| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | 1.58e-06 | 560 | 41 | 9 | GO:0001228 | |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | 1.73e-06 | 566 | 41 | 9 | GO:0001216 | |
| GeneOntologyMolecularFunction | chromatin binding | 1.50e-05 | 739 | 41 | 9 | GO:0003682 | |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | SOX9 CDX1 PER2 PRDM16 FOXN4 TFAP2A GLI1 KLF5 GLI3 PROP1 MEOX1 | 3.56e-05 | 1271 | 41 | 11 | GO:0000987 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | SOX9 CDX1 PRDM16 FOXN4 TFAP2A GLI1 KLF5 GLI3 PRDM2 PROP1 MEOX1 | 9.29e-05 | 1412 | 41 | 11 | GO:0000981 |
| GeneOntologyMolecularFunction | histone H3 methyltransferase activity | 1.00e-04 | 44 | 41 | 3 | GO:0140938 | |
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | SOX9 CDX1 PER2 PRDM16 TFAP2A GLI1 KLF5 GLI3 PRDM2 PROP1 MEOX1 | 1.25e-04 | 1459 | 41 | 11 | GO:0000977 |
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 1.61e-04 | 1244 | 41 | 10 | GO:0000978 | |
| GeneOntologyMolecularFunction | polyubiquitin modification-dependent protein binding | 2.41e-04 | 59 | 41 | 3 | GO:0031593 | |
| GeneOntologyMolecularFunction | histone H3K9 methyltransferase activity | 3.16e-04 | 13 | 41 | 2 | GO:0046974 | |
| GeneOntologyMolecularFunction | molecular adaptor activity | 3.24e-04 | 1356 | 41 | 10 | GO:0060090 | |
| GeneOntologyMolecularFunction | protein-lysine N-methyltransferase activity | 3.67e-04 | 68 | 41 | 3 | GO:0016279 | |
| GeneOntologyMolecularFunction | transcription coactivator activity | 3.73e-04 | 303 | 41 | 5 | GO:0003713 | |
| GeneOntologyMolecularFunction | lysine N-methyltransferase activity | 3.83e-04 | 69 | 41 | 3 | GO:0016278 | |
| GeneOntologyMolecularFunction | histone methyltransferase activity | 4.17e-04 | 71 | 41 | 3 | GO:0042054 | |
| GeneOntologyMolecularFunction | transcription coregulator activity | 9.41e-04 | 562 | 41 | 6 | GO:0003712 | |
| GeneOntologyMolecularFunction | protein methyltransferase activity | 1.23e-03 | 103 | 41 | 3 | GO:0008276 | |
| GeneOntologyMolecularFunction | K63-linked polyubiquitin modification-dependent protein binding | 1.30e-03 | 26 | 41 | 2 | GO:0070530 | |
| GeneOntologyMolecularFunction | N-methyltransferase activity | 1.30e-03 | 105 | 41 | 3 | GO:0008170 | |
| GeneOntologyMolecularFunction | beta-catenin binding | 1.91e-03 | 120 | 41 | 3 | GO:0008013 | |
| GeneOntologyMolecularFunction | protein-macromolecule adaptor activity | 2.17e-03 | 1160 | 41 | 8 | GO:0030674 | |
| GeneOntologyMolecularFunction | bHLH transcription factor binding | 2.62e-03 | 37 | 41 | 2 | GO:0043425 | |
| GeneOntologyMolecularFunction | histone deacetylase binding | 3.40e-03 | 147 | 41 | 3 | GO:0042826 | |
| GeneOntologyMolecularFunction | transcription factor binding | 4.11e-03 | 753 | 41 | 6 | GO:0008134 | |
| GeneOntologyMolecularFunction | DNA-binding transcription repressor activity, RNA polymerase II-specific | 4.11e-03 | 320 | 41 | 4 | GO:0001227 | |
| GeneOntologyMolecularFunction | DNA-binding transcription repressor activity | 4.39e-03 | 326 | 41 | 4 | GO:0001217 | |
| GeneOntologyMolecularFunction | S-adenosylmethionine-dependent methyltransferase activity | 5.27e-03 | 172 | 41 | 3 | GO:0008757 | |
| GeneOntologyMolecularFunction | transcription corepressor binding | 6.54e-03 | 59 | 41 | 2 | GO:0001222 | |
| GeneOntologyMolecularFunction | pre-mRNA binding | 7.65e-03 | 64 | 41 | 2 | GO:0036002 | |
| GeneOntologyMolecularFunction | modification-dependent protein binding | 8.65e-03 | 206 | 41 | 3 | GO:0140030 | |
| GeneOntologyMolecularFunction | methyltransferase activity | 9.47e-03 | 213 | 41 | 3 | GO:0008168 | |
| GeneOntologyMolecularFunction | transferase activity, transferring one-carbon groups | 1.09e-02 | 224 | 41 | 3 | GO:0016741 | |
| GeneOntologyMolecularFunction | histone modifying activity | 1.15e-02 | 229 | 41 | 3 | GO:0140993 | |
| GeneOntologyMolecularFunction | transcription corepressor activity | 1.15e-02 | 229 | 41 | 3 | GO:0003714 | |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase II | DVL2 SOX9 LRP5 CDX1 PRDM16 FOXN4 TFAP2A GLI1 KLF5 GLI3 PRDM2 SBNO2 PROP1 MEOX1 | 3.29e-07 | 1390 | 42 | 14 | GO:0045944 |
| GeneOntologyBiologicalProcess | pattern specification process | 8.98e-07 | 526 | 42 | 9 | GO:0007389 | |
| GeneOntologyBiologicalProcess | camera-type eye morphogenesis | 1.22e-06 | 171 | 42 | 6 | GO:0048593 | |
| GeneOntologyBiologicalProcess | sensory organ development | 1.53e-06 | 730 | 42 | 10 | GO:0007423 | |
| GeneOntologyBiologicalProcess | eye morphogenesis | 3.39e-06 | 204 | 42 | 6 | GO:0048592 | |
| GeneOntologyBiologicalProcess | regionalization | 4.63e-06 | 478 | 42 | 8 | GO:0003002 | |
| GeneOntologyBiologicalProcess | bone morphogenesis | 5.15e-06 | 124 | 42 | 5 | GO:0060349 | |
| GeneOntologyBiologicalProcess | sensory organ morphogenesis | 5.41e-06 | 343 | 42 | 7 | GO:0090596 | |
| GeneOntologyBiologicalProcess | epithelial tube morphogenesis | 2.04e-05 | 421 | 42 | 7 | GO:0060562 | |
| GeneOntologyBiologicalProcess | camera-type eye development | 2.20e-05 | 426 | 42 | 7 | GO:0043010 | |
| GeneOntologyBiologicalProcess | gland morphogenesis | 2.97e-05 | 178 | 42 | 5 | GO:0022612 | |
| GeneOntologyBiologicalProcess | retina morphogenesis in camera-type eye | 3.34e-05 | 90 | 42 | 4 | GO:0060042 | |
| GeneOntologyBiologicalProcess | negative regulation of transcription by RNA polymerase II | 3.80e-05 | 1053 | 42 | 10 | GO:0000122 | |
| GeneOntologyBiologicalProcess | eye development | 4.72e-05 | 480 | 42 | 7 | GO:0001654 | |
| GeneOntologyBiologicalProcess | visual system development | 4.90e-05 | 483 | 42 | 7 | GO:0150063 | |
| GeneOntologyBiologicalProcess | sensory system development | 5.44e-05 | 491 | 42 | 7 | GO:0048880 | |
| GeneOntologyBiologicalProcess | neural retina development | 5.46e-05 | 102 | 42 | 4 | GO:0003407 | |
| GeneOntologyBiologicalProcess | dorsal/ventral pattern formation | 6.58e-05 | 107 | 42 | 4 | GO:0009953 | |
| GeneOntologyBiologicalProcess | retina development in camera-type eye | 6.68e-05 | 211 | 42 | 5 | GO:0060041 | |
| GeneOntologyBiologicalProcess | embryonic organ morphogenesis | 7.28e-05 | 351 | 42 | 6 | GO:0048562 | |
| GeneOntologyBiologicalProcess | negative regulation of DNA-templated transcription | SOX9 DRAP1 ATN1 PER2 PRDM16 TFAP2A KLF5 GLI3 PRDM2 SBNO2 PROP1 | 8.12e-05 | 1399 | 42 | 11 | GO:0045892 |
| GeneOntologyBiologicalProcess | embryonic morphogenesis | 8.16e-05 | 713 | 42 | 8 | GO:0048598 | |
| GeneOntologyBiologicalProcess | negative regulation of RNA biosynthetic process | SOX9 DRAP1 ATN1 PER2 PRDM16 TFAP2A KLF5 GLI3 PRDM2 SBNO2 PROP1 | 8.88e-05 | 1413 | 42 | 11 | GO:1902679 |
| GeneOntologyBiologicalProcess | epithelium development | 1.26e-04 | 1469 | 42 | 11 | GO:0060429 | |
| GeneOntologyBiologicalProcess | anatomical structure formation involved in morphogenesis | DVL2 SOX9 CDX1 FOXN4 TFAP2A KLF5 GLI3 CECR2 FAT3 SBNO2 MEOX1 | 1.37e-04 | 1483 | 42 | 11 | GO:0048646 |
