Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC39A10 ABCA8 ABCC6 SLC16A12 ABCB1 SLC38A1 SLC9C1 SLC9A3 SLC9A5 SLC17A1 SLC19A1 SLC38A7 SLC35B1	1.65e-06	477	107	13	GO:0022804
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC39A10 SLC16A12 SLC38A1 SLC9C1 SLC9A3 SLC9A5 SLC17A1 SLC19A1 SLC38A7 SLC35B1	4.36e-06	296	107	10	GO:0015291
GeneOntologyMolecularFunction	peptide hormone binding	CALCR GCGR GLP1R SCTR CALCRL	1.13e-05	55	107	5	GO:0017046
GeneOntologyMolecularFunction	L-glutamine transmembrane transporter activity	SLC38A1 SLC38A7 SLC38A6	1.23e-05	9	107	3	GO:0015186
GeneOntologyMolecularFunction	transporter activity	PIEZO1 TMC6 SLC39A10 ABCA8 ABCC6 SLC16A12 ABCB1 SLC38A1 CPTP SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SV2A SLC19A1 SLC38A7 TRPV4 SLC38A6 SLC35B1	1.47e-05	1289	107	20	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	PIEZO1 TMC6 SLC39A10 ABCA8 ABCC6 SLC16A12 ABCB1 SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SV2A SLC19A1 SLC38A7 TRPV4 SLC38A6 SLC35B1	1.49e-05	1180	107	19	GO:0022857
GeneOntologyMolecularFunction	G protein-coupled receptor activity	HTR2B CALCR OR5I1 CASR GCGR PTGER4 TAS2R9 OR51D1 GLP1R SCTR TAS2R41 C5AR1 CALCRL OR51V1 GNRHR GPR45	1.89e-05	884	107	16	GO:0004930
GeneOntologyMolecularFunction	calcitonin receptor activity	CALCR CALCRL	2.84e-05	2	107	2	GO:0004948
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCA8 ABCC6 ABCB1 SLC19A1	3.19e-05	34	107	4	GO:0042910
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC38A7	3.79e-05	171	107	7	GO:0015081
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9C1 SLC9A3 SLC9A5	5.22e-05	14	107	3	GO:0015386
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCA8 ABCC6 ABCB1	6.49e-05	15	107	3	GO:0008559
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9C1 SLC9A3 SLC9A5	7.96e-05	16	107	3	GO:0015385
GeneOntologyMolecularFunction	glucagon receptor activity	GCGR GLP1R	8.50e-05	3	107	2	GO:0004967
GeneOntologyMolecularFunction	mechanosensitive monoatomic ion channel activity	PIEZO1 TMC6 TRPV4	1.15e-04	18	107	3	GO:0008381
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9C1 SLC9A3 SLC9A5	1.36e-04	19	107	3	GO:0022821
GeneOntologyMolecularFunction	calcitonin family binding	CALCR CALCRL	1.69e-04	4	107	2	GO:0097644
GeneOntologyMolecularFunction	alanine:sodium symporter activity	SLC38A1 SLC38A7	1.69e-04	4	107	2	GO:0015655
GeneOntologyMolecularFunction	calcitonin gene-related peptide receptor activity	CALCR CALCRL	1.69e-04	4	107	2	GO:0001635
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC39A10 SLC16A12 ABCB1 SLC38A1 SLC19A1 SLC38A7 SLC38A6 SLC35B1	1.81e-04	293	107	8	GO:0008514
GeneOntologyMolecularFunction	amide binding	CALCR GCGR CPTP FASN SLC19A1 GLP1R SCTR CALCRL	2.08e-04	299	107	8	GO:0033218
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC39A10 SLC38A1 SLC9C1 SLC9A3 SLC9A5 SLC17A1 SLC19A1 SLC38A7	2.18e-04	301	107	8	GO:0022853
GeneOntologyMolecularFunction	hormone binding	CALCR GCGR GLP1R SCTR CALCRL	2.32e-04	103	107	5	GO:0042562
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	HTR2B CALCR OR5I1 CASR GCGR PTGER4 SLAMF1 TAS2R9 OR51D1 GLP1R SCTR TRPV4 TAS2R41 C5AR1 CALCRL OR51V1 GNRHR GPR45	2.92e-04	1353	107	18	GO:0004888
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	SLC9C1 SLC9A3 SLC9A5	3.98e-04	27	107	3	GO:0051139
GeneOntologyMolecularFunction	NAD+-protein poly-ADP-ribosyltransferase activity	ART4 PARP9 TNKS2	4.45e-04	28	107	3	GO:0003950
GeneOntologyMolecularFunction	NAD+-protein ADP-ribosyltransferase activity	ART4 PARP9 TNKS2	5.47e-04	30	107	3	GO:1990404
GeneOntologyMolecularFunction	calcitonin family receptor activity	CALCR CALCRL	5.87e-04	7	107	2	GO:0097642
GeneOntologyMolecularFunction	mechanosensitive monoatomic cation channel activity	PIEZO1 TRPV4	5.87e-04	7	107	2	GO:0140135
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	CALCR GCGR GLP1R SCTR CALCRL	7.51e-04	133	107	5	GO:0008528
GeneOntologyMolecularFunction	neutral L-amino acid:sodium symporter activity	SLC38A1 SLC38A7	7.80e-04	8	107	2	GO:0005295
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC16A12 ABCB1 SLC38A1 SLC19A1 SLC38A7 SLC38A6	8.75e-04	207	107	6	GO:0046943
GeneOntologyMolecularFunction	antiporter activity	SLC9C1 SLC9A3 SLC9A5 SLC19A1 SLC35B1	8.86e-04	138	107	5	GO:0015297
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC39A10 SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC38A7 TRPV4	8.90e-04	465	107	9	GO:0046873
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC16A12 ABCB1 SLC38A1 SLC19A1 SLC38A7 SLC38A6	8.97e-04	208	107	6	GO:0005342
GeneOntologyMolecularFunction	peptide receptor activity	CALCR GCGR GLP1R SCTR CALCRL	9.45e-04	140	107	5	GO:0001653
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	PIEZO1 TMC6 SLC39A10 SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC19A1 SLC38A7 TRPV4	1.11e-03	793	107	12	GO:0015075
GeneOntologyMolecularFunction	nucleotidyltransferase activity	POLA1 RPAP1 ART4 PARP9 TNKS2	1.36e-03	152	107	5	GO:0016779
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC38A1 SLC38A7 SLC38A6	1.38e-03	41	107	3	GO:0015175
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC9C1 SLC9A3 SLC9A5	1.58e-03	43	107	3	GO:0140828
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA8 ABCC6 ABCB1	2.30e-03	49	107	3	GO:0140359
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	PIEZO1 SLC39A10 SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC38A7 TRPV4	3.00e-03	664	107	10	GO:0008324
GeneOntologyMolecularFunction	alanine transmembrane transporter activity	SLC38A1 SLC38A7	3.25e-03	16	107	2	GO:0022858
GeneOntologyMolecularFunction	pentosyltransferase activity	ART4 PARP9 TNKS2	3.37e-03	56	107	3	GO:0016763
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC39A10 SLC38A1 SLC17A1 SLC38A7	3.86e-03	119	107	4	GO:0015294
