ATP7B CAMSAP2 FAM98C

2.12e-04163804d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TAOK2 TDRKH SPINDOC PRX

2.17e-04164804d2218d50e0e2d19f919dcb460b3840687c082810
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM11 CD19 CHAF1A GMFG

2.27e-0416680416d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM11 CD19 CHAF1A GMFG

2.27e-0416680408d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B DISP2 CHST9 TMEM200A

2.32e-041678043dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B DISP2 CHST9 TMEM200A

2.32e-0416780495b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B DISP2 CHST9 TMEM200A

2.32e-041678049480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCelldroplet-Heart-nan-18m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 RABGEF1 MRRF NOVA2

2.38e-041688042201ae834b53cbdc085f8f02607fa5b5bd911268
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL1 NAV1 PRX NOVA2

2.43e-04169804987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellfacs-Marrow-KLS-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 GALNT12 MYOM2 CAMSAP2

2.72e-041748040cf40ce9d9ad926c4909665aaa224694b5d970cb
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PTK2B CAMKK2 KIF27 ATP2B1

2.78e-04175804ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PTK2B CAMKK2 KIF27 ATP2B1

2.78e-0417580421f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell(2)_NK/T-(23)_CD4+_T_cell-(232)_CD4+/CD45RA+_Naive_T_cell|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)

IGF1R LMO7 OBSCN RPS16

2.78e-04175804fc40fda0fb9954cb0970c6ac71f6d6df7d27dc5c
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CUX2 CHST9 DMD ARHGAP18

2.84e-041768041e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 BTBD7 DMD PCM1

2.84e-04176804749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGF1R LMO7 PDZD7 BCAM

2.84e-04176804f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellControl-Lymphoid-pDC|Control / Condition, Lineage and Cell class

CUX2 CIB2 CHAF1A DMD

2.84e-041768045de16ff65476bde8b23322a44e11412e14f1bafe
ToppCellControl-Myeloid-pDC|Control / Disease group,lineage and cell class (2021.01.30)

CUX2 CIB2 CHAF1A DMD

2.84e-04176804baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK2B CUX2 CAMKK2 TRIM11

2.84e-04176804c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

HIPK3 FSIP2 GALNT12 CAMSAP2

2.84e-041768047a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NHSL1 NAV1 PRX NOVA2

2.84e-0417680464e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK2B CUX2 CAMKK2 CHST9

2.90e-041778048b003ed7887479c3a010ef37dd981b748256bda7
ToppCellPND28-Immune|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD19 GMFG RPS16 ITGAM

2.90e-04177804087bcda36589e3554e6f2c170542a4be7833cfd2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DISP2 CHST9 CNGA1 TMEM200A

2.90e-0417780443dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID4B LMO7 BTBD7 PCM1

2.96e-0417880401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTK2B CUX2 TMEM200A MYBPC1

3.09e-041808045e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GMFG ARHGAP18 PRX NOVA2

3.09e-041808047d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIB2 OBSCN MYOM2 MYBPC1

3.09e-04180804cea62fc006d68c3815c88bf17ec2617d7e41c3d2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R SGMS1 BCAM IQGAP1

3.22e-04182804e6a734fb29105093d4cbfc3d0619a825b66da034
ToppCelldroplet-Lung-3m-Hematologic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTK2B GMFG RPS16 ITGAM

3.22e-041828046c06ee60f0f1bb2b8a97d978ef5a59d671f043a3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R SGMS1 BCAM IQGAP1

3.22e-04182804ccc313ecc0bfd8e2c6bb83a565b427b2310485ec
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

SLC6A1 LMO7 CHST9 BCAM

3.22e-04182804caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCelldroplet-Marrow-nan-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 CAMKK2 PCM1 DNMT1

3.22e-04182804bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R SGMS1 BCAM IQGAP1

3.22e-04182804b9f758961fb4a586ae86fa0b25edb8ce4616d644
ToppCelldroplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B CIB2 MATN2 COLGALT1

3.29e-04183804ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Late_airway_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LMO7 EVPL BCAM DMD

3.29e-041838040cea883a8a79fc58abcb26b08bf5db9d3d60f7d4
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LMO7 EVPL GALNT12 CHST9

3.36e-04184804fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3PXD2B CIB2 MATN2 COLGALT1

