| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | transmembrane transporter activity | CACNA1A CHRNA6 ATP13A4 SCN11A ABCA1 KCNH7 SLC4A7 SLC4A8 SLC39A9 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 SLC4A3 SLC7A14 AQP9 CHRNA2 CHRNA4 RHAG CHRNB3 SLC4A2 SLC5A3 GJA4 ORAI1 GJA5 SLC26A8 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 ATP11B SLCO4C1 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A SLC37A2 ATP13A3 TMCO3 PLP2 SLC23A1 ANO3 KCNT1 MFSD5 SLC6A14 ATP6V0A2 | 1.53e-31 | 1180 | 139 | 55 | GO:0022857 |
| GeneOntologyMolecularFunction | monoatomic ion transmembrane transporter activity | CACNA1A CHRNA6 ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 SLC39A9 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 SLC4A3 CHRNA2 CHRNA4 CHRNB3 SLC4A2 SLC5A3 ORAI1 SLC26A8 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 ATP11B SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A ATP13A3 TMCO3 PLP2 SLC23A1 ANO3 KCNT1 SLC6A14 ATP6V0A2 | 4.60e-30 | 793 | 139 | 46 | GO:0015075 |
| GeneOntologyMolecularFunction | transporter activity | CACNA1A CHRNA6 ATP13A4 SCN11A ABCA1 KCNH7 SLC4A7 SLC4A8 SLC39A9 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 SLC4A3 SLC7A14 AQP9 CHRNA2 CHRNA4 RHAG CHRNB3 SLC4A2 SLC5A3 GJA4 ORAI1 GJA5 SLC26A8 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 ATP11B SLCO4C1 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A SLC37A2 ATP13A3 TMCO3 PLP2 SLC23A1 ANO3 KCNT1 MFSD5 SLC6A14 ATP6V0A2 | 1.37e-29 | 1289 | 139 | 55 | GO:0005215 |
| GeneOntologyMolecularFunction | inorganic molecular entity transmembrane transporter activity | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 SLC39A9 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 SLC4A3 AQP9 RHAG SLC4A2 SLC5A3 ORAI1 SLC26A8 SLC9A4 CLCN3 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A SLC37A2 TMCO3 SLC23A1 ANO3 KCNT1 MFSD5 SLC6A14 ATP6V0A2 | 1.79e-25 | 758 | 139 | 41 | GO:0015318 |
| GeneOntologyMolecularFunction | monoatomic cation transmembrane transporter activity | CACNA1A CHRNA6 ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 SLC39A9 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 CHRNA2 CHRNA4 CHRNB3 SLC5A3 ORAI1 SLC9A4 PIEZO2 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A ATP13A3 TMCO3 SLC23A1 KCNT1 SLC6A14 ATP6V0A2 | 2.00e-24 | 664 | 139 | 38 | GO:0008324 |
| GeneOntologyMolecularFunction | channel activity | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 AQP9 CHRNA2 CHRNA4 RHAG CHRNB3 GJA4 ORAI1 GJA5 SLC26A8 PIEZO2 CLCN3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ANO3 KCNT1 | 1.94e-22 | 525 | 139 | 33 | GO:0015267 |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 AQP9 CHRNA2 CHRNA4 RHAG CHRNB3 GJA4 ORAI1 GJA5 SLC26A8 PIEZO2 CLCN3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ANO3 KCNT1 | 2.05e-22 | 526 | 139 | 33 | GO:0022803 |
| GeneOntologyMolecularFunction | inorganic cation transmembrane transporter activity | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 SLC39A9 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 RHAG SLC5A3 ORAI1 SLC9A4 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A TMCO3 SLC23A1 KCNT1 SLC6A14 ATP6V0A2 | 4.69e-19 | 627 | 139 | 32 | GO:0022890 |
| GeneOntologyMolecularFunction | monoatomic ion channel activity | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 CHRNA2 CHRNA4 CHRNB3 ORAI1 SLC26A8 PIEZO2 CLCN3 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ANO3 KCNT1 | 9.98e-19 | 459 | 139 | 28 | GO:0005216 |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 SLC39A9 GRIK3 PKD1L3 ORAI2 SLC5A3 ORAI1 SLC9A4 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A TMCO3 SLC23A1 KCNT1 SLC6A14 | 1.41e-18 | 465 | 139 | 28 | GO:0046873 |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 TMEM63C GRIK3 OTOP3 PKD1L3 ORAI2 CHRNA2 CHRNA4 CHRNB3 ORAI1 PIEZO2 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A KCNT1 | 1.73e-17 | 343 | 139 | 24 | GO:0005261 |
| GeneOntologyMolecularFunction | aspartic-type endopeptidase activity | ERVK-6 PSEN2 ERVK-7 ERVK-21 ERVK-9 CNTNAP5 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 | 9.11e-16 | 37 | 139 | 11 | GO:0004190 |
| GeneOntologyMolecularFunction | aspartic-type peptidase activity | ERVK-6 PSEN2 ERVK-7 ERVK-21 ERVK-9 CNTNAP5 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 | 1.28e-15 | 38 | 139 | 11 | GO:0070001 |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | OR8H2 CHRNA6 ABCA1 GPR22 OR8B4 OR5AK2 SLC39A9 TMEM116 OR1S2 OR9Q1 MC5R TMEM63C OR2V1 ADGRL1 OR5AK3P VN1R17P GPR63 GRIK3 SUCNR1 PKD1L3 CHRNA2 CHRNA4 ADCYAP1R1 CHRNB3 OR9A1P TAS2R10 TAS2R14 PTPRA ADGRG2 OR6C70 OR52E4 RRH TAS2R45 OR2V2 OR4D5 MUSK IL23R OR9A2 OR10A5 | 1.00e-14 | 1353 | 139 | 39 | GO:0004888 |
| GeneOntologyMolecularFunction | sodium ion transmembrane transporter activity | SCN11A SLC4A7 SLC4A8 GRIK3 SLC5A3 SLC9A4 SLC12A3 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A SLC23A1 SLC6A14 | 6.25e-14 | 171 | 139 | 16 | GO:0015081 |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | OR8H2 GPR22 OR8B4 OR5AK2 SLC39A9 TMEM116 OR1S2 OR9Q1 MC5R OR2V1 ADGRL1 OR5AK3P VN1R17P GPR63 GRIK3 SUCNR1 ADCYAP1R1 OR9A1P TAS2R10 TAS2R14 ADGRG2 OR6C70 OR52E4 RRH TAS2R45 OR2V2 OR4D5 OR9A2 OR10A5 | 2.28e-12 | 884 | 139 | 29 | GO:0004930 |
| GeneOntologyMolecularFunction | gated channel activity | CACNA1A CHRNA6 KCNH7 ANO1 TMEM63C GRIK3 TMC3 CHRNA2 CHRNA4 CHRNB3 PIEZO2 CLCN3 KCNQ5 CATSPER2 SCN1A SCN2A ANO3 KCNT1 | 1.98e-11 | 334 | 139 | 18 | GO:0022836 |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | ATP13A4 ABCA1 SLC4A7 SLC4A8 SLC4A3 SLC4A2 SLC5A3 SLC26A8 SLC9A4 CLCN3 SLC12A3 SLCO4C1 SLC12A4 SLC22A3 SLC37A2 ATP13A3 TMCO3 SLC23A1 SLC6A14 ATP6V0A2 | 1.27e-10 | 477 | 139 | 20 | GO:0022804 |
| GeneOntologyMolecularFunction | inorganic anion transmembrane transporter activity | SLC4A7 SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 SLC22A3 SLC37A2 ANO3 MFSD5 | 2.15e-10 | 171 | 139 | 13 | GO:0015103 |
| GeneOntologyMolecularFunction | secondary active transmembrane transporter activity | SLC4A7 SLC4A8 SLC4A3 SLC4A2 SLC5A3 SLC26A8 SLC9A4 CLCN3 SLC12A3 SLCO4C1 SLC12A4 SLC22A3 SLC37A2 TMCO3 SLC23A1 SLC6A14 | 2.67e-10 | 296 | 139 | 16 | GO:0015291 |
| GeneOntologyMolecularFunction | active monoatomic ion transmembrane transporter activity | ATP13A4 SLC4A7 SLC4A8 SLC4A3 SLC4A2 SLC5A3 SLC26A8 SLC9A4 SLC12A3 SLC12A4 SLC22A3 ATP13A3 TMCO3 SLC23A1 SLC6A14 ATP6V0A2 | 3.41e-10 | 301 | 139 | 16 | GO:0022853 |
| GeneOntologyMolecularFunction | voltage-gated sodium channel activity | 4.01e-10 | 26 | 139 | 7 | GO:0005248 | |
| GeneOntologyMolecularFunction | sodium channel activity | 2.62e-09 | 52 | 139 | 8 | GO:0005272 | |
| GeneOntologyMolecularFunction | monoatomic anion transmembrane transporter activity | SLC4A7 SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 SLC22A3 ANO3 | 8.74e-09 | 151 | 139 | 11 | GO:0008509 |
| GeneOntologyMolecularFunction | chloride transmembrane transporter activity | SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 SLC22A3 ANO3 | 1.73e-08 | 125 | 139 | 10 | GO:0015108 |
| GeneOntologyMolecularFunction | sodium ion binding | 2.89e-08 | 14 | 139 | 5 | GO:0031402 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic cation channel activity | CHRNA6 KCNH7 ANO1 TMEM63C GRIK3 CHRNA2 CHRNA4 CHRNB3 CATSPER2 KCNT1 | 5.13e-08 | 140 | 139 | 10 | GO:0099094 |
| GeneOntologyMolecularFunction | solute:inorganic anion antiporter activity | 7.97e-08 | 32 | 139 | 6 | GO:0005452 | |
| GeneOntologyMolecularFunction | ligand-gated monoatomic ion channel activity | CHRNA6 KCNH7 ANO1 TMEM63C GRIK3 CHRNA2 CHRNA4 CHRNB3 CATSPER2 ANO3 KCNT1 | 1.10e-07 | 193 | 139 | 11 | GO:0015276 |
| GeneOntologyMolecularFunction | ligand-gated channel activity | CHRNA6 KCNH7 ANO1 TMEM63C GRIK3 CHRNA2 CHRNA4 CHRNB3 CATSPER2 ANO3 KCNT1 | 1.36e-07 | 197 | 139 | 11 | GO:0022834 |
| GeneOntologyMolecularFunction | antiporter activity | SLC4A7 SLC4A8 SLC4A3 SLC4A2 SLC26A8 SLC9A4 CLCN3 SLC37A2 TMCO3 | 5.30e-07 | 138 | 139 | 9 | GO:0015297 |
| GeneOntologyMolecularFunction | alkali metal ion binding | 8.89e-07 | 26 | 139 | 5 | GO:0031420 | |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | SLC4A7 SLC4A8 GRIK3 SLC4A3 SLC7A14 SLC4A2 SLC26A8 SLCO4C1 SLC22A3 SLC37A2 SLC23A1 SLC6A14 | 1.01e-06 | 293 | 139 | 12 | GO:0008514 |
| GeneOntologyMolecularFunction | solute:sodium symporter activity | 1.54e-06 | 81 | 139 | 7 | GO:0015370 | |
| GeneOntologyMolecularFunction | solute:monoatomic cation symporter activity | SLC4A7 SLC4A8 SLC5A3 SLC12A3 SLC12A4 SLC22A3 SLC23A1 SLC6A14 | 1.84e-06 | 119 | 139 | 8 | GO:0015294 |
| GeneOntologyMolecularFunction | olfactory receptor activity | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.95e-06 | 431 | 139 | 14 | GO:0004984 |
| GeneOntologyMolecularFunction | bicarbonate transmembrane transporter activity | 2.63e-06 | 32 | 139 | 5 | GO:0015106 | |
| GeneOntologyMolecularFunction | acetylcholine-gated monoatomic cation-selective channel activity | 4.99e-06 | 17 | 139 | 4 | GO:0022848 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 5.28e-06 | 182 | 139 | 9 | GO:0005244 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 5.77e-06 | 184 | 139 | 9 | GO:0022832 | |
| GeneOntologyMolecularFunction | symporter activity | SLC4A7 SLC4A8 SLC5A3 SLC12A3 SLC12A4 SLC22A3 SLC23A1 SLC6A14 | 1.03e-05 | 150 | 139 | 8 | GO:0015293 |
| GeneOntologyMolecularFunction | acetylcholine receptor activity | 1.80e-05 | 23 | 139 | 4 | GO:0015464 | |
| GeneOntologyMolecularFunction | potassium ion transmembrane transporter activity | 2.25e-05 | 167 | 139 | 8 | GO:0015079 | |
| GeneOntologyMolecularFunction | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 4.76e-05 | 57 | 139 | 5 | GO:1904315 | |
| GeneOntologyMolecularFunction | endopeptidase activity | ERVK-6 PSEN2 ERVK-7 ERVK-21 ERVK-9 MEP1B CNTNAP5 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 | 4.84e-05 | 430 | 139 | 12 | GO:0004175 |
| GeneOntologyMolecularFunction | polyamine transmembrane transporter activity | 5.23e-05 | 11 | 139 | 3 | GO:0015203 | |
| GeneOntologyMolecularFunction | RNA-DNA hybrid ribonuclease activity | 5.23e-05 | 11 | 139 | 3 | GO:0004523 | |
| GeneOntologyMolecularFunction | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | 6.11e-05 | 60 | 139 | 5 | GO:0099529 | |
| GeneOntologyMolecularFunction | monoatomic ion-gated channel activity | 6.11e-05 | 31 | 139 | 4 | GO:0022839 | |
| GeneOntologyMolecularFunction | taste receptor activity | 7.87e-05 | 33 | 139 | 4 | GO:0008527 | |
| GeneOntologyMolecularFunction | chloride:bicarbonate antiporter activity | 8.97e-05 | 13 | 139 | 3 | GO:0140900 | |
| GeneOntologyMolecularFunction | bicarbonate:monoatomic anion antiporter activity | 8.97e-05 | 13 | 139 | 3 | GO:0140829 | |
| GeneOntologyMolecularFunction | transmitter-gated channel activity | 8.98e-05 | 65 | 139 | 5 | GO:0022835 | |
| GeneOntologyMolecularFunction | transmitter-gated monoatomic ion channel activity | 8.98e-05 | 65 | 139 | 5 | GO:0022824 | |
| GeneOntologyMolecularFunction | RNA-directed DNA polymerase activity | 1.14e-04 | 14 | 139 | 3 | GO:0003964 | |
| GeneOntologyMolecularFunction | postsynaptic neurotransmitter receptor activity | 1.78e-04 | 75 | 139 | 5 | GO:0098960 | |
| GeneOntologyMolecularFunction | extracellular ligand-gated monoatomic ion channel activity | 2.01e-04 | 77 | 139 | 5 | GO:0005230 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential | 2.09e-04 | 17 | 139 | 3 | GO:0099508 | |
| GeneOntologyMolecularFunction | excitatory extracellular ligand-gated monoatomic ion channel activity | 2.25e-04 | 43 | 139 | 4 | GO:0005231 | |
| GeneOntologyMolecularFunction | RNA stem-loop binding | 4.00e-04 | 21 | 139 | 3 | GO:0035613 | |
| GeneOntologyMolecularFunction | intramembrane lipid transporter activity | 4.36e-04 | 51 | 139 | 4 | GO:0140303 | |
| GeneOntologyMolecularFunction | chloride:monoatomic cation symporter activity | 5.28e-04 | 23 | 139 | 3 | GO:0015377 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 6.66e-04 | 151 | 139 | 6 | GO:0015085 | |
| GeneOntologyMolecularFunction | neurotransmitter receptor activity | 6.74e-04 | 100 | 139 | 5 | GO:0030594 | |
| GeneOntologyMolecularFunction | sodium:bicarbonate symporter activity | 7.09e-04 | 6 | 139 | 2 | GO:0008510 | |
| GeneOntologyMolecularFunction | monoatomic anion:monoatomic cation symporter activity | 7.63e-04 | 26 | 139 | 3 | GO:0015296 | |
| GeneOntologyMolecularFunction | calcium-activated cation channel activity | 8.54e-04 | 27 | 139 | 3 | GO:0005227 | |
| GeneOntologyMolecularFunction | bitter taste receptor activity | 8.54e-04 | 27 | 139 | 3 | GO:0033038 | |
| GeneOntologyMolecularFunction | potassium:chloride symporter activity | 1.68e-03 | 9 | 139 | 2 | GO:0015379 | |
| GeneOntologyMolecularFunction | amine transmembrane transporter activity | 1.68e-03 | 9 | 139 | 2 | GO:0005275 | |
| GeneOntologyMolecularFunction | phosphatidylserine floppase activity | 1.68e-03 | 9 | 139 | 2 | GO:0090556 | |
| GeneOntologyMolecularFunction | phospholipid transporter activity | 1.77e-03 | 74 | 139 | 4 | GO:0005548 | |
| GeneOntologyMolecularFunction | odorant binding | 1.96e-03 | 127 | 139 | 5 | GO:0005549 | |
| GeneOntologyMolecularFunction | peptidase activity | ERVK-6 PSEN2 ERVK-7 ERVK-21 ERVK-9 MEP1B CNTNAP5 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 | 2.09e-03 | 654 | 139 | 12 | GO:0008233 |
| GeneOntologyMolecularFunction | calcium channel activity | 2.10e-03 | 129 | 139 | 5 | GO:0005262 | |
| GeneOntologyMolecularFunction | RNA endonuclease activity, producing 5'-phosphomonoesters | 2.16e-03 | 37 | 139 | 3 | GO:0016891 | |
| GeneOntologyMolecularFunction | DNA polymerase activity | 2.33e-03 | 38 | 139 | 3 | GO:0034061 | |
| GeneOntologyMolecularFunction | nucleobase transmembrane transporter activity | 2.54e-03 | 11 | 139 | 2 | GO:0015205 | |
| GeneOntologyMolecularFunction | voltage-gated chloride channel activity | 2.54e-03 | 11 | 139 | 2 | GO:0005247 | |
| GeneOntologyMolecularFunction | organic cation transmembrane transporter activity | 2.70e-03 | 83 | 139 | 4 | GO:0015101 | |
| GeneOntologyMolecularFunction | store-operated calcium channel activity | 3.03e-03 | 12 | 139 | 2 | GO:0015279 | |
| GeneOntologyMolecularFunction | ammonium channel activity | 3.03e-03 | 12 | 139 | 2 | GO:0008519 | |
| GeneOntologyMolecularFunction | chloride channel activity | 3.07e-03 | 86 | 139 | 4 | GO:0005254 | |