GeneOntologyMolecularFunction	glycosyltransferase activity	DPAGT1 DPY19L3 TMTC2 ART4 PARP9 TNKS2	4.58e-03	288	107	6	GO:0016757
GeneOntologyMolecularFunction	sphingolipid transporter activity	ABCB1 CPTP	5.07e-03	20	107	2	GO:0046624
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC39A10 SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC38A7 TRPV4	6.56e-03	627	107	9	GO:0022890
GeneOntologyMolecularFunction	L-amino acid transmembrane transporter activity	SLC38A1 SLC38A7 SLC38A6	6.57e-03	71	107	3	GO:0015179
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	SLC19A1 SLC35B1	6.69e-03	23	107	2	GO:0005346
GeneOntologyMolecularFunction	amino acid:sodium symporter activity	SLC38A1 SLC38A7	6.69e-03	23	107	2	GO:0005283
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC39A10 ABCC6 SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC38A7 TRPV4	7.51e-03	758	107	10	GO:0015318
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC19A1 SLC35B1	8.50e-03	26	107	2	GO:0000295
GeneOntologyMolecularFunction	symporter activity	SLC39A10 SLC38A1 SLC17A1 SLC38A7	8.69e-03	150	107	4	GO:0015293
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R9 TAS2R41	9.15e-03	27	107	2	GO:0033038
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC38A1 SLC17A1 SLC38A7	9.43e-03	81	107	3	GO:0015370
GeneOntologyMolecularFunction	mannosyltransferase activity	DPY19L3 TMTC2	9.82e-03	28	107	2	GO:0000030
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC38A1 SLC38A7 SLC38A6	1.01e-02	83	107	3	GO:0015101
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC38A1 SLC38A7	1.05e-02	29	107	2	GO:0005416
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	SLC19A1 SLC35B1	1.05e-02	29	107	2	GO:0015216
GeneOntologyBiologicalProcess	monoatomic ion transport	ATP6AP1 HTR2B PIEZO1 TMC6 CASR SLC39A10 ABCC6 ABCB1 CD84 SLC38A1 SLC35G1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC19A1 GLP1R SLC38A7 TRPV4 CALCRL STEAP1B	2.12e-06	1374	108	22	GO:0006811
GeneOntologyBiologicalProcess	organic anion transport	CASR SLC39A10 ABCC6 SLC16A12 ABCB1 SLC38A1 CPTP SLC17A1 SV2A SLC19A1 SLC38A7 SLC38A6 SLC35B1	2.99e-06	515	108	13	GO:0015711
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	ATP6AP1 HTR2B PIEZO1 TMC6 CASR SLC39A10 ABCC6 ABCB1 SLC38A1 SLC35G1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC19A1 GLP1R TRPV4 STEAP1B	4.85e-06	1115	108	19	GO:0034220
GeneOntologyBiologicalProcess	glutamine transport	SLC38A1 SLC38A7 SLC38A6	1.63e-05	10	108	3	GO:0006868
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	ATP6AP1 HTR2B TMTC2 WBP2NL CASR SLC39A10 ABCC6 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SV2A GLP1R TRPV4	1.88e-05	705	108	14	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	ATP6AP1 HTR2B TMTC2 WBP2NL CASR SLC39A10 ABCC6 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SV2A GLP1R TRPV4	2.26e-05	717	108	14	GO:0050801
GeneOntologyBiologicalProcess	monoatomic cation transport	ATP6AP1 HTR2B PIEZO1 CASR SLC39A10 CD84 SLC38A1 SLC35G1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 GLP1R SLC38A7 TRPV4 CALCRL STEAP1B	3.02e-05	1157	108	18	GO:0006812
GeneOntologyBiologicalProcess	metal ion transport	HTR2B CASR SLC39A10 CD84 SLC38A1 SLC35G1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 GLP1R SLC38A7 TRPV4 CALCRL STEAP1B	6.33e-05	1000	108	16	GO:0030001
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	ATP6AP1 HTR2B WBP2NL CASR SLC39A10 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SV2A GLP1R TRPV4	8.57e-05	611	108	12	GO:0030003
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	ATP6AP1 HTR2B WBP2NL CASR SLC39A10 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SV2A GLP1R TRPV4	1.01e-04	622	108	12	GO:0006873
GeneOntologyBiologicalProcess	xenobiotic transmembrane transport	ABCA8 ABCC6 SLC19A1	1.27e-04	19	108	3	GO:0006855
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	ATP6AP1 HTR2B WBP2NL CASR SLC39A10 ABCC6 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SV2A GLP1R SCTR TRPV4	1.70e-04	866	108	14	GO:0055082
GeneOntologyBiologicalProcess	cellular homeostasis	ATP6AP1 HTR2B WBP2NL CASR SLC39A10 ABCC6 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SV2A GLP1R SCTR TRPV4 RHOT1	1.80e-04	981	108	15	GO:0019725
GeneOntologyBiologicalProcess	calcium ion homeostasis	HTR2B TMTC2 WBP2NL CASR ABCC6 SLC35G1 SV2A GLP1R TRPV4	2.08e-04	389	108	9	GO:0055074
GeneOntologyBiologicalProcess	import across plasma membrane	SLC39A10 SLC38A1 SLC9C1 SLC9A3 SLC9A5 SLC19A1 TRPV4	2.10e-04	230	108	7	GO:0098739
GeneOntologyBiologicalProcess	carboxylic acid transport	CASR ABCC6 SLC16A12 ABCB1 SLC38A1 SV2A SLC19A1 SLC38A7 SLC38A6	3.07e-04	410	108	9	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	CASR ABCC6 SLC16A12 ABCB1 SLC38A1 SV2A SLC19A1 SLC38A7 SLC38A6	3.18e-04	412	108	9	GO:0015849
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	HTR2B CALCR OR5I1 CASR GCGR PTGER4 TAS2R9 OR51D1 GLP1R TMEM145 NSG1 SCTR TAS2R41 C5AR1 CALCRL OR51V1 GNRHR GPR45	3.22e-04	1395	108	18	GO:0007186
GeneOntologyBiologicalProcess	positive regulation of macrophage chemotaxis	SLAMF1 TRPV4 C5AR1	3.32e-04	26	108	3	GO:0010759
GeneOntologyBiologicalProcess	xenobiotic transport	ABCA8 ABCC6 ABCB1 SLC19A1	3.55e-04	64	108	4	GO:0042908
GeneOntologyBiologicalProcess	sodium ion import across plasma membrane	SLC9C1 SLC9A3 SLC9A5	3.73e-04	27	108	3	GO:0098719
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	ATP6AP1 HTR2B PIEZO1 SLC39A10 SLC38A1 SLC35G1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 GLP1R TRPV4 STEAP1B	4.01e-04	942	108	14	GO:0098655
GeneOntologyBiologicalProcess	inorganic ion homeostasis	ATP6AP1 HTR2B TMTC2 WBP2NL CASR SLC39A10 ABCC6 SLC35G1 SV2A GLP1R TRPV4	4.20e-04	622	108	11	GO:0098771
GeneOntologyBiologicalProcess	vascular process in circulatory system	DDAH1 HTR2B CASR SLC16A12 ABCB1 SLC38A1 SLC19A1 TRPV4	4.57e-04	344	108	8	GO:0003018
