Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1B TMEM241 ATP13A1 SLC5A9 SLC2A3 RHCE RHD ITPR1 ITPR2 MFSD14A GJB5 KCNA7 SLC44A5 CATSPER2 KCNC3 SLC5A6 SLC22A2 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11 DISP1	4.69e-07	1180	111	22	GO:0022857
GeneOntologyMolecularFunction	transporter activity	CACNA1B TMEM241 ATP13A1 SLC5A9 SLC2A3 RHCE RHD ITPR1 ITPR2 MFSD14A GJB5 KCNA7 SLC44A5 CATSPER2 KCNC3 SLC5A6 SLC22A2 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11 DISP1	2.04e-06	1289	111	22	GO:0005215
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1B ATP13A1 SLC5A9 RHCE RHD ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3	9.97e-06	627	111	14	GO:0022890
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1B ATP13A1 SLC5A9 RHCE RHD ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11	1.96e-05	758	111	15	GO:0015318
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1B ATP13A1 SLC5A9 ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP1A3	5.66e-05	465	111	11	GO:0046873
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR2	9.15e-05	3	111	2	GO:0005220
GeneOntologyMolecularFunction	channel activity	CACNA1B RHCE RHD ITPR1 ITPR2 GJB5 KCNA7 CATSPER2 KCNC3 KCNJ13 SLC26A11	1.65e-04	525	111	11	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1B RHCE RHD ITPR1 ITPR2 GJB5 KCNA7 CATSPER2 KCNC3 KCNJ13 SLC26A11	1.68e-04	526	111	11	GO:0022803
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1B ATP13A1 SLC5A9 ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3	3.24e-04	664	111	12	GO:0008324
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1B ATP13A1 SLC5A9 ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11	4.60e-04	793	111	13	GO:0015075
GeneOntologyMolecularFunction	choline transmembrane transporter activity	SLC44A5 SLC22A2	8.39e-04	8	111	2	GO:0015220
GeneOntologyMolecularFunction	kinase binding	SPDYE17 SPDYE10 PDPK1 SPDYE12 ACE CIT SLC2A3 SPDYE11 LATS1 AP1B1 SPDYE15 SPDYE8 HTT SPDYE14	9.59e-04	969	111	14	GO:0019900
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	SLC2A3 SLC5A6 SLC22A2	1.04e-03	36	111	3	GO:0090482
GeneOntologyMolecularFunction	active transmembrane transporter activity	TMEM241 ATP13A1 SLC5A9 SLC44A5 SLC5A6 SLC22A2 ATP6V1C2 ATP1A3 SLC26A11	1.38e-03	477	111	9	GO:0022804
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	CACNA1B HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 RHCE RHD ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11 HTT	3.13e-07	1017	99	19	GO:0098660
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	CACNA1B HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 RHCE RHD ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3 HTT	3.54e-07	922	99	18	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transport	CACNA1B LPAR3 HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 ACE ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 SLC22A2 KCNJ13 ATP6V1C2 ATP1A3 HTT	2.16e-06	1157	99	19	GO:0006812
GeneOntologyBiologicalProcess	metal ion transport	CACNA1B LPAR3 HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 ACE ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP1A3 HTT	5.09e-06	1000	99	17	GO:0030001
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA1B LPAR3 HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 ACE ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 SLC22A2 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11 HTT	6.95e-06	1374	99	20	GO:0006811
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	CACNA1B HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3 HTT	1.01e-05	942	99	16	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CACNA1B HECW1 ATP13A1 PDPK1 SLC5A9 STEAP2 ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3 SLC5A6 KCNJ13 ATP6V1C2 ATP1A3 SLC26A11 HTT	2.10e-05	1115	99	17	GO:0034220