| GeneOntologyMolecularFunction | carbohydrate transmembrane transporter activity | 3.11e-03 | 42 | 139 | 3 | GO:0015144 | |
| GeneOntologyMolecularFunction | metal cation:monoatomic cation antiporter activity | 3.32e-03 | 43 | 139 | 3 | GO:0140828 | |
| GeneOntologyMolecularFunction | polyol transmembrane transporter activity | 3.57e-03 | 13 | 139 | 2 | GO:0015166 | |
| GeneOntologyMolecularFunction | acetylcholine binding | 3.57e-03 | 13 | 139 | 2 | GO:0042166 | |
| GeneOntologyMolecularFunction | monoatomic cation:bicarbonate symporter activity | 3.57e-03 | 13 | 139 | 2 | GO:0140410 | |
| GeneOntologyMolecularFunction | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 4.03e-03 | 46 | 139 | 3 | GO:0016893 | |
| GeneOntologyMolecularFunction | quaternary ammonium group binding | 4.03e-03 | 46 | 139 | 3 | GO:0050997 | |
| GeneOntologyMolecularFunction | potassium:proton antiporter activity | 4.14e-03 | 14 | 139 | 2 | GO:0015386 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic cation channel activity | 4.25e-03 | 152 | 139 | 5 | GO:0022843 | |
| GeneOntologyMolecularFunction | quaternary ammonium group transmembrane transporter activity | 4.76e-03 | 15 | 139 | 2 | GO:0015651 | |
| GeneOntologyMolecularFunction | floppase activity | 5.42e-03 | 16 | 139 | 2 | GO:0140328 | |
| GeneOntologyMolecularFunction | monoatomic anion channel activity | 5.84e-03 | 103 | 139 | 4 | GO:0005253 | |
| GeneOntologyMolecularFunction | carbohydrate:monoatomic cation symporter activity | 6.11e-03 | 17 | 139 | 2 | GO:0005402 | |
| GeneOntologyMolecularFunction | sodium:chloride symporter activity | 6.11e-03 | 17 | 139 | 2 | GO:0015378 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic anion channel activity | 6.11e-03 | 17 | 139 | 2 | GO:0008308 | |
| GeneOntologyMolecularFunction | mechanosensitive monoatomic ion channel activity | 6.84e-03 | 18 | 139 | 2 | GO:0008381 | |
| GeneOntologyMolecularFunction | toxic substance binding | 6.84e-03 | 18 | 139 | 2 | GO:0015643 | |
| GeneOntologyBiologicalProcess | monoatomic ion transport | CACNA1A CHRNA6 ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 ANO1 TMEM63C CBARP GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 SLC4A3 CHRNA2 CHRNA4 ADCYAP1R1 CHRNB3 SLC4A2 SLC5A3 GJA4 ORAI1 GJA5 SLC26A8 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 ATP11B SLCO4C1 SLC12A4 CATSPER2 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A ATP13A3 TMCO3 PLP2 SLC23A1 ANO3 KCNT1 MFSD5 SLC6A14 ATP6V0A2 | 8.90e-27 | 1374 | 140 | 53 | GO:0006811 |
| GeneOntologyBiologicalProcess | monoatomic ion transmembrane transport | CACNA1A CHRNA6 ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 ANO1 TMEM63C CBARP GRIK3 OTOP3 PKD1L3 ORAI2 TMC3 SLC4A3 CHRNA2 CHRNA4 ADCYAP1R1 CHRNB3 SLC4A2 SLC5A3 ORAI1 SLC26A8 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 ATP11B SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ATP13A3 TMCO3 PLP2 SLC23A1 ANO3 KCNT1 SLC6A14 ATP6V0A2 | 4.08e-26 | 1115 | 140 | 48 | GO:0034220 |
| GeneOntologyBiologicalProcess | inorganic ion transmembrane transport | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 ANO1 CBARP OTOP3 PKD1L3 ORAI2 SLC4A3 ADCYAP1R1 RHAG SLC4A2 SLC5A3 ORAI1 SLC26A8 SLC9A4 CLCN3 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SLC37A2 TMCO3 SLC23A1 ANO3 KCNT1 SLC6A14 ATP6V0A2 | 3.03e-19 | 1017 | 140 | 39 | GO:0098660 |
| GeneOntologyBiologicalProcess | monoatomic cation transmembrane transport | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 ANO1 TMEM63C CBARP OTOP3 PKD1L3 ORAI2 ADCYAP1R1 SLC5A3 ORAI1 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ATP13A3 TMCO3 SLC23A1 KCNT1 SLC6A14 ATP6V0A2 | 1.08e-17 | 942 | 140 | 36 | GO:0098655 |
| GeneOntologyBiologicalProcess | monoatomic cation transport | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 ANO1 TMEM63C CBARP OTOP3 PKD1L3 ORAI2 CHRNA4 ADCYAP1R1 SLC5A3 GJA4 ORAI1 GJA5 SLC9A4 PIEZO2 CLCN3 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ATP13A3 TMCO3 SLC23A1 KCNT1 SLC6A14 ATP6V0A2 | 2.51e-17 | 1157 | 140 | 39 | GO:0006812 |
| GeneOntologyBiologicalProcess | inorganic cation transmembrane transport | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 CBARP OTOP3 PKD1L3 ORAI2 ADCYAP1R1 RHAG SLC5A3 ORAI1 SLC9A4 CLCN3 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A TMCO3 SLC23A1 KCNT1 SLC6A14 ATP6V0A2 | 2.15e-15 | 922 | 140 | 33 | GO:0098662 |
| GeneOntologyBiologicalProcess | metal ion transport | CACNA1A ATP13A4 SCN11A KCNH7 SLC4A7 SLC4A8 PSEN2 SLC39A9 CBARP PKD1L3 ORAI2 CHRNA4 ADCYAP1R1 SLC5A3 GJA4 ORAI1 GJA5 SLC9A4 SLC12A3 KCNQ5 SLC12A4 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A TMCO3 SLC23A1 KCNT1 SLC6A14 | 1.35e-13 | 1000 | 140 | 32 | GO:0030001 |
| GeneOntologyBiologicalProcess | membrane depolarization | CACNA1A CHRNA6 SCN11A CHRNA2 CHRNA4 CHRNB3 GJA5 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 1.94e-12 | 121 | 140 | 13 | GO:0051899 |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | OR8H2 SCN11A OR8B4 OR5AK2 OR1S2 OR9Q1 ANO1 OR2V1 OR5AK3P PKD1L3 OR9A1P TAS2R10 PIEZO2 TAS2R14 OR6C70 SCN1A SCN9A OR52E4 TAS2R45 OR2V2 OR4D5 OR9A2 OR10A5 | 9.02e-12 | 582 | 140 | 23 | GO:0050906 |
| GeneOntologyBiologicalProcess | detection of stimulus | OR8H2 SCN11A OR8B4 OR5AK2 OR1S2 OR9Q1 ANO1 OR2V1 OR5AK3P PKD1L3 OR9A1P TAS2R10 PIEZO2 TAS2R14 OR6C70 SCN1A SCN9A OR52E4 RRH TAS2R45 OR2V2 OR4D5 ANO3 OR9A2 OR10A5 | 1.77e-11 | 722 | 140 | 25 | GO:0051606 |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway | OR8H2 SCN11A ABCA1 GPR22 OR8B4 OR5AK2 SLC39A9 TMEM116 OR1S2 OR9Q1 MC5R ANO1 OR2V1 ADGRL1 OR5AK3P VN1R17P GPR63 GRIK3 SUCNR1 ADCYAP1R1 OR9A1P ORAI1 TAS2R10 TAS2R14 ADGRG2 OR6C70 ENTPD1 OR52E4 RRH TAS2R45 OR2V2 OR4D5 OR9A2 OR10A5 | 4.06e-11 | 1395 | 140 | 34 | GO:0007186 |
| GeneOntologyBiologicalProcess | membrane depolarization during action potential | 9.49e-11 | 36 | 140 | 8 | GO:0086010 | |
| GeneOntologyBiologicalProcess | sensory perception | OR8H2 SCN11A SLC4A7 OR8B4 OR5AK2 OR1S2 OR9Q1 ANO1 OR2V1 OR5AK3P VN1R17P PKD1L3 CHRNA4 OR9A1P TAS2R10 PIEZO2 TAS2R14 OR6C70 SCN1A SCN8A SCN9A OR52E4 RRH TAS2R45 OR2V2 OR4D5 CLRN1 OR9A2 OR10A5 | 1.32e-10 | 1072 | 140 | 29 | GO:0007600 |
| GeneOntologyBiologicalProcess | sodium ion transmembrane transport | SCN11A SLC4A7 SLC4A8 SLC5A3 SLC9A4 SLC12A3 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SLC23A1 SLC6A14 | 1.55e-10 | 208 | 140 | 14 | GO:0035725 |
| GeneOntologyBiologicalProcess | regulation of membrane potential | CACNA1A CHRNA6 SCN11A KCNH7 SLC4A8 ANO1 GRIK3 SLC4A3 CHRNA2 CHRNA4 TSPAN9 CHRNB3 GJA5 PIEZO2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A KCNT1 | 2.01e-10 | 559 | 140 | 21 | GO:0042391 |
| GeneOntologyBiologicalProcess | inorganic anion transport | SLC4A7 SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 SLC37A2 ANO3 MFSD5 SLC6A14 | 3.02e-10 | 180 | 140 | 13 | GO:0015698 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P PKD1L3 OR9A1P TAS2R10 TAS2R14 OR6C70 OR52E4 TAS2R45 OR2V2 OR4D5 OR9A2 OR10A5 | 5.35e-09 | 485 | 140 | 18 | GO:0050907 |
| GeneOntologyBiologicalProcess | sensory perception of chemical stimulus | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P VN1R17P PKD1L3 OR9A1P TAS2R10 TAS2R14 OR6C70 OR52E4 TAS2R45 OR2V2 OR4D5 OR9A2 OR10A5 | 5.71e-09 | 547 | 140 | 19 | GO:0007606 |
| GeneOntologyBiologicalProcess | sodium ion transport | SCN11A SLC4A7 SLC4A8 SLC5A3 SLC9A4 SLC12A3 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SLC23A1 SLC6A14 | 5.86e-09 | 275 | 140 | 14 | GO:0006814 |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential | 7.73e-09 | 87 | 140 | 9 | GO:0086001 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell action potential involved in contraction | 9.14e-09 | 62 | 140 | 8 | GO:0086002 | |
| GeneOntologyBiologicalProcess | neuronal action potential | 1.04e-08 | 63 | 140 | 8 | GO:0019228 | |
| GeneOntologyBiologicalProcess | chloride transport | SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 ANO3 SLC6A14 | 1.72e-08 | 128 | 140 | 10 | GO:0006821 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P PKD1L3 OR9A1P TAS2R10 TAS2R14 OR6C70 OR52E4 TAS2R45 OR2V2 OR4D5 OR9A2 OR10A5 | 1.76e-08 | 524 | 140 | 18 | GO:0009593 |
| GeneOntologyBiologicalProcess | inorganic anion transmembrane transport | SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 SLC37A2 ANO3 | 2.68e-08 | 134 | 140 | 10 | GO:0098661 |
| GeneOntologyBiologicalProcess | monoatomic anion transport | SLC4A7 SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 ANO3 SLC6A14 | 4.99e-08 | 183 | 140 | 11 | GO:0006820 |
| GeneOntologyBiologicalProcess | chloride transmembrane transport | SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 ANO3 | 7.17e-08 | 112 | 140 | 9 | GO:1902476 |
| GeneOntologyBiologicalProcess | transmission of nerve impulse | 7.17e-08 | 112 | 140 | 9 | GO:0019226 | |
| GeneOntologyBiologicalProcess | monoatomic anion transmembrane transport | SLC4A7 SLC4A8 ANO1 SLC4A3 SLC4A2 SLC26A8 CLCN3 SLC12A3 SLC12A4 ANO3 | 9.44e-08 | 153 | 140 | 10 | GO:0098656 |
| GeneOntologyBiologicalProcess | bicarbonate transport | 2.03e-07 | 38 | 140 | 6 | GO:0015701 | |
| GeneOntologyBiologicalProcess | cardiac muscle cell contraction | 2.31e-07 | 93 | 140 | 8 | GO:0086003 | |
| GeneOntologyBiologicalProcess | regulation of intracellular pH | 2.51e-07 | 94 | 140 | 8 | GO:0051453 | |
| GeneOntologyBiologicalProcess | regulation of cellular pH | 4.38e-07 | 101 | 140 | 8 | GO:0030641 | |
| GeneOntologyBiologicalProcess | synaptic transmission, cholinergic | 5.01e-07 | 44 | 140 | 6 | GO:0007271 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus | 7.71e-07 | 75 | 140 | 7 | GO:0050982 | |
| GeneOntologyBiologicalProcess | action potential | SCN11A SLC4A3 CHRNA4 GJA5 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 1.18e-06 | 201 | 140 | 10 | GO:0001508 |
| GeneOntologyBiologicalProcess | response to pain | 1.23e-06 | 51 | 140 | 6 | GO:0048265 | |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.50e-06 | 432 | 140 | 14 | GO:0050911 |
| GeneOntologyBiologicalProcess | regulation of pH | 1.63e-06 | 120 | 140 | 8 | GO:0006885 | |
| GeneOntologyBiologicalProcess | cardiac muscle contraction | 2.13e-06 | 167 | 140 | 9 | GO:0060048 | |
| GeneOntologyBiologicalProcess | actin-mediated cell contraction | 2.50e-06 | 127 | 140 | 8 | GO:0070252 | |
| GeneOntologyBiologicalProcess | sensory perception of smell | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 3.53e-06 | 465 | 140 | 14 | GO:0007608 |
| GeneOntologyBiologicalProcess | actin filament-based movement | 9.97e-06 | 153 | 140 | 8 | GO:0030048 | |
| GeneOntologyBiologicalProcess | organic anion transport | CACNA1A SLC4A7 SLC4A8 SLC4A3 SLC7A14 AQP9 RHAG SLC4A2 SLC26A8 SLCO4C1 SLC22A3 SLC37A2 SLC23A1 SLC6A14 | 1.13e-05 | 515 | 140 | 14 | GO:0015711 |
| GeneOntologyBiologicalProcess | striated muscle contraction | 1.78e-05 | 217 | 140 | 9 | GO:0006941 | |
| GeneOntologyBiologicalProcess | detection of external stimulus | 2.43e-05 | 173 | 140 | 8 | GO:0009581 | |
| GeneOntologyBiologicalProcess | monoatomic cation homeostasis | CACNA1A ATP13A4 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 SLC4A3 RHAG SLC4A2 SLC9A4 CLCN3 SLC12A3 SLC12A4 ATP13A3 ATP6V0A2 | 2.44e-05 | 705 | 140 | 16 | GO:0055080 |
| GeneOntologyBiologicalProcess | acetylcholine receptor signaling pathway | 2.45e-05 | 51 | 140 | 5 | GO:0095500 | |
| GeneOntologyBiologicalProcess | multicellular organismal response to stress | 2.46e-05 | 126 | 140 | 7 | GO:0033555 | |
| GeneOntologyBiologicalProcess | detection of abiotic stimulus | 2.64e-05 | 175 | 140 | 8 | GO:0009582 | |
| GeneOntologyBiologicalProcess | cellular response to acetylcholine | 2.96e-05 | 53 | 140 | 5 | GO:1905145 | |
| GeneOntologyBiologicalProcess | monoatomic ion homeostasis | CACNA1A ATP13A4 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 SLC4A3 RHAG SLC4A2 SLC9A4 CLCN3 SLC12A3 SLC12A4 ATP13A3 ATP6V0A2 | 2.99e-05 | 717 | 140 | 16 | GO:0050801 |
| GeneOntologyBiologicalProcess | heart contraction | SCN11A PSEN2 SLC4A3 GJA5 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 3.74e-05 | 298 | 140 | 10 | GO:0060047 |
| GeneOntologyBiologicalProcess | response to acetylcholine | 3.88e-05 | 56 | 140 | 5 | GO:1905144 | |
| GeneOntologyBiologicalProcess | amine transport | 4.21e-05 | 137 | 140 | 7 | GO:0015837 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus involved in sensory perception | 4.23e-05 | 57 | 140 | 5 | GO:0050974 | |
| GeneOntologyBiologicalProcess | heart process | SCN11A PSEN2 SLC4A3 GJA5 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 5.08e-05 | 309 | 140 | 10 | GO:0003015 |
| GeneOntologyBiologicalProcess | behavioral response to pain | 6.31e-05 | 32 | 140 | 4 | GO:0048266 | |
| GeneOntologyBiologicalProcess | detection of temperature stimulus | 7.14e-05 | 33 | 140 | 4 | GO:0016048 | |
| GeneOntologyBiologicalProcess | DNA integration | 8.33e-05 | 13 | 140 | 3 | GO:0015074 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic ion homeostasis | CACNA1A ATP13A4 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 SLC4A3 RHAG SLC4A2 SLC9A4 CLCN3 ATP13A3 ATP6V0A2 | 8.81e-05 | 622 | 140 | 14 | GO:0006873 |
| GeneOntologyBiologicalProcess | potassium ion transport | 1.03e-04 | 272 | 140 | 9 | GO:0006813 | |
| GeneOntologyBiologicalProcess | polyamine transmembrane transport | 1.05e-04 | 14 | 140 | 3 | GO:1902047 | |
| GeneOntologyBiologicalProcess | postsynaptic signal transduction | 1.06e-04 | 69 | 140 | 5 | GO:0098926 | |
| GeneOntologyBiologicalProcess | cell junction assembly | CACNA1A SLC39A9 LRFN3 ADGRL1 LRRTM1 SLITRK1 CLDN8 GJA4 GJA5 PTPRA LRFN5 OCLN MUSK | 1.37e-04 | 569 | 140 | 13 | GO:0034329 |
| GeneOntologyBiologicalProcess | circulatory system process | SCN11A SLC4A8 PSEN2 SUCNR1 SLC4A3 SLC5A3 GJA5 SCN1A SLC22A3 SCN2A SCN3A SCN4A SCN8A SCN9A OCLN | 1.41e-04 | 733 | 140 | 15 | GO:0003013 |
| GeneOntologyBiologicalProcess | regulation of presynapse assembly | 1.86e-04 | 42 | 140 | 4 | GO:1905606 | |
| GeneOntologyBiologicalProcess | calcium ion transport | CACNA1A ATP13A4 SCN11A PSEN2 CBARP PKD1L3 ORAI2 CHRNA4 ADCYAP1R1 GJA4 ORAI1 CATSPER2 | 1.87e-04 | 509 | 140 | 12 | GO:0006816 |
| GeneOntologyBiologicalProcess | polyamine transport | 1.94e-04 | 17 | 140 | 3 | GO:0015846 | |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception of pain | 2.04e-04 | 43 | 140 | 4 | GO:0062149 | |