GeneOntologyBiologicalProcess	integrin activation	PIEZO1 PTGER4 TLN1	4.62e-04	29	108	3	GO:0033622
GeneOntologyBiologicalProcess	adenylate cyclase-activating G protein-coupled receptor signaling pathway	CALCR GCGR PTGER4 GLP1R SCTR CALCRL	5.10e-04	191	108	6	GO:0007189
GeneOntologyBiologicalProcess	sodium ion transport	SLC38A1 SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 SLC38A7	6.15e-04	275	108	7	GO:0006814
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	DPAGT1 DPY19L3 ATP6AP1 DNAJC16 PIEZO1 TMC6 TMEM39B TMTC2 PIGU ABCC6 DDOST CPTP ERGIC1 SLC35G1 STS RNF103 NSG1 PIGW SDR16C5 SLC35B1	1.00e-05	1327	106	20	GO:0042175
GeneOntologyCellularComponent	endoplasmic reticulum membrane	DPAGT1 DPY19L3 ATP6AP1 DNAJC16 PIEZO1 TMC6 TMEM39B TMTC2 PIGU ABCC6 DDOST ERGIC1 SLC35G1 STS RNF103 NSG1 PIGW SDR16C5 SLC35B1	2.46e-05	1293	106	19	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	DPAGT1 DPY19L3 ATP6AP1 DNAJC16 PIEZO1 TMC6 TMEM39B TMTC2 PIGU ABCC6 DDOST ERGIC1 SLC35G1 STS RNF103 NSG1 PIGW SDR16C5 SLC35B1	2.62e-05	1299	106	19	GO:0098827
GeneOntologyCellularComponent	apical plasma membrane	CASR SLC39A10 ABCC6 ABCB1 SLC38A1 SLC9A3 ZMYND10 SLC17A1 SLC19A1 TRPV4	1.86e-04	487	106	10	GO:0016324
GeneOntologyCellularComponent	apical part of cell	CASR SLC39A10 ABCC6 ABCB1 SLC38A1 SLC9A3 ZMYND10 SLC17A1 SLC19A1 TRPV4 C5AR1	2.09e-04	592	106	11	GO:0045177
GeneOntologyCellularComponent	calcitonin family receptor complex	CALCR CALCRL	2.52e-04	5	106	2	GO:1903439
GeneOntologyCellularComponent	external side of apical plasma membrane	ABCB1 SLC38A1	3.77e-04	6	106	2	GO:0098591
GeneOntologyCellularComponent	basolateral plasma membrane	CASR ABCA8 ABCC6 SLC16A12 SLC38A1 SLC19A1 C5AR1	1.23e-03	320	106	7	GO:0016323
GeneOntologyCellularComponent	G protein-coupled receptor complex	CALCR CALCRL	1.36e-03	11	106	2	GO:0097648
Domain	HormR	CALCR GCGR GLP1R SCTR CALCRL	2.36e-07	25	104	5	SM00008
Domain	HRM	CALCR GCGR GLP1R SCTR CALCRL	4.31e-07	28	104	5	PF02793
Domain	GPCR_2_secretin-like_CS	CALCR GCGR GLP1R SCTR CALCRL	1.19e-06	34	104	5	IPR017983
Domain	G_PROTEIN_RECEP_F2_1	CALCR GCGR GLP1R SCTR CALCRL	2.74e-06	40	104	5	PS00649
Domain	GPCR_2_extracellular_dom	CALCR GCGR GLP1R SCTR CALCRL	2.74e-06	40	104	5	IPR001879
Domain	G_PROTEIN_RECEP_F2_3	CALCR GCGR GLP1R SCTR CALCRL	2.74e-06	40	104	5	PS50227
Domain	G_PROTEIN_RECEP_F2_2	CALCR GCGR GLP1R SCTR CALCRL	8.44e-06	50	104	5	PS00650
Domain	7tm_2	CALCR GCGR GLP1R SCTR CALCRL	8.44e-06	50	104	5	PF00002
Domain	GPCR_2_secretin-like	CALCR GCGR GLP1R SCTR CALCRL	2.08e-05	60	104	5	IPR000832
Domain	GPCR_2-like	CALCR GCGR GLP1R SCTR CALCRL	2.08e-05	60	104	5	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	CALCR GCGR GLP1R SCTR CALCRL	2.26e-05	61	104	5	PS50261
Domain	Cation/H_exchanger_CPA1	SLC9C1 SLC9A3 SLC9A5	2.68e-05	11	104	3	IPR018422
Domain	GPCR_2_GLP1/glucagon_rcpt	GCGR GLP1R	3.07e-05	2	104	2	IPR003290
Domain	GCPR_2_calcitonin_rcpt_fam	CALCR CALCRL	3.07e-05	2	104	2	IPR003287
Domain	Na/H_exchanger_3/5	SLC9A3 SLC9A5	3.07e-05	2	104	2	IPR018410
Domain	Na_H_Exchanger	SLC9C1 SLC9A3 SLC9A5	5.84e-05	14	104	3	PF00999
Domain	Cation/H_exchanger	SLC9C1 SLC9A3 SLC9A5	5.84e-05	14	104	3	IPR006153
Domain	Aa_trans	SLC38A1 SLC38A7 SLC38A6	1.08e-04	17	104	3	PF01490
Domain	AA_transpt_TM	SLC38A1 SLC38A7 SLC38A6	1.08e-04	17	104	3	IPR013057
Domain	WGR_domain	ART4 PARP9 TNKS2	3.12e-04	24	104	3	IPR008893
Domain	NaH_exchanger	SLC9A3 SLC9A5	1.08e-03	9	104	2	IPR004709
Domain	ABC_tran	ABCA8 ABCC6 ABCB1	2.42e-03	48	104	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA8 ABCC6 ABCB1	2.42e-03	48	104	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCA8 ABCC6 ABCB1	2.57e-03	49	104	3	PS00211
Domain	ABC_transporter-like	ABCA8 ABCC6 ABCB1	2.72e-03	50	104	3	IPR003439
Domain	PKS_ER	TP53I3 FASN	3.50e-03	16	104	2	SM00829
Domain	PKS_ER	TP53I3 FASN	3.50e-03	16	104	2	IPR020843
Domain	Poly(ADP-ribose)pol_cat_dom	PARP9 TNKS2	3.95e-03	17	104	2	IPR012317
Domain	PARP_CATALYTIC	PARP9 TNKS2	3.95e-03	17	104	2	PS51059
Domain	PARP	PARP9 TNKS2	3.95e-03	17	104	2	PF00644
Domain	-	PARP9 TNKS2	3.95e-03	17	104	2	3.90.228.10
Domain	ADH_zinc_N	TP53I3 FASN	4.94e-03	19	104	2	PF00107
Domain	ADH_C	TP53I3 FASN	4.94e-03	19	104	2	IPR013149
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	CALCR GCGR GLP1R SCTR CALCRL	1.56e-07	24	76	5	M39643
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	CALCR GCGR GLP1R SCTR CALCRL	1.56e-07	24	76	5	MM15992
Pathway	WP_GPCRS_NONODORANT	HTR2B CALCR CASR GCGR PTGER4 GLP1R SCTR TAS2R41 C5AR1 CALCRL GNRHR	1.70e-07	266	76	11	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	HTR2B CALCR CASR GCGR PTGER4 TAS2R9 GLP1R SCTR TAS2R41 C5AR1 CALCRL GNRHR	6.29e-06	463	76	12	M507
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	CALCR GCGR PTGER4 GLP1R SCTR CALCRL GPR45	1.16e-05	143	76	7	MM15055
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	HTR2B CALCR GCGR PTGER4 GLP1R SCTR C5AR1 CALCRL GNRHR	1.49e-05	272	76	9	M13380
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	CALCR GCGR GLP1R SCTR CALCRL	1.73e-05	60	76	5	MM14964
Pathway	REACTOME_GPCR_LIGAND_BINDING	HTR2B CALCR CASR GCGR PTGER4 GLP1R SCTR TAS2R41 C5AR1 CALCRL GNRHR	1.80e-05	430	76	11	MM15160
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	CALCR GCGR PTGER4 GLP1R SCTR CALCRL GPR45	2.13e-05	157	76	7	M4904
Pathway	REACTOME_SIGNALING_BY_GPCR	HTR2B CALCR CASR GCGR PTGER4 TAS2R9 GLP1R SCTR TAS2R41 C5AR1 CALCRL GNRHR GPR45	8.67e-05	702	76	13	M746
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ATP6AP1 SLC39A10 ABCA8 ABCC6 ABCB1 SLC38A1 CPTP SLC9C1 SLC9A3 SLC9A5 NALCN SLC17A1 TRPV4	1.39e-04	736	76	13	M27287
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	CALCR GCGR GLP1R SCTR CALCRL	1.51e-04	94	76	5	M797
Pathway	REACTOME_SIGNALING_BY_GPCR	HTR2B CALCR CASR GCGR PTGER4 GLP1R SCTR TAS2R41 C5AR1 CALCRL GNRHR GPR45	1.63e-04	646	76	12	MM14962
Pathway	WP_EFFECTS_OF_MFN2_MUTATION	KIF1B DYNC2I1 RHOT1	2.81e-04	24	76	3	M48308
