Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ADAM8 ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	8.36e-18	190	190	22	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ADAM8 ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	5.34e-17	207	190	22	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ADAM8 ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	8.92e-17	212	190	22	GO:0017171
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-6 HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ERVK-7 ERVK-10 ADAM8 ADAM28 ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 USP10 GZMH ERVK-8 PSMD14	1.08e-16	430	190	29	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	ERVK-6 HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ERVK-7 ERVK-10 ADAM8 ADAM28 ST14 PRSS36 F12 DHH HPN PRSS21 PLAU KLK5 TPSG1 COPS5 PRSS41 KLK12 CELA2B OVCH1 USP10 GZMH USP40 ERVK-8 PSMD14	2.24e-14	654	190	32	GO:0008233
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	3.26e-08	11	190	5	GO:0004523
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 AGO2 ERVK-7 ERVK-10 ERVK-11 DICER1 ERVK-8	5.11e-08	37	190	7	GO:0016891
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	1.38e-07	14	190	5	GO:0003964
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 AGO2 ERVK-7 ERVK-10 ERVK-11 DICER1 ERVK-8	2.47e-07	46	190	7	GO:0016893
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	1.33e-06	21	190	5	GO:0035613
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 AGO2 ERVK-7 ERVK-10 ERVK-11 DICER1 ERVK-8	1.03e-05	79	190	7	GO:0004521
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	2.88e-05	38	190	5	GO:0034061
GeneOntologyMolecularFunction	calcium ion binding	TPO PRSS1 PRSS2 ADAM8 TENM2 F12 RYR1 ITPR1 JAG2 DHH PADI1 SELE HSPG2 DLL4 GNPTAB ITLN2 EGFEM1P RASGRP1 SYT8 AGRN	3.24e-05	749	190	20	GO:0005509
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 AGO2 ERVK-7 ERVK-10 ERVK-11 DICER1 ERVK-8 CNOT1	4.83e-05	136	190	8	GO:0004540
GeneOntologyMolecularFunction	scavenger receptor activity	CD163 DMBT1 EGFEM1P MSR1	1.17e-04	27	190	4	GO:0005044
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 AGO2 ERVK-7 ERVK-10 ERVK-11 DICER1 ERVK-8	3.28e-04	136	190	7	GO:0004519
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.10e-04	37	190	4	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.55e-04	38	190	4	GO:0070001
GeneOntologyMolecularFunction	ISG15 transferase activity	UBE2E1 HERC5	5.34e-04	4	190	2	GO:0042296
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH9 DNHD1 DNAH17	6.23e-04	18	190	3	GO:0008569
GeneOntologyMolecularFunction	immunoglobulin receptor binding	ADAM8 ADAM28 FLNA	9.94e-04	21	190	3	GO:0034987
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 AGO2 ERVK-7 ERVK-10 ERVK-11 DICER1 ERVK-8 CNOT1	1.70e-03	231	190	8	GO:0004518
GeneOntologyMolecularFunction	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	INPP5B INPP5K	1.83e-03	7	190	2	GO:0052659
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	ERVK-6 AGO2 INPP5B INPP5K ERVK-7 ERVK-10 SBF1 PTPRH PLCL2 ERVK-11 PPP4R1 DICER1 ARSG LPIN3 MTMR4 ERVK-8 CNOT1	1.87e-03	807	190	17	GO:0016788
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate phosphatase activity	INPP5B INPP5K MTMR4	2.10e-03	27	190	3	GO:0034593
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THSD4 FGB DMBT1 HSPG2 FN1 LAMA2 AGRN	2.19e-03	188	190	7	GO:0005201
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH9 DNHD1 DNAH17	2.33e-03	28	190	3	GO:0051959
GeneOntologyMolecularFunction	inositol-polyphosphate 5-phosphatase activity	INPP5B INPP5K	2.43e-03	8	190	2	GO:0004445
GeneOntologyMolecularFunction	inositol-1,4,5-trisphosphate 5-phosphatase activity	INPP5B INPP5K	2.43e-03	8	190	2	GO:0052658
GeneOntologyMolecularFunction	MHC class II protein binding	LAG3 FCRL6	2.43e-03	8	190	2	GO:0042289
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	7.43e-08	13	189	5	GO:0015074
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-11 USP10 ERVK-8	4.87e-06	48	189	6	GO:0000731
GeneOntologyBiologicalProcess	blood coagulation, fibrin clot formation	F12 F13A1 FGB FLNA	1.48e-05	17	189	4	GO:0072378
GeneOntologyBiologicalProcess	zymogen activation	HGFAC PRSS1 F12 HPN FGB PLAU	2.88e-05	65	189	6	GO:0031638
GeneOntologyBiologicalProcess	protein activation cascade	F12 F13A1 FGB FLNA	6.29e-05	24	189	4	GO:0072376
GeneOntologyCellularComponent	cell surface	TPO IL12RB1 LRRC32 TSHR ITGA2B THSD1 ADAM8 RS1 ITGAX ADAM28 ST14 CD163 MRC2 CD163L1 HPN FGB SCART1 PLAU CA4 SELE ISLR2 LAG3 FCRL6 SLC6A1 ROBO2 AGRN	6.84e-06	1111	187	26	GO:0009986
GeneOntologyCellularComponent	external encapsulating structure	THSD4 PRSS1 PRSS2 LRRC32 CELA2A F12 F13A1 FCGBP FGB DMBT1 HSPG2 LAMB4 FN1 LAMA2 CELA2B ITLN2 PKHD1L1 ADAMTSL5 AGRN	7.52e-06	658	187	19	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	THSD4 PRSS1 PRSS2 CELA2A F12 F13A1 FGB DMBT1 HSPG2 LAMB4 FN1 LAMA2 CELA2B ITLN2 ADAMTSL5 AGRN	2.38e-05	530	187	16	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	THSD4 PRSS1 PRSS2 LRRC32 CELA2A F12 F13A1 FCGBP FGB DMBT1 HSPG2 LAMB4 FN1 LAMA2 CELA2B ITLN2 ADAMTSL5 AGRN	2.60e-05	656	187	18	GO:0031012
GeneOntologyCellularComponent	side of membrane	IL12RB1 LRRC32 ITGA2B RS1 ITGAX ST14 CD163 RYR1 JAK3 CD163L1 PRSS21 FGB SCART1 PLAU GNRH1 CA4 SELE PRSS41 LAG3 ITLN2 FCRL6	3.92e-05	875	187	21	GO:0098552
GeneOntologyCellularComponent	external side of plasma membrane	IL12RB1 LRRC32 ITGA2B RS1 ITGAX ST14 CD163 CD163L1 FGB SCART1 PLAU CA4 SELE LAG3 FCRL6	7.05e-05	519	187	15	GO:0009897
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGA2B ITGAX PLAU PLP1 LAMA2	1.84e-04	59	187	5	GO:0098636
GeneOntologyCellularComponent	rough endoplasmic reticulum	HGFAC F12 GNRH1 CA4 LYZ	2.70e-04	64	187	5	GO:0005791
GeneOntologyCellularComponent	secretory granule	PRSS2 KLK10 PSMA2 ITGA2B ADAM8 ITGAX F13A1 ITPR1 MAGED2 AGL FGB PLAU KLK5 DMBT1 CA4 FN1 KLK12 EEF2 SYT8 LYZ PSMD14	3.04e-04	1014	187	21	GO:0030141
GeneOntologyCellularComponent	secretory vesicle	PRSS2 KLK10 DISC1 SLC6A17 PSMA2 ITGA2B ADAM8 ITGAX F13A1 ITPR1 MAGED2 AGL FGB PLAU KLK5 DMBT1 COPS5 CA4 FN1 KLK12 EEF2 SYT8 LYZ PSMD14	3.25e-04	1246	187	24	GO:0099503
GeneOntologyCellularComponent	secretory granule lumen	PRSS2 PSMA2 F13A1 MAGED2 AGL FGB FN1 EEF2 LYZ PSMD14	7.19e-04	325	187	10	GO:0034774
GeneOntologyCellularComponent	keratohyalin granule	CELA2A CELA2B	7.82e-04	5	187	2	GO:0036457
GeneOntologyCellularComponent	Mon1-Ccz1 complex	CCZ1B CCZ1	7.82e-04	5	187	2	GO:0035658
GeneOntologyCellularComponent	cytoplasmic vesicle lumen	PRSS2 PSMA2 F13A1 MAGED2 AGL FGB FN1 EEF2 LYZ PSMD14	8.08e-04	330	187	10	GO:0060205
GeneOntologyCellularComponent	vesicle lumen	PRSS2 PSMA2 F13A1 MAGED2 AGL FGB FN1 EEF2 LYZ PSMD14	8.46e-04	332	187	10	GO:0031983
GeneOntologyCellularComponent	sarcoplasmic reticulum	RYR1 ITPR1 AGL CA4 FSD2	1.17e-03	88	187	5	GO:0016529
GeneOntologyCellularComponent	dynein complex	DISC1 DNAH9 DNHD1 DNAH17	1.38e-03	54	187	4	GO:0030286
GeneOntologyCellularComponent	axonemal dynein complex	DNAH9 DNHD1 DNAH17	1.40e-03	25	187	3	GO:0005858
GeneOntologyCellularComponent	platelet alpha granule	ITGA2B F13A1 MAGED2 FGB FN1	1.49e-03	93	187	5	GO:0031091
GeneOntologyCellularComponent	blood microparticle	PRSS1 TMPRSS13 ITGA2B F13A1 FGB FN1	1.90e-03	144	187	6	GO:0072562
GeneOntologyCellularComponent	fibrinogen complex	FGB FN1	2.15e-03	8	187	2	GO:0005577
Domain	TRYPSIN_HIS	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	3.25e-22	103	181	21	IPR018114
Domain	TRYPSIN_SER	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	6.19e-22	106	181	21	PS00135
Domain	TRYPSIN_HIS	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	7.64e-22	107	181	21	PS00134
Domain	Peptidase_S1A	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	2.58e-21	113	181	21	IPR001314
Domain	TRYPSIN_DOM	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	3.80e-21	115	181	21	PS50240
Domain	Tryp_SPc	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	5.56e-21	117	181	21	SM00020
Domain	Trypsin_dom	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	1.17e-20	121	181	21	IPR001254
Domain	Trypsin	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	1.17e-20	121	181	21	PF00089
Domain	TRYPSIN_SER	HGFAC PRSS1 PRSS2 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 PRSS41 KLK12 CELA2B OVCH1 GZMH	1.67e-20	90	181	19	IPR033116
Domain	Peptidase_S1_PA	HGFAC PRSS1 PRSS2 KLK10 TMPRSS13 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN PRSS21 PLAU KLK5 TPSG1 PRSS41 KLK12 CELA2B OVCH1 GZMH	1.67e-20	123	181	21	IPR009003
Domain	EGF_1	TPO HGFAC ADAM8 TENM2 ADAM28 F12 JAG2 PLAU SELE HSPG2 LAMB4 FN1 DLL4 CNTNAP1 LAMA2 MUC12 AGRN	4.95e-10	255	181	17	PS00022
Domain	EGF-like_CS	TPO HGFAC ADAM8 TENM2 ADAM28 F12 JAG2 PLAU SELE HSPG2 LAMB4 FN1 DLL4 CNTNAP1 LAMA2 MUC12 AGRN	7.07e-10	261	181	17	IPR013032
