Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentRAVE complex

DMXL2 DMXL1

5.24e-053882GO:0043291
DomainRav1p_C

DMXL2 DMXL1

2.14e-052872IPR022033
DomainRav1p_C

DMXL2 DMXL1

2.14e-052872PF12234
DomainROR_rcpt

RORB RORC

6.42e-053872IPR003079
DomainHydrolase_4

ABHD17B ABHD17C

7.56e-049872IPR022742
DomainHydrolase_4

ABHD17B ABHD17C

7.56e-049872PF12146
DomainPeptidase_S9

ABHD17B ABHD17C

1.15e-0311872PF00326
DomainPeptidase_S9

ABHD17B ABHD17C

1.15e-0311872IPR001375
DomainPeptidase_M1

RNPEP NPEPPS

1.37e-0312872IPR001930
DomainAA_permease_2

SLC7A8 SLC7A13

1.62e-0313872PF13520
DomainPeptidase_M1

RNPEP NPEPPS

1.62e-0313872PF01433
DomainAA/rel_permease1

SLC7A8 SLC7A13

1.62e-0313872IPR002293
DomainPeptidase_M1_N

RNPEP NPEPPS

1.62e-0313872IPR014782
DomainApc4_WD40_dom

WDHD1 WDR35

3.86e-0320872IPR024977
DomainANAPC4_WD40

WDHD1 WDR35

3.86e-0320872PF12894
Domain-

PLXNA3 DMXL2 WDR75 WDHD1 WDR35 DMXL1

4.62e-033338762.130.10.10
DomainAA-permease/SLC12A_dom

SLC7A8 SLC7A13

4.66e-0322872IPR004841
DomainAA_permease

SLC7A8 SLC7A13

4.66e-0322872PF00324
DomainWD40/YVTN_repeat-like_dom

PLXNA3 DMXL2 WDR75 WDHD1 WDR35 DMXL1

4.76e-03335876IPR015943
DomainP-loop_NTPase

TANC2 ABCA1 ERCC2 MYO7A DQX1 GET3 PEX1 AK9 RHOT1 DNAH1

5.99e-038488710IPR027417
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TANC2 ZNF219 WDR75 WDHD1 MYO7A DPY30 C5 CBL NDUFS1 TFE3

6.16e-06638901031182584
Pubmed

Cutting edge: Ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt.

USP4 RORC

6.62e-06290225821221
Pubmed

Association of phosphatidylinositol 3-kinase with the proto-oncogene product Cbl upon CD38 ligation by a specific monoclonal antibody in THP-1 cells.

PIK3R1 CBL

6.62e-0629028941725
Pubmed

CD38-mediated growth suppression of B-cell progenitors requires activation of phosphatidylinositol 3-kinase and involves its association with the protein product of the c-cbl proto-oncogene.

PIK3R1 CBL

6.62e-0629028695807
Pubmed

Role of phosphoinositide 3-kinase and the Cbl adaptor protein in coupling the alpha4beta1 integrin to mitogen-activated protein kinase signalling.

PIK3R1 CBL

6.62e-06290210620516
Pubmed

Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.

PIK3R1 CBL

6.62e-06290227884787
Pubmed

c-Cbl is tyrosine-phosphorylated by interleukin-4 and enhances mitogenic and survival signals of interleukin-4 receptor by linking with the phosphatidylinositol 3'-kinase pathway.

PIK3R1 CBL

6.62e-0629029414268
Pubmed

Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism.

PIK3R1 CBL

6.62e-0629028702998
Pubmed

Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.

PIK3R1 CBL

6.62e-0629028995243
Pubmed

Specific association of phosphatidylinositol 3-kinase with the protooncogene product Cbl in Fc gamma receptor signaling.

PIK3R1 CBL

6.62e-0629028612729
Pubmed

Shp-2 mediates v-Src-induced morphological changes and activation of the anti-apoptotic protein kinase Akt.

PIK3R1 CBL

6.62e-06290210918571
Pubmed

The protein product of the proto-oncogene c-cbl forms a complex with phosphatidylinositol 3-kinase p85 and CD19 in anti-IgM-stimulated human B-lymphoma cells.

PIK3R1 CBL

6.62e-0629028896416
Pubmed

c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.

PIK3R1 CBL

6.62e-06290220133944
Pubmed

Regulation of dendritic spines, spatial memory, and embryonic development by the TANC family of PSD-95-interacting proteins.

TANC2 TANC1

6.62e-06290221068316
Pubmed

Fc receptor-mediated platelet activation is dependent on phosphatidylinositol 3-kinase activation and involves p120(Cbl).

PIK3R1 CBL

6.62e-0629029890943
Pubmed

A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.

