Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	GTF2F1 TAF1 TAF2 TAF1L	1.67e-04	52	106	4	GO:0016251
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.76e-04	5	106	2	GO:0061628
GeneOntologyMolecularFunction	general transcription initiation factor binding	BDP1 GTF2F1 TAF1 TAF1L	3.73e-04	64	106	4	GO:0140296
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	GTF2F1 TAF1 TAF1L	3.88e-04	27	106	3	GO:0001091
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	ERCC5 GTF2F1 TAF1 TAF1L	4.20e-04	66	106	4	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	ERCC5 GTF2F1 TAF1 TAF1L	4.20e-04	66	106	4	GO:0001098
GeneOntologyMolecularFunction	general transcription initiation factor activity	GTF2F1 TAF1 TAF2 TAF1L	4.71e-04	68	106	4	GO:0140223
GeneOntologyMolecularFunction	calcium channel activity	CACNA2D1 CACNB3 TRPM2 ITPR2 RIMBP2	6.26e-04	129	106	5	GO:0005262
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2D	7.66e-04	8	106	2	GO:0140945
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	PCLO RIMBP2	7.66e-04	8	106	2	GO:0098882
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	9.81e-04	9	106	2	GO:0001181
GeneOntologyMolecularFunction	LIM domain binding	TLN1 KAT14	9.81e-04	9	106	2	GO:0030274
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2D	1.22e-03	10	106	2	GO:0140999
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA2D1 CACNB3 TRPM2 ITPR2 RIMBP2	1.27e-03	151	106	5	GO:0015085
GeneOntologyMolecularFunction	histone modifying activity	HDAC11 KMT2C KMT2D TAF1 TAF1L KAT14	1.40e-03	229	106	6	GO:0140993
GeneOntologyMolecularFunction	structural constituent of synapse	PPFIA2 PCLO RIMBP2	1.44e-03	42	106	3	GO:0098918
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA2D1 CACNB3 RIMBP2	1.87e-03	46	106	3	GO:0005245
GeneOntologyMolecularFunction	N-acyltransferase activity	TAF1 TAF1L KAT14 CERS4	2.14e-03	102	106	4	GO:0016410
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA2D1 CACNB3 TRPM2 ITPR2 KCNT2 SCN4A RIMBP2	2.37e-03	343	106	7	GO:0005261
GeneOntologyMolecularFunction	histone acetyltransferase activity	TAF1 TAF1L KAT14	2.52e-03	51	106	3	GO:0004402
GeneOntologyMolecularFunction	histone binding	CHD2 SFMBT2 NCAPD2 CHD6 TAF1 TAF1L	2.91e-03	265	106	6	GO:0042393
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	TAF1 TAF1L KAT14	3.12e-03	55	106	3	GO:0061733
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	EAPP ARID4A ZNF423 GON4L ATP8B1 BRMS1L RFX3 TFAP4 ZEB2 SFMBT2 TGIF1 ZBED6 SUPT5H ATF7IP HEY2 TAF1 ST18 KAT14 PBXIP1 NOTCH3 FOXD1 BRMS1	2.85e-06	1399	108	22	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	EAPP ARID4A ZNF423 GON4L ATP8B1 BRMS1L RFX3 TFAP4 ZEB2 SFMBT2 TGIF1 ZBED6 SUPT5H ATF7IP HEY2 TAF1 ST18 KAT14 PBXIP1 NOTCH3 FOXD1 BRMS1	3.35e-06	1413	108	22	GO:1902679
GeneOntologyBiologicalProcess	protein-DNA complex organization	BDP1 HDAC11 ARID4A CHD2 EMSY KMT2C KMT2D SUPT5H ATF7IP HEY2 PWWP3A CHD6 TAF1 TAF2 TAF1L KAT14	6.26e-05	999	108	16	GO:0071824
GeneOntologyCellularComponent	chromatin	ARID4A HLX GON4L CHD2 BRMS1L RFX3 TFAP4 ZEB2 TGIF1 ZBED6 KLF9 PPP4R2 HEY2 CHD6 TAF1 TAF2 MGA TAF1L ST18 KAT14 PBXIP1 FOXD1 BRMS1	1.58e-06	1480	108	23	GO:0000785
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2C KMT2D TAF1 MGA TAF1L	4.34e-05	75	108	5	GO:0035097
GeneOntologyCellularComponent	transcription regulator complex	BDP1 ARID4A RFX3 TFAP4 GTF2F1 ATF7IP HEY2 TAF1 TAF2 MGA TAF1L PBXIP1	5.96e-05	596	108	12	GO:0005667
GeneOntologyCellularComponent	transcription factor TFIID complex	GTF2F1 TAF1 TAF2 TAF1L	1.01e-04	47	108	4	GO:0005669
GeneOntologyCellularComponent	Sin3-type complex	ARID4A BRMS1L BRMS1	1.92e-04	22	108	3	GO:0070822
GeneOntologyCellularComponent	methyltransferase complex	KMT2C KMT2D TAF1 MGA TAF1L	2.45e-04	108	108	5	GO:0034708
GeneOntologyCellularComponent	pronucleus	NCAPD2 TAF1 TAF1L	4.00e-04	28	108	3	GO:0045120
GeneOntologyCellularComponent	MLL1 complex	TAF1 MGA TAF1L	5.96e-04	32	108	3	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	TAF1 MGA TAF1L	6.54e-04	33	108	3	GO:0044665
GeneOntologyCellularComponent	histone deacetylase complex	HDAC11 ARID4A BRMS1L BRMS1	9.89e-04	85	108	4	GO:0000118
GeneOntologyCellularComponent	RNA polymerase II, holoenzyme	GTF2F1 TAF1 TAF2 TAF1L	1.17e-03	89	108	4	GO:0016591
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA2D1 CACNB3	1.69e-03	12	108	2	GO:1990454
GeneOntologyCellularComponent	MLL3/4 complex	KMT2C KMT2D	1.69e-03	12	108	2	GO:0044666
GeneOntologyCellularComponent	nuclear protein-containing complex	HDAC11 ERCC5 ARID4A GON4L BRMS1L KMT2C GTF2F1 KMT2D SUPT5H AFF1 WDR12 TAF1 TAF2 MGA TAF1L BRMS1	1.86e-03	1377	108	16	GO:0140513
GeneOntologyCellularComponent	nuclear chromosome	ERCC5 ARID4A GON4L BRMS1L NCAPD2 BRMS1	2.07e-03	254	108	6	GO:0000228
HumanPheno	Expressive language delay	ZEB2 TGIF1 KMT2C SLC25A36 KMT2D SCN4A TAF1	3.59e-08	56	32	7	HP:0002474
HumanPheno	Language delay	ZEB2 TGIF1 KMT2C SLC25A36 KMT2D SCN4A TAF1	3.59e-08	56	32	7	HP:0002336
HumanPheno	Aplasia/Hypoplasia of the corpus callosum	CACNA2D1 ERCC5 RPGRIP1L ZNF423 PCLO ZEB2 TGIF1 KMT2C KMT2D KCNT2 TECPR2 AP3B2 TAF1 TAF2 TBC1D23	2.01e-05	772	32	15	HP:0007370
HumanPheno	Depressed nasal tip	ZEB2 TGIF1 KMT2D TAF1	2.36e-05	28	32	4	HP:0000437
HumanPheno	Bicuspid aortic valve	ZEB2 KMT2D HEY2 TAF2 ZMYM3 NOTCH3	7.90e-05	119	32	6	HP:0001647
HumanPheno	Thin corpus callosum	CACNA2D1 ERCC5 RPGRIP1L ZNF423 PCLO ZEB2 TGIF1 KMT2C KMT2D KCNT2 TECPR2 AP3B2 TAF1 TAF2 TBC1D23	8.37e-05	868	32	15	HP:0033725
HumanPheno	Abnormal aortic valve cusp morphology	ZEB2 KMT2D HEY2 TAF2 ZMYM3 NOTCH3	8.67e-05	121	32	6	HP:0031567
HumanPheno	Hypoplasia of the corpus callosum	CACNA2D1 PCLO ZEB2 KMT2C KMT2D KCNT2 TECPR2 AP3B2 TAF1 TAF2 TBC1D23	9.18e-05	478	32	11	HP:0002079