3.36e-0418480415ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 APC PCM1 IQGAP1

3.36e-041848041154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3PXD2B CIB2 MATN2 COLGALT1

3.36e-041848048fa30789c9d583188667cf375d2218e392dd40bc
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

LMO7 OBSCN MYOM2 DMD

3.36e-04184804ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CD19 GMFG RPS16

3.36e-041848048fa7aa2a954f66576ada56670b4e1bb122864761
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3PXD2B CIB2 MATN2 COLGALT1

3.36e-04184804bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CD19 GMFG RPS16

3.36e-04184804b5fbfcf8516c2dc20dffc36803692505a63f1297
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B CIB2 MATN2 COLGALT1

3.36e-041848043261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SH3PXD2B CIB2 MATN2 COLGALT1

3.43e-041858044bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Aerocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TDRKH BCAM PRX NOVA2

3.43e-041858047b3d30a54bec66ca6b0209c86448f4fff97ed75c
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A1 MATN2 TMEM200A PRX

3.43e-04185804554c5d812197fbf66bf279fcc953277e926ade15
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

LMO7 OBSCN MYOM2 DMD

3.43e-041858046baccb26f999145e51b91d94315bf8d4655bef31
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMD CAMSAP2 ATP2B1 STAT3

3.43e-04185804eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCelldroplet-Limb_Muscle-nan-3m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CD19 GMFG RPS16

3.43e-04185804a01d25a5642337cfcdef5fcd189b3150a5fad911
ToppCelldroplet-Liver-Npc-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAOK2 CHAF1A BCAM SPINDOC

3.50e-0418680475258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GMFG BCAM ARHGAP18 PRX

3.50e-04186804dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GMFG BCAM ARHGAP18 PRX

3.50e-04186804080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R SGMS1 BCAM IQGAP1

3.57e-041878043e25c15fa29f8c738044914e8b3420d5713f18d9
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B CIB2 MATN2 COLGALT1

3.57e-04187804f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CD19 GMFG RPS16

3.57e-04187804890e80d0ee3cd548e4c1d0fa917c1d4080a06c13
ToppCelldroplet-Limb_Muscle-nan-24m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B CD19 GMFG RPS16

3.57e-0418780467dc43f17f4b75c6a841bca5e2755fa895b390ab
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B CIB2 MATN2 COLGALT1

3.57e-04187804f20e7a1751694390f535ffb27b97e887220f8695
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R SGMS1 BCAM IQGAP1

3.57e-04187804965584ee44669a72866a20ddf7f657bc5a7f7a8b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGF1R SGMS1 BCAM IQGAP1

3.57e-04187804a7ef179e6561e17cafae10e1843bf82ac3ae0c89
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B SGMS1 CD19 IQGAP1

3.57e-04187804b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

NAV1 ARHGAP18 PRX NOVA2

3.57e-04187804fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTK2B SGMS1 CD19 IQGAP1

3.57e-041878043ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

LMO7 OBSCN CHST9 MYOM2

3.57e-0418780478cdcf8bc141d3b155c3c8af908431fc419c4d08
DiseaseAnemia, Macrocytic

THRA APC

6.90e-062782C0002886
Diseaseprostate cancer (is_marker_for)

PTK2B IGF1R ADSL FGD1 DNMT1

5.99e-05156785DOID:10283 (is_marker_for)
DiseaseSchizophrenia

SLC6A1 CAMKK2 PI4KA APC NAV1 ARHGAP18 ITGAM TRRAP PCM1 DNMT1

1.09e-048837810C0036341
DiseaseGrowth Disorders

SH3PXD2B IGF1R FGD1

1.19e-0436783C0018273
Diseaseneutropenia (implicated_via_orthology)

ITGAM STAT3

1.44e-047782DOID:1227 (implicated_via_orthology)
DiseaseChildhood Medulloblastoma

APC STAT3 DNMT1

2.03e-0443783C0278510
DiseaseMelanotic medulloblastoma

APC STAT3 DNMT1

2.03e-0443783C1275668
DiseaseMedullomyoblastoma

APC STAT3 DNMT1

2.03e-0443783C0205833
DiseaseDesmoplastic Medulloblastoma

APC STAT3 DNMT1

2.03e-0443783C0751291
DiseaseAdult Medulloblastoma

APC STAT3 DNMT1

2.03e-0443783C0278876
Diseaseneuroblastoma (is_implicated_in)

