Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

CHRD SLIT1

6.99e-0429272GO:0043395
GeneOntologyMolecularFunctiongrowth factor activity

VEGFC CCN2 JAG1

1.60e-03173273GO:0008083
GeneOntologyMolecularFunctionintegrin binding

CCN2 ADAM8 ITGB6

1.66e-03175273GO:0005178
GeneOntologyMolecularFunctionproteoglycan binding

CHRD SLIT1

2.16e-0351272GO:0043394
GeneOntologyMolecularFunctionheparin binding

CHRD CCN2 SLIT1

2.16e-03192273GO:0008201
GeneOntologyMolecularFunctioncalcium ion binding

PLSCR3 CELSR3 ADAM8 JAG1 SLIT1

2.98e-03749275GO:0005509
GeneOntologyCellularComponentpresynaptic active zone membrane

NTNG2 LRFN1 CELSR3

1.22e-0478263GO:0048787
GeneOntologyCellularComponentpresynaptic active zone

NTNG2 LRFN1 CELSR3

6.97e-04141263GO:0048786
DomainVWC

KCP CHRD CCN2 CRIM1 SSPOP JAG1

1.35e-1138276SM00214
DomainVWF_dom

KCP CHRD CCN2 CRIM1 SSPOP JAG1

2.55e-1142276IPR001007
DomainVWFC_1

KCP CHRD CCN2 CRIM1 SSPOP

1.56e-0936275PS01208
DomainVWFC_2

KCP CHRD CCN2 CRIM1 SSPOP

2.07e-0938275PS50184
DomainVWC_out

KCP CRIM1 SSPOP JAG1

1.32e-0819274SM00215
DomainEGF_1

NTNG2 CELSR3 ADAM8 SSPOP ITGB6 JAG1 SLIT1

5.73e-08255277PS00022
DomainVWC

KCP CHRD CCN2 CRIM1

6.92e-0828274PF00093
DomainEGF_2

NTNG2 CELSR3 ADAM8 SSPOP ITGB6 JAG1 SLIT1

7.45e-08265277PS01186
DomainEGF_3

NTNG2 CELSR3 ADAM8 SSPOP JAG1 SLIT1

8.83e-07235276PS50026
DomainEGF_extracell

NTNG2 ADAM8 ITGB6 JAG1

1.60e-0660274IPR013111
DomainEGF_2

NTNG2 ADAM8 ITGB6 JAG1

1.60e-0660274PF07974
DomainEGF-like_CS

NTNG2 CELSR3 ADAM8 ITGB6 JAG1 SLIT1

1.63e-06261276IPR013032
DomainCTCK_1

CCN2 SSPOP SLIT1

2.17e-0618273PS01185
DomainCys_knot_C

CCN2 SSPOP SLIT1

6.07e-0625273IPR006207
DomainCTCK_2

CCN2 SSPOP SLIT1

6.07e-0625273PS01225
DomainEGF

NTNG2 CELSR3 ADAM8 JAG1 SLIT1

1.95e-05235275SM00181
DomainEGF-like_dom

NTNG2 CELSR3 ADAM8 JAG1 SLIT1

2.57e-05249275IPR000742
DomainEGF

NTNG2 CELSR3 JAG1 SLIT1

3.07e-05126274PF00008
DomainGrowth_fac_rcpt_

CCN2 CRIM1 JAG1 SLIT1

7.08e-05156274IPR009030
DomainUnchr_dom_Cys-rich

KCP SSPOP

1.55e-0413272IPR014853
DomainC8

KCP SSPOP

1.55e-0413272SM00832
DomainTIL_dom

KCP SSPOP

1.81e-0414272IPR002919
DomainVWFD

KCP SSPOP

2.39e-0416272PS51233
DomainVWD

KCP SSPOP

2.39e-0416272SM00216
DomainVWF_type-D

KCP SSPOP

2.39e-0416272IPR001846
DomainVWD

KCP SSPOP

2.39e-0416272PF00094
DomainIB

CCN2 CRIM1

3.04e-0418272SM00121
DomainIGFBP_N_2

CCN2 CRIM1

3.76e-0420272PS51323
DomainIGFBP-like

CCN2 CRIM1

3.76e-0420272IPR000867
DomainIGFBP

CCN2 CRIM1

3.76e-0420272PF00219
DomainCT

CCN2 SLIT1

4.57e-0422272SM00041
DomainEGF-type_Asp/Asn_hydroxyl_site

CELSR3 JAG1 SLIT1

4.71e-04106273IPR000152
DomainEGF_CA

CELSR3 JAG1 SLIT1

7.09e-04122273SM00179
DomainhEGF

JAG1 SLIT1

7.43e-0428272PF12661
DomainEGF-like_Ca-bd_dom

CELSR3 JAG1 SLIT1

7.44e-04124273IPR001881
DomainEGF_LAM_2

NTNG2 CELSR3

8.54e-0430272PS50027
DomainEGF_LAM_1