HumanPheno	Abnormal cerebral white matter morphology	CACNA2D1 ERCC5 RPGRIP1L ZNF423 PCLO ZEB2 TGIF1 KMT2C KMT2D KCNT2 TECPR2 AP3B2 EIF2B5 TAF1 TAF2 TBC1D23 NOTCH3	1.02e-04	1114	32	17	HP:0002500
HumanPheno	Generalized muscle hypertrophy	ZEB2 SCN4A	1.14e-04	3	32	2	HP:0003720
HumanPheno	Abnormal corpus callosum morphology	CACNA2D1 ERCC5 RPGRIP1L ZNF423 PCLO ZEB2 TGIF1 KMT2C KMT2D KCNT2 TECPR2 AP3B2 TAF1 TAF2 TBC1D23	2.06e-04	937	32	15	HP:0001273
Domain	TAF_II_230-bd	TAF1 TAF1L	3.19e-05	2	106	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	3.19e-05	2	106	2	IPR022591
Domain	-	TAF1 TAF1L	3.19e-05	2	106	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	3.19e-05	2	106	2	PF09247
Domain	DUF3591	TAF1 TAF1L	3.19e-05	2	106	2	PF12157
Domain	TAF1_animal	TAF1 TAF1L	3.19e-05	2	106	2	IPR011177
Domain	Sds3	BRMS1L BRMS1	9.54e-05	3	106	2	PF08598
Domain	Sds3	BRMS1L BRMS1	9.54e-05	3	106	2	SM01401
Domain	Sds3	BRMS1L BRMS1	9.54e-05	3	106	2	IPR013907
Domain	SAM_2	PPFIA2 PPP1R9A SFMBT2 SASH3	1.02e-04	43	106	4	PF07647
Domain	FYrich_C	KMT2C KMT2D	3.16e-04	5	106	2	IPR003889
Domain	FYrich_N	KMT2C KMT2D	3.16e-04	5	106	2	IPR003888
Domain	FYRC	KMT2C KMT2D	3.16e-04	5	106	2	SM00542
Domain	FYRN	KMT2C KMT2D	3.16e-04	5	106	2	SM00541
Domain	FYRN	KMT2C KMT2D	3.16e-04	5	106	2	PF05964
Domain	FYRC	KMT2C KMT2D	3.16e-04	5	106	2	PF05965
Domain	FYRC	KMT2C KMT2D	3.16e-04	5	106	2	PS51543
Domain	FYRN	KMT2C KMT2D	3.16e-04	5	106	2	PS51542
Domain	Di19_Zn_binding_dom	KCMF1 ZEB2	6.58e-04	7	106	2	IPR008598
Domain	zf-Di19	KCMF1 ZEB2	6.58e-04	7	106	2	PF05605
Domain	Chromodomain-like	ARID4A CHD2 CHD6	7.82e-04	32	106	3	IPR016197
Domain	FERM_N	FRMPD1 PTPN14 TLN1	8.57e-04	33	106	3	PF09379
Domain	Chromo/shadow_dom	ARID4A CHD2 CHD6	8.57e-04	33	106	3	IPR000953
Domain	FERM_N	FRMPD1 PTPN14 TLN1	8.57e-04	33	106	3	IPR018979
Domain	CHROMO	ARID4A CHD2 CHD6	8.57e-04	33	106	3	SM00298
Domain	SAM	PPFIA2 PPP1R9A SFMBT2 SASH3	1.59e-03	88	106	4	SM00454
Domain	SAM_DOMAIN	PPFIA2 PPP1R9A SFMBT2 SASH3	2.10e-03	95	106	4	PS50105
Domain	FERM_M	FRMPD1 PTPN14 TLN1	2.26e-03	46	106	3	PF00373
Domain	SAM	PPFIA2 PPP1R9A SFMBT2 SASH3	2.27e-03	97	106	4	IPR001660
Domain	-	FRMPD1 PTPN14 TLN1	2.71e-03	49	106	3	1.20.80.10
Domain	FERM_central	FRMPD1 PTPN14 TLN1	2.71e-03	49	106	3	IPR019748
Domain	FERM_domain	FRMPD1 PTPN14 TLN1	2.71e-03	49	106	3	IPR000299
Domain	FERM_1	FRMPD1 PTPN14 TLN1	2.87e-03	50	106	3	PS00660
Domain	FERM_2	FRMPD1 PTPN14 TLN1	2.87e-03	50	106	3	PS00661
Domain	SANT	BDP1 GON4L CHD6	2.87e-03	50	106	3	SM00717
Domain	FERM_3	FRMPD1 PTPN14 TLN1	2.87e-03	50	106	3	PS50057
Domain	Band_41_domain	FRMPD1 PTPN14 TLN1	2.87e-03	50	106	3	IPR019749
Domain	B41	FRMPD1 PTPN14 TLN1	2.87e-03	50	106	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	FRMPD1 PTPN14 TLN1	2.87e-03	50	106	3	IPR014352
Domain	-	PPFIA2 PPP1R9A SFMBT2 SASH3	3.13e-03	106	106	4	1.10.150.50
Domain	Clathrin/coatomer_adapt-like_N	AP3B2 NCAPD2	3.19e-03	15	106	2	IPR002553
Domain	Adaptin_N	AP3B2 NCAPD2	3.19e-03	15	106	2	PF01602
Domain	ARM-type_fold	GPRASP1 ITPR2 ARFGEF3 AP3B2 EIF2B5 NCAPD2 TAF2	3.21e-03	339	106	7	IPR016024
Domain	SANT/Myb	BDP1 GON4L CHD6	3.21e-03	52	106	3	IPR001005
Domain	Post-SET_dom	KMT2C KMT2D	3.64e-03	16	106	2	IPR003616
Domain	PostSET	KMT2C KMT2D	3.64e-03	16	106	2	SM00508
Domain	POST_SET	KMT2C KMT2D	3.64e-03	16	106	2	PS50868
Domain	SAM/pointed	PPFIA2 PPP1R9A SFMBT2 SASH3	4.45e-03	117	106	4	IPR013761
Domain	TF_GTP-bd_dom	BMS1 EIF5B	5.12e-03	19	106	2	IPR000795
Pathway	REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME	GTF2F1 SUPT5H TAF1 TAF2 TAF1L	2.82e-05	70	72	5	M27008
Pathway	KEGG_BASAL_TRANSCRIPTION_FACTORS	GTF2F1 TAF1 TAF2 TAF1L	2.91e-05	35	72	4	M4864
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	GTF2F1 SUPT5H TAF1 TAF2 TAF1L	5.72e-05	81	72	5	M865
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	GTF2F1 SUPT5H TAF1 TAF2 TAF1L	6.43e-05	83	72	5	MM15314
Pathway	REACTOME_HIV_TRANSCRIPTION_INITIATION	GTF2F1 TAF1 TAF2 TAF1L	9.45e-05	47	72	4	M29568
Pathway	REACTOME_RNA_POLYMERASE_II_PROMOTER_ESCAPE	GTF2F1 TAF1 TAF2 TAF1L	1.03e-04	48	72	4	MM15424
Pubmed	Human transcription factor protein interaction networks.	ARID4A KCMF1 BMS1 GON4L PSMD4 BRMS1L TFAP4 ZEB2 EMSY KMT2C SLC25A36 KMT2D KLF9 ATF7IP CHD6 TAF1 TAF2 MGA TAF1L KAT14 ZMYM3 BRMS1	5.38e-10	1429	109	22	35140242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIAA0513 ZNF423 PPP1R9A FRMPD1 GON4L ZEB2 ARFGEF3 TLN1 RIMBP2 MICAL3 CHD6 ST18 ZMYM3	5.41e-10	407	109	13	12693553
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	BDP1 CACNB3 MIA3 TTLL3 PPFIA2 PPP1R9A TRPM2 FRMPD1 CHD2 ATP8B1 TFAP4 SFMBT2 CEP170 ARFGEF3 KMT2C SLC25A36 TECPR2 AFF1 MICAL3 CHD6 NOTCH3 BRMS1	1.15e-09	1489	109	22	28611215
Pubmed	Interaction network of human early embryonic transcription factors.	ARID4A ZNF423 BRMS1L TFAP4 ZEB2 EMSY KMT2C KMT2D TAF1 MGA KAT14 ZMYM3	1.21e-09	351	109	12	38297188
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	KIAA0513 ARID4A FRMPD1 BMS1 BRMS1L RFX3 TFAP4 ZEB2 EMSY KMT2D NCAPD2 EIF5B MGA ZMYM3 NOTCH3 FOXD1 BRMS1	1.53e-09	857	109	17	25609649
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RPGRIP1L CHD2 BRMS1L ZEB2 DNAAF8 KMT2C KMT2D SUPT5H NCAPD2 CHD6 TAF2 CDCA7L BRMS1	2.99e-09	469	109	13	27634302
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TMA16 PPP1R9A BMS1 GON4L CHD2 EMSY KMT2C GTF2F1 IGFBP5 ZBED6 TLN1 NCAPD2 EIF5B WDR12 CHD6 TAF2 TAF1L PBXIP1 EDRF1 ZMYM3 NOL8	7.24e-09	1497	109	21	31527615
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BDP1 ZSWIM8 GAK RPGRIP1L EMSY ARFGEF3 GTF2F1 PTPN14 SUPT5H ATF7IP PPP4R2 KAT14 ZMYM3	4.30e-08	588	109	13	38580884
