Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	immunoglobulin production	IGLV5-39 IGLV1-50 IGLV1-40 IGLV1-36 SASH3 IGKV3D-15 IGKV3D-11 IGKV2D-30 TNFAIP3 IGKV3-20 IGKV3-15 IGKV2-30 IGKV2-24	4.88e-08	241	159	13	GO:0002377
GeneOntologyBiologicalProcess	production of molecular mediator of immune response	IGLV5-39 IGLV1-50 IGLV1-40 IGLV1-36 SASH3 IGKV3D-15 IGKV3D-11 IGKV2D-30 TNFAIP3 IGKV3-20 IGKV3-15 IGKV2-30 IGKV2-24	1.53e-05	403	159	13	GO:0002440
GeneOntologyCellularComponent	immunoglobulin complex	IGLV5-39 IGLV1-50 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV2-30 IGKV2-24	5.96e-08	166	159	11	GO:0019814
GeneOntologyCellularComponent	IgM immunoglobulin complex, circulating	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	2.20e-07	8	159	4	GO:0071754
GeneOntologyCellularComponent	pentameric IgM immunoglobulin complex	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	2.20e-07	8	159	4	GO:0071756
GeneOntologyCellularComponent	monomeric IgA immunoglobulin complex	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	3.94e-07	9	159	4	GO:0071748
GeneOntologyCellularComponent	polymeric IgA immunoglobulin complex	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	6.53e-07	10	159	4	GO:0071749
GeneOntologyCellularComponent	IgA immunoglobulin complex, circulating	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	6.53e-07	10	159	4	GO:0071746
GeneOntologyCellularComponent	secretory IgA immunoglobulin complex	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	6.53e-07	10	159	4	GO:0071751
GeneOntologyCellularComponent	IgA immunoglobulin complex	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	4.12e-06	15	159	4	GO:0071745
GeneOntologyCellularComponent	IgM immunoglobulin complex	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	4.12e-06	15	159	4	GO:0071753
GeneOntologyCellularComponent	immunoglobulin complex, circulating	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	7.10e-06	17	159	4	GO:0042571
GeneOntologyCellularComponent	podocyte foot	THSD7A CASK	1.72e-04	3	159	2	GO:0098846
GeneOntologyCellularComponent	nuclear body	MYC SP100 TOPBP1 JADE1 TRIP12 PALB2 WAC RMI1 SUGP2 GLI3 ELF2 WDFY3 BRD1 HEATR5B SRRM2 ZBTB18	1.47e-03	903	159	16	GO:0016604
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 VAV2 IGKV3-11 IGKV2-30	4.43e-06	86	109	7	M27206
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 VAV2 IGKV3-11 IGKV2-30	4.78e-06	87	109	7	M27205
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	7.31e-06	61	109	6	M27581
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	STAB1 IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.06e-05	98	109	7	M27152
Pathway	REACTOME_FCGR_ACTIVATION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.50e-05	69	109	6	M27108
Pathway	REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.50e-05	69	109	6	M27150
Pathway	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.77e-05	71	109	6	M1078
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.77e-05	71	109	6	M27203
Pathway	REACTOME_COMPLEMENT_CASCADE	IGLV1-40 IGKV2D-30 C7 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.00e-05	115	109	7	M19752
Pathway	REACTOME_PARASITE_INFECTION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 VAV2 IGKV3-11 IGKV2-30	3.18e-05	116	109	7	M29843
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.51e-05	80	109	6	M6121
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	4.04e-05	82	109	6	M27110
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	5.30e-05	86	109	6	M601
Pathway	REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	9.26e-05	95	109	6	M29842
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 VAV2 IGKV3-11 IGKV2-30	1.20e-04	143	109	7	M27107
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 VAV2 IGKV3-11 IGKV2-30	5.97e-04	186	109	7	M27175
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	6.00e-04	134	109	6	M29840
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	6.48e-04	136	109	6	M27207
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MIIP TANC2 KIF26B IRS1 CBL TRIP12 SPICE1 SHKBP1 FSIP2 KCNQ5 CCDC138 OSBPL10 ANKRD17 NR3C2 MTCL1 TNFAIP3 BRD1 CAMSAP1 SRRM2 TNS3 DOP1A OTOG ANKS1A	2.72e-11	861	166	23	36931259
Pubmed	Mouse immunoglobulin chains. Pattern of sequence variation among kappa chains with limited sequence differences.	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	7.45e-09	6	166	4	4691517
Pubmed	Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes.	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	7.45e-09	6	166	4	98179
Pubmed	Mechanisms of antibody diversity: multiple genes encode structurally related mouse kappa variable regions.	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	7.45e-09	6	166	4	99744
Pubmed	The 3' part of the immunoglobulin kappa locus of the mouse.	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	1.73e-08	7	166	4	9603450
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SRRM4 KIF21A PHRF1 TOPBP1 ADGRB3 TRIOBP JADE1 STAB1 TNRC6A FBXO41 ANKRD17 CDK5RAP2 ROBO2 PCNX1 ANKS1A	4.32e-08	529	166	15	14621295
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB CDH26 TUT4 KCNH8 TRIM26 TRIOBP DYNC2I1 ARHGAP39 ATP10A BRWD3 CASK SHKBP1 COL23A1 ARHGAP6 PPARGC1B ASAP2 KCNQ5 SUGP2 NACC2 SETD5 ANKRD17 GREB1 VAV2 DOP1A ANKS1A	4.64e-08	1489	166	25	28611215
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 MAPK8IP1 KIF21A ADGRB2 ADGRB3 TRIOBP ARHGAP39 MAP3K5 SPICE1 CASK IGF2R FBXO41 ANKRD17 CDK5RAP2 MTCL1 WDFY3 CAMSAP1 ANKS1A	9.21e-07	963	166	18	28671696
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MYC TANC2 SP100 TUT4 PHRF1 ZC3H3 BRWD3 TRIM66 SUGP2 SETD5 GLI3 RTL9 TNRC6A ANKRD17 WDFY3 KDM1B BRD1 SRRM2 UNC80	1.79e-06	1116	166	19	31753913
