Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA1 GRIA3 GRIA4

4.29e-074963GO:0004971
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA1 GRIA3 GRIA4

6.97e-0517963GO:0004970
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2B ASH1L SMYD3

1.16e-0420963GO:0042800
GeneOntologyMolecularFunctiontriplex DNA binding

DDX12P DDX11L8

1.36e-044962GO:0045142
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

HTR3E GRIA1 GRIA3 GRIA4

1.63e-0457964GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

HTR3E GRIA1 GRIA3 GRIA4

1.99e-0460964GO:0099529
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA1 GRIA3 GRIA4

2.03e-0424963GO:0099507
GeneOntologyMolecularFunctiontransmitter-gated channel activity

HTR3E GRIA1 GRIA3 GRIA4

2.71e-0465964GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

HTR3E GRIA1 GRIA3 GRIA4

2.71e-0465964GO:0022824
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA1 GRIA3 GRIA4

2.90e-0427963GO:0008066
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

HTR3E GRIA1 GRIA3 GRIA4

4.70e-0475964GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

HTR3E GRIA1 GRIA3 GRIA4

5.19e-0477964GO:0005230
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIA1 GRIA3

6.29e-048962GO:0022849
GeneOntologyMolecularFunctionbeta-2 adrenergic receptor binding

AKAP5 GRIA1

1.00e-0310962GO:0031698
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2B SMYD3

1.00e-0310962GO:0140999
GeneOntologyMolecularFunction5'-3' DNA helicase activity

DDX12P DDX11L8

1.22e-0311962GO:0043139
GeneOntologyMolecularFunctionDNA endonuclease activity

ZRANB3 N4BP2 MBD4

1.24e-0344963GO:0004520
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2B ASH1L SMYD3

1.24e-0344963GO:0140938
GeneOntologyMolecularFunctionneurotransmitter receptor activity

HTR3E GRIA1 GRIA3 GRIA4

1.38e-03100964GO:0030594
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

DDX12P ZRANB3 LIG3 N4BP2 MBD4 DDX11L8

1.67e-03262966GO:0140097
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

ASH1L SMYD3

1.72e-0313962GO:0046975
GeneOntologyMolecularFunctionG-quadruplex DNA binding

DDX12P DDX11L8

2.00e-0314962GO:0051880
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF1 PRAMEF14 MED25

2.36e-0355963GO:0042974
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

HTR3E TMEM63C GRIA1 GRIA3 GRIA4

2.41e-03193965GO:0015276
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1D CENPE MYO6 DNAH1

2.53e-03118964GO:0003774
GeneOntologyMolecularFunctionadenylate cyclase binding

AKAP5 GRIA1

2.63e-0316962GO:0008179
GeneOntologyMolecularFunctionligand-gated channel activity

HTR3E TMEM63C GRIA1 GRIA3 GRIA4

2.63e-03197965GO:0022834
GeneOntologyMolecularFunctionATP-dependent activity

DDX12P MYO1D CENPE MYO6 ATP10A ZRANB3 NLRP3 DNAH1 DDX11L8

2.79e-03614969GO:0140657
GeneOntologyMolecularFunctionDNA helicase activity

DDX12P ZRANB3 DDX11L8

3.32e-0362963GO:0003678
GeneOntologyMolecularFunctionDNA replication origin binding

DDX12P DDX11L8

3.33e-0318962GO:0003688
GeneOntologyMolecularFunctionSUMO ligase activity

NSMCE2 ZNF451

4.11e-0320962GO:0061665
GeneOntologyMolecularFunctionDNA nuclease activity

ZRANB3 N4BP2 MBD4

4.13e-0367963GO:0004536
GeneOntologyMolecularFunctionphosphatidylinositol binding

SYT9 TWF2 NLRP3 ZFYVE9 MITD1 SNX5

4.22e-03316966GO:0035091
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2B ASH1L SMYD3

4.31e-0368963GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2B ASH1L SMYD3

4.49e-0369963GO:0016278
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

HTR3E TMEM63C GRIA1 GRIA3

4.67e-03140964GO:0099094
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2B ASH1L SMYD3

4.86e-0371963GO:0042054
GeneOntologyBiologicalProcessvesicle cargo loading

CTAGE9 CTAGE6 CTAGE8 CTAGE15 CTAGE4

7.71e-0736995GO:0035459
GeneOntologyBiologicalProcessfemale gamete generation

KMT2B CENPE PRAMEF1 PRAMEF14 ASPM WEE2 CDC25B

1.01e-04223997GO:0007292
GeneOntologyBiologicalProcessoogenesis

KMT2B PRAMEF1 PRAMEF14 ASPM WEE2 CDC25B

1.07e-04156996GO:0048477
GeneOntologyBiologicalProcessoocyte development

KMT2B PRAMEF1 PRAMEF14 WEE2 CDC25B

1.15e-0499995GO:0048599
GeneOntologyBiologicalProcessendoplasmic reticulum to Golgi vesicle-mediated transport

CTAGE9 CTAGE6 SEC22A CTAGE8 CTAGE15 CTAGE4

1.18e-04159996GO:0006888
GeneOntologyBiologicalProcesspositive regulation of transcription elongation by RNA polymerase II

MED9 BRD4 MED11 MED25

1.31e-0454994GO:0032968
GeneOntologyBiologicalProcessoocyte differentiation

KMT2B PRAMEF1 PRAMEF14 WEE2 CDC25B

1.39e-04103995GO:0009994
GeneOntologyBiologicalProcesspositive regulation of T-helper 17 type immune response

NLRP3 CARD9 BRD4

1.77e-0423993GO:2000318
GeneOntologyBiologicalProcesspositive regulation of DNA-templated transcription, elongation

MED9 BRD4 MED11 MED25

2.25e-0462994GO:0032786
GeneOntologyCellularComponentendoplasmic reticulum exit site

CTAGE9 CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.51e-0642985GO:0070971
GeneOntologyCellularComponentpresynaptic active zone membrane

GPM6A GRIA1 GRIA3 GRIA4 RYK

3.29e-0578985GO:0048787
GeneOntologyCellularComponentpresynaptic active zone

GPM6A GRIA1 GRIA3 GRIA4 RYK NR3C2

5.35e-05141986GO:0048786
GeneOntologyCellularComponentneurotransmitter receptor complex

HTR3E GRIA1 GRIA3 GRIA4

8.86e-0550984GO:0098878
GeneOntologyCellularComponentcore mediator complex

MED9 MED11 MED25

2.40e-0426983GO:0070847
GeneOntologyCellularComponentAMPA glutamate receptor complex

GRIA1 GRIA3 GRIA4

3.70e-0430983GO:0032281
GeneOntologyCellularComponentmidbody

DDX12P CENPE LATS1 ASPM DDX11L8 MITD1

6.26e-04222986GO:0030496
GeneOntologyCellularComponentmediator complex

MED9 MED11 MED25

6.92e-0437983GO:0016592
GeneOntologyCellularComponentneuron to neuron synapse

AKAP5 MYO6 SYT9 GRIA1 GRIA3 GRIA4 CNKSR2 RYK NR3C2

7.85e-04523989GO:0098984
GeneOntologyCellularComponentpostsynaptic density membrane