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GCGR GLP1R SCTR	7.31e-04	33	76	3	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GCGR GLP1R SCTR	7.31e-04	33	76	3	M10322
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ATP6AP1 ABCA8 ABCC6 ABCB1 SLC38A1 CPTP SLC9A3 SLC9A5 NALCN SLC17A1 TRPV4	1.01e-03	681	76	11	MM14985
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A3 SLC9A5	1.01e-03	9	76	2	M27337
Pathway	REACTOME_SODIUM_PROTON_EXCHANGERS	SLC9A3 SLC9A5	1.01e-03	9	76	2	MM15079
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	CASR TAS2R9 TAS2R41	1.20e-03	39	76	3	M793
Pathway	REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS	CALCR CALCRL	1.26e-03	10	76	2	M27332
Pathway	REACTOME_CALCITONIN_LIKE_LIGAND_RECEPTORS	CALCR CALCRL	1.26e-03	10	76	2	MM15064
Pathway	KEGG_ABC_TRANSPORTERS	ABCA8 ABCC6 ABCB1	1.70e-03	44	76	3	M11911
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	HTR2B CALCR CASR GCGR GLP1R SCTR C5AR1 CALCRL GNRHR	1.37e-08	200	108	9	18240029
Pubmed	Endothelial Restoration of Receptor Activity-Modifying Protein 2 Is Sufficient to Rescue Lethality, but Survivors Develop Dilated Cardiomyopathy.	CALCR CASR GCGR CALCRL	2.85e-08	11	108	4	27402918
Pubmed	Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation.	CALCR CASR GCGR CALCRL	6.15e-08	13	108	4	28727763
Pubmed	Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.	CALCR GCGR PTGER4 GLP1R SCTR CALCRL	8.69e-08	70	108	6	12036966
Pubmed	Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors.	CALCR GLP1R SCTR	3.44e-06	10	108	3	15670850
Pubmed	Design and preparation of the class B G protein-coupled receptors GLP-1R and GCGR for 19 F-NMR studies in solution.	GCGR GLP1R	9.55e-06	2	108	2	33369025
Pubmed	Localization of a (CA)n repeat in glucagon-like peptide-1 receptor gene (Glp1r) to proximal mouse chromosome 17 and its linkage to other markers.	GCGR GLP1R	9.55e-06	2	108	2	7613039
Pubmed	The roles of mechanosensitive ion channels and associated downstream MAPK signaling pathways in PDLC mechanotransduction.	PIEZO1 TRPV4	9.55e-06	2	108	2	32323761
Pubmed	Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents.	GCGR GLP1R	9.55e-06	2	108	2	23203689
Pubmed	Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel.	CASR TRPV4	9.55e-06	2	108	2	28951460
Pubmed	[Involvement of the Piezo1 and TRPV4 stretch-activated channels in pulmonary hypertension].	PIEZO1 TRPV4	9.55e-06	2	108	2	35151521
Pubmed	Glucagon-like peptide 1/glucagon receptor dual agonism reverses obesity in mice.	GCGR GLP1R	9.55e-06	2	108	2	19602537
Pubmed	Activation of calcitonin receptor and calcitonin receptor-like receptor by membrane-anchored ligands.	CALCR CALCRL	9.55e-06	2	108	2	19903822
Pubmed	Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.	GCGR GLP1R	9.55e-06	2	108	2	27226600
Pubmed	Association of MDR1 C3435T and RFC1 G80A polymorphisms with methotrexate toxicity and response in Jordanian rheumatoid arthritis patients.	ABCB1 SLC19A1	9.55e-06	2	108	2	25074866
Pubmed	Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.	PIEZO1 TRPV4	9.55e-06	2	108	2	37349903
Pubmed	Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression.	PIEZO1 TRPV4	9.55e-06	2	108	2	37175575
Pubmed	Functional role for Piezo1 in stretch-evoked Ca²⁺ influx and ATP release in urothelial cell cultures.	PIEZO1 TRPV4	9.55e-06	2	108	2	24759099
Pubmed	PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation.	PIEZO1 TRPV4	9.55e-06	2	108	2	31597314
Pubmed	Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.	PIEZO1 TRPV4	9.55e-06	2	108	2	28135189
Pubmed	Ligand-Receptor Interactions and Machine Learning in GCGR and GLP-1R Drug Discovery.	GCGR GLP1R	9.55e-06	2	108	2	33920024
Pubmed	Differential effects of oxyntomodulin and GLP-1 on glucose metabolism.	GCGR GLP1R	9.55e-06	2	108	2	22621866
Pubmed	Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in mice.	PIEZO1 TRPV4	9.55e-06	2	108	2	35451372
Pubmed	Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress.	PIEZO1 TRPV4	9.55e-06	2	108	2	33298523
Pubmed	Tissue-specific and glucose-dependent expression of receptor genes for glucagon and glucagon-like peptide-1 (GLP-1).	GCGR GLP1R	9.55e-06	2	108	2	9105899
Pubmed	The CaSR/TRPV4 coupling mediates pro-inflammatory macrophage function.	CASR TRPV4	9.55e-06	2	108	2	36606511
Pubmed	Functional Expression of Mechanosensitive Piezo1/TRPV4 Channels in Mouse Osteoblasts.	PIEZO1 TRPV4	9.55e-06	2	108	2	36792153
Pubmed	Piezo1 channels mediate trabecular meshwork mechanotransduction and promote aqueous fluid outflow.	PIEZO1 TRPV4	9.55e-06	2	108	2	33226641
Pubmed	Mouse Samd9l is not a functional paralogue of the human SAMD9, the gene mutated in normophosphataemic familial tumoral calcinosis.	ABCC6 SAMD9L	9.55e-06	2	108	2	22716256
Pubmed	Functional consequences of glucagon-like peptide-1 receptor cross-talk and trafficking.	GCGR GLP1R	9.55e-06	2	108	2	25451942
Pubmed	Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects.	SLC38A1 SLC38A7 SLC38A6	1.29e-05	15	108	3	23506890
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	DNAJC16 PIEZO1 PIGU DDOST ERGIC1 ZMYND10 CLK2 TRPV4 RHOT1	2.67e-05	499	108	9	22810586
Pubmed	Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling.	GCGR GLP1R	2.86e-05	3	108	2	22933116
Pubmed	Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1-/- mice.	CASR TRPV4	2.86e-05	3	108	2	31603369
Pubmed	Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice.	CALCR CALCRL	2.86e-05	3	108	2	25010197
Pubmed	Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.	GCGR GLP1R	2.86e-05	3	108	2	15300587
Pubmed	The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium.	PIEZO1 TRPV4	2.86e-05	3	108	2	29632308
Pubmed	Expression of the calcitonin receptor, calcitonin receptor-like receptor, and receptor activity modifying proteins during osteoclast differentiation.	CALCR CALCRL	2.86e-05	3	108	2	18384073