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	TANC2 FLNB FLT1 TRIOBP WAC IGF2R TENM3 ELAPOR1 PCNX1 MTCL1 FEM1A	1.89e-06	371	166	11	15747579
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	FLNB TTLL5 TOPBP1 TRIP12 PALB2 SPICE1 CCDC138 ELF2 KDM1B BRD1 CAMSAP1 USP48 CDCA5 ARHGEF6	2.94e-06	645	166	14	25281560
Pubmed	Recognition of immunoglobulins by Fcgamma receptors.	IGLV1-40 IGLV1-36 IGKV3D-11 IGKV3-20 IGKV2-24	3.38e-06	48	166	5	11955599
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 THSD7A RNPC3 ARHGAP39 ATP10A ARSG WAC TRIM66 ASAP2 ELAPOR1 UNC80 DOP1A	4.89e-06	493	166	12	15368895
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 ADGRB2 IRS1 JADE1 ARSG MAP3K5 PKMYT1 IGF2R KANSL1 SUGP2 SETD5 NEK8 PCNX1 TNFAIP3 WDFY3 CAMSAP1 FEM1A METTL27	6.25e-06	1105	166	18	35748872
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CUX2 THSD7A ADGRB3 TRIOBP STAB1 PCNX1 WDFY3 UNC80	1.36e-05	225	166	8	12168954
Pubmed	IRS1/β-Catenin Axis Is Activated and Induces MYC Expression in Acute Lymphoblastic Leukemia Cells.	MYC IRS1	2.26e-05	2	166	2	27987331
Pubmed	Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia.	FLT1 TNFSF14	2.26e-05	2	166	2	31300808
Pubmed	A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis.	CBL MAP3K5	2.26e-05	2	166	2	19597496
Pubmed	Expression of brain-specific angiogenesis inhibitor 2 (BAI2) in normal and ischemic brain: involvement of BAI2 in the ischemia-induced brain angiogenesis.	ADGRB2 ADGRB3	2.26e-05	2	166	2	12218411
Pubmed	Genome-wide association study identified copy number variants important for appendicular lean mass.	SERHL GIMAP1	2.26e-05	2	166	2	24626161
Pubmed	Protein phosphatase with EF-hand domains 2 (PPEF2) is a potent negative regulator of apoptosis signal regulating kinase-1 (ASK1).	PPEF2 MAP3K5	2.26e-05	2	166	2	20674765
Pubmed	c-Cbl regulates αPix-mediated cell migration and invasion.	CBL ARHGEF6	2.26e-05	2	166	2	25450678
Pubmed	Human immunoglobulin kappa light chain genes of subgroups II and III.	IGKV3-20 IGKV2-30	2.26e-05	2	166	2	2997711
Pubmed	c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPases.	CBL VAV2	2.26e-05	2	166	2	11313921
Pubmed	USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection.	TNFAIP3 USP48	2.26e-05	2	166	2	35913642
Pubmed	Ataxia is the major neuropathological finding in arylsulfatase G-deficient mice: similarities and dissimilarities to Sanfilippo disease (mucopolysaccharidosis type III).	SGSH ARSG	2.26e-05	2	166	2	25452429
Pubmed	NEK8 regulates colorectal cancer progression via phosphorylating MYC.	MYC NEK8	2.26e-05	2	166	2	37596667
Pubmed	A human MAP kinase interactome.	MYC SP100 KIF26B CBL MAP3K5 ASAP2 KANSL1 TNRC6A ANKRD17 TNFAIP3 ZBTB18	2.39e-05	486	166	11	20936779
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLNB USP24 TOPBP1 CBL TRIP12 WAC C18orf21 MTCL1 SRRM2 CDCA5 ARHGEF6	3.27e-05	503	166	11	16964243
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	SRRM4 DUSP15 NEK8 GPR149 MTMR2 PCNX1 SRRM2 UNC80 TNS3 DOP1A	3.70e-05	420	166	10	28065597
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DSC3 TRIOBP ARHGAP39 PPEF2 SPICE1 CASK SHKBP1 MTMR7 AAAS IGF2R CCDC138 TNRC6A MTMR2 CDK5RAP2 SRRM2 TNS3	4.62e-05	1049	166	16	27880917
Pubmed	Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins.	DYNC2I1 CBL CASK AAAS ANKRD17	5.31e-05	84	166	5	34159380
Pubmed	Small molecule Z363 co-regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth.	MYC TRIP12	6.77e-05	3	166	2	36639831
Pubmed	Aberrant ribosome biogenesis activates c-Myc and ASK1 pathways resulting in p53-dependent G1 arrest.	MYC MAP3K5	6.77e-05	3	166	2	21383696
Pubmed	Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1.	MYC TOPBP1	6.77e-05	3	166	2	18923429
Pubmed	SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex.	CBL SHKBP1	6.77e-05	3	166	2	21830225
Pubmed	Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1).	ADGRB2 ADGRB3	6.77e-05	3	166	2	9533023
Pubmed	Expression of brain-specific angiogenesis inhibitor 3 (BAI3) in normal brain and implications for BAI3 in ischemia-induced brain angiogenesis and malignant glioma.	ADGRB2 ADGRB3	6.77e-05	3	166	2	15225653
Pubmed	GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer.	MYC GLI3	6.77e-05	3	166	2	34610962
Pubmed	Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.	CBL VAV2	6.77e-05	3	166	2	20940296
Pubmed	αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.	CBL ARHGEF6	6.77e-05	3	166	2	26177020
Pubmed	Transforming Growth Factor β-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC.	MYC TRIM26	6.77e-05	3	166	2	29203640
Pubmed	The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor.	IRS1 CBL	6.77e-05	3	166	2	10854852
Pubmed	MYC promotes the development of papillary thyroid carcinoma by inhibiting the expression of lncRNA PAX8‑AS1:28.	MYC PAX8	6.77e-05	3	166	2	30720110
Pubmed	Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity.	MAP3K5 TNFAIP3	6.77e-05	3	166	2	33460648
Pubmed	The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1).	FLT1 CBL	6.77e-05	3	166	2	15001553
Pubmed	The interplay between c-Myc oncogene expression and circulating vascular endothelial growth factor (sVEGF), its antagonist receptor, soluble Flt-1 in diffuse large B cell lymphoma (DLBCL): relationship to patient outcome.	MYC FLT1	6.77e-05	3	166	2	15160911
Pubmed	Immunoglobulin genes of different subgroups are interdigitated within the VK locus.	IGKV3D-11 IGKV3-11	6.77e-05	3	166	2	6440122
Pubmed	The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line.	IGKV3D-15 IGKV3D-11 IGKV3-11	6.91e-05	17	166	3	8223863