| GeneOntologyBiologicalProcess | inner ear development | 1.57e-04 | 253 | 42 | 5 | GO:0048839 | |
| GeneOntologyBiologicalProcess | animal organ morphogenesis | 1.80e-04 | 1269 | 42 | 10 | GO:0009887 | |
| GeneOntologyBiologicalProcess | bone development | 1.91e-04 | 264 | 42 | 5 | GO:0060348 | |
| GeneOntologyBiologicalProcess | morphogenesis of an epithelium | 2.29e-04 | 619 | 42 | 7 | GO:0002009 | |
| GeneOntologyBiologicalProcess | skeletal system morphogenesis | 2.39e-04 | 277 | 42 | 5 | GO:0048705 | |
| GeneOntologyBiologicalProcess | digestive tract development | 2.55e-04 | 152 | 42 | 4 | GO:0048565 | |
| GeneOntologyBiologicalProcess | cochlea development | 2.60e-04 | 61 | 42 | 3 | GO:0090102 | |
| GeneOntologyBiologicalProcess | ventral spinal cord interneuron fate commitment | 2.64e-04 | 12 | 42 | 2 | GO:0060579 | |
| GeneOntologyBiologicalProcess | cell fate commitment involved in pattern specification | 2.64e-04 | 12 | 42 | 2 | GO:0060581 | |
| GeneOntologyBiologicalProcess | ear development | 2.72e-04 | 285 | 42 | 5 | GO:0043583 | |
| GeneOntologyBiologicalProcess | embryonic epithelial tube formation | 3.03e-04 | 159 | 42 | 4 | GO:0001838 | |
| GeneOntologyBiologicalProcess | tube morphogenesis | 3.61e-04 | 1125 | 42 | 9 | GO:0035239 | |
| GeneOntologyBiologicalProcess | ventral spinal cord interneuron differentiation | 3.63e-04 | 14 | 42 | 2 | GO:0021514 | |
| GeneOntologyBiologicalProcess | digestive system development | 3.65e-04 | 167 | 42 | 4 | GO:0055123 | |
| GeneOntologyBiologicalProcess | epithelial tube formation | 4.17e-04 | 173 | 42 | 4 | GO:0072175 | |
| GeneOntologyBiologicalProcess | embryo development | 4.90e-04 | 1437 | 42 | 10 | GO:0009790 | |
| GeneOntologyBiologicalProcess | circulatory system development | 5.04e-04 | 1442 | 42 | 10 | GO:0072359 | |
| GeneOntologyBiologicalProcess | appendage morphogenesis | 5.37e-04 | 185 | 42 | 4 | GO:0035107 | |
| GeneOntologyBiologicalProcess | limb morphogenesis | 5.37e-04 | 185 | 42 | 4 | GO:0035108 | |
| GeneOntologyBiologicalProcess | positive regulation of fat cell differentiation | 5.57e-04 | 79 | 42 | 3 | GO:0045600 | |
| GeneOntologyBiologicalProcess | tube formation | 5.59e-04 | 187 | 42 | 4 | GO:0035148 | |
| GeneOntologyBiologicalProcess | morphogenesis of embryonic epithelium | 5.94e-04 | 190 | 42 | 4 | GO:0016331 | |
| GeneOntologyBiologicalProcess | regulation of osteoblast differentiation | 6.18e-04 | 192 | 42 | 4 | GO:0045667 | |
| GeneOntologyBiologicalProcess | canonical Wnt signaling pathway | 6.42e-04 | 344 | 42 | 5 | GO:0060070 | |
| GeneOntologyBiologicalProcess | tissue morphogenesis | 7.26e-04 | 750 | 42 | 7 | GO:0048729 | |
| GeneOntologyBiologicalProcess | neural tube development | 7.47e-04 | 202 | 42 | 4 | GO:0021915 | |
| GeneOntologyBiologicalProcess | spinal cord dorsal/ventral patterning | 7.51e-04 | 20 | 42 | 2 | GO:0021513 | |
| GeneOntologyBiologicalProcess | anatomical structure regression | 7.51e-04 | 20 | 42 | 2 | GO:0060033 | |
| GeneOntologyBiologicalProcess | heart development | 7.67e-04 | 757 | 42 | 7 | GO:0007507 | |
| GeneOntologyBiologicalProcess | neuron fate commitment | 8.42e-04 | 91 | 42 | 3 | GO:0048663 | |
| GeneOntologyBiologicalProcess | embryonic organ development | 8.99e-04 | 561 | 42 | 6 | GO:0048568 | |
| GeneOntologyBiologicalProcess | ossification | 9.08e-04 | 562 | 42 | 6 | GO:0001503 | |
| GeneOntologyBiologicalProcess | spinal cord patterning | 9.11e-04 | 22 | 42 | 2 | GO:0021511 | |
| GeneOntologyBiologicalProcess | segment specification | 9.11e-04 | 22 | 42 | 2 | GO:0007379 | |
| GeneOntologyBiologicalProcess | vocalization behavior | 1.09e-03 | 24 | 42 | 2 | GO:0071625 | |
| GeneOntologyBiologicalProcess | notochord development | 1.09e-03 | 24 | 42 | 2 | GO:0030903 | |
| GeneOntologyBiologicalProcess | positive regulation of chondrocyte differentiation | 1.09e-03 | 24 | 42 | 2 | GO:0032332 | |
| GeneOntologyBiologicalProcess | limb development | 1.10e-03 | 224 | 42 | 4 | GO:0060173 | |
| GeneOntologyBiologicalProcess | appendage development | 1.10e-03 | 224 | 42 | 4 | GO:0048736 | |
| GeneOntologyBiologicalProcess | white fat cell differentiation | 1.18e-03 | 25 | 42 | 2 | GO:0050872 | |
| GeneOntologyBiologicalProcess | retina layer formation | 1.18e-03 | 25 | 42 | 2 | GO:0010842 | |
| GeneOntologyBiologicalProcess | regulation of miRNA metabolic process | 1.21e-03 | 103 | 42 | 3 | GO:2000628 | |
| GeneOntologyBiologicalProcess | roof of mouth development | 1.24e-03 | 104 | 42 | 3 | GO:0060021 | |
| GeneOntologyBiologicalProcess | tongue development | 1.38e-03 | 27 | 42 | 2 | GO:0043586 | |
| GeneOntologyBiologicalProcess | negative regulation of chondrocyte differentiation | 1.38e-03 | 27 | 42 | 2 | GO:0032331 | |
| GeneOntologyBiologicalProcess | positive regulation of stem cell differentiation | 1.38e-03 | 27 | 42 | 2 | GO:2000738 | |
| GeneOntologyBiologicalProcess | somatic stem cell population maintenance | 1.38e-03 | 108 | 42 | 3 | GO:0035019 | |
| GeneOntologyBiologicalProcess | anterior/posterior pattern specification | 1.57e-03 | 247 | 42 | 4 | GO:0009952 | |
| GeneOntologyBiologicalProcess | neural tube closure | 1.57e-03 | 113 | 42 | 3 | GO:0001843 | |
| GeneOntologyBiologicalProcess | cochlea morphogenesis | 1.59e-03 | 29 | 42 | 2 | GO:0090103 | |
| GeneOntologyBiologicalProcess | tube closure | 1.61e-03 | 114 | 42 | 3 | GO:0060606 | |
| GeneOntologyBiologicalProcess | tube development | 1.74e-03 | 1402 | 42 | 9 | GO:0035295 | |
| GeneOntologyBiologicalProcess | regulation of neuron differentiation | 1.77e-03 | 255 | 42 | 4 | GO:0045664 | |
| GeneOntologyBiologicalProcess | miRNA metabolic process | 1.82e-03 | 119 | 42 | 3 | GO:0010586 | |
| GeneOntologyBiologicalProcess | primary neural tube formation | 1.87e-03 | 120 | 42 | 3 | GO:0014020 | |
| GeneOntologyBiologicalProcess | cranial nerve morphogenesis | 1.93e-03 | 32 | 42 | 2 | GO:0021602 | |
| GeneOntologyBiologicalProcess | segmentation | 2.00e-03 | 123 | 42 | 3 | GO:0035282 | |
| GeneOntologyBiologicalProcess | chordate embryonic development | 2.17e-03 | 906 | 42 | 7 | GO:0043009 | |
| GeneOntologyBiologicalProcess | intestinal epithelial cell differentiation | 2.18e-03 | 34 | 42 | 2 | GO:0060575 | |
| GeneOntologyCellularComponent | transcription regulator complex | 2.09e-05 | 596 | 42 | 8 | GO:0005667 | |
| GeneOntologyCellularComponent | GLI-SUFU complex | 2.36e-05 | 4 | 42 | 2 | GO:1990788 | |
| GeneOntologyCellularComponent | transcription repressor complex | 2.78e-05 | 87 | 42 | 4 | GO:0017053 | |
| HumanPheno | Atrophy of the dentate nucleus | 7.02e-06 | 2 | 14 | 2 | HP:0007047 | |
| HumanPheno | Abnormal epiphyseal ossification | 7.29e-05 | 88 | 14 | 4 | HP:0010656 | |
| HumanPheno | Abnormal rib cage morphology | 7.39e-05 | 445 | 14 | 7 | HP:0001547 | |
| HumanPheno | Abnormal hand morphology | 7.75e-05 | 1082 | 14 | 10 | HP:0005922 | |