Pubmed	β Cell tone is defined by proglucagon peptides through cAMP signaling.	GCGR GLP1R	2.86e-05	3	108	2	30720465
Pubmed	Differential expression of glucagon and glucagon-like peptide 1 receptors in mouse pancreatic alpha and beta cells in two models of alpha cell hyperplasia.	GCGR GLP1R	2.86e-05	3	108	2	19647035
Pubmed	The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice.	GCGR GLP1R	2.86e-05	3	108	2	29107282
Pubmed	Cell contact and Nf2/Merlin-dependent regulation of TEAD palmitoylation and activity.	TEAD1 FASN	2.86e-05	3	108	2	31043565
Pubmed	TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation.	PIEZO1 TRPV4	2.86e-05	3	108	2	31999644
Pubmed	Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome.	ABCC6 ABCB1	2.86e-05	3	108	2	27287205
Pubmed	Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents.	GCGR GLP1R	2.86e-05	3	108	2	30150304
Pubmed	Insulin Secretion Depends on Intra-islet Glucagon Signaling.	GCGR GLP1R	2.86e-05	3	108	2	30380405
Pubmed	Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes.	GCGR GLP1R	2.86e-05	3	108	2	24939431
Pubmed	Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.	GCGR GLP1R	2.86e-05	3	108	2	32554468
Pubmed	Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors.	SLAMF1 CD84	2.86e-05	3	108	2	25926831
Pubmed	Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis.	GCGR GLP1R	2.86e-05	3	108	2	21540554
Pubmed	Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse.	GCGR GLP1R	2.86e-05	3	108	2	8156917
Pubmed	Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions.	CALCR CASR	2.86e-05	3	108	2	36088585
Pubmed	TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis.	TM7SF3 TEAD1	2.86e-05	3	108	2	38670107
Pubmed	CRISPR-Mediated Slamf1Δ/Δ Slamf5Δ/Δ Slamf6Δ/Δ Triple Gene Disruption Reveals NKT Cell Defects but Not T Follicular Helper Cell Defects.	SLAMF1 CD84	2.86e-05	3	108	2	27223891
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	DDOST FARSA FASN CSE1L FANCI TLN1	3.62e-05	197	108	6	31620119
Pubmed	Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.	ABCB1 SLC38A1 SLC19A1	3.72e-05	21	108	3	23137377
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DNAJC16 KIF1B FAM91A1 SLC39A10 RPAP1 SV2A TLN1 OGFOD1	4.17e-05	407	108	8	12693553
Pubmed	A spectrum of ABCC6 mutations is responsible for pseudoxanthoma elasticum.	ABCC6 ABCB1	5.71e-05	4	108	2	11536079
Pubmed	Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.	SLAMF1 CD84	5.71e-05	4	108	2	11414741
Pubmed	Molecular physiology of vertebrate Na+/H+ exchangers.	SLC17A1 SLC19A1	5.71e-05	4	108	2	9016300
Pubmed	A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.	GCGR GLP1R	5.71e-05	4	108	2	25485909
Pubmed	Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling.	SLAMF1 CD84	5.71e-05	4	108	2	16037392
Pubmed	Do SNPs in folate pharmacokinetic pathway alter levels of intracellular methotrexate polyglutamates and affect response? A prospective study in Indian patients.	ABCB1 SLC19A1	5.71e-05	4	108	2	30022368
Pubmed	The major brain isoform of kif1b lacks the putative mitochondria-binding domain.	TNFRSF9 KIF1B	5.71e-05	4	108	2	10341097
Pubmed	ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients.	ABCB1 SLC19A1	5.71e-05	4	108	2	17181924
Pubmed	Na+/H+ exchangers of mammalian cells.	SLC17A1 SLC19A1	5.71e-05	4	108	2	9278382
Pubmed	CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A.	SLAMF1 CD84	5.71e-05	4	108	2	11313386
Pubmed	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.	GAPVD1 PIEZO1 SLC39A10 SLC38A1 SLC19A1	5.95e-05	132	108	5	26439863
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	GAPVD1 FAM91A1 DDOST SLC38A1 FARSA FASN CSE1L TLN1	8.28e-05	449	108	8	31732153
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	CALCR CASR SLC9A3 SLC19A1 CALCRL	8.69e-05	143	108	5	20424473
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DPY19L3 ATP6AP1 DNAJC16 PIEZO1 TMTC2 SLC39A10 PIGU DDOST SLC38A1 ERGIC1 STS FANCI TMEM131	9.19e-05	1201	108	13	35696571
Pubmed	Interaction of genes from influx-metabolism-efflux pathway and their influence on methotrexate efficacy in rheumatoid arthritis patients among Indians.	ABCB1 SLC19A1	9.50e-05	5	108	2	19093297
Pubmed	miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4.	HTR2B TRPV4	9.50e-05	5	108	2	36049541
Pubmed	Application of high-resolution melting to large-scale, high-throughput SNP genotyping: a comparison with the TaqMan method.	ABCB1 SLC19A1	9.50e-05	5	108	2	20371868
Pubmed	Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure.	PIEZO1 CALCRL	9.50e-05	5	108	2	31205027
Pubmed	Non-coding RNA Neat1 and Abhd11os expressions are dysregulated in medium spiny neurons of Huntington disease model mice.	SMIM10L2A SMIM10L2B	9.50e-05	5	108	2	30391555
Pubmed	Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.	PIEZO1 TRPV4	9.50e-05	5	108	2	28060940
Pubmed	Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP.	SLAMF1 CD84	9.50e-05	5	108	2	11389028
Pubmed	Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients.	SLAMF1 CD84	1.42e-04	6	108	2	11477068
Pubmed	Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.	ABCB1 SLC19A1	1.42e-04	6	108	2	18607581
Pubmed	GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7.	GCGR GLP1R	1.42e-04	6	108	2	25738454
Pubmed	T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP.	SLAMF1 CD84	1.42e-04	6	108	2	28904129
Pubmed	SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.	SLAMF1 CD84	1.42e-04	6	108	2	24795728
Pubmed	Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.	SLAMF1 CD84	1.42e-04	6	108	2	11689425
Pubmed	Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche.	CALCR CALCRL	1.99e-04	7	108	2	29795344
Pubmed	Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins.	CALCR CALCRL	1.99e-04	7	108	2	14722252
Pubmed	Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium.	SLC9A3 SLC9A5	1.99e-04	7	108	2	12576672
