Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA6 CHRNA3	3.33e-04	17	32	2	GO:0022848
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNA6 CHRNA3	6.16e-04	23	32	2	GO:0015464
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	CHRNA6 CHRNA3	2.16e-03	43	32	2	GO:0005231
GeneOntologyMolecularFunction	protein serine/threonine/tyrosine kinase activity	DYRK4 MAPK10	2.57e-03	47	32	2	GO:0004712
GeneOntologyMolecularFunction	integrin binding	PDIA4 FAP FN1	2.72e-03	175	32	3	GO:0005178
GeneOntologyMolecularFunction	protease binding	FAP FN1 MIF	2.99e-03	181	32	3	GO:0002020
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA2 FN1 LAMA1	3.33e-03	188	32	3	GO:0005201
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	CHRNA6 ANO3 CHRNA3	3.59e-03	193	32	3	GO:0015276
GeneOntologyMolecularFunction	peptidase activity	RHBDD2 USP10 ADAM29 FAP CPA3	3.59e-03	654	32	5	GO:0008233
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity	PDIA4 MIF	3.76e-03	57	32	2	GO:0016860
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNA6 CHRNA3	3.76e-03	57	32	2	GO:1904315
GeneOntologyMolecularFunction	ligand-gated channel activity	CHRNA6 ANO3 CHRNA3	3.80e-03	197	32	3	GO:0022834
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	CHRNA6 CHRNA3	4.16e-03	60	32	2	GO:0099529
GeneOntologyMolecularFunction	endopeptidase activity	RHBDD2 USP10 ADAM29 FAP	4.73e-03	430	32	4	GO:0004175
GeneOntologyMolecularFunction	transmitter-gated channel activity	CHRNA6 CHRNA3	4.86e-03	65	32	2	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	CHRNA6 CHRNA3	4.86e-03	65	32	2	GO:0022824
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	CHRNA6 CHRNA3	6.42e-03	75	32	2	GO:0098960
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	CHRNA6 CHRNA3	6.75e-03	77	32	2	GO:0005230
GeneOntologyBiologicalProcess	synaptic transmission, cholinergic	LAMA2 CHRNA6 CHRNA3	4.30e-05	44	32	3	GO:0007271
GeneOntologyCellularComponent	basement membrane	LAMA2 FREM2 FN1 LAMA1	3.50e-05	122	32	4	GO:0005604
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMA2 LAMA1	3.04e-04	17	32	2	GO:0098637
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRNA6 CHRNA3	3.42e-04	18	32	2	GO:0005892
GeneOntologyCellularComponent	extracellular matrix	LAMA2 FREM2 CPA3 FCGBP FN1 LAMA1	4.21e-04	656	32	6	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	LAMA2 FREM2 CPA3 FCGBP FN1 LAMA1	4.28e-04	658	32	6	GO:0030312
GeneOntologyCellularComponent	dopaminergic synapse	CHRNA6 CHRNA3	5.14e-04	22	32	2	GO:0098691
GeneOntologyCellularComponent	collagen-containing extracellular matrix	LAMA2 FREM2 CPA3 FN1 LAMA1	1.18e-03	530	32	5	GO:0062023
Domain	Laminin_aI	LAMA2 LAMA1	2.83e-05	5	32	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA1	2.83e-05	5	32	2	PF06008
Domain	Laminin_II	LAMA2 LAMA1	2.83e-05	5	32	2	PF06009
Domain	Laminin_domII	LAMA2 LAMA1	2.83e-05	5	32	2	IPR010307
Domain	LAMININ_IVA	LAMA2 LAMA1	7.91e-05	8	32	2	PS51115
Domain	Laminin_B	LAMA2 LAMA1	7.91e-05	8	32	2	PF00052
Domain	LamB	LAMA2 LAMA1	7.91e-05	8	32	2	SM00281
Domain	Laminin_IV	LAMA2 LAMA1	7.91e-05	8	32	2	IPR000034
Domain	Laminin_G_1	LAMA2 LAMA1	1.55e-04	11	32	2	PF00054
Domain	LAMININ_NTER	LAMA2 LAMA1	3.36e-04	16	32	2	PS51117
Domain	Laminin_N	LAMA2 LAMA1	3.36e-04	16	32	2	PF00055
Domain	Nicotinic_acetylcholine_rcpt	CHRNA6 CHRNA3	3.36e-04	16	32	2	IPR002394
Domain	Laminin_N	LAMA2 LAMA1	3.36e-04	16	32	2	IPR008211
Domain	LamNT	LAMA2 LAMA1	3.36e-04	16	32	2	SM00136
Domain	Acetylcholine_rcpt_TM	CHRNA6 CHRNA3	7.04e-04	23	32	2	IPR027361
Domain	-	CHRNA6 CHRNA3	7.04e-04	23	32	2	1.20.120.370
Domain	EGF-like_dom	LAMA2 ADAM29 FCGBP LAMA1	8.27e-04	249	32	4	IPR000742
Domain	EGF_1	LAMA2 ADAM29 FN1 LAMA1	9.03e-04	255	32	4	PS00022
Domain	EGF-like_CS	LAMA2 ADAM29 FN1 LAMA1	9.85e-04	261	32	4	IPR013032
Domain	EGF_LAM_2	LAMA2 LAMA1	1.20e-03	30	32	2	PS50027
Domain	EGF_LAM_1	LAMA2 LAMA1	1.20e-03	30	32	2	PS01248
Domain	Laminin_EGF	LAMA2 LAMA1	1.63e-03	35	32	2	PF00053
Domain	EGF_Lam	LAMA2 LAMA1	1.63e-03	35	32	2	SM00180
Domain	LAM_G_DOMAIN	LAMA2 LAMA1	1.92e-03	38	32	2	PS50025
Domain	Laminin_EGF	LAMA2 LAMA1	1.92e-03	38	32	2	IPR002049
Domain	Laminin_G_2	LAMA2 LAMA1	2.13e-03	40	32	2	PF02210
Domain	LamG	LAMA2 LAMA1	2.57e-03	44	32	2	SM00282
Domain	Neurotransmitter_ion_chnl_CS	CHRNA6 CHRNA3	2.69e-03	45	32	2	IPR018000
Domain	Neur_chan_memb	CHRNA6 CHRNA3	2.81e-03	46	32	2	PF02932
Domain	Neur_chan_LBD	CHRNA6 CHRNA3	2.93e-03	47	32	2	PF02931
Domain	Neur_channel	CHRNA6 CHRNA3	2.93e-03	47	32	2	IPR006201
Domain	Neur_chan_lig-bd	CHRNA6 CHRNA3	2.93e-03	47	32	2	IPR006202
Domain	NEUROTR_ION_CHANNEL	CHRNA6 CHRNA3	2.93e-03	47	32	2	PS00236
Domain	Neurotrans-gated_channel_TM	CHRNA6 CHRNA3	2.93e-03	47	32	2	IPR006029
Domain	-	CHRNA6 CHRNA3	2.93e-03	47	32	2	2.70.170.10