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIF26B CCDC138 TNRC6A MTCL1 CAMSAP1 TNS3 ANKS1A	6.92e-05	209	166	7	36779422
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	MAPK8IP1 IRS1 VAV2 TNS3 ANKS1A	7.39e-05	90	166	5	16273093
Pubmed	Physicochemical and functional characterization of the C1r subunit of the first complement component.	IGLV1-40 IGLV1-36 IGKV3D-11 IGKV2-24	7.61e-05	47	166	4	814163
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PHRF1 USP24 ARHGAP39 TRIP12 PALB2 SPICE1 KANSL1 SUGP2 ANKRD17 ELF2 SRRM2 ARHGEF6 ANKS1A	9.48e-05	774	166	13	15302935
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLNB KRT85 TRIP12 CASK SHKBP1 IGF2R OSBPL10 ANKRD17 MTCL1 TNFAIP3 KDM1B SRRM2 USP48 FEM1A KRT36	1.02e-04	1005	166	15	19615732
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	THSD7A TTLL5 ARSG PCNX1 WDFY3	1.34e-04	102	166	5	10231032
Pubmed	Ligand-independent activation of vascular endothelial growth factor receptor 1 by low-density lipoprotein.	FLT1 CBL	1.35e-04	4	166	2	17962812
Pubmed	Molecular characterization of the human immunoglobulin V lambda I germline gene repertoire.	IGLV1-50 IGLV1-40	1.35e-04	4	166	2	1495496
Pubmed	The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins.	CBL ARHGEF6	1.35e-04	4	166	2	12935897
Pubmed	Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity.	MYC GREB1	1.35e-04	4	166	2	31930333
Pubmed	Myotubularins, a large disease-associated family of cooperating catalytically active and inactive phosphoinositides phosphatases.	MTMR7 MTMR2	1.35e-04	4	166	2	12925573
Pubmed	Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.	COL6A3 IRS1	1.35e-04	4	166	2	23818951
Pubmed	CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling.	IRS1 CBL	1.35e-04	4	166	2	29729186
Pubmed	PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.	IRS1 PPARGC1B	1.35e-04	4	166	2	30770439
Pubmed	Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses.	MYC TRIP12	1.35e-04	4	166	2	20208519
Pubmed	Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum.	ADGRB2 ADGRB3	1.35e-04	4	166	2	25611509
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLNB THSD7A RNPC3 FAM161B TRIP12 CASK KANSL1 TENM3 TNFAIP3 BRD1 CAMSAP1	1.37e-04	591	166	11	15231748
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	LRRC3C TUT4 TMEM61 OSBPL10 SRRM2 KRT36	1.38e-04	163	166	6	24316575
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	RNPC3 SRRM4 JADE1 WAC UNC80	1.67e-04	107	166	5	11347906
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	TUT4 JADE1 CBL SHKBP1 AAAS CCDC138 TNRC6A HEATR5B	1.68e-04	322	166	8	39098523
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DSC3 TRIOBP CBL CASK IGF2R TENM3 MTMR2 OSBPL10 ROBO2	2.04e-04	421	166	9	36976175
Pubmed	The IGF2 receptor is a USF2-specific target in nontumorigenic mammary epithelial cells but not in breast cancer cells.	MYC IGF2R	2.24e-04	5	166	2	12857727
Pubmed	Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex.	MAPK8IP1 MAP3K5	2.24e-04	5	166	2	17719230
Pubmed	Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.	IGF2R LPA	2.24e-04	5	166	2	21273553
Pubmed	N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain.	FLT1 CBL	2.24e-04	5	166	2	25387128
Pubmed	SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins.	CBL SHKBP1	2.24e-04	5	166	2	11152963
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L5 FOXD4L4	2.24e-04	5	166	2	12234674
Pubmed	Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte.	CBL VAV2	2.24e-04	5	166	2	11262396
Pubmed	The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters.	IGF2R LPA	2.24e-04	5	166	2	8854860
Pubmed	The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal endometriosis.	MYC GREB1	2.24e-04	5	166	2	22884659
Pubmed	A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.	PHRF1 TNFAIP3 ANKS1A	2.87e-04	27	166	3	23740937
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L5 FOXD4L4	3.35e-04	6	166	2	27092474
Pubmed	A genome-wide association study of a coronary artery disease risk variant.	FLT1 CUX2	3.35e-04	6	166	2	23364394
Pubmed	The human VK locus. Characterization of a duplicated region encoding 28 different immunoglobulin genes.	IGKV3-20 IGKV2-24	3.35e-04	6	166	2	3351922
Pubmed	Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling.	CBL VAV2	3.35e-04	6	166	2	16356860
Pubmed	The SAM domains of Anks family proteins are critically involved in modulating the degradation of EphA receptors.	CBL ANKS1A	3.35e-04	6	166	2	20100865
Pubmed	Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance.	IRS1 PPARGC1B	3.35e-04	6	166	2	12565902
Pubmed	Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.	IRS1 CBL	3.35e-04	6	166	2	15581362
Pubmed	Myc represses transcription through recruitment of DNA methyltransferase corepressor.	MYC ZBTB18	3.35e-04	6	166	2	15616584
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	THSD7A TOPBP1 TRIP12 ASAP2 CDK5RAP2	4.13e-04	130	166	5	12421765
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MAPK8IP1 FLNB KIF21A TTLL5 ADGRB3 TRIOBP DYNC2I1 DNAAF9 TRIP12 BRWD3 WAC CASK STAB1 TRIM66 MTMR2 WDFY3	4.60e-04	1285	166	16	35914814
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	SP100 TRIM66 PHF20L1 BRD1	4.67e-04	75	166	4	25593309
Pubmed	Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors.	CBL VAV2	4.68e-04	7	166	2	8621483
Pubmed	CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.	CBL ASAP2	4.68e-04	7	166	2	17255943
Pubmed	Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation.	MAP3K5 TNFAIP3	4.68e-04	7	166	2	20448643
Pubmed	The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.	MAP3K5 TNFAIP3	4.68e-04	7	166	2	29227477