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	C14orf93 TMA16 ARID4A CHD2 BRMS1L TFAP4 EMSY KMT2C KMT2D SUPT5H CHD6 MGA TAF1L KAT14 CDCA7L ZMYM3 NOL8 BRMS1	1.12e-07	1294	109	18	30804502
Pubmed	Lost in transcription: molecular mechanisms that control HIV latency.	SUPT5H AFF1 TAF1 TAF2	3.41e-07	19	109	4	23518577
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	PCLO GON4L PSMD4 ZEB2 KMT2C KMT2D SUPT5H ATF7IP TAF1 MGA	5.36e-07	398	109	10	35016035
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	BRMS1L ZEB2 SFMBT2 KMT2D ATF7IP CHD6 TAF1 MGA KAT14 ZMYM3	8.36e-07	418	109	10	34709266
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	GAK EMSY CEP170 KMT2C KMT2D PTPN14 TLN1 NCAPD2 TAF1 TAF2 MGA	1.31e-06	549	109	11	38280479
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	GAK MIA3 PPP1R9A PSMD4 EMSY CEP170 TLN1 MICAL3 PBXIP1	2.12e-06	360	109	9	33111431
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	GAK TMA16 KCMF1 CEP170 EIF5B TAF1 TAF2 TAF1L	2.23e-06	269	109	8	29511261
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	EMSY CHD6 TAF1 TAF2 MGA KAT14	2.73e-06	124	109	6	20850016
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	BMS1 PSMD4 EMSY SUPT5H TAF1 MGA TAF1L NOL8	3.25e-06	283	109	8	30585729
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TMA16 ARID4A CHD2 ZEB2 EMSY WDR12 CHD6 TAF1 TAF2 MGA ZMYM3	3.48e-06	608	109	11	36089195
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	GON4L CHD2 BRMS1L CEP170 IGFBP5 TLN1 HEY2 TAF1 MGA NOTCH3	3.91e-06	497	109	10	23414517
Pubmed	Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.	KMT2C KMT2D	9.73e-06	2	109	2	28483418
Pubmed	TAFII250 is a bipartite protein kinase that phosphorylates the base transcription factor RAP74.	GTF2F1 TAF1	9.73e-06	2	109	2	8625415
Pubmed	The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.	KMT2C KMT2D	9.73e-06	2	109	2	34156443
Pubmed	Kinase activity and phosphorylation of the largest subunit of TFIIF transcription factor.	GTF2F1 TAF1	9.73e-06	2	109	2	10428810
Pubmed	KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.	KMT2C KMT2D	9.73e-06	2	109	2	31924266
Pubmed	Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.	KMT2C KMT2D	9.73e-06	2	109	2	27280393
Pubmed	Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells.	ARID4A BRMS1	9.73e-06	2	109	2	18211900
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	9.73e-06	2	109	2	38804708
Pubmed	Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.	KMT2C KMT2D	9.73e-06	2	109	2	36869380
Pubmed	DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex recognizes the initiator.	TAF1 TAF2	9.73e-06	2	109	2	10469661
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	9.73e-06	2	109	2	10070062
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	9.73e-06	2	109	2	22842574
Pubmed	Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.	KMT2C KMT2D	9.73e-06	2	109	2	28967912
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	9.73e-06	2	109	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	9.73e-06	2	109	2	34403156
Pubmed	A 7q21.11 microdeletion presenting with apparent intellectual disability without epilepsy.	CACNA2D1 PCLO	9.73e-06	2	109	2	28240412
Pubmed	Functional characterization of CaVα2δ mutations associated with sudden cardiac death.	CACNA2D1 CACNB3	9.73e-06	2	109	2	25527503
Pubmed	Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.	KMT2C KMT2D	9.73e-06	2	109	2	25346535
Pubmed	Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.	KMT2C KMT2D	9.73e-06	2	109	2	36601880
Pubmed	Mapping the Genetic Landscape of Human Cells.	BDP1 PSMD4 EMSY EIF2B5 NCAPD2 EIF5B TAF1 TAF2 NOL8	1.30e-05	451	109	9	30033366
Pubmed	The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.	TAF1 TAF2 TAF1L	1.33e-05	15	109	3	14580349
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KIAA0513 PCLO ZEB2 MGA ST18	2.07e-05	105	109	5	9628581
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	BDP1 ERCC5 KMT2D PPP4R2 AFF1	2.17e-05	106	109	5	31024071
Pubmed	The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.	HEY2 TAF1 TAF2 TAF1L	2.20e-05	52	109	4	28893950
Pubmed	Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.	GTF2F1 TAF1 TAF2	2.36e-05	18	109	3	15053879
Pubmed	Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.	TFAP4 TAF1 TAF2	2.36e-05	18	109	3	7933101
Pubmed	Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.	ARID4A BRMS1L BRMS1	2.80e-05	19	109	3	22984288
Pubmed	Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.	ARID4A BRMS1L BRMS1	2.80e-05	19	109	3	28554894
Pubmed	Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone.	ARID4A TAF1 BRMS1	2.80e-05	19	109	3	16919237
Pubmed	A census of human transcription factors: function, expression and evolution.	HLX ZNF200 GON4L RFX3 TFAP4 ZEB2 TGIF1 KMT2D KLF9 HEY2 MGA ST18	2.88e-05	908	109	12	19274049
Pubmed	A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.	ZEB2 NOTCH3	2.91e-05	3	109	2	21890822
Pubmed	Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.	CACNA2D1 CACNB3	2.91e-05	3	109	2	11160515
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	2.91e-05	3	109	2	16822332
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2C KMT2D	2.91e-05	3	109	2	23932714
Pubmed	Downregulation of transforming growth factor, beta receptor 2 and Notch signaling pathway in human abdominal aortic aneurysm.	HEY2 NOTCH3	2.91e-05	3	109	2	22310065
Pubmed	IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.	SCHIP1 IQCJ-SCHIP1	2.91e-05	3	109	2	17045569
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2C KMT2D	2.91e-05	3	109	2	22183980
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	2.91e-05	3	109	2	11592977
Pubmed	EMC chaperone-CaV structure reveals an ion channel assembly intermediate.	CACNA2D1 CACNB3	2.91e-05	3	109	2	37196677