| HumanPheno | Abnormal enchondral ossification | 8.05e-05 | 180 | 14 | 5 | HP:0003336 | |
| HumanPheno | Abnormal femur morphology | 8.59e-05 | 304 | 14 | 6 | HP:0002823 | |
| HumanPheno | Abnormal hard palate morphology | 9.65e-05 | 647 | 14 | 8 | HP:0100737 | |
| HumanPheno | Abnormal lower limb bone morphology | 1.01e-04 | 866 | 14 | 9 | HP:0040069 | |
| HumanPheno | Abnormality of the thigh | 1.19e-04 | 322 | 14 | 6 | HP:0001439 | |
| HumanPheno | Abnormal rib morphology | 1.50e-04 | 336 | 14 | 6 | HP:0000772 | |
| HumanPheno | Abnormal tibia morphology | 1.57e-04 | 107 | 14 | 4 | HP:0002992 | |
| HumanPheno | Polydactyly | 1.61e-04 | 340 | 14 | 6 | HP:0010442 | |
| HumanPheno | Tibial bowing | 1.66e-04 | 41 | 14 | 3 | HP:0002982 | |
| HumanPheno | Delayed epiphyseal ossification | 1.78e-04 | 42 | 14 | 3 | HP:0002663 | |
| HumanPheno | Abnormal pelvic girdle bone morphology | 2.31e-04 | 730 | 14 | 8 | HP:0002644 | |
| HumanPheno | Hypospadias | 2.84e-04 | 377 | 14 | 6 | HP:0000047 | |
| HumanPheno | Abnormal renal morphology | 2.88e-04 | 1252 | 14 | 10 | HP:0012210 | |
| HumanPheno | Depressed nasal ridge | 3.42e-04 | 131 | 14 | 4 | HP:0000457 | |
| HumanPheno | Displacement of the urethral meatus | 3.78e-04 | 397 | 14 | 6 | HP:0100627 | |
| HumanPheno | Abnormal male urethral meatus morphology | 3.88e-04 | 399 | 14 | 6 | HP:0032076 | |
| HumanPheno | Abnormality of lower limb joint | 3.99e-04 | 1027 | 14 | 9 | HP:0100491 | |
| HumanPheno | Hand polydactyly | 4.09e-04 | 254 | 14 | 5 | HP:0001161 | |
| HumanPheno | Duplication of phalanx of hand | 4.32e-04 | 257 | 14 | 5 | HP:0009997 | |
| HumanPheno | Duplication of hand bones | 4.40e-04 | 258 | 14 | 5 | HP:0004275 | |
| HumanPheno | Duplication of bones involving the upper extremities | 4.40e-04 | 258 | 14 | 5 | HP:0009142 | |
| HumanPheno | Hydronephrosis | 4.90e-04 | 264 | 14 | 5 | HP:0000126 | |
| HumanPheno | Aplasia/hypoplasia of the extremities | 4.97e-04 | 813 | 14 | 8 | HP:0009815 | |
| HumanPheno | Abnormal morphology of bones of the lower limbs | 5.27e-04 | 422 | 14 | 6 | HP:0040066 | |
| HumanPheno | Duplication involving bones of the feet | 5.32e-04 | 147 | 14 | 4 | HP:0009136 | |
| HumanPheno | Foot polydactyly | 5.32e-04 | 147 | 14 | 4 | HP:0001829 | |
| HumanPheno | Abnormal fibula morphology | 5.68e-04 | 62 | 14 | 3 | HP:0002991 | |
| HumanPheno | Neonatal short-limb short stature | 6.26e-04 | 14 | 14 | 2 | HP:0008921 | |
| HumanPheno | Renal cyst | 6.75e-04 | 283 | 14 | 5 | HP:0000107 | |
| HumanPheno | Anencephaly | 6.83e-04 | 66 | 14 | 3 | HP:0002323 | |
| HumanPheno | Abnormal dentate nucleus morphology | 7.22e-04 | 15 | 14 | 2 | HP:0100321 | |
| HumanPheno | Abnormality of the neck | 7.25e-04 | 858 | 14 | 8 | HP:0000464 | |
| HumanPheno | Dilatation of the renal pelvis | 7.55e-04 | 290 | 14 | 5 | HP:0010946 | |
| HumanPheno | Cleft palate | 7.60e-04 | 643 | 14 | 7 | HP:0000175 | |
| HumanPheno | Short stature | WDR81 SOX9 LRP5 CLCN5 PRDM16 TFAP2A GLI1 GLI3 KIAA0586 PROP1 | 8.05e-04 | 1407 | 14 | 10 | HP:0004322 |
| HumanPheno | Preaxial polydactyly | 8.05e-04 | 164 | 14 | 4 | HP:0100258 | |
| HumanPheno | Abnormal oral frenulum morphology | 8.12e-04 | 70 | 14 | 3 | HP:0000190 | |
| HumanPheno | Abnormal hip bone morphology | 8.36e-04 | 653 | 14 | 7 | HP:0003272 | |
| HumanPheno | Abnormal renal pelvis morphology | 8.82e-04 | 300 | 14 | 5 | HP:0010944 | |
| HumanPheno | Abnormality of the urethra | 8.90e-04 | 465 | 14 | 6 | HP:0000795 | |
| HumanPheno | Abnormal hair morphology | WDR81 SOX9 SETD1B PRDM16 TFAP2A GLI1 GLI3 KIAA0586 PROP1 MEOX1 | 8.93e-04 | 1424 | 14 | 10 | HP:0001595 |
| HumanPheno | Spina bifida | 9.43e-04 | 171 | 14 | 4 | HP:0002414 | |
| HumanPheno | Brachydactyly | 9.79e-04 | 670 | 14 | 7 | HP:0001156 | |
| HumanPheno | Short digit | 9.98e-04 | 672 | 14 | 7 | HP:0011927 | |
| HumanPheno | Abnormality of the middle ear | WDR81 SOX9 LRP5 ATN1 PRDM16 TFAP2A GLI3 KIAA0586 PROP1 MEOX1 | 1.02e-03 | 1446 | 14 | 10 | HP:0000370 |
| HumanPheno | Abnormal vertebral morphology | 1.09e-03 | 483 | 14 | 6 | HP:0003468 | |
| HumanPheno | Bowing of the long bones | 1.12e-03 | 316 | 14 | 5 | HP:0006487 | |
| HumanPheno | Short limb dwarfism | 1.17e-03 | 19 | 14 | 2 | HP:0003505 | |
| HumanPheno | Accessory oral frenulum | 1.17e-03 | 19 | 14 | 2 | HP:0000191 | |
| HumanPheno | Holoprosencephaly | 1.20e-03 | 80 | 14 | 3 | HP:0001360 | |
| HumanPheno | Orofacial cleft | 1.21e-03 | 694 | 14 | 7 | HP:0000202 | |
| HumanPheno | Craniofacial cleft | 1.21e-03 | 694 | 14 | 7 | HP:5201015 | |
| HumanPheno | Cleft upper lip | 1.22e-03 | 183 | 14 | 4 | HP:0000204 | |
| HumanPheno | Anomaly of the limb diaphyses | 1.22e-03 | 322 | 14 | 5 | HP:0006504 | |
| HumanPheno | Abnormal neural tube morphology | 1.25e-03 | 324 | 14 | 5 | HP:0410043 | |
| HumanPheno | Neural tube defect | 1.25e-03 | 324 | 14 | 5 | HP:0045005 | |
| HumanPheno | Short finger | 1.27e-03 | 325 | 14 | 5 | HP:0009381 | |
| HumanPheno | Spinal dysraphism | 1.29e-03 | 186 | 14 | 4 | HP:0010301 | |
| HumanPheno | Abnormality of upper limb joint | 1.34e-03 | 705 | 14 | 7 | HP:0009810 | |
| HumanPheno | Dwarfism | 1.43e-03 | 21 | 14 | 2 | HP:0001516 | |
| HumanPheno | Sensorineural hearing impairment | 1.55e-03 | 958 | 14 | 8 | HP:0000407 | |
| HumanPheno | Abnormal diaphysis morphology | 1.62e-03 | 343 | 14 | 5 | HP:0000940 | |
| HumanPheno | Thyroid hypoplasia | 1.72e-03 | 23 | 14 | 2 | HP:0005990 | |
| HumanPheno | Abnormal femoral neck/head morphology | 1.72e-03 | 201 | 14 | 4 | HP:0003366 | |
| HumanPheno | Abnormal finger phalanx morphology | 1.76e-03 | 738 | 14 | 7 | HP:0005918 | |
| HumanPheno | Abnormal lip morphology | 1.83e-03 | 1249 | 14 | 9 | HP:0000159 | |
| HumanPheno | Ectopic anus | 1.85e-03 | 93 | 14 | 3 | HP:0004397 | |
| HumanPheno | Abnormal calvaria morphology | 1.89e-03 | 1254 | 14 | 9 | HP:0002683 | |
| HumanPheno | Aplasia/hypoplasia involving bones of the hand | 1.93e-03 | 538 | 14 | 6 | HP:0005927 | |
| HumanPheno | Renal hypoplasia/aplasia | 1.99e-03 | 359 | 14 | 5 | HP:0008678 | |
| HumanPheno | Abnormal ossification involving the femoral head and neck | 2.03e-03 | 25 | 14 | 2 | HP:0009107 | |
| HumanPheno | Aplasia/Hypoplasia of the thyroid gland | 2.03e-03 | 25 | 14 | 2 | HP:0033079 | |
| HumanPheno | Aplasia involving bones of the extremities | 2.09e-03 | 759 | 14 | 7 | HP:0009825 | |
| HumanPheno | Synostosis of joints | 2.10e-03 | 212 | 14 | 4 | HP:0100240 | |
| HumanPheno | Aplasia/hypoplasia involving bones of the extremities | 2.12e-03 | 761 | 14 | 7 | HP:0045060 | |
| HumanPheno | Delayed cranial suture closure | 2.15e-03 | 98 | 14 | 3 | HP:0000270 | |
| HumanPheno | Aplasia/Hypoplasia of fingers | 2.17e-03 | 366 | 14 | 5 | HP:0006265 | |
| HumanPheno | Thyroid dysgenesis | 2.20e-03 | 26 | 14 | 2 | HP:0008188 | |
| HumanPheno | Abnormal neck morphology | 2.21e-03 | 766 | 14 | 7 | HP:0025668 | |
| HumanPheno | Aplasia/Hypoplasia of the cerebellar vermis | 2.25e-03 | 369 | 14 | 5 | HP:0006817 | |