Domain	Laminin_G	LAMA2 LAMA1	4.43e-03	58	32	2	IPR001791
Domain	EGF	LAMA2 FCGBP LAMA1	7.45e-03	235	32	3	SM00181
Domain	EGF_2	LAMA2 ADAM29 LAMA1	1.03e-02	265	32	3	PS01186
Domain	Galactose-bd-like	LAMA2 LAMA1	1.13e-02	94	32	2	IPR008979
Domain	-	LAMA2 LAMA1	1.15e-02	95	32	2	2.60.120.200
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA2 FN1 LAMA1	2.75e-05	30	28	3	M27772
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 FN1 LAMA1	7.11e-05	41	28	3	M27778
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA3	1.36e-04	9	28	2	M27597
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA3	1.36e-04	9	28	2	MM15313
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMA1	2.07e-04	11	28	2	M158
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA3	2.07e-04	11	28	2	M883
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMA2 FN1 LAMA1	2.12e-04	59	28	3	M27218
Pathway	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA3	2.48e-04	12	28	2	M48008
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA3	2.48e-04	12	28	2	MM15312
Pathway	PID_INTEGRIN1_PATHWAY	LAMA2 FN1 LAMA1	2.95e-04	66	28	3	M18
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA6 CHRNA3	3.41e-04	14	28	2	M757
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA6 CHRNA3	3.93e-04	15	28	2	MM14704
Pathway	REACTOME_ECM_PROTEOGLYCANS	LAMA2 FN1 LAMA1	4.48e-04	76	28	3	M27219
Pathway	REACTOME_SIGNALING_BY_MET	LAMA2 FN1 LAMA1	5.02e-04	79	28	3	M27643
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA2 FN1 LAMA1	6.00e-04	84	28	3	M3228
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA2 FN1 LAMA1	6.00e-04	84	28	3	M7098
Pathway	WP_FOCAL_ADHESION	LAMA2 FN1 MAPK10 LAMA1	6.05e-04	199	28	4	M39402
Pathway	KEGG_FOCAL_ADHESION	LAMA2 FN1 MAPK10 LAMA1	6.05e-04	199	28	4	M7253
Pathway	WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS	CHRNA6 CHRNA3	7.81e-04	21	28	2	M39343
Pathway	WP_SMALL_CELL_LUNG_CANCER	LAMA2 FN1 LAMA1	8.86e-04	96	28	3	M39834
Pathway	WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING	FN1 MAPK10	1.39e-03	28	28	2	M39572
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA2 LAMA1	1.60e-03	30	28	2	M27216
Pathway	BIOCARTA_AGR_PATHWAY	LAMA2 LAMA1	1.71e-03	31	28	2	MM1343
Pathway	PID_SYNDECAN_4_PATHWAY	FN1 LAMA1	1.82e-03	32	28	2	M165
Pathway	PID_SYNDECAN_2_PATHWAY	FN1 LAMA1	1.93e-03	33	28	2	M240
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 LAMA1	1.93e-03	33	28	2	M39503
Pathway	REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION	SNRPA1 MIF	2.56e-03	38	28	2	M27820
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	LAMA2 FREM2 FN1 LAMA1	1.38e-08	29	32	4	22613833
Pubmed	Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.	LAMA2 FN1 LAMA1	5.92e-08	9	32	3	9882526
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	LAMA2 FREM2 FAP FCGBP FN1 CD109	1.18e-07	257	32	6	16335952
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	LAMA2 FN1 LAMA1	2.01e-07	13	32	3	9833687
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	LAMA2 FN1 LAMA1	3.93e-07	16	32	3	17948866
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 FN1 LAMA1	5.72e-07	18	32	3	11311202
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	LAMA2 FREM2 LAMA1	5.72e-07	18	32	3	14730302
Pubmed	Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan.	LAMA2 LAMA1	8.20e-07	2	32	2	20544910
Pubmed	Acidic glycosaminoglycans and laminin-1 in renal corpuscles of mutant blebs (my) and control mice.	FREM2 LAMA1	8.20e-07	2	32	2	9302549
Pubmed	Conserved neuron promoting activity in Drosophila and vertebrate laminin alpha1.	LAMA2 LAMA1	8.20e-07	2	32	2	8663504
Pubmed	Laminin α1 reduces muscular dystrophy in dy2J mice.	LAMA2 LAMA1	8.20e-07	2	32	2	29544677
Pubmed	Laminin 2 attachment selects myofibroblasts from fetal mouse lung.	LAMA2 LAMA1	8.20e-07	2	32	2	9728058
Pubmed	Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency.	LAMA2 LAMA1	8.20e-07	2	32	2	20657839
Pubmed	Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression.	FN1 LAMA1	8.20e-07	2	32	2	25885552
Pubmed	Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.	FN1 LAMA1	8.20e-07	2	32	2	16677310
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	LAMA2 FN1 LAMA1	1.60e-06	25	32	3	19373938
Pubmed	Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier.	NFASC FN1	2.46e-06	3	32	2	22009740
Pubmed	Expression of laminin chains during myogenic differentiation.	LAMA2 LAMA1	2.46e-06	3	32	2	7510707
Pubmed	Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.	LAMA2 LAMA1	2.46e-06	3	32	2	7925941
Pubmed	Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.	LAMA2 LAMA1	2.46e-06	3	32	2	16504180
Pubmed	PDGFRβ-positive cell-mediated post-stroke remodeling of fibronectin and laminin α2 for tissue repair and functional recovery.	LAMA2 FN1	2.46e-06	3	32	2	36514952