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	2.91e-05	3	109	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	2.91e-05	3	109	2	16407123
Pubmed	Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation.	GTF2F1 TAF1	2.91e-05	3	109	2	7590250
Pubmed	HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.	KMT2C KMT2D	2.91e-05	3	109	2	21683083
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	KCMF1 ZEB2 SUPT5H NCAPD2 AKAP11 CHD6 TAF2	3.15e-05	282	109	7	23667531
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2C KMT2D TAF1 TAF1L	3.17e-05	57	109	4	18022353
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ERCC5 ARID4A TFAP4 EMSY OSBP KMT2D EIF2B5 EIF5B AFF1 MICAL3 ZMYM3	3.28e-05	774	109	11	15302935
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 BMS1 CHD2 CEP170 SUPT5H TLN1 NCAPD2 EIF5B WDR12 ZMYM3	4.09e-05	653	109	10	22586326
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TMA16 TFAP4 ZEB2 EMSY CEP170 TGIF1 KMT2C GTF2F1 KMT2D PPP4R2 TLN1 EIF5B ZMYM3	4.29e-05	1103	109	13	34189442
Pubmed	SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex.	ARID4A BRMS1L BRMS1	5.07e-05	23	109	3	9651585
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2C KMT2D	5.82e-05	4	109	2	19221051
Pubmed	Cancer gene mutation frequencies for the U.S. population.	KMT2C KMT2D	5.82e-05	4	109	2	34645806
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2C KMT2D	5.82e-05	4	109	2	28398509
Pubmed	Functional analysis of the human TAFII250 N-terminal kinase domain.	GTF2F1 TAF1	5.82e-05	4	109	2	9660973
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2C KMT2D	5.82e-05	4	109	2	23129768
Pubmed	Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.	SCHIP1 IQCJ-SCHIP1	5.82e-05	4	109	2	27979964
Pubmed	The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.	KMT2C KMT2D	5.82e-05	4	109	2	24081332
Pubmed	Rb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250.	GTF2F1 TAF1	5.82e-05	4	109	2	9858607
Pubmed	TAF1 histone acetyltransferase activity in Sp1 activation of the cyclin D1 promoter.	TAF1 TAF2	5.82e-05	4	109	2	15870300
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	EMSY GTF2F1 SUPT5H MGA KAT14 NOL8	7.41e-05	222	109	6	37071664
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	SCHIP1 IQCJ-SCHIP1	9.67e-05	5	109	2	25950943
Pubmed	Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.	KMT2C KMT2D	9.67e-05	5	109	2	31127101
Pubmed	Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.	SCHIP1 IQCJ-SCHIP1	9.67e-05	5	109	2	18550753
Pubmed	Identification of KIAA0513 and Other Hub Genes Associated With Alzheimer Disease Using Weighted Gene Coexpression Network Analysis.	KIAA0513 AP3B2	9.67e-05	5	109	2	33005179
Pubmed	A dynamic model for PC4 coactivator function in RNA polymerase II transcription.	GTF2F1 TAF1	9.67e-05	5	109	2	9482861
Pubmed	MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ.	KMT2C KMT2D	9.67e-05	5	109	2	32601106
Pubmed	A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.	KMT2C KMT2D	9.67e-05	5	109	2	26744420
Pubmed	Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.	GTF2F1 TAF1 TAF2 TAF1L	9.84e-05	76	109	4	22323595
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MIA3 RPGRIP1L PPP1R9A BMS1 PSMD4 ITPR2 GTF2F1 KMT2D PTPN14 SUPT5H PPP4R2 MICAL3	1.14e-04	1049	109	12	27880917
Pubmed	Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.	PPFIA2 TAF1 TAF1L	1.26e-04	31	109	3	25838543
Pubmed	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.	KMT2D TAF1 MGA	1.26e-04	31	109	3	15960975
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MYH6 GAK ERCC5 CHD2 ITPR2 CEP170 TLN1 EIF5B AFF1 AKAP11 TAF1L	1.38e-04	910	109	11	36736316
Pubmed	Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation.	TAF1 TAF2	1.45e-04	6	109	2	7680771
Pubmed	Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.	TAF1 TAF1L	1.45e-04	6	109	2	19959467
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	KMT2C KMT2D	1.45e-04	6	109	2	17021013
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HDAC11 CACNA2D1 MYH6 GAK PPFIA2 PCLO PPP1R9A ITPR2 CEP170 TLN1 AP3B2 RIMBP2 MICAL3 PBXIP1	1.56e-04	1431	109	14	37142655
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	BMS1 OSBP SUPT5H NCAPD2 EIF5B	1.68e-04	163	109	5	22113938
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	PSMD4 BRMS1L KMT2C KMT2D MGA KAT14 ZMYM3 BRMS1	1.72e-04	495	109	8	27705803
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	C14orf93 RETREG2 PCLO KCMF1 PSMD4 CEP170 PTPN14 PBXIP1	1.82e-04	499	109	8	22810586
Pubmed	Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.	GTF2F1 EIF2B5 EIF5B	1.98e-04	36	109	3	16097034
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ARID4A KCMF1 GON4L CEP170 GTF2F1 TLN1 MICAL3 CHD6 EDRF1	2.02e-04	645	109	9	25281560
Pubmed	Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4.	KMT2C KMT2D	2.02e-04	7	109	2	30604749
Interaction	KLF3 interactions	ARID4A ZNF423 BRMS1L ZEB2 EMSY KMT2D ATF7IP CHD6 TAF1 MGA KAT14 ZMYM3	3.93e-09	228	109	12	int:KLF3
Interaction	KLF9 interactions	ARID4A BMS1 GON4L BRMS1L EMSY KLF9 MGA BRMS1	3.93e-08	93	109	8	int:KLF9
Interaction	FEV interactions	BRMS1L ZEB2 EMSY KMT2C KMT2D CHD6 TAF1 TAF2 MGA ZMYM3	1.54e-07	203	109	10	int:FEV
Interaction	KLF16 interactions	KCMF1 GON4L PSMD4 BRMS1L TFAP4 ZEB2 EMSY KMT2D TAF1 MGA ZMYM3 BRMS1	3.28e-06	425	109	12	int:KLF16
Interaction	CSNK2A1 interactions	BDP1 ERCC5 BMS1 HLX BRMS1L ZEB2 CEP170 OSBP GTF2F1 CCDC82 SUPT5H EIF2B5 NCAPD2 EIF5B WDR12 TAF1 MGA BRMS1	3.55e-06	956	109	18	int:CSNK2A1
Interaction	ELK3 interactions	BRMS1L ZEB2 EMSY CHD6 TAF1 TAF2 MGA	4.01e-06	120	109	7	int:ELK3
