Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionN-succinyltransferase activity

ALAS1 ALAS2

7.99e-0521792GO:0016749
GeneOntologyMolecularFunction5-aminolevulinate synthase activity

ALAS1 ALAS2

7.99e-0521792GO:0003870
GeneOntologyBiologicalProcessporphyrin-containing compound metabolic process

CYP1A2 SPTB IREB2 ALAS1 ALAS2 ABCC2

1.77e-05631796GO:0006778
GeneOntologyBiologicalProcesstetrapyrrole metabolic process

CYP1A2 SPTB IREB2 ALAS1 ALAS2 ABCC2

4.13e-05731796GO:0033013
GeneOntologyBiologicalProcessprotoporphyrinogen IX biosynthetic process

IREB2 ALAS1 ALAS2

5.20e-0591793GO:0006782
GeneOntologyBiologicalProcesskidney morphogenesis

FAT4 FRAS1 KIF26B LRRK2 LAMA5 PTCH1 KLHL3

5.24e-051111797GO:0060993
GeneOntologyCellularComponentgrowth cone

HDAC5 COPA RASGRF1 PCLO LRRK2 PTCH1 NDRG2 GDPD5 PTPRS LRP1 NIN

1.05e-0524518211GO:0030426
GeneOntologyCellularComponentaxon

CAD HDAC5 COPA RASGRF1 PPFIA2 PCLO SPTBN1 LRRK2 IREB2 GRIK5 PTCH1 NDRG2 SEPTIN8 GDPD5 CADM1 PTPRS SCN4A LRP1 AFDN LRRC7 DYNC1H1 NIN

1.07e-0589118222GO:0030424
GeneOntologyCellularComponentsite of polarized growth

HDAC5 COPA RASGRF1 PCLO LRRK2 PTCH1 NDRG2 GDPD5 PTPRS LRP1 NIN

1.42e-0525318211GO:0030427
GeneOntologyCellularComponentdistal axon

CAD HDAC5 COPA RASGRF1 PCLO LRRK2 GRIK5 PTCH1 NDRG2 GDPD5 PTPRS LRP1 NIN

1.19e-0443518213GO:0150034
GeneOntologyCellularComponentcytoplasmic side of mitochondrial outer membrane

LRRK2 BECN1

2.25e-0431822GO:0032473
GeneOntologyCellularComponentbasal ectoplasmic specialization

GSN KIAA1210

2.25e-0431822GO:0061832
GeneOntologyCellularComponentaxonal growth cone

HDAC5 PTCH1 LRP1 NIN

6.27e-04451824GO:0044295
DomainAA_TRANSFER_CLASS_2

SPTLC3 ALAS1 ALAS2

1.78e-0561823PS00599
DomainCPSASE_2

CAD ACACA MCCC1

1.78e-0561823PS00867
DomainAminotrans_II_pyridoxalP_BS

SPTLC3 ALAS1 ALAS2

1.78e-0561823IPR001917
DomainCbamoylP_synth_lsu-like_ATP-bd

CAD ACACA MCCC1

3.10e-0571823IPR005479
DomainBC-like_N

CAD ACACA MCCC1

3.10e-0571823IPR005481
DomainCPSase_L_D2

CAD ACACA MCCC1

3.10e-0571823PF02786
DomainBiotin_carb_N

CAD ACACA MCCC1

3.10e-0571823PF00289
DomainPreseq_ALAS

ALAS1 ALAS2

9.44e-0521822PF09029
Domain4pyrrol_synth_NH2levulA_synth

ALAS1 ALAS2

9.44e-0521822IPR010961
Domain5aminolev_synth_preseq

ALAS1 ALAS2

9.44e-0521822IPR015118
DomainEGF

FAT4 FRAS1 LAMA5 SVEP1 STAB1 FAT1 CELSR1 WIF1 LRP1 LRP6

1.06e-0423518210SM00181
DomainGrowth_fac_rcpt_

FAT4 FRAS1 LAMA5 SVEP1 STAB1 FAT1 CELSR1 LRP1

1.48e-041561828IPR009030
DomainEGF-like_dom

FAT4 FRAS1 LAMA5 SVEP1 STAB1 FAT1 CELSR1 WIF1 LRP1 LRP6

1.71e-0424918210IPR000742
DomainEGF

SVEP1 STAB1 FAT1 CELSR1 WIF1 LRP1 LRP6

2.37e-041261827PF00008
Domain-

CAD ACACA MCCC1

2.42e-041318233.40.50.20
DomainATP_GRASP

CAD ACACA MCCC1

3.06e-04141823PS50975
DomainATP-grasp

CAD ACACA MCCC1

3.06e-04141823IPR011761
DomainPreATP-grasp_dom

CAD ACACA MCCC1

3.06e-04141823IPR016185
Domain-

CAD ACACA MCCC1

3.80e-041518233.30.1490.20
DomainLAM_G_DOMAIN

FAT4 LAMA5 FAT1 CELSR1

4.97e-04381824PS50025
DomainSpectrin_bsu

SPTB SPTBN1

5.59e-0441822IPR016343
DomainAminotran_1_2

SPTLC3 ALAS1 ALAS2

5.60e-04171823PF00155
DomainAminotransferase_I/II

SPTLC3 ALAS1 ALAS2

5.60e-04171823IPR004839
DomainLaminin_G_2

FAT4 LAMA5 FAT1 CELSR1

6.06e-04401824PF02210
DomainATP_grasp_subdomain_1

CAD ACACA MCCC1

6.67e-04181823IPR013815
Domain-

CAD ACACA MCCC1

6.67e-041818233.30.470.20
DomainLamG

FAT4 LAMA5 FAT1 CELSR1

8.74e-04441824SM00282
DomainEGF_1

FAT4 LAMA5 SVEP1 STAB1 FAT1 CELSR1 WIF1 LRP1 LRP6

9.12e-042551829PS00022
DomainBiotin_BS

ACACA MCCC1

9.26e-0451822IPR001882
DomainBiotin_COase_C

ACACA MCCC1

9.26e-0451822IPR005482
DomainBC

ACACA MCCC1

9.26e-0451822PS50979
DomainBiotin_carb_C

ACACA MCCC1

9.26e-0451822SM00878
DomainBiotin_carb_C

ACACA MCCC1

9.26e-0451822PF02785
DomainBiotin_carboxylation_dom

ACACA MCCC1

9.26e-0451822IPR011764
DomainCPSASE_1

CAD ACACA

9.26e-0451822PS00866
DomainBIOTIN

ACACA MCCC1

9.26e-0451822PS00188
DomainEGF-like_CS

FAT4 LAMA5 SVEP1 STAB1 FAT1 CELSR1 WIF1 LRP1 LRP6

1.07e-032611829IPR013032
DomainEGF_2

FAT4 LAMA5 SVEP1 STAB1 FAT1 CELSR1 WIF1 LRP1 LRP6

1.19e-032651829PS01186
DomainEGF_CA

FAT4 SVEP1 STAB1 FAT1 CELSR1 LRP1

1.25e-031221826SM00179
DomainEGF-like_Ca-bd_dom

FAT4 SVEP1 STAB1 FAT1 CELSR1 LRP1

1.36e-031241826IPR001881
DomainRudment_hybrid_motif

ACACA MCCC1

1.38e-0361822IPR011054
Domain26S_Psome_P45

PSMC1 PSMC5

1.38e-0361822IPR005937
Pubmed

Functional proteomics mapping of a human signaling pathway.

NPR1 VWF MAN2B1 SPTBN1 LAMA5 CBX4 PRDM4 SVEP1 DDX3X TINAGL1 ANKRD13A MTMR11 CADM1 SF3B1 LRP1 AFDN PITPNB DIAPH3 HERC1 DYNC1H1

6.16e-115911842015231748
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 MAN2B1 ACACA TMEM94 POLR2A NOB1 LAMA5 EXTL3 ATG2A PTCH1 ANKHD1 BIRC6 RYR1 TINAGL1 ORC1 GDPD5 FAT1 CELSR1 TULP4 SH3TC1 PTPRS ARHGAP44 HERC1 DYNC1H1

5.29e-0911051842435748872
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

SECISBP2L AAMP HDAC5 COPA SEPTIN9 POLR2A NOB1 MSH5 ATG2A WDR54 LIN9 DDX3X CHUK ANKRD13A SEPTIN8 ZC3H7A EIF5B PRKAR1B PRKCI DIAPH3 BECN1 CNOT2 ANKS3

7.83e-0910381842326673895
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 ACACA KIF26B SEPTIN9 PPFIA2 TTC21A PCLO POLR2A COQ8B PSMC1 ESX1 GRIK5 ECPAS BIRC6 RYR1 DENND4B LRRC7 DYNC1H1 FBXO34

1.58e-087361841929676528
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FAT4 CAD ACACA COPA STRBP POLR2A SPTBN1 PSMC1 LAMA5 ECPAS DDX3X DMAP1 ADGB SF3B1 RGS6 CDC16 PSPC1 STAG3 DYNC1H1

2.32e-087541841935906200
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CAD MAN2B1 ACACA COPA STRBP SEPTIN9 PSMC1 LAMA5 GBE1 PSMC5 ERMP1 ANKHD1 BIRC6 DDX3X DMAP1 FAT1 SF3B1 EIF5B C3 PRKCI DIAPH3 CPSF3 ADPGK DYNC1H1 ALPI

2.60e-0812971842533545068
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

CAD COPA POLR2A PSMC1 PSMC5 DDX3X SF3B1 FAF2 DYNC1H1

8.21e-08144184935681168
Pubmed

Network organization of the human autophagy system.