Domain	-	TMPRSS13 CD163 SSC4D CD163L1 HPN DMBT1 MSR1	2.96e-09	25	181	7	3.10.250.10
Domain	SR	TMPRSS13 CD163 SSC4D CD163L1 HPN DMBT1 MSR1	2.96e-09	25	181	7	SM00202
Domain	SRCR-like_dom	TMPRSS13 CD163 SSC4D CD163L1 HPN DMBT1 MSR1	4.02e-09	26	181	7	IPR017448
Domain	SRCR_1	TMPRSS13 CD163 SSC4D CD163L1 HPN DMBT1 MSR1	4.02e-09	26	181	7	PS00420
Domain	SRCR_2	TMPRSS13 CD163 SSC4D CD163L1 HPN DMBT1 MSR1	4.02e-09	26	181	7	PS50287
Domain	SRCR	TMPRSS13 CD163 SSC4D CD163L1 HPN DMBT1 MSR1	5.39e-09	27	181	7	IPR001190
Domain	EGF_2	TPO HGFAC ADAM8 TENM2 ADAM28 F12 JAG2 PLAU SELE HSPG2 LAMB4 DLL4 CNTNAP1 LAMA2 MUC12 AGRN	6.81e-09	265	181	16	PS01186
Domain	EGF	TPO HGFAC ADAM8 TENM2 ADAM28 F12 JAG2 FCGBP PLAU SELE HSPG2 DLL4 CNTNAP1 LAMA2 AGRN	9.75e-09	235	181	15	SM00181
Domain	EGF-like_dom	TPO HGFAC ADAM8 TENM2 ADAM28 F12 JAG2 FCGBP PLAU SELE HSPG2 DLL4 CNTNAP1 LAMA2 AGRN	2.12e-08	249	181	15	IPR000742
Domain	EGF_3	TPO HGFAC ADAM8 TENM2 ADAM28 F12 JAG2 PLAU SELE HSPG2 DLL4 CNTNAP1 AGRN	5.09e-07	235	181	13	PS50026
Domain	SRCR	CD163 SSC4D CD163L1 DMBT1 MSR1	1.45e-06	21	181	5	PF00530
Domain	FN1_2	HGFAC F12 FN1	3.56e-06	4	181	3	PS51091
Domain	fn1	HGFAC F12 FN1	3.56e-06	4	181	3	PF00039
Domain	Fibronectin_type1	HGFAC F12 FN1	3.56e-06	4	181	3	IPR000083
Domain	FN1	HGFAC F12 FN1	3.56e-06	4	181	3	SM00058
Domain	FN1_1	HGFAC F12 FN1	3.56e-06	4	181	3	PS01253
Domain	-	HGFAC F12 MRC2 FN1	5.70e-06	13	181	4	2.10.10.10
Domain	FN_type2_col-bd	HGFAC F12 MRC2 FN1	7.92e-06	14	181	4	IPR000562
Domain	FN2_2	HGFAC F12 MRC2 FN1	7.92e-06	14	181	4	PS51092
Domain	FN2_1	HGFAC F12 MRC2 FN1	7.92e-06	14	181	4	PS00023
Domain	fn2	HGFAC F12 MRC2 FN1	7.92e-06	14	181	4	PF00040
Domain	FN2	HGFAC F12 MRC2 FN1	7.92e-06	14	181	4	SM00059
Domain	Kringle-like	HGFAC F12 MRC2 PLAU FN1	1.32e-05	32	181	5	IPR013806
Domain	EGF	HGFAC F12 JAG2 SELE HSPG2 DLL4 CNTNAP1 AGRN	3.16e-05	126	181	8	PF00008
Domain	SEA	ST14 HSPG2 MUC12 AGRN	5.44e-05	22	181	4	PF01390
Domain	SEA	ST14 HSPG2 MUC12 AGRN	6.54e-05	23	181	4	PS50024
Domain	SEA_dom	ST14 HSPG2 MUC12 AGRN	6.54e-05	23	181	4	IPR000082
Domain	Urea_transporter	SLC14A1 SLC14A2	9.34e-05	2	181	2	IPR004937
Domain	Coagulation_fac_XIIa/HGFA	HGFAC F12	9.34e-05	2	181	2	IPR014394
Domain	UT	SLC14A1 SLC14A2	9.34e-05	2	181	2	PF03253
Domain	DUF1712	CCZ1B CCZ1	9.34e-05	2	181	2	PF08217
Domain	DUF1712_fun	CCZ1B CCZ1	9.34e-05	2	181	2	IPR013176
Domain	Laminin_G_1	HSPG2 LAMA2 AGRN	1.39e-04	11	181	3	PF00054
Domain	EGF_CA	TPO TENM2 F12 JAG2 HSPG2 DLL4 AGRN	1.88e-04	122	181	7	SM00179
Domain	EGF_LAM_2	HSPG2 LAMB4 LAMA2 AGRN	1.92e-04	30	181	4	PS50027
Domain	EGF_LAM_1	HSPG2 LAMB4 LAMA2 AGRN	1.92e-04	30	181	4	PS01248
Domain	EGF-like_Ca-bd_dom	TPO TENM2 F12 JAG2 HSPG2 DLL4 AGRN	2.07e-04	124	181	7	IPR001881
Domain	EGF_Lam	HSPG2 LAMB4 LAMA2 AGRN	3.53e-04	35	181	4	SM00180
Domain	Laminin_EGF	HSPG2 LAMB4 LAMA2 AGRN	3.53e-04	35	181	4	PF00053
Domain	LAM_G_DOMAIN	HSPG2 CNTNAP1 LAMA2 AGRN	4.87e-04	38	181	4	PS50025
Domain	Laminin_EGF	HSPG2 LAMB4 LAMA2 AGRN	4.87e-04	38	181	4	IPR002049
Domain	Kringle_CS	HGFAC F12 PLAU	5.51e-04	17	181	3	IPR018056
Domain	KRINGLE_1	HGFAC F12 PLAU	5.51e-04	17	181	3	PS00021
Domain	KR	HGFAC F12 PLAU	5.51e-04	17	181	3	SM00130
Domain	Kringle	HGFAC F12 PLAU	5.51e-04	17	181	3	IPR000001
Domain	KRINGLE_2	HGFAC F12 PLAU	5.51e-04	17	181	3	PS50070
Domain	Kringle	HGFAC F12 PLAU	5.51e-04	17	181	3	PF00051
Domain	EFG_IV	EFTUD2 EEF2	5.53e-04	4	181	2	SM00889
Domain	DSL	JAG2 DLL4	5.53e-04	4	181	2	PF01414
Domain	EFG_IV	EFTUD2 EEF2	5.53e-04	4	181	2	PF03764
Domain	Transl_elong_EFG/EF2_IV	EFTUD2 EEF2	5.53e-04	4	181	2	IPR005517
Domain	DSL	JAG2 DLL4	5.53e-04	4	181	2	SM00051
Domain	NA_NEUROTRAN_SYMP_2	SLC6A17 SLC6A18 SLC6A1	6.56e-04	18	181	3	PS00754
Domain	SNF	SLC6A17 SLC6A18 SLC6A1	7.74e-04	19	181	3	PF00209
Domain	Na/ntran_symport	SLC6A17 SLC6A18 SLC6A1	7.74e-04	19	181	3	IPR000175
Domain	NA_NEUROTRAN_SYMP_1	SLC6A17 SLC6A18 SLC6A1	7.74e-04	19	181	3	PS00610
Domain	NA_NEUROTRAN_SYMP_3	SLC6A17 SLC6A18 SLC6A1	7.74e-04	19	181	3	PS50267
Domain	LamG	HSPG2 CNTNAP1 LAMA2 AGRN	8.56e-04	44	181	4	SM00282
Domain	DSL	JAG2 DLL4	9.16e-04	5	181	2	PS51051
Domain	Notch_ligand_N	JAG2 DLL4	9.16e-04	5	181	2	IPR011651
Domain	MNNL	JAG2 DLL4	9.16e-04	5	181	2	PF07657
Domain	Na/ntran_symport_orphan	SLC6A17 SLC6A18	9.16e-04	5	181	2	IPR002438
Domain	DSL	JAG2 DLL4	9.16e-04	5	181	2	IPR001774
Domain	EFG_II	EFTUD2 EEF2	9.16e-04	5	181	2	PF14492
Domain	-	EFTUD2 EEF2 TOP2B	1.05e-03	21	181	3	3.30.230.10
Domain	Ribosomal_S5_D2-typ_fold_subgr	EFTUD2 EEF2 TOP2B	1.20e-03	22	181	3	IPR014721
Domain	RIH_assoc-dom	RYR1 ITPR1	1.37e-03	6	181	2	IPR013662
Domain	EFG_C	EFTUD2 EEF2	1.37e-03	6	181	2	PF00679
Domain	SUN	SUN2 SUN5	1.37e-03	6	181	2	PS51469
Domain	Ins145_P3_rec	RYR1 ITPR1	1.37e-03	6	181	2	PF08709
Domain	RIH_assoc	RYR1 ITPR1	1.37e-03	6	181	2	PF08454
Domain	EFG_III-V	EFTUD2 EEF2	1.37e-03	6	181	2	IPR009022
Domain	RIH_dom	RYR1 ITPR1	1.37e-03	6	181	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 ITPR1	1.37e-03	6	181	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 ITPR1	1.37e-03	6	181	2	IPR015925
Domain	EFG_C	EFTUD2 EEF2	1.37e-03	6	181	2	SM00838
Domain	-	RYR1 ITPR1	1.37e-03	6	181	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 ITPR1	1.37e-03	6	181	2	PF01365
Domain	-	EFTUD2 EEF2	1.90e-03	7	181	2	3.30.70.240
Domain	-	SLC14A1 SLC14A2	1.90e-03	7	181	2	1.10.3430.10
Domain	EFG_V	EFTUD2 EEF2	1.90e-03	7	181	2	IPR000640
Domain	Ammonium/urea_transptr	SLC14A1 SLC14A2	1.90e-03	7	181	2	IPR029020
Domain	SUN_dom	SUN2 SUN5	1.90e-03	7	181	2	IPR012919
Domain	Sad1_UNC	SUN2 SUN5	1.90e-03	7	181	2	PF07738
Domain	Fibrinogen_C	FGB CNTNAP1 ITLN2	2.21e-03	27	181	3	PF00147
Domain	-	HSPG2 CNTNAP1 LAMA2 LRBA AGRN	2.32e-03	95	181	5	2.60.120.200
Domain	Laminin_G	HSPG2 CNTNAP1 LAMA2 AGRN	2.41e-03	58	181	4	IPR001791
Domain	LAMININ_IVA	HSPG2 LAMA2	2.52e-03	8	181	2	PS51115
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	PRSS1 PRSS2 CELA2A F13A1 FGB DMBT1 HSPG2 FN1 LAMA2 CELA2B AGRN	4.74e-09	175	194	11	28071719
Pubmed	A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).	IL12RB1 F12 F13A1 FGB FGF2 PLAU SELE HSPG2 FN1 LYZ	1.06e-07	186	194	10	20673868
Pubmed	Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.	IL12RB1 F12 F13A1 FGB FGF2 PLAU SELE HSPG2 FN1 LYZ	1.06e-07	186	194	10	20452482
Pubmed	Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns.	PRSS22 PRSS21 TPSG1 PRSS41	1.92e-07	10	194	4	14583634
Pubmed	CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity.	ITGA2B FGB PLAU FN1	4.49e-07	12	194	4	27140400
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	F13A1 FGB DMBT1 HSPG2 FN1 LAMA2 ITLN2 ADAMTSL5 AGRN	4.55e-07	167	194	9	22159717
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	6.81e-07	4	194	3	10469592
Pubmed	Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.	ST14 HPN PLAU	6.81e-07	4	194	3	20015050
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	HSPG2 FN1 LAMA2 AGRN	1.62e-06	16	194	4	17948866
Pubmed	PRSS1-Related Hereditary Pancreatitis	PRSS1 PRSS2 CTRC	1.69e-06	5	194	3	22379635
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	HGFAC ITGA2B F12 F13A1 CD163 FCGBP FGB HSPG2 FN1 LAMA2	2.04e-06	257	194	10	16335952
Pubmed	Vector-capping: a simple method for preparing a high-quality full-length cDNA library.	FLNA FN1 AGRN	3.38e-06	6	194	3	16106752
Pubmed	The new human kallikrein gene family: implications in carcinogenesis.	KLK10 KLK5 KLK12	3.38e-06	6	194	3	10675891
Pubmed	Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.	PRSS1 PRSS2 CTRC	3.38e-06	6	194	3	23814066
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	THSD4 TBC1D2B RYR1 MRC2 SDK1 HSPG2 FLNA FN1 HERC5	3.55e-06	214	194	9	22199357
Pubmed	Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.	HSPG2 LAMA2 AGRN	5.88e-06	7	194	3	11802174
Pubmed	Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes.	PRSS2 CELA2A CELA2B	5.88e-06	7	194	3	3641189
Pubmed	Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4.	KLK10 KLK5 KLK12	5.88e-06	7	194	3	10969073
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EFTUD2 DNHD1 FLNA PCARE OVCH1 LPIN3 EEF2 LRBA TOP2B	7.33e-06	234	194	9	36243803
Pubmed	Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth.	HGFAC ST14 HPN	9.38e-06	8	194	3	17174946
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	PRSS1 F13A1 FGB HSPG2 FN1 LAMA2 AGRN	1.14e-05	135	194	7	28675934
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	THSD4 TCTN3 PRSS22 BIRC7 THSD1 SEMA5B CD163L1 DEFB123 PRSS21 SEMA4A KLK5 DNHD1 ISLR2 DLL4 KLK12 ITLN2 ARSG LYG1	1.15e-05	985	194	18	12975309
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERV3-1 ERVK-7 ERVK-10 ERVK-11 ERVK-8	1.51e-05	94	194	6	21542922
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	TPO IL12RB1 LRRC32 BIRC7 PTGIR F13A1 CD163 JAG2 SSC4D FCGBP MAGED2 CD163L1 FGB SEMA4A LAG3 SUN5	1.74e-05	824	194	16	20237496