WDHD1 PIK3R1 NPEPPS PRPF8

9.55e-065190426839216
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

DMXL2 CTU2 FAT1 ERCC2 COL10A1 WDHD1 USP4 CBL SPAG6 NDUFS1

1.20e-05689901036543142
Pubmed

Identification of genes concordantly expressed with Atoh1 during inner ear development.

MYO7A RORC SPAG6

1.58e-051990321519551
Pubmed

c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment.

PIK3R1 CBL

1.98e-05390219861161
Pubmed

Patients with severe asthenoteratospermia carrying SPAG6 or RSPH3 mutations have a positive pregnancy outcome following intracytoplasmic sperm injection.

SPAG6 DNAH1

1.98e-05390232124190
Pubmed

Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells.

PIK3R1 CBL

1.98e-0539027791764
Pubmed

Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes liquid-liquid phase separation.

TANC2 TANC1

1.98e-05390238092135
Pubmed

Altered Activity and Expression of Cytosolic Peptidases in Colorectal Cancer.

RNPEP NPEPPS

1.98e-05390226078706
Pubmed

Role of Cbl in shear-activation of PI 3-kinase and JNK in endothelial cells.

PIK3R1 CBL

1.98e-05390211944898
Pubmed

Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis.

PIK3R1 CBL

1.98e-05390216798838
Pubmed

Phosphorylation and nuclear exclusion of the forkhead transcription factor FKHR after epidermal growth factor treatment in human breast cancer cells.

PIK3R1 CBL

1.98e-05390211030146
Pubmed

Dynamic expression of Lgr6 in the developing and mature mouse cochlea.

MYO7A LGR6

1.98e-05390226029045
Pubmed

Requirements for pYXXM motifs in Cbl for binding to the p85 subunit of phosphatidylinositol 3-kinase and Crk, and activation of atypical protein kinase C and glucose transport during insulin action in 3T3/L1 adipocytes.

PIK3R1 CBL

1.98e-05390215581361
Pubmed

Biochemistry. Ubiquitination--more than two to tango.

UBE2G2 CBL

1.98e-05390211032556
Pubmed

Yeast two-hybrid in vivo association of the Src kinase Lyn with the proto-oncogene product Cbl but not with the p85 subunit of PI 3-kinase.

PIK3R1 CBL

1.98e-0539029160881
Pubmed

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

PIK3R1 CBL

1.98e-05390211087752
Pubmed

Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase.

PIK3R1 CBL

1.98e-0539029259313
Pubmed

c-Cbl localizes to actin lamellae and regulates lamellipodia formation and cell morphology.

PIK3R1 CBL

1.98e-05390210633073
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 FAT1 ERCC2 ZNF219 ARSB PIK3R1 PEX1 TANC1 SIGLEC1 AGBL1 TENT2 RHOT1

3.07e-051116901231753913
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

LCA5 PANK2 PIK3R1 CLN5 PEX1 RORB

3.30e-0523390632290105
Pubmed

c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl.

PIK3R1 CBL

3.96e-05490217237826
Pubmed

c-Cbl is a suppressor of the neu oncogene.

PIK3R1 CBL

3.96e-05490210940298
Pubmed

Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages.

PIK3R1 CBL

3.96e-0549028947469
Pubmed

Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association.

PIK3R1 CBL

3.96e-0549029988765
Pubmed

Protein kinase C activation inhibits tyrosine phosphorylation of Cbl and its recruitment of Src homology 2 domain-containing proteins.

PIK3R1 CBL

3.96e-05490210358153
Pubmed

Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts.

PIK3R1 CBL

3.96e-05490210391678
Pubmed

ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization.

ABHD17B ABHD17C

3.96e-05490226701913
Pubmed

CD16-mediated activation of phosphatidylinositol-3 kinase (PI-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc, pp36 and p85 PI-3K subunit.

PIK3R1 CBL

3.96e-0549029541596
Pubmed

Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk.

PIK3R1 CBL

3.96e-05490211042121
Pubmed

FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival.

PIK3R1 CBL

6.59e-05590218374639
Pubmed

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

PIK3R1 CBL

6.59e-0559027544353
Pubmed

Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes.

RORC SIGLEC1

6.59e-05590226193821
Pubmed

Tyrosine phosphorylation of p120cbl in BCR/abl transformed hematopoietic cells mediates enhanced association with phosphatidylinositol 3-kinase.

PIK3R1 CBL

6.59e-0559029174058
Pubmed

Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.

PIK3R1 CBL

6.59e-05590224470255
Pubmed

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase.

PIK3R1 CBL

6.59e-0559027642581
Pubmed

The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase.