GRIA1 GRIA3 GRIA4 CNKSR2 RYK

8.68e-04157985GO:0098839
GeneOntologyCellularComponentCtf18 RFC-like complex

DDX12P DDX11L8

9.55e-0410982GO:0031390
GeneOntologyCellularComponentcentrosome

DDX12P FBXL13 OFD1 HAP1 HAUS3 LATS1 ASPM CFAP58 CEP152 CDC25B DDX11L8

9.59e-047709811GO:0005813
GeneOntologyCellularComponentdendritic spine

GPM6A AKAP5 HAP1 GRIA1 GRIA3 GRIA4

9.80e-04242986GO:0043197
GeneOntologyCellularComponentneuron spine

GPM6A AKAP5 HAP1 GRIA1 GRIA3 GRIA4

1.09e-03247986GO:0044309
GeneOntologyCellularComponentmicrotubule organizing center

DDX12P FBXL13 OFD1 HAP1 HAUS3 NLRP3 LATS1 ASPM CFAP58 CEP152 CDC25B DDX11L8

1.22e-039199812GO:0005815
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA1 GRIA3 GRIA4

1.23e-0345983GO:0008328
GeneOntologyCellularComponentpostsynaptic density

AKAP5 MYO6 GRIA1 GRIA3 GRIA4 CNKSR2 RYK NR3C2

1.28e-03451988GO:0014069
GeneOntologyCellularComponentglutamatergic synapse

PRUNE2 GPM6A AKAP5 MYO6 GRIA1 GRIA3 GRIA4 CNKSR2 PDE10A RYK NR3C2

1.54e-038179811GO:0098978
GeneOntologyCellularComponentpostsynaptic density, intracellular component

AKAP5 GRIA1 NR3C2

1.57e-0349983GO:0099092
GeneOntologyCellularComponentexcitatory synapse

GPM6A AKAP5 GRIA1 GRIA3

1.62e-03107984GO:0060076
GeneOntologyCellularComponentasymmetric synapse

AKAP5 MYO6 GRIA1 GRIA3 GRIA4 CNKSR2 RYK NR3C2

1.82e-03477988GO:0032279
GeneOntologyCellularComponentnuclear protein-containing complex

DDX12P MIS18BP1 KMT2B MED9 IVNS1ABP LIG3 SNRNP48 PBRM1 R3HCC1L BRD4 MED11 MED25 FIP1L1 AFF1 DDX11L8

1.83e-0313779815GO:0140513
GeneOntologyCellularComponentactin-based cell projection

GPM6A AKAP5 MYO1D MYO6 CDHR2 TWF2

1.99e-03278986GO:0098858
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

AKAP5 GRIA1 NR3C2

2.31e-0356983GO:0099091
GeneOntologyCellularComponentpostsynaptic specialization

AKAP5 MYO6 GRIA1 GRIA3 GRIA4 CNKSR2 RYK NR3C2

2.52e-03503988GO:0099572
GeneOntologyCellularComponentpostsynaptic specialization membrane

GRIA1 GRIA3 GRIA4 CNKSR2 RYK

2.58e-03201985GO:0099634
GeneOntologyCellularComponentfilopodium

GPM6A AKAP5 MYO6 TWF2

2.69e-03123984GO:0030175
GeneOntologyCellularComponentspindle pole

DDX12P LATS1 ASPM CDC25B DDX11L8

2.81e-03205985GO:0000922
GeneOntologyCellularComponentpresynapse

PRUNE2 GPM6A MYO6 HAP1 ATCAY SYT9 GRIA1 GRIA3 GRIA4 RYK NR3C2

2.90e-038869811GO:0098793
GeneOntologyCellularComponentdendritic spine membrane

AKAP5 GRIA1

3.17e-0318982GO:0032591
GeneOntologyCellularComponentcluster of actin-based cell projections

MYO1D MYO6 CDHR2 TWF2 SNX5

4.02e-03223985GO:0098862
GeneOntologyCellularComponentdendritic shaft

AKAP5 GRIA1 GRIA3

5.09e-0374983GO:0043198
DomainASH

ASPM HYDIN

2.30e-052902IPR031549
DomainASH

ASPM HYDIN

2.30e-052902PF15780
DomainIontro_rcpt

GRIA1 GRIA3 GRIA4

8.38e-0518903IPR001320
DomainLig_chan-Glu_bd

GRIA1 GRIA3 GRIA4

8.38e-0518903PF10613
DomainIono_rcpt_met

GRIA1 GRIA3 GRIA4

8.38e-0518903IPR001508
DomainGlu/Gly-bd

GRIA1 GRIA3 GRIA4

8.38e-0518903IPR019594
DomainLig_chan-Glu_bd

GRIA1 GRIA3 GRIA4

8.38e-0518903SM00918
DomainLig_chan

GRIA1 GRIA3 GRIA4

8.38e-0518903PF00060
DomainPBPe

GRIA1 GRIA3 GRIA4

8.38e-0518903SM00079
DomainBNIP2

PRUNE2 ATCAY

1.37e-044902PF12496
DomainBcl2-/adenovirus-E1B

PRUNE2 ATCAY

1.37e-044902IPR022181
DomainIQ

MYO1D MYO6 SCN9A ASPM

3.83e-0471904PF00612
DomainIQ

MYO1D MYO6 SCN9A ASPM

6.32e-0481904SM00015
DomainANF_lig-bd_rcpt

GRIA1 GRIA3 GRIA4

7.47e-0437903IPR001828
DomainBROMODOMAIN_1

ASH1L PBRM1 BRD4

7.47e-0437903PS00633
DomainANF_receptor

GRIA1 GRIA3 GRIA4

7.47e-0437903PF01094
DomainP-loop_NTPase

GTPBP4 MYO1D CENPE MYO6 ZRANB3 NLRP3 DNAH1 SAMD9L N4BP2 ASPM HYDIN ARL14

7.48e-048489012IPR027417
DomainBromodomain

ASH1L PBRM1 BRD4

8.08e-0438903PF00439
DomainPeripla_BP_I

GRIA1 GRIA3 GRIA4

8.72e-0439903IPR028082
DomainIQ_motif_EF-hand-BS

MYO1D MYO6 SCN9A ASPM

9.39e-0490904IPR000048
DomainSET

KMT2B ASH1L SMYD3

1.01e-0341903PF00856
DomainBROMODOMAIN_2

ASH1L PBRM1 BRD4

1.01e-0341903PS50014
DomainIQ

MYO1D MYO6 SCN9A ASPM

1.06e-0393904PS50096
DomainBROMO

ASH1L PBRM1 BRD4

1.08e-0342903SM00297
DomainBromodomain

ASH1L PBRM1 BRD4

1.08e-0342903IPR001487
Domain-

ASH1L PBRM1 BRD4

1.08e-03429031.20.920.10
DomainBAH

ASH1L PBRM1

1.23e-0311902SM00439
DomainBAH

ASH1L PBRM1

1.23e-0311902PF01426
DomainBAH

ASH1L PBRM1

1.23e-0311902PS51038
DomainBAH_dom

ASH1L PBRM1

1.23e-0311902IPR001025
DomainSET

KMT2B ASH1L SMYD3

1.41e-0346903SM00317
DomainCRAL_TRIO_2

PRUNE2 ATCAY

1.47e-0312902PF13716
DomainSET_dom

KMT2B ASH1L SMYD3

1.80e-0350903IPR001214
DomainSET

KMT2B ASH1L SMYD3

1.80e-0350903PS50280
DomainPost-SET_dom

KMT2B ASH1L

2.64e-0316902IPR003616
DomainPostSET

KMT2B ASH1L

2.64e-0316902SM00508
DomainPOST_SET

KMT2B ASH1L

2.64e-0316902PS50868
DomainCRAL_TRIO

PRUNE2 ATCAY

4.54e-0321902PF00650
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

AKAP5 MYO6 GRIA1 GRIA3 GRIA4

2.44e-0729685MM15028
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

AKAP5 MYO6 GRIA1 GRIA3 GRIA4

3.47e-0731685M7223
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA1 GRIA3 GRIA4