NTNG2 CELSR3

8.54e-0430272PS01248
DomainLaminin_EGF

NTNG2 CELSR3

1.16e-0335272PF00053
DomainEGF_Lam

NTNG2 CELSR3

1.16e-0335272SM00180
DomainLAM_G_DOMAIN

CELSR3 SLIT1

1.37e-0338272PS50025
DomainLaminin_EGF

NTNG2 CELSR3

1.37e-0338272IPR002049
DomainLaminin_G_2

CELSR3 SLIT1

1.52e-0340272PF02210
DomainLamG

CELSR3 SLIT1

1.83e-0344272SM00282
DomainLaminin_G

CELSR3 SLIT1

3.16e-0358272IPR001791
DomainTSP_1

CCN2 SSPOP

3.72e-0363272PF00090
DomainZinc_finger_PHD-type_CS

NFXL1 SP110

3.96e-0365272IPR019786
DomainTSP1

CCN2 SSPOP

3.96e-0365272SM00209
DomainTSP1_rpt

CCN2 SSPOP

3.96e-0365272IPR000884
DomainTSP1

CCN2 SSPOP

3.96e-0365272PS50092
DomainPHD

KMT2D SP110

5.23e-0375272PF00628
DomainZnf_PHD-finger

KMT2D SP110

5.79e-0379272IPR019787
Pubmed

Connective tissue growth factor regulates fibrosis-associated renal lymphangiogenesis.

VEGFC CCN2

5.80e-07227228545716
Pubmed

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.

CCN2 ADAM8 JAG1

7.05e-064827335247391
Pubmed

Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β.

CCN2 ITGB6

1.22e-05727222885106
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR3 SLIT1

2.08e-0592729693030
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

CCN2 CELSR3 JAG1 SLIT1

4.08e-0525127429031500
Pubmed

YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling.

VEGFC CCN2

4.50e-051327233060128
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR3 SSPOP

6.06e-051527220473291
Pubmed

SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.

CCN2 CRIM1

6.06e-051527218215621
Pubmed

Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

VEGFC CCN2

6.06e-051527228684544
Pubmed

Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac.

VEGFC JAG1

6.92e-051627221352545
Pubmed

ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death.

CCN2 ITGB6

7.84e-051727238816193
Pubmed

The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development.

VEGFC JAG1

8.81e-051827216678147
Pubmed

Regulation of developmental lymphangiogenesis by Syk(+) leukocytes.

VEGFC JAG1

8.81e-051827220230750
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

CHRD KCNQ2 C1QTNF1 NTNG2 CRIM1 SERINC1

9.04e-0598527612975309
Pubmed

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.

JAG1 SLIT1

9.84e-051927225691540
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

JAG1 SLIT1

1.09e-042027229961574
Pubmed

Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling.

CELSR3 JAG1

1.21e-042127226939553
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

NTNG2 CRIM1 SLIT1

1.27e-0412627316284245
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

ITGB6 JAG1

1.45e-042327219897741
Pubmed

Hierarchical organization of cortical and thalamic connectivity.

CCN2 NTNG2

1.59e-042427231666704
Pubmed

Conditionals by inversion provide a universal method for the generation of conditional alleles.