PIK3R1 CBL

6.59e-0559029223670
Pubmed

Hck enhances the adherence of lipopolysaccharide-stimulated macrophages via Cbl and phosphatidylinositol 3-kinase.

PIK3R1 CBL

6.59e-05590210799548
Pubmed

Involvement of Src-homology-2-domain-containing protein-tyrosine phosphatase 2 in T cell activation.

PIK3R1 CBL

6.59e-0559028647120
Pubmed

Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization.

ABHD17B ABHD17C

6.59e-05590228521134
Pubmed

The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.

PIK3R1 CBL

6.59e-0559029013636
Pubmed

Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.

PIK3R1 CBL

6.59e-05590224113870
Pubmed

Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development.

COL10A1 DNMT3B

6.59e-05590229637597
Pubmed

p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells.

PIK3R1 CBL

6.59e-0559029918857
Pubmed

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

PIK3R1 CBL

9.87e-05690211406619
Pubmed

T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.

PIK3R1 CBL

9.87e-05690211418612
Pubmed

Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans.

LIG1 ERCC2

9.87e-05690218709642
Pubmed

Novel compound heterozygous mutations in UHRF1 are associated with atypical immunodeficiency, centromeric instability and facial anomalies syndrome with distinctive genome-wide DNA hypomethylation.

LIG1 DNMT3B

9.87e-05690236458887
Pubmed

M-CSF regulates the cytoskeleton via recruitment of a multimeric signaling complex to c-Fms Tyr-559/697/721.

PIK3R1 CBL

9.87e-05690217420256
Pubmed

cbl-b inhibits epidermal growth factor receptor signaling.

PIK3R1 CBL

9.87e-05690210086340
Pubmed

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.

PIK3R1 CBL

9.87e-0569029130710
Pubmed

Phosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicity.

PIK3R1 CBL

9.87e-0569029234717
Pubmed

Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase.

PIK3R1 CBL

9.87e-05690216219545
Pubmed

USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31.

USP4 PRPF8

9.87e-05690228088760
Pubmed

CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins.

PIK3R1 CBL

9.87e-05690210025673
Pubmed

p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function.

PIK3R1 CBL

9.87e-05690219190244
Pubmed

Cortical RORβ is required for layer 4 transcriptional identity and barrel integrity.

THSD7A RORB

9.87e-05690232851975
Pubmed

Immunohistochemical characterization of the orphan nuclear receptor ROR alpha in the mouse nervous system.

RORB RORC

9.87e-05690214966198
Pubmed

Deficient tyrosine phosphorylation of c-Cbl and associated proteins in phorbol ester-resistant EL4 mouse thymoma cells.

PIK3R1 CBL

9.87e-0569029115297
Pubmed

Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl.

PIK3R1 CBL

9.87e-05690215556646
Pubmed

Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells.

PIK3R1 CBL

9.87e-0569029461587
Pubmed

Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.

PIK3R1 CBL

9.87e-05690215581362
Pubmed

Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase.

PIK3R1 CBL

9.87e-0569029890970
Pubmed

Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation.

PIK3R1 CBL

1.38e-0479029233773
Pubmed

Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor.

PIK3R1 CBL

1.38e-04790211994282
Pubmed

Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif.

PIK3R1 CBL

1.38e-0479029092538
Pubmed

CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis.

PIK3R1 CBL

1.38e-04790212637493
Pubmed

CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1.

PIK3R1 CBL

1.38e-04790233512474
Pubmed

The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex.

ABCA1 PRPF8

1.38e-04790212054535
Pubmed

The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.

PIK3R1 CBL

1.38e-04790210962563
Pubmed

A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes.

PIK3R1 CBL

1.38e-0479029660791
Pubmed

SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.

PIK3R1 CBL

1.38e-04790211031258
Pubmed

Identification of PSD-95 Depalmitoylating Enzymes.

ABHD17B ABHD17C

1.38e-04790227307232
Pubmed

Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav.

PIK3R1 CBL

1.84e-04890216289966
Pubmed

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis.

IL10RA RORC

1.84e-04890225607885
Pubmed

Multiple genetic polymorphisms in the prediction of clinical outcome of metastatic colorectal cancer patients treated with first-line FOLFOX-4 chemotherapy.

DPYD ERCC2

1.84e-04890221057378
Pubmed

Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes.

PIK3R1 CBL

1.84e-04890211071869
Pubmed

Identification of Itk/Tsk Src homology 3 domain ligands.

PIK3R1 CBL

1.84e-0489028810341
Pubmed

XPC genetic polymorphisms correlate with the response to imatinib treatment in patients with chronic phase chronic myeloid leukemia.

LIG1 ERCC2

1.84e-04890220575039
Pubmed

The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

PIK3R1 CBL

1.84e-04890211133830
Pubmed

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.