5.75e-0516683MM15048
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

GRIA1 GRIA3 GRIA4

6.96e-0517683M5488
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA1 GRIA3 GRIA4

8.32e-0518683M48098
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA1 GRIA3 GRIA4

1.15e-0420683MM15485
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA1 GRIA3 GRIA4

1.34e-0421683M27736
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA1 GRIA3 GRIA4

1.34e-0421683M838
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

GRIA1 GRIA3 GRIA4

1.55e-0422683M39795
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA1 GRIA3 GRIA4

1.55e-0422683MM15104
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

AKAP5 MYO6 HTR3E GRIA1 GRIA3 GRIA4

4.55e-04205686M752
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

GRIA1 GRIA3 GRIA4

6.29e-0435683MM15109
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

AKAP5 MYO6 GRIA1 GRIA3 GRIA4

6.45e-04144685MM14501
PathwayREACTOME_CARGO_CONCENTRATION_IN_THE_ER

CTAGE9 GRIA1 CTAGE8

6.84e-0436683MM15300
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

SYT9 GRIA1 GRIA3 GRIA4

8.16e-0487684M27617
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

GRIA1 GRIA3 GRIA4

1.00e-0341683M39655
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

AKAP5 MYO1D ZNF658 U2SURP ASH1L GRIA1 FAM47B GRIA3 GRIA4 CTAGE6 PDE10A MIPOL1 SNRNP48 LATS1 N4BP2 CTAGE8 MED11 SCN9A ASPM CTAGE15 CTAGE4

8.74e-1014421012135575683
Pubmed

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

AKAP5 MYO6 GRIA1 GRIA3 GRIA4

1.55e-0918101518311135
Pubmed

Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.

GRIA1 GRIA3 GRIA4

2.38e-083101312172541
Pubmed

Synaptic AMPA receptor plasticity and behavior.

GRIA1 GRIA3 GRIA4

2.38e-083101319217372
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA1 GRIA3 GRIA4

9.49e-084101310688364
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA1 GRIA3 GRIA4

9.49e-08410139221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA1 GRIA3 GRIA4

9.49e-084101325337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA1 GRIA3 GRIA4

9.49e-084101317828255
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA1 GRIA3 GRIA4

9.49e-084101324652293
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA1 GRIA3 GRIA4

9.49e-084101317409242
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA1 GRIA3 GRIA4

9.49e-084101314561864
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA1 GRIA3 GRIA4

9.49e-08410131319477
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA1 GRIA3 GRIA4

9.49e-084101312692557
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA1 GRIA3 GRIA4

9.49e-084101312125045
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA1 GRIA3 GRIA4

9.49e-08410139648857
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA1 GRIA3 GRIA4

2.37e-075101316129400
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA1 GRIA3 GRIA4

2.37e-07510139482932
Pubmed

Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.

GRIA1 GRIA3 GRIA4

8.25e-077101321368048
Pubmed

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.

GRIA1 GRIA3 GRIA4

8.25e-077101333981040
Pubmed

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

GRIA1 GRIA3 GRIA4

8.25e-077101310407040
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA1 GRIA3 GRIA4

8.25e-07710139016303
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA1 GRIA3 GRIA4

8.25e-07710139651535
Pubmed

TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.

GRIA1 GRIA3 GRIA4

8.25e-077101327076426
Pubmed

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.

GRIA1 GRIA3 GRIA4

1.32e-068101321172611
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA1 GRIA3 GRIA4

1.32e-068101323217150
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 TIGAR UACA MYO6 ASH1L TMEM63C STK32C PDE10A NSMCE2 SEC22A ATP10A DNAH1 MIPOL1 ANKRD11 AFF1 SMYD3 SOS2

1.32e-0614891011728611215
Pubmed

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

GRIA1 GRIA3 GRIA4

1.97e-069101324292102
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA1 GRIA3 GRIA4

1.97e-06910139051806
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRIA1 GRIA3 GRIA4

5.13e-0612101311891216
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

GRIA1 GRIA4 PDE10A SEC22A CC2D2B IVNS1ABP SAMD9L ZNF451 SCN9A HYDIN ARL14

5.17e-066861011129987050
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIA1 GRIA3 GRIA4

6.66e-0613101320859245
Pubmed

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.

GRIA1 GRIA3 GRIA4

6.66e-0613101325218043
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

OFD1 STK32C NSMCE2 IVNS1ABP LATS1 N4BP2 BRD4 ANKRD11 FIP1L1 NR3C2 CEP152 CDC25B

7.79e-068611011236931259
Pubmed

Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3.

GRIA1 GRIA3

8.35e-062101227708157
Pubmed

Synaptic plasticity through activation of GluA3-containing AMPA-receptors.

GRIA1 GRIA3

8.35e-062101228762944
Pubmed

Kinetic properties of human AMPA-type glutamate receptors expressed in HEK293 cells.

GRIA3 GRIA4

8.35e-062101212670305
Pubmed

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing.

GRIA3 GRIA4

8.35e-06210127992055
Pubmed

Common variants in the regulative regions of GRIA1 and GRIA3 receptor genes are associated with migraine susceptibility.

GRIA1 GRIA3

8.35e-062101220579352
Pubmed

Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms.

AKAP5 GRIA1

8.35e-062101222623657
Pubmed

Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3.

GRIA1 GRIA3

8.35e-062101228103481
Pubmed

Elimination of redundant synaptic inputs in the absence of synaptic strengthening.

GRIA3 GRIA4

8.35e-062101222090494
Pubmed

AKAP79 selectively enhances protein kinase C regulation of GluR1 at a Ca2+-calmodulin-dependent protein kinase II/protein kinase C site.

AKAP5 GRIA1

8.35e-062101218305116
Pubmed

Preferential generation of Ca2+-permeable AMPA receptors by AKAP79-anchored protein kinase C proceeds via GluA1 subunit phosphorylation at Ser-831.

AKAP5 GRIA1

8.35e-062101230737285
Pubmed

NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus.

NLRP3 NR3C2

8.35e-062101231817997
Pubmed

Distinct effects of AMPAR subunit depletion on spatial memory.

GRIA1 GRIA3

8.35e-062101237876813
Pubmed

E-cigarette exposure with or without heating the e-liquid induces differential remodeling in the lungs and right heart of mice.

NLRP3 CARD9

8.35e-062101235489388
Pubmed

Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4.

GRIA3 GRIA4

8.35e-062101218316356
Pubmed

A pathway-specific function for different AMPA receptor subunits in amygdala long-term potentiation and fear conditioning.

GRIA1 GRIA3

8.35e-062101217928436
Pubmed

Characterization of the functional role of the N-glycans in the AMPA receptor ligand-binding domain.

GRIA1 GRIA4

8.35e-062101212603841
Pubmed

NR3C2 mediates oxidised low-density lipoprotein-induced human coronary endothelial cells dysfunction via modulation of NLRP3 inflammasome activation.

