Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microfilament motor activity	MYH3 MYH6 MYH10 MYH11	6.53e-06	38	64	4	GO:0000146
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH3 MYH6 MYH10 MYH11 KIF5B	3.82e-05	118	64	5	GO:0003774
GeneOntologyMolecularFunction	telomerase RNA binding	XRN1 DKC1 PINX1	6.87e-05	25	64	3	GO:0070034
GeneOntologyMolecularFunction	calmodulin binding	MYH3 MYH6 MYH10 MYH11 SCN3A PLCB1	9.39e-05	230	64	6	GO:0005516
GeneOntologyMolecularFunction	ATP-dependent activity	MYH3 MYH6 MYH10 MYH11 ATP6V1G2 EP400 SMC1A KIF5B DHX30	1.41e-04	614	64	9	GO:0140657
GeneOntologyMolecularFunction	G-quadruplex RNA binding	XRN1 DHX30	4.48e-04	10	64	2	GO:0002151
GeneOntologyBiologicalProcess	lung induction	WNT2 WNT2B	2.84e-05	3	64	2	GO:0060492
GeneOntologyBiologicalProcess	foregut regionalization	WNT2 WNT2B	2.84e-05	3	64	2	GO:0060423
GeneOntologyBiologicalProcess	lung field specification	WNT2 WNT2B	2.84e-05	3	64	2	GO:0060424
GeneOntologyBiologicalProcess	regulation of telomere maintenance via telomerase	XRN1 DKC1 PINX1 TNKS	3.61e-05	60	64	4	GO:0032210
GeneOntologyBiologicalProcess	regulation of telomeric DNA binding	PINX1 TNKS	5.66e-05	4	64	2	GO:1904742
GeneOntologyBiologicalProcess	regulation of telomere maintenance via telomere lengthening	XRN1 DKC1 PINX1 TNKS	6.26e-05	69	64	4	GO:1904356
GeneOntologyBiologicalProcess	primary lung bud formation	WNT2 WNT2B	9.42e-05	5	64	2	GO:0060431
GeneOntologyBiologicalProcess	telomere maintenance via telomerase	XRN1 DKC1 PINX1 TNKS	9.62e-05	77	64	4	GO:0007004
GeneOntologyBiologicalProcess	membraneless organelle assembly	MYH3 MYH6 MYH10 MYH11 SMC1A ABT1 TNKS DHX30	1.07e-04	475	64	8	GO:0140694
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	XRN1 DKC1 PINX1 TNKS	1.29e-04	83	64	4	GO:0006278
GeneOntologyBiologicalProcess	protein localization to chromosome, telomeric region	DKC1 PINX1 TNKS	1.33e-04	32	64	3	GO:0070198
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance via telomere lengthening	XRN1 PINX1 TNKS	1.45e-04	33	64	3	GO:1904357
GeneOntologyBiologicalProcess	myofibril assembly	MYH3 MYH6 MYH10 MYH11	1.48e-04	86	64	4	GO:0030239
GeneOntologyBiologicalProcess	striated muscle cell development	MYH3 MYH6 MYH10 MYH11	1.69e-04	89	64	4	GO:0055002
GeneOntologyBiologicalProcess	regulation of chromosome organization	BCL7C BCL7B XRN1 DKC1 PINX1 TNKS	1.74e-04	266	64	6	GO:0033044
GeneOntologyBiologicalProcess	telomere maintenance via telomere lengthening	XRN1 DKC1 PINX1 TNKS	1.76e-04	90	64	4	GO:0010833
GeneOntologyBiologicalProcess	regulation of branching involved in lung morphogenesis	WNT2 WNT2B	1.97e-04	7	64	2	GO:0061046
GeneOntologyBiologicalProcess	muscle cell differentiation	MYH3 MYH6 MYH10 MYH11 SUPT6H LAMC1 FLOT1 ALPK2	2.28e-04	531	64	8	GO:0042692
GeneOntologyBiologicalProcess	chromosome organization	SMC1A BCL7C BCL7B XRN1 DKC1 PINX1 TNKS TOP1MT DHX30	2.54e-04	686	64	9	GO:0051276
GeneOntologyBiologicalProcess	atrial cardiac muscle tissue morphogenesis	MYH6 WNT2	2.62e-04	8	64	2	GO:0055009
GeneOntologyBiologicalProcess	mitotic cell cycle process	MYH10 SMC1A BCL7C BCL7B PKHD1 PLCB1 PINX1 EXOC3 RDX TNKS	2.80e-04	854	64	10	GO:1903047
GeneOntologyBiologicalProcess	muscle structure development	MYH3 MYH6 MYH10 MYH11 SUPT6H WNT2 PLCB1 LAMC1 FLOT1 ALPK2	2.90e-04	858	64	10	GO:0061061
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance	XRN1 PINX1 TNKS	3.00e-04	42	64	3	GO:0032205
GeneOntologyBiologicalProcess	regulation of DNA metabolic process	EP400 SUPT6H BCL7C BCL7B XRN1 DKC1 PINX1 TNKS	3.42e-04	564	64	8	GO:0051052
GeneOntologyBiologicalProcess	regulation of telomere maintenance	XRN1 DKC1 PINX1 TNKS	4.07e-04	112	64	4	GO:0032204
GeneOntologyBiologicalProcess	DNA metabolic process	EP400 SUPT6H SMC1A BCL7C BCL7B XRN1 CDADC1 DKC1 PINX1 TNKS TOP1MT	4.49e-04	1081	64	11	GO:0006259
GeneOntologyBiologicalProcess	iris morphogenesis	WNT2 WNT2B	5.12e-04	11	64	2	GO:0061072
GeneOntologyBiologicalProcess	cardiac muscle cell development	MYH6 MYH10 MYH11 ALPK2	5.63e-04	122	64	4	GO:0055013
GeneOntologyBiologicalProcess	organelle assembly	MYH3 MYH6 MYH10 MYH11 SMC1A IFT81 PKHD1 RDX ABT1 TNKS DHX30	6.90e-04	1138	64	11	GO:0070925
GeneOntologyBiologicalProcess	cardiac cell development	MYH6 MYH10 MYH11 ALPK2	7.57e-04	132	64	4	GO:0055006
GeneOntologyCellularComponent	myosin filament	MYH3 MYH6 MYH10 MYH11	1.09e-06	25	66	4	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH3 MYH6 MYH10 MYH11	1.75e-06	28	66	4	GO:0016460