CHRD CCN2

2.01e-042727223918385
Pubmed

YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct.

CCN2 JAG1

2.33e-042927232520726
Pubmed

Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.

CCN2 CRIM1

2.33e-042927220615956
Pubmed

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".

VEGFC CCN2 ADAM8

3.19e-0417227320628624
Pubmed

Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.

CDCA7 SP110

3.21e-043427225391964
Pubmed

Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.

CCN2 SLIT1

3.21e-043427230504829
Pubmed

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.

VEGFC CCN2

3.60e-043627219411759
Pubmed

The developing mouse coronal suture at single-cell resolution.

CCN2 JAG1

3.80e-043727234376651
Pubmed

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.

KMT2D JAG1

4.01e-043827227930960
Pubmed

YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.

CCN2 ITGB6

4.45e-044027228323616
Pubmed

Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.

VEGFC SLIT1

5.63e-044527222696295
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

CCN2 CRIM1 JAG1

6.03e-0421427322199357
Pubmed

The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.

CCN2 NTNG2

6.40e-044827232386544
Cytoband17q25.3

C1QTNF1 DUS1L

1.62e-0310127217q25.3
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

PI4K2B SP110

9.13e-0451162870
GeneFamilyPHD finger proteins

KMT2D SP110

2.81e-039016288
CoexpressionNABA_MATRISOME

VEGFC KCP CHRD C1QTNF1 CCN2 NTNG2 CRIM1 ADAM8 SSPOP SLIT1

3.14e-0810082710MM17056
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP CCN2 NTNG2 CRIM1 SSPOP SLIT1

3.61e-08191276MM17059
CoexpressionNABA_MATRISOME

VEGFC KCP CHRD C1QTNF1 CCN2 NTNG2 CRIM1 ADAM8 SSPOP SLIT1

3.72e-0810262710M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP CCN2 NTNG2 CRIM1 SSPOP SLIT1

4.21e-08196276M3008
CoexpressionNABA_CORE_MATRISOME

KCP CCN2 NTNG2 CRIM1 SSPOP SLIT1

2.79e-07270276MM17057
CoexpressionNABA_CORE_MATRISOME

KCP CCN2 NTNG2 CRIM1 SSPOP SLIT1

3.11e-07275276M5884
CoexpressionGU_PDEF_TARGETS_DN

VEGFC KRT33A ITGB6

9.39e-0640273M10480
CoexpressionHAY_BONE_MARROW_STROMAL

VEGFC CHRD C1QTNF1 CCN2 CRIM1 ITGB6 JAG1

9.52e-06767277M39209
CoexpressionGSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN

VEGFC PI4K2B CHRD SERINC1

5.03e-05200274M4140
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN

VEGFC CCN2 ADAM8 ITGB6

1.70e-04274274M289
CoexpressionKRAS.600_UP.V1_UP

VEGFC C1QTNF1 ADAM8 SLIT1

1.82e-04279274M2882
CoexpressionMASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN

CCN2 ITGB6

1.92e-0420272M1991
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRD CELSR3 ITGB6 SLIT1

3.01e-061672743dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRD CELSR3 ITGB6 SLIT1

3.01e-0616727495b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRD CELSR3 ITGB6 SLIT1

3.01e-061672749480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1 JAG1

3.87e-06178274ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1 JAG1

3.87e-0617827487b04753650e45f12299c8456fb980d6c0d5961c
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1 JAG1

3.87e-06178274ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCellCOPD-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

VEGFC C1QTNF1 CCN2 CRIM1

3.96e-061792749968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCellCOPD-Endothelial-VE_Venous|COPD / Disease state, Lineage and Cell class

VEGFC C1QTNF1 CCN2 CRIM1

4.41e-0618427444d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1 JAG1

4.61e-06186274ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1 JAG1

4.61e-06186274ed924852cd7132c8f6703522037dc22bd2c83193
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

C1QTNF1 CCN2 CRIM1 JAG1

5.01e-06190274d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellControl-Endothelial-VE_Venous|Control / Disease state, Lineage and Cell class