Pubmed	Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling.	CALCR CALCRL	1.99e-04	7	108	2	10882736
Pubmed	NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos.	SLC9A3 SLC9A5	1.99e-04	7	108	2	23677982
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	ATP6AP1 DNAJC16 SLC39A10 PIGU SLC38A1	2.29e-04	176	108	5	28692057
Pubmed	Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein.	TNFRSF9 SLC39A10 LINS1 PARP9	2.54e-04	98	108	4	23898208
Pubmed	Genetic susceptibility to childhood acute lymphoblastic leukemia shows protection in Malay boys: results from the Malaysia-Singapore ALL Study Group.	ABCB1 SLC19A1	2.64e-04	8	108	2	19651439
Pubmed	MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.	FASN TLN1	2.64e-04	8	108	2	34131310
Pubmed	Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis.	PIEZO1 TRPV4	2.64e-04	8	108	2	34624205
Pubmed	Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta.	KIF1B SV2A	2.64e-04	8	108	2	11389829
Pubmed	The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2).	SLAMF1 CD84	2.64e-04	8	108	2	12621057
Pubmed	Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.	SLAMF1 CD84	2.64e-04	8	108	2	15589166
Pubmed	Area Postrema Cell Types that Mediate Nausea-Associated Behaviors.	CALCR GLP1R	2.64e-04	8	108	2	33278342
Pubmed	The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity.	DTX3 PARP9	2.64e-04	8	108	2	12670957
Pubmed	Glucagon regulates hepatic kisspeptin to impair insulin secretion.	GCGR GLP1R	2.64e-04	8	108	2	24703698
GeneFamily	Solute carriers	SLC39A10 SLC16A12 SLC38A1 SLC35G1 SLC9C1 SLC9A3 SLC9A5 SLC17A1 SLC19A1 SLC38A7 SLC38A6 SLC35B1	1.02e-07	395	77	12	752
GeneFamily	Glucagon receptor family	GCGR GLP1R SCTR	1.47e-06	6	77	3	269
GeneFamily	Calcitonin receptors	CALCR CALCRL	1.79e-05	2	77	2	265
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP9 TNKS2	2.34e-03	17	77	2	684
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGU PIGW	3.57e-03	21	77	2	680
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 TMTC2 ADTRP TSPAN5 ABCB1 SLC38A1 TRPV4	3.75e-07	187	108	7	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	ASK454-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DPAGT1 POLA1 SLC39A10 TSPAN5 RNF103 EEF1AKMT2 TNKS2	4.03e-07	189	108	7	316c857dec9383823e09f966bca62d52d933b141
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4 C5AR1	5.15e-06	180	108	6	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	6.81e-06	189	108	6	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 ADTRP TSPAN5 SLC38A1 SLC9C1 TRPV4	6.81e-06	189	108	6	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 TM7SF3 TSPAN5 SLC38A1 SLC9C1 TRPV4	7.90e-06	194	108	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO1 TMTC2 TSPAN5 SLC38A1 SLC9C1 TRPV4	7.90e-06	194	108	6	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	TCGA-Stomach-Primary_Tumor\|TCGA-Stomach / Sample_Type by Project: Shred V9	FAM91A1 SLC39A10 CSE1L FANCI SLC38A7 PIGW	9.13e-06	199	108	6	38f1f612b29feb868322999ceeda78e52447ec4f
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma\|TCGA-Stomach / Sample_Type by Project: Shred V9	FAM91A1 SLC39A10 CSE1L FANCI SLC38A7 PIGW	9.13e-06	199	108	6	b10698aee2e6c17bc559eb4f723024141f914b90
ToppCell	facs-Aorta-Heart-24m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PYROXD2 SERINC2 SLC38A1 SLC17A1 AADAT	3.47e-05	152	108	5	1da25f913b0fb167f66e539aef509ca44893a878
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PYROXD2 SERINC2 SLC38A1 SLC17A1 AADAT	3.47e-05	152	108	5	254f92d9e6c9c6404f3875dd54d655af87854b14
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 TMTC2 ADTRP TSPAN5 TRPV4	3.93e-05	156	108	5	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CALCR MAN1C1 ADTRP TSPAN5 SLC38A1	4.17e-05	158	108	5	debebc8534a80e5500051f6fd352dc201585968d
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD84 LINS1 C5AR1 GPR45 SMIM10L2B	4.30e-05	159	108	5	f7803f7b4e0379ae8256ec53110833bedee7db98
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD84 LINS1 C5AR1 GPR45 SMIM10L2B	4.30e-05	159	108	5	6e2d38e78d2ef7803e8bb154b5c788bf62a41045
ToppCell	droplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1C1 PTGER4 TRRAP OGFOD1 C5AR1	6.08e-05	171	108	5	7ca404539344e14dcd90c746c9122f713a7db78b
ToppCell	droplet-Lung-nan-18m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1C1 PTGER4 TRRAP OGFOD1 C5AR1	6.08e-05	171	108	5	ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCell	Endothelial-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	HTR2B TSPAN5 ART4 SV2A CALCRL	6.25e-05	172	108	5	d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 ABCC6 SLC16A12 SLC17A1 TRPV4	6.42e-05	173	108	5	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH1 HTR2B SLC16A12 NSG1 CALCRL	6.96e-05	176	108	5	460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DDAH1 SLC35G1 FASN SCTR SDR16C5	7.15e-05	177	108	5	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DDAH1 SLC35G1 FASN SCTR SDR16C5	7.15e-05	177	108	5	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 TMTC2 ADTRP TSPAN5 SLC38A1	7.15e-05	177	108	5	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CASR GCGR SLC16A12 SLC9A3 SCTR	7.54e-05	179	108	5	d0fa700648db8ce76a8aa689879a25048299fa40
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CASR GCGR SLC16A12 SLC9A3 SCTR	7.54e-05	179	108	5	2e49b215b71438400aebb483f2c2c08d5e956961
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASR GCGR SLC16A12 SLC9A3 SCTR	7.74e-05	180	108	5	eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASR GCGR SLC16A12 SLC9A3 SCTR	7.74e-05	180	108	5	a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 TMTC2 ABCB1 SLC38A1 TRPV4	7.95e-05	181	108	5	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 TMTC2 TSPAN5 SLC38A1 TRPV4	7.95e-05	181	108	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CASR GCGR SLC16A12 SLC9A3 SCTR	8.16e-05	182	108	5	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	PCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TNFRSF9 PTGER4 SLAMF1 ABCB1 SLC38A1	8.59e-05	184	108	5	33db879e629821fb75684e60f8f0749cf9623bdd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	8.81e-05	185	108	5	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	SERINC2 ADTRP DNASE2B SAMD9L SLC38A6	9.04e-05	186	108	5	ddfadd43efeac3b3e6b7062590cc2b8f2f2db2ab