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	KNTC1 PHKB SBF1 FLNA CNTNAP1 DICER1 CNOT1 TOP2B	1.93e-05	202	194	8	33005030
Pubmed	Organization and evolution of the glandular kallikrein locus in Mus musculus.	KLK10 KLK5 KLK12	1.99e-05	10	194	3	12437987
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	HSPG2 FN1 LAMA2 AGRN	2.00e-05	29	194	4	22613833
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	THSD4 F12 F13A1 FGB HSPG2 FN1 LAMA2	2.57e-05	153	194	7	25037231
Pubmed	Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.	PRSS1 PRSS2 CTRC	2.73e-05	11	194	3	19096130
Pubmed	Filamin A Regulates Neutrophil Adhesion, Production of Reactive Oxygen Species, and Neutrophil Extracellular Trap Release.	FLNA LYZ	3.10e-05	2	194	2	28986439
Pubmed	Initiation of plasminogen activation on the surface of monocytes expressing the type II transmembrane serine protease matriptase.	ST14 PLAU	3.10e-05	2	194	2	16794252
Pubmed	Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.	HSPG2 AGRN	3.10e-05	2	194	2	25506919
Pubmed	TSH receptor interaction with the extracellular matrix: role on constitutive activity and sensitivity to hormonal stimulation.	TSHR FN1	3.10e-05	2	194	2	11981027
Pubmed	[Expression of Livin in laryngeal squamous cell carcinoma and relationship with bFGF].	BIRC7 FGF2	3.10e-05	2	194	2	18476630
Pubmed	The coexistence of a novel inactivating mutant thyrotropin receptor allele with two thyroid peroxidase mutations: a genotype-phenotype correlation.	TPO TSHR	3.10e-05	2	194	2	21490078
Pubmed	Fibronectin fragments and the cleaving enzyme ADAM-8 in the degenerative human intervertebral disc.	ADAM8 FN1	3.10e-05	2	194	2	25010013
Pubmed	Tyrosinase is the modifier of retinoschisis in mice.	RS1 TYR	3.10e-05	2	194	2	20876567
Pubmed	Role of thin descending limb urea transport in renal urea handling and the urine concentrating mechanism.	SLC14A1 SLC14A2	3.10e-05	2	194	2	21849488
Pubmed	MicroRNA-Independent Modulation of DICER1 Expression by hAgo2.	AGO2 DICER1	3.10e-05	2	194	2	32778571
Pubmed	Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.	IRF5 LYZ	3.10e-05	2	194	2	25939064
Pubmed	Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13.3 by in situ hybridization and somatic cell hybrid analysis.	CD163 CD163L1	3.10e-05	2	194	2	11124526
Pubmed	Filamin A protects cells against force-induced apoptosis by stabilizing talin- and vinculin-containing cell adhesions.	FLNA LYZ	3.10e-05	2	194	2	24097310
Pubmed	Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.	PRSS1 PRSS2	3.10e-05	2	194	2	36191639
Pubmed	Cloning and functional expression of a urea transporter from human bone marrow cells.	SLC14A1 SLC14A2	3.10e-05	2	194	2	7989337
Pubmed	Serotonin (5-HT) inhibits Factor XIII-A-mediated plasma fibronectin matrix assembly and crosslinking in osteoblast cultures via direct competition with transamidation.	F13A1 FN1	3.10e-05	2	194	2	25460579
Pubmed	A novel, specific pro-urokinase complex on monocyte-like cells, detected by transglutaminase-catalyzed cross-linking.	MRC2 PLAU	3.10e-05	2	194	2	7904248
Pubmed	IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.	IRF5 LYZ	3.10e-05	2	194	2	27942586
Pubmed	Molecular screening of the TSH receptor (TSHR) and thyroid peroxidase (TPO) genes in Korean patients with nonsyndromic congenital hypothyroidism.	TPO TSHR	3.10e-05	2	194	2	21707688
Pubmed	Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.	PRSS1 PRSS2	3.10e-05	2	194	2	20484960
Pubmed	Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12.	KLK5 KLK12	3.10e-05	2	194	2	23612974
Pubmed	Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.	DLL4 LYZ	3.10e-05	2	194	2	27898698
Pubmed	Ago2 and GW182 expression in mouse preimplantation embryos: a link between microRNA biogenesis and GW182 protein synthesis.	AGO2 DICER1	3.10e-05	2	194	2	20353723
Pubmed	Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice.	CELA2A CELA2B	3.10e-05	2	194	2	28386233
Pubmed	Developmental expression of HERV-R (ERV3) and HERV-K in human tissue.	ERVK-6 ERV3-1	3.10e-05	2	194	2	12083821
Pubmed	mRNA-Seq whole-transcriptome analysis of a single cell.	AGO2 DICER1	3.10e-05	2	194	2	19349980
Pubmed	POH1 deubiquitinates pro-interleukin-1β and restricts inflammasome activity.	LYZ PSMD14	3.10e-05	2	194	2	30315153
Pubmed	Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).	PRSS1 PRSS2	3.10e-05	2	194	2	14695529
Pubmed	Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.	PRSS1 CTRC	3.10e-05	2	194	2	22539344
Pubmed	Expression of urea transporters in potassium-depleted mouse kidney.	SLC14A1 SLC14A2	3.10e-05	2	194	2	12952854
Pubmed	Water transport mediated by murine urea transporters: implications for urine concentration mechanisms.	SLC14A1 SLC14A2	3.10e-05	2	194	2	32661130
Pubmed	Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas.	CELA2A CELA2B	3.10e-05	2	194	2	3646943
Pubmed	Essential Role for endogenous siRNAs during meiosis in mouse oocytes.	AGO2 DICER1	3.10e-05	2	194	2	25695507
Pubmed	Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.	PRSS1 CTRC	3.10e-05	2	194	2	28502372
Pubmed	Fibrinogen β chain and FXIII polymorphisms affect fibrin clot properties in acute pulmonary embolism.	F13A1 FGB	3.10e-05	2	194	2	34783023
Pubmed	Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.	PRSS1 PRSS2	3.10e-05	2	194	2	18461367
Pubmed	Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.	PRSS1 PRSS2	3.10e-05	2	194	2	15651064
Pubmed	Salivary KLK5 and uPA are potential biomarkers for malignant transformation of OLK and OLP.	PLAU KLK5	3.10e-05	2	194	2	33896830
Pubmed	Differential regulation of Notch ligands in dendritic cells upon interaction with T helper cells.	JAG2 DLL4	3.10e-05	2	194	2	21352254
Pubmed	Immunoreactive anionic and cationic trypsin in human serum.	PRSS1 PRSS2	3.10e-05	2	194	2	2598466
Pubmed	Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.	PRSS1 PRSS2	3.10e-05	2	194	2	35089416
Pubmed	Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.	SCAP LYZ	3.10e-05	2	194	2	26686653
Pubmed	Generation and phenotypic analysis of mice lacking all urea transporters.	SLC14A1 SLC14A2	3.10e-05	2	194	2	27914708
Pubmed	MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice.	DICER1 LYZ	3.10e-05	2	194	2	33450179
Pubmed	Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase.	ST14 PLAU	3.10e-05	2	194	2	14747469
Pubmed	Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP(3) type 1 receptor.	RYR1 ITPR1	3.10e-05	2	194	2	12654335
Pubmed	Decreased AGO2 and DCR1 in PBMCs from War Veterans with PTSD leads to diminished miRNA resulting in elevated inflammation.	AGO2 DICER1	3.10e-05	2	194	2	28850112
Pubmed	Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3.	SLC14A1 SLC14A2	3.10e-05	2	194	2	26407594
Pubmed	Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.	LAMA2 AGRN	3.10e-05	2	194	2	16103356
Pubmed	Differential deposition of basement membrane components during formation of the caudal neural tube in the mouse embryo.	HSPG2 FN1	3.10e-05	2	194	2	3665768
Pubmed	Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.	AGO2 DICER1	3.10e-05	2	194	2	20975942
Pubmed	Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.	PRSS1 PRSS2	3.10e-05	2	194	2	33202925
Pubmed	Down-regulation of Dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer.	AGO2 DICER1	3.10e-05	2	194	2	25135428
Pubmed	Increased risk for oral cancer is associated with coagulation factor XIII but not with factor XII.	F12 F13A1	3.10e-05	2	194	2	17982641
Pubmed	Megakaryocyte-matrix interaction within bone marrow: new roles for fibronectin and factor XIII-A.	F13A1 FN1	3.10e-05	2	194	2	21131589
Pubmed	Pro-urokinase-type plasminogen activator is a substrate for hepsin.	HPN PLAU	3.10e-05	2	194	2	16908524
Pubmed	Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.	COPS5 LYZ	3.10e-05	2	194	2	28292897
Pubmed	Dicer knockdown induces fibronectin-1 expression in HEK293T cells via induction of Egr1.	FN1 DICER1	3.10e-05	2	194	2	19914350
Pubmed	Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.	FGF2 DICER1	3.10e-05	2	194	2	24142921
Pubmed	Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans.	CELA2A CELA2B	3.10e-05	2	194	2	16327289
Pubmed	Presence and localization of a 30-kDa basic fibroblast growth factor-like protein in rodent testes.	FGF2 HPS6	3.10e-05	2	194	2	1855483
Pubmed	The murine urea transporter genes Slc14a1 and Slc14a2 occur in tandem on chromosome 18.	SLC14A1 SLC14A2	3.10e-05	2	194	2	10640821
Pubmed	Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.	PRSS1 PRSS2	3.10e-05	2	194	2	27846138
Pubmed	The RNA-RNA base pairing potential of human Dicer and Ago2 proteins.	AGO2 DICER1	3.10e-05	2	194	2	31655860
Pubmed	Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.	PRSS1 PRSS2	3.10e-05	2	194	2	15776435