VEGFC C1QTNF1 CCN2 CRIM1

5.12e-06191274617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

C1QTNF1 CCN2 CRIM1 JAG1

5.12e-06191274fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellIPF-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

VEGFC C1QTNF1 CCN2 CRIM1

5.33e-06193274ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell5'-Adult-Distal_Rectal-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VEGFC CCN2 CRIM1 JAG1

5.90e-061982748d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCelldistal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHRD CCN2 CRIM1 JAG1

5.90e-0619827437ce7b485ffb207e75afd1b576b486c6d59fc136
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

VEGFC C1QTNF1 CCN2 JAG1

5.90e-06198274bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VEGFC CCN2 CRIM1 JAG1

5.90e-06198274d1f54ed3ef5e05ebda7da999e172d168dc6802cd
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

KCP C1QTNF1 CRIM1 JAG1

6.14e-062002748c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KCP C1QTNF1 CCN2 CRIM1

6.14e-06200274cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C1QTNF1 CCN2 CRIM1 JAG1

6.14e-06200274c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VEGFC C1QTNF1 CRIM1

5.69e-05124273690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

C1QTNF1 CCN2 CRIM1

1.28e-0416327351dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

SERINC1 JAG1 SLIT1

1.28e-041632734104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 ADAM8 JAG1

1.33e-04165273eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCellfacs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRD C1QTNF1 SSPOP

1.43e-04169273b798b91567d2f49082e2d8a337169f241c8d2080
ToppCellfacs-Lung-Endomucin-24m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CRIM1 JAG1

1.43e-04169273d2862a7ddee6d7a65d84ef9d0800ba6f4690973f
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CRIM1 JAG1

1.43e-041692738dba7546adc6b1345933eec81fc77fc9611fae60
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CCN2 CRIM1

1.45e-0417027367d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CCN2 JAG1

1.45e-0417027350c6c571591aa4b218caefe5778c570c809f567e
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CCN2 CRIM1

1.45e-041702738e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CCN2 JAG1

1.45e-041702738fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CCN2 JAG1

1.45e-041702733232db50b1a40f861e981a1b9c9073b81af9f832
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC ASPHD1 CELSR3

1.48e-0417127325493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC ASPHD1 CELSR3

1.48e-04171273508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC ASPHD1 CELSR3

1.53e-0417327363f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B CELSR3 ITGB6

1.55e-04174273edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP CCN2 JAG1

1.55e-04174273a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

TMEM63B CELSR3 ITGB6

1.55e-0417427365539f69100db0b7d90b1b39ee15ab8281f86461
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B SSPOP SLIT1

1.61e-041762733766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2B SSPOP SLIT1

1.61e-04176273aa1bada2175d8370fc71939a607407155259d195
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VEGFC NTNG2 SLIT1

1.63e-0417727364fbf799e7b0c4003b2f486cc41b0f7e7c11ea0c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

C1QTNF1 CCN2 LRFN1

1.63e-04177273b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1QTNF1 ASPHD1 CRIM1

1.63e-04177273d731400997afea379f47ae8aa0f82802962b0861
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC C1QTNF1 JAG1

1.63e-04177273d68132e145bd413404fdbe215b5dbe520e756e50
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCN2 CRIM1 JAG1

1.66e-04178273066dbc4cc2083c549d98122ed44707127f34d582
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CRIM1 JAG1

1.66e-041782735cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CRIM1 JAG1

1.66e-04178273f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellCOPD-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

C1QTNF1 CCN2 CRIM1

1.69e-04179273e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CRIM1 JAG1

1.72e-04180273fcd5d5bf00ee728162b0aac4c81eb78e742cf6f2
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CRIM1 JAG1

1.72e-04180273c2a8f61c806f6f6f47743e9f7c9700705db43386
ToppCellfacs-Lung-24m-Endothelial-venous_endothelial-vein_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CRIM1 JAG1

1.72e-04180273178648429686e6d4e6f3aafc350130e819788ecf
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

C1QTNF1 CCN2 CRIM1

1.72e-0418027327e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VEGFC NTNG2 SLIT1