| HumanPheno | Cerebellar vermis hypoplasia | 2.25e-03 | 369 | 14 | 5 | HP:0001320 | |
| HumanPheno | Conductive hearing impairment | 2.36e-03 | 373 | 14 | 5 | HP:0000405 | |
| HumanPheno | Abnormal cerebellar vermis morphology | 2.39e-03 | 374 | 14 | 5 | HP:0002334 | |
| HumanPheno | Abnormal cardiac ventricle morphology | 2.46e-03 | 780 | 14 | 7 | HP:0001713 | |
| HumanPheno | Abnormal cardiac septum morphology | 2.59e-03 | 787 | 14 | 7 | HP:0001671 | |
| HumanPheno | Aplasia/hypoplasia involving bones of the upper limbs | 2.65e-03 | 572 | 14 | 6 | HP:0006496 | |
| HumanPheno | Abnormality of the calf | 2.68e-03 | 384 | 14 | 5 | HP:0002981 | |
| HumanPheno | Abnormality of the metacarpal bones | 2.74e-03 | 228 | 14 | 4 | HP:0001163 | |
| HumanPheno | Abnormal metacarpal morphology | 2.74e-03 | 228 | 14 | 4 | HP:0005916 | |
| HumanPheno | Functional abnormality of the middle ear | 2.75e-03 | 386 | 14 | 5 | HP:0011452 | |
| MousePheno | retina fold | 5.05e-07 | 25 | 37 | 4 | MP:0021107 | |
| MousePheno | abnormal bone mineralization | 1.07e-04 | 181 | 37 | 5 | MP:0002896 | |
| MousePheno | abnormal retina ganglion layer morphology | 1.11e-04 | 95 | 37 | 4 | MP:0005241 | |
| MousePheno | narrow snout | 1.42e-04 | 7 | 37 | 2 | MP:0030191 | |
| MousePheno | short maxilla | 1.46e-04 | 39 | 37 | 3 | MP:0000097 | |
| MousePheno | respiratory distress | 1.88e-04 | 204 | 37 | 5 | MP:0001954 | |
| MousePheno | abnormal xiphoid process morphology | 2.24e-04 | 45 | 37 | 3 | MP:0000159 | |
| MousePheno | absent radius | 2.43e-04 | 9 | 37 | 2 | MP:0000553 | |
| Domain | SET | 1.40e-04 | 46 | 41 | 3 | SM00317 | |
| Domain | Beach | 1.68e-04 | 9 | 41 | 2 | PF02138 | |
| Domain | - | 1.68e-04 | 9 | 41 | 2 | 1.10.1540.10 | |
| Domain | BEACH_dom | 1.68e-04 | 9 | 41 | 2 | IPR000409 | |
| Domain | Beach | 1.68e-04 | 9 | 41 | 2 | SM01026 | |
| Domain | BEACH | 1.68e-04 | 9 | 41 | 2 | PS50197 | |
| Domain | SET_dom | 1.79e-04 | 50 | 41 | 3 | IPR001214 | |
| Domain | SET | 1.79e-04 | 50 | 41 | 3 | PS50280 | |
| Domain | HTH_motif | 4.65e-04 | 69 | 41 | 3 | IPR000047 | |
| Domain | AT_hook | 5.53e-04 | 16 | 41 | 2 | PF02178 | |
| Domain | HMGI/Y_DNA-bd_CS | 2.10e-03 | 31 | 41 | 2 | IPR000637 | |
| Domain | LAM_G_DOMAIN | 3.14e-03 | 38 | 41 | 2 | PS50025 | |
| Domain | Laminin_G_2 | 3.48e-03 | 40 | 41 | 2 | PF02210 | |
| Domain | SET | 3.65e-03 | 41 | 41 | 2 | PF00856 | |
| Domain | LamG | 4.20e-03 | 44 | 41 | 2 | SM00282 | |
| Domain | Laminin_G | 7.19e-03 | 58 | 41 | 2 | IPR001791 | |
| Domain | Homeobox_CS | 7.85e-03 | 186 | 41 | 3 | IPR017970 | |
| Domain | Homeobox | 1.46e-02 | 234 | 41 | 3 | PF00046 | |
| Domain | EGF_3 | 1.47e-02 | 235 | 41 | 3 | PS50026 | |
| Domain | EGF | 1.47e-02 | 235 | 41 | 3 | SM00181 | |
| Domain | HOMEOBOX_1 | 1.49e-02 | 236 | 41 | 3 | PS00027 | |
| Domain | HOX | 1.51e-02 | 237 | 41 | 3 | SM00389 | |
| Domain | Homeobox_dom | 1.54e-02 | 239 | 41 | 3 | IPR001356 | |
| Domain | HOMEOBOX_2 | 1.54e-02 | 239 | 41 | 3 | PS50071 | |
| Domain | - | 1.59e-02 | 679 | 41 | 5 | 3.30.160.60 | |
| Domain | Homeobox_metazoa | 1.67e-02 | 90 | 41 | 2 | IPR020479 | |
| Domain | EGF-like_dom | 1.72e-02 | 249 | 41 | 3 | IPR000742 | |
| Domain | Znf_C2H2/integrase_DNA-bd | 1.73e-02 | 694 | 41 | 5 | IPR013087 | |
| Pathway | WP_WNT_SIGNALING_PATHWAY | 4.49e-06 | 110 | 32 | 5 | MM15977 | |
| Pathway | REACTOME_GLI_PROTEINS_BIND_PROMOTERS_OF_HH_RESPONSIVE_GENES_TO_PROMOTE_TRANSCRIPTION | 1.04e-04 | 7 | 32 | 2 | M27501 | |
| Pathway | WP_HEDGEHOG_SIGNALING_WP4249 | 1.23e-04 | 43 | 32 | 3 | M39706 | |
| Pathway | PID_HEDGEHOG_GLI_PATHWAY | 1.71e-04 | 48 | 32 | 3 | M219 | |
| Pathway | WP_WNT_SIGNALING_WP363 | 2.05e-04 | 51 | 32 | 3 | M39721 | |
| Pathway | KEGG_BASAL_CELL_CARCINOMA | 2.57e-04 | 55 | 32 | 3 | M17807 | |
| Pathway | REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS | 2.71e-04 | 11 | 32 | 2 | MM15510 | |
| Pathway | REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS | 3.25e-04 | 12 | 32 | 2 | M27765 | |
| Pathway | REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4 | 4.47e-04 | 14 | 32 | 2 | MM15161 | |
| Pathway | KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY | 4.47e-04 | 14 | 32 | 2 | M47414 | |
| Pathway | REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4 | 5.15e-04 | 15 | 32 | 2 | M27413 | |
| Pathway | BIOCARTA_SHH_PATHWAY | 5.15e-04 | 15 | 32 | 2 | MM1498 | |
| Pathway | WP_HEDGEHOG_SIGNALING_WP47 | 5.87e-04 | 16 | 32 | 2 | M39675 | |
| Pathway | BIOCARTA_SHH_PATHWAY | 5.87e-04 | 16 | 32 | 2 | M11792 | |
| Pathway | REACTOME_HEDGEHOG_ON_STATE | 8.04e-04 | 81 | 32 | 3 | MM15225 | |
| Pathway | REACTOME_HEDGEHOG_ON_STATE | 9.57e-04 | 86 | 32 | 3 | M27497 | |
| Pathway | WP_HEDGEHOG_SIGNALING_PATHWAY | 1.12e-03 | 22 | 32 | 2 | MM15924 | |
| Pathway | WP_NEURAL_CREST_DIFFERENTIATION | 1.36e-03 | 97 | 32 | 3 | MM15926 | |
| Pathway | WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER | 1.40e-03 | 98 | 32 | 3 | M39731 | |
| Pathway | WP_NEURAL_CREST_DIFFERENTIATION | 1.52e-03 | 101 | 32 | 3 | M39448 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS | 1.57e-03 | 26 | 32 | 2 | MM15502 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY | 1.95e-03 | 29 | 32 | 2 | M47372 | |
| Pathway | KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY | 1.95e-03 | 29 | 32 | 2 | M47377 | |
| Pathway | REACTOME_SIGNALING_BY_WNT | 2.00e-03 | 239 | 32 | 4 | MM14756 | |
| Pathway | REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE | 2.23e-03 | 31 | 32 | 2 | M27400 | |
| Pathway | WP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1 | 2.23e-03 | 31 | 32 | 2 | M39522 | |
| Pathway | REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE | 2.23e-03 | 31 | 32 | 2 | MM15154 | |
| Pathway | PID_WNT_NONCANONICAL_PATHWAY | 2.37e-03 | 32 | 32 | 2 | M23 | |
| Pathway | WP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_STAGE_2_OF_3 | 2.37e-03 | 32 | 32 | 2 | M40041 | |
| Pathway | WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES | 2.38e-03 | 118 | 32 | 3 | M39852 | |
| Pathway | WP_WNT_SIGNALING_IN_KIDNEY_DISEASE | 3.00e-03 | 36 | 32 | 2 | M39699 | |
| Pathway | KEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY | 3.16e-03 | 37 | 32 | 2 | M47411 | |
| Pathway | WP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION | 3.26e-03 | 132 | 32 | 3 | M48110 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS | 3.33e-03 | 38 | 32 | 2 | M27757 | |
| Pathway | REACTOME_SIGNALING_BY_HEDGEHOG | 3.62e-03 | 137 | 32 | 3 | MM15182 | |
| Pubmed | 1.30e-09 | 13 | 42 | 4 | 36220081 | ||
| Pubmed | Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development. | 7.03e-09 | 19 | 42 | 4 | 25848030 | |
| Pubmed | A census of human transcription factors: function, expression and evolution. | SOX9 CDX1 DRAP1 FOXN4 TFAP2A GLI1 KLF5 GLI3 PRDM2 PROP1 MEOX1 | 7.39e-09 | 908 | 42 | 11 | 19274049 |
| Pubmed | 9.51e-09 | 709 | 42 | 10 | 22988430 | ||