Pubmed	Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.	PRSS1 CTRC	3.10e-05	2	194	2	27129265
Pubmed	The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.	SCAP LYZ	3.10e-05	2	194	2	37267109
Pubmed	Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes.	SLC14A1 SLC14A2	3.10e-05	2	194	2	18256317
Pubmed	Functional differentiation of the human red blood cell and kidney urea transporters.	SLC14A1 SLC14A2	3.10e-05	2	194	2	8997401
Pubmed	Molecular characterization of a new urea transporter in the human kidney.	SLC14A1 SLC14A2	3.10e-05	2	194	2	8647271
Pubmed	Regulation of fibroblast growth factor-2 by an endogenous antisense RNA and by argonaute-2.	AGO2 FGF2	3.10e-05	2	194	2	20197313
Interaction	TPSG1 interactions	PRSS22 PRSS21 TPSG1 PRSS41	4.48e-07	8	183	4	int:TPSG1
Interaction	FBXO2 interactions	THSD4 IL12RB1 ST14 JAG2 UBE2E1 MRC2 KLK5 HSPG2 FN1 GNPTAB CNTNAP1 LAG3 SCAP GZMH AGRN	5.54e-06	411	183	15	int:FBXO2
Interaction	FKBP14 interactions	TMPRSS13 DHH SUN2 HPN PRSS21 DMBT1 LYZ	1.05e-05	83	183	7	int:FKBP14
GeneFamily	Proteases, serine	PRSS1 PRSS2 TMPRSS13 PRSS22 ST14 PRSS36 HPN PRSS21 TPSG1 PRSS41	2.06e-11	63	128	10	738
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	CD163 SSC4D CD163L1 MSR1	3.71e-05	27	128	4	1253
GeneFamily	Kallikreins	KLK10 KLK5 KLK12	1.81e-04	16	128	3	616
GeneFamily	Fibronectin type III domain containing	IL12RB1 PTPRH SDK1 FN1 FSD2 ROBO2	9.76e-04	160	128	6	555
GeneFamily	ADAMTS like	THSD4 ADAMTSL5	1.02e-03	7	128	2	947
GeneFamily	Blood group antigens\|CD molecules\|Proteoglycans	HSPG2 AGRN	1.02e-03	7	128	2	570
GeneFamily	Phosphoinositide phosphatases	INPP5B INPP5K MTMR4	1.48e-03	32	128	3	1079
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IL12RB1 ITGA2B ADAM8 ITGAX CD163 MRC2 SELE LAG3 MSR1	1.97e-03	394	128	9	471
GeneFamily	Laminin subunits	LAMB4 LAMA2	3.13e-03	12	128	2	626
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	SBF1 MTMR4	4.92e-03	15	128	2	903
Coexpression	NABA_MATRISOME	VWA5B2 THSD4 TPO HGFAC PRSS1 PRSS2 CELA2A ADAM8 ADAM28 ST14 F12 F13A1 DHH SEMA5B FGB FGF2 PLAU SEMA4A DMBT1 HSPG2 LAMB4 FN1 LAMA2 MUC12 CELA2B ITLN2 ADAMTSL5 AGRN	1.29e-09	1026	188	28	M5889
Coexpression	NABA_MATRISOME	VWA5B2 THSD4 TPO HGFAC PRSS1 PRSS2 CELA2A ADAM8 ADAM28 ST14 F12 F13A1 DHH SEMA5B FGB FGF2 PLAU SEMA4A DMBT1 HSPG2 FN1 LAMA2 CELA2B ITLN2 EGFEM1P ADAMTSL5 AGRN	3.91e-09	1008	188	27	MM17056
Coexpression	NABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS	PRSS1 PRSS2 CELA2A DMBT1 CELA2B	1.05e-06	26	188	5	MM17051
Coexpression	NABA_ECM_REGULATORS	PRSS1 PRSS2 CELA2A ADAM8 ADAM28 ST14 F12 F13A1 PLAU CELA2B ADAMTSL5	1.29e-06	238	188	11	M3468
Coexpression	NABA_ECM_REGULATORS	PRSS1 PRSS2 CELA2A ADAM8 ADAM28 ST14 F12 F13A1 PLAU CELA2B ADAMTSL5	1.52e-06	242	188	11	MM17062
Coexpression	NABA_MATRISOME_ASSOCIATED	TPO HGFAC PRSS1 PRSS2 CELA2A ADAM8 ADAM28 ST14 F12 F13A1 DHH SEMA5B FGF2 PLAU SEMA4A MUC12 CELA2B ITLN2 ADAMTSL5	2.17e-06	751	188	19	M5885
Coexpression	BUSSLINGER_DUODENAL_PANETH_CELLS	PRSS1 FCGBP ITLN2 LYZ	3.29e-06	15	188	4	M40030
Coexpression	NABA_MATRISOME_ASSOCIATED	TPO HGFAC PRSS1 PRSS2 CELA2A ADAM8 ADAM28 ST14 F12 F13A1 DHH SEMA5B FGF2 PLAU SEMA4A CELA2B ITLN2 ADAMTSL5	6.73e-06	738	188	18	MM17058
Coexpression	GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN	TMPRSS13 FAXC ADAM8 ST14 HSD3B1 GNPTAB MSR1 RASGRP1 GZMH	1.50e-05	200	188	9	M5045
Coexpression	CAIRO_LIVER_DEVELOPMENT_DN	KNTC1 HGFAC GAMT GCDH F12 HPN FGB FN1 LYZ	3.80e-05	225	188	9	M6175
Coexpression	DESCARTES_FETAL_PANCREAS_MYELOID_CELLS	IRF5 ITGAX ADAM28 F13A1 CD163 CD163L1 UPK3A MSR1 LYZ	5.69e-05	237	188	9	M40264
Coexpression	CAIRO_LIVER_DEVELOPMENT_DN	KNTC1 HGFAC GAMT GCDH F12 HPN FGB FN1 LYZ	6.07e-05	239	188	9	MM1274
Coexpression	HOLLERN_EMT_BREAST_TUMOR_UP	GAMT F13A1 SACS MRC2 HSPG2 FN1 GZMH	7.03e-05	140	188	7	M617
Coexpression	NABA_ECM_GLYCOPROTEINS	VWA5B2 THSD4 FGB DMBT1 FN1 LAMA2 EGFEM1P AGRN	7.48e-05	191	188	8	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	VWA5B2 THSD4 FGB DMBT1 LAMB4 FN1 LAMA2 AGRN	8.96e-05	196	188	8	M3008
Coexpression	DELYS_THYROID_CANCER_UP	PRSS2 KLK10 BIRC7 ST14 RYR1 MRC2 HPN PLAU FN1 SLC6A1 MSR1 AGRN	9.56e-05	445	188	12	M3645
Coexpression	GSE15750_WT_VS_TRAF6KO_DAY10_EFF_CD8_TCELL_DN	KNTC1 RS1 SEMA5B SDK1 NAT14 PKHD1L1 SOX13 EGR4	1.03e-04	200	188	8	M3575
Coexpression	GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_DN	INPP5B ACSS1 ADAM8 RS1 SEMA5B GNRH1 PADI1 PNMT	1.03e-04	200	188	8	M8206
Coexpression	YOSHIMURA_MAPK8_TARGETS_UP	PRSS1 SLC6A17 CTRC TSHR ITPR1 JAG2 STRN PTPRH FGB HSD3B1 DNAH9 GNRH1 KCNT1 PADI1 DEAF1 SOX13 CRYBB2 EEF2 EGR4 GZMH USP40 LYZ	1.38e-04	1281	188	22	M1884
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN	KLK10 TBC1D2B LTB4R2 F13A1 ITPR1 DICER1 ARID2	1.44e-04	157	188	7	M7733
Coexpression	MARTENS_TRETINOIN_RESPONSE_UP	HGFAC KLK10 SLC6A17 BIRC7 RNF215 JAG2 TPSG1 MN1 KCNT1 CA4 SLC6A18 KLK12 LPIN3 SYT8 GZMH SUN5 SHISA3	1.53e-04	855	188	17	M2098
Coexpression	NABA_CORE_MATRISOME	VWA5B2 THSD4 FGB DMBT1 HSPG2 FN1 LAMA2 EGFEM1P AGRN	1.53e-04	270	188	9	MM17057
ToppCell	droplet-Pancreas-Exocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 GAMT TMPRSS13 CELA2A CTRC DMBT1 FN1 PNMT	3.83e-08	165	189	9	c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCell	TCGA-Pancreas\|World / Sample_Type by Project: Shred V9	PRSS1 PRSS2 CELA2A CTRC ADAM28 PTPRH PADI1 CELA2B SYT8	4.48e-08	168	189	9	279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWA5B2 THSD1 RNF215 JAG2 PLAU CA4 DNHD1 RGS12 ELP4	4.71e-08	169	189	9	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 GAMT CELA2A CTRC HPN PPP1R1B DMBT1 AGRN	1.12e-07	187	189	9	9aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DISC1 SLC22A23 PACSIN3 RS1 DHH PPP1R1B PLP1 SLC6A1 HPS6	1.17e-07	188	189	9	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ADAM28 F13A1 CD163 FCGBP MRC2 PLAU FN1 MSR1 LYZ	1.28e-07	190	189	9	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DISC1 ADAM28 PRSS36 F13A1 CD163 RYR1 CD163L1 SEMA4A MSR1	1.28e-07	190	189	9	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 LRRC32 JAG2 DHH MN1 HSPG2 FN1 DLL4 SLC14A1	1.47e-07	193	189	9	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	facs-Pancreas-Exocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 CELA2A CTRC HPN PPP1R1B DMBT1 HSPG2 AGRN	1.47e-07	193	189	9	c3161a14a40323a58aa202c8a1d6ea0e9c2b9814
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRF5 ITGAX CD163 CELA2B OVCH1 MSR1 RASGRP1 PSMD14	1.47e-07	139	189	8	505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	THSD4 TCTN3 ACTR5 MRM2 LAG3 RASGRP1 MEIOC TOP2B	2.15e-07	146	189	8	159dd157a74f3c27dc1a1dcbbf0ed8f9462cac9e
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 GAMT TMPRSS13 CELA2A CTRC DMBT1 PNMT	4.75e-07	162	189	8	922ecea81063095b8dd9ac9f9792bf551edbb848
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS13 PRSS22 ADAM8 ADAM28 FCGBP PTPRH UPK3A ISLR2	8.17e-07	174	189	8	76310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GAMT CELA2A CTRC HPN PPP1R1B DMBT1 AGRN	8.53e-07	175	189	8	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GAMT CELA2A CTRC FCGBP HPN PPP1R1B DMBT1	8.53e-07	175	189	8	7329ebb135fc4311ee9595729b62a5d152c9de8c
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS1 PRSS2 FCGBP HPN FGB KLK12 ITLN2 LYZ	9.29e-07	177	189	8	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	Club_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KLK10 PRSS22 ADAM28 FCGBP DMBT1 SDK1 KLK12 SLC6A1	9.69e-07	178	189	8	be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GAMT CELA2A CTRC HPN PPP1R1B DMBT1 AGRN	1.01e-06	179	189	8	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL12RB1 FAXC F13A1 CD163 MRM2 ISLR2 FCRL6 LPIN3	1.05e-06	180	189	8	1bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL12RB1 FAXC F13A1 CD163 MRM2 ISLR2 FCRL6 LPIN3	1.05e-06	180	189	8	2a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCell	facs-Pancreas-Exocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CELA2A CTRC FCGBP HPN PPP1R1B DMBT1 FN1	1.05e-06	180	189	8	72310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL12RB1 FAXC F13A1 CD163 MRM2 ISLR2 FCRL6 LPIN3	1.05e-06	180	189	8	12f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC TMPRSS13 ITPR1 FCGBP SUN2 HPN TPSG1 PLP1	1.05e-06	180	189	8	a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC PRSS2 TMPRSS13 CELA2A ITPR1 FCGBP HPN TPSG1	1.10e-06	181	189	8	75340f0c06977c88f9d2e56265f4aa84d706d2c6
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THSD4 MRC2 FLNA NAT14 FN1 LAMA2 ARSG ROBO2	1.10e-06	181	189	8	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	facs-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GAMT CELA2A CTRC HPN PPP1R1B DMBT1 AGRN	1.15e-06	182	189	8	45faefd7cbeac84d2c58650530b902af6ce921f8