GeneOntologyCellularComponent	muscle myosin complex	MYH3 MYH6 MYH11	1.63e-05	16	66	3	GO:0005859
GeneOntologyCellularComponent	myosin complex	MYH3 MYH6 MYH10 MYH11	3.62e-05	59	66	4	GO:0016459
GeneOntologyCellularComponent	actin cytoskeleton	MYH3 MYH6 MYH10 MYH11 APC2 RDX FLOT1 STOML2	4.46e-04	576	66	8	GO:0015629
GeneOntologyCellularComponent	midbody	MYH10 CCDC124 APC2 EXOC3 RDX	6.82e-04	222	66	5	GO:0030496
GeneOntologyCellularComponent	ATPase complex	ATP6V1G2 EP400 BCL7C BCL7B	7.42e-04	129	66	4	GO:1904949
GeneOntologyCellularComponent	GBAF complex	BCL7C BCL7B	8.72e-04	14	66	2	GO:0140288
Domain	Myosin_N	MYH3 MYH6 MYH10 MYH11	1.66e-07	15	64	4	PF02736
Domain	Myosin_N	MYH3 MYH6 MYH10 MYH11	1.66e-07	15	64	4	IPR004009
Domain	Myosin_tail_1	MYH3 MYH6 MYH10 MYH11	3.70e-07	18	64	4	PF01576
Domain	Myosin_tail	MYH3 MYH6 MYH10 MYH11	3.70e-07	18	64	4	IPR002928
Domain	Myosin-like_IQ_dom	MYH3 MYH6 MYH10 MYH11	4.67e-07	19	64	4	IPR027401
Domain	-	MYH3 MYH6 MYH10 MYH11	4.67e-07	19	64	4	4.10.270.10
Domain	IQ	MYH3 MYH6 MYH10 MYH11 SCN3A	4.41e-06	71	64	5	PF00612
Domain	IQ	MYH3 MYH6 MYH10 MYH11 SCN3A	8.45e-06	81	64	5	SM00015
Domain	Myosin_head_motor_dom	MYH3 MYH6 MYH10 MYH11	8.48e-06	38	64	4	IPR001609
Domain	MYOSIN_MOTOR	MYH3 MYH6 MYH10 MYH11	8.48e-06	38	64	4	PS51456
Domain	Myosin_head	MYH3 MYH6 MYH10 MYH11	8.48e-06	38	64	4	PF00063
Domain	MYSc	MYH3 MYH6 MYH10 MYH11	8.48e-06	38	64	4	SM00242
Domain	Wnt2	WNT2 WNT2B	1.16e-05	2	64	2	IPR009140
Domain	IQ_motif_EF-hand-BS	MYH3 MYH6 MYH10 MYH11 SCN3A	1.42e-05	90	64	5	IPR000048
Domain	IQ	MYH3 MYH6 MYH10 MYH11 SCN3A	1.66e-05	93	64	5	PS50096
Domain	BCL_N	BCL7C BCL7B	3.46e-05	3	64	2	PF04714
Domain	BCL7	BCL7C BCL7B	3.46e-05	3	64	2	IPR006804
Domain	Myosin_S1_N	MYH10 MYH11	1.15e-04	5	64	2	IPR008989
Domain	P-loop_NTPase	MYH3 MYH6 MYH10 GBP6 MYH11 EP400 SMC1A KIF5B DHX30 NLRP6	5.77e-04	848	64	10	IPR027417
Domain	Band_7	FLOT1 STOML2	6.23e-04	11	64	2	IPR001107
Domain	Band_7	FLOT1 STOML2	6.23e-04	11	64	2	PF01145
Domain	PHB	FLOT1 STOML2	6.23e-04	11	64	2	SM00244
Domain	Wnt	WNT2 WNT2B	1.90e-03	19	64	2	IPR005817
Domain	Wnt_CS	WNT2 WNT2B	1.90e-03	19	64	2	IPR018161
Domain	wnt	WNT2 WNT2B	1.90e-03	19	64	2	PF00110
Domain	WNT1	WNT2 WNT2B	1.90e-03	19	64	2	SM00097
Domain	WNT1	WNT2 WNT2B	1.90e-03	19	64	2	PS00246
Domain	DNA/RNA_helicase_DEAH_CS	EP400 DHX30	6.39e-03	35	64	2	IPR002464
Pathway	KEGG_TIGHT_JUNCTION	MYH3 MYH6 MYH10 MYH11 EXOC3	9.14e-05	132	49	5	M11355
Pathway	KEGG_VIRAL_MYOCARDITIS	MYH3 MYH6 MYH10 MYH11	9.98e-05	70	49	4	M12294
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	NEFL MYH3 MYH6 PRDM8 MYH10 MYH11 ATP6V1G2 UBXN4 IFT81 XRN1 PKHD1 NFXL1 DKC1 RDX KIF5B CFAP210 TOP1MT RPL7A	1.22e-10	1442	66	18	35575683
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CUTA MYH10 MYH11 CCDC124 EP400 CDK12 SELENOH BCL7B DKC1 PINX1 RDX LAMC1 ABT1 KIF5B FLOT1 GADD45GIP1 LRRFIP1	4.91e-10	1371	66	17	36244648
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NEFL EP400 SUPT6H SMC1A C19orf47 DKC1 EXOC3 LAMC1 KIF5B FLOT1 GADD45GIP1 RPL7A NCDN STOML2 DHX30	6.46e-10	1024	66	15	24711643
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	NEFL MYH6 MYH10 MYH11 ATP6V1G2 SARS1 XRN1 RDX KIF5B FLOT1 TRIP11 RPL7A NCDN STOML2 LRRFIP1 DHX30	7.60e-09	1431	66	16	37142655
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GPRASP1 NEFL MYH10 CCDC124 APC2 PLCB1 RDX TNKS KIF5B TRIP11 NCDN STOML2 LRRFIP1	2.73e-08	963	66	13	28671696
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	NEFL MYH10 MYH11 UBXN4 SUPT6H SMC1A RDX LAMC1 KIF5B FLOT1 RPL7A LRRFIP1	5.94e-08	847	66	12	35235311
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	CDK12 SMC1A C19orf47 XRN1 DKC1 PINX1 BUD13 ABT1 RPL7A LRRFIP1 DHX30	1.80e-07	759	66	11	35915203
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MYH10 MYH11 SMC1A DKC1 RDX ABT1 KIF5B TOP1MT FLOT1 RPL7A LRRFIP1 DHX30	2.02e-07	949	66	12	36574265
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	MYH10 CCDC124 SARS1 SUPT6H SMC1A DKC1 RDX KIF5B RPL7A NCDN LRRFIP1 DHX30 SPINK5 RPAP2	3.40e-07	1415	66	14	28515276
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	MYH10 CDK12 SUPT6H SMC1A DKC1 PINX1 EXOC3 KIF5B DHX30 RPAP2	4.17e-07	653	66	10	33742100
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NEFL MYH10 CCDC124 EP400 CDK12 SUPT6H SMC1A DKC1 BUD13 FLOT1 RPL7A DHX30	8.10e-07	1082	66	12	38697112