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	LPAR3 ADGRG3 OR8D2 GPR34 WBP1L GPR52 OR8U3 ACE F2RL1 ITPR1 OR1L8 OR52A4P LRP1 SYP P2RY14 TAAR1 C5 BAIAP3 HTT	3.10e-05	1395	99	19	GO:0007186
GeneOntologyBiologicalProcess	endomembrane system organization	CACNA1B DNAJC13 SMPD4 CIT HPS3 MFSD14A AP1B1 TRAM1 LPCAT3 SYP BAIAP3 HTT	9.00e-05	672	99	12	GO:0010256
GeneOntologyBiologicalProcess	import across plasma membrane	CACNA1B STEAP2 SLC2A3 SLC5A6 SLC22A2 KCNJ13 ATP1A3	1.22e-04	230	99	7	GO:0098739
Domain	Ion_trans_dom	CACNA1B ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3	3.39e-05	114	100	6	IPR005821
Domain	Ion_trans	CACNA1B ITPR1 ITPR2 KCNA7 CATSPER2 KCNC3	3.39e-05	114	100	6	PF00520
Domain	InsP3_rcpt-bd	ITPR1 ITPR2	8.48e-05	3	100	2	IPR000493
Domain	Channel_four-helix_dom	CACNA1B KCNA7 CATSPER2 KCNC3	2.46e-04	57	100	4	IPR027359
Domain	-	CACNA1B KCNA7 CATSPER2 KCNC3	2.46e-04	57	100	4	1.20.120.350
Domain	SUGAR_TRANSPORT_1	SLC2A3 MFSD14A SLC22A2	2.78e-04	24	100	3	PS00216
Domain	Ammonium_transpt	RHCE RHD	2.81e-04	5	100	2	IPR001905
Domain	Ammonium_transp	RHCE RHD	2.81e-04	5	100	2	PF00909
Domain	NH4_transpt_AmtB-like_dom	RHCE RHD	2.81e-04	5	100	2	IPR024041
Domain	RhesusRHD	RHCE RHD	2.81e-04	5	100	2	IPR002229
Domain	RIH_assoc	ITPR1 ITPR2	4.20e-04	6	100	2	PF08454
Domain	RIH_assoc-dom	ITPR1 ITPR2	4.20e-04	6	100	2	IPR013662
Domain	RIH_dom	ITPR1 ITPR2	4.20e-04	6	100	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR1 ITPR2	4.20e-04	6	100	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR1 ITPR2	4.20e-04	6	100	2	IPR015925
Domain	-	ITPR1 ITPR2	4.20e-04	6	100	2	1.25.10.30
Domain	RYDR_ITPR	ITPR1 ITPR2	4.20e-04	6	100	2	PF01365
Domain	Ins145_P3_rec	ITPR1 ITPR2	4.20e-04	6	100	2	PF08709
Domain	-	RHCE RHD	5.86e-04	7	100	2	1.10.3430.10
Domain	Ammonium/urea_transptr	RHCE RHD	5.86e-04	7	100	2	IPR029020
Domain	Sugar_transporter_CS	SLC2A3 MFSD14A SLC22A2	6.60e-04	32	100	3	IPR005829
Domain	Na/solute_symporter_CS	SLC5A9 SLC5A6	7.78e-04	8	100	2	IPR018212
Domain	MIR	ITPR1 ITPR2	1.24e-03	10	100	2	PS50919
Domain	MIR	ITPR1 ITPR2	1.24e-03	10	100	2	PF02815
Domain	MIR	ITPR1 ITPR2	1.24e-03	10	100	2	SM00472
Domain	MIR_motif	ITPR1 ITPR2	1.24e-03	10	100	2	IPR016093
Domain	NA_SOLUT_SYMP_1	SLC5A9 SLC5A6	1.51e-03	11	100	2	PS00456
Domain	Cyclin-like	RBL2 CASD1 CCNB3	1.57e-03	43	100	3	IPR013763
Domain	NA_SOLUT_SYMP_2	SLC5A9 SLC5A6	1.81e-03	12	100	2	PS00457
Domain	SSF	SLC5A9 SLC5A6	1.81e-03	12	100	2	PF00474
Domain	Na/solute_symporter	SLC5A9 SLC5A6	1.81e-03	12	100	2	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A9 SLC5A6	1.81e-03	12	100	2	PS50283
Domain	GPCR_Rhodpsn_7TM	LPAR3 OR8D2 GPR34 GPR52 OR8U3 F2RL1 OR1L8 OR52A4P P2RY14 TAAR1	3.14e-03	670	100	10	IPR017452
Domain	7tm_1	LPAR3 OR8D2 GPR34 GPR52 OR8U3 F2RL1 OR1L8 OR52A4P P2RY14 TAAR1	3.38e-03	677	100	10	PF00001
Domain	SUGAR_TRANSPORT_2	SLC2A3 SLC22A2	3.66e-03	17	100	2	PS00217
Domain	G_PROTEIN_RECEP_F1_1	LPAR3 OR8D2 GPR34 GPR52 OR8U3 F2RL1 OR1L8 OR52A4P P2RY14 TAAR1	3.67e-03	685	100	10	PS00237
Domain	G_PROTEIN_RECEP_F1_2	LPAR3 OR8D2 GPR34 GPR52 OR8U3 F2RL1 OR1L8 OR52A4P P2RY14 TAAR1	3.90e-03	691	100	10	PS50262
Domain	GPCR_Rhodpsn	LPAR3 OR8D2 GPR34 GPR52 OR8U3 F2RL1 OR1L8 OR52A4P P2RY14 TAAR1	3.94e-03	692	100	10	IPR000276
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	ATP13A1 TECR F2RL1 STT3A ITPR2 SLC44A5 CLK3 TRAM1 DERL3 HTT	6.31e-08	296	116	10	34186245
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF12 NBPF20 NBPF19 NBPF10	6.73e-07	21	116	4	16079250