| Pubmed | 3.16e-08 | 27 | 42 | 4 | 19168680 | ||
| Pubmed | 4.92e-08 | 30 | 42 | 4 | 16368932 | ||
| Pubmed | 4.92e-08 | 30 | 42 | 4 | 24073291 | ||
| Pubmed | 8.30e-08 | 34 | 42 | 4 | 26288816 | ||
| Pubmed | 1.18e-07 | 37 | 42 | 4 | 23266329 | ||
| Pubmed | 1.37e-07 | 9 | 42 | 3 | 21356198 | ||
| Pubmed | Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. | 1.37e-07 | 9 | 42 | 3 | 25083987 | |
| Pubmed | Neogenin regulates Sonic Hedgehog pathway activity during digit patterning. | 1.95e-07 | 10 | 42 | 3 | 22275192 | |
| Pubmed | Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. | 1.95e-07 | 10 | 42 | 3 | 14602680 | |
| Pubmed | Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice. | 1.95e-07 | 10 | 42 | 3 | 35977544 | |
| Pubmed | 1.95e-07 | 10 | 42 | 3 | 16791844 | ||
| Pubmed | Sonic hedgehog is required for cardiac outflow tract and neural crest cell development. | 2.68e-07 | 11 | 42 | 3 | 15936751 | |
| Pubmed | Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. | 3.58e-07 | 12 | 42 | 3 | 24990743 | |
| Pubmed | Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. | 3.58e-07 | 12 | 42 | 3 | 23994639 | |
| Pubmed | 4.64e-07 | 13 | 42 | 3 | 34887903 | ||
| Pubmed | Temporomandibular joint formation and condyle growth require Indian hedgehog signaling. | 4.64e-07 | 13 | 42 | 3 | 17191253 | |
| Pubmed | A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis. | 5.15e-07 | 53 | 42 | 4 | 38466355 | |
| Pubmed | Genetic interaction between Gli3 and Ezh2 during limb pattern formation. | 5.91e-07 | 14 | 42 | 3 | 29729398 | |
| Pubmed | 5.91e-07 | 14 | 42 | 3 | 23313125 | ||
| Pubmed | Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. | 9.07e-07 | 16 | 42 | 3 | 17222543 | |
| Pubmed | Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner. | 9.07e-07 | 16 | 42 | 3 | 34346313 | |
| Pubmed | 1.10e-06 | 17 | 42 | 3 | 18330926 | ||
| Pubmed | 1.10e-06 | 17 | 42 | 3 | 24726282 | ||
| Pubmed | 1.32e-06 | 18 | 42 | 3 | 24424161 | ||
| Pubmed | 1.32e-06 | 18 | 42 | 3 | 27352137 | ||
| Pubmed | 1.32e-06 | 18 | 42 | 3 | 32901292 | ||
| Pubmed | 1.32e-06 | 18 | 42 | 3 | 20386744 | ||
| Pubmed | 1.32e-06 | 18 | 42 | 3 | 14645126 | ||
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 18559511 | ||
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 12351188 | ||
| Pubmed | A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome. | 1.42e-06 | 2 | 42 | 2 | 21921029 | |
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 16595674 | ||
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 25103784 | ||
| Pubmed | Palmar and plantar pads and flexion creases of genetic polydactyly mice (Pdn). | 1.42e-06 | 2 | 42 | 2 | 9918099 | |
| Pubmed | Gli3 is a Key Factor in the Schwann Cells from Both Intact and Injured Peripheral Nerves. | 1.42e-06 | 2 | 42 | 2 | 32114096 | |
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 10693759 | ||
| Pubmed | gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development. | 1.42e-06 | 2 | 42 | 2 | 8364225 | |
| Pubmed | Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis. | 1.42e-06 | 2 | 42 | 2 | 31270323 | |
| Pubmed | 1.57e-06 | 19 | 42 | 3 | 22698544 | ||
| Pubmed | Cooperative activity of noggin and gremlin 1 in axial skeleton development. | 1.57e-06 | 19 | 42 | 3 | 21303853 | |
| Pubmed | FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue. | 1.57e-06 | 19 | 42 | 3 | 34348145 | |
| Pubmed | Fuz regulates craniofacial development through tissue specific responses to signaling factors. | 1.84e-06 | 20 | 42 | 3 | 21935430 | |
| Pubmed | 1.84e-06 | 20 | 42 | 3 | 21045211 | ||
| Pubmed | 1.84e-06 | 20 | 42 | 3 | 20637749 | ||
| Pubmed | FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds. | 2.15e-06 | 21 | 42 | 3 | 19386269 | |
| Pubmed | HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly. | 2.15e-06 | 21 | 42 | 3 | 34928956 | |
| Pubmed | Temporomandibular joint formation requires two distinct hedgehog-dependent steps. | 2.15e-06 | 21 | 42 | 3 | 19815519 | |
| Pubmed | Onecut1 is essential for horizontal cell genesis and retinal integrity. | 2.15e-06 | 21 | 42 | 3 | 23926259 | |
| Pubmed | 2.48e-06 | 22 | 42 | 3 | 28432216 | ||
| Pubmed | 2.85e-06 | 23 | 42 | 3 | 16672333 | ||
| Pubmed | Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. | 2.85e-06 | 23 | 42 | 3 | 25966682 | |
| Pubmed | 2.85e-06 | 23 | 42 | 3 | 29222391 | ||
| Pubmed | Generation of mice with functional inactivation of talpid3, a gene first identified in chicken. | 2.85e-06 | 23 | 42 | 3 | 21750036 | |
| Pubmed | The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. | 3.26e-06 | 24 | 42 | 3 | 31896583 | |
| Pubmed | 3.26e-06 | 24 | 42 | 3 | 39012257 | ||
| Pubmed | Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. | 3.26e-06 | 24 | 42 | 3 | 21803035 | |
| Pubmed | 3.70e-06 | 25 | 42 | 3 | 27046536 | ||
| Pubmed | Impact of cytosine methylation on DNA binding specificities of human transcription factors. | 3.70e-06 | 544 | 42 | 7 | 28473536 | |
| Pubmed | The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. | 4.18e-06 | 26 | 42 | 3 | 27697904 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 30685841 | ||
| Pubmed | Rab23 regulates differentiation of ATDC5 chondroprogenitor cells. | 4.27e-06 | 3 | 42 | 2 | 18218620 | |
| Pubmed | Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation. | 4.27e-06 | 3 | 42 | 2 | 24311597 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 26010061 | ||
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 23112162 | ||
| Pubmed | Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. | 4.27e-06 | 3 | 42 | 2 | 10075717 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 8387379 | ||
| Pubmed | VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context. | 4.27e-06 | 3 | 42 | 2 | 29199069 | |
| Pubmed | Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling. | 4.27e-06 | 3 | 42 | 2 | 16571352 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 29722127 | ||
| Pubmed | Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development. | 4.27e-06 | 3 | 42 | 2 | 22178118 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 5806166 | ||
| Pubmed | Methylation of PRDM2, PRDM5 and PRDM16 genes in lung cancer cells. | 4.27e-06 | 3 | 42 | 2 | 24966940 | |
| Pubmed | The amino-terminal domain of glutamate receptor delta2 triggers presynaptic differentiation. | 4.27e-06 | 3 | 42 | 2 | 19000899 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 28965847 | ||
| Pubmed | Gli family members are differentially expressed during the mitotic phase of spermatogenesis. | 4.27e-06 | 3 | 42 | 2 | 9178901 | |
| Pubmed | Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. | 4.27e-06 | 3 | 42 | 2 | 8378770 | |
| Pubmed | 5.25e-06 | 28 | 42 | 3 | 26884322 | ||
| Pubmed | 5.25e-06 | 28 | 42 | 3 | 35112129 | ||
| Pubmed | 5.85e-06 | 29 | 42 | 3 | 19474320 | ||
| Pubmed | 5.85e-06 | 29 | 42 | 3 | 26959361 | ||