| GeneOntologyBiologicalProcess | sensory perception of mechanical stimulus | 2.26e-04 | 238 | 140 | 8 | GO:0050954 | |
| GeneOntologyBiologicalProcess | regulation of presynapse organization | 2.66e-04 | 46 | 140 | 4 | GO:0099174 | |
| GeneOntologyBiologicalProcess | intracellular monoatomic cation homeostasis | CACNA1A ATP13A4 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 SLC4A3 SLC4A2 SLC9A4 CLCN3 ATP13A3 ATP6V0A2 | 2.74e-04 | 611 | 140 | 13 | GO:0030003 |
| GeneOntologyBiologicalProcess | cell-cell fusion | 2.85e-04 | 85 | 140 | 5 | GO:0140253 | |
| GeneOntologyBiologicalProcess | syncytium formation by plasma membrane fusion | 2.85e-04 | 85 | 140 | 5 | GO:0000768 | |
| GeneOntologyBiologicalProcess | chemical homeostasis | CACNA1A ATP13A4 ABCA1 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 TLCD4 ANO1 SUCNR1 SLC4A3 RHAG SLC4A2 SLC9A4 CLCN3 SLC12A3 SLC12A4 ATP13A3 ATP6V0A2 | 2.98e-04 | 1249 | 140 | 20 | GO:0048878 |
| GeneOntologyBiologicalProcess | calcium ion transmembrane transport | CACNA1A ATP13A4 SCN11A PSEN2 CBARP PKD1L3 ORAI2 ADCYAP1R1 ORAI1 CATSPER2 | 3.52e-04 | 392 | 140 | 10 | GO:0070588 |
| GeneOntologyBiologicalProcess | syncytium formation | 3.52e-04 | 89 | 140 | 5 | GO:0006949 | |
| GeneOntologyBiologicalProcess | cellular homeostasis | CACNA1A ATP13A4 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 ANO1 SLC4A3 RHAG SLC4A2 SLC9A4 CLCN3 SLC12A3 SLC12A4 ATP13A3 ATP6V0A2 | 3.59e-04 | 981 | 140 | 17 | GO:0019725 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of taste | 3.68e-04 | 50 | 140 | 4 | GO:0050912 | |
| GeneOntologyBiologicalProcess | behavioral response to chemical pain | 4.51e-04 | 5 | 140 | 2 | GO:0061366 | |
| GeneOntologyBiologicalProcess | behavioral response to formalin induced pain | 4.51e-04 | 5 | 140 | 2 | GO:0061368 | |
| GeneOntologyBiologicalProcess | organic cation transport | 4.72e-04 | 145 | 140 | 6 | GO:0015695 | |
| GeneOntologyBiologicalProcess | dopamine transport | 6.08e-04 | 57 | 140 | 4 | GO:0015872 | |
| GeneOntologyBiologicalProcess | chloride ion homeostasis | 6.31e-04 | 25 | 140 | 3 | GO:0055064 | |
| GeneOntologyBiologicalProcess | response to nicotine | 6.49e-04 | 58 | 140 | 4 | GO:0035094 | |
| GeneOntologyBiologicalProcess | positive regulation of reactive oxygen species biosynthetic process | 7.10e-04 | 26 | 140 | 3 | GO:1903428 | |
| GeneOntologyBiologicalProcess | detection of mechanical stimulus involved in sensory perception of pain | 7.10e-04 | 26 | 140 | 3 | GO:0050966 | |
| GeneOntologyBiologicalProcess | detection of temperature stimulus involved in sensory perception of pain | 7.10e-04 | 26 | 140 | 3 | GO:0050965 | |
| GeneOntologyBiologicalProcess | presynapse assembly | 7.38e-04 | 60 | 140 | 4 | GO:0099054 | |
| GeneOntologyBiologicalProcess | sensory perception of pain | 7.52e-04 | 105 | 140 | 5 | GO:0019233 | |
| GeneOntologyBiologicalProcess | intracellular chemical homeostasis | CACNA1A ATP13A4 SLC4A7 SLC4A8 PSEN2 SLC39A9 TM9SF4 ANO1 SLC4A3 RHAG SLC4A2 SLC9A4 CLCN3 ATP13A3 ATP6V0A2 | 8.14e-04 | 866 | 140 | 15 | GO:0055082 |
| GeneOntologyBiologicalProcess | response to toxic substance | 8.17e-04 | 289 | 140 | 8 | GO:0009636 | |
| GeneOntologyBiologicalProcess | monoatomic anion homeostasis | 8.85e-04 | 28 | 140 | 3 | GO:0055081 | |
| GeneOntologyBiologicalProcess | potassium ion transmembrane transport | 1.05e-03 | 232 | 140 | 7 | GO:0071805 | |
| GeneOntologyBiologicalProcess | detection of temperature stimulus involved in sensory perception | 1.09e-03 | 30 | 140 | 3 | GO:0050961 | |
| GeneOntologyBiologicalProcess | sensory perception of taste | 1.32e-03 | 70 | 140 | 4 | GO:0050909 | |
| GeneOntologyBiologicalProcess | regulation of postsynaptic membrane potential | 1.45e-03 | 180 | 140 | 6 | GO:0060078 | |
| GeneOntologyBiologicalProcess | response to mechanical stimulus | 1.51e-03 | 247 | 140 | 7 | GO:0009612 | |
| GeneOntologyBiologicalProcess | presynapse organization | 1.54e-03 | 73 | 140 | 4 | GO:0099172 | |
| GeneOntologyCellularComponent | synaptic membrane | CACNA1A CHRNA6 SCN11A SLC4A8 PSEN2 LRFN3 ANO1 ADGRL1 GRIK3 LRRTM1 SLITRK1 CHRNA2 CHRNA4 CHRNB3 LRFN2 PTPRA CLCN3 KCNQ5 LRFN5 SCN1A SCN2A ENTPD1 SCN8A KCNT1 MUSK | 1.45e-13 | 583 | 141 | 25 | GO:0097060 |
| GeneOntologyCellularComponent | monoatomic ion channel complex | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 GRIK3 PKD1L3 CHRNA2 CHRNA4 CHRNB3 SLC5A3 ORAI1 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 1.11e-12 | 378 | 141 | 20 | GO:0034702 |
| GeneOntologyCellularComponent | transporter complex | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 GRIK3 PKD1L3 CHRNA2 CHRNA4 CHRNB3 SLC5A3 ORAI1 KCNQ5 ATP11B CATSPER2 SPAAR SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ATP6V0A2 | 2.55e-12 | 550 | 141 | 23 | GO:1990351 |
| GeneOntologyCellularComponent | transmembrane transporter complex | CACNA1A CHRNA6 SCN11A KCNH7 ANO1 GRIK3 PKD1L3 CHRNA2 CHRNA4 CHRNB3 SLC5A3 ORAI1 KCNQ5 CATSPER2 SPAAR SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A ATP6V0A2 | 7.14e-12 | 523 | 141 | 22 | GO:1902495 |
| GeneOntologyCellularComponent | voltage-gated sodium channel complex | 1.00e-11 | 17 | 141 | 7 | GO:0001518 | |
| GeneOntologyCellularComponent | sodium channel complex | 1.34e-11 | 29 | 141 | 8 | GO:0034706 | |
| GeneOntologyCellularComponent | cation channel complex | CACNA1A SCN11A GRIK3 PKD1L3 SLC5A3 ORAI1 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 7.14e-10 | 235 | 141 | 14 | GO:0034703 |
| GeneOntologyCellularComponent | presynaptic membrane | CACNA1A CHRNA6 SCN11A SLC4A8 PSEN2 LRFN3 ANO1 ADGRL1 GRIK3 CHRNA4 KCNQ5 SCN1A SCN2A SCN8A | 5.97e-09 | 277 | 141 | 14 | GO:0042734 |
| GeneOntologyCellularComponent | basal part of cell | ABCA1 SLC4A7 SLC4A8 GKN2 AQP9 CLDN8 SLC4A2 SLC5A3 ORAI1 SLC9A4 SLCO4C1 SLC22A3 ENTPD1 CLRN1 SLC23A1 | 4.25e-08 | 378 | 141 | 15 | GO:0045178 |
| GeneOntologyCellularComponent | postsynaptic membrane | CACNA1A CHRNA6 LRFN3 GRIK3 LRRTM1 SLITRK1 CHRNA2 CHRNA4 CHRNB3 LRFN2 CLCN3 LRFN5 SCN8A KCNT1 MUSK | 1.04e-07 | 405 | 141 | 15 | GO:0045211 |
| GeneOntologyCellularComponent | membrane protein complex | CACNA1A CHRNA6 SCN11A KCNH7 PSEN2 MARCHF6 ANO1 GRIK3 PKD1L3 CHRNA2 CHRNA4 RHAG CHRNB3 SLC5A3 MEP1B GJA4 ORAI1 GJA5 KCNQ5 CATSPER2 SPAAR SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A IL23R ATP6V0A2 | 2.06e-07 | 1498 | 141 | 29 | GO:0098796 |
| GeneOntologyCellularComponent | plasma membrane protein complex | CACNA1A CHRNA6 SCN11A PSEN2 GRIK3 CHRNA2 CHRNA4 CHRNB3 SLC5A3 GJA4 GJA5 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A IL23R | 3.27e-07 | 785 | 141 | 20 | GO:0098797 |
| GeneOntologyCellularComponent | presynapse | CACNA1A CHRNA6 SCN11A SLC4A8 PSEN2 LRFN3 ANO1 ADGRL1 CBARP GRIK3 CHRNA4 CHRNB3 LRFN2 SH3GLB1 CLCN3 KCNQ5 SCN1A SLC22A3 SCN2A ENTPD1 SCN8A | 5.26e-07 | 886 | 141 | 21 | GO:0098793 |
| GeneOntologyCellularComponent | basal plasma membrane | ABCA1 SLC4A7 SLC4A8 AQP9 CLDN8 SLC4A2 SLC5A3 ORAI1 SLC9A4 SLCO4C1 SLC22A3 ENTPD1 SLC23A1 | 8.51e-07 | 354 | 141 | 13 | GO:0009925 |
| GeneOntologyCellularComponent | basolateral plasma membrane | ABCA1 SLC4A7 SLC4A8 AQP9 CLDN8 SLC4A2 SLC5A3 ORAI1 SLC9A4 SLCO4C1 SLC22A3 ENTPD1 | 1.84e-06 | 320 | 141 | 12 | GO:0016323 |
| GeneOntologyCellularComponent | apical plasma membrane | SLC4A7 SLC4A8 ANO1 SLC4A2 SLC5A3 PROM1 SLC9A4 CLCN3 SLC12A3 ADGRG2 SLC22A3 OCLN SLC23A1 SLC6A14 | 5.59e-06 | 487 | 141 | 14 | GO:0016324 |
| GeneOntologyCellularComponent | acetylcholine-gated channel complex | 5.64e-06 | 18 | 141 | 4 | GO:0005892 | |
| GeneOntologyCellularComponent | postsynaptic specialization membrane | 9.20e-06 | 201 | 141 | 9 | GO:0099634 | |
| GeneOntologyCellularComponent | apical part of cell | SLC4A7 SLC4A8 ANO1 IFITM1 SLC4A2 SLC5A3 PROM1 SLC9A4 CLCN3 SLC12A3 ADGRG2 SLC22A3 OCLN SLC23A1 SLC6A14 | 1.16e-05 | 592 | 141 | 15 | GO:0045177 |
| GeneOntologyCellularComponent | axon | SCN11A SLC4A8 LRFN3 ADGRL1 CBARP GRIK3 LRRTM1 ORAI2 ORAI1 CLCN3 KCNQ5 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A PCDH9 | 3.19e-05 | 891 | 141 | 18 | GO:0030424 |
| GeneOntologyCellularComponent | nuclear inner membrane | 4.86e-05 | 59 | 141 | 5 | GO:0005637 | |
| GeneOntologyCellularComponent | cell surface | ABCA1 LRFN3 ANO1 IFITM1 LRRTM1 SUCNR1 PKD1L3 SLC4A3 CHRNA4 ADCYAP1R1 PROM1 LRFN2 CLCN3 ADGRG2 LRFN5 ENTPD1 OCLN HILPDA MUSK IL23R | 5.72e-05 | 1111 | 141 | 20 | GO:0009986 |
| GeneOntologyCellularComponent | postsynaptic density membrane | 9.61e-05 | 157 | 141 | 7 | GO:0098839 | |
| GeneOntologyCellularComponent | distal axon | SCN11A SLC4A8 ADGRL1 CBARP GRIK3 LRRTM1 ORAI2 ORAI1 CLCN3 KCNQ5 PCDH9 | 1.82e-04 | 435 | 141 | 11 | GO:0150034 |
| GeneOntologyCellularComponent | node of Ranvier | 3.15e-04 | 20 | 141 | 3 | GO:0033268 | |
| GeneOntologyCellularComponent | dopaminergic synapse | 4.21e-04 | 22 | 141 | 3 | GO:0098691 | |
| GeneOntologyCellularComponent | vacuolar membrane | HGSNAT IFITM1 SLC7A14 SH3GLB1 CLCN3 ATP11B SLCO4C1 SLC12A4 SPAAR OCLN ATP6V0A2 | 6.63e-04 | 507 | 141 | 11 | GO:0005774 |
| GeneOntologyCellularComponent | axon initial segment | 9.65e-04 | 29 | 141 | 3 | GO:0043194 | |
| GeneOntologyCellularComponent | lysosomal membrane | HGSNAT IFITM1 SLC7A14 CLCN3 ATP11B SLCO4C1 SLC12A4 SPAAR OCLN ATP6V0A2 | 1.19e-03 | 462 | 141 | 10 | GO:0005765 |
| GeneOntologyCellularComponent | lytic vacuole membrane | HGSNAT IFITM1 SLC7A14 CLCN3 ATP11B SLCO4C1 SLC12A4 SPAAR OCLN ATP6V0A2 | 1.19e-03 | 462 | 141 | 10 | GO:0098852 |
| GeneOntologyCellularComponent | glutamatergic synapse | CACNA1A SCN11A SLC4A8 PSEN2 LRFN3 ANO1 ADGRL1 GRIK3 LRRTM1 SLITRK1 CLCN3 LRFN5 SCN2A SCN8A | 1.27e-03 | 817 | 141 | 14 | GO:0098978 |
| GeneOntologyCellularComponent | growth cone | 1.39e-03 | 245 | 141 | 7 | GO:0030426 | |
| GeneOntologyCellularComponent | site of polarized growth | 1.67e-03 | 253 | 141 | 7 | GO:0030427 | |
| GeneOntologyCellularComponent | receptor complex | CHRNA6 GPR63 GRIK3 PKD1L3 CHRNA2 CHRNA4 ADCYAP1R1 CHRNB3 PTPRA MUSK IL23R | 1.97e-03 | 581 | 141 | 11 | GO:0043235 |
| GeneOntologyCellularComponent | postsynapse | CACNA1A CHRNA6 LRFN3 GRIK3 LRRTM1 SLITRK1 CHRNA2 CHRNA4 CHRNB3 LRFN2 CLCN3 LRFN5 SCN8A KCNT1 MUSK | 3.69e-03 | 1018 | 141 | 15 | GO:0098794 |
| GeneOntologyCellularComponent | cell-cell contact zone | 3.78e-03 | 94 | 141 | 4 | GO:0044291 | |
| GeneOntologyCellularComponent | recycling endosome membrane | 7.02e-03 | 112 | 141 | 4 | GO:0055038 | |
| GeneOntologyCellularComponent | postsynaptic specialization | 7.18e-03 | 503 | 141 | 9 | GO:0099572 | |
| HumanPheno | Complex febrile seizure | 1.74e-07 | 16 | 45 | 5 | HP:0011172 | |
| HumanPheno | Focal hemiclonic seizure | 2.00e-06 | 25 | 45 | 5 | HP:0006813 | |
| HumanPheno | Blurred vision | 2.42e-06 | 46 | 45 | 6 | HP:0000622 | |
| HumanPheno | Focal automatism seizure | 2.50e-06 | 12 | 45 | 4 | HP:0032898 | |
| HumanPheno | Focal-onset seizure | CACNA1A MARCHF6 CHRNA2 CHRNA4 CLCN3 SLC12A3 KCNQ5 SCN1A SCN2A SCN3A SCN8A SCN9A KCNT1 | 5.21e-06 | 346 | 45 | 13 | HP:0007359 |
| HumanPheno | Facial tics | 6.76e-06 | 15 | 45 | 4 | HP:0011468 | |
| HumanPheno | EEG with focal epileptiform discharges | 6.88e-06 | 118 | 45 | 8 | HP:0011185 | |
| HumanPheno | Generalized clonic seizure | 9.85e-06 | 34 | 45 | 5 | HP:0011169 | |
| HumanPheno | Focal impaired awareness seizure | 1.12e-05 | 126 | 45 | 8 | HP:0002384 | |
| HumanPheno | Focal motor seizure | 1.49e-05 | 131 | 45 | 8 | HP:0011153 | |
| HumanPheno | Generalized tonic seizure | 1.72e-05 | 64 | 45 | 6 | HP:0010818 | |
| HumanPheno | Somnambulism | 2.20e-05 | 7 | 45 | 3 | HP:0025236 | |
| HumanPheno | Focal hyperkinetic seizure | 2.20e-05 | 7 | 45 | 3 | HP:0011174 | |
| HumanPheno | Focal non-motor seizure | 2.24e-05 | 40 | 45 | 5 | HP:0032679 | |
| HumanPheno | Tonic seizure | 2.43e-05 | 140 | 45 | 8 | HP:0032792 | |
| HumanPheno | Focal clonic seizure | 2.86e-05 | 42 | 45 | 5 | HP:0002266 | |
| HumanPheno | Photosensitive myoclonic seizure | 3.50e-05 | 8 | 45 | 3 | HP:0001327 | |
| HumanPheno | Cyanotic episode | 3.50e-05 | 8 | 45 | 3 | HP:0200048 | |
| HumanPheno | Focal tonic seizure | 4.16e-05 | 23 | 45 | 4 | HP:0011167 | |
| HumanPheno | Confusional arousal | 5.22e-05 | 9 | 45 | 3 | HP:0025237 | |
| HumanPheno | Epileptic aura | 5.87e-05 | 25 | 45 | 4 | HP:0033348 | |
| HumanPheno | Clonic seizure | 6.66e-05 | 81 | 45 | 6 | HP:0020221 | |
| HumanPheno | EEG with focal spikes | 6.90e-05 | 26 | 45 | 4 | HP:0011193 | |
| HumanPheno | Epileptic encephalopathy | 6.92e-05 | 119 | 45 | 7 | HP:0200134 | |
| HumanPheno | Simple febrile seizure | 8.04e-05 | 27 | 45 | 4 | HP:0011171 | |
| HumanPheno | Increased theta frequency activity in EEG | 1.01e-04 | 11 | 45 | 3 | HP:0031535 | |
| HumanPheno | Limited neck range of motion | 1.01e-04 | 11 | 45 | 3 | HP:0000466 | |
| HumanPheno | Bilateral tonic-clonic seizure | CACNA1A MARCHF6 CHRNA2 CHRNA4 GJA5 CLCN3 SCN1A SCN2A SCN3A SCN8A SCN9A KCNT1 | 1.06e-04 | 394 | 45 | 12 | HP:0002069 |
| HumanPheno | Status epilepticus with prominent motor symptoms | 1.07e-04 | 29 | 45 | 4 | HP:0032658 | |
| HumanPheno | Pes valgus | 1.17e-04 | 56 | 45 | 5 | HP:0008081 | |
| HumanPheno | Progressive gait ataxia | 1.23e-04 | 30 | 45 | 4 | HP:0007240 | |
| HumanPheno | Progressive ataxia | 1.23e-04 | 30 | 45 | 4 | HP:0001329 | |
| HumanPheno | Epilepsia partialis continua | 1.34e-04 | 12 | 45 | 3 | HP:0012847 | |
| HumanPheno | Photopsia | 1.72e-04 | 96 | 45 | 6 | HP:0030786 | |
| HumanPheno | Generalized cerebral atrophy/hypoplasia | 1.73e-04 | 13 | 45 | 3 | HP:0007058 | |
| HumanPheno | Reduced impulse control | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SLC12A3 SCN1A SCN2A SCN3A ENTPD1 SCN4A SCN8A SCN9A KCNT1 IL23R | 1.97e-04 | 1032 | 45 | 20 | HP:5200045 |
| HumanPheno | Abnormality of temperature sensation | 2.03e-04 | 34 | 45 | 4 | HP:0100772 | |
| HumanPheno | Impaired temperature sensation | 2.03e-04 | 34 | 45 | 4 | HP:0010829 | |
| HumanPheno | Paresthesia | 2.30e-04 | 144 | 45 | 7 | HP:0003401 | |
| HumanPheno | Limitation of neck motion | 2.55e-04 | 36 | 45 | 4 | HP:0005986 | |
| HumanPheno | Abnormal neck physiology | 2.55e-04 | 36 | 45 | 4 | HP:0025669 | |
| HumanPheno | Disturbance of facial expression | 2.55e-04 | 36 | 45 | 4 | HP:0005324 | |
| HumanPheno | Multifocal epileptiform discharges | 2.56e-04 | 66 | 45 | 5 | HP:0010841 | |
| HumanPheno | Restricted or repetitive behaviors or interests | ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 CLCN3 SCN1A SCN2A SCN8A SCN9A KCNT1 | 2.60e-04 | 368 | 45 | 11 | HP:0031432 |