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CHST14 DCBLD1 NBPF26 EXTL3 LBR STT3A ITPR1 ITPR2 FANCA XYLT2 TRAM1 LPCAT3 TMEM245 SLC5A6 LRP1 HTT	2.52e-06	1201	116	16	35696571
Pubmed	Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.	RHCE RHD	1.10e-05	2	116	2	8188244
Pubmed	DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule.	RHCE RHD	1.10e-05	2	116	2	17900276
Pubmed	RHD and RHCE molecular analysis in weak D blood donors and in patients with Rh antibodies against their own corresponding Rh antigen.	RHCE RHD	1.10e-05	2	116	2	32697929
Pubmed	N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease.	CACNA1B HTT	1.10e-05	2	116	2	28391067
Pubmed	GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation.	ADGRG3 F2RL1	1.10e-05	2	116	2	36302784
Pubmed	Review: the molecular basis of the Rh blood group phenotypes.	RHCE RHD	1.10e-05	2	116	2	15373666
Pubmed	Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations.	RHCE RHD	1.10e-05	2	116	2	26579938
Pubmed	Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion.	RHCE RHD	1.10e-05	2	116	2	34968422
Pubmed	Regarding the size of Rh proteins.	RHCE RHD	1.10e-05	2	116	2	1898705
Pubmed	PCR screening for common weak D types shows different distributions in three Central European populations.	RHCE RHD	1.10e-05	2	116	2	11161244
Pubmed	RH diversity in Mali: characterization of a new haplotype RHDDIVa/RHCEceTI(D2).	RHCE RHD	1.10e-05	2	116	2	25857637
Pubmed	Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.	ITPR1 ITPR2	1.10e-05	2	116	2	15201137
Pubmed	The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCEce818T alleles that are often in cis to RHDDOL.	RHCE RHD	1.10e-05	2	116	2	22738288
Pubmed	Multiple Rh messenger RNA isoforms are produced by alternative splicing.	RHCE RHD	1.10e-05	2	116	2	1379850
Pubmed	Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.	ITPR1 ITPR2	1.10e-05	2	116	2	23582047
Pubmed	Characterization of the mouse Rh blood group gene.	RHCE RHD	1.10e-05	2	116	2	10329015
Pubmed	RHCEceMO is frequently in cis to RHDDAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance.	RHCE RHD	1.10e-05	2	116	2	23772606
Pubmed	Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.	RHCE RHD	1.10e-05	2	116	2	3135863
Pubmed	Sequences and evolution of mammalian RH gene transcripts and proteins.	RHCE RHD	1.10e-05	2	116	2	9811965
Pubmed	Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.	RHCE RHD	1.10e-05	2	116	2	12393640
Pubmed	Molecular genetic basis of the human Rhesus blood group system.	RHCE RHD	1.10e-05	2	116	2	8220426
Pubmed	Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.	ITPR1 ITPR2	1.10e-05	2	116	2	19120126
Pubmed	Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.	RHCE RHD	1.10e-05	2	116	2	7916743
Pubmed	RHDDOL1 and RHDDOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent.	RHCE RHD	1.10e-05	2	116	2	22690701
Pubmed	No Distinction of Orthology/Paralogy between Human and Chimpanzee Rh Blood Group Genes.	RHCE RHD	1.10e-05	2	116	2	26872772
Pubmed	RHCEceTI encodes partial c and partial e and is often in cis to RHDDIVa.	RHCE RHD	1.10e-05	2	116	2	22804620
Pubmed	Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.	RHCE RHD	1.10e-05	2	116	2	7789951
Pubmed	E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.	RHCE RHD	1.10e-05	2	116	2	11724987
Pubmed	A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.	GPR52 HTT	1.10e-05	2	116	2	25738228
Pubmed	The Rh blood group system: a review.	RHCE RHD	1.10e-05	2	116	2	10627438
Pubmed	Polymorphisms in the promoter regions of RHD and RHCE genes in the Chinese Han population.	RHCE RHD	1.10e-05	2	116	2	37823181
Pubmed	Sequence diversity of the Rh blood group system in Basques.	RHCE RHD	1.10e-05	2	116	2	30089826
Pubmed	Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia.	RHCE RHD	1.10e-05	2	116	2	29193104