Pubmed	The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells.	FN1 LAMA1	2.46e-06	3	32	2	22919069
Pubmed	Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.	LAMA2 LAMA1	2.46e-06	3	32	2	7803849
Pubmed	Bidirectional sex-dependent regulation of α6 and β3 nicotinic acetylcholine receptors by protein kinase Cε.	CHRNA6 CHRNA3	2.46e-06	3	32	2	32776643
Pubmed	Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.	LAMA2 LAMA1	2.46e-06	3	32	2	16709410
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	LAMA2 FN1 MIF LAMA1 CD109	3.05e-06	248	32	5	24006456
Pubmed	The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator.	FN1 LAMA1	4.92e-06	4	32	2	8360181
Pubmed	Expression of CD 73 (ecto-5'-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry.	FN1 LAMA1	4.92e-06	4	32	2	10470109
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMA2 LAMA1	4.92e-06	4	32	2	2099832
Pubmed	Molecular recognition by LARGE is essential for expression of functional dystroglycan.	LAMA2 LAMA1	4.92e-06	4	32	2	15210115
Pubmed	Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.	LAMA2 LAMA1	4.92e-06	4	32	2	9201115
Pubmed	Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.	LAMA2 LAMA1	4.92e-06	4	32	2	32072250
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA2 LAMA1	8.19e-06	5	32	2	11969289
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA2 LAMA1	8.19e-06	5	32	2	11829758
Pubmed	Immunohistochemical localization of Pax2 and associated proteins in the developing kidney of mice with renal hypoplasia.	FN1 LAMA1	8.19e-06	5	32	2	11511678
Pubmed	The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes.	FN1 LAMA1	8.19e-06	5	32	2	28092265
Pubmed	Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.	CHRNA6 CHRNA3	8.19e-06	5	32	2	20418888
Pubmed	Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections.	LAMA2 LAMA1	8.19e-06	5	32	2	8613743
Pubmed	Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin.	FN1 LAMA1	8.19e-06	5	32	2	9169408
Pubmed	Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.	LAMA2 LAMA1	8.19e-06	5	32	2	9415429
Pubmed	Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.	LAMA2 LAMA1	8.19e-06	5	32	2	8719886
Pubmed	Differential expression of laminin alpha chains during murine tooth development.	LAMA2 LAMA1	8.19e-06	5	32	2	9389447
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LAMA2 CPA3 FN1 MIF	9.78e-06	146	32	4	27068509
Pubmed	Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.	LAMA2 LAMA1	1.23e-05	6	32	2	1678389
Pubmed	Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.	LAMA2 LAMA1	1.23e-05	6	32	2	23948589
Pubmed	Essential role of alpha 6 integrins in cortical and retinal lamination.	LAMA2 LAMA1	1.23e-05	6	32	2	9742403
Pubmed	Entactin: structure and function.	LAMA2 LAMA1	1.23e-05	6	32	2	2119632
Pubmed	Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.	FN1 LAMA1	1.23e-05	6	32	2	28348210
Pubmed	HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.	LAMA2 LAMA1	1.23e-05	6	32	2	9597096
Pubmed	Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.	LAMA2 LAMA1	1.23e-05	6	32	2	22270369
Pubmed	Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.	LAMA2 LAMA1	1.23e-05	6	32	2	26555376
Pubmed	Effect of basement membrane entactin on epidermal cell attachment and growth.	LAMA2 LAMA1	1.23e-05	6	32	2	3794389
Pubmed	Laminin regulates PDGFRβ(+) cell stemness and muscle development.	LAMA2 LAMA1	1.23e-05	6	32	2	27138650
Pubmed	Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer.	LAMA2 FN1	1.23e-05	6	32	2	19893454
Pubmed	Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.	FN1 LAMA1	1.23e-05	6	32	2	20874775
Pubmed	Laminin-nidogen complex. Extraction with chelating agents and structural characterization.	LAMA2 LAMA1	1.23e-05	6	32	2	3109910
Pubmed	Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.	LAMA2 FN1 LAMA1	1.35e-05	50	32	3	24191021
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	LAMA2 FREM2 FN1 LAMA1	1.66e-05	167	32	4	22159717
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA2 LAMA1	1.72e-05	7	32	2	14557481
Pubmed	A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex.	FN1 LAMA1	1.72e-05	7	32	2	26988758
Pubmed	Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system.	LAMA2 LAMA1	1.72e-05	7	32	2	8950511
Pubmed	Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice.	LAMA2 LAMA1	1.72e-05	7	32	2	9390664
Pubmed	Functional interaction between Lypd6 and nicotinic acetylcholine receptors.	CHRNA6 CHRNA3	2.29e-05	8	32	2	27344019
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA2 LAMA1	2.29e-05	8	32	2	9852162
Pubmed	Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells.	FN1 LAMA1	2.29e-05	8	32	2	19633172