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGAX ADAM28 F13A1 CD163 CD163L1 KIF25-AS1 MSR1 LYZ	1.15e-06	182	189	8	ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC6A17 ITGAX CD163 TYR PLAU UPK3A CRYBB2 LYZ	1.19e-06	183	189	8	745271bfe15e94a58157cd97d771e610f964341b
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 SEMA4A MSR1	1.46e-06	188	189	8	3be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 DHH MN1 HSPG2 FN1 DLL4 OVCH1 SOX13	1.52e-06	189	189	8	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 JAG2 DHH FGF2 MN1 HSPG2 FN1 DLL4	1.58e-06	190	189	8	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 JAG2 DHH MN1 HSPG2 FN1 DLL4 SLC14A1	1.64e-06	191	189	8	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	Control-Myeloid\|Control / group, cell type (main and fine annotations)	DISC1 ITGAX F13A1 CD163 CD163L1 OVCH1 MSR1 LYZ	1.64e-06	191	189	8	9c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLK10 LRRC32 JAG2 DHH ISLR2 FN1 DLL4 SOX13	1.64e-06	191	189	8	b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1	1.71e-06	192	189	8	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1	1.71e-06	192	189	8	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1	1.78e-06	193	189	8	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 LRRC32 CD163L1 SELE HSPG2 ISLR2 FN1 OVCH1	1.78e-06	193	189	8	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 JAG2 DHH FGF2 HSPG2 FN1 DLL4 SLC14A1	1.78e-06	193	189	8	6a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1 LYZ	1.85e-06	194	189	8	abce1e824ce2512741c313a5ec336d12f580b093
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1 LYZ	1.85e-06	194	189	8	6810586080cc893e3270b9c8bee2d95ed78e2893
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1	1.85e-06	194	189	8	0866ab6792cee274a71991d5c37a37f574ff446e
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DISC1 ITGAX ADAM28 F13A1 CD163 CD163L1 PLAU MSR1	1.85e-06	194	189	8	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 JAG2 DHH MN1 HSPG2 FN1 DLL4 SLC14A1	1.85e-06	194	189	8	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LRRC32 THSD1 JAG2 DHH HSPG2 DLL4 SOX13 AGRN	1.92e-06	195	189	8	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 MSR1 LYZ	1.92e-06	195	189	8	09df40ff9b493170861b3f6e57a942a834655b5c
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAM8 TBCC FCRL6 RASGRP1 SLC14A1 LYG1	1.93e-06	87	189	6	f92e08c2d1c2f216063ecfd42b06652e558c1a89
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC6A17 LRRC32 PTGIR CA4 FN1 LAMA2 SLC6A1 AGRN	1.99e-06	196	189	8	12d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 LYZ	1.99e-06	196	189	8	4370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 LRRC32 JAG2 DHH HSPG2 FN1 DLL4 SLC14A1	1.99e-06	196	189	8	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CELA2A ADAM28 ST14 F13A1 CD163 PLAU SEMA4A LYZ	2.07e-06	197	189	8	61bda9b5102fdbce902bb976d1aa62f2c799d2fb
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DISC1 ITGAX ADAM28 F13A1 CD163 CD163L1 PLAU MSR1	2.07e-06	197	189	8	e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell	T_cells-CTLs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ADAM8 SUN2 FLNA GNPTAB LAG3 FCRL6 RASGRP1 GZMH	2.07e-06	197	189	8	2de34e20915a247bee75aa40495e23c20bb23e18
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 LYZ	2.15e-06	198	189	8	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	control-cDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IRF5 ITGAX ADAM28 ST14 RYR1 UPK3A SEMA4A LYZ	2.23e-06	199	189	8	31825ba336603fe940dea6022e18ec25af110f4c
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD4+_CTL\|Leuk-UTI / Disease, condition lineage and cell class	PACSIN3 ZKSCAN7 JAG2 LAMA2 SOX13 FCRL6 RASGRP1 GZMH	2.23e-06	199	189	8	b2609f9d716fdd04f35f0da7f8995d28d7df431d
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 LRRC32 JAG2 DHH FGF2 HSPG2 FN1 DLL4	2.23e-06	199	189	8	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DISC1 ADAM28 F13A1 CD163 RYR1 CD163L1 PLAU MSR1	2.32e-06	200	189	8	179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DISC1 ITGAX ADAM28 F13A1 CD163 RYR1 CD163L1 MSR1	2.32e-06	200	189	8	ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intravascular\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ITGAX ADAM28 F13A1 CD163 CD163L1 PLAU MSR1 LYZ	2.32e-06	200	189	8	4b4df0fe47498310d94448b8a289e58e4f5b5aa8
ToppCell	Sigmoid-Macrophage-Macrophage\|Sigmoid / Region, Cell class and subclass	ITGAX ST14 F13A1 CD163 CD163L1 PLAU MSR1 LYZ	2.32e-06	200	189	8	9ee3a799de7bade1bfe94b6827461633f02bc1dc
ToppCell	Sigmoid-(6)_Macrophage-(60)_Macrophage\|Sigmoid / shred on region, Cell_type, and subtype	ITGAX ST14 F13A1 CD163 CD163L1 PLAU MSR1 LYZ	2.32e-06	200	189	8	ad84a83a5a1893f7b053d39eddeca851463a8ff0
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	FCGBP FLNA GNPTAB LAG3 LAMA2 FCRL6 RASGRP1 GZMH	2.32e-06	200	189	8	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	mild-cDC\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TCTN3 ITGAX ADAM28 ST14 RYR1 UPK3A SEMA4A LYZ	2.32e-06	200	189	8	d6409ee5b9067be3dd2f852825e09151b5b22d7c
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	THSD4 PTGIR FGF2 LAG3 ADAMTSL5 POLR1E HERC4	2.43e-06	141	189	7	a32947b13e888850c979a54c137512e4b96d2f36
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	THSD4 PTGIR FGF2 LAG3 ADAMTSL5 POLR1E HERC4	2.43e-06	141	189	7	2cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCell	E16.5-samps-Myeloid-Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	IRF5 TSHR CEND1 F13A1 CD163 SEMA4A DNAH9	3.35e-06	148	189	7	cd5f697d8c2f272be1f3f52a05446749278431c5
ToppCell	E16.5-samps-Myeloid-Macrophage-CD163+_Macrophage\|E16.5-samps / Age Group, Lineage, Cell class and subclass	IRF5 TSHR CEND1 F13A1 CD163 SEMA4A DNAH9	3.35e-06	148	189	7	56e146980a71b5ca655118ae13310c5949220d4a
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 GAMT CELA2A CTRC DMBT1 PNMT	4.17e-06	153	189	7	39ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	SLC22A23 CD163 MRC2 CD163L1 PLAU MSR1 LPIN3	4.74e-06	156	189	7	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	facs-MAT-Fat-24m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 CELA2A PRSS22 FGB UPK3A CRYBB2 SYT8	4.74e-06	156	189	7	7433c6d4eb4d061844d8979c1e648d8ed56e1073
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IL12RB1 BIRC7 ITGAX F13A1 CD163 FCGBP LYZ	5.60e-06	160	189	7	7f1b58641ba149d20420fafad34ba78a65a2c701
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 ADAM8 ITGAX F13A1 CD163 RYR1 MSR1	5.84e-06	161	189	7	3db97af49520dc8cbafb4454d8afd9d588160e89
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 ADAM8 ITGAX F13A1 CD163 RYR1 MSR1	5.84e-06	161	189	7	f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF5 ADAM8 ITGAX F13A1 CD163 RYR1 MSR1	5.84e-06	161	189	7	787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AGO2 SLC22A23 GNRH1 FN1 GNPTAB SLC14A1 LRBA	6.08e-06	162	189	7	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS1 PRSS2 GAMT CELA2A CTRC DMBT1	6.11e-06	106	189	6	3aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intermediate_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	ITGAX F13A1 CD163 PLAU MN1 MSR1 LYZ	6.86e-06	165	189	7	c3fa9225d2f9c9e821d4fbd2315fcc98ce1f1c55
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 SLC6A17 SLC22A23 PHKB STRN MEIOC ROBO2	7.13e-06	166	189	7	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 JAG2 UPK3A MN1 HSPG2 CRYBB2 SLC14A1	7.13e-06	166	189	7	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 SLC6A17 SLC22A23 PHKB STRN MEIOC ROBO2	7.13e-06	166	189	7	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 TENM2 F13A1 CD163 FCGBP CD163L1 MSR1	8.33e-06	170	189	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|390C / Donor, Lineage, Cell class and subclass (all cells)	FAXC ITGAX F13A1 CD163 FGF2 PLAU MSR1	8.33e-06	170	189	7	439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	IL12RB1 ITGA2B ISLR2 FN1 DLL4 PKHD1L1 HERC5	8.99e-06	172	189	7	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PSMA2 LRRC32 JAG2 DHH HSPG2 DLL4 SOX13	8.99e-06	172	189	7	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GAMT LRRC32 FAXC ITGA2B JAG2 GNRH1 SYT8	1.01e-05	175	189	7	36cb3c8116bd467ee5da0630d8b3d3e4afcc2ded
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 IL12RB1 PRSS2 CELA2A CEND1 CD163L1 RASGRP1	1.04e-05	176	189	7	feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCell	wk_20-22-Hematologic-Myeloid-pre-pDC/DC5\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CTRC IRF5 LTB4R2 ST14 UPK3A SEMA4A LYZ	1.08e-05	177	189	7	6de3c623f8595d7e3827df99b806bc9f1f15b3b7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRSS36 F13A1 CD163 RYR1 CD163L1 KIF25-AS1 MSR1	1.12e-05	178	189	7	4f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TPO JAG2 DHH HSPG2 FN1 DLL4 SLC14A1	1.12e-05	178	189	7	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRSS36 F13A1 CD163 RYR1 CD163L1 KIF25-AS1 MSR1	1.12e-05	178	189	7	24e8c62060455159235985f456af0c5023a7f3f5