Pubmed	Myosin-reactive autoantibodies in rheumatic carditis and normal fetus.	IGKV3D-15 IGKV3-20	4.68e-04	7	166	2	9614934
Pubmed	IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.	IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15	5.16e-04	77	166	4	15608191
Pubmed	KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints.	IGF2R KDM1B	6.22e-04	8	166	2	19727073
Pubmed	ADP-ribosylation factor-like GTPase 15 enhances insulin-induced AKT phosphorylation in the IR/IRS1/AKT pathway by interacting with ASAP2 and regulating PDPK1 activity.	IRS1 ASAP2	6.22e-04	8	166	2	28322786
Pubmed	Insulin-like growth factor II receptor, transforming growth factor-beta, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis.	IGF2R LPA	6.22e-04	8	166	2	9438420
Interaction	YWHAG interactions	MIIP MYC TANC2 KIF26B KRT85 USP24 IRS1 PPEF2 CBL TRIP12 MAP3K5 SPICE1 SHKBP1 KCNQ5 OSBPL10 ANKRD17 MTCL1 TNFAIP3 BRD1 CAMSAP1 SRRM2 USP48 ARHGEF6 TNS3 DOP1A OTOG ANKS1A	8.41e-07	1248	154	27	int:YWHAG
Interaction	GSK3A interactions	MYC KIF26B KIF21A ARSG SPICE1 DEFA5 SUGP2 GLI3 CCDC138 TNRC6A MTCL1 CAMSAP1 SRRM2 TNS3 ANKS1A	2.85e-06	464	154	15	int:GSK3A
Interaction	PHIP interactions	MYC TUT4 IRS1 BRWD3 SPICE1 TRIM66 GLI3 TNRC6A ANKRD17 SRRM2	2.87e-06	197	154	10	int:PHIP
Interaction	YWHAH interactions	MIIP TANC2 KIF26B IRS1 CBL TRIP12 MAP3K5 SHKBP1 KCNQ5 CCDC138 OSBPL10 ANKRD17 NR3C2 MTCL1 TNFAIP3 BRD1 CAMSAP1 SRRM2 USP48 ARHGEF6 TNS3 DOP1A OTOG ANKS1A	3.33e-06	1102	154	24	int:YWHAH
Interaction	XYLT1 interactions	MYC TUT4 USP24 ANKRD17	1.77e-05	21	154	4	int:XYLT1
Interaction	SFN interactions	MIIP MYC TANC2 KIF26B IRS1 JADE1 CBL TRIP12 MAP3K5 KCNQ5 NEK8 ANKRD17 CAMSAP1 SRRM2 TNS3 DOP1A ANKS1A	2.29e-05	692	154	17	int:SFN
Cytoband	2p12	IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	1.20e-08	117	166	8	2p12
Cytoband	Ensembl 112 genes in cytogenetic band chr2p11	MRPL35 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	9.48e-08	213	166	9	chr2p11
GeneFamily	Immunoglobulin kappa locus at 2p11.2	IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	5.95e-08	83	116	8	351
GeneFamily	PHD finger proteins	SP100 PHRF1 JADE1 TRIM66 PHF20L1 BRD1	2.46e-05	90	116	6	88
GeneFamily	Adhesion G protein-coupled receptors, subfamily B	ADGRB2 ADGRB3	1.22e-04	3	116	2	912
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5	DEFA5 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	8.24e-07	183	152	10	Arv_SC_fibroblast_1000_K5
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#2	DEFA5 IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-11 IGKV2-30 IGKV2-24	3.48e-05	126	152	7	Arv_SC-HD_500_K2
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3	DEFA5 IGLV1-40 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-11 IGKV2-30 IGKV2-24	5.32e-05	183	152	8	Arv_SC-HD_1000_K3
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#3	DEFA5 IGLV1-40 IGKV2D-30 IGKV3-20 IGKV3-11 IGKV2-30 IGKV2-24	6.50e-05	139	152	7	Arv_SC_fibroblast_500_K3
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.73e-12	177	163	12	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.73e-12	177	163	12	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.73e-12	177	163	12	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	3.12e-12	179	163	12	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	3.12e-12	179	163	12	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	3.12e-12	179	163	12	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	healthy_donor-Lymphocytic-Plasma_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	5.57e-12	188	163	12	bd53b0371154cff680226897b61c9809a239d1b6
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgG_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	PKMYT1 ELL2 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.54e-10	152	163	10	a2ba2d95ac9010e1a62db34dcad10d004f8a90cc
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PKMYT1 IGLV1-50 ELL2 IGKV3D-15 IGKV2D-30 CDCA5 IGKV3-20 IGKV3-15 IGKV2-30 IGKV2-24	8.05e-10	171	163	10	13126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCell	Control-Lymphoid-B_Plasma\|Control / Disease state, Lineage and Cell class	IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 USP48 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	8.53e-10	172	163	10	61e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCell	COPD-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGLV1-50 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 USP48 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.01e-09	175	163	10	d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	1.07e-09	176	163	10	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	1.07e-09	176	163	10	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PKMYT1 IGLV1-40 IGLV1-36 IGKV3D-11 IGKV2D-30 CDCA5 IGKV3-20 IGKV3-11 IGKV2-30 IGKV2-24	2.02e-09	188	163	10	6844cebca177fdf38b21a40d606230a033717a3a
ToppCell	5'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ELL2 IGLV1-40 IGKV3D-15 IGKV3D-11 TNFAIP3 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.35e-09	191	163	10	d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.02e-09	196	163	10	026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell	tumor_Lung-B_lymphocytes-Plasma_cells\|tumor_Lung / Location, Cell class and cell subclass	IGLV1-50 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	1.31e-08	169	163	9	b36b7632ce55fc7b6b8b66020563d360b3de6fd7
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNH8 IGLV1-40 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.05e-08	178	163	9	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.61e-08	183	163	9	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.87e-08	185	163	9	6ec009e48e50471c28e914c402f500e56a88f8f2