RPL22 ACACA COPA SEPTIN9 PSMC1 PSMC5 ATG2A ECPAS CAMKK2 EIF5B PRKCI PRMT7 RASSF4 BECN1

1.01e-074371841420562859
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

RPL22 CAD COPA POLR2A RPS15A PSMC5 ANKHD1 DDX3X ZC3H7A SF3B1 FAF2 EIF5B C3 PSPC1 BECN1 DYNC1H1

1.51e-076011841633658012
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL22 RALGAPA1 CAD VWF COPA SEPTIN9 PPFIA2 TTC21A PCLO SPTB SPTBN1 RPS15A PSMC1 ARHGEF12 GSN SEPTIN8 SF3B1 PTPRS ARHGAP44 OSBPL10 AFDN LRRC7 ABLIM2 PSPC1 DYNC1H1

1.69e-0714311842537142655
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CAD ACACA COPA STRBP SEPTIN9 POLR2A RPS15A PSMC1 PSMC5 GRIK5 ANKHD1 BIRC6 DDX3X PGM3 FAF2 PRKCI DYNC1H1

2.41e-077041841729955894
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RALGAPA1 CAD COPA SEPTIN9 SPTBN1 RPS15A PSMC1 ARHGEF12 PSMC5 ECPAS DDX3X EIF5B LRP6 AFDN LRRC7 DIAPH3 DYNC1H1

2.60e-077081841739231216
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RPL22 AAMP ACACA COPA SEPTIN9 SPTBN1 PSMC1 PSMC5 MCCC1 ECPAS DDX3X GSN ANKRD13A CADM1 SF3B1 FAF2 NUDT1 LRP1 EIF5B OSBPL10 AFDN PITPNB PSPC1 CPSF3

2.80e-0713671842432687490
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

VWF COPA SPTB SPTBN1 DEF8 NAP1L3 PSMC1 RIPK4 EXTL3 PRDM4 DDX3X DMAP1 CHUK STAB1 DGLUCY CADM1 SF3B1 WIF1 LRP1 AFDN BECN1 CNOT2 DYNC1H1

3.63e-0712851842335914814
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

AAMP FRAS1 ACACA COPA STRBP POLR2A NOB1 ECPAS ITGAL RBM23 DDX3X SF3B1 FAF2 CDC16 PSPC1 CPSF3

4.56e-076531841633742100
Pubmed

A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release.

RPL22 POLR2A PIEZO2

5.80e-074184330037999
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP104 RALGAPA1 LAMA5 ERMP1 ATG2A ECPAS ANKHD1 DMAP1 STAB1 SEPTIN8 CAMKK2 RBM12 ANKS3 NIN

9.96e-075291841414621295
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

CAD MAN2B1 ACACA COPA SPTBN1 NOB1 PSMC1 LAMA5 PSMC5 DDX3X SF3B1 FAF2 PTPRS LRP1 FBXO34

1.07e-066131841522268729
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

RPL22 CAD ACACA COPA POLR2A RPS15A PSMC1 ANKHD1 BIRC6 DDX3X SF3B1 DIAPH3 PSPC1 DYNC1H1

1.11e-065341841435032548
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

RPL22 ACACA SPTBN1 ARHGEF12 APLP1 DDX3X GSN CHUK SF3B1 AFDN DYNC1H1

1.13e-063171841117620599
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

RPL22 CAD ACACA COPA SEPTIN9 PCLO POLR2A SPTBN1 RPS15A MCCC1 ECPAS RYR1 DDX3X GSN FAF2 EIF5B DYNC1H1

1.57e-068071841730575818
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAT4 FRAS1 NPR1 MAN2B1 COPA DIPK1A PSMC1 LAMA5 ERMP1 EXTL3 GDE1 DMXL1 DMAP1 FAT1 CELSR1 CADM1 METTL9 PTPRS LRP1 LRP6 ADPGK

1.76e-0612011842135696571
Pubmed

A cohesin-RAD21 interactome.

RPL22 CAD RPS15A PSMC1 DDX3X C3 PSPC1 PDZD2 NPAT

1.82e-06208184922145905
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAD ACACA COPA STRBP POLR2A SPTBN1 PSMC5 ECPAS ANKHD1 BIRC6 SF3B1 EIF5B AFDN CPSF3 DYNC1H1

2.33e-066531841522586326
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CAD COPA STRBP SPTBN1 NOB1 COQ8B PSMC1 GBE1 PSMC5 EXTL3 MCCC1 ECPAS PGM3 GSN CHUK ANKRD13A SF3B1 FAF2 METTL9 AASS EIF5B DYNC1H1 ALPI

2.51e-0614401842330833792
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL22 CAD ACACA COPA SEPTIN9 POLR2A SPTBN1 NOB1 RPS15A PSMC1 PSMC5 MCCC1 ANKHD1 BIRC6 ORC1 ZC3H7A SF3B1 FAF2 EIF5B AFDN CPSF3 DYNC1H1

3.18e-0613531842229467282
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RPL22 CAD ACACA COPA SEPTIN9 SPTBN1 RPS15A PSMC1 PSMC5 ECPAS ANKHD1 DDX3X GSN PHKA1 SEPTIN8 SF3B1 EIF5B AFDN PSPC1 DYNC1H1

3.37e-0611491842035446349
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RALGAPA1 SPTLC3 ACACA C11orf54 SEPTIN9 PPFIA2 TTC21A SPTB MSH5 ECPAS REEP3 GDE1 TULP4 SH3TC1 PTPRS ARHGAP44 LRP1 PRKAR1B PRKCI LRRC7 ABLIM2 SLC4A5 PDZD2

4.36e-0614891842328611215
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL22 CAD ACACA COPA PCLO POLR2A SPTBN1 RPS15A PSMC1 PSMC5 ECPAS ANKHD1 DDX3X SF3B1 FAF2 CDC16 EIF5B AFDN PRKCI PSPC1 CPSF3 DYNC1H1

7.22e-0614251842230948266
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

COPA DDX3X CDC16 DYNC1H1

7.42e-0624184433705438
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RPL22 ACACA COPA STRBP SEPTIN9 NOB1 RPS15A MCCC1 ANKHD1 GSN SEPTIN8 ZC3H7A EIF5B DIAPH3 NSMCE4A

8.05e-067241841536232890
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

HDAC5 STRBP PSMC1 ARHGEF12 BIRC6 DDX3X PHKA1 ZC3H7A NIN

8.40e-06251184929778605
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

VWF C11orf54 PPFIA2 SPTBN1 AOX1 LRRK2 ARHGEF12 LAMA5 GBE1 PSMC5 RYR1 DDX3X GSN ACE2 FAT1 SLC22A2 PRKCI DYNC1H1

8.44e-0610161841819056867
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CAD ACACA COPA POLR2A SPTBN1 PSMC1 PSMC5 ECPAS DDX3X SF3B1 FAF2 EIF5B CPSF3 DYNC1H1

8.58e-066381841433239621
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

HDAC5 COPA TMEM94 STRBP SEPTIN9 POLR2A SPTBN1 ARHGEF12 DMXL1 PHKA1 EIF5B C3

9.62e-064751841231040226
Pubmed

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.

SPTBN1 LAMA5 PSMC5 DDX3X ACE2 DYNC1H1

1.05e-0593184638245532
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

RPL22 CAD ACACA COPA RPS15A PSMC1 PSMC5 DDX3X PGM3 FAF2 NUDT1 CPSF3 DYNC1H1

1.10e-055651841333567341
Pubmed

Regulation of the anaphase-promoting complex by the COP9 signalosome.

PSMC1 PSMC5 CDC16

1.20e-059184319535905
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 HDAC5 TMEM94 SEPTIN9 ARHGEF12 CAMKK2 FAF2 DENND4B LRRC7 DYNC1H1 PDZD2

1.22e-054071841112693553
Pubmed

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.

RPL22 ACACA COPA SEPTIN9 SPTBN1 LAMA5 MCCC1 DDX3X GSN SF3B1 FAF2 DYNC1H1

1.26e-054881841231324722
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CAD SPTBN1 ARHGEF12 GRIK5 DDX3X GSN SF3B1 RGS6 PTPRS ARHGAP44 LRP1 PRKAR1B AFDN PRKCI LRRC7 DYNC1H1 MTSS2

1.59e-059631841728671696
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

CAD ACACA COPA RPS15A PSMC1 MCCC1 DDX3X PGM3 DYNC1H1

1.59e-05272184925315684
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MAN2B1 COPA SPTBN1 GBE1 BIRC6 SF3B1 EIF5B C3 PSPC1 DYNC1H1

1.65e-053441841030333137
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

CAD ACACA COPA RPS15A PSMC1 PSMC5 MCCC1 PGM3 FAF2 DYNC1H1

1.65e-053441841036282215
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

CAD NOB1 COQ8B BIRC6 DDX3X PHKA1 CELSR1 FAF2 AASS LRP1 CPSF3 CNOT2 ADPGK DYNC1H1

1.92e-056861841428380382
Pubmed

Physiological and pathophysiological characteristics of ataxin-3 isoforms.