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC TMPRSS13 CELA2A ITPR1 FCGBP HPN TPSG1	1.12e-05	178	189	7	07d6d5275a4d17f8024fde74e92ab2505b4adfbf
ToppCell	Healthy_Control-Lymphoid-T-NK\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	PRSS2 CEND1 JAK3 SCART1 FCRL6 RASGRP1 GZMH	1.17e-05	179	189	7	4cd0bb3a99f85ff599b4b79a6a9ace3e51f8b296
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS2 HPN PPP1R1B DMBT1 KLK12 ITLN2 LYZ	1.17e-05	179	189	7	6405010e8136a4d9bab356f628e36e3194911112
ToppCell	facs-Spleen-nan-3m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSS1 SUN2 FGB PLP1 RASGRP1 EEF2 TOP2B	1.21e-05	180	189	7	87fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC6A17 THSD1 JAG2 SELE HSPG2 LAMB4 DLL4	1.25e-05	181	189	7	7d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC32 ITPR1 JAG2 DHH HSPG2 DLL4 SOX13	1.25e-05	181	189	7	0ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ST14 FCGBP FGB UPK3A DMBT1 PADI1	1.25e-05	181	189	7	3fd16229a63de0971db5d48860c01173d7db518f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GAMT CELA2A CTRC HPN PPP1R1B DMBT1	1.25e-05	181	189	7	cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRSS2 GAMT CELA2A CTRC HPN PPP1R1B DMBT1	1.30e-05	182	189	7	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
Computational	Serine proteases.	PRSS2 KLK10 CELA2A CTRC F12 HPN PLAU CELA2B GZMH	2.73e-10	39	118	9	MODULE_109
Computational	Neighborhood of SERPINI2	PRSS1 PRSS2 CELA2A CTRC CELA2B	6.53e-06	25	118	5	GNF2_SERPINI2
Computational	Neighborhood of SPINK1	PRSS1 PRSS2 CELA2A CTRC	1.99e-04	27	118	4	GNF2_SPINK1
Computational	Genes in the cancer module 107.	PRSS2 KLK10 ADAM8 F12 HPN PLAU	2.23e-04	79	118	6	MODULE_107
Computational	Catabolic peptidases.	PRSS2 KLK10 F12 HPN PLAU LYZ	4.26e-04	89	118	6	MODULE_209
Computational	Blood coagulation factors.	F12 F13A1 FGB PLAU	4.42e-04	33	118	4	MODULE_131
Computational	Genes in the cancer module 172.	PRSS2 KLK10 F12 HPN PLAU LYZ	6.39e-04	96	118	6	MODULE_172
Drug	benzamidine	HGFAC PRSS1 PRSS2 TMPRSS13 CTRC ITGA2B ST14 F12 TYR HPN PRSS21 FGB PLAU TPSG1 KLK12	1.36e-12	147	187	15	CID000002332
Drug	EACA	HGFAC PRSS1 PRSS2 KLK10 CTRC ST14 F12 F13A1 EFTUD2 FGB PLAU KLK5 FN1 KLK12	2.88e-11	151	187	14	CID000000564
Drug	diisopropylfluorophosphate	HGFAC PRSS1 PRSS2 KLK10 CELA2A PRSS22 CTRC ST14 PRSS36 F12 HPN FGB PLAU KLK5 TPSG1 KLK12 GZMH	1.44e-09	321	187	17	CID000005936
Drug	1oz0	TSHR ADAM8 ITGAX F13A1 CD163 PLAU MSR1 HERC5	6.03e-09	49	187	8	CID006323417
Drug	Gly-pro-arg	PRSS1 PRSS2 ITGAX F13A1 FGB KLK5 FN1	6.37e-09	32	187	7	CID000170776
Drug	LMWH	PRSS1 PRSS2 KLK10 CTRC ITGA2B PTGIR F12 RYR1 ITPR1 FGB FGF2 PLAU KLK5 SELE HSPG2 LAMB4 FN1 LAMA2 KLK12 ADAMTSL5 LRBA AGRN	3.02e-08	663	187	22	CID000000772
Drug	phenylmethylsulfonyl fluoride	ERVK-6 PRSS1 PRSS2 KLK10 CTRC ST14 F12 TYR FGB PLAU KLK5 FN1 KLK12 GZMH	4.01e-08	263	187	14	CID000004784
Drug	camostate	PRSS1 PRSS2 KLK10 CTRC ST14 F12 PLAU KLK5 KLK12	4.58e-08	88	187	9	CID000002536
Drug	Leupeptin hydrochloride	PRSS1 PRSS2 KLK10 CTRC ST14 F12 MRC2 HPN PRSS21 PLAU KLK5 TPSG1 FN1 KLK12	7.31e-08	276	187	14	CID000003910
Drug	FPRck	PRSS1 PRSS2 ITGA2B FGF2 PLAU EEF2	1.43e-07	30	187	6	CID000115185
Drug	3,5-bis-trifluoromethylphenylboronic acid	PRSS1 PRSS2 CTRC LRBA	3.01e-07	8	187	4	CID000156265
Drug	sulfate	HGFAC PRSS1 PRSS2 CTRC THSD1 ST14 F12 TYR SSC4D DHH SEMA5B CIAO1 FGF2 TBCC CA4 SELE MRM2 HSPG2 LAMB4 FN1 LAMA2 CPOX ARSG MSR1 GBA3 ADAMTSL5 ROBO2 LYZ AGRN	7.95e-07	1292	187	29	CID000001117
Drug	NPGB	PRSS1 PRSS2 CTRC F12 TYR PLAU	1.00e-06	41	187	6	CID000030744
Drug	bumetanide	ERVK-6 PRSS1 PRSS2 KLK10 INPP5K RYR1 KLK5 CA4 KLK12 SLC6A1 SLC14A1	1.33e-06	209	187	11	CID000002471
Drug	Gly-pro-arg-pro	ITGA2B ITGAX F13A1 FGB PLAU FN1	1.34e-06	43	187	6	CID000123681
Drug	6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine	PRSS1 HPN PLAU	2.17e-06	4	187	3	DB03865
Drug	tricine	PRSS1 PRSS2 ITGA2B F13A1 GBA3 LYZ	2.30e-06	47	187	6	CID000079784
Drug	desogestrel	KLK10 F12 F13A1 FGB PLAU KLK5 GNRH1 KLK12	2.71e-06	106	187	8	CID000040973
Drug	dithiotreitol	TPO PRSS1 PRSS2 CTRC F13A1 RYR1 TYR JAK3 GNRH1 PADI1 LAMB4 LAMA2 CPOX LYZ TOP2B	2.91e-06	430	187	15	CID000019001
Drug	Z-Lys-OH	PRSS1 PRSS2 ST14 PLAU GZMH	2.99e-06	28	187	5	CID000075172
Drug	maltos	PRSS1 PRSS2 GAMT ITGAX AGL FGB PADI1 SELE LAMB4 LAMA2 ITLN2 GBA3 LRBA LYZ	4.95e-06	393	187	14	CID000000294
Drug	enterocin	PRSS1 PRSS2 GBA3 LYZ PSMD14	5.06e-06	31	187	5	CID000115182
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A	IRF5 ITPR1 MRC2 FGF2 SEMA4A HSPG2 FN1 CNTNAP1 RGS12 HERC4	5.12e-06	195	187	10	2805_UP
Drug	Ag-B	PRSS1 PRSS2 PLAU	5.39e-06	5	187	3	CID000004286
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; HL60; HG-U133A	THSD1 ADAM8 JAG2 MAGED2 SEMA4A RGS12 MTMR4 EGR4 TRAPPC10 AGRN	5.61e-06	197	187	10	1774_UP
Drug	Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; HL60; HG-U133A	IL12RB1 CTRC BIRC7 ITGA2B MRC2 PLCL2 PADI1 PNMT LAMA2 RGS12	5.86e-06	198	187	10	2042_UP
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	IL12RB1 INPP5B TBC1D2B SBF1 SEMA4A KLK5 DEAF1 FN1 RGS12 TAF15	6.41e-06	200	187	10	6829_DN
Drug	polybrene	PRSS1 PRSS2 F12 PHKB FN1 LYZ	7.26e-06	57	187	6	CID000024769
Drug	methyl acetimidate	PRSS1 PRSS2 INPP5K PNMT	9.65e-06	17	187	4	CID000026888
Drug	gamma-CDs	GCDH TYR AGL FN1	9.65e-06	17	187	4	CID000453205
Drug	kinin 9	PRSS1 PRSS2 KLK10 DISC1 PTGIR F12 ITPR1 FGB PLAU KLK5 GNRH1 KLK12 SLC14A2	1.03e-05	363	187	13	CID000006026
Drug	N-benzoyltyrosine butylamide	PRSS1 PRSS2 CTRC	1.07e-05	6	187	3	CID000125261
Drug	N-benzoyl-L-tyrosine thiobenzyl ester	PRSS1 PRSS2 CTRC	1.07e-05	6	187	3	CID000191444
Drug	N,N-dimethylglycylbenzocaine	PRSS1 PRSS2 CTRC	1.07e-05	6	187	3	CID000188251
Drug	2-azidoatrazine	PRSS1 PRSS2 CTRC	1.07e-05	6	187	3	CID003032432
Drug	1 PI	PRSS1 PRSS2 CTRC GCDH LYZ	1.09e-05	36	187	5	CID005287454
Drug	DB04780	KLK10 THSD1 F12 KLK5 PLP1 SELE FN1 KLK12 ARSG	1.19e-05	170	187	9	CID005459389
Drug	BAEE	PRSS1 PRSS2 CTRC F12 FGB TPSG1	1.43e-05	64	187	6	CID000123880
Drug	CHCl	PRSS1 PRSS2 KLK10 CTRC KLK5 KLK12	1.56e-05	65	187	6	CID006432229
Drug	EDTA	PRSS1 PRSS2 ITGA2B F13A1 CD163 FGB DICER1 LYZ	1.62e-05	135	187	8	CID000006049
Drug	isocoumarin	PRSS1 PRSS2 F12 TPSG1 GZMH	1.63e-05	39	187	5	CID000068108
Drug	S 2251	PRSS1 PRSS2 F12 FGB PLAU	1.85e-05	40	187	5	CID000124997
Drug	thiocyanuric acid	TYR TPSG1 LYZ	1.86e-05	7	187	3	CID001268121
Drug	pentaammineaquocobalt(III) tetrafluoroborate	PRSS1 PRSS2 CTRC	1.86e-05	7	187	3	CID000412963
Drug	bz-Ar	PRSS1 PRSS2 FN1	1.86e-05	7	187	3	CID000137302
Drug	Cbz-phe-arg-chn2	PRSS1 PRSS2 CTRC	1.86e-05	7	187	3	CID005492392
Drug	N-bromosuccinimide	PRSS1 PRSS2 CTRC GBA3 EEF2 LYZ	2.21e-05	69	187	6	CID000067184
Drug	Grgdspk	CTRC ITGA2B TPSG1 FN1	2.36e-05	21	187	4	CID000130667
Drug	2-aminopyridine	KNTC1 PRSS1 PRSS2 F12 FGB PLAU	2.40e-05	70	187	6	CID000010439
Drug	AC1L2Q8B	PRSS1 PRSS2 CTRC ST14	2.87e-05	22	187	4	CID000126377
Drug	AC1MCHYW	PRSS1 PRSS2 CTRC	2.96e-05	8	187	3	CID002770087
Drug	Bio-Phe-CH2Cl	PRSS1 PRSS2 CTRC	2.96e-05	8	187	3	CID000083924
Drug	Bio-Arg-CH2Cl	PRSS1 PRSS2 CTRC	2.96e-05	8	187	3	CID000083923
Drug	harderoporphyrin	PRSS1 PRSS2 CPOX	2.96e-05	8	187	3	CID003081462
Drug	Boc hydrazine	PRSS1 PRSS2 GBA3	2.96e-05	8	187	3	CID000070091
Drug	Benzamidine	PRSS1 ST14 PLAU	2.96e-05	8	187	3	DB03127
Drug	Rgd Peptide	GCDH ITGA2B THSD1 ITGAX FGB FGF2 PLAU LAMB4 FN1 ADAMTSL5	3.00e-05	239	187	10	CID000104802
Drug	theophylline	ERVK-6 KLK10 HDAC8 LTB4R2 PTGIR TYR KLK5 KLK12 CPOX GBA3	3.22e-05	241	187	10	CID000002153
Drug	Alsterpaullone; Up 200; 10uM; MCF7; HT_HG-U133A	GAMT CTRC SBF1 MRC2 MN1 PADI1 FN1 GNPTAB AGRN	3.38e-05	194	187	9	7051_UP
Drug	Meptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A	GAMT INPP5B DISC1 SBF1 PLCL2 TPSG1 PADI1 SOX13 DICER1	3.52e-05	195	187	9	7326_UP
Drug	Ganciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A	DISC1 ADAM8 F13A1 MRC2 PLCL2 TPSG1 HSPG2 LAMB4 MSR1	3.67e-05	196	187	9	3368_UP
Drug	S(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	GAMT INPP5K THSD1 STRN SBF1 KLK5 MSANTD2 SOX13 RGS12	3.82e-05	197	187	9	5400_DN
Drug	Fosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A	CTRC BIRC7 ITGA2B RYR1 PTPRH HPN SEMA4A GNPTAB MSR1	3.82e-05	197	187	9	4239_UP
Drug	Acetaminophen [103-90-2]; Up 200; 26.4uM; MCF7; HT_HG-U133A	TSHR CEND1 ITGA2B PLCL2 PLAU PLP1 LAMB4 GNPTAB RGS12	3.82e-05	197	187	9	3364_UP
Drug	Monocrotaline [315-22-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	GAMT ACTR5 INPP5B DISC1 INPP5K THSD1 MAP4K5 LRBA HERC4	3.82e-05	197	187	9	6771_DN