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.87e-08	185	163	9	f49ad6401b2abd089e30eba245b11b5031ea2318
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.87e-08	185	163	9	08bc817908076734d66f2805cb954141f2cc5a18
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.87e-08	185	163	9	1704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11	3.00e-08	186	163	9	e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGLV1-40 OSBPL10 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.29e-08	188	163	9	c3cae529fdbeb233d2b32bcc3537a8aba26a7dc2
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ELL2 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	3.61e-08	190	163	9	79ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ELL2 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	3.61e-08	190	163	9	18762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	COL6A3 KIF26B ADGRB3 ARHGAP6 KCNT2 TENM3 GLI3 ROBO2 C7	4.93e-08	197	163	9	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	10x5'-Lung-Lymphocytic_B-ABC_aged-B_memory\|Lung / Manually curated celltypes from each tissue	MAPK8IP1 IRS1 DEFA5 IGLV1-40 OSBPL10 IGKV3-15 IGKV3-11 IGKV2-24	1.33e-07	159	163	8	d3202ddc291b8686dbe67690df13c7daffec2199
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIF26B ADGRB3 IRS1 KCNT2 KCNQ5 PXDNL ROBO2 CDRT15P3	1.69e-07	164	163	8	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	Control-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGLV1-36 IGKV3D-11 IGKV2D-30 USP48 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	2.22e-07	170	163	8	fb05f49b7113470995b3c16683c54dc1a660b73a
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.54e-07	173	163	8	7e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGLV1-50 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.03e-07	177	163	8	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV1-50 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.59e-07	181	163	8	e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.90e-07	183	163	8	cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells\|Liver / Manually curated celltypes from each tissue	IGLV1-50 ELL2 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-11 IGKV2-24	4.06e-07	184	163	8	6f70d8f8ab8362d51f8a58735d42223e06566397
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 LINC00473 THSD7A PAX8 GLI3 OSBPL10 VAV2 TNS3	4.59e-07	187	163	8	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 KIF26B ADGRB3 ARHGAP6 GLI3 ROBO2 C7 VAV2	6.07e-07	194	163	8	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	Biopsy_Other_PF-Immune-Plasma_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	IGLV1-50 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	6.31e-07	195	163	8	d0305c6a68c9e361507b04db94f86873085d49b3
ToppCell	Biopsy_IPF-Immune-Plasma_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	IGLV1-50 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	6.56e-07	196	163	8	a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGLV1-50 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	6.56e-07	196	163	8	fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNH8 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	6.81e-07	197	163	8	88b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	6.81e-07	197	163	8	2662138671262b30508c5759038bcdcfe6551696
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGLV1-50 ELL2 IGLV1-40 IGLV1-36 IGKV3D-11 CDCA5 IGKV3-20 IGKV3-11	6.81e-07	197	163	8	fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KCNH8 IGLV1-36 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	6.81e-07	197	163	8	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	COL6A3 KIF26B ADGRB3 ARHGAP6 TENM3 GLI3 ROBO2 C7	7.08e-07	198	163	8	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 ADGRB3 ARHGAP6 KCNT2 TENM3 GLI3 ROBO2 C7	7.08e-07	198	163	8	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Control-Control-Lymphocyte-B-Plasmablast\|Control / Disease, condition lineage and cell class	PKMYT1 ELL2 IGLV1-40 OSBPL10 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	7.35e-07	199	163	8	c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	COL6A3 ADGRB3 ARHGAP6 KCNT2 TENM3 GLI3 ROBO2 C7	7.35e-07	199	163	8	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 SLC1A6 ARHGAP6 SPACA4 NR3C2 MTCL1 VAV2	1.43e-06	151	163	7	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	PALB2 COL23A1 ARHGAP6 ELAPOR1 ARHGEF6 TNS3 DOP1A	1.86e-06	157	163	7	2c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell	3'_v3-Lung-Lymphocytic_B_plasma-Plasma_cells\|Lung / Manually curated celltypes from each tissue	CBY3 IGLV1-36 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	2.48e-06	164	163	7	3b6a32ba53d05f6818fe950ac426f489383b645a
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNH8 TMEM61 SRRM4 MTMR7 ELAPOR1 GREB1 UNC80	2.80e-06	167	163	7	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	367C-Lymphocytic-Plasma_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGLV1-50 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	2.80e-06	167	163	7	f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell	367C-Lymphocytic-Plasma_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGLV1-50 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	2.80e-06	167	163	7	5e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYC DSC3 TNFSF14 MAP3K5 FOXD4L5 KCNT2 C7	2.92e-06	168	163	7	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	wk_08-11-Hematologic_Lymphocytic-B\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SASH3 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-15 IGKV3-11 IGKV2-30	3.41e-06	172	163	7	d1ab8f493b70ec995281f9fb0991f1d3aa7b928f