Pubmed	An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.	ITPR1 ITPR2	1.10e-05	2	116	2	18708078
Pubmed	RHCE variants inherited with altered RHD alleles in Brazilian blood donors.	RHCE RHD	1.10e-05	2	116	2	27111588
Pubmed	Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity.	RHCE RHD	1.10e-05	2	116	2	8822955
Pubmed	Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene.	RHCE RHD	1.10e-05	2	116	2	8808597
Pubmed	Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese.	RHCE RHD	1.10e-05	2	116	2	12201845
Pubmed	Variant RH alleles and Rh immunisation in patients with sickle cell disease.	RHCE RHD	1.10e-05	2	116	2	24960646
Pubmed	Comprehensive phenotypic and molecular investigation of RhD and RhCE variants in Moroccan blood donors.	RHCE RHD	1.10e-05	2	116	2	30418133
Pubmed	A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes.	RHCE RHD	1.10e-05	2	116	2	23550903
Pubmed	Molecular cloning and primary structure of the human blood group RhD polypeptide.	RHCE RHD	1.10e-05	2	116	2	1438298
Pubmed	Molecular background of D(C)(e) haplotypes within the white population.	RHCE RHD	1.10e-05	2	116	2	12084172
Pubmed	The analysis of nucleotide substitutions, gaps, and recombination events between RHD and RHCE genes through complete sequencing.	RHCE RHD	1.10e-05	2	116	2	10924335
Pubmed	A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.	RHCE RHD	1.10e-05	2	116	2	12857961
Pubmed	Specific amino acid substitutions cause distinct expression of JAL (RH48) and JAHK (RH53) antigens in RhCE and not in RhD.	RHCE RHD	1.10e-05	2	116	2	20233350
Pubmed	A recombination hot spot in the Rh genes revealed by analysis of unrelated donors with the rare D-- phenotype.	RHCE RHD	1.10e-05	2	116	2	8900235
Pubmed	RHDweak partial 4.0 is associated with an altered RHCEce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population.	RHCE RHD	1.10e-05	2	116	2	23742316
Pubmed	A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa.	RHCE RHD	1.10e-05	2	116	2	24033223
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	UBE4B ITPR1 FANCA VPS52 HTT	2.67e-05	104	116	5	31240132
Pubmed	Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.	ITPR1 ITPR2	3.30e-05	3	116	2	10874040
Pubmed	Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.	ITPR1 ITPR2	3.30e-05	3	116	2	20395455
Pubmed	De novo point mutations in patients diagnosed with ataxic cerebral palsy.	ITPR1 KCNC3	3.30e-05	3	116	2	25981959
Pubmed	Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.	ITPR1 ITPR2	3.30e-05	3	116	2	17437169
Pubmed	Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.	ITPR1 ITPR2	3.30e-05	3	116	2	18547250
Pubmed	Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.	ITPR1 ITPR2	3.30e-05	3	116	2	36350267
Pubmed	Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.	ITPR1 ITPR2	3.30e-05	3	116	2	32320395
Pubmed	The versatility and universality of calcium signalling.	ITPR1 ITPR2	3.30e-05	3	116	2	11413485
Pubmed	Evolutionary history of the Rh blood group-related genes in vertebrates.	RHCE RHD	3.30e-05	3	116	2	10970100
Pubmed	Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	3.30e-05	3	116	2	26009177
Pubmed	Conserved evolution of the Rh50 gene compared to its homologous Rh blood group gene.	RHCE RHD	3.30e-05	3	116	2	9705835
Pubmed	Receptor-activated single channels in intact human platelets.	ITPR1 ITPR2	3.30e-05	3	116	2	1693919
Pubmed	Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.	ITPR1 ITPR2	3.30e-05	3	116	2	23955339
Pubmed	Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.	ITPR1 ITPR2	3.30e-05	3	116	2	31979185
Pubmed	Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.	ITPR1 ITPR2	3.30e-05	3	116	2	24904548