CAD ACACA COPA RPS15A PSMC1 PSMC5 SF3B1 FAF2 DYNC1H1

2.06e-05281184930455355
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RPL22 CAD ERCC5 ACACA COPA SEPTIN9 POLR2A SPTBN1 NOB1 RPS15A PSMC1 ANKHD1 BIRC6 DDX3X GSN SF3B1 FAF2 EIF5B DIAPH3 PSPC1 DYNC1H1

2.12e-0514151842128515276
Pubmed

Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.

SPTBN1 DDX3X LRRC7

2.33e-0511184339256359
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

FRAS1 CAD POLR2A SPTBN1 LAMA5 TINAGL1 LRP1 PSPC1

2.35e-05219184831353912
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

ACACA DEF8 LAMA5 IREB2 BIRC6 GSN TULP4 EIF5B ALPI NIN

2.60e-053631841014691545
Pubmed

Metabolism of activated complement component C3 is mediated by the low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor.

LRP1 C3

2.78e-052184210608878
Pubmed

DDX3 directly facilitates IKKα activation and regulates downstream signalling pathways.

DDX3X CHUK

2.78e-052184230341167
Pubmed

The complex role of Wnt ligands in type 2 diabetes mellitus and related complications.

WIF1 LRP6

2.78e-052184234042263
Pubmed

Investigating the role of NPR1 in dilated cardiomyopathy and its potential as a therapeutic target for glucocorticoid therapy.

RPL22 NPR1

2.78e-052184238026943
Pubmed

Leucine-rich repeat kinase-2 deficiency protected against cardiac remodelling in mice via regulating autophagy formation and degradation.

LRRK2 BECN1

2.78e-052184235499056
Pubmed

Low density lipoprotein receptor related protein 1 and 6 gene variants and ischaemic stroke risk.

LRP1 LRP6

2.78e-052184226031789
Pubmed

Structure of a mouse erythroid 5-aminolevulinate synthase gene and mapping of erythroid-specific DNAse I hypersensitive sites.

ALAS1 ALAS2

2.78e-05218422780318
Pubmed

Two different genes encode delta-aminolevulinate synthase in humans: nucleotide sequences of cDNAs for the housekeeping and erythroid genes.

ALAS1 ALAS2

2.78e-05218422263504
Pubmed

Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.

LRRK2 LRP6

2.78e-052184227013965
Pubmed

The solution structure and heme binding of the presequence of murine 5-aminolevulinate synthase.

ALAS1 ALAS2

2.78e-052184211566198
Pubmed

Serine 254 enhances an induced fit mechanism in murine 5-aminolevulinate synthase.

ALAS1 ALAS2

2.78e-052184219917609
Pubmed

Effect of urban traffic, individual habits, and genetic polymorphisms on background urinary 1-hydroxypyrene excretion.

CYP1A2 GSTT1

2.78e-052184216406813
Pubmed

Dynamic Interaction of Stress Granules, DDX3X, and IKK-α Mediates Multiple Functions in Hepatitis C Virus Infection.

DDX3X CHUK

2.78e-052184225740981
Pubmed

Regulation of the 26S proteasome by adenovirus E1A.

PSMC1 PSMC5

2.78e-052184210970867
Pubmed

Human delta-aminolevulinate synthase: assignment of the housekeeping gene to 3p21 and the erythroid-specific gene to the X chromosome.

ALAS1 ALAS2

2.78e-05218422347585
Pubmed

Nectin-2 and DDX3 are biomarkers for metastasis and poor prognosis of squamous cell/adenosquamous carcinomas and adenocarcinoma of gallbladder.

DDX3X CADM1

2.78e-052184223330003
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RPL22 COPA SEPTIN9 SPTBN1 PSMC5 ERMP1 ECPAS ANKHD1 DDX3X SF3B1 AFDN C3 PSPC1 DYNC1H1

2.84e-057111841433022573
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

ERCC5 SPTBN1 PSMC1 ECPAS DMAP1 CPSF3 ALPI NSMCE4A

2.85e-05225184825277244
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

RPL22 PCLO SPTB SPTBN1 PSMC5 GRIK5 MCCC1 NDRG2 DDX3X GSN SEPTIN8 LRRC7 DYNC1H1

2.95e-056211841322794259
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

RPL22 MAN2B1 ACACA COPA TTC21A RPS15A LAMA5 GBE1 CBX4 MCCC1 DDX3X TINAGL1 DGLUCY FAT1 RBM12 FAF2 METTL9 LRP1 ALAS1 PSPC1 ADPGK

3.06e-0514511842130550785
Pubmed

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.

RPL22 CEP104 ACACA COPA SEPTIN9 SPTB ACE2 FAF2 CDC16 C3 FBXO34

3.26e-054531841127113764
Pubmed

Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.

RPS15A PSMC1 PSMC5 DDX3X FAF2

3.60e-0570184521726808
Pubmed

Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.

SEPTIN9 SPTBN1 PSMC1 PSMC5 RBM23 DDX3X SEPTIN8

3.60e-05170184716159877
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RPL22 CAD KCNH7 ACACA SEPTIN9 PPFIA2 PCLO SPTBN1 PSMC1 MCCC1 BIRC6 SEPTIN8 SF3B1 CDC16 PRKAR1B AFDN LRRC7 CNOT2

3.82e-0511391841836417873
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RALGAPA1 CAD COPA POLR2A SPTBN1 PSMC1 PSMC5 BIRC6 PHKA1 MTMR11 CADM1 PTPRS LRP6 PRKCI HERC1 CPSF3 NIN

4.64e-0510491841727880917
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

RPL22 CAD ACACA SEPTIN9 SPTBN1 RPS15A DDX3X GSN SF3B1 EIF5B DYNC1H1

5.20e-054771841131300519
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

RPL22 ACACA SEPTIN9 NOB1 PSMC1 ATG2A MCCC1 ECPAS DDX3X SEPTIN8 ZC3H7A AASS AFDN DYNC1H1 NIN

5.33e-058531841528718761
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

HK3 HDAC5 COPA STRBP POLR2A ECPAS ANKHD1 LIN9 DMAP1 CHUK SF3B1 SH3TC1 LRP1 EIF5B DYNC1H1

5.62e-058571841525609649
Pubmed

Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer.

AAMP PCLO FAF2

6.33e-0515184331903119
Pubmed

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

ACACA PSMC5 DYNC1H1

6.33e-0515184318303054
Pubmed

Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2.

VWF ACE2 C3

6.33e-0515184336305765
Pubmed

FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.

STRBP PSMC1 PSMC5 DDX3X EIF5B HERC1

6.42e-05128184628027390
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

RPL22 AAMP CAD COPA NOB1 RPS15A PSMC1 ARHGEF12 PSMC5 DDX3X SF3B1 CDC16 LRP1 EIF5B PRKCI CPSF3

6.44e-059711841633306668
Pubmed

Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.

STRBP POLR2A PSMC5 MCCC1 ANKHD1 SF3B1

6.71e-05129184628973437
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

RPL22 CAD COPA SPTBN1 RPS15A PSMC1 DDX3X GSN EIF5B PSPC1 DYNC1H1 ALPI

6.72e-055801841235676659
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PDE4C ERCC5 ACACA COPA SEPTIN9 POLR2A SPTBN1 ECPAS SF3B1 ABCB9 EIF5B AFDN ALPI IQCK

7.06e-057741841415302935
Pubmed

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

RPL22 CAD COPA RPS15A PSMC1 PSMC5 FAF2 DYNC1H1

7.08e-05256184835777956
Pubmed

Putting an 'End' to HIV mRNAs: capping and polyadenylation as potential therapeutic targets.

POLR2A DDX3X CPSF3

7.75e-0516184324330569
Pubmed

The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development.

VWF GYPA ALAS2

7.75e-0516184326527618
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SECISBP2L AAMP HDAC5 TTC21A PSMC5 REEP3 PGM3 GSN ANKRD13A METTL9 CDC16 ARHGAP44 EIF5B AFDN C3 PRKCI CNOT2 ANKS3 DYNC1H1

8.10e-0513211841927173435
Pubmed

Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients.

SLC22A2 ABCC2

8.32e-053184227590272
Pubmed

Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-α.

PTCH1 C3

8.32e-053184235725556
Pubmed

Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3.

SLC6A18 ACE2

8.32e-053184219478081
Pubmed

The clearance mechanism of chilled blood platelets.

VWF C3

8.32e-053184212526796
Pubmed

CircFAT1 promotes hepatocellular carcinoma progression via miR-30a-5p/REEP3 pathway.

REEP3 FAT1

8.32e-053184233179443
Pubmed

Expression of RA175 mRNA, a new member of the immunoglobulin superfamily, in developing mouse brain.

PTCH1 CADM1

8.32e-053184211711859
Pubmed

RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity.

DMAP1 RGS6

8.32e-053184214734556
Pubmed

Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity.

PSMC1 PSMC5

8.32e-053184220424172
Pubmed

Influence of polymorphism of GSTM1 gene on association between glycophorin a mutant frequency and urinary PAH metabolites in incineration workers.

GSTT1 GYPA

8.32e-053184211936216
Pubmed

The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.