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGLV1-40 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30 IGKV2-24	3.96e-06	176	163	7	50e207403d48ce1b55a78897adb5519a2430a626
ToppCell	tumor_Lung-B_lymphocytes-Plasma_cells\|B_lymphocytes / Location, Cell class and cell subclass	IGLV1-50 IGLV1-36 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	3.96e-06	176	163	7	683022c3400e951b26c2b49394dfd3cc415276fe
ToppCell	VE-plasma\|VE / Condition, Cell_class and T cell subcluster	ELL2 IGKV3D-15 IGKV2D-30 IGKV3-20 IGKV3-11 IGKV2-30 IGKV2-24	4.11e-06	177	163	7	0c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell	COPD-Lymphoid-B_Plasma\|COPD / Disease state, Lineage and Cell class	IGLV1-50 IGKV3D-11 IGKV2D-30 USP48 IGKV3-20 IGKV3-15 IGKV2-30	4.11e-06	177	163	7	1b872d3b1e0fca138362098590a634d748dfca60
ToppCell	VE-plasma-\|VE / Condition, Cell_class and T cell subcluster	ELL2 IGKV3D-15 IGKV2D-30 IGKV3-20 IGKV3-11 IGKV2-30 IGKV2-24	4.11e-06	177	163	7	3a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	4.60e-06	180	163	7	cd04d7bf92986a5b8a0193c9b92ec47da3929bac
ToppCell	cellseq-Immune-Lymphocytic_B\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	4.60e-06	180	163	7	663a800ab70e7ab7d13183417f9c1ed36907aa5e
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGRB3 IRS1 ARHGAP6 KCNT2 KCNQ5 GLI3 ROBO2	4.60e-06	180	163	7	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LINC00473 KIF26B ADGRB3 IRS1 COL23A1 ELL2 MTCL1	5.50e-06	185	163	7	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	10x5'-Liver-Lymphocytic_B_plasma\|Liver / Manually curated celltypes from each tissue	IGLV1-50 ELL2 IGLV1-40 IGKV3D-15 IGKV3-20 IGKV3-11 IGKV2-24	5.70e-06	186	163	7	a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCell	COVID-19-lung-Plasmablasts\|lung / Disease (COVID-19 only), tissue and cell type	IGLV1-40 IGLV1-36 KCNQ5 IGKV3D-11 IGKV3-15 IGKV3-11 IGKV2-30	5.70e-06	186	163	7	81caf67da9fed09c77b7ddcab9b0b8e4fab2de97
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	IGKV3D-15 IGKV3D-11 IGKV2D-30 CDCA5 IGKV3-20 IGKV3-15 IGKV3-11	5.70e-06	186	163	7	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LINC00473 THSD7A PAX8 GLI3 OSBPL10 VAV2 TNS3	5.70e-06	186	163	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 ADGRB3 IRS1 KCNT2 ROBO2 GREB1 UNC80	5.90e-06	187	163	7	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 THSD7A ADGRB3 ARHGAP6 GLI3 ROBO2 C7	6.33e-06	189	163	7	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KIF26B IRS1 COL23A1 ARHGAP6 KCNQ5 ROBO2 MTCL1	6.33e-06	189	163	7	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	COVID-19-lung-Plasmablasts\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IGLV1-40 IGLV1-36 KCNQ5 IGKV3D-11 IGKV3-15 IGKV3-11 IGKV2-30	6.33e-06	189	163	7	fdf6c945b352614885e646a5ef4bc576dee73895
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	LINC00473 KIF26B ADGRB3 IRS1 COL23A1 ROBO2 MTCL1	6.55e-06	190	163	7	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SGSH PALB2 BRWD3 MAP3K5 WAC STAB1 METTL27	6.55e-06	190	163	7	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 ADGRB3 IRS1 ARHGAP6 ROBO2 GREB1 UNC80	7.02e-06	192	163	7	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	COL6A3 KIF26B ADGRB3 ARHGAP6 TENM3 ROBO2 TNS3	7.02e-06	192	163	7	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	FLNB SP100 FLT1 THSD7A ATP10A ASAP2 KCNT2	7.26e-06	193	163	7	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL6A3 KIF26B ADGRB3 ARHGAP6 TENM3 ROBO2 C7	7.26e-06	193	163	7	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ELL2 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	7.26e-06	193	163	7	34f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	7.26e-06	193	163	7	282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	COL6A3 THSD7A ADGRB3 ARHGAP6 GLI3 ROBO2 C7	7.51e-06	194	163	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL6A3 ADGRB3 IRS1 ARHGAP6 PPARGC1B ROBO2 GREB1	7.51e-06	194	163	7	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ELL2 IGLV1-40 IGKV3D-15 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11	7.51e-06	194	163	7	f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 KIF26B ADGRB3 ARHGAP6 TENM3 PXDNL C7	7.51e-06	194	163	7	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	5'-Adult-LargeIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSIP2 IGLV1-40 IGKV3D-11 IGKV3-20 IGKV3-15 IGKV3-11 IGKV2-30	7.76e-06	195	163	7	600174e35574fe7c44dd923adcf43686e7b01e39
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL6A3 THSD7A ADGRB3 ARHGAP6 GLI3 ROBO2 C7	7.76e-06	195	163	7	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	COL6A3 KIF26B ADGRB3 ARHGAP6 TENM3 ROBO2 C7	7.76e-06	195	163	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL6A3 ADGRB3 JADE1 ARHGAP6 KCNT2 ELF2 C7	7.76e-06	195	163	7	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL6A3 ADGRB3 ARHGAP6 TENM3 GLI3 ROBO2 C7	8.03e-06	196	163	7	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGLV1-50 IGKV3D-15 IGKV3D-11 IGKV2D-30 IGKV3-20 IGKV3-15 IGKV3-11	8.03e-06	196	163	7	c38e7f533c619afe008de0e99042f7180c2da918