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MYH10 CCDC124 EP400 CDK12 XRN1 DKC1 RDX KIF5B TRIP11 RPL7A DHX30	1.38e-06	934	66	11	33916271
Pubmed	Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.	MYH6 MYH10 MYH11	1.42e-06	12	66	3	8424456
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	MYH10 GBP6 CCDC124 SMC1A KIF5B RPL7A ALPK2 STOML2 LRRFIP1 DHX30	2.86e-06	809	66	10	32129710
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	SMC1A XRN1 DKC1 PINX1 KIF5B RPL7A LRRFIP1 DHX30	2.98e-06	469	66	8	37314180
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MYH10 SARS1 SMC1A XRN1 BUD13 RDX KIF5B FLOT1 RPL7A STOML2 DHX30 RPAP2	3.52e-06	1247	66	12	27684187
Pubmed	Differential regulation of WNT2 and WNT2B expression in human cancer.	WNT2 WNT2B	3.55e-06	2	66	2	11712082
Pubmed	Constriction velocities of renal afferent and efferent arterioles of mice are not related to SMB expression.	MYH10 MYH11	3.55e-06	2	66	2	16316347
Pubmed	Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue.	MYH10 MYH11	3.55e-06	2	66	2	10906735
Pubmed	Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.	MYH10 MYH11	3.55e-06	2	66	2	7916668
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	EP400 DKC1 BUD13 RDX RPL7A DHX30	7.33e-06	245	66	6	21182205
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	NEFL MYH10 CCDC124 SARS1 SMC1A DKC1 RPL7A DHX30	8.14e-06	538	66	8	28524877
Pubmed	Endogenous retinoic acid signaling colocalizes with advanced expression of the adult smooth muscle myosin heavy chain isoform during development of the ductus arteriosus.	MYH6 MYH11	1.06e-05	3	66	2	8620598
Pubmed	Effects of h1-calponin ablation on the contractile properties of bladder versus vascular smooth muscle in mice lacking SM-B myosin.	MYH10 MYH11	1.06e-05	3	66	2	16973711
Pubmed	Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.	MYH3 MYH6	1.06e-05	3	66	2	1939265
Pubmed	The BCL7 gene family: deletion of BCL7B in Williams syndrome.	BCL7C BCL7B	1.06e-05	3	66	2	9931421
Pubmed	Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.	MYH3 MYH6	1.06e-05	3	66	2	1694848
Pubmed	Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon.	BCL7C BCL7B	1.06e-05	3	66	2	8605326
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	XRN1 EXOC3 RDX KIF5B FLOT1 TRIP11 RPL7A LRRFIP1	1.16e-05	565	66	8	25468996
Pubmed	Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis.	MYH11 WNT2 WNT2B	1.46e-05	25	66	3	15136151
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	CUTA MYH11 CCDC124 SARS1 DKC1 KIF5B FLOT1 STOML2 DHX30	1.72e-05	786	66	9	29128334
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYH10 SMC1A NFXL1 DKC1 PINX1 EXOC3 RPL7A DHX30	1.81e-05	601	66	8	33658012
Pubmed	The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.	MYH10 CCDC124 SELENOH DKC1 RDX FLOT1 RPL7A STOML2	1.87e-05	604	66	8	37616343
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	CCDC124 EP400 SUPT6H DKC1 ABT1 DHX30 RPAP2	2.02e-05	440	66	7	34244565
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	UBXN4 SARS1 SUPT6H IFT81 NFXL1 EXOC3 LAMC1 FLOT1 RPL7A NCDN STOML2 DHX30	2.06e-05	1487	66	12	33957083
Pubmed	The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.	APC2 TNKS	2.12e-05	4	66	2	27068743
Pubmed	Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.	MYH10 RDX	2.12e-05	4	66	2	20660156
Pubmed	The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells.	CDK12 BUD13	2.12e-05	4	66	2	36463205
Pubmed	Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development.	MYH6 MYH10	2.12e-05	4	66	2	8482409
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	EP400 DKC1 RPL7A NCDN DHX30 RPAP2	2.31e-05	300	66	6	28561026
Pubmed	A protein interaction landscape of breast cancer.	MYH10 SARS1 BCL7C DKC1 TRIP11 RPL7A DHX30 RPAP2	2.64e-05	634	66	8	34591612
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GPRASP1 NEFL SMC1A IFT81 APC2 RDX TNKS FLOT1 TRIP11 LRRFIP1 DHX30	2.79e-05	1285	66	11	35914814
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	MYH6 MYH10 MYH11 SPINK5	2.91e-05	92	66	4	37343697
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	MYH10 MYH11 KIF5B FLOT1 RPL7A	3.23e-05	191	66	5	33762435
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NEFL MYH10 SUPT6H XRN1 KIF5B RPL7A STOML2 DHX30	3.26e-05	653	66	8	22586326
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	MYH10 SH2D4A IFT81 XRN1 DKC1 KIF5B FLOT1 NCDN FAM110B	3.26e-05	853	66	9	28718761