SPTB SPTBN1

8.32e-05318428479293
InteractionC2CD4B interactions

FAT4 FRAS1 FAT1 CELSR1 SCN4A HERC1

2.41e-06441796int:C2CD4B
InteractionCMA1 interactions

FAT4 FRAS1 FAT1 CELSR1 MTMR11 LRP6

3.15e-06461796int:CMA1
InteractionTOP3B interactions

RPL22 FRAS1 CAD MAN2B1 ACACA TMEM94 POLR2A SPTB NOB1 LAMA5 IREB2 EXTL3 ATG2A PTCH1 ANKHD1 BIRC6 RYR1 DDX3X TINAGL1 ORC1 GDPD5 ZC3H7A FAT1 CELSR1 TULP4 SH3TC1 PTPRS ARHGAP44 HERC1 CNOT2 DYNC1H1

5.63e-06147017931int:TOP3B
InteractionCOPB1 interactions

CAD HDAC5 ACACA COPA SPTBN1 PSMC1 RIPK4 ACE2 ZC3H7A SF3B1 NUDT1 EIF5B

1.32e-0529417912int:COPB1
InteractionFGF11 interactions

RPL22 STRBP PSMC1 PSMC5 ANKHD1 DDX3X EIF5B PRKAR1B HERC1

2.18e-051701799int:FGF11
InteractionKCNA3 interactions

RALGAPA1 CAD COPA SEPTIN9 SPTBN1 LRRK2 RPS15A PSMC1 ARHGEF12 PSMC5 ECPAS RYR1 DDX3X ORC1 FAF2 EIF5B LRP6 AFDN LRRC7 DIAPH3 DYNC1H1

3.24e-0587117921int:KCNA3
InteractionPSMD1 interactions

CAD HDAC5 ACACA RPS15A PSMC1 KLF15 PSMC5 PTCH1 ECPAS ACE2 RBM12 PTPRS AFDN PRKCI

4.27e-0544217914int:PSMD1
CoexpressionGSE20715_0H_VS_24H_OZONE_LUNG_DN

LRRK2 KLF15 SVEP1 GSN TINAGL1 TULP4 EIF5B C3 ALAS1

1.16e-052001829M4367
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

VWF SPTBN1 PTCH1 NDRG2 LIN9 GSN STAB1 CADM1 C3 ALAS2 SLC4A5 MTSS2

4.22e-0542218212M7396
CoexpressionTRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL

NPR1 SPTBN1 AOX1 SVEP1 PGM3 GSN PTPRS LRP1 C3 ITM2A

4.49e-0529618210M41675
CoexpressionGSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP

ARHGEF12 DMXL1 ZC3H7A PIEZO2 SF3B1 HERC1 STAG3

4.99e-051371827M6346
CoexpressionHARALAMBIEVA_PBMC_M_M_R_II_AGE_11_22YO_VACCINATED_VS_UNVACCINATED_7YR_DN

RPL22 FAT4 SLC29A3 VWF MAN2B1 RASGRF1 DEF8 GSN STAB1 KLHL3 CELSR1 FAM153A SH3TC1 LRP1 SLC37A2 IQCK

6.31e-0574018216M41202
CoexpressionSWEET_LUNG_CANCER_KRAS_DN

VWF SPTBN1 PTCH1 NDRG2 LIN9 GSN STAB1 CADM1 C3 ALAS2 SLC4A5 MTSS2

6.86e-0544418212MM1051
CoexpressionGSE22886_UNSTIM_VS_IL15_STIM_NKCELL_UP

FRAS1 HDAC5 LAMA5 CBX4 ATG2A KLHL3 DGLUCY PSPC1

7.14e-051961828M4532
CoexpressionGSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP

HDAC5 RPS15A CBX4 ATG2A PRDM4 KLHL3 DGLUCY PSPC1

7.14e-051961828M4530
CoexpressionGSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP

ERCC5 PSMC5 CBX4 SH3TC1 DENND4B AFDN RASSF4 NSMCE4A

7.94e-051991828M9964
CoexpressionGSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_UP

CAD NOB1 PSMC1 ORC1 CDC16 SCN4A ALAS1 NPAT

8.22e-052001828M9474
CoexpressionGSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN

RPS15A KLF15 IREB2 DMAP1 AASS PRKCI ALAS2 ADPGK

8.22e-052001828M7055
CoexpressionGSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN

RPL22 MAN2B1 SEPTIN9 MSH5 GSN STAB1 AASS C3

8.22e-052001828M5104
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SECISBP2L SPTLC3 ACACA MCCC1 CELSR1 CADM1 ARHGAP44 LRP6 PRKCI PDZD2

1.12e-08199184105f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPTBN1 LAMA5 CAPN13 CADM1 ARHGAP44 OSBPL10 AFDN DIAPH3 PDZD2

1.02e-07190184930b50d183d7649146eb1e79b47ba897355f1998a
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACACA LRRK2 CELSR1 CADM1 ARHGAP44 WIF1 LRP6 B4GALNT3 PDZD2

1.07e-071911849e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ACACA LRRK2 CELSR1 CADM1 ARHGAP44 WIF1 PRKCI B4GALNT3 PDZD2

1.12e-071921849499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ACACA LRRK2 CELSR1 CADM1 ARHGAP44 LRP6 PRKCI B4GALNT3 PDZD2

1.12e-071921849efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPTLC3 ACACA RASGRF1 LRRK2 MCCC1 CADM1 ARHGAP44 PRKCI PDZD2

1.52e-071991849725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PDE4C ACACA LAMA5 PGM3 DMXL1 LRP6 DIAPH3 CHAC1

1.66e-07145184880684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

PDE4C ACACA LAMA5 PGM3 DMXL1 LRP6 DIAPH3 CHAC1

1.66e-071451848cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

HDAC5 KIF26B SPTB PTCH1 ECPAS SEPTIN8 PTPRS ABLIM2

5.11e-071681848c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPTBN1 LAMA5 CAPN13 CADM1 ARHGAP44 AFDN DIAPH3 PDZD2

1.02e-06184184857c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

ACACA RASGRF1 LRRK2 CADM1 ARHGAP44 WIF1 C3 PDZD2

1.02e-061841848369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPTBN1 LAMA5 CAPN13 CADM1 ARHGAP44 AFDN DIAPH3 PDZD2

1.02e-061841848d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 TTC21A GBE1 NDRG2 RNASE10 C3 ALAS1 HSD17B1

1.06e-06185184853854a9ec87c24c360541c83d86d8fafb303ad58
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 TTC21A GBE1 NDRG2 RNASE10 C3 ALAS1 HSD17B1

1.06e-061851848a61fc7a3700a1efcf640bef7680c0443ee148a46
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SECISBP2L STRBP LRRK2 CELSR1 CADM1 ARHGAP44 WIF1 PRKCI

1.10e-0618618482ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 SPTLC3 AOX1 CELSR1 SLC22A2 ABCC2 RASSF4 PDZD2

1.10e-061861848b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SECISBP2L FRAS1 LAMA5 CELSR1 CADM1 ARHGAP44 WIF1 DIAPH3

1.15e-0618718484ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SECISBP2L FRAS1 STRBP LRRK2 CADM1 ARHGAP44 WIF1 PRKCI

1.29e-0619018488aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

SECISBP2L ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1 PDZD2

1.35e-061911848a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

SECISBP2L LRRK2 LAMA5 CADM1 ARHGAP44 WIF1 AFDN PRKCI

1.35e-061911848d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

SECISBP2L ACACA RASGRF1 PCLO LRRK2 MCCC1 WIF1 PRKCI

1.40e-06192184806013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L ACACA RASGRF1 LRRK2 CADM1 WIF1 C3 PRKCI

1.45e-061931848043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1 C3 PDZD2

1.45e-061931848738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellIPF-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

NPR1 AOX1 GBE1 SVEP1 GSN LRP1 C3 ITM2A

1.51e-061941848da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L SPTLC3 RASGRF1 LRRK2 CADM1 WIF1 C3 PDZD2

1.63e-0619618487e5addaa844e66f8160e05858c341866a80aed23
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SECISBP2L SPTLC3 ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1

1.76e-0619818482e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SECISBP2L SPTLC3 ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1

1.76e-061981848f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACACA STRBP MCCC1 CELSR1 CADM1 ARHGAP44 PRKCI PDZD2

1.83e-0619918485cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L LRRK2 MCCC1 CADM1 WIF1 LRP6 C3 PDZD2

1.83e-0619918482dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAN2B1 HK3 GSN STAB1 SH3TC1 SLC37A2 C3 RASSF4

1.90e-06200184874ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCelldroplet-Heart-nan-24m-Hematologic-red_blood_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAD PDE4C HEXD GYPA ALAS2

3.49e-0656184555337ff90621e1fea4d747ae2559c0fa61b38dce
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR54 PTCH1 ITGAL SLC7A14 RYR1 OSGIN2 ADPGK

4.90e-0616118473f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB ARHGEF12 APLP1 GYPA LRP1 ALAS2 ABLIM2

4.90e-06161184760f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCellSmart-seq2-blood_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HK3 LRRK2 STAB1 DENND4B LRP1 ALAS2 RASSF4

6.73e-0616918470ee74cc97a2db9cc16dc73424f74747afe13af90
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

VWF SPTBN1 ARHGEF12 LAMA5 CADM1 ARHGAP44 PDZD2

7.00e-061701847e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCelldroplet-Spleen-SPLEEN|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 TINAGL1 SEPTIN8 METTL9 GYPA C3 ALAS2

7.55e-061721847d32731a56e113ff0ef7167b23959d69baf2068f9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 AOX1 ACE2 RGN ABCC2 RASSF4 PDZD2

8.77e-0617618471595dbeee336a81e581325d63208ec6262664ee9
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KLF15 NDRG2 SVEP1 GSN GSTT1 LRP1 C3