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FLT1 THSD7A STAB1 ASAP2 OSBPL10 ROBO2 ANKS1A	8.03e-06	196	163	7	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL6A3 ADGRB3 ARHGAP6 TENM3 GLI3 ROBO2 C7	8.03e-06	196	163	7	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	COL6A3 KIF26B ADGRB3 TENM3 GLI3 ROBO2 C7	8.30e-06	197	163	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 CUX2 KIF26B MAP3K5 TENM3 GLI3 C7	8.30e-06	197	163	7	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 ADGRB3 ARHGAP6 KCNT2 KCNQ5 ROBO2 CDRT15P3	8.30e-06	197	163	7	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 CUX2 KIF26B MAP3K5 TENM3 GLI3 C7	8.30e-06	197	163	7	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL6A3 KIF26B ADGRB3 TENM3 GLI3 ROBO2 C7	8.57e-06	198	163	7	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM61 SRRM4 DUSP15 PPEF2 MTMR7 ELAPOR1 UNC80	8.57e-06	198	163	7	2591e08e3fbee86ac40f11becd8147d6d39fded6
Disease	Neurodevelopmental Disorders	TANC2 TRIP12 WAC CASK SETD5 WDFY3	7.66e-06	93	148	6	C1535926
Disease	cortical surface area measurement	TANC2 FLNB KIF26B AMZ1 TRIOBP DNAAF9 ARHGAP39 PKMYT1 KANSL1 GLI3 RP1L1 TNRC6A MTMR2 ROBO2 ELF2 NR3C2 MTCL1 BRD1 ZBTB18 ANKS1A	1.36e-05	1345	148	20	EFO_0010736
Disease	factor VIII measurement, coronary artery disease	FLT1 IGF2R LPA GPR149 ANKS1A	2.69e-04	113	148	5	EFO_0001645, EFO_0004630
Disease	factor XI measurement, coronary artery disease	FLT1 IGF2R LPA GPR149 ANKS1A	2.92e-04	115	148	5	EFO_0001645, EFO_0004694
Disease	response to norepinephrine-dopamine reuptake inhibitor	ASAP2 KCNQ5 ROBO2	2.95e-04	26	148	3	EFO_0007870
Disease	von Willebrand factor measurement, coronary artery disease	FLT1 OR13C5 LPA GPR149 ANKS1A	3.29e-04	118	148	5	EFO_0001645, EFO_0004629
Disease	Mental Retardation, X-Linked	BRWD3 CASK ARHGEF6	4.11e-04	29	148	3	C1136249
Disease	age at diagnosis, osteoarthritis	KANSL1 RP1L1	5.16e-04	7	148	2	EFO_0004918, MONDO_0005178
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	USP24 IGF2R LPA LYPD5 ANKRD17	6.52e-04	137	148	5	EFO_0004611, EFO_0008591
Disease	nephroblastoma (is_marker_for)	MYC FLT1 KDM4D	6.60e-04	34	148	3	DOID:2154 (is_marker_for)
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	BRWD3 CASK	6.86e-04	8	148	2	C0796250
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR7 MTMR2	8.79e-04	9	148	2	DOID:0111225 (implicated_via_orthology)
Disease	response to radiation	ATP10A BRWD3 ELAPOR1 ROBO2	1.02e-03	88	148	4	GO_0009314
Disease	smoking status measurement, chronic obstructive pulmonary disease	TRIM26 AMZ1 ASAP2 MTCL1	1.02e-03	88	148	4	EFO_0000341, EFO_0006527
Disease	cervical cancer	PAX8 OSBPL10 NR3C2	1.07e-03	40	148	3	MONDO_0002974
Disease	long QT syndrome (implicated_via_orthology)	ARHGAP6 KCNQ5	1.10e-03	10	148	2	DOID:2843 (implicated_via_orthology)
Disease	fibrinogen measurement, coronary artery disease	FLT1 IGF2R LPA GPR149 ANKS1A	1.10e-03	154	148	5	EFO_0001645, EFO_0004623
Disease	vital capacity	CACNA1S COL6A3 FLT1 AMZ1 TRIP12 TRIM66 RMI1 KANSL1 KCNQ5 GLI3 RTL9 MTCL1 ARHGEF6 OTOG ANKS1A	1.42e-03	1236	148	15	EFO_0004312
Disease	breast cancer (biomarker_via_orthology)	MYC FLT1	1.88e-03	13	148	2	DOID:1612 (biomarker_via_orthology)
Disease	familial hyperlipidemia	IGF2R SUGP2 LPA ELAPOR1	2.03e-03	106	148	4	MONDO_0001336
Disease	membranous glomerulonephritis (biomarker_via_orthology)	MAP3K5 C7	2.19e-03	14	148	2	DOID:10976 (biomarker_via_orthology)
Disease	coronary artery disease, factor VII measurement	FLT1 LPA GPR149 ANKS1A	2.40e-03	111	148	4	EFO_0001645, EFO_0004619
Disease	Inherited oocyte maturation defect	PATL2 ZP1	2.86e-03	16	148	2	cv:CN238505
Disease	Lipidemias	IRS1 PPARGC1B	3.23e-03	17	148	2	C1706412
Disease	Hyperlipidemia	IRS1 PPARGC1B	3.23e-03	17	148	2	C0020473
Disease	metabolic syndrome	CUX2 LPA RTL9 TNRC6A CDCA5	3.44e-03	200	148	5	EFO_0000195
Disease	level of Sphingomyelin (d34:1) in blood serum	USP24 ANKRD17	3.63e-03	18	148	2	OBA_2045175
Disease	Hemangiosarcoma	MYC FLT1	3.63e-03	18	148	2	C0018923
Disease	angina pectoris	FLT1 KCNH8 BRWD3 LPA	3.68e-03	125	148	4	EFO_0003913
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	FLT1 LPA ANKS1A	3.94e-03	63	148	3	EFO_0001645, EFO_0004792
Disease	esterified cholesterol measurement	ASAP2 IGF2R LPA ANKRD17	4.01e-03	128	148	4	EFO_0008589
Disease	Congenital hernia of foramen of Morgagni	IGF2R KCNQ5	4.04e-03	19	148	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF2R KCNQ5	4.04e-03	19	148	2	C0265700
Disease	cortical thickness	FLNB TRIOBP DNAAF9 STAB1 KANSL1 SETD5 GLI3 TNRC6A MTMR2 CDK5RAP2 ROBO2 MTCL1 ANKS1A	4.08e-03	1113	148	13	EFO_0004840
Disease	brain connectivity measurement	KIF26B AMZ1 TRIOBP KANSL1 PAX8 GLI3 ROBO2	4.17e-03	400	148	7	EFO_0005210
Disease	Coronary Arteriosclerosis	IRS1 LPA ANKS1A	4.30e-03	65	148	3	C0010054
Disease	Coronary Artery Disease	IRS1 LPA ANKS1A	4.30e-03	65	148	3	C1956346
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	TTLL5 STAB1 ELF2 CAMSAP1	4.35e-03	131	148	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	TTLL5 STAB1 ELF2 CAMSAP1	4.35e-03	131	148	4	C4552091
Disease	Juvenile arthritis	TTLL5 STAB1 ELF2 CAMSAP1	4.35e-03	131	148	4	C3495559
Disease	Juvenile psoriatic arthritis	TTLL5 STAB1 ELF2 CAMSAP1	4.35e-03	131	148	4	C3714758
Disease	citrulline measurement	KIF26B RP1L1	4.47e-03	20	148	2	EFO_0009777
Disease	Adenocarcinoma of prostate	MYC PALB2	4.47e-03	20	148	2	C0007112
Disease	MYELODYSPLASTIC SYNDROME	MYC CBL PALB2	4.68e-03	67	148	3	C3463824
Disease	Juvenile-Onset Still Disease	TTLL5 STAB1 ELF2 CAMSAP1	4.84e-03	135	148	4	C0087031
Disease	Congenital diaphragmatic hernia	IGF2R KCNQ5	4.93e-03	21	148	2	C0235833

Protein segments in the cluster

Peptide	Gene	Start	Entry
ACVRPSSSVTVACSG	nan	116	Q6ZRM9
TCNPSTITGTLSRLS	ADGRB2	1261	O60241
PRRRCASESSISSSN	BRD1	846	O95696
SLSTRPSSGCAQVLS	AAAS	226	Q9NRG9
TLGSASTSTPGRRSC	CDCA5	151	Q96FF9
NAAGTSRSESPVCSS	ELL2	296	O00472
SRSESPVCSSRDAVS	ELL2	301	O00472
ERPCGRSSSLSAANT	ARHGEF6	116	Q15052
AAASIRCSSRPSRDS	AMZ1	136	Q400G9
QCPLNATGTTSRRCS	ADGRB3	536	O60242
VSRGSSRSSCSQRRP	C2orf27A	171	P0DPF5
PVSRGSSRSSCSQRR	CDRT15P3	176	P0DPF6