NLRP3 NR3C2

8.35e-062101236919662
Pubmed

BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis.

NLRP3 BRD4

8.35e-062101235154163
Pubmed

GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse.

GRIA3 GRIA4

8.35e-062101221690196
Pubmed

Ca2+/calmodulin-dependent protein kinase II inhibitors disrupt AKAP79-dependent PKC signaling to GluA1 AMPA receptors.

AKAP5 GRIA1

8.35e-062101221156788
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

GRIA1 GRIA3 GRIA4

1.05e-051510139481670
Pubmed

PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.

GRIA1 GRIA3 GRIA4

1.30e-0516101316055064
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

MIS18BP1 OFD1 MED9 HAUS3 LIG3 PBRM1 MED11 MED25 FIP1L1 CEP152

1.90e-056451011025281560
Pubmed

NMDAR-dependent presynaptic homeostasis in adult hippocampus: Synapse growth and cross-modal inhibitory plasticity.

GRIA1 GRIA3

2.50e-053101236070750
Pubmed

Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior.

GRIA1 GRIA4

2.50e-053101217296559
Pubmed

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia.

GRIA1 GRIA4

2.50e-053101222094384
Pubmed

The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells.

GRIA3 GRIA4

2.50e-053101228397107
Pubmed

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain.

GRIA1 GRIA3

2.50e-053101232569783
Pubmed

Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex.

GRIA1 GRIA3

2.50e-053101236223737
Pubmed

Persistent synaptic scaling independent of AMPA receptor subunit composition.

GRIA1 GRIA3

2.50e-053101223864664
Pubmed

AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.

GRIA1 GRIA3

2.50e-053101234426577
Pubmed

Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder.

GRIA1 GRIA4

2.50e-053101222057216
Pubmed

Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage.

GRIA1 GRIA3

2.50e-053101215144856
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA3 GRIA4

2.50e-053101218163426
Pubmed

Glutamate receptor subunit 3 is modified by site-specific limited proteolysis including cleavage by gamma-secretase.

GRIA1 GRIA3

2.50e-053101212700243
Pubmed

Ca2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) activity.

AKAP5 GRIA1

2.50e-053101219858198
Pubmed

Proteomic analysis of the enterocyte brush border.

MYO1D CDHR2

2.50e-053101221330445
Pubmed

Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

DDX12P DDX11L8

2.50e-053101217611414
Pubmed

The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling.

MYO6 RYK

2.50e-053101222773843
Pubmed

AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy.

GRIA1 GRIA3

2.50e-053101215145077
Pubmed

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain.

GRIA1 GRIA3

2.50e-053101228290985
Pubmed

Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain.

GRIA1 GRIA3

2.50e-053101226585043
Pubmed

Glutamatergic plasticity by synaptic delivery of GluR-B(long)-containing AMPA receptors.

GRIA1 GRIA3

2.50e-053101214687553
Pubmed

Synaptic homeostasis requires the membrane-proximal carboxy tail of GluA2.

GRIA1 GRIA3

2.50e-053101229180434
Pubmed

Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder.

GRIA1 GRIA4

2.50e-053101222122651
Pubmed

Mammalian ChlR1 has a role in heterochromatin organization.

DDX12P DDX11L8

2.50e-053101221854770
Pubmed

Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approach.

GRIA1 GRIA3

2.50e-053101219409270
Pubmed

Synaptic targeting of AMPA receptors is regulated by a CaMKII site in the first intracellular loop of GluA1.

GRIA1 GRIA3

2.50e-053101221135237
Pubmed

Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting.

GRIA1 GRIA3

2.50e-053101228630296
Pubmed

LTP requires a reserve pool of glutamate receptors independent of subunit type.

GRIA1 GRIA3

2.50e-053101223235828
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

TLK2 UACA CENPE U2SURP DNAJB4 HAUS3 PROSER1 NSMCE2 PBRM1 ZNF451 ASPM CEP152 CDC25B

3.05e-0511551011320360068
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

GTPBP4 MIS18BP1 DNAJB4 LIG3 PBRM1 ZNF451 BRD4 MED11 MED25 FIP1L1 SMS MBD4

3.89e-0510141011232416067
Pubmed

Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.

GRIA1 GRIA3 GRIA4

4.04e-052310138464923
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIA1 GRIA3 GRIA4

4.60e-0524101335746896
Pubmed

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.

GRIA1 GRIA3 GRIA4

4.60e-0524101322632720
Pubmed

Wee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumption.

WEE2 CDC25B

4.99e-054101220083600
Pubmed

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.

GRIA3 GRIA4

4.99e-054101228608780
Pubmed

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons.

GRIA1 GRIA3

4.99e-054101226932439
Pubmed

Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.

GRIA1 GRIA3

4.99e-054101231231192
Pubmed

A Minor Subset of Super Elongation Complexes Plays a Predominant Role in Reversing HIV-1 Latency.

BRD4 AFF1

4.99e-054101226830226
Pubmed

Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.

CTAGE9 CTAGE8

4.99e-054101227311593
Pubmed

MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.

CTAGE9 CTAGE8

4.99e-054101231244610
Pubmed

AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity.

GRIA1 GRIA3

4.99e-054101231992779
Pubmed

Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients.

GRIA1 GRIA3

4.99e-054101219295509
Pubmed

LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory.

GRIA1 GRIA4

4.99e-054101229915039
Pubmed

Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.

CTAGE9 CTAGE8

4.99e-054101221807889
Pubmed

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.

GRIA1 GRIA3

4.99e-054101232831170
InteractionCTAGE1 interactions

CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.08e-0710984int:CTAGE1
Cytoband7q35

CTAGE6 CTAGE8 CTAGE15 CTAGE4

6.90e-065510147q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

CTAGE6 CTAGE8 CTAGE15 CTAGE4

1.43e-05661014chr7q35
GeneFamilyCTAGE family

CTAGE9 CTAGE6 CTAGE8 CTAGE15 CTAGE4

2.72e-0915735907
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA1 GRIA3 GRIA4

2.52e-0747331200
GeneFamilyCyclins|Mediator complex

MED9 MED11 MED25

3.16e-04337331061
GeneFamilyRho GTPase activating proteins|BCH domain containing

PRUNE2 ATCAY

3.33e-0477321299
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2B ASH1L SMYD3

3.45e-0434733487
GeneFamilyPRAME family

PRAMEF1 PRAMEF14

4.19e-0324732686
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

TLK2 MIS18BP1 UACA CENPE MYO6 HAUS3 PROSER1 SNRNP48 ZFYVE9 ASPM ANKRD11

1.08e-054699811Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

TLK2 ASH1L GRIA3 PBRM1 ZNF451 ASPM ANKRD11 FIP1L1

2.69e-05259988gudmap_developingGonad_e12.5_epididymis_k3_1000
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 MIS18BP1 CENPE ATCAY ATP10A ASPM CDC25B

2.12e-07184101716aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellPND01-03-samps-Myeloid-Macrophage-macrophage-B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MRC1 MIS18BP1 ATP10A TBC1D9 MED11 ASPM

1.31e-0615210165ce8920aedd39a4daf7082153b5e213707c14227
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 AKAP5 ATP10A TBC1D9 IVNS1ABP

3.72e-0618210163dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 CENPE CC2D2B ASPM ARHGAP29 CDC25B