1.74e-041812733e3c903b522dced6bec5dc447cc3f8bf9a9749e3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VEGFC NTNG2 SLIT1

1.74e-0418127313270b6ba6a9c8e5681c6f40000c643ce1d9344a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VEGFC NTNG2 SLIT1

1.74e-04181273b9fe3833a6a56b9fbe5c257393fdbea5bf8ac4a3
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

VEGFC C1QTNF1 JAG1

1.77e-04182273e67f3234165199085c793915ebb1f9bbd845e933
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CHRD C1QTNF1 SLIT1

1.77e-0418227346c213597445b1f4f09dc367f27702d24b201daf
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CHRD C1QTNF1 SLIT1

1.80e-041832734617b18da8d699a44e4c47980197b1e7eb951470
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

CCN2 SP110 ITGB6

1.80e-041832738f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

VEGFC C1QTNF1 CRIM1

1.80e-0418327346be9f96755c7b65aeac061d95d15abeb6466034
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VEGFC CRIM1 JAG1

1.80e-04183273fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

VEGFC CRIM1 JAG1

1.83e-04184273b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VEGFC CCN2 JAG1

1.83e-04184273842473fa415575441b595073a994b6d621169776
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

CCN2 CRIM1 JAG1

1.86e-04185273bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

LRFN1 ASPHD1 DUS1L

1.86e-041852739d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C1QTNF1 CRIM1 JAG1

1.89e-041862734780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

KCNQ2 ASPHD1 CELSR3

1.89e-041862733f889083fcffe516388e9b03a5e23af2010ced33
ToppCellE17.5-Epithelial-alveolar_epithelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM63B PI4K2B ITGB6

1.89e-04186273a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

KCNQ2 ASPHD1 CELSR3

1.89e-041862739d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCelldroplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CRIM1 JAG1

1.92e-0418727364dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCP CCN2 CRIM1

1.92e-04187273fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

C1QTNF1 CCN2 CRIM1

1.92e-04187273e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCelldroplet-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFC CRIM1 JAG1

1.92e-04187273b535d5447bf15e95dcf025a0a455628b956fc857
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

KCNQ2 ASPHD1 CELSR3

1.95e-04188273b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

VEGFC CRIM1 JAG1

1.95e-041882732777eb7689b271c199021fe7d9db88ccebff14de
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|normal_Lung / Location, Cell class and cell subclass

CHRD CCN2 CRIM1

1.95e-04188273fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

TMEM63B CDCA7 ITGB6

1.98e-041892732d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

VEGFC CCN2 CRIM1

1.98e-04189273f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCellE18.5-samps-Epithelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMEM63B PI4K2B ITGB6

2.01e-0419027390accc078e9a72329a415d5cefe062c4196bb624
ToppCellE17.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM63B CCN2 ITGB6

2.01e-0419027315f314517ed47b12d287a12a7d18cb383310e25a
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KCNQ2 ASPHD1 CELSR3

2.01e-04190273416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRD C1QTNF1 CRIM1

2.01e-04190273136ca6da77a202874376af193a1dd71d810c76c4
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

C1QTNF1 CCN2 CRIM1

2.01e-041902734e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 JAG1

2.01e-041902733b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NTNG2 KMT2D ADAM8

2.01e-041902733f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VEGFC CRIM1 JAG1

2.04e-04191273b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMEM63B PI4K2B ITGB6

2.04e-041912731cd4d513ac363fdda07030b85a88174d29af3588
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|343B / Donor, Lineage, Cell class and subclass (all cells)

VEGFC CCN2 CRIM1

2.04e-041912731dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

CHRD ASPHD1 CELSR3

2.04e-0419127376311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|343B / Donor, Lineage, Cell class and subclass (all cells)

VEGFC CCN2 CRIM1

2.04e-0419127327a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TMEM63B CCN2 ITGB6

2.08e-04192273be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VEGFC CCN2 CRIM1

2.08e-04192273eafead22bba48ac5ee568faa8946c444445c1034
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

C1QTNF1 CCN2 JAG1

2.08e-04192273a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCellMatrixFB-Fibroblast-D_(Pericyte)|MatrixFB / shred on cell class and cell subclass (v4)