| Pubmed | 6.44e-06 | 383 | 42 | 6 | 19453261 | ||
| Pubmed | 6.50e-06 | 30 | 42 | 3 | 23482494 | ||
| Pubmed | 7.93e-06 | 32 | 42 | 3 | 19286674 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 9027508 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 8995757 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 22281533 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 9006072 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 27793025 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 15793308 | ||
| Pubmed | Wnt signaling mediates pathological vascular growth in proliferative retinopathy. | 8.53e-06 | 4 | 42 | 2 | 21969016 | |
| Pubmed | Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice. | 8.53e-06 | 4 | 42 | 2 | 18579683 | |
| Pubmed | Expression profile of Gli family members and Shh in normal and mutant mouse limb development. | 8.53e-06 | 4 | 42 | 2 | 9438426 | |
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 25632159 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 8150204 | ||
| Pubmed | CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. | 8.53e-06 | 4 | 42 | 2 | 35504891 | |
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 9858544 | ||
| Interaction | WWP1 interactions | 1.34e-05 | 260 | 41 | 6 | int:WWP1 | |
| GeneFamily | Zinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family | 2.15e-05 | 34 | 29 | 3 | 487 | |
| GeneFamily | WD repeat domain containing|BEACH domain containing | 8.88e-05 | 9 | 29 | 2 | 1230 | |
| GeneFamily | Zinc fingers C2H2-type|PR/SET domain family | 3.33e-04 | 17 | 29 | 2 | 1197 | |
| GeneFamily | HOXL subclass homeoboxes | 3.13e-03 | 52 | 29 | 2 | 518 | |
| GeneFamily | WD repeat domain containing | 8.32e-03 | 262 | 29 | 3 | 362 | |
| Coexpression | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_UP | 1.66e-05 | 200 | 42 | 5 | M6623 | |
| CoexpressionAtlas | FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500 | 3.48e-05 | 496 | 40 | 7 | Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500 | |
| CoexpressionAtlas | FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000 | 7.20e-05 | 986 | 40 | 9 | Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000 | |
| ToppCell | facs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.01e-07 | 173 | 42 | 5 | e944ea3a0a368f856efacbda4600605cf751dd9c | |
| ToppCell | facs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.01e-07 | 173 | 42 | 5 | 85fa5918e9c1f6bb4757e3350cfc71ee75c55640 | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.83e-07 | 187 | 42 | 5 | e04a84989d624378141042768383b9c846901f2d | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.83e-07 | 187 | 42 | 5 | 24cc03c748e15f7ef0e6509ca5a6ca583fb9c573 | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 8.83e-07 | 187 | 42 | 5 | 2f153b203fe79f206319603cf94d3a03ab49a05d | |
| ToppCell | 3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.17e-06 | 198 | 42 | 5 | c66097ae9ba0b50561083c423565665958ef0bb8 | |
| ToppCell | primary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.30e-05 | 153 | 42 | 4 | 95b28c5bd10ffb74c0993ebd565038b9818e4bd2 | |
| ToppCell | primary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.30e-05 | 153 | 42 | 4 | b09f8def40a1ea56722f3398f61a036667b61cd9 | |
| ToppCell | primary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.30e-05 | 153 | 42 | 4 | 3ab9d55b3db51715c1d61eca142384195ce4b54f | |
| ToppCell | frontal_cortex-Non-neuronal-astrocyte|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.44e-05 | 157 | 42 | 4 | 803af734d7f775d294391e2b84e472a732e18cef | |
| ToppCell | frontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.44e-05 | 157 | 42 | 4 | 9aa5304a9704da6dd4eda7d6940494b00e38b2e8 | |
| ToppCell | frontal_cortex-Non-neuronal-astrocyte-Astro|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype | 1.44e-05 | 157 | 42 | 4 | 0551442ae14685d8fe5729e3960c6324b1e05e4d | |
| ToppCell | TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9 | 1.71e-05 | 164 | 42 | 4 | 81c41e1b5535b7969bcf6fa2456f828e8e8e2ff7 | |
| ToppCell | TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9 | 1.84e-05 | 167 | 42 | 4 | d2230c894ccf9dbba9196e079ae81f384d43da63 | |
| ToppCell | droplet-Liver-LIVER-NPC-1m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.97e-05 | 170 | 42 | 4 | bcbe5c44ef708c5f01dc7dd9aec7b436e1a62d56 | |
| ToppCell | (7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1) | 2.68e-05 | 184 | 42 | 4 | b89871a3e36fde6daa68daf116f8c8d587554c0f | |
| ToppCell | 343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells) | 2.74e-05 | 185 | 42 | 4 | 02cbf492bc40abebaa93a3a208888afae72fbe06 | |
| ToppCell | 343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells) | 2.74e-05 | 185 | 42 | 4 | 1b8e3ddb91797f84e4b15d2457b0c008e5be50db | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.23e-05 | 193 | 42 | 4 | 461919ab422bc9d1fcff7a3a4757c75239041d7e | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.23e-05 | 193 | 42 | 4 | 0dd810ad900d3e586551622b2c1de39d76fd6a7f | |
| ToppCell | BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k) | 3.43e-05 | 196 | 42 | 4 | 808c0a7d1889a8f3508ed9790c6dc7ec16bbc840 | |
| ToppCell | BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k) | 3.43e-05 | 196 | 42 | 4 | b246e482f012dd9782b49c2a953acedfa3c1139d | |
| ToppCell | Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 3.72e-05 | 200 | 42 | 4 | 41705bbba40eb5ddca0b223191aac1bce00163b8 | |
| ToppCell | Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09) | 3.72e-05 | 200 | 42 | 4 | cc8df398532c9324fd3e171000b1ea5c208cd691 | |
| ToppCell | Parenchyma_COVID-19-Epithelial-TX-Basal_3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type | 3.72e-05 | 200 | 42 | 4 | 53e04399d0308b40ae99fbfaa4ff62bf061822d8 | |
| ToppCell | Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32 | 6.36e-05 | 82 | 42 | 3 | 89aff8676f98e062d0e69b38c7184e51aa1a915e | |
| ToppCell | Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32 | 6.36e-05 | 82 | 42 | 3 | 6875a10abf1221b3dfd954c319b5e8e12fac1ff2 | |
| ToppCell | Substantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Igfbp2)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32 | 6.36e-05 | 82 | 42 | 3 | 259bb4ae0373d8352cb1c3bff08f66b89a298440 | |
| ToppCell | PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.74e-04 | 115 | 42 | 3 | 36cbb8666b33199b7552879922789bc227525b7b | |
| ToppCell | PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09) | 1.74e-04 | 115 | 42 | 3 | 6f92e45cbe9924ade10cb8a41884b0202070ab31 | |
| ToppCell | Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32 | 2.02e-04 | 121 | 42 | 3 | 8334a6b2ced1d6a4808458d6d4232d1b688ba28a | |
| ToppCell | Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--|Hippocampus / BrainAtlas - Mouse McCarroll V32 | 2.02e-04 | 121 | 42 | 3 | 4b33eeed7b70da120133b14d42c104d2461d52dc | |