| HumanPheno | Aortopulmonary collateral arteries | 2.72e-04 | 15 | 45 | 3 | HP:0031834 | |
| HumanPheno | Photosensitive tonic-clonic seizure | 2.72e-04 | 15 | 45 | 3 | HP:0007207 | |
| HumanPheno | Dialeptic seizure | 2.76e-04 | 251 | 45 | 9 | HP:0011146 | |
| HumanPheno | Disinhibition | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SCN1A SCN2A SCN3A ENTPD1 SCN8A SCN9A KCNT1 | 2.86e-04 | 807 | 45 | 17 | HP:0000734 |
| HumanPheno | Inappropriate behavior | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SCN1A SCN2A SCN3A ENTPD1 SCN8A SCN9A KCNT1 | 2.86e-04 | 807 | 45 | 17 | HP:0000719 |
| HumanPheno | Abnormal response to social norms | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SCN1A SCN2A SCN3A ENTPD1 SCN8A SCN9A KCNT1 | 2.86e-04 | 807 | 45 | 17 | HP:5200123 |
| HumanPheno | Social disinhibition | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SCN1A SCN2A SCN3A ENTPD1 SCN8A SCN9A KCNT1 | 2.86e-04 | 807 | 45 | 17 | HP:5200029 |
| HumanPheno | Perseverative thought | ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 CLCN3 SCN1A SCN2A SCN8A SCN9A KCNT1 | 3.22e-04 | 377 | 45 | 11 | HP:0030223 |
| HumanPheno | Dysgenesis of the hippocampus | 3.33e-04 | 16 | 45 | 3 | HP:0025101 | |
| HumanPheno | Status epilepticus | 3.82e-04 | 207 | 45 | 8 | HP:0002133 | |
| HumanPheno | Disordered formal thought process | ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 CLCN3 SCN1A SCN2A SCN8A SCN9A KCNT1 | 3.95e-04 | 386 | 45 | 11 | HP:0025769 |
| HumanPheno | Focal motor status epilepticus | 4.02e-04 | 17 | 45 | 3 | HP:0032663 | |
| HumanPheno | Abnormal hypnopompia | 4.02e-04 | 17 | 45 | 3 | HP:5200297 | |
| HumanPheno | Atypical absence status epilepticus | 4.02e-04 | 17 | 45 | 3 | HP:0011151 | |
| HumanPheno | Focal emotional seizure with laughing | 4.02e-04 | 17 | 45 | 3 | HP:0010821 | |
| HumanPheno | Abnormal vestibular function | 4.49e-04 | 212 | 45 | 8 | HP:0001751 | |
| HumanPheno | Alien limb phenomenon | 4.53e-04 | 4 | 45 | 2 | HP:0032506 | |
| HumanPheno | Focal manual automatism seizure | 4.53e-04 | 4 | 45 | 2 | HP:0032900 | |
| HumanPheno | Focal pedal automatism seizure | 4.53e-04 | 4 | 45 | 2 | HP:0032901 | |
| HumanPheno | Dissociated sensory loss | 4.53e-04 | 4 | 45 | 2 | HP:0010835 | |
| HumanPheno | Visually-induced seizure | 4.79e-04 | 18 | 45 | 3 | HP:0020216 | |
| HumanPheno | Nocturnal seizures | 4.79e-04 | 18 | 45 | 3 | HP:0031951 | |
| HumanPheno | Generalized non-convulsive status epilepticus without coma | 4.79e-04 | 18 | 45 | 3 | HP:0032860 | |
| HumanPheno | Focal emotional seizure | 4.79e-04 | 18 | 45 | 3 | HP:0025613 | |
| HumanPheno | Personality disorder | 4.79e-04 | 18 | 45 | 3 | HP:0012075 | |
| HumanPheno | Cyanosis | 5.06e-04 | 117 | 45 | 6 | HP:0000961 | |
| HumanPheno | Confusion | 5.27e-04 | 77 | 45 | 5 | HP:0001289 | |
| HumanPheno | Recurrent maladaptive behavior | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SLC12A3 SCN1A SCN2A SCN3A ENTPD1 SCN4A SCN8A SCN9A CLRN1 KCNT1 IL23R SLC6A14 | 5.46e-04 | 1293 | 45 | 22 | HP:5200241 |
| HumanPheno | Disturbance during transitions between sleep and wake states | 5.66e-04 | 19 | 45 | 3 | HP:5200293 | |
| HumanPheno | Abnormal thought pattern | ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 CLCN3 SCN1A SCN2A SCN8A SCN9A KCNT1 | 5.84e-04 | 404 | 45 | 11 | HP:5200269 |
| HumanPheno | Generalized-onset seizure | CACNA1A PSEN2 MARCHF6 CHRNA2 CHRNA4 GJA5 CLCN3 SCN1A SCN2A SCN3A SCN8A SCN9A KCNT1 | 5.89e-04 | 544 | 45 | 13 | HP:0002197 |
| HumanPheno | Non-convulsive status epilepticus without coma | 6.61e-04 | 20 | 45 | 3 | HP:0032671 | |
| HumanPheno | NREM parasomnia | 6.61e-04 | 20 | 45 | 3 | HP:0025235 | |
| HumanPheno | Paroxysmal dystonia | 6.61e-04 | 20 | 45 | 3 | HP:0002268 | |
| HumanPheno | Psychomotor deterioration | 6.61e-04 | 20 | 45 | 3 | HP:0002361 | |
| HumanPheno | Atypical absence seizure | 6.62e-04 | 46 | 45 | 4 | HP:0007270 | |
| HumanPheno | Abnormally increased volition | CACNA1A PSEN2 HGSNAT ADGRL1 SLITRK1 CHRNA2 CHRNA4 GJA5 PIEZO2 CLCN3 SCN1A SCN2A SCN3A ENTPD1 SCN8A SCN9A KCNT1 | 7.02e-04 | 869 | 45 | 17 | HP:5200263 |
| HumanPheno | Neonatal electro-clinical non-motor seizure | 7.50e-04 | 5 | 45 | 2 | HP:0032812 | |
| HumanPheno | Neonatal seizure with electrographic correlate | 7.50e-04 | 5 | 45 | 2 | HP:0032808 | |
| HumanPheno | Neonatal electro-clinical seizure | 7.50e-04 | 5 | 45 | 2 | HP:0032809 | |
| HumanPheno | Neonatal electro-clinical seizure with behavior arrest | 7.50e-04 | 5 | 45 | 2 | HP:0032823 | |
| HumanPheno | Seesaw nystagmus | 7.50e-04 | 5 | 45 | 2 | HP:0012044 | |
| HumanPheno | Focal head nodding automatism seizure | 7.50e-04 | 5 | 45 | 2 | HP:0032906 | |
| HumanPheno | Spontaneous pain sensation | 7.50e-04 | 5 | 45 | 2 | HP:0010833 | |
| HumanPheno | Allodynia | 7.50e-04 | 5 | 45 | 2 | HP:0012533 | |
| HumanPheno | Talipes valgus | 7.67e-04 | 21 | 45 | 3 | HP:0004684 | |
| HumanPheno | Abnormal hippocampus morphology | 7.79e-04 | 48 | 45 | 4 | HP:0025100 | |
| HumanPheno | Abnormal morphology of the limbic system | 8.43e-04 | 49 | 45 | 4 | HP:0007343 | |
| HumanPheno | Reflex seizure | 8.82e-04 | 22 | 45 | 3 | HP:0020207 | |
| HumanPheno | Focal sensory seizure | 8.82e-04 | 22 | 45 | 3 | HP:0011157 | |
| HumanPheno | Neonatal onset | CACNA1A ANO1 RHAG CLCN3 SCN3A SCN4A SCN8A SCN9A ATP13A3 OCLN KCNT1 MUSK | 9.78e-04 | 500 | 45 | 12 | HP:0003623 |
| HumanPheno | Suicidal ideation | 1.01e-03 | 23 | 45 | 3 | HP:0031589 | |
| HumanPheno | Tibial torsion | 1.01e-03 | 23 | 45 | 3 | HP:0100694 | |
| HumanPheno | Bilateral tonic-clonic seizure with focal onset | 1.06e-03 | 52 | 45 | 4 | HP:0007334 | |
| HumanPheno | Normal interictal EEG | 1.12e-03 | 6 | 45 | 2 | HP:0002372 | |
| HumanPheno | Impairment of activities of daily living | 1.15e-03 | 188 | 45 | 7 | HP:0031058 | |
| MousePheno | abnormal synaptic transmission | CACNA1A SCN11A LRFN3 MARCHF6 ADGRL1 CBARP GRIK3 RNF43 CHRNA2 CHRNA4 ADCYAP1R1 SLC9A4 CNTNAP5 LRFN2 PTPRA CLCN3 SCN1A SCN2A ENTPD1 SCN8A SCN9A CLRN1 PCDH9 KCNT1 MUSK | 8.73e-08 | 1070 | 100 | 25 | MP:0003635 |
| MousePheno | abnormal synaptic physiology | CACNA1A SCN11A LRFN3 MARCHF6 ADGRL1 CBARP GRIK3 RNF43 CHRNA2 CHRNA4 ADCYAP1R1 SLC9A4 CNTNAP5 LRFN2 PTPRA CLCN3 SCN1A SCN2A ENTPD1 SCN8A SCN9A CLRN1 PCDH9 KCNT1 MUSK | 9.73e-08 | 1076 | 100 | 25 | MP:0021009 |
| MousePheno | abnormal neurotransmitter secretion | 8.08e-06 | 67 | 100 | 6 | MP:0005445 | |
| MousePheno | abnormal CNS synaptic transmission | CACNA1A SCN11A LRFN3 MARCHF6 CBARP GRIK3 RNF43 CHRNA2 CHRNA4 ADCYAP1R1 SLC9A4 CNTNAP5 LRFN2 PTPRA CLCN3 SCN1A SCN2A SCN9A PCDH9 KCNT1 | 1.80e-05 | 985 | 100 | 20 | MP:0002206 |
| MousePheno | abnormal nervous system electrophysiology | CACNA1A SCN11A CHRNA4 SLC5A3 KCNQ5 SCN1A SCN2A SCN8A SCN9A CLRN1 KCNT1 | 2.27e-05 | 329 | 100 | 11 | MP:0002272 |
| MousePheno | abnormal sensory capabilities/reflexes/nociception | CACNA1A SCN11A ABCA1 SLC4A8 TMEM116 HGSNAT CBARP SLITRK1 CHRNA4 CHRNB3 CCNT2 ORAI1 SLC9A4 LRFN2 PTPRA SCN1A SCN4A SCN8A SCN9A ATP13A3 TMCO3 CLRN1 PCDH9 KCNT1 MUSK | 3.40e-05 | 1486 | 100 | 25 | MP:0002067 |
| MousePheno | abnormal social/conspecific interaction behavior | CACNA1A MC5R ADGRL1 CBARP LRRTM1 LRFN2 PTPRA SCN1A SCN2A OCLN PCDH9 KCNT1 | 4.56e-05 | 421 | 100 | 12 | MP:0002557 |
| MousePheno | abnormal action potential | 4.62e-05 | 133 | 100 | 7 | MP:0005402 | |
| MousePheno | stomach inflammation | 7.60e-05 | 32 | 100 | 4 | MP:0001873 | |
| MousePheno | abnormal muscle electrophysiology | 7.60e-05 | 32 | 100 | 4 | MP:0004145 | |
| MousePheno | abnormal fear/anxiety-related behavior | CACNA1A MARCHF6 HGSNAT CBARP GRIK3 LRRTM1 SLITRK1 CHRNA4 ADCYAP1R1 LRFN2 PTPRA LRFN5 SCN1A SLC22A3 SCN2A SCN8A ATP13A3 KCNT1 | 8.07e-05 | 919 | 100 | 18 | MP:0002065 |
| MousePheno | abnormal channel response | 8.60e-05 | 33 | 100 | 4 | MP:0003484 | |
| MousePheno | abnormal seizure response to pharmacological agent | 8.72e-05 | 147 | 100 | 7 | MP:0000950 | |
| MousePheno | abnormal seizure response to inducing agent | 9.54e-05 | 201 | 100 | 8 | MP:0009357 | |
| MousePheno | abnormal gastric gland morphology | 9.70e-05 | 34 | 100 | 4 | MP:0003892 | |
| MousePheno | clonic seizures | 1.22e-04 | 14 | 100 | 3 | MP:0003996 | |
| MousePheno | abnormal synapse morphology | 2.01e-04 | 224 | 100 | 8 | MP:0009538 | |
| MousePheno | abnormal stomach mucosa morphology | 2.23e-04 | 77 | 100 | 5 | MP:0010792 | |
| MousePheno | abnormal anxiety-related response | HGSNAT CBARP GRIK3 LRRTM1 SLITRK1 CHRNA4 ADCYAP1R1 PTPRA LRFN5 SCN1A SLC22A3 SCN2A SCN8A ATP13A3 KCNT1 | 2.36e-04 | 740 | 100 | 15 | MP:0001362 |
| MousePheno | abnormal stomach wall morphology | 2.66e-04 | 80 | 100 | 5 | MP:0010783 | |
| MousePheno | abnormal vertical activity | CACNA1A KCNH7 CBARP LRRTM1 CHRNA2 CHRNA4 ADCYAP1R1 PIEZO2 PTPRA HILPDA PCDH9 | 2.96e-04 | 439 | 100 | 11 | MP:0020167 |
| MousePheno | abnormal gastric chief cell morphology | 3.17e-04 | 19 | 100 | 3 | MP:0004140 | |
| MousePheno | increased anxiety-related response | HGSNAT CBARP LRRTM1 SLITRK1 CHRNA4 SCN1A SCN8A ATP13A3 KCNT1 | 3.84e-04 | 311 | 100 | 9 | MP:0001363 |
| MousePheno | abnormal spike wave discharge | 6.45e-04 | 24 | 100 | 3 | MP:0008840 | |
| MousePheno | abnormal reflex | CACNA1A ABCA1 SLC4A8 TMEM116 HGSNAT CBARP SLITRK1 CHRNB3 CCNT2 ORAI1 SLC9A4 LRFN2 PTPRA SCN1A SCN4A SCN8A ATP13A3 TMCO3 CLRN1 MUSK | 7.37e-04 | 1294 | 100 | 20 | MP:0001961 |
| MousePheno | abnormal Purkinje cell mitochondrial morphology | 7.46e-04 | 6 | 100 | 2 | MP:0014331 | |
| MousePheno | convulsive seizures | 7.97e-04 | 153 | 100 | 6 | MP:0000947 | |
| MousePheno | abnormal miniature endplate potential | 8.19e-04 | 26 | 100 | 3 | MP:0004835 | |
| MousePheno | abnormal gastric parietal cell morphology | 8.19e-04 | 26 | 100 | 3 | MP:0004139 | |
| Domain | Na_channel_asu | 5.99e-14 | 10 | 125 | 7 | IPR001696 | |
| Domain | Na_trans_assoc | 5.99e-14 | 10 | 125 | 7 | IPR010526 | |
| Domain | Na_trans_assoc | 5.99e-14 | 10 | 125 | 7 | PF06512 | |
| Domain | Na_trans_cytopl | 7.39e-11 | 6 | 125 | 5 | PF11933 | |
| Domain | Na_trans_cytopl | 7.39e-11 | 6 | 125 | 5 | IPR024583 | |
| Domain | Channel_four-helix_dom | 1.38e-10 | 57 | 125 | 9 | IPR027359 | |
| Domain | - | 1.38e-10 | 57 | 125 | 9 | 1.20.120.350 | |
| Domain | Ion_trans_dom | CACNA1A SCN11A KCNH7 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 2.78e-10 | 114 | 125 | 11 | IPR005821 |
| Domain | Ion_trans | CACNA1A SCN11A KCNH7 KCNQ5 CATSPER2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A | 2.78e-10 | 114 | 125 | 11 | PF00520 |
| Domain | ANION_EXCHANGER_2 | 6.59e-08 | 7 | 125 | 4 | PS00220 | |
| Domain | ANION_EXCHANGER_1 | 6.59e-08 | 7 | 125 | 4 | PS00219 | |
| Domain | Band3_cytoplasmic_dom | 2.35e-07 | 9 | 125 | 4 | IPR013769 | |
| Domain | Band_3_cyto | 2.35e-07 | 9 | 125 | 4 | PF07565 | |
| Domain | - | 2.35e-07 | 9 | 125 | 4 | 3.40.1100.10 | |
| Domain | HCO3_cotransp | 3.89e-07 | 10 | 125 | 4 | PF00955 | |
| Domain | HCO3_transpt_C | 3.89e-07 | 10 | 125 | 4 | IPR011531 | |
| Domain | PTrfase/Anion_transptr | 3.89e-07 | 10 | 125 | 4 | IPR016152 | |
| Domain | HCO3_transpt_euk | 3.89e-07 | 10 | 125 | 4 | IPR003020 | |
| Domain | GPCR_Rhodpsn_7TM | OR8H2 GPR22 OR8B4 OR5AK2 OR1S2 OR9Q1 MC5R OR2V1 GPR63 SUCNR1 OR6C70 OR52E4 RRH OR2V2 OR4D5 OR9A2 OR10A5 | 2.38e-06 | 670 | 125 | 17 | IPR017452 |
| Domain | Anion_exchange | 2.90e-06 | 5 | 125 | 3 | IPR001717 | |
| Domain | G_PROTEIN_RECEP_F1_1 | OR8H2 GPR22 OR8B4 OR5AK2 OR1S2 OR9Q1 MC5R OR2V1 GPR63 SUCNR1 OR6C70 OR52E4 RRH OR2V2 OR4D5 OR9A2 OR10A5 | 3.20e-06 | 685 | 125 | 17 | PS00237 |
| Domain | Nicotinic_acetylcholine_rcpt | 3.27e-06 | 16 | 125 | 4 | IPR002394 | |
| Domain | G_PROTEIN_RECEP_F1_2 | OR8H2 GPR22 OR8B4 OR5AK2 OR1S2 OR9Q1 MC5R OR2V1 GPR63 SUCNR1 OR6C70 OR52E4 RRH OR2V2 OR4D5 OR9A2 OR10A5 | 3.60e-06 | 691 | 125 | 17 | PS50262 |
| Domain | GPCR_Rhodpsn | OR8H2 GPR22 OR8B4 OR5AK2 OR1S2 OR9Q1 MC5R OR2V1 GPR63 SUCNR1 OR6C70 OR52E4 RRH OR2V2 OR4D5 OR9A2 OR10A5 | 3.67e-06 | 692 | 125 | 17 | IPR000276 |
| Domain | 7tm_1 | OR8H2 GPR22 OR8B4 OR5AK2 OR1S2 OR9Q1 MC5R GPR63 SUCNR1 OR6C70 OR52E4 RRH OR2V2 OR4D5 OR9A2 OR10A5 | 1.18e-05 | 677 | 125 | 16 | PF00001 |
| Domain | Olfact_rcpt | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.32e-05 | 393 | 125 | 12 | IPR000725 |
| Domain | - | 1.53e-05 | 23 | 125 | 4 | 1.20.120.370 | |
| Domain | Acetylcholine_rcpt_TM | 1.53e-05 | 23 | 125 | 4 | IPR027361 | |
| Domain | IQ | 1.72e-05 | 81 | 125 | 6 | SM00015 | |
| Domain | IQ_motif_EF-hand-BS | 3.13e-05 | 90 | 125 | 6 | IPR000048 | |
| Domain | Marvel | 3.46e-05 | 28 | 125 | 4 | IPR008253 | |
| Domain | MARVEL | 3.46e-05 | 28 | 125 | 4 | PS51225 | |
| Domain | IQ | 3.77e-05 | 93 | 125 | 6 | PS50096 | |
| Domain | IQ | 1.13e-04 | 71 | 125 | 5 | PF00612 | |
| Domain | CRAC_channel | 1.33e-04 | 3 | 125 | 2 | IPR012446 | |
| Domain | Anion_exchange_CS | 1.33e-04 | 3 | 125 | 2 | IPR018241 | |
| Domain | Orai-1 | 1.33e-04 | 3 | 125 | 2 | PF07856 | |
| Domain | Neurotransmitter_ion_chnl_CS | 2.30e-04 | 45 | 125 | 4 | IPR018000 | |
| Domain | Neur_chan_memb | 2.51e-04 | 46 | 125 | 4 | PF02932 | |
| Domain | P5-ATPase | 2.64e-04 | 4 | 125 | 2 | PF12409 | |
| Domain | Neur_chan_LBD | 2.73e-04 | 47 | 125 | 4 | PF02931 | |
| Domain | NEUROTR_ION_CHANNEL | 2.73e-04 | 47 | 125 | 4 | PS00236 | |
| Domain | Neurotrans-gated_channel_TM | 2.73e-04 | 47 | 125 | 4 | IPR006029 | |
| Domain | - | 2.73e-04 | 47 | 125 | 4 | 2.70.170.10 | |
| Domain | Neur_channel | 2.73e-04 | 47 | 125 | 4 | IPR006201 | |
| Domain | Neur_chan_lig-bd | 2.73e-04 | 47 | 125 | 4 | IPR006202 | |
| Domain | AA-permease/SLC12A_dom | 4.11e-04 | 22 | 125 | 3 | IPR004841 | |
| Domain | AA_permease | 4.11e-04 | 22 | 125 | 3 | PF00324 | |
| Domain | P-type_TPase_V | 4.39e-04 | 5 | 125 | 2 | IPR006544 | |
| Domain | LRRNT | 5.12e-04 | 98 | 125 | 5 | IPR000372 | |
| Domain | LRRNT | 5.12e-04 | 98 | 125 | 5 | SM00013 | |
| Domain | TAS2R | 6.80e-04 | 26 | 125 | 3 | PF05296 | |
| Domain | T2R | 6.80e-04 | 26 | 125 | 3 | IPR007960 | |
| Domain | MARVEL | 7.61e-04 | 27 | 125 | 3 | PF01284 | |
| Domain | SLC12A_fam | 9.13e-04 | 7 | 125 | 2 | IPR004842 | |
| Domain | Anoct_dimer | 9.13e-04 | 7 | 125 | 2 | PF16178 | |
| Domain | Anoct_dimer | 9.13e-04 | 7 | 125 | 2 | IPR032394 | |
| Domain | SLC12_C | 1.21e-03 | 8 | 125 | 2 | IPR018491 | |