Pubmed	Laminin-1 promotes differentiation of fetal mouse pancreatic beta-cells.	LAMA2 LAMA1	2.29e-05	8	32	2	10102687
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA2 LAMA1	2.29e-05	8	32	2	8872465
Pubmed	Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.	FN1 LAMA1	2.29e-05	8	32	2	19651211
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	LAMA2 FN1 LAMA1	2.84e-05	64	32	3	22261194
Pubmed	Detection of gelatinolytic activity in developing basement membranes of the mouse embryo head by combining sensitive in situ zymography with immunolabeling.	FN1 LAMA1	2.94e-05	9	32	2	22688677
Pubmed	Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.	FN1 LAMA1	2.94e-05	9	32	2	9827803
Pubmed	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.	CHRNA6 CHRNA3	2.94e-05	9	32	2	8906617
Pubmed	Sources of energy for gating by neurotransmitters in acetylcholine receptor channels.	CHRNA6 CHRNA3	2.94e-05	9	32	2	22647603
Pubmed	Regulation of neural stem cell proliferation and survival by protein arginine methyltransferase 1.	LAMA2 LAMA1	2.94e-05	9	32	2	36440275
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMA1	3.67e-05	10	32	2	9034910
Pubmed	Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.	LAMA2 LAMA1	3.67e-05	10	32	2	18590826
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA2 LAMA1	3.67e-05	10	32	2	11784026
Pubmed	Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.	CHRNA6 CHRNA3	3.67e-05	10	32	2	20736995
Pubmed	SOX17 links gut endoderm morphogenesis and germ layer segregation.	FN1 LAMA1	3.67e-05	10	32	2	25419850
Pubmed	Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.	LAMA2 LAMA1	3.67e-05	10	32	2	20976766
Pubmed	Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.	FN1 LAMA1	3.67e-05	10	32	2	9415455
Pubmed	Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus.	CHRNA6 CHRNA3	4.49e-05	11	32	2	12225896
Pubmed	Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission.	CHRNA6 CHRNA3	4.49e-05	11	32	2	29791835
Pubmed	Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.	LAMA2 LAMA1	4.49e-05	11	32	2	12051813
Pubmed	Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.	LAMA2 FN1	4.49e-05	11	32	2	15739233
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMA1	4.49e-05	11	32	2	21524702
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA2 LAMA1	4.49e-05	11	32	2	23472759
Pubmed	Regulation of radial glial survival by signals from the meninges.	LAMA2 LAMA1	4.49e-05	11	32	2	19535581
Pubmed	Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells.	LAMA2 DYRK4 SNRPA1	4.75e-05	76	32	3	36560452
Pubmed	Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.	LAMA2 LAMA1	5.38e-05	12	32	2	11381080
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA2 LAMA1	5.38e-05	12	32	2	16750824
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	FN1 LAMA1	5.38e-05	12	32	2	12180907
Pubmed	Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.	LAMA2 LAMA1	5.38e-05	12	32	2	12843252
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMA1	5.38e-05	12	32	2	9396756
Pubmed	Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.	CHRNA6 CHRNA3	5.38e-05	12	32	2	20584212
Pubmed	The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.	LAMA2 LAMA1	6.36e-05	13	32	2	36350252
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	LAMA2 LAMA1	6.36e-05	13	32	2	21900571
Pubmed	Loss of Gli3 and Shh function disrupts olfactory axon trajectories.	FN1 LAMA1	7.41e-05	14	32	2	15065125
Pubmed	Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.	CHRNA6 CHRNA3	7.41e-05	14	32	2	19059502
Pubmed	The first draft of the endostatin interaction network.	FN1 LAMA1	7.41e-05	14	32	2	19542224
Cytoband	Ensembl 112 genes in cytogenetic band chr2q35	FN1 TTLL4	3.68e-03	129	32	2	chr2q35
Cytoband	14q11.2	OR4K5 OR10G2	7.02e-03	180	32	2	14q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr18p11	MC5R LAMA1	9.44e-03	210	32	2	chr18p11
GeneFamily	Laminin subunits	LAMA2 LAMA1	1.20e-04	12	25	2	626
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA6 CHRNA3	2.18e-04	16	25	2	173
GeneFamily	Fibronectin type III domain containing	NFASC FN1	2.04e-02	160	25	2	555
Coexpression	KAYO_CALORIE_RESTRICTION_MUSCLE_UP	LAMA2 FAP CPA3 FN1	3.96e-06	94	30	4	M7013
Coexpression	BROWNE_HCMV_INFECTION_48HR_DN	LAMA2 NFASC FAP DYRK4 FN1 VPS39	1.53e-05	482	30	6	M12144
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	FREM2 TTC3 MIF CD109	7.57e-05	199	30	4	M7319
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	LAMA2 FAP FN1 LAMA1	7.72e-05	200	30	4	M5930
Coexpression	LINDVALL_IMMORTALIZED_BY_TERT_DN	NFASC FAP FN1	7.97e-05	73	30	3	M1561
Coexpression	FALVELLA_SMOKERS_WITH_LUNG_CANCER	NFASC USP10 TTC3	1.09e-04	81	30	3	M18536