| ToppCell | Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32 | 2.02e-04 | 121 | 42 | 3 | a33e4ae0b0efb702db1b646ac0486e3b6ce48457 | |
| ToppCell | VE-CD4-CD8_2|VE / Condition, Cell_class and T cell subcluster | 2.07e-04 | 122 | 42 | 3 | 6745035feaf807b6a6b9537ac9d5ee0e000196eb | |
| ToppCell | Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32 | 2.38e-04 | 128 | 42 | 3 | 7e3f5cea91af005f08d8e9340fb8630bf1c887c3 | |
| ToppCell | Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Striatum / BrainAtlas - Mouse McCarroll V32 | 2.38e-04 | 128 | 42 | 3 | a876303c852db2af9418d1a1711d7c950805018a | |
| ToppCell | Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32 | 2.38e-04 | 128 | 42 | 3 | 388062f840fd04cb8087f27a9a78e7a192920e3e | |
| ToppCell | metastatic_Brain-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass | 3.23e-04 | 142 | 42 | 3 | 1eecbec805a873fa3539df0574670cf73c18c7b1 | |
| ToppCell | TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9 | 4.09e-04 | 154 | 42 | 3 | 4e9203c220a44c70cd7979796a0b461991422257 | |
| ToppCell | facs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.17e-04 | 155 | 42 | 3 | 72a19a9ecfd13f6769c4b447d3ce01a855ec6ec7 | |
| ToppCell | Control-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 4.33e-04 | 157 | 42 | 3 | 4766f7d545bf2d775390589460677519cb92f4d5 | |
| ToppCell | AT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id | 4.41e-04 | 158 | 42 | 3 | 3bc51cfd37b289cc3e866b54ce55a298e5eff690 | |
| ToppCell | renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 4.41e-04 | 158 | 42 | 3 | 7960337d87afecf2692ab65e5991f052ceddfacc | |
| ToppCell | wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung | 4.41e-04 | 158 | 42 | 3 | adad97e6cf479d42791c5ba9cbc5f15f469322bf | |
| ToppCell | tumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass | 4.49e-04 | 159 | 42 | 3 | b3c52908cd24bbf851fac69db3850fc7f53c2092 | |
| ToppCell | normal_Pleural_Fluid-B_lymphocytes-Undetermined|normal_Pleural_Fluid / Location, Cell class and cell subclass | 4.58e-04 | 160 | 42 | 3 | 5744cd30709f38e84f7ec8893dc19d7a288b465a | |
| ToppCell | cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 4.58e-04 | 160 | 42 | 3 | 9049707a4487f2337a17976ceb5fbd8815ab9e1d | |
| ToppCell | COVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass | 4.58e-04 | 160 | 42 | 3 | 61f4cb4eb4313d8318aadbb99595a6cb7fd919f7 | |
| ToppCell | facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.58e-04 | 160 | 42 | 3 | c381ec6be8cf887861cc18f831a20db42f953fe1 | |
| ToppCell | cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 4.58e-04 | 160 | 42 | 3 | f2cfec54cf48a655f473b830be7d141c54b521ff | |
| ToppCell | COVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass | 4.58e-04 | 160 | 42 | 3 | 34b4f710cfcb6ec370b8b074f3cbfe272f392cec | |
| ToppCell | facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 4.58e-04 | 160 | 42 | 3 | 25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585 | |
| ToppCell | cellseq2-Epithelial-Epithelial_Neuro-Secretory|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 4.58e-04 | 160 | 42 | 3 | 0eb50b3c494e1b65d40104b3b5411b57bb72b959 | |
| ToppCell | 368C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells) | 4.66e-04 | 161 | 42 | 3 | 1011094c54381d52566e24c92f89f2efc2aa3eea | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 4.66e-04 | 161 | 42 | 3 | 4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb | |
| ToppCell | 3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 4.92e-04 | 164 | 42 | 3 | ea02ca343b2b28e437304de889e2ae1e315a1197 | |
| ToppCell | Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor | 5.09e-04 | 166 | 42 | 3 | c20479fe7a4306320d7f26e78bf956225f00f35a | |
| ToppCell | LPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 5.09e-04 | 166 | 42 | 3 | 1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d | |
| ToppCell | LPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 5.09e-04 | 166 | 42 | 3 | 9628522e7af8f8edca733588a364ab2454ac5ca5 | |
| ToppCell | PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k) | 5.09e-04 | 166 | 42 | 3 | c8fd241088de27c6e741a5dfee3cd770183b6bcb | |
| ToppCell | facs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.18e-04 | 167 | 42 | 3 | 2184c2760b6142e62124a2454a552723e20d4f61 | |
| ToppCell | mild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2) | 5.27e-04 | 168 | 42 | 3 | 968405ea56f7d001ef83ff9274610923c3b2d55d | |
| ToppCell | Tuft-tuft-1|World / Class top | 5.27e-04 | 168 | 42 | 3 | 8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-basal_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 5.27e-04 | 168 | 42 | 3 | 6521bead9789d626b86cbd08692c621c5a5aef33 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-basal_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 5.37e-04 | 169 | 42 | 3 | c3ee781735a9288ce1822b230d39bb91c1415589 | |
| ToppCell | PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 5.37e-04 | 169 | 42 | 3 | 8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940 | |
| ToppCell | (7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1) | 5.46e-04 | 170 | 42 | 3 | 4ab495b38a071fa8207331df2ce0d78a2dcd034e | |
| ToppCell | facs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.46e-04 | 170 | 42 | 3 | 37c647f67505aa1ff12a198df1eeddd9f406fe15 | |
| ToppCell | facs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.46e-04 | 170 | 42 | 3 | b180ec9a1b79025a180c8559c27c31272410dea8 | |
| ToppCell | wk_08-11-Epithelial-Proximal_epithelial-basal_late|wk_08-11 / Celltypes from embryonic and fetal-stage human lung | 5.46e-04 | 170 | 42 | 3 | 83320d37f0fc74e492cfe3de18f5c499eaa9fd3e | |
| ToppCell | facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.55e-04 | 171 | 42 | 3 | 99176a932569fa1c7e1c01009684f5a65244b96e | |
| ToppCell | 10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 5.55e-04 | 171 | 42 | 3 | c2b7bbabc8f9afa8a1157b567d5f962d4b242919 | |
| ToppCell | droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.65e-04 | 172 | 42 | 3 | c0bda7153e02bee7d0326138cc684151c404c2a1 | |
| ToppCell | Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 5.65e-04 | 172 | 42 | 3 | 55fba5ce0ead1114e1a76f67ad68432c6bac90e5 | |
| ToppCell | 11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class | 5.65e-04 | 172 | 42 | 3 | 9d4d92e2d16dfc8a394f2641653bb97de20a2530 | |
| ToppCell | normal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass | 5.65e-04 | 172 | 42 | 3 | 200b2e63313b110b8ca59ee5b72c02cc8ed907cd | |
| ToppCell | ASK428-Immune-B_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq | 5.84e-04 | 174 | 42 | 3 | b5a7a612a515736cf3489afd0f6ad2054d54526f | |
| ToppCell | 3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.84e-04 | 174 | 42 | 3 | ca067e8ec55bbc3deafc09f08bc13af08364d165 | |
| ToppCell | wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung | 5.84e-04 | 174 | 42 | 3 | 9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c | |