Pubmed	The members of the RH gene family (RH50 and RH30) followed different evolutionary pathways.	RHCE RHD	3.30e-05	3	116	2	9929383
Pubmed	Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.	ITPR1 ITPR2	3.30e-05	3	116	2	9858485
Pubmed	Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane.	RHCE RHD	3.30e-05	3	116	2	3146980
Pubmed	Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.	ITPR1 ITPR2	3.30e-05	3	116	2	9808793
Pubmed	Generation and characterisation of Rhd and Rhag null mice.	RHCE RHD	3.30e-05	3	116	2	19807729
Pubmed	Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.	ITPR1 ITPR2	3.30e-05	3	116	2	18194433
Pubmed	IP3 receptors regulate vascular smooth muscle contractility and hypertension.	ITPR1 ITPR2	3.30e-05	3	116	2	27777977
Pubmed	Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures.	RHCE RHD	3.30e-05	3	116	2	16584906
Pubmed	Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.	ITPR1 ITPR2	3.30e-05	3	116	2	17581770
Pubmed	Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.	ITPR1 ITPR2	3.30e-05	3	116	2	18241669
Pubmed	Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.	ITPR1 ITPR2	3.30e-05	3	116	2	19068129
Pubmed	Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	3.30e-05	3	116	2	17327232
Pubmed	Type 1 inositol (1,4,5)-trisphosphate receptor activates ryanodine receptor 1 to mediate calcium spark signaling in adult mammalian skeletal muscle.	ITPR1 ITPR2	3.30e-05	3	116	2	23223241
Pubmed	Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.	ITPR1 ITPR2	3.30e-05	3	116	2	16014380
Pubmed	Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.	ITPR1 ITPR2	3.30e-05	3	116	2	17890015
Pubmed	Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.	ITPR1 ITPR2	3.30e-05	3	116	2	23983250
Pubmed	Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.	ITPR1 ITPR2	3.30e-05	3	116	2	20427533
Pubmed	Association of PS1 1/2, ACE I/D, and LRP C/T polymorphisms with Alzheimer's disease in the Chinese population: a meta-analysis of case-control studies.	ACE LRP1	3.30e-05	3	116	2	25730041
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	CDS1 UPF3A XYLT2 USP38 ATP6V1C2 HTT	3.93e-05	186	116	6	33637726
Pubmed	Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.	ITPR1 ITPR2	6.59e-05	4	116	2	25215520
Pubmed	The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.	SYP ATP1A3	6.59e-05	4	116	2	12458206
Pubmed	Entire sequence of a mouse chromosomal segment containing the gene Rhced and a comparative analysis of the homologous human sequence.	RHCE RHD	6.59e-05	4	116	2	12459264
Pubmed	The structural evolution of a P2Y-like G-protein-coupled receptor.	GPR34 P2RY14	6.59e-05	4	116	2	12835326
Pubmed	The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation.	NAA15 HTT	6.59e-05	4	116	2	20154145
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	ITPR1 ITPR2	6.59e-05	4	116	2	19120137
Pubmed	Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR2	6.59e-05	4	116	2	11163362
Pubmed	Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.	ITPR1 ITPR2	6.59e-05	4	116	2	21424589
Pubmed	Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.	ITPR1 ITPR2	6.59e-05	4	116	2	21818117
Pubmed	Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.	ITPR1 ITPR2	6.59e-05	4	116	2	28615414
Pubmed	Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.	ITPR1 ITPR2	6.59e-05	4	116	2	10828023
Pubmed	Interactions of Rabconnectin-3 with Cav2 calcium channels.	CACNA1B DMXL2	6.59e-05	4	116	2	31253182
Pubmed	Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington's disease mice.	SLC2A3 HTT	6.59e-05	4	116	2	25526803
Interaction	VSTM1 interactions	ADGRG3 ATP13A1 STEAP2 GJB5 PLPP2	9.82e-06	56	103	5	int:VSTM1