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.34e-07	190	32	5	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.40e-07	191	32	5	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.40e-07	191	32	5	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.40e-07	191	32	5	bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.59e-07	194	32	5	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.66e-07	195	32	5	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.66e-07	195	32	5	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.73e-07	196	32	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.73e-07	196	32	5	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1 ANO3	2.73e-07	196	32	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MC5R LAMA2 FAP FN1	1.98e-06	126	32	4	c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP ANO3	5.52e-06	163	32	4	8e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP ANO3	5.52e-06	163	32	4	bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell	droplet-Spleen-nan-21m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA3 FCGBP FN1 LAMA1	6.51e-06	170	32	4	03cb4e508356f85372a588c8d1c6babf2a012683
ToppCell	droplet-Spleen-nan-21m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA3 FCGBP FN1 LAMA1	6.67e-06	171	32	4	9498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FAP FN1 ANO3	6.67e-06	171	32	4	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	droplet-Spleen-nan-21m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA3 FCGBP FN1 LAMA1	6.67e-06	171	32	4	db544252f98e073e5bb4bec4a110cd58e6434435
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FAP FN1 ANO3	6.67e-06	171	32	4	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FAP FN1 ANO3	7.47e-06	176	32	4	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FAP FN1 ANO3	7.47e-06	176	32	4	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1	8.34e-06	181	32	4	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1	8.34e-06	181	32	4	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	8.71e-06	183	32	4	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC FAP FN1 ANO3	9.49e-06	187	32	4	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NFASC FAP FN1 ANO3	9.49e-06	187	32	4	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	LAMA2 NFASC FN1 ANO3	9.49e-06	187	32	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PDIA4 FN1 MIF CD109	1.03e-05	191	32	4	cf217d00ba2b0402a8e72fcd64bdb36d5539dde0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.03e-05	191	32	4	7b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.03e-05	191	32	4	cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1	1.07e-05	193	32	4	dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1	1.07e-05	193	32	4	e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	LAMA2 NFASC FAP FN1	1.07e-05	193	32	4	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1	1.10e-05	194	32	4	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	LAMA2 NFASC FAP FN1	1.10e-05	194	32	4	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	LAMA2 NFASC FAP FN1	1.12e-05	195	32	4	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	LAMA2 NFASC FN1 ANO3	1.12e-05	195	32	4	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.14e-05	196	32	4	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.14e-05	196	32	4	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	LAMA2 FN1 MAPK10 ANO3	1.14e-05	196	32	4	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 FAP FN1 MAPK10	1.16e-05	197	32	4	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.16e-05	197	32	4	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP FN1	1.16e-05	197	32	4	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.16e-05	197	32	4	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.16e-05	197	32	4	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FCGBP FN1 MIF CD109	1.16e-05	197	32	4	367aaf277c56962c96ddb4de06949fb33fc6170b
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	LAMA2 FAP FN1 MAPK10	1.16e-05	197	32	4	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FCGBP FN1 MIF CD109	1.19e-05	198	32	4	06e13ba14bda79e01a757ceb9e88de133053df61
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	LAMA2 NFASC FAP FN1	1.19e-05	198	32	4	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FN1 ANO3	1.19e-05	198	32	4	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	LAMA2 NFASC MAPK10 ANO3	1.19e-05	198	32	4	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	background-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	LAMA2 NFASC MAPK10 ANO3	1.19e-05	198	32	4	79f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFASC FAP FN1 CD109	1.24e-05	200	32	4	be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 FAP FN1 ANO3	1.24e-05	200	32	4	b441b3771fb7d9ee7b7a104afc35e466aace2da2