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	ATP6V1G2 SUPT6H PLCB1 RDX TNKS RPL7A DHX30	3.30e-05	475	66	7	31040226
Pubmed	Developmental regulation of myosin gene expression in mouse cardiac muscle.	MYH3 MYH6	3.53e-05	5	66	2	2277065
Pubmed	Telokin expression is restricted to smooth muscle tissues during mouse development.	MYH10 MYH11	3.53e-05	5	66	2	11121372
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH10 MYH11 XRN1 LAMC1 DHX30	4.22e-05	202	66	5	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYH10 MYH11 PKHD1 LAMC1 LRRFIP1	4.22e-05	202	66	5	24639526
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYH3 SUPT6H SMC1A RDX LAMC1 TNKS TRIP11	4.39e-05	497	66	7	23414517
Pubmed	ABCE1 is a highly conserved RNA silencing suppressor.	SMC1A DKC1 KIF5B FLOT1 GADD45GIP1	4.42e-05	204	66	5	25659154
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYH10 EP400 SMC1A XRN1 NFXL1 DKC1 EXOC3 KIF5B RPL7A STOML2 DHX30	4.46e-05	1353	66	11	29467282
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	UBXN4 EXOC3 KIF5B FLOT1 TRIP11 LRRFIP1	4.56e-05	339	66	6	37232246
Pubmed	Wnt11 promotes cardiomyocyte development by caspase-mediated suppression of canonical Wnt signals.	MYH6 WNT2 WNT2B	5.25e-05	38	66	3	21041481
Pubmed	Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts.	MYH3 MYH6	5.29e-05	6	66	2	28381556
Pubmed	Wnt/β-catenin pathway is regulated by PITX2 homeodomain protein and thus contributes to the proliferation of human ovarian adenocarcinoma cell, SKOV-3.	WNT2 WNT2B	5.29e-05	6	66	2	23250740
Pubmed	Both smooth and skeletal muscle precursors are present in foetal mouse oesophagus and they follow different differentiation pathways.	MYH3 MYH11	5.29e-05	6	66	2	10906778
Pubmed	Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.	BCL7C BCL7B	5.29e-05	6	66	2	23644491
Pubmed	The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton.	NEFL RDX	5.29e-05	6	66	2	12226091
Pubmed	The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function.	BCL7C BCL7B	5.29e-05	6	66	2	29213114
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GPRASP1 MYH10 UBXN4 XRN1 PLCB1 KIF5B FLOT1 RPL7A STOML2 LRRFIP1	5.44e-05	1139	66	10	36417873
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	NEFL SMC1A SELENOH DKC1 PINX1 RDX TNKS FLOT1 STOML2	5.66e-05	916	66	9	32203420
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	MYH11 CCDC124 CDK12 SMC1A SCN3A BUD13 KIF5B GADD45GIP1 RPL7A DHX30	6.03e-05	1153	66	10	29845934
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	SH2D4A SMC1A BCL7B DKC1 EXOC3 BUD13 FLOT1 NCDN FAM110B DHX30	6.12e-05	1155	66	10	20360068
Pubmed	AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.	MYH3 MYH6 WNT2	6.13e-05	40	66	3	24680892
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MYH10 SARS1 SUPT6H SMC1A DKC1 RDX KIF5B FLOT1 RPL7A STOML2 DHX30	7.11e-05	1425	66	11	30948266
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	MYH10 CDK12 SMC1A DKC1 BUD13 ABT1 RPL7A DHX30	7.19e-05	731	66	8	29298432
Pubmed	Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.	XRN1 DKC1	7.40e-05	7	66	2	26950371
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH3 MYH6	7.40e-05	7	66	2	16819597
Pubmed	Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.	MYH6 MYH10	7.40e-05	7	66	2	21126233
Pubmed	An essential role for connexin43 gap junctions in mouse coronary artery development.	MYH6 MYH11	7.40e-05	7	66	2	11934868
Pubmed	Characterization of LGALS3 (galectin-3) as a player in DNA damage response.	MYH10 LAMC1 RPL7A	9.35e-05	46	66	3	24755837
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH3 MYH6	9.86e-05	8	66	2	3864153
Pubmed	Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction.	MYH10 MYH11	9.86e-05	8	66	2	33424621
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	UBXN4 CCDC124 XRN1 NFXL1 RDX KIF5B TRIP11	1.01e-04	568	66	7	37774976
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SH2D4A EP400 CDK12 SMC1A BCL7C DKC1 BUD13 LRRFIP1	1.07e-04	774	66	8	15302935
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	NEFL MYH10 UBXN4 SARS1 SELENOH DKC1 FLOT1 TRIP11 GADD45GIP1 STOML2 DHX30	1.09e-04	1496	66	11	32877691
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	GPRASP1 MYH10 SUPT6H SMC1A DKC1 RDX TNKS KIF5B RPAP2	1.15e-04	1005	66	9	19615732
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	NEFL MYH10 MYH11 LAMC1	1.16e-04	131	66	4	28634551
Pubmed	Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis.	WNT2 WNT2B	1.27e-04	9	66	2	11092808