| ToppCell | droplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.94e-04 | 175 | 42 | 3 | c1c722db42da9b8a2a46e516ddb83d9be5e2e504 | |
| ToppCell | ASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq | 5.94e-04 | 175 | 42 | 3 | e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c | |
| ToppCell | P15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase | 5.94e-04 | 175 | 42 | 3 | 085cceb1fc2c4ae2f27e85cea5702defecc2cf44 | |
| ToppCell | 3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 5.94e-04 | 175 | 42 | 3 | 0431897d7fcc9cefb516cd36987cf18b7f19a26a | |
| ToppCell | 5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.04e-04 | 176 | 42 | 3 | e7502a345b2da83a9a60f50cf78f1aef385c99df | |
| ToppCell | COVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type | 6.14e-04 | 177 | 42 | 3 | f54691e5558091c1734ab15153a10bff15ed171e | |
| ToppCell | Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 6.24e-04 | 178 | 42 | 3 | 4813d6509738f088c12ebf395b70d496af04649a | |
| ToppCell | droplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.24e-04 | 178 | 42 | 3 | 408e41c853f608965cef9111fb87fdc311cdc7a8 | |
| ToppCell | 3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.34e-04 | 179 | 42 | 3 | 6405010e8136a4d9bab356f628e36e3194911112 | |
| ToppCell | droplet-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.34e-04 | 179 | 42 | 3 | dfd9d29281510d32f1a2e8336d2e58ef496cfd1d | |
| ToppCell | 3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.45e-04 | 180 | 42 | 3 | 8d9be9cfdf98e5888654a28ab12e5e89f201af00 | |
| ToppCell | normal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass | 6.55e-04 | 181 | 42 | 3 | cc7ae1221a28bc404138a7efee0ad08a19cc3d86 | |
| ToppCell | 10x5'v1-week_17-19-Lymphocytic_T-T_NK-CD8_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5' | 6.66e-04 | 182 | 42 | 3 | 98c26ad34e01c4b8997d26d5d28a9935491295fa | |
| ToppCell | facs-Skin-Anagen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.66e-04 | 182 | 42 | 3 | 22d6f4790950508e8aa27e02a8133af5f53f13c8 | |
| ToppCell | Control-Epithelial-Basal|Control / Disease state, Lineage and Cell class | 6.66e-04 | 182 | 42 | 3 | caddd0a52f0234ea6a916186ffaf2454cdcd80ee | |
| ToppCell | facs|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.66e-04 | 182 | 42 | 3 | 08f775135b451be709f5fc8e1cbcf63425794a2e | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 6.66e-04 | 182 | 42 | 3 | 5f513bbb7125956eb528e3120de3fd776770a7c3 | |
| ToppCell | renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 6.66e-04 | 182 | 42 | 3 | 041bc819e6cf2618bf86bce8dfe2df673f392ba3 | |
| ToppCell | 3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.76e-04 | 183 | 42 | 3 | 0d21befacefc6c597e7b501ed41b7fe9385a78df | |
| ToppCell | 3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 6.76e-04 | 183 | 42 | 3 | 263937906ddabc798bbe60f0da28ba859a5c72e2 | |
| ToppCell | Frontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32 | 6.87e-04 | 184 | 42 | 3 | 235890e8b424f4386b6ea52d173d20a00898df73 | |
| Computational | Genes in the cancer module 123. | 4.22e-05 | 247 | 29 | 6 | MODULE_123 | |
| Computational | Developmental processes. | 2.20e-04 | 333 | 29 | 6 | MODULE_220 | |
| Drug | Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT_HG-U133A | 1.93e-05 | 184 | 41 | 5 | 4610_DN | |
| Drug | Galanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; PC3; HT_HG-U133A | 2.43e-05 | 193 | 41 | 5 | 4186_DN | |
| Drug | (d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; HL60; HT_HG-U133A | 2.55e-05 | 195 | 41 | 5 | 2163_DN | |
| Drug | Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A | 2.55e-05 | 195 | 41 | 5 | 1688_DN | |
| Drug | Ethosuximide [77-67-8]; Up 200; 28.4uM; HL60; HG-U133A | 2.81e-05 | 199 | 41 | 5 | 1433_UP | |
| Disease | primary bacterial infectious disease (implicated_via_orthology) | 7.08e-05 | 9 | 42 | 2 | DOID:0050338 (implicated_via_orthology) | |
| Disease | advanced glycosylation end product-specific receptor, soluble measurement | 1.53e-04 | 13 | 42 | 2 | EFO_0020131 | |
| Disease | pre-malignant neoplasm (biomarker_via_orthology) | 2.65e-04 | 17 | 42 | 2 | DOID:0060071 (biomarker_via_orthology) | |
| Disease | Polydactyly | 6.23e-04 | 117 | 42 | 3 | C0152427 | |
| Disease | Exencephaly | 7.30e-04 | 28 | 42 | 2 | C0266453 | |
| Disease | Neurenteric Cyst | 7.30e-04 | 28 | 42 | 2 | C0027806 | |
| Disease | Iniencephaly | 7.30e-04 | 28 | 42 | 2 | C0152234 | |
| Disease | Acrania | 7.30e-04 | 28 | 42 | 2 | C0702169 | |
| Disease | Tethered Cord Syndrome | 7.30e-04 | 28 | 42 | 2 | C0080218 | |
| Disease | Diastematomyelia | 7.30e-04 | 28 | 42 | 2 | C0011999 | |
| Disease | Spinal Cord Myelodysplasia | 7.30e-04 | 28 | 42 | 2 | C0344479 | |
| Disease | Craniorachischisis | 7.84e-04 | 29 | 42 | 2 | C0152426 | |
| Disease | caudate nucleus volume | 8.39e-04 | 30 | 42 | 2 | EFO_0004830 | |
| Disease | Neural Tube Defects | 8.39e-04 | 30 | 42 | 2 | C0027794 | |
| Disease | Bladder Neoplasm | 1.05e-03 | 140 | 42 | 3 | C0005695 | |
| Disease | Malignant neoplasm of urinary bladder | 1.07e-03 | 141 | 42 | 3 | C0005684 | |
| Disease | hippocampal CA3 volume | 1.21e-03 | 36 | 42 | 2 | EFO_0009395 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| PPAPPQYPDFSSYSH | 36 | P47902 | |
| ASDPPPPYSDFHPNN | 301 | Q15018 | |
| ASQALPSYPHSFPPP | 401 | P54259 | |
| SHTPNADFQPPYFPP | 46 | P05549 | |
| YPPPPVFTNHSTFLQ | 466 | Q6P1W5 | |
| GPPYTPQRPASHFQP | 1366 | Q9BXF3 | |
| PLLPTFSYQYPAPHP | 546 | O14641 | |
| FIATYQAFPPVPNPP | 81 | P32121 | |
| SAHFQSPPTPFLPFA | 166 | Q14919 | |
| PHYPPTPFSFHQKPD | 36 | P50221 | |
| SESPFSPPHPYINPY | 186 | P10071 | |
| TERSYFHLFPPPPSP | 1596 | O75197 | |
| SAPPAPHANPSNPFY | 501 | Q96Q04 | |
| PAHQAPTYPGPSTYP | 3076 | Q9UPA5 | |
| PQAFFPSQPQFPSHP | 921 | O15055 | |
| VATRSPFVPPPPTFY | 1436 | Q9P2S2 | |
| PLFSHYPQPSPPQYL | 846 | P08151 | |
| DFVPPVPPPSYFATF | 141 | Q15884 | |
| APPPTAHPFAGYFTF | 376 | A8MY62 | |
| YFTEHSPPLPPYTPP | 731 | P51795 | |
| FHPSQYLPPHPFPNE | 4456 | Q8TDW7 | |
| FPYAAFPTPSHPRLQ | 691 | Q6UWL6 | |
| PNFEPPQYPYIPAHI | 151 | O43809 | |
| PSFKPPPFQYHHRNP | 1296 | Q13029 | |
| PPHLYSPATQPQFPL | 136 | Q96NZ1 | |
| PYFNQPDSTHPSPPS | 6 | Q8N808 | |
| AYHSPPPSQCPSPFS | 291 | Q8N5C8 | |
| STTPPHPYQQGPPSY | 326 | Q8N5C8 | |
| RFHPSAYPPCPHPSF | 326 | P58872 | |
| PVFYSQHSFFPPPDE | 666 | Q9HAZ2 | |
| PFQFLPNFPHSLYPF | 726 | Q9HAZ2 | |
| YSPPAEAFPPPPHFS | 1261 | Q9Y2G9 | |
| AFSPYQTPVAHFPPP | 396 | Q9UPS6 | |
| YGATHSTFQPPRPPP | 541 | Q9P2U7 | |
| VSHTPAPPASFPVPY | 951 | Q9NQW1 | |
| SPFNLPHYSPSYPPI | 421 | P48436 | |
| YQHPASFGSRPFPVP | 151 | Q9ULL5 | |
| SPPPPQGQPYFDRFS | 11 | P35612 | |
| AFGPPSSFQPFPAVP | 66 | Q96RK1 | |
| PVSLPGHPQPFFYSL | 2836 | Q6ZS81 | |
| SYAAPPPPVTCFPHP | 156 | O75360 | |
| FPVPSSAYPQGVHPA | 1541 | A7E2V4 | |
| PFSSVVPFPPYFPAL | 866 | Q562E7 | |
| YNGPPFPPVASTFQP | 891 | Q9BVV6 | |
| QFLPQQATYFPPSPP | 291 | Q13887 |