1.05e-051811847091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ACACA GDE1 CADM1 ARHGAP44 WIF1 C3 B4GALNT3

1.05e-051811847576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SPTB ARHGEF12 ATG2A RGS6 GYPA ALAS2 HERC1

1.09e-0518218470c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRAS1 AOX1 ACE2 FAT1 SLC22A2 OSBPL10 ABCC2

1.13e-0518318476878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 KIF26B PPFIA2 PCLO FAT1 PIEZO2

1.17e-0518418472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 KIF26B PPFIA2 PCLO FAT1 PIEZO2

1.17e-0518418472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

SPTBN1 LAMA5 CADM1 ARHGAP44 AFDN DIAPH3 PDZD2

1.17e-051841847561592edc3083fad41b91811151b442207c65dd9
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

AOX1 LRRK2 ACE2 FAT1 SLC22A2 OSBPL10 RASSF4

1.17e-05184184751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 KIF26B PPFIA2 PCLO FAT1 PIEZO2

1.17e-051841847ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPTBN1 LAMA5 CADM1 ARHGAP44 AFDN DIAPH3 PDZD2

1.21e-0518518471c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A2 KLF15 SVEP1 GSTT1 ARHGAP44 LRP1 C3

1.21e-051851847eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A2 KLF15 SVEP1 GSTT1 ARHGAP44 LRP1 C3

1.21e-051851847ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCelldroplet-Marrow-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 GBE1 SLC7A14 GSN C3 ALAS1 ADPGK

1.21e-0518518473dcafbd02b65a2befbb6e6288cb2591e721cddb6
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A2 KLF15 SVEP1 GSTT1 ARHGAP44 LRP1 C3

1.21e-051851847f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NPR1 VWF STAB1 TINAGL1 GDPD5 SH3TC1 ITM2A

1.30e-05187184703de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE4C RASGRF1 C11orf54 LRRK2 LRRC52 CADM1 WIF1

1.30e-0518718477c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

SPTBN1 LAMA5 CADM1 ARHGAP44 AFDN DIAPH3 PDZD2

1.30e-05187184777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEPTIN9 ANKRD13A CADM1 ARHGAP44 WIF1 AFDN B4GALNT3

1.35e-05188184743a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ACACA RASGRF1 PCLO LRRK2 AASS ARHGAP44 C3

1.35e-051881847ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA5 CELSR1 CADM1 ARHGAP44 WIF1 AFDN DIAPH3

1.35e-051881847eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

SPTBN1 LAMA5 CADM1 ARHGAP44 AFDN DIAPH3 PDZD2

1.39e-0518918475a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF26B AOX1 PTCH1 SVEP1 PIEZO2 PTPRS LRP1

1.39e-0518918472a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

AOX1 FAT1 SLC22A2 OSBPL10 C3 ABCC2 RASSF4

1.39e-0518918470be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACACA RASGRF1 LRRK2 CADM1 ARHGAP44 WIF1 C3

1.44e-05190184727a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 CELSR1 SLC22A2 OSBPL10 ABCC2 RASSF4 PDZD2

1.49e-0519118471c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L RPL22 RASGRF1 LRRK2 RPS15A CADM1 WIF1

1.49e-0519118472b0d55a8e1b4ce862dd038f8e0429e8428fb8aba
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 CELSR1 SLC22A2 OSBPL10 ABCC2 RASSF4 PDZD2

1.49e-0519118473c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

ACACA RASGRF1 PCLO LRRK2 CADM1 ARHGAP44 C3

1.49e-051911847276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SECISBP2L PPFIA2 APLP1 REEP3 SLC7A14 SEPTIN8 PIEZO2

1.54e-0519218478dc3016601148243196e925641c9507e9d58c9e0
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 NPR1 ARHGEF12 TBC1D20 RGS6 AFDN ITM2A

1.54e-051921847c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1 PDZD2

1.54e-05192184758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SECISBP2L ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1

1.60e-051931847f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellfacs-Lung-EPCAM-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 NDRG2 SVEP1 GSN GSTT1 LRP1 C3

1.60e-051931847b9ac74357435f2f24aaede62b2a1d31b5d96a12c
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SECISBP2L ACACA RASGRF1 LRRK2 MCCC1 CADM1 WIF1

1.60e-051931847fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellfacs-Heart-RV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF15 NDRG2 SVEP1 GSN GSTT1 LRP1 ITM2A

1.60e-05193184776f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 NPR1 VWF ARHGEF12 RGS6 AFDN ITM2A

1.60e-05193184702f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 NPR1 VWF ARHGEF12 RGS6 AFDN ITM2A

1.60e-0519318475122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACACA LRRK2 CADM1 ARHGAP44 WIF1 AFDN PDZD2

1.65e-05194184753f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SECISBP2L ACACA LRRK2 MCCC1 CADM1 WIF1 PDZD2

1.65e-05194184797534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L RASGRF1 LRRK2 MCCC1 CADM1 WIF1 C3

1.65e-05194184746266d3d9af7000dc1381b1c8e55047193cbcf94
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPR1 VWF TINAGL1 GDPD5 RGS6 SH3TC1 ITM2A

1.65e-0519418472e3a64bda7c76fd0c99e93de0215f236e8045d83
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN1 SVEP1 GSN GSTT1 LRP1 C3 ITM2A

1.65e-051941847889c6e231bdd5b59902c7d2afdc077360b1d3256
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 AOX1 APLP1 EXTL3 C3 ABLIM2 CHAC1

1.71e-051951847a52685f76eca269a7d2de8dfc317439483e233fa
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPR1 VWF TINAGL1 GDPD5 RGS6 SH3TC1 ITM2A

1.71e-051951847ca2cf2c10db1ad17aa0a2e30aa7079a7ad751ea6
ToppCellPCW_07-8.5-Endothelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPR1 VWF TINAGL1 GDPD5 RGS6 SH3TC1 ITM2A

1.71e-051951847f2cc94d5e1652203ca38bea57f37d3deec73ef04
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 AOX1 APLP1 EXTL3 C3 ABLIM2 CHAC1

1.71e-051951847224deeba2f60def6543a55bb4f5ee6c7fdab3f02
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 AOX1 SVEP1 GSN PIEZO2 LRP1 C3

1.71e-051951847f54bc4454270ff06e85596f98199372b50d0179f
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACACA LRRK2 CADM1 ARHGAP44 WIF1 AFDN PDZD2

1.71e-0519518479406866f99555198a9be311fbd65751b70f35446
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 KIF26B PTCH1 SVEP1 PIEZO2 ALX1 LRP1

1.76e-051961847a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SECISBP2L RASGRF1 LRRK2 CADM1 WIF1 LRP6 C3

1.76e-051961847754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 KIF26B PTCH1 SVEP1 PIEZO2 ALX1 LRP1

1.76e-0519618473e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NPR1 VWF STAB1 TINAGL1 GDPD5 RGS6 ITM2A

1.76e-05196184781278e696d823744267d6315c4d42799c4ea0b2c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RPL22 RASGRF1 LRRK2 RPS15A CADM1 WIF1 C3

1.76e-051961847fa42a8f8a11645fc733ce9c59c2a0599ecf2176d
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COPA SPTBN1 ARHGEF12 DDX3X SF3B1 WIF1 ITM2A

1.82e-051971847e77016d64b1cac9825fec7cfe5071f1567401187
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NPR1 VWF STAB1 TINAGL1 GDPD5 RGS6 ITM2A

1.82e-05197184788859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPA SPTBN1 ARHGEF12 DDX3X SF3B1 WIF1 ITM2A

1.82e-0519718470353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L PDE4C RASGRF1 LRRK2 CADM1 WIF1 C3

1.82e-051971847bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellASK440-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SECISBP2L ACACA RASGRF1 LRRK2 CADM1 WIF1 C3

1.82e-05197184708d5bbeb77a4152af1c783bc958afcae24667767
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SECISBP2L SPTLC3 RASGRF1 LRRK2 CADM1 WIF1 C3

1.82e-051971847fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SECISBP2L RASGRF1 APLP1 SLC7A14 GSN SEPTIN8 PIEZO2

1.82e-05197184782b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

RPL22 SPTBN1 RPS15A PTCH1 NDRG2 RGN PIEZO2

1.82e-05197184744f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH7 STRBP PPFIA2 PCLO ARHGAP44 LRRC7 HERC1

1.88e-0519818470ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPR1 VWF SPTBN1 GSN TINAGL1 ITM2A IQCK

1.94e-05199184757709dc893da8d9333830b8277a6d92e25aa8bc0
DrugBicuculline (+) [485-49-4]; Up 200; 10.8uM; PC3; HT_HG-U133A

RALGAPA1 ECPAS SVEP1 TINAGL1 CADM1 ABCB9 AASS C3 ABCC2 MTSS2

4.42e-06196183104574_UP
DrugAmiodarone

SLC6A18 CYP1A2 FRAS1 CAD MAN2B1 ACACA PPDPF SPTBN1 PSMC1 KLF15 GBE1 PSMC5 ECPAS NDRG2 GSN PHKA1 GSTT1 RGN FAT1 FAM153A RGS6 ABCB9 SLC22A2 SCN4A ALAS1 ALAS2 ABCC2 ADPGK CHAC1