3.84e-06183101652af3c943116073c8ddd207b664342960b88929b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 AKAP5 ATP10A TBC1D9 IVNS1ABP

4.08e-061851016afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 MIS18BP1 CENPE ATCAY ATP10A CDC25B

4.08e-061851016b4af9ae4c358b48357cb135b740266e1652d886a
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SAMD9L SCN9A ARHGAP29 CDC25B

4.34e-061871016f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SCN9A ARHGAP29 NR3C2 CDC25B

4.76e-061901016474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 CENPE ZBTB8B STK32C ASPM CDC25B

4.91e-061911016239300ff76f2c855b2b04d3002461158be90a01b
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MRC1 AKAP5 MIS18BP1 SAMD9L ASPM CEP152

5.52e-061951016c96755d2eb98112b703b5dbee9c88730ace7dcbf
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

UACA CENPE MYO6 ASPM CEP152 CDC25B

5.86e-0619710160fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

UACA MYO6 SAMD9L SCN9A ARHGAP29 RBM43

6.39e-06200101689821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH1 TTC29 CFAP58 WDR49 HYDIN

2.76e-0515510155f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH1 TTC29 CFAP58 WDR49 HYDIN

2.76e-0515510150944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FBXL13 CEP152 CCDC171 WDR49 HYDIN

2.93e-051571015410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 CENPE HAUS3 ASPM CDC25B

3.62e-051641015ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP5 MIS18BP1 CENPE ZRANB3 ASPM

3.72e-05165101596f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 MRC1 MIS18BP1 CENPE HAUS3

3.83e-051661015bb8135119dc37fdbba476599a56d368f422688dc
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 MRC1 MIS18BP1 CENPE CEP152

4.17e-051691015a1efc20e34a81ae32f8d278a5486811ade03ef24
ToppCellTCGA-Brain|World / Sample_Type by Project: Shred V9

GPM6A ATCAY GRIA1 GRIA3 GRIA4

4.29e-051701015f78e360a6a44d599ec0d207cba4704e50aa314f8
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 CENPE ATP10A MED25 ASPM

4.79e-05174101572df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MIS18BP1 CENPE ATP10A MED25 ASPM

4.79e-051741015c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASH1L SAMD9L ANKRD11 ARHGAP29 NR3C2

5.34e-05178101501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SCN9A ARHGAP29 CDC25B

5.63e-051801015544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 CENPE TBC1D9 ASPM

5.63e-05180101543fd5c498a87bb078d101298b472656f3294686a
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SCN9A ARHGAP29 CDC25B

5.63e-05180101530cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 CENPE GRIA1 GRIA4 ASPM

5.93e-051821015904804813849b7f7f716ba1554d33b07bc0a701e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 CENPE GRIA1 GRIA4 ASPM

5.93e-0518210155d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 TBC1D9 IVNS1ABP ASPM

6.09e-05183101542dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 MRC1 CENPE TBC1D9 ASPM

6.09e-051831015e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 CNKSR2 DNAH1 SCN9A HYDIN

6.25e-0518410152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 CNKSR2 DNAH1 SCN9A HYDIN

6.25e-051841015ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 CNKSR2 DNAH1 SCN9A HYDIN

6.25e-0518410152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 MRC1 CENPE TBC1D9 ASPM

6.41e-05185101557c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 AKAP5 ATP10A TBC1D9

6.41e-051851015775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

FBXL13 TTC29 CFAP58 WDR49 HYDIN

6.41e-05185101530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SCN9A ARHGAP29 CDC25B

6.91e-05188101573f6ec915934154f435a376cb274b058ff7c5f35
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 ATP10A TBC1D9 IVNS1ABP

7.09e-051891015287e59104687fe1665232c52993889f0f2c97f17
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MIS18BP1 CENPE ATCAY ASPM CDC25B

7.09e-051891015815afad947ed77a8b03724bf78014799fed34f54
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 MRC1 ATP10A TBC1D9 IVNS1ABP

7.09e-0518910156d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 CENPE PBRM1 ASPM CDC25B

7.27e-0519010154288189e3a499c395896c950598810b02f401685
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

MRC1 MIS18BP1 CENPE SCN9A ASPM

7.64e-051921015a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MIS18BP1 CENPE ASPM CEP152 CDC25B

7.64e-05192101527723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MIS18BP1 CENPE ASPM CEP152 CDC25B

7.64e-0519210150a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SCN9A ARHGAP29 CDC25B

7.64e-051921015c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPM6A MRC1 DNAJB4 SCN9A ARHGAP29

7.64e-051921015cbe57cda44232b183821ac633b60a2668265e616
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

CENPE ASH1L BRD4 ASPM ANKRD11

7.64e-0519210159cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MIS18BP1 CENPE ZRANB3 ASPM CEP152

7.82e-0519310154b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA MYO6 SCN9A ARHGAP29 CDC25B

7.82e-051931015a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MIS18BP1 ASPM CEP152 CCDC171 WDR49

8.02e-051941015dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 MIS18BP1 CENPE TBC1D9 ASPM

8.21e-051951015c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

8.41e-0519610155905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MRC1 UACA MYO6 PDE10A ARHGAP29

8.62e-0519710154e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCellmyeloid-pro-pDC|World / Lineage and Cell class

CENPE GRIA3 N4BP2 SCN9A ASPM

8.62e-0519710158918ee006b16f6b86ed33ce1dd5c0f01f51f88f5
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 UACA CENPE ASPM CDC25B

8.83e-0519810155f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 UACA CENPE ASPM CDC25B

8.83e-051981015629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

8.83e-051981015dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCell15-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.04e-0519910155c8b847b794b3e88722f5b841f2539a27251106c
ToppCellNon-neuronal-Dividing-IPC-IPC-div1-28|World / Primary Cells by Cluster

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.04e-051991015787688b68ae5d8768c0a24673ae07ab07616764a
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.04e-051991015a99516a5760f49a69b0fe45a9b2316e393252966
ToppCellNon-neuronal-Dividing-IPC-IPC-div1|World / Primary Cells by Cluster

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.04e-05199101572823f26ecabcae1b514b7629cfce010c97b929a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 UACA CENPE ASPM CDC25B

9.04e-051991015ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_ventral_progenitors|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.04e-051991015446cd7d960812519fe2b8e434578ef0b668c75ce
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.04e-051991015d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010158f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010152938a029fa0478be561574ace91f95c4a528b2d4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010150d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

UACA MYO6 SAMD9L SCN9A ARHGAP29

9.25e-052001015bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

UACA MYO6 SAMD9L SCN9A ARHGAP29

9.25e-052001015edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010150675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_ventral_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010159359faa749f41aaef70b4874f20b4eed2dc12cc2
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells|3m / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

UACA MYO6 SAMD9L SCN9A ARHGAP29

9.25e-05200101579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015203b9a5de4430713da01b3331e69381db449a3a0
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

MIS18BP1 CENPE IVNS1ABP ASPM CEP152

9.25e-0520010154923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015a854e19703dc920e48304541e2b06ed013292f3e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CDC25B SNX5

9.25e-052001015b71138729d2a81cc2f30e3bc15853516a525a17f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Stem_cells|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015008f137920cc3b599376706803c111d1d0ec17ef
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-052001015971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

MIS18BP1 CENPE IVNS1ABP ASPM CEP152

9.25e-052001015dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

UACA MYO6 SAMD9L SCN9A ARHGAP29

9.25e-052001015be55cef682ba87250dad97689332c8820b3a7420
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Stem_cells-Stem_cells|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CDC25B SNX5