USP4 PRPF8

1.84e-04890220595234
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

FAT1 WDR75 SACS SHOC1 PRPF8 SLC4A5

2.30e-0433290637433992
Pubmed

Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05.

DPYD ERCC2

2.36e-04990220385995
Pubmed

TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin.

PIK3R1 CBL

2.36e-04990215107835
Pubmed

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.

PIK3R1 CBL

2.36e-0499029489702
Pubmed

Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial.

DPYD ERCC2

2.36e-04990219858398
GeneFamilyAminopeptidases|CD molecules

RNPEP NPEPPS

1.62e-0317642104
GeneFamilyWD repeat domain containing

DMXL2 WDR75 WDHD1 WDR35 DMXL1

2.34e-03262645362
GeneFamilyAbhydrolase domain containing

ABHD17B ABHD17C

2.72e-03226424
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

TRAF3IP1 WDR35

3.24e-0324642615
GeneFamilyGeneral transcription factors|Xeroderma pigmentosum complementation groups|DNA helicases|ERCC excision repair associated

GTF2B ERCC2

3.51e-0325642565
CoexpressionGSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP

TANC2 ABCA1 NPEPPS CLN5 HIPK2 TRAPPC14 ABHD17C

5.10e-06200887M8064
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

IL10RA DPYD DMXL2 ABCA1 SLC2A9 SIGLEC1 KYNU

1.32e-07195897c172c5599379c29123340621a36bfb1fc90c2115
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

ARMC3 TRAF3IP1 MYO7A WDR35 DCDC2B AK9 DNAH1

1.46e-071988976d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 DMXL2 ABCA1 MYO7A SIGLEC1 ABHD17C

1.95e-061858964bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL10RA SLC7A8 DMXL2 ABCA1 SIGLEC1 KYNU

2.14e-061888963be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3IP1 CCNA1 DCDC2B AK9 SPAG6 DNAH1

2.35e-0619189696483adb97c81208aa513782550acd8a08b63866
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

IL10RA DPYD DMXL2 SLC2A9 SIGLEC1 KYNU

2.42e-06192896a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

IL10RA DMXL2 ABCA1 SLC2A9 SIGLEC1 KYNU

2.49e-06193896a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

IL10RA DPYD DMXL2 SLC2A9 SIGLEC1 KYNU

2.49e-0619389612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

IL10RA SLC7A8 DMXL2 SLC2A9 MYO7A SIGLEC1

2.49e-0619389631c0978ba78c9516d498aec0798902e57555e557
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

IL10RA DPYD DMXL2 SLC2A9 SIGLEC1 KYNU

2.57e-06194896c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

IL10RA DPYD DMXL2 SLC2A9 SIGLEC1 KYNU

2.64e-061958965e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellCOVID-19-lung-Macrophage_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

IL10RA DMXL2 ABCA1 MYO7A SIGLEC1 KYNU

2.72e-06196896a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA DPYD DMXL2 ABCA1 SIGLEC1 KYNU

2.72e-061968967026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA SLC7A8 DMXL2 ABCA1 SIGLEC1 KYNU

2.81e-0619789610190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA DMXL2 TMEM131L SIGLEC1 CBL KYNU

2.81e-06197896f18807124b91310fcd84238484a80ecdba684679
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA ABCA1 SLC2A9 DQX1 SIGLEC1 KYNU

2.89e-061988966a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellCOVID-19-kidney-Macrophages|kidney / Disease (COVID-19 only), tissue and cell type

IL10RA DPYD DMXL2 ABCA1 SIGLEC1 KYNU

2.89e-06198896161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARMC3 CCNA1 DCDC2B AK9 SPAG6 DNAH1

2.97e-0619989615f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellcellseq-Immune-Immune_Myeloid-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL10RA DMXL2 ABCA1 MYO7A SIGLEC1 IGFLR1

2.97e-06199896b3267d5a7ae0461f5e9e6a3ab6783317a8c42506
ToppCellcellseq-Immune-Immune_Myeloid-IM-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL10RA DMXL2 ABCA1 MYO7A SIGLEC1 IGFLR1

2.97e-0619989601dacee8bb392639d475be3cb27ba3eeff1e57f1
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 ABCA1 SLC2A9 MYO7A SIGLEC1 KYNU

3.06e-0620089678d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A8 ENGASE SLC7A13 SIGLEC1 SLC4A5

2.20e-0516889504e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ARMC3 CCNA1 DCDC2B SPAG6 DNAH1

3.07e-05180895bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRN1L DPYD RADIL IGSF9B LGR6

3.32e-05183895b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCelldroplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRN1L DPYD RADIL IGSF9B LGR6