Pubmed	Multiple genetic variants in telomere pathway genes and breast cancer risk.	PINX1 TNKS	1.27e-04	9	66	2	20056641
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	MYH10 SUPT6H SMC1A C19orf47 DKC1 RPL7A DHX30	1.49e-04	605	66	7	28977666
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	GPRASP1 MYH3 PRDM8 ATP6V1G2 UBXN4 CCDC124 SARS1 SMC1A IFT81 KIF5B	1.55e-04	1293	66	10	15342556
Pubmed	Expression patterns of Wnt genes during development of an anterior part of the chicken eye.	WNT2 WNT2B	1.58e-04	10	66	2	16258938
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	CBR4 NEFL APC2 FLOT1 NCDN STOML2	1.68e-04	430	66	6	32581705
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	MYH10 EP400 SMC1A C19orf47 DKC1 RDX TOP1MT RPL7A STOML2 DHX30	1.81e-04	1318	66	10	30463901
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	NEFL SH2D4A SMC1A IFT81 CDADC1 EXOC3 TRIP11 STOML2 FAM110B DHX30	1.84e-04	1321	66	10	27173435
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	MYH10 CCDC124 SMC1A DKC1 KIF5B RPL7A	1.92e-04	441	66	6	31239290
Pubmed	De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair.	CDK12 SUPT6H	1.93e-04	11	66	2	31045206
Pubmed	Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development.	MYH3 MYH10	1.93e-04	11	66	2	20352047
Pubmed	Loss-of-function variants in myocardin cause congenital megabladder in humans and mice.	MYH6 MYH11	1.93e-04	11	66	2	31513549
Pubmed	Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of ATRX-Mutant Cancers to WEE1 Inhibition.	CDK12 SMC1A RPL7A	1.97e-04	59	66	3	31551363
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	MYH10 SARS1 SUPT6H SMC1A DKC1 RPL7A DHX30	2.06e-04	638	66	7	33239621
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	MYH10 KIF5B FLOT1	2.07e-04	60	66	3	20682791
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MYH10 EP400 SMC1A IFT81 NFXL1 KIF5B MXD4 GADD45GIP1	2.14e-04	857	66	8	25609649
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	EP400 IFT81 XRN1 PINX1 KIF5B FLOT1 RPAP2	2.21e-04	645	66	7	25281560
Pubmed	Molecular mechanisms underlying inner ear patterning defects in kreisler mutants.	NEFL WNT2B	2.31e-04	12	66	2	16325169
Pubmed	Gene trap screening as an effective approach for identification of Wnt-responsive genes in the mouse embryo.	WNT2 WNT2B	2.31e-04	12	66	2	15778975
Interaction	KIF20A interactions	NEFL MYH10 MYH11 SUPT6H APC2 XRN1 DKC1 TNKS CFAP210 TOP1MT FLOT1 TRIP11 GADD45GIP1 STOML2 DHX30	1.15e-06	1052	66	15	int:KIF20A
Interaction	CCDC8 interactions	NEFL EP400 SMC1A C19orf47 EXOC3 LAMC1 FLOT1 GADD45GIP1 RPL7A NCDN STOML2 DHX30	1.26e-06	656	66	12	int:CCDC8
Interaction	KCTD13 interactions	GPRASP1 NEFL MYH6 MYH10 MYH11 ATP6V1G2 SARS1 XRN1 RDX KIF5B FLOT1 TRIP11 RPL7A NCDN STOML2 LRRFIP1 DHX30	1.68e-06	1394	66	17	int:KCTD13
Interaction	ZNF2 interactions	CDK12 DKC1 BUD13 RPL7A DHX30	6.42e-06	80	66	5	int:ZNF2
Interaction	H2AC17 interactions	SELENOH XRN1 DKC1 BUD13 ABT1 GADD45GIP1 DHX30	1.07e-05	232	66	7	int:H2AC17
Interaction	FGF8 interactions	CDK12 IFT81 XRN1 DKC1 DHX30	2.77e-05	108	66	5	int:FGF8
Interaction	PRKRA interactions	CCDC124 CDK12 XRN1 DKC1 BUD13 ABT1 RPL7A DHX30	4.72e-05	400	66	8	int:PRKRA
Interaction	HECTD1 interactions	MYH10 CDK12 SMC1A C19orf47 XRN1 DKC1 PINX1 BUD13 ABT1 RPL7A LRRFIP1 DHX30	7.36e-05	984	66	12	int:HECTD1
Interaction	ABCE1 interactions	CCDC124 SMC1A DKC1 PINX1 KIF5B FLOT1 GADD45GIP1 RPL7A	7.96e-05	431	66	8	int:ABCE1
Interaction	PURG interactions	CDK12 XRN1 DKC1 BUD13 ABT1 DHX30	8.96e-05	223	66	6	int:PURG
Interaction	ZC3H3 interactions	DKC1 BUD13 ABT1 GADD45GIP1 RPL7A DHX30	9.65e-05	226	66	6	int:ZC3H3
Interaction	MYCN interactions	MYH10 EP400 CDK12 SELENOH BCL7C BCL7B DKC1 PINX1 BUD13 ABT1 GADD45GIP1 RPL7A DHX30 RPAP2	1.18e-04	1373	66	14	int:MYCN
Interaction	DGCR8 interactions	CDK12 DKC1 PINX1 ABT1 RPL7A DHX30	1.40e-04	242	66	6	int:DGCR8
Interaction	MAGEB2 interactions	CDK12 XRN1 DKC1 BUD13 ABT1 RPL7A DHX30	1.43e-04	349	66	7	int:MAGEB2
Interaction	OBSL1 interactions	NEFL CUTA EP400 SUPT6H SMC1A DKC1 FLOT1 RPL7A ALPK2 STOML2 DHX30	1.53e-04	902	66	11	int:OBSL1
Interaction	GMIP interactions	NEFL FLOT1 STOML2	1.87e-04	34	66	3	int:GMIP
Interaction	POLR1G interactions	EP400 SUPT6H SMC1A DKC1 PINX1 BUD13 RPL7A RPAP2	1.90e-04	489	66	8	int:POLR1G
Interaction	FGFBP1 interactions	CDK12 DKC1 PINX1 BUD13 ABT1 DHX30	1.94e-04	257	66	6	int:FGFBP1