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 NFASC FN1 MAPK10	1.24e-05	200	32	4	a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFASC FAP FN1 CD109	1.24e-05	200	32	4	c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFASC FAP FN1 CD109	1.24e-05	200	32	4	d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCell	droplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NFASC FAP FN1 CD109	1.24e-05	200	32	4	8e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCell	ASK454-Immune\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	CPA3 SNRPA1 MIF	1.61e-04	148	32	3	1076c69bf2a5e4557aa35643fd9bd86e8610815b
ToppCell	metastatic_Lymph_Node-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	LAMA2 ADAM29 LAMA1	1.61e-04	148	32	3	db046a02a00829910bf9d7dbda068e730aa78f00
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP	1.88e-04	156	32	3	363f1b661048d25895e2b8681c82894c957b29c0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC FAP	1.88e-04	156	32	3	d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	LAMA2 CHRNA6 CD109	1.92e-04	157	32	3	c44bd530e396b08f16f284e185dcb830843959ea
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MC5R CPA3 DYRK4	1.99e-04	159	32	3	e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MC5R CPA3 DYRK4	1.99e-04	159	32	3	9db971130509c62d439e0cab16588a4d994d7aa0
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	LAMA2 ANO3 LAMA1	2.07e-04	161	32	3	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FN1 ANO3	2.07e-04	161	32	3	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.10e-04	162	32	3	bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 ANO3 CD109	2.10e-04	162	32	3	56f1789e69a6cb29956e46aba92b290847327c1f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FN1 ANO3	2.22e-04	165	32	3	e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FN1 ANO3	2.22e-04	165	32	3	b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FN1 ANO3	2.22e-04	165	32	3	d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 BPIFB2 FCGBP	2.34e-04	168	32	3	b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 BPIFB2 FCGBP	2.34e-04	168	32	3	0757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FREM2 BPIFB2 FCGBP	2.34e-04	168	32	3	a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 FN1 MAPK10	2.38e-04	169	32	3	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related-FDC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MC5R NFASC FN1	2.38e-04	169	32	3	49a54fb2ea9db5c45e107f304838c536908308bb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.38e-04	169	32	3	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.43e-04	170	32	3	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.43e-04	170	32	3	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FN1 ANO3	2.51e-04	172	32	3	553701349444eb366df3c11f54bb093434f153c6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 FN1 ANO3	2.51e-04	172	32	3	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAP SLC22A5 CD109	2.60e-04	174	32	3	1779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.64e-04	175	32	3	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDIA4 LAMA2 FN1	2.69e-04	176	32	3	fcf324e6402819683f95e0dd94bf1f777c7f4c76
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	PDIA4 FREM2 ANO3	2.78e-04	178	32	3	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDIA4 LAMA2 FN1	2.82e-04	179	32	3	68ccfe66474d049a926afc21bffa231446becc69
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	LAMA2 FN1 ANO3	2.91e-04	181	32	3	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LAMA2 FAP FN1	2.91e-04	181	32	3	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	NFASC FN1 MAPK10	2.96e-04	182	32	3	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.96e-04	182	32	3	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 NFASC FN1	2.96e-04	182	32	3	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LAMA2 FAP SLC22A5	2.96e-04	182	32	3	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 NFASC ANO3	2.96e-04	182	32	3	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 FAP FN1	3.01e-04	183	32	3	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 FAP FN1	3.01e-04	183	32	3	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 FAP FN1	3.01e-04	183	32	3	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 ANO3 LAMA1	3.06e-04	184	32	3	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMA2 FAP FN1	3.06e-04	184	32	3	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 ANO3 LAMA1	3.06e-04	184	32	3	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 ANO3 LAMA1	3.06e-04	184	32	3	2b19a8c5f823e00812908b23e66bb4e563278aff
Drug	BAPTA	PDIA4 CHRNA6 FAP FN1 MAPK10 CHRNA3	5.26e-06	324	32	6	CID000104751