3.32e-0518389519e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 DMXL2 MYO7A SIGLEC1 ABHD17C

3.40e-051848958fa30789c9d583188667cf375d2218e392dd40bc
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

DMXL2 ARSB MYO7A NPAS3 SIGLEC1

3.49e-05185895ab5704b96f1d368911308797d10c7c52766ab134
ToppCelldroplet-Marrow-BM-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIG1 ARSB NPEPPS DPY30 ABHD17C

3.68e-051878956be99f71532b7d679d1287ea1bb08245d9538db7
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL10RA MYO7A NPAS3 SIGLEC1 KYNU

3.68e-0518789539b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

SLC7A8 ABCA1 MYO7A SIGLEC1 DISP1

3.68e-0518789559e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

LCA5 TRAF3IP1 DCDC2B AK9 SPAG6

3.77e-051888958f30535a32968a81a304315a49c0d90a77d36948
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

HIPK2 TMEM131L IGSF9B LGR6 CBL

3.77e-051888959ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRN1L DPYD RADIL IGSF9B LGR6

3.87e-05189895cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRN1L DPYD RADIL IGSF9B LGR6

3.87e-05189895102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCellControl|World / Disease state, Lineage and Cell class

DMXL2 ABCA1 HIPK2 KYNU ABHD17C

3.87e-05189895fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRN1L DPYD RADIL IGSF9B LGR6

3.87e-051898956e83bf855d4771885b60bb8992df2f9b508eef97
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA ABCA1 MYO7A NPAS3 SIGLEC1

3.97e-05190895f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA1 THSD7A ABHD17B MYO7A NPAS3

3.97e-05190895a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA1 THSD7A ABHD17B MYO7A NPAS3

3.97e-051908950bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA1 THSD7A ABHD17B MYO7A NPAS3

3.97e-0519089526e2237f65cb43723c5da853831b40df2982d6e4
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

IL10RA DPYD SLC2A9 SIGLEC1 KYNU

4.07e-05191895e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMC3 TRAF3IP1 CCNA1 AK9 SPAG6

4.07e-05191895acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell5'-Adult-LymphNode-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYD PANK2 TMEM131L TRAPPC14 IGFLR1

4.07e-05191895e5c41c3054ead03597c136eaccaf9822e6bb9d1a
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 THSD7A ABHD17B MYO7A NPAS3

4.07e-0519189548823a97c38263f2c6e58348214f5b62773a6368
ToppCell5'-Adult-LymphNode-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYD PANK2 TMEM131L TRAPPC14 IGFLR1

4.07e-051918957e24175c7fabe5ea0b22b73173da4c3a666e5eb8
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 THSD7A ABHD17B MYO7A NPAS3

4.07e-051918950eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

IL10RA DPYD SLC2A9 SIGLEC1 KYNU

4.17e-051928957be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

DMXL2 SLC2A9 HIPK2 SIGLEC1 KYNU

4.27e-05193895cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

IL10RA SLC7A8 MYO7A NPAS3 SIGLEC1

4.27e-0519389564d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 SLC2A9 HIPK2 SIGLEC1 KYNU

4.38e-0519489569cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

IL10RA SLC7A8 DMXL2 ABCA1 SIGLEC1

4.38e-05194895800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 ABCA1 ARSB SIGLEC1 KYNU

4.49e-051958959d649ac7d2af313481069c95349efc0c68449e2b
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

IL10RA DMXL2 ABCA1 SIGLEC1 KYNU

4.49e-05195895148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA SLC7A8 DMXL2 ABCA1 SIGLEC1

4.49e-05195895c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

DPYD DMXL2 ABCA1 HIPK2 KYNU

4.49e-0519589546ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

DMXL2 ABCA1 SLC2A9 SIGLEC1 KYNU

4.49e-0519589555e25f702af19146a161861cfd15f40bbda1dc35
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

IL10RA DPYD DMXL2 CBL KYNU

4.60e-0519689504d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA DPYD DMXL2 CBL KYNU

4.60e-05196895cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellCOVID-19-lung-Macrophage_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA DMXL2 ABCA1 SIGLEC1 KYNU

4.60e-051968951b7928f4eee94d4bb6ea410bab68a471dba12979
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA DPYD DMXL2 SIGLEC1 KYNU

4.71e-05197895e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellCOVID-19-kidney-Macrophages|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA DPYD DMXL2 ABCA1 KYNU

4.71e-051978953912301018d0863144dcfac8d1fa8adc081748d7
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

IL10RA DPYD DMXL2 SIGLEC1 KYNU

4.71e-05197895a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 SLC2A9 SIGLEC1 CBL KYNU

4.83e-05198895e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA DPYD DMXL2 SIGLEC1 KYNU