6.40e-06146918329ctd:D000638
Druguroporphyrin III

CYP1A2 LPO ALAS1 ALAS2

6.82e-06161834CID000072423
DrugBAMP

NPR1 ACACA MCCC1

1.00e-0561833CID000440839
Drug2alpha-propoxy-1alpha,25-dihydroxyvitamin D3

SPTBN1 RYR1 C3

1.00e-0561833CID010062706
Drugheptacarboxylic porphyrin

CYP1A2 ALAS1 ALAS2

1.75e-0571833CID000168414
Drugnaphthol AS-D chloroacetate

VWF ITGAL PGM3 GYPA LPO ALPI

2.31e-05711836CID000160247
Drugoxothulium

CYP1A2 RASGRF1 ALAS1 ALAS2

2.64e-05221834CID000139299
DrugPhenylpropanolamine hydrochloride [154-41-6]; Down 200; 21.4uM; PC3; HT_HG-U133A

RALGAPA1 FAT4 DIPK1A EXTL3 TINAGL1 CADM1 ABCB9 IQCK MTSS2

2.74e-0519318396699_DN
DrugPicrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A

NPR1 RASGRF1 GRIK5 RYR1 ADGB RGS6 SLC22A2 RASSF4 ALPI

2.86e-0519418394260_UP
DrugDiethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; HL60; HT_HG-U133A

RALGAPA1 NPR1 RASGRF1 ARHGEF12 SLC22A2 LPO SCN4A PRKAR1B MTSS2

2.97e-0519518392394_UP
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; PC3; HT_HG-U133A

HDAC5 TMEM94 IREB2 SEPTIN8 KLHL3 CELSR1 ANKEF1 LRP6 CHAC1

3.10e-0519618397142_DN
Drugtrifluoperazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A

CEP104 PPDPF PCLO ORC1 SEPTIN8 RBM12 DENND4B PRMT7 PDZD2

3.22e-0519718391224_DN
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

ATG2A PTCH1 ABCB9 PTPRS ARHGAP44 PRKAR1B C3 HSD17B1 OSGIN2

3.22e-0519718392821_UP
DrugNorgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A

RALGAPA1 PCLO PTCH1 SVEP1 RYR1 DDX3X GSN RBM12 MTSS2

3.22e-0519718394730_UP
DrugMethoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; HL60; HT_HG-U133A

PCLO SPTB RYR1 DDX3X STAB1 GSTT1 CAMKK2 PRKAR1B MTSS2

3.22e-0519718392488_UP
DrugGanciclovir [82410-32-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A

CEP104 RALGAPA1 APLP1 GRIK5 EXTL3 GDPD5 GYPA PRKAR1B LRP6

3.35e-0519818395389_DN
DrugPyrilamine maleate [59-33-6]; Down 200; 10uM; PC3; HT_HG-U133A

CEP104 SPTLC3 TMEM94 SPTBN1 IREB2 APLP1 KLHL3 OSGIN2 CHAC1

3.35e-0519818395869_DN
DrugMelatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A

RALGAPA1 HDAC5 SEPTIN9 APLP1 ECPAS GDPD5 PTPRS PRKAR1B LRP6

3.35e-0519818395393_DN
DrugHNMPA-(AM)3; Up 200; 5uM; PC3; HG-U133A

SLC29A3 KLF15 GRIK5 NDRG2 PIEZO2 CADM1 PRKAR1B CHAC1 IQCK

3.49e-051991839583_UP
Drugethylhydrazine

CYP1A2 NPR1 LPO

4.14e-0591833CID000029062
DrugMaprotiline

SLC22A2 ABCC2 BECN1

4.14e-0591833ctd:D008376
Drugdicyclohexyl phthalate

CYP1A2 CAD HDAC5 STRBP SPTB AOX1 LRRK2 ARHGEF12 KLF15 RIPK4 GSN STAB1 GSTT1 RGN C3 PRKCI HSD17B1 BECN1 ALPI

4.66e-0583618319ctd:C036042
Drugphenylhydrazine

NPR1 SPTB SPTBN1 LPO ALAS1 ALAS2

5.24e-05821836CID000007516
Drugmannose-1-phosphate

MAN2B1 HK3 GBE1 IREB2 PGM3 PHKA1 DYNC1H1 ALPI

5.86e-051651838CID000000466
Drug2-amino-3-ketoadipate

ALAS1 ALAS2

6.43e-0521832CID000440714
Drugpregnanedione

ALAS1 ALAS2

6.43e-0521832CID000135006
DrugLY188544

PTCH1 C3

6.43e-0521832CID000126157
Diseasecancer (is_implicated_in)

LRRK2 GSTT1

3.66e-0521792DOID:162 (is_implicated_in)
Diseasecathepsin L1 measurement

MAN2B1 LRRK2 ADGB

1.16e-04161793EFO_0010619
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

2.18e-0441792DOID:0050882 (implicated_via_orthology)
Diseaseneurodegenerative disease (implicated_via_orthology)

FAT4 LRRK2 PSMC1 PTCH1 MTMR11 DYNC1H1

2.65e-041451796DOID:1289 (implicated_via_orthology)
DiseaseCOVID-19 (is_implicated_in)

GSTT1 ACE2 C3

2.69e-04211793DOID:0080600 (is_implicated_in)
Diseaseporphyria (implicated_via_orthology)

GBE1 IREB2

3.62e-0451792DOID:13268 (implicated_via_orthology)
Diseasedisease progression measurement

SLC29A3 POLR2A CELSR1 HERC1

5.22e-04611794EFO_0008336
DiseaseParatuberculosis

GSN C3

5.40e-0461792C0030524
Diseaseanemia (biomarker_via_orthology)

IREB2 ALAS2

7.53e-0471792DOID:2355 (biomarker_via_orthology)
Diseasebilirubin metabolic disorder (biomarker_via_orthology)

ALAS2 ABCC2

7.53e-0471792DOID:2741 (biomarker_via_orthology)
Diseasefasting blood insulin measurement

SLC29A3 KIF26B SPTB MCCC1

8.33e-04691794EFO_0004466
DiseaseDrug-Induced Liver Disease

CYP1A2 VWF MCCC1 GSN GSTT1 RGN AASS C3 ABCC2

8.51e-044041799C0860207
DiseaseDrug-Induced Acute Liver Injury

CYP1A2 VWF MCCC1 GSN GSTT1 RGN AASS C3 ABCC2

8.51e-044041799C3658290
DiseaseHepatitis, Toxic

CYP1A2 VWF MCCC1 GSN GSTT1 RGN AASS C3 ABCC2

8.51e-044041799C0019193
DiseaseChemically-Induced Liver Toxicity

CYP1A2 VWF MCCC1 GSN GSTT1 RGN AASS C3 ABCC2

8.51e-044041799C4279912
DiseaseChemical and Drug Induced Liver Injury

CYP1A2 VWF MCCC1 GSN GSTT1 RGN AASS C3 ABCC2

8.51e-044041799C4277682
DiseaseHepatitis, Drug-Induced

CYP1A2 VWF MCCC1 GSN GSTT1 RGN AASS C3 ABCC2

8.51e-044041799C1262760
DiseaseHereditary spherocytosis

CAD SPTB

1.00e-0381792C0037889
Diseasenon-small cell lung carcinoma

SECISBP2L CYP1A2 MSH5 PIEZO2

1.14e-03751794EFO_0003060
Diseaselysine measurement

TINAGL1 RGS6 AASS

1.47e-03371793EFO_0005002
Diseaseleptin measurement

SPTB MCCC1 ADGB PDZD2

1.51e-03811794EFO_0005000
DiseaseCarotid Circulation Transient Ischemic Attack

NDRG2 C3

1.59e-03101792C0751019
DiseaseTransient Ischemic Attack

NDRG2 C3

1.59e-03101792C0007787
DiseaseCrescendo Transient Ischemic Attacks

NDRG2 C3

1.59e-03101792C0751021
DiseaseTransient Ischemic Attack, Vertebrobasilar Circulation

NDRG2 C3

1.59e-03101792C0751020
DiseaseBrain Stem Ischemia, Transient

NDRG2 C3

1.59e-03101792C0751022
Diseasetheophylline measurement

CYP1A2 LRRK2

1.59e-03101792EFO_0021180
DiseasePosterior Circulation Transient Ischemic Attack

NDRG2 C3

1.59e-03101792C0472381
Disease1,7-dimethylurate measurement

CYP1A2 GRIK5

1.59e-03101792EFO_0021512
DiseaseTransient Ischemic Attack, Anterior Circulation

NDRG2 C3

1.59e-03101792C1527335
DiseaseTransient Cerebral Ischemia

NDRG2 C3

1.59e-03101792C0917805
DiseaseIntellectual Disability

RALGAPA1 TMEM94 DDX3X PGM3 TBC1D20 ACE2 ALKBH8 AASS DYNC1H1

1.71e-034471799C3714756
Diseaseinvasive ductal carcinoma (is_marker_for)

WIF1 PRKCI HSD17B1

1.84e-03401793DOID:3008 (is_marker_for)
Diseasepeanut allergy measurement, parental genotype effect measurement

RYR1 ADGB

1.94e-03111792EFO_0005939, EFO_0007017
DiseaseBasal cell carcinoma

ERCC5 PTCH1

1.94e-03111792C0007117
DiseaseCongenital small ears

FRAS1 ORC1 WIF1

1.98e-03411793C0152423
Diseaseoral microbiome measurement

FRAS1 GRIK5 PDZD2

2.12e-03421793EFO_0801229
DiseaseCongenital myopathy (disorder)