Interaction	GCGR interactions	DMXL2 CDS1 CIT LPCAT3 TMEM68 ATP1A3	2.14e-05	110	103	6	int:GCGR
Interaction	CD63 interactions	CDS1 SLC5A9 F2RL1 LPCAT3 SLC22A2 TMEM68	2.63e-05	114	103	6	int:CD63
Interaction	KRTCAP2 interactions	CDS1 STT3A SLC44A5 LPCAT3 SLC22A2	3.37e-05	72	103	5	int:KRTCAP2
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE17 SPDYE10 SPDYE9 CASTOR2 SPDYE12 SPDYE11 SPDYE13 SPDYE15 SPDYE8 SPDYE14	2.42e-09	271	118	10	chr7q11
Cytoband	7q11.23	SPDYE10 SPDYE9 CASTOR2 SPDYE8 SPDYE14	5.50e-06	97	118	5	7q11.23
GeneFamily	Neuroblastoma breakpoint family	NBPF12 NBPF26 NBPF20 NBPF19 NBPF10	5.03e-08	23	81	5	662
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR2	5.93e-05	3	81	2	297
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1 HECW1 BAIAP3	5.56e-04	36	81	3	823
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE9 SPDYE8	1.27e-03	12	81	2	756
Coexpression	GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN	PALD1 GPR34 HPS3 FANCA PLPP2 DERL3 ATP1A3	6.89e-06	167	110	7	M7621
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDHR2 SLC5A9 NBPF26 STEAP2 ITPR2 NBPF19 NBPF10 C5	4.01e-08	195	114	8	e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell	BAL-Mild-cDC_3\|Mild / Compartment, Disease Groups and Clusters	PALD1 RPGRIP1 GPR34 CDHR2 UPF3A ITPR2 DERL3	3.60e-07	176	114	7	f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PAQR9 CACNA1B HECW1 FCHO1 SYP ATP1A3	9.57e-06	190	114	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	HECW1 CASTOR2 FCHO1 SLC2A3 SYP ATP1A3	1.05e-05	193	114	6	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B HECW1 SLC44A5 SYP ANKRD36 ATP1A3	1.21e-05	198	114	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B HECW1 ITPR1 SLC44A5 SYP ATP1A3	1.21e-05	198	114	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 RHCE KLHL5 DERL3 P2RY14	3.36e-05	143	114	5	5a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 RHCE KLHL5 DERL3 P2RY14	3.59e-05	145	114	5	997bd540c43725a85ca97e4b79ebe0d336860287
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDS1 KCNC3 KCNJ13 ATP6V1C2 C5	4.36e-05	151	114	5	fce04bce66411c21cd5d4d41375f26f1f50f3348
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHST14 SLC5A9 CIT SLC2A3 TAAR1	4.79e-05	154	114	5	2d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHST14 SLC5A9 CIT SLC2A3 TAAR1	4.79e-05	154	114	5	0dec222101530f1727184dbb7c03969d3884f111
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPAR3 GPR34 ACE ANKRD36 ATP1A3	5.41e-05	158	114	5	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPAR3 GPR34 ACE ANKRD36 ATP1A3	5.74e-05	160	114	5	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	PND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	EFCAB11 GPR34 CIT XYLT2 AP1B1	5.74e-05	160	114	5	4480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	ADGRG3 CDHR2 CMTM2 SLC2A3 P2RY14	5.91e-05	161	114	5	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR9 F2RL1 RHD DERL3 LRP1	5.91e-05	161	114	5	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 SLC2A3 ITPR2 UTP25 BAIAP3	6.45e-05	164	114	5	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 SLC2A3 ITPR2 UTP25 BAIAP3	6.45e-05	164	114	5	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 SLC2A3 ITPR2 UTP25 BAIAP3	6.45e-05	164	114	5	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR9 HECW1 F2RL1 RHD DERL3	6.64e-05	165	114	5	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	Influenza_Severe-pDC\|World / Disease group and Cell class	PALD1 TMEM241 NBPF20 DERL3 P2RY14	6.83e-05	166	114	5	bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCell	Influenza_Severe-pDC\|Influenza_Severe / Disease group and Cell class	PALD1 TMEM241 NBPF20 DERL3 P2RY14	6.83e-05	166	114	5	b43a5cd4d28118cf6e56a435deb8ea9435608a90