| Domain | SLC12 | 1.21e-03 | 8 | 125 | 2 | PF03522 | |
| Domain | - | 1.26e-03 | 32 | 125 | 3 | 3.40.1110.10 | |
| Domain | - | 1.26e-03 | 32 | 125 | 3 | 2.70.150.10 | |
| Domain | GPS | 1.50e-03 | 34 | 125 | 3 | SM00303 | |
| Domain | GPCR_2_secretin-like_CS | 1.50e-03 | 34 | 125 | 3 | IPR017983 | |
| Domain | GPS | 1.64e-03 | 35 | 125 | 3 | PF01825 | |
| Domain | ATPase_P-typ_cyto_domN | 1.64e-03 | 35 | 125 | 3 | IPR023299 | |
| Domain | P_typ_ATPase | 1.78e-03 | 36 | 125 | 3 | IPR001757 | |
| Domain | ATPase_P-typ_P_site | 1.78e-03 | 36 | 125 | 3 | IPR018303 | |
| Domain | GPS | 1.78e-03 | 36 | 125 | 3 | PS50221 | |
| Domain | ATPASE_E1_E2 | 1.78e-03 | 36 | 125 | 3 | PS00154 | |
| Domain | GPS | 1.93e-03 | 37 | 125 | 3 | IPR000203 | |
| Domain | ATPase_P-typ_transduc_dom_A | 1.93e-03 | 37 | 125 | 3 | IPR008250 | |
| Domain | E1-E2_ATPase | 1.93e-03 | 37 | 125 | 3 | PF00122 | |
| Domain | Anoctamin | 1.93e-03 | 10 | 125 | 2 | PF04547 | |
| Domain | Anoctamin | 1.93e-03 | 10 | 125 | 2 | IPR007632 | |
| Domain | MFS_dom | 2.08e-03 | 134 | 125 | 5 | IPR020846 | |
| Domain | Cys-rich_flank_reg_C | 3.14e-03 | 90 | 125 | 4 | IPR000483 | |
| Domain | LRRCT | 3.14e-03 | 90 | 125 | 4 | SM00082 | |
| Domain | Na_H_Exchanger | 3.84e-03 | 14 | 125 | 2 | PF00999 | |
| Domain | Cation/H_exchanger | 3.84e-03 | 14 | 125 | 2 | IPR006153 | |
| Domain | MS4A | 3.84e-03 | 14 | 125 | 2 | IPR030417 | |
| Domain | G_PROTEIN_RECEP_F2_2 | 4.56e-03 | 50 | 125 | 3 | PS00650 | |
| Domain | 7tm_2 | 4.56e-03 | 50 | 125 | 3 | PF00002 | |
| Domain | CBS | 5.01e-03 | 16 | 125 | 2 | SM00116 | |
| Domain | zf-RING_2 | 5.09e-03 | 52 | 125 | 3 | PF13639 | |
| Domain | Znf_RING-CH | 5.66e-03 | 17 | 125 | 2 | IPR011016 | |
| Domain | RINGv | 5.66e-03 | 17 | 125 | 2 | SM00744 | |
| Domain | MFS | 6.00e-03 | 108 | 125 | 4 | PS50850 | |
| Domain | Cation_ATPase_N | 6.34e-03 | 18 | 125 | 2 | PF00690 | |
| Pathway | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 7.31e-10 | 31 | 89 | 7 | M877 | |
| Pathway | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 9.31e-10 | 32 | 89 | 7 | M27455 | |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | ATP13A4 ABCA1 SLC4A7 SLC4A8 ANO1 SLC4A3 AQP9 RHAG SLC4A2 SLC5A3 SLC9A4 CLCN3 SLC12A3 ATP11B SLCO4C1 SLC12A4 SLC22A3 ANO3 SLC6A14 ATP6V0A2 | 2.30e-08 | 736 | 89 | 20 | M27287 |
| Pathway | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC4A7 SLC4A8 SLC4A3 RHAG SLC4A2 SLC5A3 SLC9A4 SLC12A3 SLCO4C1 SLC12A4 SLC22A3 SLC6A14 | 3.06e-08 | 238 | 89 | 12 | MM15076 |
| Pathway | REACTOME_TRANSPORT_OF_SMALL_MOLECULES | ATP13A4 ABCA1 SLC4A7 SLC4A8 ANO1 SLC4A3 AQP9 RHAG SLC4A2 SLC5A3 SLC9A4 SLC12A3 ATP11B SLCO4C1 SLC12A4 SLC22A3 ANO3 SLC6A14 ATP6V0A2 | 3.63e-08 | 681 | 89 | 19 | MM14985 |
| Pathway | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC4A7 SLC4A8 SLC4A3 RHAG SLC4A2 SLC5A3 SLC9A4 SLC12A3 SLCO4C1 SLC12A4 SLC22A3 SLC6A14 | 5.04e-08 | 249 | 89 | 12 | M5988 |
| Pathway | REACTOME_CARDIAC_CONDUCTION | 1.25e-07 | 130 | 89 | 9 | M27454 | |
| Pathway | REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 1.83e-07 | 9 | 89 | 4 | M27597 | |
| Pathway | REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 1.83e-07 | 9 | 89 | 4 | MM15313 | |
| Pathway | REACTOME_BICARBONATE_TRANSPORTERS | 3.03e-07 | 10 | 89 | 4 | M27335 | |
| Pathway | REACTOME_BICARBONATE_TRANSPORTERS | 3.03e-07 | 10 | 89 | 4 | MM15073 | |
| Pathway | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 3.86e-07 | 108 | 89 | 8 | M823 | |
| Pathway | REACTOME_SENSORY_PERCEPTION | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 TAS2R10 TAS2R14 OR6C70 SCN2A SCN3A SCN9A OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 3.91e-07 | 636 | 89 | 17 | M41834 |
| Pathway | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 4.14e-07 | 109 | 89 | 8 | MM15074 | |
| Pathway | REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 4.74e-07 | 11 | 89 | 4 | M883 | |
| Pathway | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 7.07e-07 | 12 | 89 | 4 | M48008 | |
| Pathway | REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 7.07e-07 | 12 | 89 | 4 | MM15312 | |
| Pathway | REACTOME_NEURONAL_SYSTEM | CACNA1A CHRNA6 KCNH7 LRFN3 GRIK3 LRRTM1 SLITRK1 CHRNA2 CHRNA4 CHRNB3 LRFN2 KCNQ5 | 1.23e-06 | 335 | 89 | 12 | MM14503 |
| Pathway | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | 1.42e-06 | 14 | 89 | 4 | M757 | |
| Pathway | REACTOME_NEURONAL_SYSTEM | CACNA1A CHRNA6 KCNH7 LRFN3 GRIK3 LRRTM1 SLITRK1 CHRNA2 CHRNA4 CHRNB3 PRKAG3 LRFN2 KCNQ5 | 1.71e-06 | 411 | 89 | 13 | M735 |
| Pathway | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | 1.92e-06 | 15 | 89 | 4 | MM14704 | |
| Pathway | REACTOME_MUSCLE_CONTRACTION | 5.24e-06 | 203 | 89 | 9 | M5485 | |
| Pathway | REACTOME_L1CAM_INTERACTIONS | 1.11e-05 | 121 | 89 | 7 | M872 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 1.11e-05 | 47 | 89 | 5 | M42524 | |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.16e-05 | 417 | 89 | 12 | M4072 |
| Pathway | WP_DRAVET_SYNDROME | 2.71e-05 | 28 | 89 | 4 | M45519 | |
| Pathway | KEGG_OLFACTORY_TRANSDUCTION | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 3.25e-05 | 389 | 89 | 11 | M14091 |
| Pathway | WP_GPCRS_NONODORANT | 2.73e-04 | 266 | 89 | 8 | MM15843 | |
| Pathway | KEGG_TASTE_TRANSDUCTION | 3.19e-04 | 52 | 89 | 4 | M5785 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CA2_ENTRY_STORE_OPERATED_CA2_CHANNEL | 3.89e-04 | 5 | 89 | 2 | M49017 | |
| Pathway | WP_GPCRS_CLASS_B_SECRETINLIKE | 4.47e-04 | 24 | 89 | 3 | M39643 | |
| Pathway | WP_GPCRS_CLASS_B_SECRETINLIKE | 4.47e-04 | 24 | 89 | 3 | MM15992 | |
| Pathway | WP_GPCRS_ODORANT | 4.71e-04 | 157 | 89 | 6 | MM15872 | |
| Pathway | WP_1Q211_COPY_NUMBER_VARIATION_SYNDROME | 7.89e-04 | 29 | 89 | 3 | M39890 | |
| Pathway | REACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS | 8.11e-04 | 7 | 89 | 2 | M27339 | |
| Pathway | REACTOME_CATION_COUPLED_CHLORIDE_COTRANSPORTERS | 8.11e-04 | 7 | 89 | 2 | MM15081 | |
| Pathway | REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES | 8.40e-04 | 67 | 89 | 4 | MM15327 | |
| Pathway | REACTOME_SENSORY_PERCEPTION_OF_TASTE | 9.62e-04 | 31 | 89 | 3 | MM15691 | |
| Pathway | REACTOME_ION_CHANNEL_TRANSPORT | 1.05e-03 | 183 | 89 | 6 | M997 | |
| Pathway | WP_GPCRS_CLASS_A_RHODOPSINLIKE | 1.14e-03 | 186 | 89 | 6 | MM15994 | |
| Pathway | REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | 1.35e-03 | 76 | 89 | 4 | MM15072 | |
| Pathway | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 1.58e-03 | 270 | 89 | 7 | M15514 | |
| Pathway | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | 1.62e-03 | 37 | 89 | 3 | MM15067 | |
| Pathway | KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | 1.65e-03 | 272 | 89 | 7 | M13380 | |
| Pathway | REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | 1.88e-03 | 205 | 89 | 6 | M752 | |
| Pathway | REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | 1.95e-03 | 84 | 89 | 4 | M27334 | |
| Pathway | REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | 2.16e-03 | 144 | 89 | 5 | MM14501 | |
| Pathway | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 2.17e-03 | 211 | 89 | 6 | MM14502 | |
| Pathway | REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES | 2.22e-03 | 87 | 89 | 4 | M27617 | |
| Pathway | REACTOME_INDUCTION_OF_CELL_CELL_FUSION | 2.94e-03 | 13 | 89 | 2 | M46426 | |
| Pathway | WP_RETT_SYNDROME | 3.43e-03 | 48 | 89 | 3 | M39759 | |
| Pathway | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | 4.47e-03 | 16 | 89 | 2 | M26945 | |
| Pubmed | 5.54e-16 | 9 | 141 | 7 | 16382098 | ||
| Pubmed | Quantitation of HERV-K env gene expression and splicing in human breast cancer. | 1.02e-12 | 5 | 141 | 5 | 12629516 | |
| Pubmed | A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. | 6.10e-12 | 6 | 141 | 5 | 23652591 | |
| Pubmed | Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. | CACNA1A SCN11A KCNH7 GJA5 CLCN3 KCNQ5 SCN1A SCN3A SCN4A SCN8A SCN9A | 1.31e-11 | 139 | 141 | 11 | 16985003 |
| Pubmed | 1.27e-10 | 9 | 141 | 5 | 15746173 | ||
| Pubmed | Different evolutionary processes shaped the mouse and human olfactory receptor gene families. | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.32e-10 | 340 | 141 | 14 | 11875048 |
| Pubmed | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.32e-10 | 340 | 141 | 14 | 11802173 | |
| Pubmed | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.48e-10 | 343 | 141 | 14 | 32295537 | |
| Pubmed | OR8H2 OR8B4 OR5AK2 OR1S2 OR9Q1 OR2V1 OR5AK3P OR9A1P OR6C70 OR52E4 OR2V2 OR4D5 OR9A2 OR10A5 | 1.66e-10 | 346 | 141 | 14 | 14611657 | |
| Pubmed | A revised nomenclature for transcribed human endogenous retroviral loci. | ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-8 ERVK-18 ERVK-19 ERVK-25 ERVK-24 | 1.82e-10 | 94 | 141 | 9 | 21542922 |
| Pubmed | 2.59e-10 | 4 | 141 | 4 | 17537961 | ||
| Pubmed | 2.59e-10 | 4 | 141 | 4 | 35031483 | ||
| Pubmed | 2.59e-10 | 4 | 141 | 4 | 29578003 | ||
| Pubmed | 7.89e-10 | 12 | 141 | 5 | 14557543 | ||
| Pubmed | 1.28e-09 | 13 | 141 | 5 | 15123669 | ||
| Pubmed | 1.29e-09 | 5 | 141 | 4 | 8812438 | ||
| Pubmed | Early development of electrical excitability in the mouse enteric nervous system. | 1.29e-09 | 5 | 141 | 4 | 22875929 | |
| Pubmed | 1.29e-09 | 5 | 141 | 4 | 17724025 | ||
| Pubmed | 8.37e-09 | 18 | 141 | 5 | 18664271 | ||
| Pubmed | 8.97e-09 | 7 | 141 | 4 | 20231857 | ||
| Pubmed | 3.21e-08 | 9 | 141 | 4 | 8906617 | ||
| Pubmed | 3.21e-08 | 9 | 141 | 4 | 19228980 | ||
| Pubmed | 5.33e-08 | 10 | 141 | 4 | 20736995 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 19284629 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 12610651 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 33895391 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 23859570 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 18784617 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 10516026 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 17544618 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 32845893 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 28518218 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 17928448 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 14973256 | ||
| Pubmed | 6.52e-08 | 3 | 141 | 3 | 15302875 | ||
| Pubmed | 8.36e-08 | 11 | 141 | 4 | 12225896 | ||
| Pubmed | CACNA1A KCNH7 SLC4A8 ADGRL1 CBARP GRIK3 LRRTM1 SLC4A3 ADCYAP1R1 PTPRA SCN1A SCN9A | 1.09e-07 | 405 | 141 | 12 | 38187761 | |
| Pubmed | Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. | 1.25e-07 | 12 | 141 | 4 | 30175250 | |
| Pubmed | 1.25e-07 | 12 | 141 | 4 | 20584212 | ||
| Pubmed | Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains. | 1.34e-07 | 30 | 141 | 5 | 17273929 | |
| Pubmed | SLC4A8 GPR22 AQP9 CLDN8 SLC9A4 SLC12A3 SLCO4C1 SLC37A2 SLC6A14 | 2.29e-07 | 212 | 141 | 9 | 19521566 | |
| Pubmed | 2.51e-07 | 14 | 141 | 4 | 19059502 | ||
| Pubmed | 2.60e-07 | 4 | 141 | 3 | 21156207 | ||
| Pubmed | 2.60e-07 | 4 | 141 | 3 | 14681045 | ||
| Pubmed | Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. | 2.60e-07 | 4 | 141 | 3 | 10469592 | |
| Pubmed | Striatal α5 nicotinic receptor subunit regulates dopamine transmission in dorsal striatum. | 2.60e-07 | 4 | 141 | 3 | 22396410 | |
| Pubmed | 2.60e-07 | 4 | 141 | 3 | 35801810 | ||
| Pubmed | Use of recombinant inbred strains for studying genetic determinants of responses to alcohol. | 2.60e-07 | 4 | 141 | 3 | 8974318 | |
| Pubmed | Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse. | 3.41e-07 | 15 | 141 | 4 | 8838678 | |
| Pubmed | 4.54e-07 | 16 | 141 | 4 | 19259974 | ||
| Pubmed | 6.48e-07 | 5 | 141 | 3 | 1679748 | ||
| Pubmed | 6.48e-07 | 5 | 141 | 3 | 24337656 | ||
| Pubmed | No evidence for association between 19 cholinergic genes and bipolar disorder. | 9.57e-07 | 19 | 141 | 4 | 17373692 | |
| Pubmed | 1.29e-06 | 6 | 141 | 3 | 16029194 | ||
| Pubmed | Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone? | 1.29e-06 | 6 | 141 | 3 | 17513486 | |
| Pubmed | 1.29e-06 | 6 | 141 | 3 | 15063128 | ||
| Pubmed | 1.29e-06 | 6 | 141 | 3 | 23711479 | ||
| Pubmed | Diagnostic yield of genetic testing in epileptic encephalopathy in childhood. | 2.26e-06 | 7 | 141 | 3 | 25818041 | |
| Pubmed | Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans. | 2.26e-06 | 7 | 141 | 3 | 1505988 | |
| Pubmed | 2.26e-06 | 7 | 141 | 3 | 16828986 | ||
| Pubmed | Pain without nociceptors? Nav1.7-independent pain mechanisms. | 2.26e-06 | 7 | 141 | 3 | 24440715 | |
| Pubmed | 2.26e-06 | 7 | 141 | 3 | 23575686 | ||
| Pubmed | 3.60e-06 | 8 | 141 | 3 | 17559419 | ||
| Pubmed | 3.60e-06 | 8 | 141 | 3 | 25101983 | ||
| Pubmed | Sources of energy for gating by neurotransmitters in acetylcholine receptor channels. | 5.38e-06 | 9 | 141 | 3 | 22647603 | |
| Pubmed | 7.67e-06 | 10 | 141 | 3 | 27721237 | ||
| Pubmed | Common variants associated with general and MMR vaccine-related febrile seizures. | 7.67e-06 | 10 | 141 | 3 | 25344690 | |
| Pubmed | Autosomal Dominant Sleep-Related Hypermotor (Hyperkinetic) Epilepsy | 7.67e-06 | 10 | 141 | 3 | 20301348 | |
| Pubmed | 7.67e-06 | 10 | 141 | 3 | 12970426 | ||
| Pubmed | Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission. | 1.05e-05 | 11 | 141 | 3 | 29791835 | |
| Pubmed | 1.40e-05 | 12 | 141 | 3 | 8169823 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 32882268 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 29649454 | ||
| Pubmed | Modulation of gain-of-function α6*-nicotinic acetylcholine receptor by β3 subunits. | 1.63e-05 | 2 | 141 | 2 | 22315221 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 20346423 | ||
| Pubmed | Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy. | 1.63e-05 | 2 | 141 | 2 | 37901435 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 18079277 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 25823894 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 18790841 | ||
| Pubmed | An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior. | 1.63e-05 | 2 | 141 | 2 | 26410685 | |
| Pubmed | Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. | 1.63e-05 | 2 | 141 | 2 | 15684419 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 29351227 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 25972004 | ||
| Pubmed | Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice. | 1.63e-05 | 2 | 141 | 2 | 10827969 | |