4.83e-05198895ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellCOVID-19-Myeloid|COVID-19 / group, cell type (main and fine annotations)

DPYD DMXL2 ABCA1 SIGLEC1 KYNU

4.83e-0519889533f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA DMXL2 ABCA1 SIGLEC1 KYNU

4.83e-05198895dbae6a58cb3ce8612755fbdba6194b70b35f258a
ToppCellImmune|World / Lineage, Cell type, age group and donor

IL10RA DMXL2 SIGLEC1 CBL KYNU

4.83e-0519889565681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

IL10RA DMXL2 SLC2A9 SIGLEC1 KYNU

4.83e-051988959bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA1 MYO7A NPAS3 SIGLEC1 KYNU

4.83e-05198895c7dbf24caae5c4ef285845d13055de9e07281bb3
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DMXL2 ABCA1 SLC2A9 SIGLEC1 KYNU

4.83e-051988950b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA SLC7A8 DMXL2 ABCA1 SIGLEC1

4.94e-05199895f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC7A8 DMXL2 ABCA1 MYO7A SIGLEC1

4.94e-05199895b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA DMXL2 ABCA1 SIGLEC1 KYNU

4.94e-051998959df2c79904dacf029ec9df1f1cde72d871189a82
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA SLC7A8 DMXL2 ABCA1 SIGLEC1

4.94e-051998955ceeed92f831d068ff4bb3994f420002338330e7
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC7A8 DMXL2 ABCA1 MYO7A SIGLEC1

4.94e-05199895c0dcdda30485bb920d3706dcfb06f11b76b6ea37
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC7A8 DMXL2 ABCA1 SIGLEC1 KYNU

4.94e-05199895667b8b47a5b388506e3177b46747267fad8024f6
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPYD DMXL2 ABCA1 SIGLEC1 KYNU

4.94e-05199895155b03b859157013e9142e9248551369127d9204
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA DPYD DMXL2 CBL KYNU

5.06e-05200895881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA SLC2A9 NPAS3 SIGLEC1 KYNU

5.06e-05200895ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal|3m / Sample Type, Dataset, Time_group, and Cell type.

SLC7A8 ARMC3 SUCO SPAG6 SLC4A5

5.06e-05200895ce012d738cbec1afdd6af0e10e94b2b6c17b036e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

SLC7A8 LCA5 ARMC3 SPAG6 SLC4A5

5.06e-05200895177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IL10RA SLC7A8 ABCA1 MYO7A SIGLEC1

5.06e-05200895af743dfef7e7cfaef1c494999757123f93a213e3
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 THSD7A PIK3R1 NPAS3

1.12e-0412489436dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

NRN1L ADGRG5 ZNF219 DNAH1

1.64e-04137894b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNA1 AK9 SPAG6 SDR9C7

2.39e-04151894e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

UBR2 CTU2 CYP4F3 DNAH1

2.39e-04151894b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNA1 AK9 SPAG6 SDR9C7

2.39e-04151894633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

DMXL2 ABCA1 PEX1 SIGLEC1

2.51e-041538945424494ea1f09542799045a875cc3eac13de5079
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL10RA ADGRG5 SIGLEC1 KYNU

2.51e-04153894c81a88d3f707487c511020d3960a1c41e706c6a0
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGRG5 TRAF3IP1 SACS AK9

2.70e-04156894a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERCC2 ZNF219 WDR35 TRAPPC14

2.77e-04157894f896997490bb2eec598c6581f161220e70f9a991
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ERCC2 ZNF219 WDR35 TRAPPC14

2.77e-0415789414a8516346a89a89f1119b744625bd9844a74a03
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IL10RA ADGRG5 MYO7A SIGLEC1

2.97e-041608947f1b58641ba149d20420fafad34ba78a65a2c701
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RADIL RORB IGSF9B AGBL1

2.97e-04160894778faada072e3abfa76a9a06fd4885fb63de7902
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABHD17B SZT2 MYO7A ABHD17C

3.12e-0416289464353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC7A8 SACS PIK3R1 DNMT3B

3.19e-041638944dfd408aa700e307478ee35f6b902f68719d8d9e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

FAT1 TACC2 TMC4 AGBL1

3.19e-04163894e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL10RA ARSB WDHD1 KYNU

3.19e-041638947af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ARMC3 CCNA1 DCDC2B SPAG6

3.34e-04165894731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

IL10RA SLC2A9 MYO7A SIGLEC1

3.42e-04166894be284e2e596390f05305c7bcfc316f87b963fc0b
Diseasecomplement C5B-C6 complex measurement

NPEPPS C5

2.63e-053882EFO_0020279
DiseaseEarly onset schizophrenia

NDUFS1 DNMT3B

2.63e-053882C1656427
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 PIK3R1 DNMT3B