GeneFamily	Myosin heavy chains	MYH3 MYH6 MYH10 MYH11	2.75e-08	15	40	4	1098
GeneFamily	Wnt family\|Endogenous ligands	WNT2 WNT2B	7.97e-04	19	40	2	360
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	GPRASP1 APC2	4.07e-03	43	40	2	409
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP6 CDK12 SMC1A XRN1 TNKS TRIP11	2.63e-07	178	66	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPRASP1 MYH6 XRN1 TNKS TRIP11	6.37e-06	176	66	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBXN4 CDK12 KIF5B TRIP11 LRRFIP1	8.55e-06	187	66	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBXN4 CDK12 RDX KIF5B LRRFIP1	8.78e-06	188	66	5	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-5\|TCGA-Thryoid / Sample_Type by Project: Shred V9	CUTA CCDC124 BCL7C FLOT1 GADD45GIP1	9.48e-06	191	66	5	f2fe8fe316e449f452075aa37d5e31917221a335
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-6\|TCGA-Endometrium / Sample_Type by Project: Shred V9	CUTA SELENOH BCL7C GADD45GIP1 STOML2	1.02e-05	194	66	5	84a539ce22ae6f5846f26a45cfc8beb559e2f5ea
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-1\|TCGA-Colorectal / Sample_Type by Project: Shred V9	BCL7C ABT1 GADD45GIP1 STOML2	3.69e-05	126	66	4	716726d0e39a6ef71565ad197b1a2b878dd4c01a
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MYH11 IFT81 WNT2B FAM110B	5.73e-05	141	66	4	dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sla_(Layer6a)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYH3 WNT2B NLRP6	6.33e-05	52	66	3	c134eb63bd1969af2af7f8de5989e19063533865
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sla_(Layer6a)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MYH3 WNT2B NLRP6	6.33e-05	52	66	3	14971277db09343d668e4f5a82ca2b6a92326251
ToppCell	BAL-Control-cDC_6\|Control / Compartment, Disease Groups and Clusters	GPRASP1 PRDM8 MYH10 IFT81	1.13e-04	168	66	4	65ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NEFL SUPT6H WNT2 NCDN	1.13e-04	168	66	4	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7\|TCGA-Endometrium / Sample_Type by Project: Shred V9	GPRASP1 PRDM8 MYH11 AOX1	1.13e-04	168	66	4	a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MYH10 RNF149 XRN1 PNPLA7	1.15e-04	169	66	4	0589f39d8e9468e42d25d30ff70bb7cb8b921628
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium\|TCGA-Endometrium / Sample_Type by Project: Shred V9	GPRASP1 PRDM8 MYH11 AOX1	1.18e-04	170	66	4	cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal\|TCGA-Endometrium / Sample_Type by Project: Shred V9	GPRASP1 PRDM8 MYH11 AOX1	1.18e-04	170	66	4	0bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue\|TCGA-Endometrium / Sample_Type by Project: Shred V9	GPRASP1 PRDM8 MYH11 AOX1	1.18e-04	170	66	4	516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PINX1 TNKS GOLGA8Q NCDN	1.38e-04	177	66	4	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP6V1G2 WNT2 ABT1 FAM110B	1.41e-04	178	66	4	c87945146b2734141f07b39d268e0d8086ee0364
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEFL ATP6V1G2 SCN3A APC2	1.47e-04	180	66	4	368ff7fcfd21ad248f96a83a8b191040ba7d8670
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.67e-04	186	66	4	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.67e-04	186	66	4	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYH10 MYH11 SCN3A LRRFIP1	1.74e-04	188	66	4	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.77e-04	189	66	4	32e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	CBR4 MYH6 ALPK2 LRRFIP1	1.77e-04	189	66	4	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.77e-04	189	66	4	385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.81e-04	190	66	4	9cd147a174017ebda23cc47b6d4552d898acd092
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.85e-04	191	66	4	a261f0738d974784bbdd60f23092bfbcca464459
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH10 WNT2 SCN3A LAMC1	1.85e-04	191	66	4	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH10 WNT2 SCN3A LAMC1	1.85e-04	191	66	4	6594398cc8151c73696391a43ac110c10283dab1