9.25e-0520010158f3067b52865a0f5488e4df0d5a4fea80135cef5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Stem_cells-Neuroepithelial_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010150e119c2742f2be19fde8890d1227bf277ead976f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MIS18BP1 CENPE ASPM CEP152 CDC25B

9.25e-0520010158f9e76048ae6f45218a09a95a2c4b31e8a8937b2
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MIS18BP1 ASH1L TBC1D9 ANKRD11

2.53e-041351014b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GPM6A PDE10A ZRANB3 ZIK1

2.67e-0413710149bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

MIS18BP1 ASH1L BRD4 ANKRD11

2.75e-041381014817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

EVPL SAMD9L ZFYVE9 CFAP58

2.90e-041401014407691970ec72a3afb45e431cf48814546b8acff
ToppCellCOVID-19_Mild-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

CTAGE9 CTAGE6 TTC29 ARHGAP29

2.90e-041401014b1429028c52f84127b894b93b55961badcd5246f
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTAGE9 CTAGE6 TTC29 ARHGAP29

3.15e-0414310149836a040a2ebcf6f05431e658a7b8fd566621452
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CTAGE9 CTAGE6 TTC29 ARHGAP29

3.15e-0414310144622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCellHealthy-CD4+_T_activated|Healthy / disease group, cell group and cell class

EVPL SAMD9L ZFYVE9 CFAP58

3.32e-04145101445e8089fdf7d6f69b383816d8945e39fba24c873
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTC29 CFAP58 WDR49 HYDIN

3.58e-041481014d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTC29 CFAP58 WDR49 HYDIN

3.58e-041481014c8e93b87212f55774223caa385859c566fa1981f
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH1 TTC29 CFAP58 HYDIN

4.16e-0415410149ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH1 TTC29 CFAP58 HYDIN

4.16e-04154101458072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 ASPM CEP152 MBD4

4.48e-0415710140fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

N4BP2 ZNF451 WEE2 HYDIN

4.48e-041571014370f44047ef438b8f1124c2c2761c150c0d8c57f
Drugisothiazol-3-one

GRIA1 GRIA3 GRIA4 MITD1

3.84e-089974CID000096917
Drug3-pyridazinol 1-oxide

GRIA1 GRIA3 GRIA4

2.99e-074973CID000574311
DrugAC1L1YEG

GRIA1 GRIA3 GRIA4

7.45e-075973CID000063114
DrugChicago acid

GRIA1 GRIA3 GRIA4

7.45e-075973CID000065740
DrugCHEBI:570577

GRIA1 GRIA3 GRIA4

7.45e-075973CID011334126
Drug1-BCP

GRIA1 GRIA3 GRIA4

7.45e-075973CID000001370
Drugirampanel

GRIA1 GRIA3 GRIA4

7.45e-075973CID003038472
Drugbeta-N-oxalylaminoalanine

GRIA1 GRIA3 GRIA4

7.45e-075973CID000107978
DrugLY395153

GRIA1 GRIA3 GRIA4

7.45e-075973CID000656707
Drug5-h PCA

GRIA1 GRIA3 GRIA4

7.45e-075973CID000129091
Drug2cmo

GRIA1 GRIA3 GRIA4

1.49e-066973CID006914597
DrugYM928

GRIA1 GRIA3 GRIA4

1.49e-066973CID006918393
DrugM100907

HTR3E GRIA1 GRIA3 GRIA4 LATS1

2.54e-0651975CID000060858
Drugthio-ATPA

GRIA1 GRIA3 GRIA4

2.59e-067973CID005289517
Drug4,6-dichloroindole-2-carboxylic acid

GRIA1 GRIA3 GRIA4

2.59e-067973CID000127988
Drug2,3-PDCA

GRIA1 GRIA3 GRIA4

4.13e-068973CID000127037
Drughomoibotenic acid

GRIA1 GRIA3 GRIA4

4.13e-068973CID000194385
Drug1-hydroxypyrazole

GRIA1 GRIA3 GRIA4

4.13e-068973CID003016733
Drug1-hydroxyimidazole

GRIA1 GRIA3 GRIA4

4.13e-068973CID003614351
DrugLy294486

GRIA1 GRIA3 GRIA4

6.18e-069973CID005311255
Drug1m5b

GRIA1 GRIA3 GRIA4

6.18e-069973CID000447081
DrugBenzoates

GRIA1 GRIA3 GRIA4

8.80e-0610973ctd:D001565
Drug0-ol

GRIA1 GRIA3 GRIA4

1.21e-0511973CID000069892
DrugJ-ST

GRIA1 GRIA3 GRIA4

1.21e-0511973CID005288655
Drugsym 2206

GRIA1 GRIA3 GRIA4

1.21e-0511973CID005039877
DrugYM872

GRIA1 GRIA3 GRIA4

1.21e-0511973CID000148200
Drug5-Acetamido-5,6-Dihydro-4-Hydroxy-6-Isobutoxy-4h-Pyran-2-Carboxylic Acid

GRIA1 GRIA3 EVPL GRIA4 SCN9A

1.51e-0573975CID011963505
DrugC-X6

GRIA1 GRIA3 GRIA4

1.60e-0512973CID005288002
DrugAtpa

GRIA1 GRIA3 GRIA4

1.60e-0512973CID000002252
Drug1NaPP1

GRIA1 GRIA3 GRIA4

1.60e-0512973CID000004877
Drug5-fluorowillardiine

GRIA1 GRIA3

1.80e-052972ctd:C095178
DrugKSCN

GRIA1 GRIA4 NR3C2 MITD1

1.84e-0537974CID000516872
DrugNaspm

GRIA1 GRIA3 GRIA4

2.08e-0513973CID000129695
DrugRibostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A

MED9 U2SURP DNAJB4 EVPL TWF2 BRD4 CEP152

2.17e-051979773444_DN
DrugVidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A