| Pubmed | Orai1-Orai2 complex is involved in store-operated calcium entry in chondrocyte cell lines. | 1.63e-05 | 2 | 141 | 2 | 25769459 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 18055561 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 21502501 | ||
| Pubmed | Mitochondrial connexin40 regulates mitochondrial calcium uptake in coronary endothelial cells. | 1.63e-05 | 2 | 141 | 2 | 28122731 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 26740650 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 19694741 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 35348308 | ||
| Pubmed | Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus. | 1.63e-05 | 2 | 141 | 2 | 11245985 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 28851948 | ||
| Pubmed | Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization. | 1.63e-05 | 2 | 141 | 2 | 11248201 | |
| Pubmed | Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release. | 1.63e-05 | 2 | 141 | 2 | 26198171 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 28969560 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 15760941 | ||
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 26178077 | ||
| Pubmed | Differential expression of two sodium channel subtypes in human brain. | 1.63e-05 | 2 | 141 | 2 | 1317301 | |
| Pubmed | 1.63e-05 | 2 | 141 | 2 | 17322896 | ||
| Interaction | SCN11A interactions | 1.73e-08 | 15 | 117 | 5 | int:SCN11A | |
| Interaction | LGALS9B interactions | 2.28e-07 | 45 | 117 | 6 | int:LGALS9B | |
| Interaction | NALCN interactions | 1.03e-06 | 14 | 117 | 4 | int:NALCN | |
| Interaction | SSTR3 interactions | CACNA1A KCNH7 SLC4A8 ADGRL1 CBARP GRIK3 LRRTM1 SLC4A3 ADCYAP1R1 PTPRA SCN1A SCN9A | 3.11e-06 | 393 | 117 | 12 | int:SSTR3 |
| Interaction | SCN9A interactions | 5.98e-06 | 21 | 117 | 4 | int:SCN9A | |
| Interaction | SCN5A interactions | 7.64e-06 | 47 | 117 | 5 | int:SCN5A | |
| Interaction | SCN4B interactions | 1.05e-05 | 8 | 117 | 3 | int:SCN4B | |
| Interaction | CACNA1D interactions | 1.05e-05 | 24 | 117 | 4 | int:CACNA1D | |
| Interaction | MFSD5 interactions | 1.08e-05 | 86 | 117 | 6 | int:MFSD5 | |
| Interaction | OR4N2 interactions | 2.29e-05 | 29 | 117 | 4 | int:OR4N2 | |
| Interaction | SCN1A interactions | 2.29e-05 | 29 | 117 | 4 | int:SCN1A | |
| Interaction | SCN10A interactions | 3.04e-05 | 11 | 117 | 3 | int:SCN10A | |
| Interaction | B4GAT1 interactions | 4.41e-05 | 110 | 117 | 6 | int:B4GAT1 | |
| Interaction | ADGRE2 interactions | 4.92e-05 | 35 | 117 | 4 | int:ADGRE2 | |
| Interaction | CACNA1B interactions | 6.15e-05 | 37 | 117 | 4 | int:CACNA1B | |
| Interaction | LGALS8 interactions | 7.08e-05 | 174 | 117 | 7 | int:LGALS8 | |
| Interaction | CMTM5 interactions | 7.81e-05 | 239 | 117 | 8 | int:CMTM5 | |
| Interaction | NRN1 interactions | 8.39e-05 | 40 | 117 | 4 | int:NRN1 | |
| Interaction | GLRB interactions | 9.26e-05 | 41 | 117 | 4 | int:GLRB | |
| Interaction | GPR88 interactions | 1.01e-04 | 16 | 117 | 3 | int:GPR88 | |
| Interaction | YIPF3 interactions | 1.08e-04 | 186 | 117 | 7 | int:YIPF3 | |
| Interaction | GPR21 interactions | 1.09e-04 | 81 | 117 | 5 | int:GPR21 | |
| Interaction | SCN8A interactions | 2.02e-04 | 20 | 117 | 3 | int:SCN8A | |
| Interaction | OR52I1 interactions | 3.30e-04 | 5 | 117 | 2 | int:OR52I1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr2q24 | 4.47e-05 | 127 | 139 | 5 | chr2q24 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q12 | 9.30e-05 | 345 | 139 | 7 | chr11q12 | |
| Cytoband | 11q12.1 | 1.37e-04 | 161 | 139 | 5 | 11q12.1 | |
| Cytoband | 2q24 | 4.92e-04 | 11 | 139 | 2 | 2q24 | |
| Cytoband | 12p13 | 9.89e-04 | 64 | 139 | 3 | 12p13 | |
| Cytoband | 2q24.3 | 1.06e-03 | 16 | 139 | 2 | 2q24.3 | |
| GeneFamily | Sodium voltage-gated channel alpha subunits | 6.48e-15 | 9 | 105 | 7 | 1203 | |
| GeneFamily | Solute carriers | SLC4A7 SLC4A8 SLC39A9 SLC4A3 SLC7A14 RHAG SLC4A2 SLC5A3 SLC26A8 SLC9A4 SLC12A3 SLCO4C1 SLC12A4 SLC22A3 SLC37A2 SLC23A1 SLC6A14 | 1.18e-10 | 395 | 105 | 17 | 752 |
| GeneFamily | Cholinergic receptors nicotinic subunits | 1.85e-06 | 16 | 105 | 4 | 173 | |
| GeneFamily | ORAI calcium release-activated calcium modulators | 9.98e-05 | 3 | 105 | 2 | 668 | |
| GeneFamily | Olfactory receptors, family 9 | 3.10e-04 | 23 | 105 | 3 | 156 | |
| GeneFamily | Parkinson disease associated genes|ATPase orphan transporters | 3.30e-04 | 5 | 105 | 2 | 1213 | |
| GeneFamily | Anoctamins | 1.46e-03 | 10 | 105 | 2 | 865 | |
| GeneFamily | Taste 2 receptors | 1.49e-03 | 39 | 105 | 3 | 1162 | |
| GeneFamily | CD molecules|Membrane spanning 4-domains | 4.81e-03 | 18 | 105 | 2 | 958 | |
| GeneFamily | Gap junction proteins | 7.15e-03 | 22 | 105 | 2 | 314 | |
| Coexpression | MANNO_MIDBRAIN_NEUROTYPES_HGABA | CACNA1A SLC4A8 ADGRL1 GRIK3 SLC4A3 SLC7A14 SLITRK1 CHRNA4 SLC5A3 PIEZO2 LRFN5 SCN1A SCN2A SCN3A SCN8A SCN9A TMCO3 PCDH9 | 8.25e-06 | 1106 | 129 | 18 | M39071 |
| Coexpression | MANNO_MIDBRAIN_NEUROTYPES_HDA2 | CACNA1A CHRNA6 GRIK3 SLC4A3 SLITRK1 CHRNA4 CHRNB3 LRFN5 SCN2A SCN3A SCN8A SCN9A | 9.15e-06 | 513 | 129 | 12 | M39069 |
| Coexpression | MANNO_MIDBRAIN_NEUROTYPES_HSERT | CACNA1A SLC4A8 SLC4A3 SLC7A14 SLITRK1 CHRNA4 LRFN5 SCN2A SCN3A SCN9A PCDH9 | 1.46e-05 | 450 | 129 | 11 | M39072 |
| Coexpression | CUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE | 3.06e-05 | 179 | 129 | 7 | M39308 | |
| Coexpression | MANNO_MIDBRAIN_NEUROTYPES_HNBGABA | CACNA1A SLC4A3 SLC7A14 SLITRK1 CHRNA4 TSPAN9 LRFN5 SCN1A SCN2A SCN3A SCN8A SCN9A PCDH9 | 4.52e-05 | 703 | 129 | 13 | M39070 |
| CoexpressionAtlas | cerebral cortex | CACNA1A KCNH7 SLC4A8 GPR22 TMEM63C ADGRL1 CBARP GRIK3 LRRTM1 SLC4A3 SLC7A14 SLITRK1 CHRNA4 ADCYAP1R1 CNTNAP5 LRFN2 KCNQ5 SCN1A SCN2A SCN3A SCN8A PCDH9 KCNT1 | 1.28e-06 | 1428 | 112 | 23 | cerebral cortex |
| ToppCell | 5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | ATP13A4 TLCD4 DUOXA1 SLCO4C1 TMEM245 SCN1A SLC22A3 OCLN RNF145 PCDH9 SLC6A14 | 1.62e-11 | 199 | 129 | 11 | 2dc33804f6691d7c9682e6c9b885e945fb97fc36 |
| ToppCell | 3'-Parenchyma_lung-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 5.87e-09 | 195 | 129 | 9 | eec187c087e432417bc346c5d3ead72f58bf3215 | |
| ToppCell | Macroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic | 7.32e-09 | 200 | 129 | 9 | f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2 | |
| ToppCell | Macroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic | 7.32e-09 | 200 | 129 | 9 | cc3409518f8b436ea92deb955e81114b3f410ff7 | |
| ToppCell | Macroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic | 7.32e-09 | 200 | 129 | 9 | c24a3099e3d96d8b72f6d05286bb355d661a0377 | |
| ToppCell | Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09) | ATP13A4 GKN2 DUOXA1 TMEM245 SCN1A SLC22A3 RNF145 PCDH9 SLC6A14 | 7.32e-09 | 200 | 129 | 9 | acc771a902cf2f060c3eb9aedb72a256f5778a6c |
| ToppCell | Parenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type | ATP13A4 GKN2 DUOXA1 TMEM245 SCN1A SLC22A3 RNF145 PCDH9 SLC6A14 | 7.32e-09 | 200 | 129 | 9 | ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb |
| ToppCell | Macroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic | 7.32e-09 | 200 | 129 | 9 | 4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca | |
| ToppCell | Macroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic | 7.32e-09 | 200 | 129 | 9 | 310cd53db1c137f6af74e6ae682221d7ac27310c | |
| ToppCell | Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | ATP13A4 GKN2 DUOXA1 TMEM245 SCN1A SLC22A3 RNF145 PCDH9 SLC6A14 | 7.32e-09 | 200 | 129 | 9 | eb44d1f80ecaac3a022cd04ab16dc36151e45488 |
| ToppCell | Macroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic | 7.32e-09 | 200 | 129 | 9 | 961858738ce35db8760c8c2e136f8369bc444ccf | |
| ToppCell | droplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.48e-08 | 169 | 129 | 8 | f2e20049a17eee533d49bd5f24a51962d123d132 | |
| ToppCell | droplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.48e-08 | 169 | 129 | 8 | 4c6892551e9dec94fc62b3beab1e6d424639a1e9 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.70e-08 | 193 | 129 | 8 | be28070c049e7cb68bcd54f582226eb2f5e4bc1c | |
| ToppCell | 5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 9.70e-08 | 193 | 129 | 8 | 8646e573f2d2ff175f3d02bfdf214e65f3b614d3 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.70e-08 | 193 | 129 | 8 | 0c652ebe22ce5d2927599dd97ef1920547858395 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.70e-08 | 193 | 129 | 8 | 8689a70a33a7c3823dc647d41ac0160e7c3ae396 | |
| ToppCell | 3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.05e-07 | 195 | 129 | 8 | 6617abca0009ad3d8731f515f91ab275f9ea4c40 | |
| ToppCell | cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 1.05e-07 | 195 | 129 | 8 | 6867f9c56ea27a17c8c4099aae0d79903c3748a5 | |
| ToppCell | 3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.05e-07 | 195 | 129 | 8 | fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.05e-07 | 195 | 129 | 8 | ffbab350e67d9c4b66c0ab84550daec8b8139a27 | |
| ToppCell | 3'-Parenchyma_lung-Epithelial-Alveolar_epithelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.05e-07 | 195 | 129 | 8 | 3e24570def013d5b0b1ef1d7a5ced7dfd922590b | |
| ToppCell | cellseq-Epithelial-Epithelial_Alveolar-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 1.05e-07 | 195 | 129 | 8 | 955a0a7244cd7eaf006a39e1bd03333baf6f30a4 | |
| ToppCell | 5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.09e-07 | 196 | 129 | 8 | b1abecc0aafc09ca70a5fde624f2a998c4aa3341 | |
| ToppCell | Somatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 1.18e-07 | 198 | 129 | 8 | c01091ef18e096d792ea2a7a715764a5b215355f | |
| ToppCell | primary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 1.18e-07 | 198 | 129 | 8 | 6d18b45eda4014759e6dd282d78ffd28df8a6044 | |
| ToppCell | Biopsy_Control_(H.)-Epithelial-AT2|Biopsy_Control_(H.) / Sample group, Lineage and Cell type | 1.23e-07 | 199 | 129 | 8 | 5323d49d3be980605b3e609b7f03bddba6e50e8a | |
| ToppCell | distal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.28e-07 | 200 | 129 | 8 | a77087a393aad674d4aa457ca6c0077b0424053d | |
| ToppCell | Parenchyma_COVID-19-Epithelial-TX-AT2-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type | 1.28e-07 | 200 | 129 | 8 | cf1991853e10c562edae9a0d71a209f35b07db80 | |
| ToppCell | Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.28e-07 | 200 | 129 | 8 | 7618ae284625c5c121bcc00eb9f07e5b1e3adf23 | |
| ToppCell | Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09) | 1.28e-07 | 200 | 129 | 8 | 23b319bf7e5ae03e5baa777c951da9bfc97cca8c | |
| ToppCell | Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 2.58e-07 | 148 | 129 | 7 | 9fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c | |
| ToppCell | PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 4.57e-07 | 161 | 129 | 7 | bb9cb42882aaa4a1ecf9b480c0e7ac302f2c0d5d | |
| ToppCell | COVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type | 6.09e-07 | 168 | 129 | 7 | 88c2c574f428c2502b5fe099bd73b0758f668ef6 | |
| ToppCell | droplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 6.09e-07 | 168 | 129 | 7 | 0e99ecd94ab8e5372e30433d7d0aa76b4d54257a | |
| ToppCell | droplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 6.09e-07 | 168 | 129 | 7 | 34722e14f28313f2e4644b3c1861ef12958cee9f | |
| ToppCell | droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 7.71e-07 | 174 | 129 | 7 | 009e88a6c79689a5d88b0af50aa89aa03b33f800 | |
| ToppCell | PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 9.32e-07 | 179 | 129 | 7 | af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86 | |
| ToppCell | TCGA-Colorectal-Solid_Tissue_Normal|TCGA-Colorectal / Sample_Type by Project: Shred V9 | 1.00e-06 | 181 | 129 | 7 | 88f6f56f5f58b479d5db91b32c45934c045f88ea | |
| ToppCell | COVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations) | 1.12e-06 | 184 | 129 | 7 | 369b82f793deab672204558ae4e112cfa5aa9ccc | |
| ToppCell | PCW_13-14-Neuronal-Neuronal_postreplicative|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung | 1.20e-06 | 186 | 129 | 7 | cf96f880e6e22189593ce1357c55e65c34644559 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 1.25e-06 | 187 | 129 | 7 | 5df9e1f5ca32217af255e76e6fb5afa346337811 | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.25e-06 | 187 | 129 | 7 | 15d6e158562d7d85af3ceaf955439b379c8fce81 | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.25e-06 | 187 | 129 | 7 | f62074b631fd45ad299c69d71b09267b04d656ee | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.29e-06 | 188 | 129 | 7 | 32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081 | |
| ToppCell | Globus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32 | 1.39e-06 | 190 | 129 | 7 | 416de85d8841dac883faa6f5339b2fb461a09e82 | |
| ToppCell | 11.5-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class | 1.49e-06 | 192 | 129 | 7 | a77d3692ff02ef7e066a9bd9e22725055a25c4d4 | |
| ToppCell | Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor | 1.49e-06 | 192 | 129 | 7 | cc9911e182a289779a2612bc213daae5607689e7 | |
| ToppCell | kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 1.49e-06 | 192 | 129 | 7 | ee27d27e3d269764dbe8711d0b37ff9331a298a9 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.54e-06 | 193 | 129 | 7 | 461919ab422bc9d1fcff7a3a4757c75239041d7e | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.54e-06 | 193 | 129 | 7 | 0dd810ad900d3e586551622b2c1de39d76fd6a7f | |
| ToppCell | 3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.65e-06 | 195 | 129 | 7 | d9694db6bf239636d1335016878c98f6ee2eb0eb | |
| ToppCell | kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group | 1.65e-06 | 195 | 129 | 7 | a38d9dc6192aea673d96fda6b25e81223fda3abf | |
| ToppCell | ASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq | 1.71e-06 | 196 | 129 | 7 | 754b4202b617165c6994a0b5a9b1e486dccdd44d | |
| ToppCell | Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.71e-06 | 196 | 129 | 7 | 4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725 | |
| ToppCell | 3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.71e-06 | 196 | 129 | 7 | 83aeb96a33802949238d8a097086a1812201d1b5 | |
| ToppCell | 5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.71e-06 | 196 | 129 | 7 | 65e161fd672e37a5d10f28011bb422c4d7042d6a | |
| ToppCell | 3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 1.71e-06 | 196 | 129 | 7 | 006d783a530aa6e1e6545dcc2e6b00bb300fe070 | |