Interaction	HDAC1 interactions	ARID4A ZNF423 GON4L BRMS1L RFX3 TFAP4 ZEB2 EMSY TGIF1 KMT2D TLN1 NCAPD2 HEY2 AFF1 TAF1 MGA KAT14 ZMYM3 BRMS1	7.10e-06	1108	109	19	int:HDAC1
Interaction	KLF12 interactions	BRMS1L ZEB2 EMSY ATF7IP CHD6 MGA KAT14 ZMYM3	1.06e-05	194	109	8	int:KLF12
Interaction	SIN3B interactions	ARID4A BRMS1L TFAP4 EMSY KLF9 SCN4A BRMS1	1.52e-05	147	109	7	int:SIN3B
Interaction	HNF4A interactions	BRMS1L ZEB2 EMSY KMT2C KMT2D ATF7IP MGA KAT14 ZMYM3	1.87e-05	275	109	9	int:HNF4A
Interaction	FOXK2 interactions	KIAA0513 ARID4A BRMS1L TFAP4 EMSY KMT2D EIF5B BRMS1	3.08e-05	225	109	8	int:FOXK2
Interaction	NFIX interactions	BRMS1L TFAP4 ZEB2 EMSY KMT2C KMT2D MGA KAT14	3.28e-05	227	109	8	int:NFIX
Interaction	NUP43 interactions	ERCC5 ARID4A BMS1 GON4L CLSTN2 EMSY KMT2D ATF7IP EIF2B5 CHD6 TAF2 MGA ZMYM3	3.31e-05	625	109	13	int:NUP43
Interaction	SIN3A interactions	ARID4A GON4L BRMS1L TFAP4 TGIF1 KLF9 HEY2 TAF1 ZMYM3 BRMS1	4.10e-05	380	109	10	int:SIN3A
Interaction	CRAMP1 interactions	GON4L PPP4R2 AKAP11 PIPSL	4.66e-05	37	109	4	int:CRAMP1
Interaction	ELF1 interactions	BRMS1L EMSY TAF1 TAF2 MGA BRMS1	6.34e-05	126	109	6	int:ELF1
Interaction	LHX3 interactions	BRMS1L ZEB2 KMT2C KMT2D TAF1 MGA TAF1L	6.64e-05	185	109	7	int:LHX3
Interaction	POLR1G interactions	BMS1 CHD2 ZEB2 GTF2F1 SUPT5H ATF7IP TAF1 TAF2 MGA ZMYM3 NOL8	6.92e-05	489	109	11	int:POLR1G
Interaction	KLF8 interactions	PSMD4 BRMS1L ZEB2 EMSY KMT2D ATF7IP TAF2 MGA ZMYM3	7.52e-05	329	109	9	int:KLF8
Interaction	HNF1B interactions	BRMS1L ZEB2 KMT2C KMT2D ATF7IP MGA BRMS1	7.85e-05	190	109	7	int:HNF1B
Interaction	MXD1 interactions	ARID4A BRMS1L MGA BRMS1	1.02e-04	45	109	4	int:MXD1
Interaction	PAX6 interactions	BRMS1L TFAP4 ZEB2 KMT2C KMT2D CHD6 TAF1 MGA ZMYM3	1.68e-04	366	109	9	int:PAX6
Interaction	BRMS1 interactions	ARID4A BRMS1L KLF9 TAF1 BRMS1	1.74e-04	96	109	5	int:BRMS1
Interaction	YY1 interactions	GON4L BRMS1L EMSY KLF9 ATF7IP TAF1 TAF2 MGA KAT14 ZMYM3	1.78e-04	454	109	10	int:YY1
Interaction	PHF20 interactions	KMT2C PTPN14 TAF1 KAT14	1.93e-04	53	109	4	int:PHF20
Interaction	ELF2 interactions	ARID4A BRMS1L EMSY TAF2 MGA BRMS1	2.05e-04	156	109	6	int:ELF2
Interaction	ARRDC2 interactions	ZSWIM8 KCMF1 PSMD4 PIPSL	2.08e-04	54	109	4	int:ARRDC2
GeneFamily	Sterile alpha motif domain containing	PPFIA2 PPP1R9A SFMBT2 SASH3	4.65e-04	88	74	4	760
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RPGRIP1L PPP1R9A ARFGEF3 AKAP11 RIMBP2	8.77e-04	181	74	5	694
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMPD1 PTPN14 TLN1	1.12e-03	50	74	3	1293
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	BDP1 GON4L CHD6	1.33e-03	53	74	3	532
Coexpression	GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN	ARID4A CHD2 RFX3 SFMBT2 ITPR2 CCDC82 NCAPD2 AFF1 TAF1	1.49e-07	200	108	9	M6745
Coexpression	GAO_LARGE_INTESTINE_ADULT_CA_ENTEROENDOCRINE_CELLS	GPRASP1 CACNA2D1 PPFIA2 PCLO RFX3 CEP170 AP3B2 C19orf44 RIMBP2 ST18	6.84e-07	312	108	10	M39161
Coexpression	GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP	SIDT1 CHD2 ITPR2 PTPN14 MGA PBXIP1 CERS4	1.85e-05	198	108	7	M6025
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	MIA3 PPP1R9A GON4L CHD2 ATF7IP C19orf44 MGA CDCA7L	8.02e-09	166	109	8	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO TRPM2 CLSTN2 AP3B2 RIMBP2 ST18	2.86e-07	178	109	7	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	CACNA2D1 ARID4A PPFIA2 PCLO ZEB2 CEP170 ARFGEF3	6.06e-07	199	109	7	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO OSBP AFF1 AKAP11 RIMBP2	4.47e-06	174	109	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 PCLO ARFGEF3 AP3B2 RIMBP2 ST18	4.77e-06	176	109	6	2e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPRASP1 MYH6 ZEB2 KCNT2 ZBED6 ATF7IP	4.77e-06	176	109	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO AFF1 AKAP11 RIMBP2 ST18	5.09e-06	178	109	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN2 SFMBT2 TMEM91 KCNT2 TBC1D23 NOTCH3	5.26e-06	179	109	6	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	C14orf93 ARMCX4 TMEM91 OSBP MICAL3 CDCA7L	6.16e-06	184	109	6	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	C14orf93 ARMCX4 TMEM91 OSBP MICAL3 CDCA7L	6.35e-06	185	109	6	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	droplet-Pancreas\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPRASP1 CACNA2D1 PCLO ARFGEF3 AP3B2 ST18	6.75e-06	187	109	6	5f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Neuroendocrine\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC11 PPFIA2 PCLO IGFBP5 AP3B2 ST18	7.62e-06	191	109	6	501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPRASP1 CACNA2D1 PCLO AP3B2 RIMBP2 ST18	7.62e-06	191	109	6	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO ATP8B1 AP3B2 RIMBP2 ST18	7.62e-06	191	109	6	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	facs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC11 PPFIA2 PCLO IGFBP5 AP3B2 ST18	7.62e-06	191	109	6	8e06cc61eaff1796c2ce014074029408ba88d561