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH10 WNT2 SCN3A LAMC1	1.85e-04	191	66	4	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC1A XRN1 LAMC1 TRIP11	1.85e-04	191	66	4	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH10 WNT2 SCN3A LAMC1	1.88e-04	192	66	4	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 WNT2 SCN3A LAMC1	1.92e-04	193	66	4	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 WNT2 SCN3A LAMC1	1.92e-04	193	66	4	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 WNT2 SCN3A LAMC1	1.92e-04	193	66	4	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH10 WNT2 SCN3A LAMC1	1.92e-04	193	66	4	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYH10 WNT2 AOX1 LAMC1	1.92e-04	193	66	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	COVID-19_Convalescent-PLT_4\|COVID-19_Convalescent / Disease Group and Platelet Clusters	UBXN4 SELENOH TRIP11 STOML2	1.96e-04	194	66	4	ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYH10 WNT2 AOX1 LAMC1	2.00e-04	195	66	4	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYH10 WNT2 AOX1 LAMC1	2.00e-04	195	66	4	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	MYH10 WNT2 AOX1 LAMC1	2.04e-04	196	66	4	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYH10 WNT2 AOX1 LAMC1	2.04e-04	196	66	4	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	NEFL SCN3A PLCB1 NCDN	2.04e-04	196	66	4	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Syt15_(Medial_habenula)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MYH6 WNT2B SPINK5	2.04e-04	77	66	3	7f624e9262bd0dc2ac4176f43c91a4bc0f521fe5
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEFL ATP6V1G2 SCN3A APC2	2.08e-04	197	66	4	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	TCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-5\|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9	SELENOH BCL7C PINX1 GADD45GIP1	2.08e-04	197	66	4	b33999eadabecc94086e9a1fa26c5978729158e1
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEFL ATP6V1G2 SCN3A APC2	2.08e-04	197	66	4	f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MYH11 ATP6V1G2 SCN3A GOLGA8Q	2.12e-04	198	66	4	0f1feed8a37293ae02465909f99548ab58dc7ce5
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYH10 WNT2 AOX1 LAMC1	2.12e-04	198	66	4	7f728ca6d5317890c6fcde3ce6c10c0970d49a05
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEFL ATP6V1G2 SCN3A APC2	2.12e-04	198	66	4	800ade4261695f2efd869d2b1243571de963c431
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYH10 WNT2 AOX1 LAMC1	2.12e-04	198	66	4	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	MYH10 MYH11 WNT2 AOX1	2.16e-04	199	66	4	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	(00)_Basal\|World / shred by cell type by condition	GBP6 DKC1 RPL7A SPINK5	2.16e-04	199	66	4	bc0201e77a1690e3e0a6ecd05cd105e1f5c0ba7b
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 SCN3A NCDN FAM110B	2.20e-04	200	66	4	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 ATP6V1G2 SCN3A FAM110B	2.20e-04	200	66	4	84e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCell	Striatum-Neuronal\|Striatum / BrainAtlas - Mouse McCarroll V32	GPRASP1 ATP6V1G2 PLCB1 NCDN	2.20e-04	200	66	4	c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYH10 WNT2 AOX1 LAMC1	2.20e-04	200	66	4	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 ATP6V1G2 SCN3A FAM110B	2.20e-04	200	66	4	1decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH11 PLCB1 ABT1 STOML2	2.20e-04	200	66	4	49ad6e2337886367fbfa2a7c7366687b701ddf39
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 ATP6V1G2 SCN3A NCDN	2.20e-04	200	66	4	04699d1149a143b96d6f292c0d70c4d3e6dfc611
ToppCell	Parenchymal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYH10 MYH11 WNT2 AOX1	2.20e-04	200	66	4	2e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GBP6 XRN1 PINX1 RDX	2.20e-04	200	66	4	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	PRDM8 SCN3A NCDN FAM110B	2.20e-04	200	66	4	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SH2D4A SPINK5 NLRP6	2.93e-04	87	66	3	aaca22b97a42a1c4a10c5da708d1462101814386
Drug	oxovanadium	MYH3 MYH6 MYH10 MYH11 WNT2 AOX1	1.10e-06	120	64	6	CID000024411
Drug	fast white	MYH3 MYH6 MYH10 MYH11	5.86e-06	42	64	4	CID000024008
Drug	formycin triphosphate	MYH3 MYH6 MYH10 MYH11	1.28e-05	51	64	4	CID000122274
Drug	4-amino-2,6-dinitrotoluene	EP400 SUPT6H WNT2 SMC1A IFT81 BCL7C XRN1 DKC1 FLOT1	1.95e-05	541	64	9	ctd:C035207
Drug	purealin	MYH3 MYH6 MYH10 MYH11	2.15e-05	58	64	4	CID006419303
Drug	Fenton's reagent	AOX1 RDX SIL1	2.72e-05	21	64	3	CID000160257
Drug	AC1L1DSW	NEFL XRN1 PINX1 RPL7A	4.53e-05	70	64	4	CID000002493
Drug	AC1L212F	AOX1 FLOT1	4.65e-05	4	64	2	CID000013118
Drug	picrolonic acid	AOX1 FLOT1	4.65e-05	4	64	2	CID000068369
Drug	BAPPs	NEFL SIL1	4.65e-05	4	64	2	CID000134312