| ToppCell | Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.83e-06 | 198 | 129 | 7 | 8f25e8dff42bad8e779ca618bdb1cb1610667962 | |
| ToppCell | AT2_cells|World / lung cells shred on cell class, cell subclass, sample id | 1.83e-06 | 198 | 129 | 7 | 92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a | |
| ToppCell | Primary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types | 1.83e-06 | 198 | 129 | 7 | 4ca5ff320905ab4ff60ed90a5522227c782142a6 | |
| ToppCell | Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations | 1.83e-06 | 198 | 129 | 7 | e3e0aa3ef20b2370f5b133048510677aaa562dfa | |
| ToppCell | Biopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type | 1.89e-06 | 199 | 129 | 7 | 9a65acfe9bf500db72142469cf17bf0973540001 | |
| ToppCell | Biopsy_IPF-Epithelial-AT2|Biopsy_IPF / Sample group, Lineage and Cell type | 1.89e-06 | 199 | 129 | 7 | c841d475703d3489161fb7904526bd7563d5fb0f | |
| ToppCell | Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.95e-06 | 200 | 129 | 7 | 3c251ad03fbbdae91dfd9037880ba43adbb03807 | |
| ToppCell | distal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.95e-06 | 200 | 129 | 7 | f47bb79202a59404e4916993a1f59cffcf710320 | |
| ToppCell | Lung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09) | 1.95e-06 | 200 | 129 | 7 | c905451425d1c24773bb0ca69bcf0309b277d2f1 | |
| ToppCell | distal-Epithelial-Signaling_Alveolar_Epithelial_Type_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 1.95e-06 | 200 | 129 | 7 | b0e5c8b425f47833cdc00b5aa3734c8c980f0967 | |
| ToppCell | Parenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type | 1.95e-06 | 200 | 129 | 7 | 35c05cae30cd6b323d2662f1396ddeab08bc75fc | |
| ToppCell | 356C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells) | 5.80e-06 | 88 | 129 | 5 | 1ca0e16981e88030987412e12838a9797b97b9c9 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 7.57e-06 | 161 | 129 | 6 | 1b805f77790aeb8a71b08bfac2fe2eed7343258f | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 8.70e-06 | 165 | 129 | 6 | e2aebb2fe197151e019371b8960f76f0c2386f08 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 8.70e-06 | 165 | 129 | 6 | b087771499aeb31cc4a338d2d0a9392a4ec1ac45 | |
| ToppCell | renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group | 8.70e-06 | 165 | 129 | 6 | d8f8b088fd28a6b9dbd6b51bcaee42000e963321 | |
| ToppCell | facs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.01e-06 | 166 | 129 | 6 | 11b0ae82b3068ef91715dbdd49fe8e9791b4a480 | |
| ToppCell | Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32 | 9.01e-06 | 166 | 129 | 6 | 6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef | |
| ToppCell | facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 9.01e-06 | 166 | 129 | 6 | fcc1aec31ebd39432d4cb284dc8fadf34e3c566a | |
| ToppCell | 10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue | 9.65e-06 | 168 | 129 | 6 | 90f713dae3fcbd6ca801a019e3861c263ff3366b | |
| ToppCell | TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9 | 9.98e-06 | 169 | 129 | 6 | 41cb92b0558f0d5a3e511058efd9110258b88ee3 | |
| ToppCell | TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9 | 9.98e-06 | 169 | 129 | 6 | 91f4b6a14708e701b2af22989004282041777491 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.10e-05 | 172 | 129 | 6 | 08a3fe536b1b064c5ee7779bc2b1115a5963a26b | |
| ToppCell | 367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells) | 1.10e-05 | 172 | 129 | 6 | a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6 | |
| ToppCell | 367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells) | 1.10e-05 | 172 | 129 | 6 | 26006967d0c82f7bd9b36a18e97a1b93e856aa67 | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.10e-05 | 172 | 129 | 6 | 553701349444eb366df3c11f54bb093434f153c6 | |
| ToppCell | droplet-Lung-immune-endo-depleted-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.14e-05 | 173 | 129 | 6 | 3612772632ddf11eb48579cae9a8ccab6b3f1f52 | |
| ToppCell | droplet-Lung-immune-endo-depleted-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.14e-05 | 173 | 129 | 6 | 4dc261ebcdb9bdcfca1451da1bd254f0dc5de203 | |
| ToppCell | PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01) | 1.18e-05 | 174 | 129 | 6 | 59ccc5a82507463e0a316ba6286cb25ec1a4091b | |
| ToppCell | droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype | 1.18e-05 | 174 | 129 | 6 | e9e4532a474b4b0938a50ff85c9508aca53cd3ae | |
| ToppCell | COVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.18e-05 | 174 | 129 | 6 | 8393f0b43c767839c1630bcb952d62b42efc788d | |
| ToppCell | COVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type | 1.22e-05 | 175 | 129 | 6 | 1125f0d3a5b2388fa77a820dea0288e824d84a82 | |
| ToppCell | 5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.26e-05 | 176 | 129 | 6 | 116741fef5895ca85057d2d31eca9eba5764ab44 | |
| ToppCell | 5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.26e-05 | 176 | 129 | 6 | 5b707f58d164ee7a6a527dd5d053472ce9a631c1 | |
| ToppCell | droplet-Marrow-BM-30m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.26e-05 | 176 | 129 | 6 | 8e4600efeea095a92178cfd26d7c58db7dfc0c80 | |
| ToppCell | renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group | 1.30e-05 | 177 | 129 | 6 | dc846d0feb94d4c289553cc3ac9dac81d10409cb | |
| ToppCell | kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.30e-05 | 177 | 129 | 6 | c9e8149639551a4c8daa90fcb2b895fdcff2e2ba | |
| ToppCell | wk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung | 1.38e-05 | 179 | 129 | 6 | e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a | |
| ToppCell | renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group | 1.38e-05 | 179 | 129 | 6 | 666072c0e8448dbaec1683d18368ec2502453f90 | |
| ToppCell | 3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.43e-05 | 180 | 129 | 6 | 368ff7fcfd21ad248f96a83a8b191040ba7d8670 | |
| ToppCell | facs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.47e-05 | 181 | 129 | 6 | 1db1eb7d330a7e5090994007ae287e11f0a74450 | |
| ToppCell | facs-Heart-LV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.47e-05 | 181 | 129 | 6 | 06174ce9240c9261c0f51a1b0d875335d60722e5 | |
| Computational | Porins / transporters. | 4.17e-05 | 211 | 66 | 8 | MODULE_63 | |
| Computational | Membranal receptors. | ABCA1 IFITM1 SLC4A3 AQP9 CHRNA2 CHRNA4 RHAG CHRNB3 PROM1 SLC12A3 RRH MUSK | 6.16e-05 | 517 | 66 | 12 | MODULE_64 |
| Computational | Ion channels. | 6.66e-05 | 70 | 66 | 5 | MODULE_316 | |
| Computational | AcetylCholine receptors. | 7.67e-05 | 14 | 66 | 3 | MODULE_328 | |
| Computational | Genes in the cancer module 267. | 9.54e-05 | 15 | 66 | 3 | MODULE_267 | |
| Computational | Ion channels. | 5.82e-04 | 27 | 66 | 3 | MODULE_214 | |
| Drug | disopyramide | 1.19e-10 | 66 | 128 | 9 | CID000003114 | |
| Drug | pilsicainide | 1.74e-10 | 46 | 128 | 8 | CID000004820 | |
| Drug | Zonisamide | 3.30e-10 | 17 | 128 | 6 | DB00909 | |
| Drug | procaine | CACNA1A CHRNA6 PKD1L3 CHRNA2 CHRNA4 CHRNB3 ORAI1 SCN3A SCN4A SCN9A MUSK | 1.09e-09 | 153 | 128 | 11 | CID000004914 |
| Drug | sodium | ERVK-6 CHRNA6 KCNH7 SLC4A7 SLC4A8 GRIK3 SLC4A3 SLC7A14 CHRNA2 CHRNA4 SLC4A2 CLCN3 SLC12A3 ATP11B SLC12A4 GUCY2C SLC22A3 SCN2A SCN3A SCN4A SCN9A SLC23A1 SLC6A14 | 2.70e-09 | 944 | 128 | 23 | CID000000923 |
| Drug | NSC7524 | CACNA1A CHRNA6 GRIK3 PKD1L3 CHRNA2 CHRNA4 CHRNB3 SCN2A SCN3A SCN4A SCN9A | 6.80e-09 | 182 | 128 | 11 | CID000005657 |
| Drug | APETx1, Anthopleura elegantissima | 1.42e-08 | 6 | 128 | 4 | ctd:C475726 | |
| Drug | verapamil | CACNA1A CHRNA6 ABCA1 KCNH7 PKD1L3 CHRNA2 CHRNA4 CHRNB3 ORAI1 CLCN3 KCNQ5 SLC22A3 SCN3A SCN4A SCN9A MUSK | 1.70e-08 | 490 | 128 | 16 | CID000002520 |
| Drug | 1,2-dichlorohexafluorocyclobutane | 5.65e-08 | 37 | 128 | 6 | CID000009643 | |
| Drug | QX-222 | 1.25e-07 | 42 | 128 | 6 | CID000005014 | |
| Drug | tetradotoxin | CACNA1A CHRNA6 SCN11A GRIK3 CHRNA2 CHRNA4 ADCYAP1R1 CHRNB3 GUCY2C SCN2A SCN3A SCN4A SCN8A SCN9A | 1.38e-07 | 428 | 128 | 14 | CID000020382 |
| Drug | alpha-conotoxin SI | 1.61e-07 | 23 | 128 | 5 | CID000163979 | |
| Drug | Skpymrfamide | 1.61e-07 | 23 | 128 | 5 | CID000132661 | |
| Drug | N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide | 1.74e-07 | 3 | 128 | 3 | ctd:C561228 | |
| Drug | procyclidine | 2.03e-07 | 24 | 128 | 5 | CID000004919 | |
| Drug | amiloride | CACNA1A CHRNA6 SLC4A7 PKD1L3 CHRNA2 CHRNA4 CHRNB3 SLC4A2 ORAI1 SLC12A3 SCN4A SCN9A | 2.26e-07 | 315 | 128 | 12 | CID000016230 |
| Drug | PrBCM | 2.52e-07 | 25 | 128 | 5 | CID000037396 | |
| Drug | Dns-C6-Cho | 3.05e-07 | 11 | 128 | 4 | CID000124728 | |
| Drug | AC1L9NC9 | 3.05e-07 | 11 | 128 | 4 | CID000449642 | |
| Drug | dihydronereistoxin | 3.05e-07 | 11 | 128 | 4 | CID000121232 | |
| Drug | LJP 1082 | 3.05e-07 | 11 | 128 | 4 | CID003037609 | |
| Drug | bipinnatin-B | 3.05e-07 | 11 | 128 | 4 | CID000127363 | |
| Drug | beta-eudesmol | 3.11e-07 | 26 | 128 | 5 | CID000091457 | |
| Drug | bupropion | 3.70e-07 | 81 | 128 | 7 | CID000000444 | |
| Drug | AC1L9P8C | 4.56e-07 | 12 | 128 | 4 | CID000450864 | |
| Drug | SureCN373116 | 4.56e-07 | 12 | 128 | 4 | CID010085732 | |
| Drug | pentolinium | 4.60e-07 | 28 | 128 | 5 | CID000005849 | |
| Drug | nereistoxin | 6.55e-07 | 13 | 128 | 4 | CID000015401 | |
| Drug | 1-acetyl-4-methylpiperazine methiodide | 6.55e-07 | 13 | 128 | 4 | CID004392675 | |
| Drug | C-toxiferine-I | 6.55e-07 | 13 | 128 | 4 | CID005089093 | |
| Drug | bipinnatin-A | 6.55e-07 | 13 | 128 | 4 | CID000196603 | |
| Drug | bipinnatin-C | 6.55e-07 | 13 | 128 | 4 | CID000129977 | |
| Drug | nefiracetam | 7.24e-07 | 56 | 128 | 6 | CID000071157 | |
| Drug | 2,3-dichlorooctafluorobutane | 9.13e-07 | 14 | 128 | 4 | CID000078982 | |
| Drug | LNF 209 | 9.13e-07 | 14 | 128 | 4 | CID000132666 | |
| Drug | tropicamide | 9.26e-07 | 32 | 128 | 5 | CID000005593 | |
| Drug | anatoxin-a hydrochloride | 1.24e-06 | 15 | 128 | 4 | CID000135265 | |
| Drug | SAD-128 | 1.24e-06 | 15 | 128 | 4 | CID000162008 | |
| Drug | N-methylcytisine | 1.24e-06 | 15 | 128 | 4 | CID000234566 | |
| Drug | aa373 | 1.24e-06 | 15 | 128 | 4 | CID000191672 | |
| Drug | (-)-pictamine | 1.24e-06 | 15 | 128 | 4 | CID006918623 | |
| Drug | (-)-lepadin B | 1.24e-06 | 15 | 128 | 4 | CID006918624 | |
| Drug | UB-165 | 1.24e-06 | 15 | 128 | 4 | CID004694339 | |
| Drug | procainamide | CHRNA6 SCN11A CHRNA2 CHRNA4 CHRNB3 SLC22A3 SCN3A SCN4A SCN9A | 1.32e-06 | 190 | 128 | 9 | CID000004913 |
| Drug | 3-(trifluoromethyl)-3-(m-iodophenyl)diazirine | 1.65e-06 | 16 | 128 | 4 | CID000123866 | |
| Drug | AC1L2SVN | 1.65e-06 | 16 | 128 | 4 | CID000127922 | |
| Drug | benzoquinonium | 1.65e-06 | 16 | 128 | 4 | CID000009393 | |
| Drug | PNU-282,987 | 1.65e-06 | 16 | 128 | 4 | CID004655349 | |
| Drug | nicardipine | 1.67e-06 | 145 | 128 | 8 | CID000004473 | |
| Drug | mexiletine | 1.93e-06 | 66 | 128 | 6 | CID000004178 | |
| Drug | Nsc36388 | 2.14e-06 | 17 | 128 | 4 | CID000014954 | |
| Drug | AC1O8PVM | 2.74e-06 | 18 | 128 | 4 | CID000004989 | |
| Drug | ABT-594 | 2.74e-06 | 18 | 128 | 4 | CID003075702 | |
| Drug | AC1LCVGE | 2.74e-06 | 18 | 128 | 4 | CID000656712 | |
| Drug | Scorpion Venoms | 2.74e-06 | 18 | 128 | 4 | ctd:D012604 | |
| Drug | benzetimide | 2.74e-06 | 18 | 128 | 4 | CID000021846 | |
| Drug | AC1L9P88 | 3.46e-06 | 19 | 128 | 4 | CID000450860 | |
| Drug | 4-(N-maleimido)benzyltrimethylammonium | 3.46e-06 | 19 | 128 | 4 | CID000162425 | |
| Drug | isoarecolone | 3.46e-06 | 19 | 128 | 4 | CID000146970 | |
| Drug | beta-erythroidine | 3.46e-06 | 19 | 128 | 4 | CID000010074 | |
| Drug | perhydrohistrionicotoxin | 3.46e-06 | 19 | 128 | 4 | CID000107881 | |
| Drug | PNU-120596 | 3.46e-06 | 19 | 128 | 4 | CID000311434 | |
| Drug | N-methylscopolamine | 3.74e-06 | 42 | 128 | 5 | CID000004120 | |
| Drug | heptanol | 3.74e-06 | 42 | 128 | 5 | CID000008129 | |
| Drug | gallamin | 4.21e-06 | 43 | 128 | 5 | CID000067425 | |
| Drug | lamotrigine | 4.22e-06 | 116 | 128 | 7 | CID000003878 | |
| Drug | quindine | 4.24e-06 | 219 | 128 | 9 | CID000001065 | |
| Drug | AC1Q5X7V | 4.31e-06 | 20 | 128 | 4 | CID000050190 | |
| Drug | 3-(2-azetidinylmethoxy)pyridine | 4.31e-06 | 20 | 128 | 4 | CID000001962 | |
| Drug | Dichloride, Alcuronium | 4.31e-06 | 20 | 128 | 4 | CID003032788 | |
| Drug | dinotefuran | 5.30e-06 | 21 | 128 | 4 | CID000197701 | |
| Drug | meproadifen | 5.30e-06 | 21 | 128 | 4 | CID000189752 | |
| Drug | philanthotoxin | 5.30e-06 | 45 | 128 | 5 | CID000115201 | |
| Drug | ipratropium bromide | 5.92e-06 | 46 | 128 | 5 | CID000003746 | |
| Drug | fluorocyclobutane | 5.98e-06 | 7 | 128 | 3 | CID011051569 | |
| Drug | suberyldicholine | 6.45e-06 | 22 | 128 | 4 | CID000123989 | |
| Drug | AR-R17779 | 6.45e-06 | 22 | 128 | 4 | CID005310971 | |
| Drug | histrionicotoxin | 6.45e-06 | 22 | 128 | 4 | CID005282247 | |
| Drug | clothianidin | 6.45e-06 | 22 | 128 | 4 | CID000213027 | |
| Drug | edrophonium | 7.32e-06 | 48 | 128 | 5 | CID000003202 | |
| Drug | AC1L3BL8 | 7.77e-06 | 23 | 128 | 4 | CID000086457 | |
| Drug | alpha-conotoxin ImI | 7.77e-06 | 23 | 128 | 4 | CID000133011 | |
| Drug | CID6325740 | 7.77e-06 | 23 | 128 | 4 | CID006325740 | |
| Drug | ABT-418 | 7.77e-06 | 23 | 128 | 4 | CID000119380 | |
| Drug | strychnine HCl | 8.67e-06 | 181 | 128 | 8 | CID000005304 | |
| Drug | anabaseine | 9.28e-06 | 24 | 128 | 4 | CID000018985 | |
| Drug | AC1L2IZE | 9.28e-06 | 24 | 128 | 4 | CID000072928 | |
| Drug | intruder | 9.28e-06 | 24 | 128 | 4 | CID000213021 | |
| Drug | 2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate | 9.52e-06 | 8 | 128 | 3 | ctd:C489827 | |
| Drug | neostigmine | 9.76e-06 | 87 | 128 | 6 | CID000004456 | |
| Drug | tetracaine | 1.04e-05 | 88 | 128 | 6 | CID000005411 | |
| Drug | anabasine | 1.10e-05 | 25 | 128 | 4 | CID000002181 | |
| Drug | varenicline | 1.10e-05 | 25 | 128 | 4 | CID000170361 | |
| Drug | pempidine | 1.10e-05 | 25 | 128 | 4 | CID000006603 | |
| Drug | benzquinamide | 1.29e-05 | 26 | 128 | 4 | CID000002342 | |
| Drug | curarine | 1.29e-05 | 26 | 128 | 4 | CID000198004 | |
| Drug | imidazolidine | 1.29e-05 | 26 | 128 | 4 | CID000449488 | |
| Drug | potassium | CACNA1A CHRNA6 KCNH7 PKD1L3 CHRNA2 CHRNA4 CHRNB3 ORAI1 CLCN3 SLC12A3 KCNQ5 ATP11B SLC12A4 GUCY2C SCN2A SCN3A SCN4A SCN9A | 1.40e-05 | 1008 | 128 | 18 | CID000000813 |
| Drug | pyridostigmine | 1.43e-05 | 93 | 128 | 6 | CID000004991 | |
| Drug | methylcarbamylcholine | 1.51e-05 | 27 | 128 | 4 | CID000004136 | |