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO ATP8B1 AP3B2 RIMBP2 ST18	7.85e-06	192	109	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 PPP1R9A RFX3 ITPR2 SLC25A36 CHD6	8.09e-06	193	109	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	C14orf93 PPP1R9A CLSTN2 ARMCX4 LRGUK TBC1D23	8.09e-06	193	109	6	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 MIA3 PCLO KMT2C MGA ST18	8.58e-06	195	109	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 MIA3 PCLO KMT2C MGA ST18	8.58e-06	195	109	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	BDP1 CACNA2D1 PCLO ZEB2 CEP170 ARFGEF3	9.63e-06	199	109	6	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	BDP1 CACNA2D1 PCLO ZEB2 CEP170 ARFGEF3	9.63e-06	199	109	6	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	Neuron\|World / Primary Cells by Cluster	ARID4A PPFIA2 PCLO ZEB2 CEP170 ARFGEF3	9.63e-06	199	109	6	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	ARID4A PPFIA2 PCLO ZEB2 CEP170 ARFGEF3	9.63e-06	199	109	6	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer\|World / Primary Cells by Cluster	BDP1 CACNA2D1 PCLO ZEB2 CEP170 ARFGEF3	9.91e-06	200	109	6	db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21\|World / Primary Cells by Cluster	BDP1 CACNA2D1 PCLO ZEB2 CEP170 ARFGEF3	9.91e-06	200	109	6	30a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCLO ARFGEF3 AP3B2 RIMBP2 ST18	4.50e-05	159	109	5	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 RFX3 ARFGEF3 RIMBP2 ST18	5.36e-05	165	109	5	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIAA0513 LRRC43 ARFGEF3 RIMBP2 FOXD1	6.18e-05	170	109	5	985c2d5962100fab0d95bee39f382ccbe799331e
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCLO ARFGEF3 AP3B2 RIMBP2 ST18	6.18e-05	170	109	5	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 CLSTN2 ZEB2 GPR153 HEY2	6.18e-05	170	109	5	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCLO ARFGEF3 WDR87 RIMBP2 ST18	6.35e-05	171	109	5	fa5cc720bd0045d0307439be547b41d56def5b43
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	CACNA2D1 IGFBP5 HEY2 MICAL3 NOTCH3	6.53e-05	172	109	5	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TFAP4 SLC25A36 KCNT2 NCAPD2 TAF2	6.53e-05	172	109	5	c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TFAP4 SLC25A36 KCNT2 NCAPD2 TAF2	6.53e-05	172	109	5	bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA2D1 PPFIA2 IGFBP5 MICAL3 NOTCH3	6.71e-05	173	109	5	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 CEP170 PTPN14 GPR153 ST18	7.08e-05	175	109	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL3 CHRM1 SFMBT2 HEY2 NOTCH3	7.47e-05	177	109	5	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCHIP1 TTLL3 ARMCX4 AP3B2 ST18	7.47e-05	177	109	5	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTLL3 CHRM1 SFMBT2 HEY2 NOTCH3	7.47e-05	177	109	5	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 ARFGEF3 AP3B2 RIMBP2 FOXD1	7.88e-05	179	109	5	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO AP3B2 RIMBP2 ST18	8.09e-05	180	109	5	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	droplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 MYH6 CLSTN2 HEY2 NOTCH3	8.09e-05	180	109	5	b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 PCLO ARFGEF3 RIMBP2 ST18	8.09e-05	180	109	5	6b1606238417490e0d9930870a7827419d1c3737
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 PCLO ARFGEF3 RIMBP2 ST18	8.30e-05	181	109	5	af031661af28f99d906d8e013b4949133b44a2e6
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 FRMPD1 CLSTN2 HEY2 NOTCH3	8.52e-05	182	109	5	9edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	CACNA2D1 PCLO AP3B2 RIMBP2 ST18	8.52e-05	182	109	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 FRMPD1 CLSTN2 HEY2 NOTCH3	8.52e-05	182	109	5	aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MYH6 FRMPD1 ARFGEF3 AP3B2 RIMBP2	8.75e-05	183	109	5	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 RFX3 SFMBT2 RIMBP2 ST18	8.75e-05	183	109	5	49f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 PCLO CHRM1 ARFGEF3 ST18	8.97e-05	184	109	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 PCLO AP3B2 RIMBP2 ST18	8.97e-05	184	109	5	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CACNA2D1 PPFIA2 CLSTN2 ZEB2 ITPR2	8.97e-05	184	109	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 PCLO CHRM1 ARFGEF3 ST18	8.97e-05	184	109	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 PCLO CHRM1 ARFGEF3 ST18	8.97e-05	184	109	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 PCLO ARFGEF3 RIMBP2 ST18	9.20e-05	185	109	5	eb78614c4acf8d2ce7874d7e51e16997b76127ef
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO CLSTN2 ARMCX4 AP3B2 RIMBP2	9.20e-05	185	109	5	2a8104f610fa5ce618f8105521616722462a0d42
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCMF1 TGIF1 ZBED6 PPP4R2 AFF1	9.20e-05	185	109	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PPFIA2 PCLO ZEB2 KMT2C TLN1	9.44e-05	186	109	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA2D1 KCNT2 IGFBP5 HEY2 NOTCH3	9.44e-05	186	109	5	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCLO ARFGEF3 IGFBP5 AP3B2 ST18	9.44e-05	186	109	5	dfd67d67c103c942de6c8acef8d81e57a9886154
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C14orf93 PPFIA2 HLX KCNT2 KLF9	9.44e-05	186	109	5	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCLO ARFGEF3 AP3B2 RIMBP2 ST18	9.44e-05	186	109	5	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CHD2 ZEB2 KMT2C ZBED6 ATF7IP	9.93e-05	188	109	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCLO ARFGEF3 AP3B2 RIMBP2 ST18	9.93e-05	188	109	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	PCLO IGFBP5 AP3B2 RIMBP2 ST18	9.93e-05	188	109	5	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	MYH6 PPP1R9A SLC25A36 MICAL3 IQCJ-SCHIP1	1.02e-04	189	109	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	ASK452-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	PPFIA2 BMS1 GPR153 PBXIP1 NOL8	1.02e-04	189	109	5	f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA2D1 PPFIA2 IGFBP5 RIMBP2 ST18	1.04e-04	190	109	5	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA2D1 PPFIA2 IGFBP5 RIMBP2 ST18	1.04e-04	190	109	5	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA2D1 PPFIA2 IGFBP5 RIMBP2 ST18	1.04e-04	190	109	5	a9a705455019e28d655636de73b07540798f82e6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA2 ZEB2 KCNT2 HEY2 NOTCH3	1.04e-04	190	109	5	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PPFIA2 ATP8B1 IGFBP5 HEY2 NOTCH3	1.04e-04	190	109	5	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA2D1 KCNT2 IGFBP5 HEY2 NOTCH3	1.07e-04	191	109	5	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CACNA2D1 ZEB2 KCNT2 HEY2 NOTCH3	1.07e-04	191	109	5	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	CACNA2D1 PPFIA2 IGFBP5 HEY2 NOTCH3	1.07e-04	191	109	5	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 PPP1R9A ITPR2 SLC25A36 CHD6	1.10e-04	192	109	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D1 PCLO ARFGEF3 RIMBP2 ST18	1.10e-04	192	109	5	0b506fb5bca54a50949932293c6f86d974a3acdd