IGF1R CHAF1A

3.06e-0410782DOID:769 (is_implicated_in)
DiseaseMedulloblastoma

APC STAT3 DNMT1

3.18e-0450783C0025149
DiseaseColorectal Carcinoma

ZNHIT6 ATP7B LMO7 OBSCN APC GALNT12 DMD CAMSAP2

5.34e-04702788C0009402
Diseasetransient cerebral ischemia (implicated_via_orthology)

SIN3A ITGAM STAT3

6.59e-0464783DOID:224 (implicated_via_orthology)
Diseaserenal cell carcinoma (is_implicated_in)

THRA APC STAT3

8.21e-0469783DOID:4450 (is_implicated_in)
DiseaseEye Abnormalities

SH3PXD2B APC

9.14e-0417782C0015393
Diseasehypertrophic cardiomyopathy (is_marker_for)

IGF1R DNMT1

9.14e-0417782DOID:11984 (is_marker_for)
DiseaseCongenital hernia of foramen of Morgagni

IGF1R STAT3

1.15e-0319782C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF1R STAT3

1.15e-0319782C0265700
Diseaseheel bone mineral density, urate measurement

MYOM2 ARHGAP18 PCM1 IQGAP1

1.40e-03182784EFO_0004531, EFO_0009270
DiseaseCongenital diaphragmatic hernia

IGF1R STAT3

1.40e-0321782C0235833
DiseaseOvarian Serous Adenocarcinoma

TRIM24 TRRAP

1.68e-0323782C1335177
DiseaseAdenocarcinoma of large intestine

CAMKK2 APC TRRAP

2.13e-0396783C1319315
Diseasehearing impairment

SH3PXD2B CIB2 DNMT1

2.26e-0398783C1384666
Diseasehypertension, COVID-19

CUX2 ATP2B1

2.32e-0327782EFO_0000537, MONDO_0100096

Protein segments in the cluster

PeptideGeneStartEntry
QRKMRVNVDPEDLIP

BOP1

376

Q14137
IKEIKMEEERNIIPR

ARID4B

436

Q4LE39
MEEERNIIPREEKPI

ARID4B

441

Q4LE39
REKKESMVIPVPEAE

EPC2

66

Q52LR7
IFRMREKQVPVDVVE

EIF3B

546

P55884
EMRQKEIPRVLEQLE

DNMT1

901

P26358
PMELVQRGDIVKVVP

ATP7B

821

P35670
EAIQEVEMLPRPPKV

DMD

246

P11532
KVPMVVLQDILAVRP

CHAF1A

236

Q13111
VPEEIREMVAPVLKS

CUX2

56

O14529
QESAVRPRRMVEPLE

DISP2

256

A7MBM2
PRDRDDIVKTVIEPM

ATP2B1

626

P20020
KTLINAEDPPMVVVR

IQGAP1

856

P46940
RGKVPPERVEKIMDQ

RABGEF1

196

Q9UJ41
PLRENVPRVIMIVTD

MATN2

156

O00339
VRPADLTRVIMPLEQ

MAGEA11

101

P43364
ELKMELPERQPRFVV

GMFG

56

O60234
LPPVERDVVKTIVDM

FSIP2

4686

Q5CZC0
FVPRPERKRRDVMQV

IGF1R

731

P08069
EDVKVVPPSMRRIRA

NHSL1

271

Q5SYE7
MEEIPVKVAVRIRPL

KIF27

1

Q86VH2
LRLPEMEPLVPRVKE

PCM1

1906

Q15154
VRRVPLEIPEEQTLM

PCNX3

736

Q9H6A9
RNKAREPMELVVRVP

PDZD7

936

Q9H5P4
KRPPTVQEKIIMEEV

EVPL

1451

Q92817
ALRDTPKVMEPILQI

PI4KA

626