7.96e-0528883DOID:5409 (is_implicated_in)
Diseasepantothenate measurement

ABCA1 PANK2

2.43e-048882EFO_0021034
DiseaseMajewski Syndrome

TRAF3IP1 WDR35

7.82e-0414882C0024507
Diseaseinherited metabolic disorder (is_implicated_in)

LIG1 NDUFS1

9.00e-0415882DOID:655 (is_implicated_in)
DiseaseAntibody Deficiency Syndrome

C5 DNMT3B

1.16e-0317882C0003257
DiseaseColorectal Carcinoma

LIG1 DPYD GTF2B FAT1 ABCA1 ERCC2 SACS LGR6

1.19e-03702888C0009402
Diseaseinsulin sensitivity measurement, body mass index

NPAS3 AGBL1

1.45e-0319882EFO_0004340, EFO_0004471
DiseaseColorectal Neoplasms

DPYD FAT1 ABCA1 ERCC2 LGR6

1.46e-03277885C0009404
Diseaseacute myeloid leukemia (is_implicated_in)

ERCC2 CBL DNMT3B

2.05e-0384883DOID:9119 (is_implicated_in)
DiseaseImmunologic Deficiency Syndromes

C5 DNMT3B

2.14e-0323882C0021051
Diseasetotal blood protein measurement

SLC7A8 TMEM131L USP4 SIGLEC1 KYNU DNAH1

2.28e-03449886EFO_0004536
DiseaseHead Neoplasms

DPYD FAT1

2.33e-0324882C0018675
DiseaseUpper Aerodigestive Tract Neoplasms

DPYD FAT1

2.33e-0324882C0887900
DiseaseCancer of Head

DPYD FAT1

2.33e-0324882C0751177
DiseaseNeck Neoplasms

DPYD FAT1

2.52e-0325882C0027533
DiseaseCancer of Neck

DPYD FAT1

2.52e-0325882C0746787
Diseasecerebellum cortex volume change measurement, age at assessment

PIK3R1 ABHD17C

2.73e-0326882EFO_0008007, EFO_0021497
DiseaseAntiglaucoma preparations and miotics use measurement