AAPRRNSSASSSCHL	C17orf78	101	Q8N4C9
FTERSRPGVQISCSS	BRWD3	311	Q6RI45
ASTCSPSRASLLTGR	ARSG	81	Q96EG1
GISRNSSSPCISGTT	DOP1A	1231	Q5JWR5
TSSPLSQNDSCTGRS	ANKS1A	856	Q92625
RNRTCRPPSSSESSS	ANKRD17	76	O75179
SSGQSVSSNQRPCSS	CDSN	206	Q15517
SSRCSLEVSLNSPSA	CUX2	1386	O14529
STSRQRSRGSPSSTC	CBY3	36	A6NI87
CSSTPDNLSRTQSGS	CAMSAP1	1386	Q5T5Y3
RRFTPSCLTSGCSSI	ATP10A	611	O60312
SSATSTPCVSRLVTG	CDK5RAP2	1701	Q96SN8
ACFTTSRATSARPSV	RBM44	476	Q6ZP01
CRLSIDSQSSSSGPR	PAX8	206	Q06710
SRQSRSGVPSSSCVF	ARHGAP39	666	Q9C0H5
TSVAGSPARCSRISH	MTCL1	191	Q9Y4B5
GERATLSCRASQSVS	IGKV3D-11	36	A0A0A0MRZ8
RTFRCSQAGLSAVPS	LRRC3C	61	A6NJW4
SSCERDSPSTSRQSP	CASK	576	O14936
GQPASISCRSSQSLV	IGKV2D-30	36	A0A075B6S6
GISPCFSSRRSSEAS	GLI3	866	P10071
SRCSVSSPSNTNNRS	NR3C2	306	P08235
ASPGASARFTCTLRS	IGLV5-39	31	A0A0G2JS06
GSEFRSRQIPASTCS	GREB1	211	Q4ZG55
RVTISCTGSSSNIGA	IGLV1-50	36	A0A075B6I6
SICRSSQPLSGFSAR	MTMR7	201	Q9Y216
PRSSSFSCGSSRSVR	KRT85	491	P78386
TTDRGTSTDSPCRRS	MAPK8IP1	226	Q9UQF2
GQFCSNSSSIRRTAP	FOXD4L4	381	Q8WXT5
PTASSFTTRTAQCRN	ASAP2	21	O43150
RPTSIISFNSDCSAR	KIF26B	1206	Q2KJY2
DSLRTGRSRSSQSIC	KCNQ5	901	Q9NR82
QSCSSGRSTTIRVRC	ELAPOR1	806	Q6UXG2
RTDTNSSPSRASVCG	DYNC2I1	451	Q8WVS4
TSSNEGRRDSPTQTC	FSIP2	5651	Q5CZC0
RSATTAGSRAVSALC	COL23A1	26	Q86Y22
RTSRAPSVATVGSIC	FLNB	2101	O75369
STTGFVPCRRSSTSQ	PCNX1	2141	Q96RV3
RQRSSGGSSKALSTC	OR4K3	226	Q96R72
DTRGQVTSSCSSQRL	PGM2L1	116	Q6PCE3
VAPSNTGSRTTSVRC	NEK8	281	Q86SG6
TGLSCQGRSRTPART	PHRF1	581	Q9P1Y6
SSSSDGTCVAARTRP	KANSL1	581	Q7Z3B3
VCSSLPRRSAVSGTA	KDM4D	401	Q6B0I6
RSTSSSERASSPAQC	MTMR2	621	Q13614
CGSTRRCSSLNNLPS	FAM161B	126	Q96MY7
GERATLSCRASQSVS	IGKV3D-15	36	A0A087WSY6
LQDTSCRSASGPTLS	KCNT2	601	Q6UVM3
SEGRSKPSSTCSARL	OR13C5	231	Q8NGS8
LSALRTSGSQARATC	DEFA5	51	Q01523
GSTSDCLFPRRSSAS	IRS1	401	P35568
ASSPALSTCTESGRR	METTL27	226	Q8N6F8
LRRSGGCSPSSDTVF	GPR149	261	Q86SP6
SGTCTGQPSSRTSQK	PALB2	466	Q86YC2
PASSRSASSILCSSG	ARHGAP6	146	O43182
SLGQVAVSTCFSPRR	PATL2	266	C9JE40
LSTARFSDGRPCSSV	PXDNL	821	A1KZ92
RLGATSVTRACTTGS	GIMAP1	56	Q8WWP7
GNGATTSTIRSSCLV	HEATR5B	1016	Q9P2D3
SPSCTSTNRAAATGN	KDM1B	231	Q8NB78
TNTTSSRPRTECCSD	CCDC138	136	Q96M89
CTHPTQCRATSRSTG	DSC3	671	Q14574
TPHSRSTRENTSRCS	CACNA1S	1766	Q13698
STRENTSRCSAPATA	CACNA1S	1771	Q13698
TPTCTNAASVSRSGA	LINC00473	56	A8K010
SSSTQKGRDPQCTSS	GAS2L2	386	Q8NHY3
QLRPGSSSCTLSAST	DUSP15	246	Q9H1R2
SCSGGRSPTVRVSVV	COL6A3	1876	P12111
RGQSISVTSIRPCAA	C7	826	P10643
RTTRTNSTPLRAACF	FEM1A	111	Q9BSK4
SRGSPSVSCSRLRQV	DNAAF9	21	Q5TEA3
RGISSTTVTGRTCQS	LPA	1511	P08519
GTSSSSATLPITFRC	SLC1A6	386	P48664
SVRSGKNSSPINCSR	ELF2	336	Q15723
RQLQVISSSCGSTPS	FBXO41	341	Q8TF61
GDQPETRSVCSSRSS	MARCHF11	136	A6NNE9
IRTCHRPSCTTEGTT	LYPD5	181	Q6UWN5
RARDCGEPSLSSTTT	CDH26	246	Q8IXH8
GQPASISCRSSQSLV	IGKV2-24	36	A0A0C4DH68
GQPASISCRSSQSLV	IGKV2-30	36	P06310
GERATLSCRASQSVS	IGKV3-11	36	P04433
GERATLSCRASQSVS	IGKV3-15	36	P01624
GERATLSCRASQSVS	IGKV3-20	36	P01619
RVCVPSSASALGTAS	CBL	506	P22681
LSRQASTGSELCSPS	SASH3	141	O75995
CNRAPSSQTVGATTS	SPACA4	96	Q8TDM5
SVFRTPTSGQSVSTC	C18orf21	161	Q32NC0
ICGSPSSARSVSQSR	PYDC5	86	W6CW81
SRVSSIRSVGSCRVP	KRT36	26	O76013
AQKTSRSSSIPCSGS	PPEF2	366	O14830
SLTSVGQTRFRPDSC	OTOG	2286	Q6ZRI0
RCSSPLTRSSGSSLA	PHF20L1	596	A8MW92
GCPAATSSSSATRGR	MAP3K5	66	Q99683
LQRQRTALTSSAGSC	SERHL	176	Q9NQF3
TALTSSAGSCVRIPS	SERHL	181	Q9NQF3
QLSSITSSRNPACSG	IGF2R	2176	P11717
TAPIRASASGARSTS	RTL9	1016	Q8NET4
LKSRTPSRHSCSGSS	SRRM2	881	Q9UQ35
GTRTRNISCVVSDGS	THSD7A	1361	Q9UPZ6
AAPNPCSSSSRTTRR	LMF2	691	Q9BU23
EAPRQRVTISCSGSS	IGLV1-36	31	A0A0B4J1U3
RVTISCTGSSSNIGA	IGLV1-40	36	P01703
ERCFTTGSSSNTIPT	RMI1	266	Q9H9A7
ISNNRKCTSPRSSDT	MYC	336	P01106
GQFCSNSSSIRRTAP	FOXD4L5	381	Q5VV16
ETSSTSLSTSCPRGR	MIIP	56	Q5JXC2
RQLCSRSRSSSGSSP	PPARGC1B	846	Q86YN6
STPRLTTSERNLTCG	MRPL35	56	Q9NZE8
SDSRGTSSSHCRPQE	SETD5	1146	Q9C0A6
TSSSHCRPQENISSR	SETD5	1151	Q9C0A6
STGQRVCSVRSVDGS	SHKBP1	526	Q8TBC3
QRISPCSTLTSSTAS	TANC2	126	Q9HCD6
NSSARSTCSLTPALA	WAC	546	Q9BTA9
SGTPQRTSVCRHSSC	SEBOX	116	Q9HB31
QERVSGVPSSCSSSS	JADE1	536	Q6IE81
SSCTISSNGPGQRRE	TNS3	926	Q68CZ2
RNAFTSVSSCSPSRA	SGSH	61	P51688
SVSSCSPSRASLLTG	SGSH	66	P51688
PSCSLAGRGVSSRSA	OSBPL10	31	Q9BXB5
SSPSRATRDNPTTSC	TRIOBP	441	Q9H2D6
SPSRATRDNPTTSCA	TRIOBP	491	Q9H2D6
CSTVSPVSGINTRRS	SPICE1	796	Q8N0Z3
NTRRSSGATGNSCSP	SPICE1	806	Q8N0Z3
PQKASQTCSSSRGRA	APOL5	351	Q9BWW9
TTPSATRSCSGLVQT	TMEM61	191	Q8N0U2
NLTTCGRPVETASTR	VNN2	411	O95498
GSCSRSLASRAVQRS	ZC3H3	641	Q8IXZ2
DASSISTSQRISCRP	ZNF578	186	Q96N58
TAKRSSPINSQSRTC	UNC80	241	Q8N2C7
STSHRPRAASCRATA	WDFY3	3306	Q8IZQ1
TCSTACSTGTTRQRR	ZP1	541	P60852
QPLAISRGCTSSSSL	RNPC3	6	Q96LT9
RTTQSTSRPKCARAS	TNFAIP3	706	P21580
STPSTCTSSQQGQRR	RP1L1	626	Q8IWN7
VSQQSPCGRATSSSR	TNFSF14	181	O43557
LARTVGSTSTPRSRC	PKMYT1	446	Q99640
ACSASTSRTVAIPSG	KIF21A	1436	Q7Z4S6
SSPAESCRSKVRGTS	STYXL2	806	Q5VZP5
TVASPCSSTESLSQR	ZBTB18	211	Q99592
ETCSSSLRRGSGSQP	SP100	466	P23497
RSQSSESRPSSCESR	SRRM4	191	A7MD48
QASSGTCFPRKRISS	SUGP2	941	Q8IX01
DASSVSTSQRISCRP	ZNF808	186	Q8N4W9
TSSCARAARAPSATE	SCAND2P	201	Q9GZW5
GTPISFSCSRTRAGE	STAB1	1821	Q9NY15
SGRSSCLSSRSNSAL	TENM3	141	Q9P273
SRCSVSPTGDLTITN	ROBO2	366	Q9HCK4
CRSCTTDVRPISGSR	TRIM26	36	Q12899
SSLSPGRRCNTFSDS	ZBED6	11	P86452
IRNRLSSSGSNCSSG	USP24	1366	Q9UPU5
RTFISSGRSLGCQPS	ZGRF1	96	Q86YA3
ESVSARAPTCCSTGR	ZNF843	11	Q8N446
ERSASRASSRSPASC	VAV2	771	P52735
CRVRSGPSFKSVNTS	FLT1	311	P17948
GGRSCSSSSAVIVPQ	TRIP12	31	Q14669
QKTTGSCASTSRRGS	TRIP12	326	Q14669
SSSSGRTSGSLCPRD	TRIM66	771	O15016
SIRTRQSSECSESPS	TUT4	1411	Q5TAX3
TRCSPVSSVGNSALL	USP48	761	Q86UV5
RSGCNSASSTPDSTR	TOPBP1	1096	Q92547
QRGPVSSTSDSSTNC	TNRC6A	211	Q8NDV7
CRISSATASGQKPTT	TTLL5	1196	Q6EMB2
SLSPICTRGSSSRNK	KCNH8	726	Q96L42
RSPGASVSSSLTSLC	KIAA1522	561	Q9P206
RNTLANSCGTGIRSS	NACC2	386	Q96BF6
NSCGTGIRSSTSDPS	NACC2	391	Q96BF6