CCN2 CRIM1 JAG1

2.08e-04192273630444302511f511ec6976bc045a3b4b9d8d4547
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1

2.08e-04192273452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1

2.08e-041922737ddaca206599603d4d0b2afb73ed2850225d277d
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRD C1QTNF1 CRIM1

2.08e-041922737aadc7c5bd03274f9861dde2febda5c37f8afc9c
ToppCellControl-Myeloid-MoAM4|Control / Disease group,lineage and cell class （2021.01.30）

KCP ASPHD1 ADAM8

2.08e-041922731da7c303a2e36af4a9d8ec30a11380d9b1897922
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEGFC CCN2 CRIM1

2.08e-04192273bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ComputationalGenes in the cancer module 178.

VEGFC JAG1

3.16e-0417172MODULE_178
ComputationalAngiogenesis.

VEGFC JAG1

4.86e-0421172MODULE_362
Diseasepulmonary fibrosis (biomarker_via_orthology)

CCN2 JAG1

8.91e-0450262DOID:3770 (biomarker_via_orthology)
Diseaseovarian cancer (is_marker_for)

VEGFC CCN2

1.64e-0368262DOID:2394 (is_marker_for)
Diseaseanorexia nervosa

NTNG2 CELSR3

1.74e-0370262MONDO_0005351
Diseaseliver cirrhosis (is_marker_for)

VEGFC ITGB6

2.37e-0382262DOID:5082 (is_marker_for)
Diseaseulcerative colitis

KCP CELSR3 SLIT1

3.11e-03335263EFO_0000729
DiseaseTinnitus

CHRD CDCA7

5.84e-03130262HP_0000360

Protein segments in the cluster

PeptideGeneStartEntry
PKGNRCVFSLCRGCC

DUS1L

401

Q6P1R4
QCDCGPPEDCRNRCC

ADAM8

421

P78325
CRRKCCPGNCPPCDQ

NFXL1

481

Q6ZNB6
CPGNCPPCDQNCGRT

NFXL1

486

Q6ZNB6
PPCDQNCGRTLGCRN

NFXL1

491

Q6ZNB6
AGASRGQPCPGRCIC

LRFN1

26

Q9P244
QAGRCQPSNCRRCPG

ASPHD1

256

Q5U4P2
RLLRPLHCGCSCCPC

PLSCR3

151

Q9NRY6
RCPTCGDPCNSKRSC

ITGB6

616

P18564
CRGPLCGCCPGRSSQ

KCNQ2

421

O43526
ISNPCGLRARCGPCN

KRT33A

386

O76009
CPCCFGRGCLIPNQG

PI4K2B

171

Q8TCG2
QGLPASRCLRCCDPG

C1QTNF1

66

Q9BXJ1
SRPAVGQNCSGPCRC

CCN2

21

P29279
VCKCQGCTCRGEPRP

TMEM63B

381

Q5T3F8
GECCPLPSRCVCNPA

CRIM1

201

Q9NZV1
CPCRPGALGRQCNSC

CELSR3

2096

Q9NYQ7
GPECNRAICRQGCSP

JAG1

226

P78504
GGTCLQNQRCACPRG

NTNG2

466

Q96CW9
ACPCGPCQRARCQER

TGIF2LY

156

Q8IUE0
VQCLQGPCRPGCRCP

SSPOP

4696

A2VEC9
CVRPCVPGCQCPAGL

KCP

1516

Q6ZWJ8
CQGGQLLCCGTCPRV

SP110

541

Q9HB58
APCLLCRCCPSGNNS

SERINC1

21

Q9NRX5
PPCRGICNCSFCRQR

CDCA7

321

Q9BWT1
CGQPRQLPGHCCQTC

CHRD

111

Q9H2X0
CQCVCRAGLRPASCG

VEGFC

291

P49767
PRCCRRATPVCCAGQ

UNQ6494/PRO21346

71

Q6UXR6
GGCLPRPQCPQECAC

SLIT1

726

O75093
GPVRRCALCNCGEPS

KMT2D

61

O14686