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 ABCC6 SLC16A12 SLC17A1 TRPV4	9.27e-05	187	108	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DDAH1 ABCC6 FASN SCTR SDR16C5	9.27e-05	187	108	5	11670a85db87cbb3e78022a589632173604b0940
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DDAH1 ABCC6 FASN SCTR SDR16C5	9.27e-05	187	108	5	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	9.27e-05	187	108	5	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH1 HTR2B TMTC2 NSG1 CALCRL	9.50e-05	188	108	5	db0652f000d459493321b53239326706eace598c
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TNFRSF9 OAZ2 CD84 DNASE2B C5AR1	9.50e-05	188	108	5	fcf1bebef7aa81b4a11c1f9e4319339c290ecd22
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAN1C1 ADTRP TSPAN5 SLC38A1 TRPV4	9.50e-05	188	108	5	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	TEAD1 FASN SLC9C1 SCTR SDR16C5	9.50e-05	188	108	5	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	9.74e-05	189	108	5	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	droplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH1 HTR2B TMTC2 NSG1 CALCRL	9.74e-05	189	108	5	7b6cb745c0a637d6addc105a79059ed488fced39
ToppCell	368C-Myeloid-Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	ATP6AP1 SERINC2 ADTRP DNASE2B SAMD9L	9.74e-05	189	108	5	e62355be0d136e2b7c739848022292e9c6af7392
ToppCell	PCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TNFRSF9 ADTRP SLAMF1 ABCB1 SLC38A1	9.74e-05	189	108	5	78dcda09109a5cfb04ba069f16ec80987b3ad432
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLAMF1 SLC38A1 LINS1 SLC9A3 FANCI	9.99e-05	190	108	5	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLAMF1 SLC38A1 LINS1 SLC9A3 FANCI	9.99e-05	190	108	5	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLAMF1 SLC38A1 LINS1 SLC9A3 FANCI	9.99e-05	190	108	5	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 SLC38A1 SLC9C1 TRPV4	1.02e-04	191	108	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMC6 SLAMF1 TSPAN5 CD84 SLC38A1	1.02e-04	191	108	5	1a2d5fec2bea96da2154b0aed252f1bb35102f6e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTGER4 SLAMF1 CD84 SLC38A1 NSG1	1.02e-04	191	108	5	142f98cabf8737b28369315b3d7a0797ded88e03
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMC6 SLAMF1 TSPAN5 CD84 SLC38A1	1.02e-04	191	108	5	326b4541069efedc8ab409f85bb11f77346dda90
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	1.05e-04	192	108	5	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 ADTRP TSPAN5 SLC38A1 TRPV4	1.05e-04	192	108	5	40f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCell	COVID-19-lung-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PIEZO1 TSPAN5 SLC38A1 ART4 CALCRL	1.05e-04	192	108	5	cbe57cda44232b183821ac633b60a2668265e616
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASR GCGR SLC16A12 SLC9A3 SCTR	1.05e-04	192	108	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	moderate-Lymphoid-CTL\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMC6 PTGER4 ABCB1 CD84 SLC38A1	1.07e-04	193	108	5	3fce0807631811da1cff5ca9db23ff1ad36020e7
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DDAH1 ABCC6 FASN SCTR SDR16C5	1.07e-04	193	108	5	8646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCell	368C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ATP6AP1 ADTRP DNASE2B SAMD9L SLC38A6	1.07e-04	193	108	5	c8883731567d0def96e4105dc34b995d1275ddf4
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMTC2 SERINC2 SLAMF1 ABCB1 CALCRL	1.07e-04	193	108	5	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	1.10e-04	194	108	5	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMTC2 TSPAN5 ABCB1 SLC38A1 TRPV4	1.10e-04	194	108	5	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 TP53I3 TMTC2 STS RPAP1	1.10e-04	194	108	5	88db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO1 TP53I3 TMTC2 STS RPAP1	1.10e-04	194	108	5	a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TNFRSF9 PTGER4 ABCB1 SLC38A1 RRN3P1	1.13e-04	195	108	5	0a72b8446399807ace5b6c72f865bb40dbd9e92d
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLAMF1 TSPAN5 ABCB1 SLC38A1 NSG1	1.18e-04	197	108	5	9acf6719126ca335f584811a72b46af485d67437
ToppCell	BAL-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SLAMF1 TSPAN5 ABCB1 SLC38A1 NSG1	1.18e-04	197	108	5	82eab092d075507889fe1d8845c754a7f0bed30a
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PIEZO1 TMC6 PTGER4 CD84 C5AR1	1.24e-04	199	108	5	4ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PIEZO1 TMC6 PTGER4 CD84 C5AR1	1.24e-04	199	108	5	3ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTGER4 SLAMF1 ABCB1 CD84 SLC38A1	1.27e-04	200	108	5	dfdfad881c114e1bc9a64b411e1b00fb37cc859b
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATP6AP1 ADTRP ART4 C5AR1 SLC38A6	1.27e-04	200	108	5	2cca77b2c9d829daa674a844e068f2b083e90d6e
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTGER4 SLAMF1 TSPAN5 ABCB1 SLC38A1	1.27e-04	200	108	5	20ffb3436d08042f77800513e6ddb3bbc38ae6fe
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-NK_CD56bright\|Leuk-UTI / Disease, condition lineage and cell class	PYROXD2 SLC39A10 ABCB1 SLC38A1 ART4	1.27e-04	200	108	5	1d152e9e0170b4efe42d87b8c09e3ca3ef2ae5d7
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PYROXD2 SLC35G1 SLC9C1 SLC9A5	1.77e-04	115	108	4	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PYROXD2 SLC35G1 SLC9C1 SLC9A5	1.77e-04	115	108	4	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PYROXD2 SLC35G1 SLC9C1 SLC9A5	1.77e-04	115	108	4	c67145d3cd9243994a141749b426ff2a6dcc8d93