ToppCell	droplet-Lung-nan-3m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 GPR34 CIT SLC2A3 P2RY14	7.43e-05	169	114	5	da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCell	droplet-Lung-nan-3m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 GPR34 CIT SLC2A3 P2RY14	7.43e-05	169	114	5	a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDS1 KCNC3 KCNJ13 ATP6V1C2 C5	7.43e-05	169	114	5	53e863de064d44e1d36e21fb3dbba37ae020f6e9
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR34 ACE ZNF490 BAIAP3 DISP1	7.64e-05	170	114	5	a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell	390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPR34 ACE ZNF490 BAIAP3 DISP1	7.64e-05	170	114	5	b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DCDC2C KCNC3 KCNJ13 ATP6V1C2 C5	7.64e-05	170	114	5	d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCell	droplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGRG3 GPR34 CIT SLC2A3 P2RY14	8.30e-05	173	114	5	120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCell	droplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGRG3 GPR34 CIT SLC2A3 P2RY14	8.30e-05	173	114	5	b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCell	P03-Epithelial-epithelial_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KCNC3 TMEM245 KCNJ13 ATP6V1C2 C5	8.53e-05	174	114	5	23c7fdfc73170cfc5cdee5bb7fbee0c8bbbbca07
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCA KY USP38 SYP TAAR1	8.53e-05	174	114	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KCNC3 TMEM245 KCNJ13 ATP6V1C2 C5	8.76e-05	175	114	5	a6d9ca35d3c4b4e3889d0a69b514f63ae630da6b
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDS1 GPR52 KY RTL1 TAAR1	9.49e-05	178	114	5	fcbbcc44271515de1969b4732b6441c012693d5f
Disease	Anemia, Hemolytic, Congenital	RHCE RHD	1.21e-05	2	103	2	C0002881
Disease	Anoxic Encephalopathy	ITPR1 ITPR2	1.21e-05	2	103	2	C0003132
Disease	Brain Hypoxia	ITPR1 ITPR2	1.21e-05	2	103	2	C1527348
Disease	Anoxia of brain	ITPR1 ITPR2	1.21e-05	2	103	2	C0995195
Disease	Hypoxic Brain Damage	ITPR1 ITPR2	1.21e-05	2	103	2	C1140716
Disease	Rh Deficiency Syndrome	RHCE RHD	3.61e-05	3	103	2	C0272052
Disease	Rh-Null, Regulator Type	RHCE RHD	3.61e-05	3	103	2	C1849387
Disease	Failure to Thrive	AP1B1 SLC5A6	1.79e-04	6	103	2	C0015544
Disease	Developmental regression	CACNA1B SLC5A6	2.51e-04	7	103	2	C1836830
Disease	epilepsy (implicated_via_orthology)	CACNA1B CIT KCNA7 LRP1 ATP1A3	2.74e-04	163	103	5	DOID:1826 (implicated_via_orthology)
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR2	7.78e-04	12	103	2	DOID:1441 (implicated_via_orthology)
Disease	Intellectual Disability	CACNA1B NAA15 FBXL3 STT3A AP1B1 SLC5A6 HTT	9.93e-04	447	103	7	C3714756
Disease	Global developmental delay	CACNA1B STT3A AP1B1 SLC5A6	1.24e-03	133	103	4	C0557874
Disease	Leber congenital amaurosis	RPGRIP1 KCNJ13	1.40e-03	16	103	2	cv:C0339527
Disease	pneumonia (is_implicated_in)	ACE C5	1.40e-03	16	103	2	DOID:552 (is_implicated_in)
Disease	renal fibrosis (implicated_via_orthology)	GPR52 ACE	1.59e-03	17	103	2	DOID:0050855 (implicated_via_orthology)
Disease	Huntington Disease	SLC2A3 HTT	1.59e-03	17	103	2	C0020179
Disease	Leber Congenital Amaurosis	RPGRIP1 KCNJ13	2.66e-03	22	103	2	C0339527

Protein segments in the cluster

Peptide	Gene	Start	Entry
FLEALEFYYPEHFTL	CARD10	96	Q9BWT7
RYHRFISFALYLAGF	CDS1	181	Q92903
YTRSPRQDLEYHVFF	CATSPER2	266	Q96P56
PYIRYFVSFVLQFQF	ACE	526	P12821
KTRTLHPVYDELFYF	BAIAP3	1071	O94812
QFFVHFLSLVYLYRE	ATP13A1	1061	Q9HD20
TICFVPYHAFRFIYI	GPR34	276	Q9UPC5
AYYISTFKFDHALVP	CASTOR2	296	A6NHX0
AYTFYPSRLFRAHQF	APCDD1L	76	Q8NCL9
ILFEYYRGFTLFQTH	CLK3	511	P49761
FHLYLLAVRVFNTYF	ADGRG3	361	Q86Y34