RYR1 SCN4A

2.32e-03121792C0270960
DiseaseSquamous cell carcinoma of esophagus

FAT4 GSTT1 FAT1 ABCC2

2.71e-03951794C0279626
Diseaseresponse to radiation, hearing loss, response to antineoplastic agent

RNASE10 LRRC7 PDZD2

2.75e-03461793EFO_0004238, GO_0009314, GO_0097327
Diseasepulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio

PTCH1 GYPA LRP1

2.93e-03471793EFO_0003892, EFO_0004713, EFO_0005671
Diseasemyocardial infarction (biomarker_via_orthology)

VWF GSN ACE2 C3 BECN1

2.99e-031601795DOID:5844 (biomarker_via_orthology)
Diseasehippocampal CA1 volume

STRBP PTCH1 FBXO34

3.11e-03481793EFO_0009394
Diseasethalamus volume change measurement

KIF26B FAT1

3.17e-03141792EFO_0021496
Diseaserevision of total hip arthroplasty

RIPK4 OSBPL10

3.17e-03141792EFO_0020973
Disease5-methyluridine (ribothymidine) measurement

PCLO PTPRS

3.17e-03141792EFO_0020013
DiseaseAnilide use measurement

MSH5 LRP1

3.65e-03151792EFO_0009938
Disease1,3,7-trimethylurate measurement

CYP1A2 FRAS1

3.65e-03151792EFO_0021172
Diseaseanemia (implicated_via_orthology)

IREB2 SLC4A5

3.65e-03151792DOID:2355 (implicated_via_orthology)
Diseaseinflammatory biomarker measurement, YKL40 measurement

PTCH1 SLC39A12 METTL9

3.69e-03511793EFO_0004869, EFO_0004872
DiseaseColorectal Carcinoma

CYP1A2 CAD HK3 ACACA PSMC5 FAT1 SH3TC1 PTPRS WIF1 LRP1 ABCC2

3.87e-0370217911C0009402
Diseasepulmonary function measurement, FEV/FEC ratio

PTCH1 GYPA LRP1

4.12e-03531793EFO_0003892, EFO_0004713
DiseaseSchizoaffective disorder-bipolar type

PCLO PTCH1

4.15e-03161792EFO_0009965
Diseasesickle cell anemia (is_implicated_in)

GSTT1 C3

4.15e-03161792DOID:10923 (is_implicated_in)
Diseasemortality

PSMC1 CADM1 PITPNB PDZD2 NIN

4.17e-031731795EFO_0004352
Diseasehepatocellular carcinoma (biomarker_via_orthology)

CAD RGN CADM1 C3

4.30e-031081794DOID:684 (biomarker_via_orthology)
DiseaseGlycogen storage disease

GBE1 PHKA1

4.69e-03171792cv:C0017919
DiseaseKuhnt-Junius degeneration (is_implicated_in)

GSTT1 C3

4.69e-03171792DOID:10873 (is_implicated_in)
Diseasediabetic neuropathy (biomarker_via_orthology)

LRRK2 BECN1

4.69e-03171792DOID:9743 (biomarker_via_orthology)
Diseasehypertrophic cardiomyopathy (is_marker_for)

ACE2 BECN1

4.69e-03171792DOID:11984 (is_marker_for)
DiseaseMHPG measurement, 5-HIAA measurement

PIEZO2 CADM1

4.69e-03171792EFO_0005132, EFO_0005133
Diseaseurate measurement, bone density

SPTLC3 FRAS1 PPFIA2 LAMA5 GBE1 RIPK4 RGS6 PRKAR1B PITPNB PDZD2

4.70e-0361917910EFO_0003923, EFO_0004531
DiseaseAlzheimer's disease (implicated_via_orthology)

PSMC5 APLP1 LRP1

5.05e-03571793DOID:10652 (implicated_via_orthology)
Diseasedrug-Induced dyskinesia, response to levodopa

EXTL3 CAPN13

5.25e-03181792EFO_0010747, EFO_1000904
Diseasekidney volume

PTCH1 GYPA

5.25e-03181792EFO_0600044
Diseaselifestyle measurement, alcohol consumption measurement

VWF GRIK5 PIEZO2 RGS6

5.37e-031151794EFO_0007878, EFO_0010724
DiseaseMalignant neoplasm of skin

PTCH1 GSTT1 GYPA

5.56e-03591793C0007114
DiseaseSkin Neoplasms

PTCH1 GSTT1 GYPA

5.56e-03591793C0037286
Diseaseinflammatory bowel disease (is_implicated_in)

GSTT1 ALPI

5.85e-03191792DOID:0050589 (is_implicated_in)
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

VWF GSTT1

5.85e-03191792DOID:9744 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
HAPSIIFMDEIDSIG