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PCLO PPP1R9A ATP8B1 ARFGEF3 RIMBP2	1.10e-04	192	109	5	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	Neuroendocrine\|World / Class top	CACNA2D1 IGFBP5 AP3B2 RIMBP2 ST18	1.10e-04	192	109	5	0199da3ef9ddb6673e9aa41f346f374838aec182
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCHIP1 IGFBP5 TLN1 HEY2 NOTCH3	1.12e-04	193	109	5	7631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA2D1 MYH6 PPP1R9A MICAL3 IQCJ-SCHIP1	1.12e-04	193	109	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	TRPM2 ZEB2 SFMBT2 ITPR2 CEP170	1.12e-04	193	109	5	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SCHIP1 ZNF423 PPP1R9A ATP8B1 SFMBT2	1.12e-04	193	109	5	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCHIP1 IGFBP5 TLN1 HEY2 NOTCH3	1.12e-04	193	109	5	8d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	GPRASP1 PPFIA2 CLSTN2 ARFGEF3 RIMBP2	1.12e-04	193	109	5	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PCLO PPP1R9A ARFGEF3 RIMBP2 ST18	1.15e-04	194	109	5	b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN2 ZEB2 IGFBP5 HEY2 NOTCH3	1.18e-04	195	109	5	6e875c83f838241b5fcaf4a3249b1408d74521dc
ToppCell	(08)_PNEC\|World / shred by cell type and Timepoint	CACNA2D1 PCLO CLSTN2 AP3B2 ST18	1.21e-04	196	109	5	2ee37155c03cd5009427a4bffe6c80ed2ac6939e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ATP8B1 BRMS1L TFAP4 C19orf44 CERS4	1.21e-04	196	109	5	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PPFIA2 CLSTN2 KCNT2 KLF9 NOTCH3	1.24e-04	197	109	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRPM2 ZEB2 SFMBT2 ITPR2 CEP170	1.24e-04	197	109	5	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	BDP1 ARID4A CHD2 EIF5B NOL8	1.24e-04	197	109	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TRPM2 ZEB2 SFMBT2 ITPR2 CEP170	1.24e-04	197	109	5	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRPM2 ZEB2 SFMBT2 TPRG1 ST18	1.27e-04	198	109	5	6a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CLSTN2 ZEB2 KCNT2 IGFBP5 NOTCH3	1.27e-04	198	109	5	b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZEB2 KMT2C SASH3 ZBED6 TLN1	1.30e-04	199	109	5	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Cortical_neuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	CACNA2D1 PPFIA2 ZEB2 GPR153 NOL8	1.33e-04	200	109	5	7bba2ff09349c8db3d1ccf53520b12cbf7b0abac
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BDP1 CHD2 ZEB2 KMT2C ATF7IP	1.33e-04	200	109	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	PPFIA2 ZEB2 KCNT2 IGFBP5 NOTCH3	1.33e-04	200	109	5	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	HDAC11 MIA3 TFAP4 GPR153 HEY2 EIF5B MGA CERS4	3.96e-06	195	107	8	2653_UP
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	GPRASP1 C14orf93 MIA3 RETREG2 EMSY KLF9 PBXIP1	2.84e-05	186	107	7	1664_UP
Drug	Lithocholic acid [434-13-9]; Up 200; 10.6uM; HL60; HT_HG-U133A	CACNA2D1 PCLO KLF9 GPR153 MICAL3 PBXIP1 EDRF1	2.94e-05	187	107	7	2571_UP
Drug	Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; MCF7; HT_HG-U133A	KIAA0513 PCLO RCBTB2 CLSTN2 IGFBP5 AFF1 PBXIP1	3.15e-05	189	107	7	4688_UP
Drug	Metampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	HDAC11 TMA16 PCLO EMSY PTPN14 PBXIP1 NOTCH3	3.48e-05	192	107	7	2123_UP
Drug	Ethacrynic acid [58-54-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A	MIA3 ZNF423 PCLO PPP1R9A AP3B2 AFF1 PBXIP1	3.84e-05	195	107	7	3181_UP
Drug	Lovastatin [75330-75-5]; Down 200; 9.8uM; HL60; HT_HG-U133A	C14orf93 CACNB3 TMA16 ITPR2 TECPR2 PBXIP1 EDRF1	4.10e-05	197	107	7	2494_DN
Drug	Minocycline hydrochloride [13614-98-7]; Up 200; 8uM; MCF7; HT_HG-U133A	RPGRIP1L TRPM2 RCBTB2 EMSY IGFBP5 TECPR2 EDRF1	4.10e-05	197	107	7	5496_UP
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	CACNB3 GON4L ATP8B1 SLC25A36 KLF9 EDRF1 CERS4	4.23e-05	198	107	7	3294_DN
Drug	raloxifene hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A	ZSWIM8 ATP8B1 TFAP4 IGFBP5 AFF1 PBXIP1 NOTCH3	4.23e-05	198	107	7	202_DN
Drug	Molsidomine [25717-80-0]; Down 200; 16.6uM; MCF7; HT_HG-U133A	C14orf93 TMA16 RCBTB2 TFAP4 PTPN14 TLN1 EIF5B	4.37e-05	199	107	7	2862_DN
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A	MYH6 EMSY KMT2D IGFBP5 AFF1 RIMBP2 TAF1	4.37e-05	199	107	7	6444_UP
Drug	Domperidone maleate; Up 200; 7.4uM; MCF7; HT_HG-U133A	TFAP4 IGFBP5 TECPR2 GPR153 TLN1 PWWP3A CERS4	4.37e-05	199	107	7	2655_UP
Disease	Kleefstra syndrome 2 (implicated_via_orthology)	KMT2C KMT2D	1.25e-05	2	105	2	DOID:0080598 (implicated_via_orthology)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD2 CHD6	2.60e-04	7	105	2	DOID:0050834 (implicated_via_orthology)
Disease	Cerebellar Diseases	RPGRIP1L ZEB2	2.60e-04	7	105	2	C0007760
Disease	corpus callosum volume measurement	CACNA2D1 SCHIP1 TLN1 IQCJ-SCHIP1	4.57e-04	100	105	4	EFO_0010299
Disease	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	ATF7IP MGA	8.09e-04	12	105	2	C0023485
Disease	Brugada Syndrome 1	CACNA2D1 HEY2	9.54e-04	13	105	2	C4551804
Disease	Impaired cognition	EIF2B5 NOTCH3	1.11e-03	14	105	2	C0338656