Drug	alpha-conotoxin MII	CHRNA6 CHRNA3	1.15e-05	4	32	2	ctd:C098872
Drug	kalinin	LAMA2 FN1 LAMA1	6.30e-05	55	32	3	CID000032518
Drug	Dns-C6-Cho	CHRNA6 CHRNA3	1.04e-04	11	32	2	CID000124728
Drug	AC1L9NC9	CHRNA6 CHRNA3	1.04e-04	11	32	2	CID000449642
Drug	AC1L1G72	LAMA2 LAMA1	1.04e-04	11	32	2	CID000003553
Drug	dihydronereistoxin	CHRNA6 CHRNA3	1.04e-04	11	32	2	CID000121232
Drug	bipinnatin-B	CHRNA6 CHRNA3	1.04e-04	11	32	2	CID000127363
Drug	LJP 1082	CHRNA6 CHRNA3	1.04e-04	11	32	2	CID003037609
Drug	Prenylamine lactate [69-43-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	PDIA4 LAMA2 CHRNA6 FN1	1.14e-04	180	32	4	5070_UP
Drug	AC1L9P8C	CHRNA6 CHRNA3	1.25e-04	12	32	2	CID000450864
Drug	SureCN373116	CHRNA6 CHRNA3	1.25e-04	12	32	2	CID010085732
Drug	nereistoxin	CHRNA6 CHRNA3	1.48e-04	13	32	2	CID000015401
Drug	1-acetyl-4-methylpiperazine methiodide	CHRNA6 CHRNA3	1.48e-04	13	32	2	CID004392675
Drug	C-toxiferine-I	CHRNA6 CHRNA3	1.48e-04	13	32	2	CID005089093
Drug	bipinnatin-C	CHRNA6 CHRNA3	1.48e-04	13	32	2	CID000129977
Drug	bipinnatin-A	CHRNA6 CHRNA3	1.48e-04	13	32	2	CID000196603
Drug	monastrol; Up 200; 100uM; MCF7; HG-U133A	DYRK4 VPS39 CHRNA3 TTLL4	1.55e-04	195	32	4	311_UP
Drug	Sulindac [38194-50-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	LAMA2 CHRNA6 FN1 MAPK10	1.62e-04	197	32	4	5528_UP
Drug	genistein; Down 200; 10uM; MCF7; HG-U133A	DYRK4 MAPK10 CHRNA3 TTLL4	1.65e-04	198	32	4	638_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HG-U133A	FN1 VPS39 HS2ST1 TTLL4	1.65e-04	198	32	4	421_DN
Drug	Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A	MC5R ADAM29 FN1 MAPK10	1.65e-04	198	32	4	5614_UP
Drug	wortmannin; Up 200; 0.01uM; ssMCF7; HG-U133A	MC5R LAMA2 DYRK4 FN1	1.71e-04	200	32	4	404_UP
Drug	Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; HL60; HG-U133A	PDIA4 CHRNA6 MAPK10 VPS39	1.71e-04	200	32	4	1618_DN
Drug	Varenicline	CHRNA6 CHRNA3	1.72e-04	14	32	2	ctd:D000068580
Drug	2,3-dichlorooctafluorobutane	CHRNA6 CHRNA3	1.72e-04	14	32	2	CID000078982
Drug	LNF 209	CHRNA6 CHRNA3	1.72e-04	14	32	2	CID000132666
Drug	colchine	LAMA2 CHRNA6 FN1 CHRNA3 LAMA1	1.82e-04	383	32	5	CID000002833
Drug	YIGSR	LAMA2 FN1 LAMA1	1.85e-04	79	32	3	CID000123977
Drug	aa373	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID000191672
Drug	(-)-pictamine	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID006918623
Drug	(-)-lepadin B	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID006918624
Drug	SAD-128	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID000162008
Drug	anatoxin-a hydrochloride	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID000135265
Drug	UB-165	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID004694339
Drug	N-methylcytisine	CHRNA6 CHRNA3	1.99e-04	15	32	2	CID000234566
Drug	2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine	LAMA2 FN1 LAMA1	2.15e-04	83	32	3	CID011968896
Drug	AC1L2SVN	CHRNA6 CHRNA3	2.27e-04	16	32	2	CID000127922
Drug	benzoquinonium	CHRNA6 CHRNA3	2.27e-04	16	32	2	CID000009393
Drug	3-(trifluoromethyl)-3-(m-iodophenyl)diazirine	CHRNA6 CHRNA3	2.27e-04	16	32	2	CID000123866
Drug	PNU-282,987	CHRNA6 CHRNA3	2.27e-04	16	32	2	CID004655349
Drug	Nsc36388	CHRNA6 CHRNA3	2.57e-04	17	32	2	CID000014954
Drug	LMWH	LAMA2 CHRNA6 FN1 CHRNA3 HS2ST1 LAMA1	2.83e-04	663	32	6	CID000000772
Drug	ABT-594	CHRNA6 CHRNA3	2.89e-04	18	32	2	CID003075702
Drug	AC1O8PVM	CHRNA6 CHRNA3	2.89e-04	18	32	2	CID000004989
Drug	AC1LCVGE	CHRNA6 CHRNA3	2.89e-04	18	32	2	CID000656712
Drug	benzetimide	CHRNA6 CHRNA3	2.89e-04	18	32	2	CID000021846
Drug	isoarecolone	CHRNA6 CHRNA3	3.22e-04	19	32	2	CID000146970
Drug	beta-erythroidine	CHRNA6 CHRNA3	3.22e-04	19	32	2	CID000010074
Drug	AC1L9P88	CHRNA6 CHRNA3	3.22e-04	19	32	2	CID000450860
Drug	perhydrohistrionicotoxin	CHRNA6 CHRNA3	3.22e-04	19	32	2	CID000107881
Drug	PNU-120596	CHRNA6 CHRNA3	3.22e-04	19	32	2	CID000311434
Drug	4-(N-maleimido)benzyltrimethylammonium	CHRNA6 CHRNA3	3.22e-04	19	32	2	CID000162425
Drug	sulfate	LAMA2 CHRNA6 FN1 MAPK10 CHRNA3 HS2ST1 MIF LAMA1	3.25e-04	1292	32	8	CID000001117
Drug	AC1Q5X7V	CHRNA6 CHRNA3	3.58e-04	20	32	2	CID000050190
Drug	3-(2-azetidinylmethoxy)pyridine	CHRNA6 CHRNA3	3.58e-04	20	32	2	CID000001962
Drug	Dichloride, Alcuronium	CHRNA6 CHRNA3	3.58e-04	20	32	2	CID003032788
Drug	ivermectin	CHRNA6 CHRNA3 LAMA1	3.83e-04	101	32	3	CID006435110
Drug	dinotefuran	CHRNA6 CHRNA3	3.95e-04	21	32	2	CID000197701
Drug	meproadifen	CHRNA6 CHRNA3	3.95e-04	21	32	2	CID000189752
Drug	Betamethasone-d5	MC5R LAMA2 CHRNA6 FN1 MAPK10 CHRNA3 MIF LAMA1	4.16e-04	1340	32	8	CID000003003
Drug	Mustard Gas	MC5R LAMA2 FREM2 FN1 MAPK10 SLC22A5 MIF LAMA1	4.18e-04	1341	32	8	ctd:D009151
Drug	suberyldicholine	CHRNA6 CHRNA3	4.34e-04	22	32	2	CID000123989
Drug	clothianidin	CHRNA6 CHRNA3	4.34e-04	22	32	2	CID000213027