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A3 SLC9A5	1.22e-04	5	104	2	DOID:585 (implicated_via_orthology)
Disease	urinary metabolite measurement	DDAH1 DNAJC16 PYROXD2 SLC38A1 SLC17A1 DNPEP	2.37e-04	245	104	6	EFO_0005116
Disease	SLAM family member 5 measurement	SLAMF1 CD84	2.55e-04	7	104	2	EFO_0020741
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CALCRL	2.55e-04	7	104	2	DOID:0050580 (is_implicated_in)
Disease	asymmetrical dimethylarginine measurement	DDAH1 PYROXD2	3.40e-04	8	104	2	EFO_0006522
Disease	Colorectal Carcinoma	DPAGT1 TNFRSF9 ABCA8 ABCC6 ABCB1 CSE1L RPAP1 SLC19A1 MS4A5	8.55e-04	702	104	9	C0009402
Disease	Hypercalcemia	CALCR CASR	9.36e-04	13	104	2	C0020437
Disease	Milk-Alkali Syndrome	CALCR CASR	9.36e-04	13	104	2	C0026141
Disease	ulcerative colitis (is_implicated_in)	PTGER4 ABCB1	1.62e-03	17	104	2	DOID:8577 (is_implicated_in)
Disease	Charcot-Marie-Tooth disease type 2	KIF1B TRPV4	1.62e-03	17	104	2	cv:C0270914
Disease	Benign Neoplasm	ABCB1 FASN GLP1R	1.81e-03	68	104	3	C0086692
Disease	Neoplasms	ABCB1 FASN GLP1R	1.81e-03	68	104	3	C0027651
Disease	Phenyllactate (PLA) measurement	SLC17A1 SLC38A7	2.02e-03	19	104	2	EFO_0021662
Disease	Drugs used in diabetes use measurement	CASR PIGU RPAP1 GLP1R SCTR	2.13e-03	255	104	5	EFO_0009924
Disease	end stage renal disease (implicated_via_orthology)	PTGER4 ABCB1	2.24e-03	20	104	2	DOID:783 (implicated_via_orthology)
Disease	Colorectal Neoplasms	DPAGT1 ABCA8 ABCC6 ABCB1 SLC19A1	3.04e-03	277	104	5	C0009404
Disease	malaria (is_implicated_in)	ABCB1 SLC19A1	3.23e-03	24	104	2	DOID:12365 (is_implicated_in)
Disease	Drug toxicity	HTR2B ABCB1 SLC19A1	3.30e-03	84	104	3	C0013221
Disease	Adverse reaction to drug	HTR2B ABCB1 SLC19A1	3.30e-03	84	104	3	C0041755
Disease	blood phosphate measurement	CASR ABCC6 TMEM131 PARP9	3.40e-03	174	104	4	EFO_0010972

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSKIISSGLRIGFLT	AADAT	261	Q8N5Z0
RASKVLGIVFFLFLL	HTR2B	321	P41595
VLQTLTLFKGFFELF	DNPEP	461	Q9ULA0
FTLVISLGIFVFFRS	CALCR	161	P30988
ISFELLGLSTFDFLK	CLK2	241	P49760
LTAFVLGVFIKFRNT	CASR	626	P41180
LFSFFRDVGLKILSN	A2ML1	671	A8K2U0
IKFLTAFRDLLFTTL	ADTRP	76	Q96IZ2
AKLSLLGLAAFFSLS	ADTRP	186	Q96IZ2
RLTLLAIFISTFLFS	DPY19L3	241	Q6ZPD9
LTSILYLGEKTFSFR	BVES-AS1	61	Q5T3Y7
LLATISADRFLLVFK	C5AR1	126	P21730
LFIFLGKSLFSLLEA	SDR16C5	11	Q8N3Y7
FSKLLFKRGSLITSL	TP53I3	251	Q53FA7
SGRITSLSLLFQKVF	PARP9	16	Q8IXQ6
FFILLSVLKIRSFSG	OR5I1	221	Q13606
SLLFLALGIISFITF	ABCB1	756	P08183
RKSVLEGIIAFFSAL	FANCI	226	Q9NVI1
KLFRSEALFLLLSNF	OGFOD1	346	Q8N543
RAPLLKTFSFLGFEI	OAZ2	146	O95190
LFFLKNIGFDSTVLL	LINS1	496	Q8NG48
RGTLRFIKLFTELSF	GLP1R	376	P43220
LKLGSAFTFRVTVLQ	KIF1B	1111	O60333
KRIAFLFDSTLTAFL	FAM91A1	376	Q658Y4
LRRGTCAFSILFKLF	GAPVD1	171	Q14C86
TKLLRLIDLDFSFTF	DYNC2I1	491	Q8WVS4
LSFLGTFILKVAESL	DPAGT1	326	Q9H3H5
LTLKGFLFLHTLFIQ	RHOT1	246	Q8IXI2
KIGLSALTRGFVFFF	OR51D1	156	Q8NGF3
IKIGLTIIGRSFFFI	OR51V1	151	Q9H2C8
TFILLFFSLSGLSII	PTGER4	96	P35408
ILFLFLSELTGFITT	ERGIC1	36	Q969X5
TLRSAKLFFDLFLSS	GCGR	376	P47871
SLIFSALFILFGTVI	DNAJC16	541	Q9Y2G8
FKVSVLVLFALAFLT	NSG1	81	P42857
TFSFGVIFLFTLLKP	MS4A5	61	Q9H3V2
SLFFRSLKDRGFELT	DDOST	61	P39656
LIAFFILTTIKGSAF	PIGU	166	Q9H490
VAATERTLLGFFLAK	POLA1	611	P09884
FKTKAFTTILILFVG	GPR45	261	Q9Y5Y3
LFRKAFDQRLTFTIG	DTX3	281	Q8N9I9
RTSFALLFLGLFGVL	DNASE2B	11	Q8WZ79
LTLSGKIRVTVTFFL	GNRHR	31	P30968
KIRVTVTFFLFLLSA	GNRHR	36	P30968
SLSRVLKVKGFFLIT	EEF1AKMT2	176	Q5JPI9
RFLNSLGTIFSFISK	CPTP	41	Q5TA50
QKFLFLLFLSGLVTL	MAN1C1	21	Q9NR34
FIFIPGVFSLKSSTL	EQTN	6	Q9NQ60
FSRVSLRLVGLKKSF	FASN	1381	P49327
SALSIKFTGRVEFIF	RNF103	251	O00237
FKFLLTFLVALAVGT	SLC39A10	436	Q9ULF5
LLISLGIFFYFKSLS	CALCRL	156	Q16602
VLFTGREFFVGLSKR	DDAH1	131	O94760
LEGRLVTKFSSVFLG	PRAMEF13	251	Q5VWM6
SSLFLFSVLLFVAVR	PCDHB6	696	Q9Y5E3
TAFFVLLFSLLSLLG	TAS2R41	6	P59536
FILIFSNLKLRSVFS	TAS2R41	281	P59536
IIASFLFGILSSKLI	SLC9C1	216	Q4G0N8
LREFFTKLGITQLRF	FARSA	391	Q9Y285
IFSSVLLGFARLIKR	SLC16A12	451	Q6ZSM3
SDVFRFTVPKLLSLF	ABCC6	321	O95255
GKFLVVFLLLSSVES	SAMD9L	541	Q8IVG5
FILNLFSFLLRIKTS	TAF1B	541	Q53T94
LSVIAVRKLFTAAGF	SLC17A1	331	Q14916
VVFAFLLSLVTRFTK	SLC9A3	266	P48764
FGFSFLLLTVALLAS	SLC38A6	76	Q8IZM9
LLSLTFVLFLSLAFG	SLAMF1	6	Q13291
SVFTTGFKRLVFLPL	STS	176	P08842
FCKGLTRTLLTFFDL	SMIM10L2A	36	P0DMW4
FCKGLTRTLLTFFDL	SMIM10L2B	36	P0DMW5
RKFTISLTAFLFILP	SLC38A7	176	Q9NVC3
FAFLLALTTRFTKRV	SLC9A5	261	Q14940
LVLILSSVFLFRLFK	CD84	236	Q9UIB8
IFKQAFSLLRFRTSG	MRPL48	16	Q96GC5
FSRGLVKVLFATETF	SKIV2L	651	Q15477
VFKSFLSLLFQGLSV	SPAG4	131	Q9NPE6
RKFFTILASVILFAN	SLC35B1	276	P78383
FIGLRLKSVSFEDSL	SV2A	516	Q7L0J3
SSLLLGDIILSFAKF	PIGW	386	Q7Z7B1
TRKQFGLLSLFFAVL	STEAP1B	141	Q6NZ63
KSFLTGLVVFLLTVF	ABCA8	326	O94911
RILFSSLILISKLFY	CSE1L	206	P55060
GRSKSSLKTLFILFR	ZCCHC3	246	Q9NUD5
GFKFSRASYLLSLLR	PYROXD2	81	Q8N2H3
ISFFLLLFSLVRHTK	TAS2R9	196	Q9NYW1
LARSLKTYGVSFFLV	TLN1	301	Q9Y490
AAVTGLFTSFSKILL	TMTC2	96	Q8N394
LFVSFILRALSNFIK	SCTR	181	P47872
AFLTFSVVLALFLKR	SLC19A1	191	P41440
LKFITTSGSEFVFIL	TMEM131	1081	Q92545
FLLFFLTLRFSVVKR	TNFRSF9	201	Q07011
RKTGTLFLTSYRVIF	WBP2NL	46	Q6ICG8
YIGSFLARAKFISLI	RRN3P1	31	Q2M238
LFGTTVTFKFILANR	ATP6AP1	316	Q15904
TRFKTAFQLLDFILA	SYNGR4	96	O95473
SLLLDAGFLFLLRFS	RPAP1	436	Q9BWH6
LLFCRVTLGKSFLQF	TNKS2	1096	Q9H2K2
IGALRENTFLLKFFS	TSPAN5	81	P62079
LDFISVLTKYFRGSL	PLEKHG7	371	Q6ZR37
LLSAFLFSVGSLFVK	SLC35G1	76	Q2M3R5
FGSSVLSYFLFLKTL	TMC6	241	Q7Z403
LTSFAKGRLLKLRAF	ZMYND10	281	O75800
SIVLVIGKFVRGFFS	PIEZO1	2446	Q92508
IGTTKLRLVEFSAFL	TEAD1	211	P28347
LKLFKLVFGSVSLFA	TRRAP	711	Q9Y4A5
ITLFTGVLFFFTNIK	TRPV4	516	Q9HBA0
LFFTVRSSLFELAKK	SLC38A1	371	Q9H2H9
TVSRLIFTFFLFLGV	SERINC2	36	Q96SA4
ILAKLLFSSSFLIFL	TMEM145	241	Q8NBT3
KVSLFRSILLFLTRF	TMEM39B	151	Q9GZU3
RVSSKVFFTLFALLG	TM7SF3	291	Q9NS93
FSGFKEIFLVSILLL	NALCN	1011	Q8IZF0
TIRFGQFLSTSLLKE	ART4	201	Q93070