Disease	trimethylamine-N-oxide measurement	ITPR2 ST18	1.11e-03	14	105	2	EFO_0010541
Disease	Sinus Node Dysfunction (disorder)	CACNA2D1 MYH6	1.28e-03	15	105	2	C0428908
Disease	T-Cell Lymphoma	KMT2D MGA	1.46e-03	16	105	2	C0079772
Disease	Pontoneocerebellar hypoplasia	PCLO TBC1D23	1.46e-03	16	105	2	cv:C1261175
Disease	Malignant neoplasm of breast	FRMPD1 ATP8B1 ZEB2 EMSY KMT2D PTPN14 KCNT2 IGFBP5 HEY2 AFF1 NOTCH3	1.55e-03	1074	105	11	C0006142
Disease	Bladder Neoplasm	KMT2C KMT2D IGFBP5 CHD6	1.60e-03	140	105	4	C0005695
Disease	Prostatic Neoplasms	ARID4A KMT2C KMT2D CHD6 MGA TAF1L ZMYM3 NOL8	1.63e-03	616	105	8	C0033578
Disease	Malignant neoplasm of prostate	ARID4A KMT2C KMT2D CHD6 MGA TAF1L ZMYM3 NOL8	1.63e-03	616	105	8	C0376358
Disease	Malignant neoplasm of urinary bladder	KMT2C KMT2D IGFBP5 CHD6	1.64e-03	141	105	4	C0005684
Disease	congenital heart disease (implicated_via_orthology)	KMT2C KMT2D CHD6	1.93e-03	69	105	3	DOID:1682 (implicated_via_orthology)
Disease	bipolar disorder, body mass index	RPGRIP1L CLSTN2 SLC25A36	2.19e-03	72	105	3	EFO_0004340, MONDO_0004985
Disease	body fat percentage, coronary artery disease	MIA3 WDR12	3.29e-03	24	105	2	EFO_0001645, EFO_0007800
Disease	Carcinoma, Pancreatic Ductal	HEY2 NOTCH3	3.29e-03	24	105	2	C0887833
Disease	Brugada Syndrome (disorder)	CACNA2D1 HEY2	3.29e-03	24	105	2	C1142166

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDLVPMEESEDSQSD	C2orf16	1041	Q68DN1
RERSESLDPDSSMDT	CEP170	876	Q5SW79
DPDESMSSRISDTER	BDP1	416	A6H8Y1
SDRTISDEDESDEDM	AGBL3	11	Q8NEM8
MEKDIRSDVEESDSS	CERS4	336	Q9HA82
MDISEILESSSSDDE	ARID4A	266	P29374
ERDSLMPSDEASESS	CACNB3	396	P54284
SDSMLVEAREASEED	HDAC11	56	Q96DB2
GESESSSEDEFEKEM	EAPP	51	Q56P03
MKDDIEDSDSEVSEF	AKAP11	341	Q9UKA4
EEEAEEEMSSSSGSD	CLSTN2	906	Q9H4D0
EEMSSSSGSDDSEEE	CLSTN2	911	Q9H4D0
EEDSEMDLPAFADSD	BMS1	491	Q14692
DKSMSTSEAEATAED	ARMCX4	1046	Q5H9R4
MSTERDSETTFDEDS	ATP8B1	1	O43520
SESEMTSESEEEQLE	AP3B2	771	Q13367
SSLEDNEDDIVEMSE	RCBTB2	421	O95199
EMSDASGLAEETDID	FOXD1	6	Q16676
DNPMESSILSDDIDD	ITPR2	676	Q14571
LESPDEDMGSDSDVT	KLF9	86	Q13886
ETTESADSENDMGES	KIAA0513	46	O60268
EETTSESDMDETIDV	HEY2	6	Q9UBP5
VASSSSESEMEEEGE	MICAL3	931	Q7RTP6
TAVEDEDSMDGLETT	KMT2C	61	Q8NEZ4
SESLDMAPSDTERTE	HLX	381	Q14774
EPEVEEDMSASDSDD	RPGRIP1L	1071	Q68CZ1
SSELLTNMEDEDDTD	MGA	2806	Q8IWI9
TNMEDEDDTDETLTS	MGA	2811	Q8IWI9
SDESYSEEEEEMPDS	EDRF1	531	Q3B7T1
DPTEMASLDSDEETV	FAM174C	111	Q9BVV8
ADLSDEDEVDTMSPT	KIAA1109	3496	Q2LD37
ESESEQSMDSEEPDS	EIF2B5	526	Q13144
IEMSADEDASGSEDD	PCLO	1561	Q9Y6V0
PDRMDIDSEDTDSNT	KAT14	421	Q9H8E8
ALMANDEESDDETSL	GPR153	316	Q6NV75
MPTEEDEADDTSASI	NOTCH3	1806	Q9UM47
SREHEEPTTSEMAEE	IGFBP5	116	P24593
GSEESSESEMLNLEE	LRGUK	86	Q96M69
DDVPMETLSSEESCD	CDCA7L	31	Q96GN5
SEDETTPDEEMSSNL	KCNT2	651	Q6UVM3
SISDDDTDSEDELRM	NOL8	296	Q76FK4
MLAESDESGDEESVS	OSBP	186	P22059
SSAMDTSEPAKEEDD	PIPSL	796	A2A3N6
SSKESESALMEDRDE	GAK	811	O14976
ESALMEDRDESEVSD	GAK	816	O14976
SSVMCDSDESDDSDI	CCDC82	186	Q8N4S0
EAVEMEDDDFTASLS	CACNA2D1	956	P54289
DDFETDSDDLIEMTG	CHD2	236	O14647
MEFSELDSDSDERPT	CHD6	1066	Q8TD26
GDFSDVSLEDSTMEE	C19orf44	16	Q9H6X5
SESMDALEEDDLDTC	FRMPD1	606	Q5SYB0
LSEERFVSMETDSDE	ARFGEF3	76	Q5TH69
DVTEELMSDEEDSLN	C14orf93	421	Q9H972
DDLTQDEEDEMSSAS	GON4L	1466	Q3T8J9
DEEDEMSSASEESVL	GON4L	1471	Q3T8J9
SHSSSDSEEEEEEEM	DNAAF8	396	Q8IYS4
EEEEEDEGSMESLTS	CHRM1	276	P11229
SDSSGVIDLTMDDEE	ATF7IP	961	Q6VMQ6
EESSSSDEDDRGEMA	KCMF1	331	Q9P0J7
ESSSVSEDGDSSEMD	BRMS1L	36	Q5PSV4
DSESSSEDVELESMG	DCAF8L1	71	A6NGE4
MEDDEEETTASTLRG	C5orf49	1	A4QMS7
LDDEETAMEQDIDSS	EMSY	1291	Q7Z589
SSAMDTSEPAKEEDD	PSMD4	311	P55036
LSEEMADTLEEGSAS	SASH3	96	O75995
TGEILSESSMENDDE	PPP4R2	391	Q9NY27
SESSMENDDEATEVT	PPP4R2	396	Q9NY27
MEASYESESESESEA	LRRC43	1	Q8N309
SHPFESDTEMSDIDD	PPFIA2	611	O75334
SDTEMSDIDDDDRET	PPFIA2	616	O75334
SDIDDDDRETIFSSM	PPFIA2	621	O75334
ATDESSMADEASIES	GPRASP1	411	Q5JY77
SNSMRSILEEDEEDE	PWWP3A	381	Q2TAK8
EDDLEMSSDASDASG	GTF2F1	211	P35269
ESSRGSDLSDIMEED	RIMBP2	746	O15034
SDLEMPTEEETDTFS	SCN4A	931	P35499
ETRDTMDLESSSSEE	MIA3	396	Q5JRA6
MDLESSSSEEEKEDD	MIA3	401	Q5JRA6
VESEMDEELDDSSEP	RFX3	676	P48380
DRDTTEEESESLDDM	SCHIP1	341	P0DPB3
EEESESLDDMDFLTR	SCHIP1	346	P0DPB3
TDSISAEDSDFEEMG	TAF1L	1106	Q8IZX4
TAAAIMSDTDSDEDS	TAF1	16	P21675
DTDSSSAEDSDFEEM	TAF1	1086	P21675
PFSSSQDEEEIDMDT	TAF2	1036	Q6P1X5
EMSSDSEYDSDDDRT	EIF5B	586	O60841
MEIDSEESESDGSFI	ERCC5	641	P28715
ATMLIHSSESEEEEE	PTPN14	701	Q15678
GMSEATSEAEEEAAT	RETREG2	31	Q8NC44
NSIEDSDMDSDDEIL	SOCS4	221	Q8WXH5
STMENDEESVKEASD	SLC25A36	211	Q96CQ1
MSDSEDSNFSEEEDS	SUPT5H	1	O00267
TEEESESLDDMDFLT	IQCJ-SCHIP1	421	B3KU38
VASIDDSEELMATDS	MYH6	321	P13533
EDSESLAVMTEEGSD	ST18	281	O60284
GSQTESEEESSEMDD	BRMS1	36	Q9HCU9
SMLEDDLQLSDSEDS	AFF1	421	P51825
SSDESSEEDLSAEMT	NCAPD2	1366	Q15021
SEEDLSAEMTEDETP	NCAPD2	1371	Q15021
DEDSMDIPLDLSSSA	TGIF1	146	Q15583
SSSDDDTDVDMEGLR	PBXIP1	146	Q96AQ6
LEGDEESTMLEDSVS	TLN1	411	Q9Y490
ELSKEEEDTDSSEEM	TRPM2	661	O94759
EEDTDSSEEMLALAE	TRPM2	666	O94759
TDSSVEESDFDTMPD	SIDT1	396	Q9NXL6
DEEEYDTDEIDSSSM	TBC1D23	556	Q9NUY8
DTDEIDSSSMSDDDR	TBC1D23	561	Q9NUY8
AMDDDTASEETGSEL	SFMBT2	726	Q5VUG0
DQPSETDHLSMEEED	TPRG1	21	Q6ZUI0
EVSGSMPDSLAEEDD	TECPR2	551	O15040
DTDSHSSEEIDTEEM	SMCO2	241	A6NFE2
SSAMGDSDTTEDEDE	TTLL3	61	Q9Y4R7
DYREKSSDDDEMDSS	ZNF200	176	P98182
DSSLEPDLAEMSLDD	ZSWIM8	611	A7E2V4
EDLSDSDSDEPMLEV	ZBED6	361	P86452
SHEASEDDVDASEPM	ZNF423	871	Q2M1K9
WSTVPTDEEDEMEES	WDR12	216	Q9GZL7
SMDTDPETIRDEEET	ZEB2	1171	O60315
DEEETGDHSMDDSSE	ZEB2	1181	O60315
ESEEHFSEEMESLLD	WDR87	2221	Q6ZQQ6
SEASDSDAMDQSREE	TFAP4	316	Q01664
STESIPVSDEDSDAM	ZMYM3	256	Q14202
PPDVEDMSSSDSDSD	TMEM91	66	Q6ZNR0
LELNDESSDSDEEMT	TMA16	186	Q96EY4
SSPSKEEEEEDDDTM	KMT2D	1346	O14686
VRMESDEDSDSPDSI	KMT2D	4691	O14686
SSDESLDMIDDEILD	PPP1R9A	956	Q9ULJ8