ABCA1 THSD7A

2.73e-0326882EFO_0009944
Diseaseblood chromium measurement

NHLRC2 LGR6

2.73e-0326882EFO_0007579

Protein segments in the cluster

PeptideGeneStartEntry
VYFLDKILQKSPLPP

RNPEP

536

Q9H4A4
LEYEAPKLYPAIPAA

DNMT3B

556

Q9UBC3
ALVFSLIVPPFGKYP

ABCA1

1361

O95477
EKLPLPPAIQRYILF

ASB15

561

Q8WXK1
SAKPELPLFYTPIDL

DPYD

516

Q12882
EPILPSLQKIYPESF

TENT2

346

Q6PIY7
NAIPPILDLLKSEYP

ARMC3

191

Q5W041
TEIDSIPPLPLYALL

DMXL2

1421

Q8TDJ6
DSVPPLPLYALLAAD

DMXL1

1401

Q9Y485
PSRPFKLPKSYAALI

DISP1

171

Q96F81
TAPPDYDILLPLFRL

AGBL1

66

Q96MI9
PYKNLPRAIFISIPL

SLC7A8

261

Q9UHI5
YLLLFKDPAQAQPLP

RADIL

351

Q96JH8
PPVFAKPLYEASLLL

FAT1

1876

Q14517
PLTEKLLSKPPFRYL

TRAF3IP1

21

Q8TDR0
NKFSPLPLKYIRPVL

HIPK2

291

Q9H2X6
LPLPACLNPLLYLLF

LGR6

816

Q9HBX8
FPIDKPPSFRALLYK

PLXNA3

771

P51805
DLTPEYLFPLLKIPP

RHOT1

281

Q8IXI2
LFVPPVLNPLIYSAK

OR51I2

281

Q9H344
LSPLDIYPKILDFHP

ERCC2

461

P18074
SRNLKYPVLPLLPDF

LCA5

481

Q86VQ0
YPVLPLLPDFESKLH

LCA5

486

Q86VQ0
LPSVLLFKKPSPFIF

IL10RA

266

Q13651
FNVPYPLPKIDLIAI

NPEPPSL1

296

A6NEC2
FKRYLLDLPNPVIPA

PIK3R1

186

P27986
CLYPKSFLELEAPPL

DQX1

386

Q8TE96
IKLYKDSLPPSPLLF

NHLRC2

211

Q8NBF2
PEDQKPLFAVFLPIY

OR1L1

71

Q8NH94
PFDLKNPYPLLLVNI

PANK2

376

Q9BZ23
DPIFPIYLPLKVFDN

DNAH1

236

Q9P2D7
LYIPLAKLPTPVTDF

SDR9C7

286

Q8NEX9
KDLPYLELLVPSPSL

DCDC2B

206

A2VCK2
PYKLNLVATPLFLKP

C5

351

P01031
LSLLEADPFLKYLPS

CCNA1

371

P78396
LLLLALAPPPEASQY

IGFLR1

11

Q9H665
AKLAFLPPEPTYTVL

ABHD17C

31

Q6PCB6
ALITNHPPEKPLFLY

ARSB

221

P15848
HPPEKPLFLYLALQS

ARSB

226

P15848
VNTFSALLLEPYKPP

GET3

331

O43681
LLSLPFLPDSPRYLL

SLC2A9

246

Q9NRM0
ALKNSPPYILDLLPD

CBL

76

P22681
YIKPVLFAPAAIVPK

CYP4F3

106

Q08477
RLFSLQAPVPPKIYL

ENGASE

481

Q8NFI3
RPPNPIEFLASYLLK

DPY30

76

Q9C005
ALSPPDLLPVLYLSL

LIG1

321

P18858
VDSLKTRYPDLLPFP

SACS

4531

Q9NZJ4
IQLPAKYPELFANLP

PEX1

856

O43933
FNVPYPLPKIDLIAI

NPEPPS

296

P55786
KDLPSLDPLPPYILA

CTU2

471

Q2VPK5
PAPPLLAAALALAYL

NRN1L

146

Q496H8
LPLDYRAPFLLTLEP

SZT2

756

Q5T011
ALKPFLLNPRPYLLP

AK9

371

Q5TCS8
ALEPFLYDAPPNILK

SPAG6

416

O75602
YFEPKPLLEQACLIP

THSD7A

176

Q9UPZ6
LLPLSLYPKPEALVH

TMEM131L

621

A2VDJ0
ADPLVPPQLTIKDFY

NDUFS1

681

P28331
LTPADLEVPIPKYFL

IQCA1L

111

A6NCM1
FLIEYEFLIPPSLKP

SHOC1

176

Q5VXU9
PYKPQDILLKPLLFE

TANC1

361

Q9C0D5
APYRPPDISLKPLLF

TANC2

316

Q9HCD6
FYELAKLLPLPAAIT

NPAS3

71

Q8IXF0
AALPVLDSYLAPALP

SELENOV

136

P59797
KIASKLAFLPPDPTY

ABHD17B

21

Q5VST6
SPALVPAELLAPLTY

ADGRG5

236

Q8IZF4
FPFIKITYEEIPLPI

CLN5

336

O75503
AYPAIGTPIPFDKIL

COL10A1

561

Q03692
PFPPLSYKHDTKLLI

PRPF8

826

Q6P2Q9
FDPFCYLTLPLPLKK

USP4

471

Q13107
PIVVQAAFPPLYKEL

RORC

491

P51449
PDSFYELKSQPLPLR

TFE3

61

P19532
KLTELLFPYILPPKA

SNX14

246

Q9Y5W7
PLYLPPDKAVLSLDK

TRAPPC14

551

Q8WVR3
PARLVLKDPPYFTVL

IGSF9B

411

Q9UPX0
LIYPRAPDLFPTDFK

GTF2B

291

Q00403
DLFVFKPSEPRPLYI

WDR75

606

Q8IWA0
LPRPAVAILSFKLPY

WDHD1

701

O75717
VLPPVFKLIAPLEGY

TMC4

406

Q7Z404
PEIVNTLFPPLYKEL

RORB

446

Q92753
PILKCIPLPVLYGVF

SLC4A5

946

Q9BY07
YLEPDLAEKNPPLFA

TACC2

2661

O95359
PNLSIPYKVFLSFPL

SLC7A13

386

Q8TCU3
SVLYPPDRPKLSALL

SIGLEC1

791

Q9BZZ2
KDYLVLAQPPLLLPA

SUCO

656

Q9UBS9
SAPLLPKEDPIFTYL

TTC17

186

Q96AE7
ILPFKYPAVLPEITV

RWDD2B

106

P57060
PLDPKYIDIVPLFVA

WDR35

421

Q9P2L0
AYKFPELLPLSELSP

UBR2

631

Q8IWV8
LLAYEPLGPALLLAP

ZNF219

351

Q9P2Y4
PDTQLYPDFTKLLPL

TPRX2

251

P0DV77
AILSFPLDYPLSPPK

UBE2G2

56

P60604
FYIPKIQDLPPVDLS

KYNU

46

Q16719
SYFPSIPKLLRELVP

MYO7A

2051

Q13402