| Disease | generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology) | 3.25e-15 | 10 | 130 | 7 | DOID:0111294 (implicated_via_orthology) | |
| Disease | Dravet syndrome (implicated_via_orthology) | 3.25e-15 | 10 | 130 | 7 | DOID:0080422 (implicated_via_orthology) | |
| Disease | generalized epilepsy with febrile seizures plus (implicated_via_orthology) | 2.13e-14 | 12 | 130 | 7 | DOID:0060170 (implicated_via_orthology) | |
| Disease | epilepsy (implicated_via_orthology) | CACNA1A SCN11A KCNH7 SLC12A3 SLC12A4 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A KCNT1 | 8.81e-12 | 163 | 130 | 12 | DOID:1826 (implicated_via_orthology) |
| Disease | Autosomal dominant nocturnal frontal lobe epilepsy | 3.33e-07 | 4 | 130 | 3 | cv:C3696898 | |
| Disease | anemia (implicated_via_orthology) | 4.73e-07 | 15 | 130 | 4 | DOID:2355 (implicated_via_orthology) | |
| Disease | congenital myasthenic syndrome (implicated_via_orthology) | 6.28e-07 | 16 | 130 | 4 | DOID:3635 (implicated_via_orthology) | |
| Disease | anxiety disorder (implicated_via_orthology) | 2.47e-06 | 22 | 130 | 4 | DOID:2030 (implicated_via_orthology) | |
| Disease | Seizure, Febrile, Simple | 2.89e-06 | 7 | 130 | 3 | C0149886 | |
| Disease | Seizure, Febrile, Complex | 2.89e-06 | 7 | 130 | 3 | C0751057 | |
| Disease | Autosomal Dominant Nocturnal Frontal Lobe Epilepsy | 2.89e-06 | 7 | 130 | 3 | C3696898 | |
| Disease | Febrile Convulsions | 6.88e-06 | 9 | 130 | 3 | C0009952 | |
| Disease | Generalized Epilepsy with Febrile Seizures Plus | 6.88e-06 | 9 | 130 | 3 | C3502809 | |
| Disease | cocaine use | 1.34e-05 | 11 | 130 | 3 | C3496069 | |
| Disease | TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) | 1.79e-05 | 12 | 130 | 3 | C1861063 | |
| Disease | Early Infantile Epileptic Encephalopathy 6 | 1.93e-05 | 2 | 130 | 2 | C4551549 | |
| Disease | Infantile Severe Myoclonic Epilepsy | 2.31e-05 | 13 | 130 | 3 | C0751122 | |
| Disease | MMR-related febrile seizures | 3.66e-05 | 15 | 130 | 3 | EFO_0006519 | |
| Disease | B Virus Infection | 5.76e-05 | 3 | 130 | 2 | C0037140 | |
| Disease | Benign familial infantile epilepsy | 5.76e-05 | 3 | 130 | 2 | cv:C5575231 | |
| Disease | Postherpetic neuralgia | 5.76e-05 | 3 | 130 | 2 | C0032768 | |
| Disease | Herpesviridae Infections | 5.76e-05 | 3 | 130 | 2 | C0019372 | |
| Disease | Primary Erythermalgia | 5.76e-05 | 3 | 130 | 2 | C0014805 | |
| Disease | Familial or sporadic hemiplegic migraine | 5.76e-05 | 3 | 130 | 2 | cv:CN295307 | |
| Disease | Familial hemiplegic migraine | 5.76e-05 | 3 | 130 | 2 | cv:C0338484 | |
| Disease | Epilepsies, Partial | 5.76e-05 | 3 | 130 | 2 | C0014547 | |
| Disease | PAROXYSMAL EXTREME PAIN DISORDER | 5.76e-05 | 3 | 130 | 2 | C1833661 | |
| Disease | Febrile seizure (within the age range of 3 months to 6 years) | 6.50e-05 | 18 | 130 | 3 | HP_0002373 | |
| Disease | Frontal Epilepsy, Benign, Childhood | 1.15e-04 | 4 | 130 | 2 | C0393671 | |
| Disease | Epilepsy, Cingulate | 1.15e-04 | 4 | 130 | 2 | C0393684 | |
| Disease | Epilepsy, Supplementary Motor | 1.15e-04 | 4 | 130 | 2 | C0393683 | |
| Disease | Epilepsy, Opercular | 1.15e-04 | 4 | 130 | 2 | C0393688 | |
| Disease | unipolar depression, smoking behaviour measurement | 1.15e-04 | 4 | 130 | 2 | EFO_0003761, EFO_0005671 | |
| Disease | juvenile-onset Parkinson's disease (implicated_via_orthology) | 1.15e-04 | 4 | 130 | 2 | DOID:0060893 (implicated_via_orthology) | |
| Disease | Epilepsy, Orbito-Frontal | 1.15e-04 | 4 | 130 | 2 | C0751643 | |
| Disease | Epilepsy, Anterior Fronto-Polar | 1.15e-04 | 4 | 130 | 2 | C0751642 | |
| Disease | Kufor-Rakeb syndrome (implicated_via_orthology) | 1.15e-04 | 4 | 130 | 2 | DOID:0060556 (implicated_via_orthology) | |
| Disease | Epilepsy, Frontal Lobe | 1.15e-04 | 4 | 130 | 2 | C0085541 | |
| Disease | cigarettes per day measurement | 1.46e-04 | 438 | 130 | 9 | EFO_0006525 | |
| Disease | sensory perception of bitter taste | 2.02e-04 | 26 | 130 | 3 | GO_0050913 | |
| Disease | Familial benign neonatal epilepsy | 2.86e-04 | 6 | 130 | 2 | C0220669 | |
| Disease | Congenital Pain Insensitivity | 3.99e-04 | 7 | 130 | 2 | C0002768 | |
| Disease | Hereditary Sensory Autonomic Neuropathy, Type 5 | 3.99e-04 | 7 | 130 | 2 | C0020075 | |
| Disease | Early Childhood Epilepsy, Myoclonic | 5.30e-04 | 8 | 130 | 2 | C0393695 | |
| Disease | Idiopathic Myoclonic Epilepsy | 5.30e-04 | 8 | 130 | 2 | C0338478 | |
| Disease | Symptomatic Myoclonic Epilepsy | 5.30e-04 | 8 | 130 | 2 | C0338479 | |
| Disease | Benign Infantile Myoclonic Epilepsy | 5.30e-04 | 8 | 130 | 2 | C0751120 | |
| Disease | Myoclonic Encephalopathy | 5.30e-04 | 8 | 130 | 2 | C0438414 | |
| Disease | Myoclonic Absence Epilepsy | 5.30e-04 | 8 | 130 | 2 | C0393703 | |
| Disease | alcohol use disorder measurement, longitudinal alcohol consumption measurement | 5.82e-04 | 37 | 130 | 3 | EFO_0007645, EFO_0009458 | |
| Disease | Myoclonic Epilepsy | 6.80e-04 | 9 | 130 | 2 | C0014550 | |
| Disease | Epilepsy, Myoclonic, Infantile | 8.47e-04 | 10 | 130 | 2 | C0917800 | |
| Disease | long QT syndrome (implicated_via_orthology) | 8.47e-04 | 10 | 130 | 2 | DOID:2843 (implicated_via_orthology) | |
| Disease | reading | 9.07e-04 | 43 | 130 | 3 | EFO_0005229 | |
| Disease | Myoclonic Astatic Epilepsy | 1.03e-03 | 11 | 130 | 2 | C0393702 | |
| Disease | response to antidepressant | 1.12e-03 | 176 | 130 | 5 | GO_0036276 | |
| Disease | Retinitis Pigmentosa | 1.18e-03 | 104 | 130 | 4 | C0035334 | |
| Disease | prediabetes syndrome (biomarker_via_orthology) | 1.24e-03 | 12 | 130 | 2 | DOID:11716 (biomarker_via_orthology) | |
| Disease | Bipolar Disorder | 1.28e-03 | 477 | 130 | 8 | C0005586 | |
| Disease | Epilepsy | 1.40e-03 | 109 | 130 | 4 | C0014544 | |
| Disease | neuronal ceroid lipofuscinosis (implicated_via_orthology) | 1.69e-03 | 14 | 130 | 2 | DOID:14503 (implicated_via_orthology) | |
| Disease | unipolar depression, mood disorder, response to antidepressant | 1.69e-03 | 14 | 130 | 2 | EFO_0003761, EFO_0004247, GO_0036276 | |
| Disease | 3-hydroxyphenylacetic acid measurement | 1.69e-03 | 14 | 130 | 2 | EFO_0010448 | |
| Disease | alcohol use disorder (implicated_via_orthology) | 1.76e-03 | 195 | 130 | 5 | DOID:1574 (implicated_via_orthology) | |
| Disease | omega-6 polyunsaturated fatty acid measurement | 1.84e-03 | 197 | 130 | 5 | EFO_0005680 | |
| Disease | Schizophrenia | ABCA1 PSEN2 MC5R GRIK3 LRRTM1 CHRNA4 ADCYAP1R1 SLC26A8 PTPRA TMEM245 ERVK-8 | 1.86e-03 | 883 | 130 | 11 | C0036341 |
| Disease | interleukin 18 receptor 1 measurement | 1.95e-03 | 15 | 130 | 2 | EFO_0008178 | |
| Disease | soluble triggering receptor expressed on myeloid cells 2 measurement | 2.04e-03 | 296 | 130 | 6 | EFO_0010151 | |
| Disease | sleep duration, high density lipoprotein cholesterol measurement | 2.05e-03 | 121 | 130 | 4 | EFO_0004612, EFO_0005271 | |
| Disease | Tremor, Rubral | 2.22e-03 | 16 | 130 | 2 | C0750940 | |
| Disease | Ataxia, Appendicular | 2.22e-03 | 16 | 130 | 2 | C0750937 | |
| Disease | Ataxia, Motor | 2.22e-03 | 16 | 130 | 2 | C0278161 | |
| Disease | vitamin C measurement | 2.22e-03 | 16 | 130 | 2 | EFO_0600003 | |
| Disease | Ataxia, Sensory | 2.22e-03 | 16 | 130 | 2 | C0240991 | |
| Disease | Abnormal coordination | 2.22e-03 | 16 | 130 | 2 | C0520966 | |
| Disease | Ataxia, Truncal | 2.22e-03 | 16 | 130 | 2 | C0427190 | |
| Disease | Drug-induced agranulocytosis | 2.22e-03 | 16 | 130 | 2 | HP_0012235 | |
| Disease | Early infantile epileptic encephalopathy with suppression bursts | 2.22e-03 | 16 | 130 | 2 | C0393706 | |
| Disease | level of Phosphatidylcholine (18:0_20:3) in blood serum | 2.22e-03 | 16 | 130 | 2 | OBA_2045093 | |
| Disease | Dystonia, Limb | 2.51e-03 | 17 | 130 | 2 | C0751093 | |
| Disease | Dystonia, Diurnal | 2.51e-03 | 17 | 130 | 2 | C0393610 | |
| Disease | DNA methylation | 2.55e-03 | 656 | 130 | 9 | GO_0006306 | |
| Disease | Dystonia, Paroxysmal | 2.81e-03 | 18 | 130 | 2 | C0393588 | |
| Disease | smoking cessation | 3.25e-03 | 325 | 130 | 6 | EFO_0004319 | |
| Disease | triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement | 3.26e-03 | 225 | 130 | 5 | EFO_0008317, EFO_0020947 | |
| Disease | phospholipid measurement | 3.48e-03 | 140 | 130 | 4 | EFO_0004639 | |
| Disease | level of Phosphatidylcholine (18:1_20:4) in blood serum | 3.83e-03 | 21 | 130 | 2 | OBA_2045104 | |
| Disease | progranulin measurement | 4.20e-03 | 22 | 130 | 2 | EFO_0004625 | |
| Disease | very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio | 4.22e-03 | 239 | 130 | 5 | EFO_0008317, EFO_0020945 | |
| Disease | Retinitis pigmentosa | 4.31e-03 | 74 | 130 | 3 | cv:C0035334 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VLLVVVMSLFVGGTL | 46 | Q8N350 | |
| VMDFVVVLTGILATV | 171 | O00555 | |
| VVATMILLIIVFAIF | 166 | O43315 | |
| LFTMIFVTLSIVITV | 311 | P43681 | |
| LFIMIFVTLSIIVTV | 301 | Q05901 | |
| AILVFILIFMETQIT | 1001 | P04920 | |
| VLILIFMETQITALI | 996 | P48751 | |
| ELVILETIMLQTLGF | 131 | O60583 | |
| IFTLIAVIMGLIAVT | 356 | O42043 | |
| FIFTLIAVIMGLIAV | 466 | O71037 | |
| FIFTLIAVIMGLIAV | 466 | Q902F8 | |
| IFTLIAVIMGLIAVT | 466 | Q9UKH3 | |
| FLVFLNTIILMVEIE | 116 | Q96P56 | |
| SFVGMLTITDFILVL | 236 | Q9UGI9 | |
| IDLAIILVVVFTMSL | 971 | Q9H7F0 | |
| MLIIVLVNAFVSITV | 1146 | Q9H7F0 | |
| IVIMLSLNFIVSLVA | 1111 | Q4VNC1 | |
| VSFVIVVNLVFLMVT | 1011 | O94910 | |
| MAVEGVVFFLITVLI | 1856 | O95477 | |
| VIFLLNVSMFIVVLV | 796 | Q8IZP9 | |
| MIFVTLSIVITVFVL | 336 | Q15822 | |
| VSGIFFMISLVITAV | 551 | Q9BYT9 | |
| FMISLVITAVFGVVV | 556 | Q9BYT9 | |
| ILMIAVFTLTGAVVL | 431 | P25092 | |
| IIVSAILGIMVFIAT | 176 | Q16625 | |
| GMISIISNIIVLGIF | 36 | O14718 | |
| LVFFIVVGVITMLSS | 196 | Q96RC9 | |
| TIIMVPVGLIFVVFT | 201 | Q96SN7 | |
| IIVASVLVFIIILMI | 536 | Q96NI6 | |
| IAFLLAVMTLIVTLF | 196 | A6NIJ9 | |
| AVMTLIVTLFLVILS | 201 | A6NIJ9 | |
| GLMVISYIIVDVILI | 201 | Q8NGH9 | |
| LVFSVIEMVFIGVQT | 196 | Q7RTS5 | |
| EILIFIIVGSTLMVS | 196 | Q8N162 | |
| EVLIIMFAIFVIPAS | 196 | Q8NGQ5 | |
| GTMALIFSFLIVVLV | 431 | Q86UE6 | |
| LIVDIMFIIDILINF | 456 | Q9NS40 | |
| LILEFVMIVVFGLEF | 161 | Q9NR82 | |
| QVIVAIISFLETMLL | 161 | Q5JUK3 | |
| TIMVPFGLIFIVFAV | 241 | Q96D31 | |
| STLLIAMVIAFVGIF | 691 | Q9P1W3 | |
| LTGVLVVMLIFTVLE | 181 | Q9GZW8 | |
| IEIGVMVFGTSLVII | 196 | Q8NHC6 | |
| MVFGTSLVIISFVVI | 201 | Q8NHC6 | |
| LVLFSAVMVVFTVAL | 26 | Q8NHB1 | |
| LVLFSVVMAVFTVAL | 26 | Q96R30 | |
| AGAMVVIVVIFVTVL | 821 | Q9HC56 | |
| GMTVGIVASLLIIIF | 191 | O14524 | |
| ILSVIVFGSIVLLML | 481 | O60337 | |
| VIVASVLVFIFVLLM | 546 | Q9BTN0 | |
| VLFLGILITLMTFSI | 161 | Q9H3V2 | |
| ILITLMTFSIIELFI | 166 | Q9H3V2 | |
| VSIIFMIAVTFAIVL | 521 | Q5XXA6 | |
| FEKVIFGILTVMSIQ | 586 | Q6NUT2 | |
| MVLFSLVLFTVAIIG | 481 | P49961 | |
| FIFTLIAVIMGLIAV | 1226 | P63135 | |
| SIMVNFVLFIGIIVI | 316 | P41586 | |
| SLSVIEMILAAIFFV | 51 | Q04941 | |
| IILDVVFVGFDLMFT | 196 | Q8NH89 | |
| VFVGFDLMFTELVII | 201 | Q8NH89 | |
| MINELVLFIVGLSVI | 206 | Q8NGQ3 | |
| EFILFLMAVFIIIGS | 196 | Q8NGU1 | |
| IMLLVVFVGSNLIFT | 196 | Q8NH90 | |
| QVLLGILVVTFSMVA | 41 | P81408 | |
| IITAVMGVITFLFLI | 216 | Q8TED4 | |
| MIFVTLSIVVTVFVL | 311 | Q15825 | |
| MKILVAFLVVLTIFG | 1 | Q86XP6 | |
| IVILIFIMTGIDLKF | 41 | D3W0D1 | |
| IFTLIAVIMGLIAVT | 356 | P61566 | |
| FIFTLIAVIMGLIAV | 466 | P61570 | |
| FIFTLIAVIMGLIAV | 466 | Q69384 | |
| IFTLIAVIMGLIAVT | 356 | P61567 | |
| LTVLFIFRMLVLGTA | 26 | P36382 | |
| IVFAVMLSILSLIGI | 361 | Q5VWK5 | |
| IFTLIAVIMGLIAVT | 466 | P61565 | |
| MGIAVEVFLTLGVIS | 36 | P33032 | |
| QITLSAIMIFILFVS | 81 | Q9BZJ6 | |
| VDTFRGIALILMVFV | 271 | Q68CP4 | |
| FIFTLIAVIMGLIAV | 466 | Q902F9 | |
| KTIFIIFMLVVGLIS | 206 | P35212 | |
| GVVLTLLSIFVRVME | 11 | Q9Y5L2 | |
| FFIILLGIIFEIILM | 41 | Q8NDH2 | |
| LIVTTVLEEPFVMFR | 436 | Q13003 | |
| QIPIFFFTVVVMLIT | 216 | Q99680 | |
| SIIMIFLTALATFIV | 26 | Q1HG43 | |
| IVGIVIQMFFTLGII | 241 | O75751 | |
| SLVLGFVFMLLVDQI | 111 | Q9NUM3 | |
| VAVFALMLIITLVSV | 661 | Q16820 | |
| SLAVLIVVFSLFMLT | 316 | Q6N075 | |
| VVIFIIFCIIGIMTR | 1246 | Q8WYK1 | |
| FMTVVGNLLIVVIVT | 36 | Q8NGN0 | |
| MVALSSLLVIVFIII | 156 | P18433 | |
| FEIYAIVGTILVVMI | 196 | Q9H207 | |
| TEFILFLMAVFILIG | 191 | Q8NGT5 | |
| MTIGFILLLVFGSVT | 96 | P13164 | |
| FVSISFIVLMIISLA | 211 | Q9ULK6 | |
| MLRVVEGIFIFVVVS | 1 | Q9NYW0 | |
| MGGVIKSIFTFVLIV | 1 | Q9NYV8 | |
| MITFLPIIFSILVVV | 1 | P59539 | |
| METAVIGVVVVLFVV | 16 | A0A1B0GVQ0 | |
| DFAVFLTIVIMVTID | 861 | Q9Y6M7 | |
| INIVLTIMTGAFIVI | 151 | Q7Z5M5 | |
| VFTGIFTAEMVLKLI | 616 | P35499 | |
| ILGISAFIFLMLTVT | 501 | Q6UWJ1 | |
| AFIFLMLTVTELLDV | 506 | Q6UWJ1 | |
| IEFPMELFLIIGFTV | 306 | Q96RN1 | |
| ILMIIVVLTFVFGAN | 496 | O43490 | |
| GTFLILTSVILMVLV | 1651 | Q7Z443 | |
| ILMTVVGTIFVIILA | 201 | Q68DV7 | |
| FDFVVVIISIVGMFL | 1581 | Q15858 | |
| VIISIVGMFLADLIE | 1586 | Q15858 | |
| VSETLIFIFMGVSTV | 361 | Q6AI14 | |
| LLADEVITVFSVVGM | 326 | Q9Y371 | |
| FIIVVPGMISRILFT | 311 | P53794 | |
| IFDFVVVILSIVGMF | 1591 | Q9NY46 | |
| LTIFTMVIIDFLIGV | 736 | Q2Y0W8 | |
| TIFLTFMTLVVFVGV | 256 | Q9UP95 | |
| IFDFVVVILSIVGMF | 1606 | P35498 | |
| VVILSIVGMFLAELI | 1611 | P35498 | |
| TAGIIFIITGMVVLI | 121 | P56748 | |
| IITAVFLSVVAILAM | 86 | Q8IZ96 | |
| VTTVFMLIVSVLALI | 86 | Q9UBR5 | |
| VILFSAILIVLTMVG | 101 | P58418 | |
| ALIFKIIMTVFTFGI | 506 | P51790 | |
| FGTLVFTVMVITVTV | 1001 | Q9Y2G3 | |
| VVLMVLLISTLVFVI | 601 | Q8TBB6 | |
| TLVFGLFMGLVLVVI | 196 | Q9H1E5 | |
| FLVLMVSLVLVTLVA | 6 | Q8WWY7 | |
| SVVVVFFLSGILSMI | 286 | Q92544 | |
| LVFVTSAFTVVGMLV | 626 | Q96PX8 | |
| QILIVLLTTEMFVGG | 491 | Q9UHI7 | |
| IVIIFTFMAGTPITV | 586 | Q6ZQN7 | |
| LTFPRIVFMLGFVVV | 251 | Q9NPG8 | |
| IVFMLGFVVVLSFLL | 256 | Q9NPG8 | |
| IFDFVVVILSIVGMF | 1596 | Q99250 | |
| VVILSIVGMFLAELI | 1601 | Q99250 | |
| VLMFLADTVDFIIIV | 2191 | Q9H5I5 | |
| IFLGSFVLSLLTIMV | 91 | Q8NCL8 | |
| ISVIVVMTIFLVVLY | 146 | P49810 | |
| VLEIAMIVLFGLFVE | 11 | Q02094 | |
| NGILMTVVFFIVRIA | 176 | Q96MV1 | |
| LFGAIISVVIMFLLT | 571 | P55017 | |
| NIFDFVVVILSIVGM | 1586 | Q9UQD0 | |
| VVVILSIVGMFLADI | 1591 | Q9UQD0 | |
| ALRIFIMFDVLTVTG | 281 | A6NFE2 | |
| LNLVIMAVVIFSVLF | 231 | Q9BXA5 | |
| IPVFLVIVFLMSVGT | 241 | Q9H330 | |
| VVLVIVIFIFSVVGM | 706 | Q9UI33 | |
| VLRDVIFIGLMVLSS | 191 | Q8TDU5 | |
| GVGITMVLISIFVTI | 116 | Q9UN76 | |
| LFIVVASILQSMLEI | 346 | Q96MT1 | |
| LVIAIGTIVMVTGFL | 56 | O75954 | |
| LIDFNLLMVTTIVLG | 121 | Q9GZU3 | |
| LFAVLTIFILLIMEG | 796 | Q9Y487 | |
| VTTLFFIIMGIISLT | 66 | Q8NHV5 | |
| IIVATLLVFIVILMV | 541 | Q9ULH4 | |
| VIISIMSSFAIFVLL | 496 | O15146 |