Drug	chondroitin sulfate	PRSS1 PRSS2 PSMA2 THSD1 SEMA5B FGF2 HSPG2 FN1 LAG3 ARSG ADAMTSL5 LYZ AGRN	3.96e-05	413	187	13	CID000024766
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; MCF7; HT_HG-U133A	DISC1 INPP5K ST14 SBF1 SEMA4A KLK5 CA4 DEAF1 RGS12	3.97e-05	198	187	9	3261_DN
Drug	Mesoridazine besylate [32672-69-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A	THSD4 INPP5B IRF5 STRN MAGED2 PADI1 FN1 LAMA2 MSR1	3.97e-05	198	187	9	7017_UP
Drug	Betamethasone-d5	TPO IL12RB1 PRSS1 PRSS2 KLK10 CTRC ITGA2B LTB4R2 ITGAX PTGIR CD163 ITPR1 FGB FGF2 PLAU KLK5 GNRH1 SELE LAMB4 FN1 PNMT LAMA2 KLK12 SOX13 LRBA LYZ	4.00e-05	1340	187	26	CID000003003
Drug	S-2648	PRSS1 PRSS2 F12 FGB PLAU	4.11e-05	47	187	5	CID000123687
Drug	L-Asp-Gly	ITGAX FGF2 FN1 LYZ	4.12e-05	24	187	4	CID000151148
Drug	nafamostat mesilate	PRSS1 PRSS2 ITGA2B F12 FGB TPSG1	4.14e-05	77	187	6	CID000004413
Drug	OP-2507	TPO PTGIR SELE	4.42e-05	9	187	3	CID006438365
Drug	FK-401	PRSS1 PRSS2 CTRC	4.42e-05	9	187	3	CID000135041
Drug	xemilofiban	ITGA2B FGB FN1	4.42e-05	9	187	3	CID000060957
Drug	glyphosate	SLC22A23 ACSS1 ITPR1 PHKB SACS FGB HSD3B1 SLC6A1 EEF2 SCAP CCZ1 LYZ HERC4 HERC5	4.47e-05	479	187	14	ctd:C010974
Drug	C4 m	PRSS1 PRSS2 CTRC ITGA2B FGB PLAU	4.79e-05	79	187	6	CID009543487
Drug	1-piperidinocyclohexanecarbonitrile	TPO GBA3 ROBO2 LRBA	4.87e-05	25	187	4	CID000062529
Drug	TLCK	PRSS1 PRSS2 KLK10 CTRC FGB KLK5 TPSG1 KLK12	5.02e-05	158	187	8	CID000004427
Drug	Opgan	PRSS1 PRSS2 F12 PLAU	5.72e-05	26	187	4	CID000121898
Drug	L-lysyl-L-lysyl-L-lysine	PRSS1 PRSS2 KLK10 KLK5 SELE FN1 KLK12 LYZ	6.00e-05	162	187	8	CID000072363
Drug	AC1NUP69	PRSS1 PRSS2 TPSG1	6.27e-05	10	187	3	CID005487154
Drug	RD4-6205	PRSS1 PRSS2 CTRC	6.27e-05	10	187	3	CID003002865
Drug	TAPAP	PRSS1 PRSS2 PLAU	6.27e-05	10	187	3	CID000126363
Drug	tert-butylcatechol	PRSS1 PRSS2 TYR	6.27e-05	10	187	3	CID000077643
Drug	Grgds	ITGA2B THSD1 FGB FLNA FN1 LAG3	6.33e-05	83	187	6	CID000123811
Drug	histamine	KLK10 LTB4R2 ITGAX PTGIR F12 DHH KLK5 TPSG1 GNRH1 SELE PNMT KLK12 MUC12 CPOX LRBA	6.40e-05	560	187	15	CID000000774
Drug	Thieno[2,3-B]Pyridine-2-Carboxamidine	PRSS1 PLAU	6.71e-05	2	187	2	DB03876
Drug	CRA_10655	PRSS1 PLAU	6.71e-05	2	187	2	DB02526
Drug	farresol	TYR LYZ	6.71e-05	2	187	2	CID000091144
Drug	2-(2-Hydroxy-5-Methoxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine	PRSS1 PLAU	6.71e-05	2	187	2	DB01905
Drug	CHEBI:396442	GNRH1 PNMT	6.71e-05	2	187	2	CID011337569
Drug	AC1NUK2U	TYR LYZ	6.71e-05	2	187	2	CID000469121
Drug	CRA_1144	PRSS1 HPN	6.71e-05	2	187	2	DB03643
Drug	sulfonamide analog 1	PRSS1 PRSS2 INPP5K CTRC F13A1 PPP1R1B FGB PLAU LRBA	6.99e-05	213	187	9	CID005327336
Drug	DDAVP	ITGA2B ST14 F12 PLAU SLC14A1 HPS6 SLC14A2	7.18e-05	123	187	7	CID000027991
Drug	AC1Q6GKY	PRSS1 PRSS2 GNRH1 TBCC LYZ	7.39e-05	53	187	5	CID000002283
Drug	ABAP	TSHR ITGAX CD163 LYZ HERC5	7.39e-05	53	187	5	CID000001969
Drug	AC1LD8Z3	PRSS1 PRSS2 ITGA2B RYR1 DNAH9 EEF2	7.72e-05	86	187	6	CID000644309
Drug	Lb I	PRSS1 PRSS2 CTRC LRBA	7.73e-05	28	187	4	CID000161844
Disease	PANCREATITIS, HEREDITARY	PRSS1 PRSS2 CTRC	2.25e-06	5	181	3	167800
Disease	Hereditary pancreatitis	PRSS1 PRSS2 CTRC	2.25e-06	5	181	3	cv:C0238339
Disease	Autosomal Dominant Hereditary Pancreatitis	PRSS1 PRSS2 CTRC	2.25e-06	5	181	3	C4080064
Disease	Hereditary pancreatitis	PRSS1 PRSS2 CTRC	7.80e-06	7	181	3	C0238339
Disease	mitral valve prolapse (is_implicated_in)	TSHR PLAU FLNA	1.86e-05	9	181	3	DOID:988 (is_implicated_in)
Disease	Pancreatitis, Chronic	PRSS1 PRSS2 CTRC	1.86e-05	9	181	3	C0149521
Disease	retinoschisis (is_implicated_in)	RS1 TYR	3.74e-05	2	181	2	DOID:8465 (is_implicated_in)
Disease	tubulointerstitial nephritis antigen-like measurement	HSPG2 MAP4K5	1.12e-04	3	181	2	EFO_0803197
Disease	Acute recurrent pancreatitis	PRSS1 CTRC	2.23e-04	4	181	2	C0267937
Disease	Myxedema, Congenital	TPO TSHR	2.23e-04	4	181	2	C1578691
Disease	Endemic Cretinism	TPO TSHR	2.23e-04	4	181	2	C0342200
Disease	syntaxin-1a measurement	HGFAC RGS12	3.70e-04	5	181	2	EFO_0020759
Disease	kallikrein-7 measurement	CD163 CD163L1	3.70e-04	5	181	2	EFO_0008195
Disease	autosomal recessive limb-girdle muscular dystrophy (is_implicated_in)	JAG2 LAMA2	3.70e-04	5	181	2	DOID:0110274 (is_implicated_in)
Disease	L lactate dehydrogenase measurement	CD163 CD163L1 MAP4K5	5.32e-04	26	181	3	EFO_0004808
Disease	Congenital hypothyroidism	TPO TSHR	5.52e-04	6	181	2	cv:C0010308
Disease	kallikrein-8 measurement	KLK10 KLK5	5.52e-04	6	181	2	EFO_0020516
Disease	chloride measurement	HDAC8 ARSG MAP4K5	7.38e-04	29	181	3	EFO_0009284
Disease	hepatocyte growth factor activator measurement	HGFAC RGS12	7.70e-04	7	181	2	EFO_0008152
Disease	glycoprotein measurement	HGFAC F12 HPN FGB MAP4K5	8.54e-04	119	181	5	EFO_0004555
Disease	gamma-glutamyl hydrolase measurement	GNPTAB MAP4K5	1.02e-03	8	181	2	EFO_0801616
Disease	Schizophrenia	DISC1 CD163 JAG2 TYR PPP1R1B PLCL2 FGF2 PLP1 LAMA2 DICER1 RGS12 SLC6A1 EGR4 ERVK-8	1.15e-03	883	181	14	C0036341
Disease	refractive error, self reported educational attainment	LAMA2 ARID2 SLC14A2	1.18e-03	34	181	3	EFO_0004784, MONDO_0004892
Disease	renal cell carcinoma (is_marker_for)	ST14 FGF2 PLAU FN1 DLL4	1.18e-03	128	181	5	DOID:4450 (is_marker_for)
Disease	kallikrein-11 measurement	KLK10 KLK12	1.31e-03	9	181	2	EFO_0010573
Disease	cathepsin F measurement	GNPTAB MAP4K5	1.31e-03	9	181	2	EFO_0022038
Disease	Prostatic Neoplasms	ADAM28 ST14 ITPR1 HPN FGF2 PLAU HSD3B1 KLK5 MSR1 ARID2 ROBO2	1.55e-03	616	181	11	C0033578
Disease	Malignant neoplasm of prostate	ADAM28 ST14 ITPR1 HPN FGF2 PLAU HSD3B1 KLK5 MSR1 ARID2 ROBO2	1.55e-03	616	181	11	C0376358
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma	AGO2 MN1 ROBO2	1.76e-03	39	181	3	EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Disease	Inherited neuropathies	ITPR1 SACS PLP1	1.90e-03	40	181	3	C0598589
Disease	Internal Carotid Artery Diseases	CD163 PLAU	1.98e-03	11	181	2	C0750986
Disease	Arterial Diseases, Common Carotid	CD163 PLAU	1.98e-03	11	181	2	C0750987
Disease	Carotid Atherosclerosis	CD163 PLAU	1.98e-03	11	181	2	C0577631
Disease	Adrenal Gland Neoplasms	TSHR GNRH1	1.98e-03	11	181	2	C0001624
Disease	External Carotid Artery Diseases	CD163 PLAU	1.98e-03	11	181	2	C0600178
Disease	Carotid Artery Diseases	CD163 PLAU	1.98e-03	11	181	2	C0007273
Disease	Adrenal Cancer	TSHR GNRH1	1.98e-03	11	181	2	C0750887
Disease	Disorder of eye	TCTN3 RS1 TYR SEMA4A CA4 PCARE	2.03e-03	212	181	6	C0015397
Disease	Congenital muscular dystrophy	RYR1 LAMA2	2.37e-03	12	181	2	cv:C0699743
Disease	Thromboembolism	F12 PLAU	2.37e-03	12	181	2	C0040038
Disease	tRNA (guanine-N(7)-)-methyltransferase measurement	F12 MAP4K5	2.79e-03	13	181	2	EFO_0802162
Disease	Congenital Hypothyroidism	TPO TSHR	2.79e-03	13	181	2	C0010308
Disease	hypertension (biomarker_via_orthology)	HDAC8 FGF2 HSD3B1 HSPG2 FN1 PNMT	2.86e-03	227	181	6	DOID:10763 (biomarker_via_orthology)
Disease	alcoholic pancreatitis	PRSS1 PRSS2 CELA2A CTRC	3.16e-03	98	181	4	EFO_1002013
Disease	response to methotrexate, aspartate aminotransferase measurement	THSD4 NOL11	3.24e-03	14	181	2	EFO_0004736, GO_0031427
Disease	congenital hypothyroidism (implicated_via_orthology)	TPO TSHR	3.24e-03	14	181	2	DOID:0050328 (implicated_via_orthology)
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	3.24e-03	14	181	2	DOID:3753 (implicated_via_orthology)
Disease	myocardial infarction (is_implicated_in)	F12 F13A1 FGB PLAU	3.28e-03	99	181	4	DOID:5844 (is_implicated_in)
Disease	creatinine measurement	HGFAC ST14 F12 F13A1 RYR1 JAG2 LAMA2 FSD2 CELA2B RGS12 USP10 MAP4K5 SLC14A2 SHISA3	3.44e-03	995	181	14	EFO_0004518
Disease	cathepsin D measurement	GNPTAB MAP4K5	3.73e-03	15	181	2	EFO_0010611
Disease	Retinitis Pigmentosa	SEMA4A CA4 CCZ1B PCARE	3.91e-03	104	181	4	C0035334
Disease	alkaline phosphatase measurement	IRF5 ITPR1 PHKB HPN DMBT1 MLST8 SELE HSPG2 ARSG RPUSD4 MAP4K5 LRBA LYZ CNOT1	4.09e-03	1015	181	14	EFO_0004533
Disease	Spondyloepiphyseal Dysplasia	HSPG2 FLNA	4.24e-03	16	181	2	C0038015
Disease	vision disorder	TPO SDK1	4.24e-03	16	181	2	MONDO_0021084
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 FLNA	4.24e-03	16	181	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 FLNA	4.24e-03	16	181	2	C4551479
Disease	Huntington's disease (biomarker_via_orthology)	ITPR1 PPP1R1B	4.24e-03	16	181	2	DOID:12858 (biomarker_via_orthology)
Disease	Schwartz-Jampel Syndrome	HSPG2 FLNA	4.24e-03	16	181	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 FLNA	4.24e-03	16	181	2	C0025237
Disease	diabetic retinopathy (is_marker_for)	F13A1 FGF2 DLL4	4.48e-03	54	181	3	DOID:8947 (is_marker_for)
Disease	fibrinogen measurement	HGFAC PTGIR ITPR1 FGB	4.62e-03	109	181	4	EFO_0004623
Disease	Glycogen storage disease	PHKB AGL	4.79e-03	17	181	2	cv:C0017919