LAVRVFNTYFGHYFL	ADGRG3	366	Q86Y34
DVFYFSTLYPLHILF	AP1B1	821	Q10567
ITDFFGRTALHYAVY	ANKRD36	126	A6QL64
VAFSFYNYLRTHPLL	DMXL2	1836	Q8TDJ6
IAVGHIYYFLEDVFP	DERL3	176	Q96Q80
ELSIFYVVYFVVFPF	CACNA1B	1391	Q00975
VSYFLYRVVFHFEFF	DISP1	541	Q96F81
AFAYREPYLFVTHFN	CIT	1831	O14578
AVYYKYSHPVFFEVA	CCNB3	1356	Q8WWL7
FFRVVPQFVVFYLIY	UQCRQ	46	O14949
HLARNLIYFGFYSFS	ITPR2	866	Q14571
FIYSFQAFYLVSHPN	LBR	466	Q14739
YYLHEQYPLAFALSF	PALD1	436	Q9ULE6
PFITEIFDVPLYHFY	RBL2	551	Q08999
LPIATAFTEYVHAYF	FCHO1	626	O14526
YPPVYYFLSHLSFID	OR8D2	56	Q9GZM6
HKTLYYDVEPFLFYV	KAT7	431	O95251
VHEFFYSLLLFDLVY	ITPR1	2416	Q14643
PEHAFYEFTFRRFFD	LATS1	1071	O95835
PEFFTVLHANYSAYR	HECW1	961	Q76N89
YNEFYFLTHPALFIE	KY	301	Q8NBH2
IPHIFALTLFEDYVY	LRP1	3231	Q07954
CIPHIYVFFQFYLLA	OR52A4P	246	A6NMU1
SDECPFFIFPLTYYH	KCNJ13	231	O60928
FHFPFYYLLANLAAA	LPAR3	61	Q9UBY5
ISIFLGYPFALFYRH	LPCAT3	46	Q6P1A2
FDYILAADVVYAHPF	METTL21EP	191	A6NDL7
FFLVAFALYVGYTRV	PLPP2	201	O43688
LYAPAAFVVCFTYFH	GPR52	211	Q9Y2T5
FPLHIFVVYSRAYTS	KLHL5	6	Q96PQ7
HPFYFKAARIAIEIY	NAA15	551	Q9BXJ9
PALYGFIFYIFHVEL	MFSD14A	386	Q96MC6
NPFEYYIFFFALSLI	SMPD4	191	Q9NXE4
PTLFVHFYRRYFWLV	PAQR9	271	Q6ZVX9
PFVYYFVSHDFRDHA	F2RL1	341	P55085
ARARPHSYLDAYFVF	CDHR2	1091	Q9BYE9
NIFFFLVLLSYERYH	HTT	1496	P42858
YFFDRHRPSFDAVLY	KCNA7	56	Q96RP8
LYLFDYTDTFLPFIH	BFAR	286	Q9NZS9
FYTHSSFFIPIIYIL	CASD1	396	Q96PB1
HFYVAVGLETFKYFP	DCDC2C	201	A8MYV0
DPFFRYEIPATHLYF	FBXL3	301	Q9UKT7
LFVILVFFPLIAHYY	EXTL3	36	O43909
VFFPLIAHYYLTTLD	EXTL3	41	O43909
ASIFRRPYYVSHFLP	FANCA	571	O15360
GFLSPATFTVYEYHR	C5	1486	P01031
YEFFNELYHRFLLTP	DNAJC13	851	O75165
VQIYDDYFIHYFAPR	ITIH6	261	Q6UXX5
AFPYSFLIFVYDEIR	ATP1A3	981	P13637
PSAAHYLGAYVFIIF	SLC2A3	421	P11169
FLYTFRYFCTPHDFL	KNDC1	1276	Q76NI1
QYIPTFHVYNLFVFL	SLC44A5	451	Q8NCS7
YPFARHQSAEFTISY	DCBLD1	506	Q8N8Z6
VDIAFLYVFHSFYPK	GJB5	141	O95377
VRHIFTAFDTYYRGF	EFCAB11	96	Q9BUY7
IYLDFFYSALVEFPA	SLC22A2	376	O15244
VFPYDLYHAERAIAF	HELB	351	Q8NG08
FDRYVAVCDPFHYVT	OR1L8	121	Q8NGR8
NFIEFVFPYRHFVER	RTL1	811	A6NKG5
FEYPFRLHQVYFDAP	SYP	71	P08247
IFYELPTYPHFYSEI	UTP25	686	Q68CQ4
QDYFPYVYFHIDLSL	ATP6V1C2	411	Q8NEY4
VEFLTSVHLYYLFPS	DROSHA	976	Q9NRR4
SPYAVYRFFTFSDHD	RPGRIP1	821	Q96KN7
SLFCFFSLPHVGYLY	HPS3	341	Q969F9
LPDSFQHYRSVFYSF	NBPF10	3746	Q6P3W6
FELPDSFQHYRSVFY	NBPF12	1406	Q5TAG4
YFELPDSFQHYRSVF	NBPF19	3791	A0A087WUL8
FELPDSFQHYRSVFY	NBPF20	5156	P0DPF2
FELPDSFQHYRSVFY	NBPF26	851	B4DH59
IFIPVFYRLHLTSAY	SLC5A6	116	Q9Y289
FKTFFVHTPNRTYYL	PDPK1	511	O15530
YFEFFAADLSLYPHL	UPF3A	96	Q9H1J1
HEFDPYFNYRTTRFL	STT3A	46	P46977
NIFYFLYEETRSHIP	SPDYE10	181	P0DUX0
NIFYFLYEETRSHIP	SPDYE11	181	P0DTA3
NIFYFLYEETRSHIP	SPDYE8	181	P0DUD1
RPAVLKDFHYLYFAI	SLC5A9	521	Q2M3M2
FFLYSFVRDVIHPYA	STEAP2	226	Q8NFT2
AVPYIYSFLVALFHT	OR8U3	146	Q8NH85
FSIVFVFFVCFVPYH	P2RY14	236	Q15391
YQHLLSYSFPDFFAL	ARMCX1	321	Q9P291
YRLQHYFKFLFVREP	CHST14	201	Q8NCH0
SFFILLYSFAIHRYI	CMTM2	126	Q8TAZ6
YPFEALFRSQHYALL	VPS52	376	Q8N1B4
RRALAVYPVFLFYFV	YIPF6	211	Q96EC8
IIFYHGAIPIDFYYF	TMEM68	126	Q96MH6
AFIYYQPFLTHERTH	ZNF490	286	Q9ULM2
EAALILLFYFFTHYD	RHD	21	Q02161
EAALILLFYFFTHYD	RHCE	21	P18577
LVSFYTFHEPAYAVL	SLC26A11	111	Q86WA9
NIFYFLYEETRSHIP	SPDYE12	181	P0DUX1
NIFYFLYEETRSHIP	SPDYE13	181	A0A494C0Z2
NIFYFLYEETRSHIP	SPDYE14	181	P0DUD3
NIFYFLYEETRSHIP	SPDYE15	181	P0DUD4
NIFYFLYEETRSHIP	SPDYE17	181	P0DUD2
FYDKFTIRYHISTIF	UBE4B	986	O95155
IYLLFYFRVPFIYGH	TECR	101	Q9NZ01
IFHLSFISIDRYYAV	TAAR1	111	Q96RJ0
EAYARYHRPEFESFF	USP38	66	Q8NB14
VLDFPFLYFYRFHGS	TMEM241	206	Q24JQ0
IFHLLPTYFVDTAIY	TMEM245	781	Q9H330
HYFVEFLFHISRLFY	TRAM1	226	Q15629
NIFYFLYEETRSHIP	SPDYE9	181	A0A494C191
SVPYVFRYFVAELAA	POLR1B	1111	Q9H9Y6
YHLPYAARDLQTFFL	SPAG11A	106	Q6PDA7
EAHNYSALPFYFRFL	WBP1L	86	Q9NX94
FYTYTLLPAESFFHT	XYLT2	426	Q9H1B5
FFDRHPGVFAYVLNY	KCNC3	136	Q14003