GTPBP4 KMT2B MED9 DNAJB4 TWF2 CEP152 SOS2

2.32e-051999773445_DN
Drugquinoxaline-2,3-dione

GRIA1 GRIA3 GRIA4

2.64e-0514973CID011469229
Drugthiokynurenic acid

GRIA1 GRIA3 GRIA4

3.29e-0515973CID003035667
DrugJoro spider toxin

GRIA1 GRIA3 GRIA4 LATS1

3.36e-0543974CID000119582
DrugLY233536

GRIA1 GRIA3 GRIA4

4.03e-0516973CID000126239
Drugdecahydroisoquinoline

GRIA1 GRIA3 GRIA4

4.03e-0516973CID000097812
Drug7-Cl-Thio-Kyna

GRIA1 GRIA3 GRIA4

4.88e-0517973CID003035668
DrugPPNDS

GRIA1 GRIA3 GRIA4

4.88e-0517973CID005961627
Drugmethylenecyclopropylglycine

GRIA1 GRIA3 GRIA4 MBD4

5.66e-0549974CID000441452
DrugMNQX

GRIA1 GRIA3 GRIA4

5.84e-0518973CID000130818
DrugLY382884

GRIA1 GRIA3 GRIA4

6.91e-0519973CID000656723
Druglacosamide

GRIA1 GRIA3 GRIA4 SCN9A

7.16e-0552974CID000219078
DrugIDRA 21

GRIA1 GRIA3 GRIA4

8.11e-0520973CID000003688
DrugAC1L1B62

GRIA1 GRIA3 GRIA4

9.43e-0521973CID000001299
Drug3-isoxazolol

GRIA1 GRIA4

1.07e-044972CID009964065
Drugsunifiram

GRIA1 GRIA4

1.07e-044972CID004223812
Drug4-(chloromethyl)-3-methoxy-5-methylisoxazole

GRIA1 GRIA4

1.07e-044972CID011105661
DrugNS 102

GRIA1 GRIA3 GRIA4

1.09e-0422973CID005282252
DrugFe-mo-s Cluster

GRIA1 GRIA3 GRIA4

1.09e-0422973CID000445682
DrugCX516

GRIA1 GRIA3 GRIA4

1.09e-0422973CID000148184
Drugtroglitazone; Up 200; 10uM; PC3; HT_HG-U133A

GTPBP4 PDE10A ATP10A ZFYVE9 SCN9A ARL14

1.19e-041799764456_UP
DrugCGP 39653

GRIA1 GRIA3 GRIA4

1.42e-0424973CID006437837
DrugpD 8

GRIA1 GRIA3 GRIA4

1.42e-0424973CID000656948
DrugNs102

GRIA1 GRIA3 GRIA4

1.61e-0425973CID005311098
DrugAC1NBNXJ

MYO6 SMS

1.78e-045972CID004470983
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; PC3; HT_HG-U133A

TIGAR U2SURP DNAJB4 IVNS1ABP SCN9A ASPM

1.79e-041939762049_DN
Drug17-hydroxyprogesterone

MYO6 GRIA1 GRIA3 GRIA4 NR3C2

1.84e-04123975CID000006238
DrugThiamphenicol [15318-45-3]; Up 200; 11.2uM; PC3; HT_HG-U133A

GTPBP4 KMT2B U2SURP IVNS1ABP ZFYVE9 SOS2

2.00e-041979761826_UP
DrugPropantheline bromide [50-34-0]; Down 200; 9uM; HL60; HT_HG-U133A

PRUNE2 TIGAR DNAJB4 AFF1 CEP152 SOS2

2.05e-041989763013_DN
DrugMethazolamide [554-57-4]; Up 200; 17uM; PC3; HT_HG-U133A

PRUNE2 AKAP5 HAP1 GRIA4 LIG3 AFF1

2.11e-041999765794_UP
DrugProtoveratrine A [143-57-7]; Up 200; 5uM; PC3; HT_HG-U133A

GPM6A KMT2B HAP1 NLRP3 MED25 MBD4

2.11e-041999766618_UP
DrugAcebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HT_HG-U133A

PRUNE2 AKAP5 HAP1 LIG3 AFF1 SOS2

2.11e-041999766631_UP
DrugIsopropamide iodide [71-81-8]; Down 200; 8.4uM; PC3; HT_HG-U133A

GTPBP4 KMT2B MYO6 DNAJB4 SEC22A SOS2

2.11e-041999767133_DN
DrugFolic acid [59-30-3]; Up 200; 9uM; PC3; HT_HG-U133A

GTPBP4 HAP1 SEC22A TBC1D9 MED25 SOS2

2.11e-041999765844_UP
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A

CDHR2 ASH1L CNKSR2 PDE10A ATP10A R3HCC1L

2.17e-042009763735_UP
DrugAC1NUW3V

GRIA1 GRIA3 GRIA4

2.53e-0429973CID005462126
Drugrufinamide

GRIA1 GRIA3 GRIA4

2.53e-0429973CID000129228
Drugbenzamil

GRIA4 SCN9A ASPM NR3C2

2.55e-0472974CID000108107
DrugAdoDatad

MYO6 SMS

2.66e-046972CID003081160
DrugM2 t

MYO6 SMS

2.66e-046972CID000167321
DrugAC1L9FMM

HAP1 GRIA1 GRIA3 GRIA4

2.69e-0473974CID000444055
DrugLY293558

GRIA1 GRIA3 GRIA4

2.80e-0430973CID000127894
DrugAC1L32TU

GRIA1 GRIA3 GRIA4

2.80e-0430973CID000107831
Drug4-methylglutamic acid

GRIA1 GRIA3 GRIA4

3.09e-0431973CID000005365
DrugKW-6002

GRIA1 GRIA3 GRIA4

3.40e-0432973CID005311037
Drugwillardine

GRIA1 GRIA3 GRIA4

3.40e-0432973CID000005123
Drugalpha-methyl-4-carboxyphenylglycine

GRIA1 GRIA3 GRIA4

3.40e-0432973CID000001222
DiseaseAutosomal recessive primary microcephaly

CENPE ASPM CEP152

1.30e-0515923cv:C3711387
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA1 GRIA3 GRIA4

1.59e-0516923DOID:331 (implicated_via_orthology)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TLK2 KMT2B GRIA1

1.93e-0517923DOID:0060307 (is_implicated_in)
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX12P DDX11L8

2.88e-053922DOID:0060535 (implicated_via_orthology)
DiseaseHypoactive Sexual Desire Disorder

GRIA1 GRIA3

1.43e-046922C0020594
DiseaseSexual Arousal Disorder

GRIA1 GRIA3

1.43e-046922C0036902
DiseaseFrigidity

GRIA1 GRIA3

1.43e-046922C0016722
DiseasePsychosexual Disorders

GRIA1 GRIA3

1.43e-046922C0033953
DiseaseOrgasmic Disorder

GRIA1 GRIA3

1.43e-046922C0029261
DiseaseKartagener Syndrome

OFD1 DNAH1 HYDIN

1.79e-0435923C0022521
DiseasePolynesian Bronchiectasis

OFD1 DNAH1 HYDIN

1.79e-0435923C4317124
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

OFD1 DNAH1 HYDIN

1.79e-0435923C4551906
DiseasePrimary Ciliary Dyskinesia

OFD1 DNAH1 HYDIN

4.31e-0447923C4551720
Diseaseserum selenium measurement

MED9 MED25 CEP152

6.14e-0453923EFO_0005266
Diseaseneurodegenerative disease (implicated_via_orthology)

GRIA1 GRIA3 GRIA4 LATS1

1.12e-03145924DOID:1289 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

MRC1 TIGAR LIG3 N4BP2 BRD4 FIP1L1 AFF1 NR3C2

1.18e-03670928EFO_0006335, EFO_0006336
DiseaseSeckel syndrome

CENPE CEP152

2.13e-0322922C0265202
DiseasePrimary microcephaly

ASPM CEP152

2.13e-0322922C0431350
DiseaseAutosomal Recessive Primary Microcephaly

ASPM CEP152

2.13e-0322922C3711387
Diseasebipolar disorder

TMEM63C TWF2 CNKSR2 PDE10A PBRM1 CDC25B SMYD3

2.21e-03577927MONDO_0004985
Diseaseplatelet reactivity measurement, response to clopidogrel