Disease	Van Buchem disease	HSPG2 FLNA	4.79e-03	17	181	2	C0432272
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	HGFAC FGB MAP4K5	4.96e-03	56	181	3	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	Myeloid Leukemia	AGO2 TOP2B	5.37e-03	18	181	2	C0023470
Disease	Leukemia, Monocytic, Chronic	AGO2 TOP2B	5.37e-03	18	181	2	C0023466
Disease	fibrinogen measurement, factor VII measurement	HGFAC FGB MAP4K5	5.47e-03	58	181	3	EFO_0004619, EFO_0004623
Disease	calcium measurement	HGFAC TBC1D2B RNF215 ITPR1 SEMA5B HPN DMBT1 RGS12 MAP4K5 USP40	5.60e-03	628	181	10	EFO_0004838
Disease	adverse effect, response to xenobiotic stimulus	ST14 SOX13 CRYBB2	5.74e-03	59	181	3	EFO_0009658, GO_0009410
Disease	concentration of chylomicrons and extremely large VLDL particles measurement	HGFAC MAP4K5 AGRN	5.74e-03	59	181	3	EFO_0022260
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNA	5.97e-03	19	181	2	DOID:2256 (is_implicated_in)
Disease	Osteochondrodysplasias	HSPG2 FLNA	5.97e-03	19	181	2	C0029422
Disease	Cholecystitis	MAP4K5 LRBA	5.97e-03	19	181	2	HP_0001082
Disease	sensorineural hearing loss (implicated_via_orthology)	DNAH9 DNAH17	5.97e-03	19	181	2	DOID:10003 (implicated_via_orthology)
Disease	renovascular hypertension (biomarker_via_orthology)	HDAC8 LAMA2	5.97e-03	19	181	2	DOID:1591 (biomarker_via_orthology)
Disease	glomerulonephritis (is_marker_for)	CD163 FN1	5.97e-03	19	181	2	DOID:2921 (is_marker_for)
Disease	Dyschondroplasias	HSPG2 FLNA	5.97e-03	19	181	2	C0013366
Disease	Brain Ischemia	IL12RB1 PLAU SELE	6.01e-03	60	181	3	C0007786
Disease	Cerebral Ischemia	IL12RB1 PLAU SELE	6.01e-03	60	181	3	C0917798

Protein segments in the cluster

Peptide	Gene	Start	Entry
CGPQAYRQLPAKWSG	ERV3-1	421	Q14264
PGYGCWLSGIDVSTQ	COPS5	141	Q92905
NFLPGCWLVGDVAGS	BRWD1-AS2	31	P59051
QPGDIFGCVADIGWI	ACSS1	326	Q9NUB1
QHFYWGGSQPGIQRC	CNTNAP1	701	P78357
AGPWVGYEQANCKGE	CRYBB2	56	P43320
GWNLKNGGTLYTCAL	HSD3B1	171	P14060
CGKLFCQGGSDNLPW	ADAM28	561	Q9UKQ2
CQGGSDNLPWKGRIV	ADAM28	566	Q9UKQ2
LIYGSDGPWCTQAGF	BAALC-AS2	86	P0C853
GPLGTCLAQVQWAGG	FAM220BP	6	B1ANY3
DNCAGFLWGVIKQGY	RASGRP1	556	O95267
VKPGQLCSVAGWGYV	GZMH	136	P20718
CEPGFWNFRGIVTDG	AGRN	826	O00468
EHGGKDVYPGQCLWE	ARID2	1656	Q68CP9
PWSCENFNPLLVAGG	CEND1	116	Q8N111
GWTGEYCQQPICLSG	DLL4	211	Q9NR61
FCYGGLQSWKRGDDP	BIRC7	126	Q96CA5
GDNGPWAQKCELAGS	ARSG	301	Q96EG1
DNGSFQVRAGWACPG	ACTR5	36	Q9H9F9
SGGPLNCQASDGRWQ	CELA2A	216	P08217
CLSNYLNGALQGGAW	DNHD1	1721	Q96M86
QAFWGPGGQAAEESC	ADAM8	516	P78325
PCSGTVEVKFQGQWG	CD163L1	56	Q9NR16
FGEGSGPIWLDDLNC	CD163L1	1091	Q9NR16
GFWNPSEENCGVDTG	DICER1	1526	Q9UPY3
CGPGSAGWQQEFAAM	DISC1	136	Q9NRI5
EGCSNPLGGGREVWF	AGO2	186	Q9UKV8
ASQELLPYLEGGCWG	ARHGEF39	76	Q8N4T4
YLCPAGGGAAVQWSR	ISLR2	531	Q6UXK2
LEQVFGQGGWDAQPC	MSANTD2	196	Q6P1R3
FQGRGGDPKSGDWVC	TAF15	346	Q92804
WGPEGYGAILLVNCD	PADI1	141	Q9ULC6
QGTYICQAHGPWGKA	HSPG2	3461	P98160
NLSWYNGTVNPCPGL	SPINK14	46	Q6IE38
CDAVLYGEQGHPWGR	ITGAX	506	P20702
GLWNGAQLYACQDPT	JAK3	801	P52333
NWETPQGCGLGFQNS	NOL11	361	Q9H8H0
SGGGPFSNLLRWVVC	FAXC	221	Q5TGI0
GYLQWVSEGGCSLPK	LPIN3	701	Q9BQK8
LPLCWTGDAGGNVNL	OR1B1	166	Q8NGR6
GLGSENAAGPCNWDE	MAGED2	506	Q9UNF1
QINSRYWCNDGKTPG	LYZ	76	P61626
QPWQFGGGINSVSYC	GNPTAB	491	Q3T906
VVQHDPCRGGAGYWN	ITPR1	286	Q14643
KIFNGTECGRNSQPW	KLK12	21	Q9UKR0
LPCYNGGICVDGVNW	JAG2	796	Q9Y219
ALGIGCWGCPKQNYS	KCNT1	121	Q5JUK3
EVCSHLYWRGAGQGP	PRSS22	206	Q9GZN4
GLYWCEVAPEGGQVQ	FCRL6	176	Q6DN72
TGNCYVWNLTGGIGD	MLST8	191	Q9BVC4
CGLPGEYWLGNDKIS	FGB	316	P02675
QAEGGWGCLGYTLVR	NAT14	186	Q8WUY8
HGLPGYNEWREFCGL	TPO	586	P07202
SEVFCWGQNKYGQLG	HERC4	156	Q5GLZ8
WGQNKYGQLGLGTDC	HERC4	161	Q5GLZ8
WGRGFACVSPGENQL	HERVK_113	831	P63132
WNGKCSGIGDNPGSE	LRBA	2671	P50851
NGSECWKKENGFPAG	LMLN2	491	A0A1B0GTW7
GSKRLQCGPTGEWDN	SELE	406	P16581
WNRDQPGYSRGGCVA	MRC2	606	Q9UBG0
QPGGCTYVDVDGAWR	MRC2	1216	Q9UBG0
SENPVRYGQCWVFAG	F13A1	306	P00488
IIGGTGNCAFSKWEP	KNTC1	221	P50748
VYDAGVPGHLCDGQW	LAMA2	3011	P24043
CNGSLQGLVSWGDYP	KLK5	251	Q9Y337
SGPWGCILTYRDGFN	LAG3	236	P18627
AQGGGPSATEWACIL	C6orf223	11	Q8N319
WELLSVGAPGNCGSQ	EGR4	311	Q05215
NSCQYPGLQWVNGEK	IRF5	26	Q13568
KGCSPAWGFLPQARG	KIF25-AS1	151	Q9Y6Z4
GSTFPAGHKCQIAGW	HGFAC	526	Q04756
PGVNGCQDTQGNWYD	MED26	561	O95402
WGRGFACVSPGENQL	ERVK-7	831	P63135
WGRGFACVSPGENQL	ERVK-6	831	Q9BXR3
WALLNCGLGVSAQGP	ADAMTSL5	31	Q6ZMM2
SWGTGCALAQKPGVY	HPN	376	P05981
GPCFGGQWAQREGVK	MTMR4	946	Q9NYA4
GQGTGPIWLNEVFCF	MSR1	406	P21757
FPQGIELFCQPSGWQ	SBF1	41	O95248
GPLVCDKDGLWYQVG	PRSS41	251	Q7RTY9
NIYSWGKNECGQLGL	HERC5	211	Q9UII4
LYLQGNPLSCCGNGW	LRRC32	566	Q14392
PLVCEEGGRWFQAGI	PRSS36	246	Q5K4E3
SGGPLNCQLENGSWE	CTRC	216	Q99895
SSNYPCLVPVKWGGN	CA4	31	P22748
SGGPLNCQASDGRWE	CELA2B	216	P08218
SCGNIYKGLAQTGAW	DNAH17	1881	Q9UFH2
PFGCLNNARYGIAWG	GCDH	286	Q92947
YQVEGGWDADGKGPC	GBA3	16	Q9H227
SGGRGRCIKQGENWY	DEAF1	221	O75398
AGGCFPGNATVRLWS	DHH	196	O43323
VPLNNGCGCWANGTY	FCGBP	2001	Q9Y6R7
GTECGNQKVRAWGPG	FLNA	571	P21333
GRGIGEWHCQPLQTY	FN1	591	P02751
GLFGYWGNKGGVNIC	INPP5K	121	Q9BT40
AGAGSGPWAAQEKQF	CCZ1	6	P86791
AGAGSGPWAAQEKQF	CCZ1B	6	P86790
TYCIEWQPVGQDGGL	IL12RB1	366	P42701
WQPVGQDGGLATCSL	IL12RB1	371	P42701
NWGCYGNIQSLDTPG	LYG1	21	Q8N1E2
YRSGKCWNDNGPAIP	ITLN2	206	Q8WWU7
QGKPRQCGDFSAFDW	ITLN2	286	Q8WWU7
KPGGVLTYCNLTSWG	GAMT	161	Q14353
WLSNGIQAPDVYCVG	INPP5B	366	P32019
ARGCNGIPGAAAWEA	FGF2	26	P09038
DGYWNLVPGRGCQSC	LAMB4	1066	A4D0S4
ARKIWCFGPDGTGPN	EEF2	646	P13639
GNIYKGLAQTGAWGC	DNAH9	1906	Q9NYC9
GIQNLGSPLWGDDIC	ELP4	256	Q96EB1
LGGGGYNLANTARCW	HDAC8	301	Q9BY41
CSSQHWSYGLRPGGK	GNRH1	21	P01148
QLTPGGTQRCWNLYG	DEFB123	16	Q8N688
LGLFCVGWEAPQGVE	HPS6	381	Q86YV9
EGSGPIWFDDLICNG	CD163	216	Q86VB7
CGWATSAPGNARFGQ	DMBT1	406	Q9UGM3
RQLGCGWATSAPGNA	DMBT1	641	Q9UGM3
CGWATSAPGNARFGQ	DMBT1	776	Q9UGM3
RQLGCGWATSAPGNA	DMBT1	901	Q9UGM3
QLGCGWATSAPGNAR	DMBT1	1291	Q9UGM3
LGCGWATSAPGNARF	DMBT1	1421	Q9UGM3
GYQGNRCQKDGLWGP	EGFEM1P	91	Q0D2K5
SWGEPAAANGILQGY	SDK1	1821	Q7Z5N4
TGGQGCVSFWDLNYG	SCAP	1216	Q12770
NYPGSLVWKGDLCNL	SACS	1166	Q9NZJ4
IGWNPCGGERYLDFL	RYR1	2321	P21817
WFGGGCDLTPTYLNQ	CPOX	276	P36551
PSNCGRDGKLFLWGQ	PHKB	431	Q93100
KNGGYNQLCDIWAVG	MAP4K5	191	Q9Y4K4
EAGGPLGNPAECWKN	PCARE	1151	A6NGG8
WCQGQLQSGRIGLYP	PACSIN3	401	Q9UKS6
PGFGCWLSGVDINTQ	PSMD14	116	O00487
FPGSAGVDRCASWNG	MN1	461	Q10571
WQYCGAPDGSQRAVL	POLR1E	11	Q9GZS1
WGSGCGDRNKPGVYT	F12	586	P00748
PWIRGNGQGCGSLFT	RPUSD4	11	Q96CM3
DGLESSPGDAQQWGC	SYT8	106	Q8NBV8
VAFPGGANRCWNLGA	MEIOC	26	A2RUB1
CYSGGTDGLIQGWNT	STRN	531	O43815
QAGTVSWGEGCGRPN	TPSG1	236	Q9NRR2
QWKTDSCQGDSGGPL	PLAU	366	P00749
GVCGKAFSRPWLLQG	SCRT1	251	Q9BWW7
NVWRFPYLCGKNGGG	SLC6A1	66	P30531
NELVENFGRCPKWSG	PPP4R1	826	Q8TF05
GIGTGWACKLPNYDA	TOP2B	876	Q02880
FLTRQAWPLGQAGCK	LTB4R2	81	Q9NPC1
LDQPNFWCRGAGKGT	SLC22A23	121	A1A5C7
GDYQCGGAIINPVWI	OVCH1	596	Q7RTY7
GWGSAGQCQDLREAY	FSD2	136	A1L4K1
GWFRQNGNCGYVLRP	PLCL2	716	Q9UPR0
DGVGGLYQCWATENG	SEMA4A	616	Q9H3S1
YGGWQDLVCLGGSRA	RNF215	231	Q9Y6U7
WGPAGAQQSGEYCHG	SHISA3	16	A0PJX4
SPGWGGLNCELARVQ	TENM2	691	Q9NT68
TGGVFLCPWRAEGGQ	ITGA2B	81	P08514
CTGFAVGLGNIWRFP	SLC6A18	31	Q96N87
WRQYLPGNEQGVACS	CIAO1	221	O76071
LEWGQKLPEFGVGFC	CLEC20A	91	Q6ZU45
QDGRAYGSPWCNKQI	CNOT1	1696	A5YKK6
NGVGPWKLRCLAQTF	PNMT	51	P11086
QGNFRGSWDCSSPEG	SOX13	66	Q9UN79
VTPGNCWAFEGDRGQ	SUN5	246	Q8TC36
CGARGPNDWNLNIYF	TSPAN17	156	Q96FV3
SGGPLVCEQNNRWYL	TMPRSS13	511	Q9BYE2
WGTGCGQRNKPGVYT	TMPRSS13	531	Q9BYE2
TVGAGCGFNQRWLPV	RGS12	526	O14924
CWAFQGPQGFAVVRL	SUN2	601	Q9UH99
GEPRLAACQSLGWGV	SSC4D	261	Q8WTU2
LGLGQHQQYCPGSWC	PTGIR	156	P43119
FAGNGGPDCAAFLSW	TMEM164	21	Q5U3C3
LAQGQWVEFGCAPLG	THSD1	196	Q9NS62
WGDGCAQRNKPGVYT	ST14	826	Q9Y5Y6
WGRGFACVSPGENQL	ERVK-10	831	P10266
WGRGFACVSPGENQL	ERVK-8	831	P63133
GNCKFGFWGPNCTER	TYR	101	P14679
VGANGTCLWDPNFQG	UPK3A	136	O75631
WGRGFACVSPGENQL	ERVK-11	831	Q9UQG0
GVSLLICGWNEGRPY	PSMA2	131	P25787
GSGPVWTEAFRCAGN	SCART1	286	Q4G0T1
VKQPAFIAGIGGACW	ROBO2	856	Q9HCK4
GDLGPSWVCGFSNLE	TBCC	176	Q15814
LGARDPYCGWDGKQQ	SEMA5B	566	Q9P283
SNGELQGIVSWGYGC	PRSS2	206	P07478
LINGPQDHGWCAGYT	PKHD1L1	3796	Q86WI1
GQIYGCDNPWTGGIF	SLC14A1	231	Q13336
QPGGTFLCKTWAGSQ	MRM2	186	Q9UI43
QQGCRSLAWGEPAGS	VWA5B2	706	Q8N398
SLQPRGLINKGNWCY	USP10	411	Q14694
WGQGSSLQKNYPPVC	ZKSCAN7	36	Q9P0L1
GNIWRFPYLCQKNGG	SLC6A17	81	Q9H1V8
GDSGGPLACNKNGLW	PRSS21	236	Q9Y6M0
PLACNKNGLWYQIGV	PRSS21	241	Q9Y6M0
WGDGCAQKNKPGVYT	PRSS1	216	P07477
GAGDGANWLTFFCQP	TRAPPC10	261	P48553
DNGPCTGKVEWFAGS	THSD4	846	Q6ZMP0
IVQGFQWGTREGPLC	EFTUD2	766	Q15029
DCQGGPNALWSAGAT	RS1	41	O15537
QKTTCGQGLEGPWER	PPP1R1B	151	Q9UD71
IFGNADPAQKGGWTR	TCTN3	461	Q6NUS6
NCSAGPKGDNIYEWR	UBE2E1	66	P51965
YGCDNPWTGGIFLIA	SLC14A2	756	Q15849
GVNLIWSCPQGGYEA	PTPRH	681	Q9HD43
VIFINSAGCPGGEGW	USP40	686	Q9NVE5
AFSWRNPDIGYCQGL	TBC1D2B	741	Q9UPU7
SGLPGCYLQVWQVAE	WDR73	101	Q6P4I2
IDWQTGPGCNTAGFF	TSHR	486	P16473
KEDGGGCYDIPNWSA	AGL	916	P35573
GILSWGVYPCGSAQH	KLK10	241	O43240
LAPGLCQEGQIWNGK	MUC12	5126	Q9UKN1
IWNGKQCVCPQGYVG	MUC12	5136	Q9UKN1
PWNAFPGKVCGSNLL	PLP1	211	P60201