P42356
LPDLEKDDMIVRRIP

LMO7

561

Q8WWI1
EKVREIPQAMTKPEV

NOVA2

101

Q9UNW9
ADLKPENIMLVDPVR

HIPK3

321

Q9H422
VEIKLVEQGPRRVEM

OBSCN

5086

Q5VST9
VMAPVKRRNVIPHDI

GBA2

581

Q9HCG7
MEVRPEEPLVVKVEE

CD19

16

P15391
DSEPVQRILIAKPIM

G3BP2

381

Q9UN86
QRPEEIPMDLTVVKQ

ZNHIT6

66

Q9NWK9
AEETIVPLMAEPKRV

CEP350

2891

Q5VT06
PERERIRMQSPVDVI

GALNT12

291

Q8IXK2
VVANEIPVPRLLIMK

BTBD7

641

Q9P203
MRAVLIPIREVLTPE

FAM98C

256

Q17RN3
MLDKNPESRIVVPEI

CAMKK2

426

Q96RR4
MVVVPVDVEKEDVRI

PTK2B

26

Q14289
RMQVEHPEKAVPRVR

COLGALT1

471

Q8NBJ5
AEVRLSVPPLVEVMR

BCAM

31

P50895
EDMDTVIKPRPQVVK

CAMSAP2

1246

Q08AD1
DPETKIRIQRPQVMT

MUC17

4476

Q685J3
KEEVTLRVVVRMPPQ

NAV1

1416

Q8NEY1
RIQVMVQPSEDIVRP

SLC6A1

566

P30531
KEDPMDRLLVPQVAI

TMEM200A

436

Q86VY9
PKVIERRIRQELPFM

ADSL

366

P30566
KDREIPVPLMERQES

FGD1

351

P98174
PIPQVTREHREMLVK

MRRF

181

Q96E11
LIKVNGRPLEMIEPR

RPS16

31

P62249
PAIQLRLKEPMDVDV

SIN3A

941

Q96ST3
VLRERPPTVIMDLIQ

TAOK2

281

Q9UL54
LDLQVIRVRMEEPPA

SPINDOC

321

Q9BUA3
IRVRMEEPPAVSLLQ

SPINDOC

326

Q9BUA3
PVLRVKAIMEFNPRE

ITGAM

616

P11215
VDRKDPAVNIMLERP

KIAA0753

836

Q2KHM9
IQKDVELRIMPPVQE

APC

1516

P25054
QMPELRENPFKERIV

CIB2

61

O75838
LRPVPRIMSTEKIQE

CHST9

61

Q7L1S5
PNVIVPDIEKEIRRM

CNGA1

16

P29973
MALVQALVPREREPK

C11orf40

1

Q8WZ69
KVPVVMLEPIRIKQE

TRIM24

711

O15164
DVKLQPPEVVPMELR

TRIM11

256

Q96F44
EMRVPQEAVKLIIGR

TDRKH

56

Q9Y2W6
VKEMVRILRTVPFLP

MRPL10

161

Q7Z7H8
IPREVEMEIIRRINP

STOX2

306

Q9P2F5
MPPRRSIVEVKVLDV

SH3PXD2B

1

A1X283
DPIVQHRPMLEERIV

STAT3

296

P40763
KVPEMAVPEVRLPEV

PRX

506

Q9BXM0
MAVPEVRLPEVQLPK

PRX

536

Q9BXM0
EVRLPEVQLPKVPEM

PRX

566

Q9BXM0
QLPKVSEIRLPEMQV

PRX

746

Q9BXM0
VMISVVHERVPPKEV

SGMS1

151

Q86VZ5
QSRILKRVPLEQPEM

TTC21A

866

Q8NDW8
EQDQRKVPGMRIPLI

ARHGAP18

331

Q8N392
EVTIIEKPPAERHMI

TPGS2

36

Q68CL5
ERKRIIIKMEPEDIP

ZBTB1

321

Q9Y2K1
VIPARLPKMEVRAEE

nan

66

A8MUI8
VIPARLPKMEVRAEE

nan

66

A8MUA0
DMALNPINVKRPVER

GTF3C2

736

Q8WUA4
RKEEMIRSLQQRPEP

THRA

146

P10827
EQVIPARLPKMEVRA

nan

101

Q5PR19
RRVMPTQEVQELPIP

WSB1

396

Q9Y6I7
PQLSEEERVNMKVPR

TMEM41B

76

Q5BJD5
VPRVVAVSPQMRLVE

TRRAP

3571

Q9Y4A5
LDEQVIPTRLPKMEV

nan

61

A6NL46
MLVTPDLKRVQPRAE

MYOM2

301

P54296
FVREPPIMVTKQLED

MYBPC1

336

Q00872