PDE10A NR3C2

2.33e-0323922EFO_0004985, GO_1903493
Diseasehypertension

MYO1D MYO6 PBRM1 NR3C2 SOS2

2.78e-03307925EFO_0000537

Protein segments in the cluster

PeptideGeneStartEntry
QARKMCNYDKILATK

ASH1L

1806

Q9NR48
KIKCDMLRYIQESKE

CEP152

1276

O94986
DKYDRMKTCLLMRQQ

ANKRD11

2596

Q6UB99
AKIICKTFKMSEERR

CTAGE4

191

Q8IX94
AKIICKTFKMSEERR

CTAGE6

191

Q86UF2
AKIICKTFKMSEERR

CTAGE8

191

P0CG41
AKIICKTFKMSEERR

CTAGE9

191

A4FU28
AKIICKTFKMSEERR

CTAGE15

191

A4D2H0
RYKKPMKVDSICNLD

HTR3E

151

A5X5Y0
KCKPMSYEEKRQLSL

BRD4

606

O60885
NCNREYDLLMKEKSR

CCDC171

161

Q6TFL3
RMCTVIKRQKQSLEY

GTPBP4

136

Q9BZE4
KRLIEMTAEYACTRK

ACAD9

316

Q9H845
ITRMFKVKKLCSDRN

ARL14

136

Q8N4G2
ELQCLALRKDSKMYK

CARD9

326

Q9H257
EIYKKTCNKMENRLL

CC2D2B

206

Q6DHV5
KREEYMQMRESCIKL

ASPM

1721

Q8IZT6
RYKRSKLERQMNCDV

ATP10A

296

O60312
NCREEKKSSTKLRMD

R3HCC1L

81

Q7Z5L2
KRMIKRACEQLSSRY

RBM43

306

Q6ZSC3
LRAEMCQKLKFFKDT

OFD1

211

O75665
LCESRYNESDKQMKK

PBRM1

1256

Q86U86
RTNYIKELRKMVTKC

NR3C2

896

P08235
KSRKVIEQRCMRYNL

MIS18BP1

656

Q6P0N0
ILKADMLKCVRREYK

MAGEB6

216

Q8N7X4
KLKMDRVKQVCGDYL

IVNS1ABP

111

Q9Y6Y0
DRIYKTKECKMRITA

MIPOL1

246

Q8TD10
CQKESNYIRLKRAKM

LATS1

686

O95835
CRMQKYEDIKSKEEQ

GPM6A

246

P51674
KKCYQMIDRRLRKNL

ATCAY

251

Q86WG3
KKSYDNEKRLMAKCR

CFAP58

51

Q5T655
RMAKRVRKDYKYVQC

TMEM63C

351

Q9P1W3
FCYKSRAESKRMKLT

GRIA3

846

P42263
FCYKSRAEAKRMKLT

GRIA4

836

P48058
EKLCRFIMSVKKNYR

PDE10A

496

Q9Y233
ISKERLSYKEAMGRC

EVPL

1986

Q92817
QKIKKANECASRLMY

FAM47B

496

Q8NA70
KAYCEKQKRIRMGLE

FIP1L1

186

Q6UN15
RMIESRQKRKKKAYC

NSMCE2

196

Q96MF7
EKDLVMYSKCQRLFR

CDC25B

306

P30305
CEVRVLMLLYSSKKK

MED25

506

Q71SY5
VYRKCDKIEARKMER

KMT2B

1001

Q9UMN6
KCMFEKLERARATTK

LIG3

141

P49916
RTKNELLQKYKSLCM

MED9

126

Q9NWA0
MSEKKRCKRILEQAF

PROSER1

111

Q86XN7
KKAKLLCMQRQDEYE

ARHGAP29

326

Q52LW3
MQAKYRECITKKEEL

DNAH1

3091

Q9P2D7
IYSGCTKRMKISRKR

DNAJB4

171

Q9UDY4
CVRKSYNRKLQAMKA

CDHR2

1176

Q9BYE9
RKNTDKEYNKCEMLD

HYDIN

1516

Q4G0P3
TICRLKLEKMYSKTN

DEFB112

6

Q30KQ8
QRCRMYGAETEKLQK

HAP1

396

P54257
KVQRYCEKSMISRKL

DDX11L8

496

A8MPP1
LFKVQRYCEKSMISR

DDX12P

511

Q92771
SKRNKDVDMLCDTLY

HAUS3

501

Q68CZ6
ERQKEKASMLCFKRR

AKAP5

26

P24588
RILKMQYCTNISKKA

FBXL13

661

Q8NEE6
LSKRGIKSRYKDCSM

MBD4

146

O95243
LMTADRKDYEKICLK

IGFN1

171

Q86VF2
IEFCYKSRSESKRMK

GRIA1

826

P42261
QECRKYFKMLSRKLA

SEC22A

31

Q96IW7
LNFKRRKMCYKKLEE

RYK

186

P34925
KCSRIKELLKRYSEM

CENPE

2096

Q02224
SRKDCQMALKRVDYA

MED11

86

Q9P086
KEKETMDNARAFCKR

MRC1

816

P22897
LEYLSRISICKMKKD

NLRP3

121

Q96P20
YVKVSLMCDGRRLKK

SYT9

391

Q86SS6
KYMRKTCGDVLDNLK

SMS

231

P52788
CKDMTVKYDSRLRER

TIGAR

76

Q9NQ88
YRLKEKFVMRKIQIC

SOS2

486

Q07890
CYQMIDRRLRKNLKS

PRUNE2

2981

Q8WUY3
KYEECKDLLKSMLRN

NBPF12

601

Q5TAG4
TKRCNLREKISKYMD

MITD1

56

Q8WV92
CYLKEMKNLRKLVFS

PRAMEF14

226

Q5SWL7
MLSKKVSRCFRKYTE

SAMD9L

1291

Q8IVG5
KKRRCSSYLLSEDML

SCN9A

666

Q15858
CYLKEMKNLRKLVFS

PRAMEF1

226

O95521
KEKLMRCSQCRVAKY

SMYD3

56

Q9H7B4
KVCIVQKRDTEKMYA

STK32C

106

Q86UX6
SKYSEMSEEKRAKLR

U2SURP

831

O15042
LEKYKERLNRCVTMS

TLK2

256

Q86UE8
AMFRCKKDIAIKYSR

AFF1

1061

P51825
TKMEYKLSFIKRCND

CNKSR2

931

Q8WXI2
KVNRKEDYSRCLQIM

ZNF451

731

Q9Y4E5
DAKKCRKVYGMERRD

SLC2A4RG

356

Q9NR83
AKKSLKRDMDRASYV

ZIK1

141

Q3SY52
NLDIKYKERSTCMKE

WDR49

581

Q8IV35
CMYRTEKTRELVLKG

TBC1D9

501

Q6ZT07
NRIKDSCVKADKMTR

SNX5

221

Q9Y5X3
LKEELKSMQRCYEKE

UACA

1131

Q9BZF9
ERKYSRKKTEYMNVC

ZNF658

156

Q5TYW1
RKKTEYMNVCEKLQL

ZNF658

161

Q5TYW1
RNSYKKNICVDMLRD

TTC29

61

Q8NA56
KRLDGCVYAIKRSMK

WEE2

231

P0C1S8
ASCRLRKMGYTKEEE

SNRNP48

76

Q6IEG0
IKERMLYSSCKSRLL

TWF2

266

Q6IBS0
KCKLLYMDRKEARVC

ZFYVE9

736

O95405
KKRQLMTSCDESKRF

ZRANB3

531

Q5FWF4
TYIRSSLDICRKMEK

ZBTB8B

116

Q8NAP8
YKAMKRRSKDTCIVI

MYO1D

86

O94832
KYRAEACIKMQKTIR

MYO6

811

Q9UM54
QKRMECYSKAKEAYR

N4BP2

1631

Q86UW6