Drug	AR-R17779	CHRNA6 CHRNA3	4.34e-04	22	32	2	CID005310971
Drug	histrionicotoxin	CHRNA6 CHRNA3	4.34e-04	22	32	2	CID005282247
Drug	ABT-418	CHRNA6 CHRNA3	4.75e-04	23	32	2	CID000119380
Drug	AC1L3BL8	CHRNA6 CHRNA3	4.75e-04	23	32	2	CID000086457
Drug	alpha-conotoxin SI	CHRNA6 CHRNA3	4.75e-04	23	32	2	CID000163979
Drug	Skpymrfamide	CHRNA6 CHRNA3	4.75e-04	23	32	2	CID000132661
Drug	alpha-conotoxin ImI	CHRNA6 CHRNA3	4.75e-04	23	32	2	CID000133011
Drug	CID6325740	CHRNA6 CHRNA3	4.75e-04	23	32	2	CID006325740
Drug	AC1O0B8G	LAMA2 FAP MAPK10 LAMA1	4.78e-04	262	32	4	CID000091605
Drug	procyclidine	CHRNA6 CHRNA3	5.18e-04	24	32	2	CID000004919
Drug	Sikvav	FN1 LAMA1	5.18e-04	24	32	2	CID005487517
Drug	AC1L2IZE	CHRNA6 CHRNA3	5.18e-04	24	32	2	CID000072928
Drug	intruder	CHRNA6 CHRNA3	5.18e-04	24	32	2	CID000213021
Drug	anabaseine	CHRNA6 CHRNA3	5.18e-04	24	32	2	CID000018985
Drug	anabasine	CHRNA6 CHRNA3	5.63e-04	25	32	2	CID000002181
Drug	pempidine	CHRNA6 CHRNA3	5.63e-04	25	32	2	CID000006603
Drug	varenicline	CHRNA6 CHRNA3	5.63e-04	25	32	2	CID000170361
Drug	PrBCM	CHRNA6 CHRNA3	5.63e-04	25	32	2	CID000037396
Drug	benzquinamide	CHRNA6 CHRNA3	6.09e-04	26	32	2	CID000002342
Drug	beta-eudesmol	CHRNA6 CHRNA3	6.09e-04	26	32	2	CID000091457
Drug	curarine	CHRNA6 CHRNA3	6.09e-04	26	32	2	CID000198004
Drug	AC1O0V2G	CHRNA6 CHRNA3	6.09e-04	26	32	2	CID006102809
Drug	imidazolidine	CHRNA6 CHRNA3	6.09e-04	26	32	2	CID000449488
Drug	methylcarbamylcholine	CHRNA6 CHRNA3	6.57e-04	27	32	2	CID000004136
Drug	nornicotine	CHRNA6 CHRNA3	6.57e-04	27	32	2	CID000000412
Drug	Clorocruoro Hem	CHRNA6 MAPK10 CHRNA3	6.81e-04	123	32	3	CID003518809
Drug	bicinchoninic acid	FN1 MIF	7.07e-04	28	32	2	CID000071068
Drug	echothiophate	CHRNA6 CHRNA3	7.07e-04	28	32	2	CID000010547
Drug	pentolinium	CHRNA6 CHRNA3	7.07e-04	28	32	2	CID000005849
Drug	bifemelane	CHRNA6 CHRNA3	7.59e-04	29	32	2	CID000002377
Drug	bromoacetylcholine bromide	CHRNA6 CHRNA3	7.59e-04	29	32	2	CID000204966
Drug	AC1L1B58	LAMA2 LAMA1	7.59e-04	29	32	2	CID000001288
Drug	vecuronium	CHRNA6 CHRNA3	8.12e-04	30	32	2	CID000039764
Drug	methylenedioxydimethylamphetamine	CHRNA6 CHRNA3	8.12e-04	30	32	2	CID000551630
Drug	55528-53-5	FN1 SLC22A5	8.68e-04	31	32	2	CID000115146
Drug	tetrahydrodeoxycortisol	CHRNA6 CHRNA3	8.68e-04	31	32	2	CID000010593
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CHRNA6 CHRNA3	7.00e-05	12	31	2	C1861063
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA6 CHRNA3	1.27e-04	16	31	2	DOID:3635 (implicated_via_orthology)
Disease	Malignant mesothelioma	FN1 SLC22A5 MIF	2.04e-04	109	31	3	C0345967
Disease	Schizophrenia	MC5R LAMA2 NFASC VPS39 CHRNA3 LAMA1	2.74e-04	883	31	6	C0036341
Disease	Colorectal Carcinoma	ADAM29 BPIFB2 FN1 LAMA1 CD109	7.64e-04	702	31	5	C0009402
Disease	Malignant neoplasm of breast	LAMA2 FN1 TTC3 VPS39 MIF CD109	7.73e-04	1074	31	6	C0006142
Disease	Crohn Disease	FN1 SLC22A5	1.27e-03	50	31	2	C0010346
Disease	peripheral arterial disease	MAPK10 CHRNA3	1.48e-03	54	31	2	EFO_0004265
Disease	Mammary Neoplasms, Human	FN1 VPS39 MIF CD109	2.13e-03	525	31	4	C1257931
Disease	Mammary Carcinoma, Human	FN1 VPS39 MIF CD109	2.13e-03	525	31	4	C4704874
Disease	Mammary Neoplasms	FN1 VPS39 MIF CD109	2.16e-03	527	31	4	C1458155
Disease	Alcohol abuse	FN1 CHRNA3	2.26e-03	67	31	2	C0085762
Disease	Breast Carcinoma	FN1 VPS39 MIF CD109	2.33e-03	538	31	4	C0678222
Disease	creatinine measurement	LAMA2 USP10 FAP NMRK2 SLC22A5	3.54e-03	995	31	5	EFO_0004518
Disease	psoriatic arthritis	FAP SLC22A5	3.78e-03	87	31	2	EFO_0003778

Protein segments in the cluster

Peptide	Gene	Start	Entry
EIVVVIDNYLYIRYE	ADAM29	201	Q9UKF5
EIYPDITYSLYIRRL	CHRNA3	226	P32297
RYFILPYVIYRLNIT	ALG10B	416	Q5I7T1
IAITSDYIPRFVYEY	ANO3	831	Q9BYT9
RYVAIYDPLRYSVKT	OR5M11	121	Q96RB7
TPYVVTRYYRAPEVI	MAPK10	221	P53779
VQSYVTLRVPLYVSY	FREM2	2666	Q5SZK8
DRYVAICKPLYYVVI	OR4K5	121	Q8NGD3
IDPIVTRRYYYSVKD	LAMA2	266	P24043
ERLRISPDRVYINYY	MIF	86	P14174
YVVGQTPVYVPYEIR	NFASC	786	O94856
VYTYIQSRFYRSPEV	DYRK4	261	Q9NR20
IYTDITYSFYIRRLP	CHRNA6	226	Q15825
IVDYYEPRRQAVRSY	CD109	1381	Q6YHK3
RYETRYIYGPIESTI	CPA3	341	P15088
VAYDLVYYVRVTVPG	FCGBP	1366	Q9Y6R7
RVAYDLVYYVRVTVP	FCGBP	2566	Q9Y6R7
LRVAYDLVYYVRVTV	FCGBP	3766	Q9Y6R7
APAVTVRYYRITYGE	FN1	1561	P02751
IAVDRYVTIFYALRY	MC5R	136	P33032
VYVYTAELYPTVVRN	SLC22A5	446	O76082
IVVTVYYVPCIFIYL	OR10G2	251	Q8NGC3
VDLYSRRYFLTVPYE	NMRK2	111	Q9NPI5
YRLYVIYKVPQVRVL	SNRPA1	131	P09661
PIVTRRYYYSIKDIS	LAMA1	251	P25391
NVIRDPIERLVSYYY	HS2ST1	161	Q7LGA3
AKRYTRRPLVVVYYS	PDIA4	406	P13667
YVAPEIFVYEGYVVI	BPIFB2	436	Q8N4F0
VVRIFIIDTTYPAYV	FAP	261	Q12884
YRLVTYIFVYENPIS	RHBDD2	61	Q6NTF9
RFDIAIIYYTRAIEY	TTC3	246	P53804
IIYYTRAIEYRPENY	TTC3	251	P53804
PTAERTAYLLYYRRV	USP10	781	Q14694
RIYVYVTSYDPLRIY	TTLL4	766	Q14679
YIIAVLPRYVEIRTF	VPS39	256	Q96JC1