PSMC5

241

P62195
GPLEHVMETLDNESF

ALX1

26

Q15699
SQPTEDLEFHGVMRF

AFDN

31

P55196
TATADLAHPLDMFLG

ESX1

206

Q8N693
TIGVMVTASHNPEED

PGM3

56

O95394
EEFQPDLVVLSGLHM

ADPGK

251

Q9BRR6
VFEFVGEPELMDVHV

NUDT1

71

P36639
GEPELMDVHVFCTDS

NUDT1

76

P36639
SLHDDGFTVPQIIEM

BIRC6

656

Q9NR09
LKSMDHFDDIGPSVV

CPSF3

311

Q9UKF6
SMEGPDDSEVTFALH

AAMP

76

Q13685
ETFLQMDEVGHIPQT

B4GALNT3

286

Q6L9W6
SMVSFVIGDEHVVLP

ADGB

766

Q8N7X0
SEIVMDFKHPDGIAV

ALKBH8

256

Q96BT7
MVQPDFELHAISGEI

FAT4

1141

Q6V0I7
EMTDELVGLPFSSHT

FBXO34

406

Q9NWN3
GSIEFMTECTTIEHP

AASS

361

Q9UDR5
AISHGVVEVDPMLTL

APLP1

611

P51693
TMVLEAHDAQGDVPV

C3

41

P01024
APATIATPAVFEHME

ACACA

391

Q13085
IDMVSFLLDLGAHPD

ANKEF1

61

Q9NU02
HLSPEEFQEVFGMSI

ABLIM2

576

Q6H8Q1
AMFICSEIPITLDHG

CAPN13

326

Q6MZZ7
PLEALMEVSVSDGIH

CELSR1

1171

Q9NYQ6
EVSHGPSDVESVMLS

CELSR1

1751

Q9NYQ6
MEDGLVNTIPASFHD

NPR1

341

P16066
EMVALSDNIPAGVTH

C7orf31

376

Q8N865
SQIVLHRDGMDPDFT

DIAPH3

466

Q9NSV4
MEDSGLFEAAHVLSP

DMXL1

1306

Q9Y485
VSEEHPEGMVTVAIA

ERMP1

851

Q7Z2K6
GELVLDMEHGTLFSV

ATG2A

956

Q2TAZ0
LADSEVEPSVIGHMS

ARHGEF12

156

Q9NZN5
PGVVDIMTAEHLSDV

AOX1

636

Q06278
TMDIRHFFSGLTIPD

RBM12

16

Q9NTZ6
HFNITEDMLRGIFEP

RBM23

271

Q86U06
FLMEADLGVEVPHEV

RASSF4

256

Q9H2L5
DILAHEAMGDTFPDA

RLN3

56

Q8WXF3
PISDHVLTMKDDGTF

RGS6

96

P49758
GQHFPESSDEMLSLV

CYP1A2

206

P05177
ITVAPVEEMLFHGFS

IQCK

81

Q8N0W5
LFPDSVVGTDSHITM

IREB2

271

P48200
PFMATVLESAEHSEP

PPDPF

66

Q9H3Y8
DEFLGLPSEIHMSEE

NPAT

296

Q14207
TVLHEAVSTGDPEMV

ANKRD13A

76

Q8IZ07
PPHIESFSDVEMGEI

DDX3X

176

O00571
DAPVGSLVMTVSAHD

FAT1

1046

Q14517
LDVHEENIPTVMSAG

NXF3

251

Q9H4D5
IMITHFEPSISFEGL

PRKCI

36

P41743
MAPVEHVVADAGAFL

NOB1

1

Q9ULX3
VSDGEHTSPEMVLTI

FRAS1

1571

Q86XX4
VLSNEPHETMPIAAF

LIN9

271

Q5TKA1
PKIVAFETVHSMDGA

ALAS1

376

P13196
FETVHSMDGAVCPLE

ALAS1

381

P13196
GHSDVVLVDTMDELP

MTMR11

296

A4FU01
VEDSFVHPANEMRIG

LRRC7

626

Q96NW7
DFEETVPTSGRMHID

KCNH7

966

Q9NS40
EEMSGEVRFSSHLPQ

CHUK

246

O15111
TITFPISHSMLDEDG

PHKA1

561

P46020
GAMTVETHEALSFLP

LRRC53

1186

A6NM62
ITMSGDDHPRAFVLD

LRP1

2326

Q07954
HGEAMAEPVASEFVS

KIF26B

1306

Q2KJY2
HEMIPLDSFVGQSAD

HERC1

4646

Q15751
DLFDIMSGQTDVDHP

BECN1

121

Q14457
VLPLAFLGMHEIADE

ECPAS

1481

Q5VYK3
IPESHEIVDLGTMVT

PCLO

2036

Q9Y6V0
SVTMFILLGFTDHPE

OR5A1

11

Q8NGJ0
HGEEVSPAASDLAMV

MTSS2

436

Q765P7
ALEMTGIHAPESSQE

PDZD2

1361

O15018
VASDLHGEDMIVTPF

PDE4C

141

Q08493
HGEDMIVTPFAQVLA

PDE4C

146

Q08493
FGHLEVPSSMFRLDE

LPO

466

P22079
EVHTMEGDPDTLAEF

FAM153A

131

Q9UHL3
LEVIPLVQTFGHMEF

HEXD

81

Q8WVB3
EGLREIHSDIFSPMD

LRP6

256

O75581
VHFPDALEMLSLEGA

LRRK2

571

Q5S007
DGEVTKIMSPHFEEI

METTL9

156

Q9H1A3
AIFLIVFHMDPSDDL

LRRC52

196

Q8N7C0
ADITISLDGVPFLMH

GDPD5

261

Q8WTR4
SMHFLPQVDEIVVLG

ABCC2

821

Q92887
LHSETQRGDVFVPME

LAMA5

1716

O15230
GISDHPQLEMIFFIA

OR2C1

16

O95371
HVAEMEDPSTGAARV

HK3

351

P52790
IPKIVAFETVHSMDG

ALAS2

321

P22557
IVFGTDMKEVDPISH

MAGEA13P

156

A6NCF6
FVRMIAPEGSLVFHE

PITPNB

71

P48739
VEPGEHVTGMELEFK

PTPRS

1671

Q13332
SLDQSVTHLMGLFEP

ALPI

276

P09923
DSPGLVTIAHSMEAV

ORC1

741

Q13415
LEIEGEDFPFVFHSM

OSGIN2

271

Q9Y236
VRVDDEMPQHAVLSG

CADM1

281

Q9BY67
MGVITFLFLIEHPED

SLC37A2

221

Q8TED4
SIAPEDPFVMHEVGV

CDC16

396

Q13042
EDGFSARELMIHAPT

CEP104

16

O60308
PEELQELVDTAHSMG

GBE1

266

Q04446
EFTSDGIPVLMHDNT

GDE1

101

Q9NZC3
PEERMLAAATAFTHI

HYLS1

16

Q96M11
AVEFHPDTGDIIMEF

PRMT7

671

Q9NVM4
PDTGDIIMEFRHADT

PRMT7

676

Q9NVM4
ELSPTPTEELVHMFN

DMAP1

351

Q9NPF5
LPVDHILAGSFETAM

COPA

926

P53621
LSLIECGPVHTAFME

HSD17B1

181

P14061
GFDLVVSPLVHAMSE

EXTL3

311

O43909
EHLAAIVDAVGTMLP

CHAC1

196

Q9BUX1
HFSEPEITLIIFGVM

GYPA

86

P02724
MELPAVGEHVFAVES

CBX4

1

O00257
HEAVGEIMSLSAATP

ACE2

401

Q9BYF1
DAHVEAVMILGEPFA

COQ8B

436

Q96D53
SDPAAIIHDFEKGMT

ITM2A

136

O43736
QVEHPVTEMITGTDL

MCCC1

341

Q96RQ3
HIRATFDPDTGLLME

MAN2B1

611

O00754
TPLMEAAAAGHEIIV

ANKS3

171

Q6ZW76
VMDLGLSEDHFSRPV

DEF8

121

Q6ZN54
QPTVEAGVAHMIEAL

DENND4B

971

O75064
HLGMESFIVVTECEP

CAMKK2

46

Q96RR4
MEQPLDLTHIVGTEV

DYNC1H1

4021

Q14204
DAMFPVTHIAGETVI

PRKAR1B

151

P31321
MVDHLLPVDENFSSP

KLF15

1

Q9UIH9
EQHFPEVMLGEEFLS

KLHL3

176

Q9UH77
ALSHDSIFMLGPEPE

KIAA1210

226

Q9ULL0
ARVHVSEEGTEPEAM

GSN

256

P06396
MPIAHEFSPDVVLVS

HDAC5

946

Q9UQL6
EVDGLPFHNTHAEMI

DGLUCY

591

Q7Z3D6
TMDFPILHLDGIVED

GRIK5

246

Q16478
MEQALHLDFGTELEP

DIPK1A

116

Q5T7M9
MPTTVDDVLEHGGEF

SLC22A2

1

O15244
EIPHEMGDFAVLLSS

SLC39A12

581

Q504Y0
APLFAGTEHRAIMVD

RYR1

2566

P21817
IGVLSSHPFESDTEM

PPFIA2

606

O75334
GLELPVVMETDHIAS

PRDM4

261

Q9UKN5
MALVGSFVPAEEAEI

MSH5

611

O43196
ADLVAITELMHPVGA

GSTT1

166

P30711
MRPVLAAHVFSGEEE

SLC29A3

261

Q9BZD2
GPVQALMEVHEDFFL

TINAGL1

361

Q9GZM7
IHLIVMDPFVDLGIT

SCN4A

571

P35499
GASILPEHDMELAFD

TDRD9

1261

Q8NDG6
SSIPEMILGHLFSQE

NDRG2

191

Q9UN36
EVFHNLDPDGTMSVE

NIN

226

Q8N4C6
VVDIMHGLEPQTIES

EIF5B

726

O60841
DPVGDIVSFMHSFEE

FAF2

131

Q96CS3
MSLVHVGTEAFPISD

ERCC5

476

P28715
VLALEHMFAPVLDGA

PTCH1

1116

Q13635
HMFAPVLDGAVSTLL

PTCH1

1121

Q13635
FREMIPFAVVGSDHE

SEPTIN9

491

Q9UHD8
EEPQEGLEFAHMALA

SH3TC1

1166

Q8TE82
LLGSEEPTEMHLDFI

SECISBP2L

596

Q93073
GPVHAPVFTMSVDVD

STRBP

411

Q96SI9
TLLTHMGVNPLEAEE

NSMCE4A

166

Q9NXX6
FKMVSEPVAHGVAEE

NAP1L3

6

Q99457
IVESFEEAPLHVMVF

SPTLC3

51

Q9NUV7
GTMAEETAPAVLERH

RGN

116

Q15493
LMSFSPAEIPVHEVE

ITGAL

621

P20701
PMSVGTLEEIIDDNH

PSMC1

106

P62191
VHAVIGVLMDDTDPL

PSMC1

156

P62191
HEDLPSGSFIQDDMV

SVEP1

261

Q4LDE5
FSMHDLTTIQGDEPV

REEP3

151

Q6NUK4
PGESMSTDLVHFDIP

ARHGAP44

766

Q17R89
GFLEEVMHDPELLTQ

RASGRF1

981

Q13972
ASVNEVDFEGRTPMH

RIPK4

576

P57078
GAIVSLSDEAPHMLV

OSBPL10

126

Q9BXB5
FVVFTETDLHMPGAP

SLC6A18

386

Q96N87
VLAHTEMPTTLEGAE

SPTBN1

1191

Q01082
EFIDRQPTMVHDGSL

ABCB9

481

Q9NP78
PLMEAASAGHVEVAR

ANKHD1

341

Q8IWZ3
FSFHVPSLEELAGVM

C11orf54

6

Q9H0W9
LTFIRAAETDPGMVH

CNOT2

361

Q9NZN8
IDTESPLMEMFVAHG

SLC7A14

316

Q8TBB6
FIVLTTSAGIMDHEE

RPS15A

101

P62244
PADLQSHLGTEVMVE

TULP4

1296

Q9NRJ4
TLEVRFTPHAEMDLG

TRMO

336

Q9BU70
ILGDVNSIMDPEIHA

RALGAPA1

1071

Q6GYQ0
PMKDETHFEVVESGR

VWF

946

P04275
GLHMATAVLEESDQP

RNASE10

26

Q5GAN6
ELASFLMDHVFIQPG

STAG3

836

Q9UJ98
HPDEEMGFTIDIKSF

PSPC1

56

Q8WXF1
MEEEGHSDLISFQPT

TMEM94

921

Q12767
ETSPHVIQAVMGALE

SF3B1

1221

O75533
VDVLMEAAAHGESDP

POLR2A

1436

P24928
GISHSIMFEELPNVD

PIEZO2

2691

Q9H5I5
FTLDCTHPVEDGIMD

RPL22

21

P35268
PTLFTEMDTLQHDGD

SLC4A5

111

Q9BY07
MNAHLPFAVVGSTEE

SEPTIN8

231

Q92599
FVDNMTLSGPDLELH

STAB1

2376

Q9NY15
LIVSEGKMAPFTHDF

WIF1

56

Q9Y5W5
LVASSPEMGQDFDHV

SPTB

1711

P11277
EAVELHFSSMQGIPL

TTC21A

431

Q8NDW8
RMAEIGEHVAPSEAA

CAD

521

P27708
VAGSTVMVIHAPEEE

NIPAL4

166

Q0D2K0
FSHEVGSELASVPVM

ZC3H7A

226

Q8IWR0
QEASEETELHRMPVG

ZNF621

101

Q6ZSS3
PELHDFMQSAEVGTI

TBC1D20

201

Q96BZ9
IQTEMETVPEAGTHE

ZNF222

51

Q9UK12
LSEELAGHQMPITDI

WDR54

156

Q9H977