Drug	AC1L3UXH	AOX1 FLOT1	4.65e-05	4	64	2	CID000065446
Drug	clenbuterol	MYH3 MYH6 MYH10 MYH11 SCN3A	4.99e-05	142	64	5	CID000002783
Disease	oleoyl-oleoyl-glycerol (18:1/18:1) [1] measurement	BCL7B BUD13	6.07e-05	6	60	2	EFO_0800497
Disease	Agents acting on the renin-angiotensin system use measurement	PRDM8 MYH11 WNT2B PKHD1 PLCB1 PINX1	6.12e-05	335	60	6	EFO_0009931
Disease	cryptic phenotype measurement	PRDM8 WNT2B PLCB1	1.22e-04	47	60	3	EFO_0021487
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0110454 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH3 MYH6	1.81e-04	10	60	2	DOID:0111596 (implicated_via_orthology)
Disease	smoking status measurement, forced expiratory volume	PKHD1 RDX	2.21e-04	11	60	2	EFO_0004314, EFO_0006527
Disease	oleoyl-linoleoyl-glycerol (18:1/18:2) [1] measurement	BCL7B BUD13	2.21e-04	11	60	2	EFO_0800332
Disease	distal myopathy (implicated_via_orthology)	MYH3 MYH6	2.65e-04	12	60	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH3 MYH6	2.65e-04	12	60	2	DOID:2106 (implicated_via_orthology)
Disease	smoking status measurement, systolic blood pressure	PRDM8 WNT2B PINX1 TNKS	2.91e-04	156	60	4	EFO_0006335, EFO_0006527
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH3 MYH6	3.13e-04	13	60	2	DOID:397 (implicated_via_orthology)
Disease	smoking status measurement, diastolic blood pressure	PRDM8 WNT2B PINX1 TNKS	3.13e-04	159	60	4	EFO_0006336, EFO_0006527
Disease	distal arthrogryposis (implicated_via_orthology)	MYH3 MYH6	4.20e-04	15	60	2	DOID:0050646 (implicated_via_orthology)
Disease	vision disorder	MYH10 RDX	4.79e-04	16	60	2	MONDO_0021084
Disease	coronary artery disease	PRDM8 MYH11 SH2D4A CDK12 PKHD1 BUD13 LAMC1 TNKS LRRFIP1	6.51e-04	1194	60	9	EFO_0001645
Disease	Hypertriglyceridemia	BUD13 LAMC1	6.80e-04	19	60	2	EFO_0004211
Disease	Calcium channel blocker use measurement	PRDM8 WNT2B PLCB1 PINX1	9.38e-04	213	60	4	EFO_0009930
Disease	handedness	MYH3 ABT1 FLOT1	1.33e-03	106	60	3	EFO_0009902
Disease	Prostatic Neoplasms	CDK12 AOX1 LAMC1 SIL1 DHX30 SPINK5	1.56e-03	616	60	6	C0033578
Disease	Malignant neoplasm of prostate	CDK12 AOX1 LAMC1 SIL1 DHX30 SPINK5	1.56e-03	616	60	6	C0376358
Disease	Beta blocking agent use measurement	PRDM8 WNT2B PLCB1	1.64e-03	114	60	3	EFO_0009929
Disease	diastolic blood pressure, alcohol drinking	PRDM8 PINX1 TNKS	1.81e-03	118	60	3	EFO_0004329, EFO_0006336
Disease	amyotrophic lateral sclerosis (is_implicated_in)	NEFL AOX1	1.94e-03	32	60	2	DOID:332 (is_implicated_in)
Disease	mean arterial pressure, unipolar depression	PRDM8 WNT2B	1.94e-03	32	60	2	EFO_0003761, EFO_0006340

Protein segments in the cluster

Peptide	Gene	Start	Entry
KRAAEKVADARKRKA	ATP6V1G2	16	O95670
SLRAERIAKEKKALA	EP400	2516	Q96L91
KRFARLASKKAVEEL	BUD13	596	Q9BRD0
GAELSRKKKERAAAA	CDK12	396	Q9NYV4
AAKSAKATAALARRE	C19orf47	176	Q8N9M1
AKKSREREKSLEARA	ALPK2	1681	Q86TB3
AKEIARAVVEKRLAA	CUTA	81	O60888
KLDAKAVERLKSNSR	CDADC1	171	Q9BWV3
VAKGRRKAEAENKAA	DHX30	291	Q7L2E3
VRAETRSRAKDDIKK	BCL7B	6	Q9BQE9
DSEVQAKRAAKRVKI	AOX1	681	Q06278
AERVKALESALKEAK	KIF5B	871	P33176
KERRAAEEAKSAIAK	RDX	391	P35241
DFAREKTKAAGLVRK	MXD4	36	Q14582
KAVKAGDIDAKTRRR	NCDN	61	Q9UBB6
KRKASEIKEAEAKAA	NFXL1	831	Q6ZNB6
ERARAKAKREAAKEI	SPINK5	481	Q9NQ38
AEAKRDAGIREAKAK	FLOT1	181	O75955
ERAEAQERVAKKKSA	PINX1	241	Q96BK5
ERALSAVIATEKKKA	GOLGA8Q	181	H3BV12
LTDREKAVAVDRAKK	GBP6	481	Q6ZN66
KAVAVDRAKKEAAEK	GBP6	486	Q6ZN66
RKSDAIFRAAKKDLL	PNPLA7	446	Q6ZV29
DRFVRRKKKAAAAAG	ABT1	81	Q9ULW3
AKAKAKLALAVARID	APC2	841	O95996
KEKLASLEREASVKR	IFT81	366	Q8WYA0
VRAETRSRAKDDIKK	BCL7C	6	Q8WUZ0
VGFSRALAKEVARKK	CBR4	156	Q8N4T8
RRDFAVVKALAKLKA	CERKL	371	Q49MI3
KRLSAVERLEADKAK	FAM110B	46	Q8TC76
KRKKEARAAALAAAV	GADD45GIP1	196	Q8TAE8
RADAAKALAEEAAKK	LAMC1	1341	P11047
ERALSAVIATEKKKA	GOLGA8R	181	I6L899
EARKKASVEARLKAA	EXOC3	36	O60645
QVVAEAAKTAKRKRE	DKC1	436	O60832
RARRAEAKAAADAKK	CCDC124	16	Q96CT7
EDERKQRALAVASKK	MYH10	1606	P35580
ARKTLKRADARDVAA	NLRP6	81	P59044
KLAEARLAAKRAARA	LRRFIP1	21	Q32MZ4
KTKARARAKQEARSE	GPRASP1	386	Q5JY77
SKKKAAARDVTLENR	SARS1	491	P49591
SVARIAKLEKAKAKE	RPL7A	246	P62424
AKRSAFVEVKKAARA	PRDM8	381	Q9NQV8
SSKEDKARQAEVKRL	SIL1	146	Q9H173
SRDARNAEEKAKKAI	MYH3	1746	P11055
ETLKAIADSRAKRKR	PKHD1	3606	P08F94
SLAAIEKRAAEEKAK	SCN3A	21	Q9NY46
RNAEEKAKKAITDAA	MYH6	1751	P13533
TREAACLRAERKAKK	CFAP210	66	Q0VFZ6
EDERKQRALAAAAKK	MYH11	1606	P35749
AAKASRKKLKRVREE	SUPT6H	481	Q7KZ85
KDKVLVAARRNASAV	RNF149	121	Q8NC42
FVDAKERKGKDARAL	WNT2	171	P09544
DASKRKAELEAAVRK	RPAP2	36	Q8IXW5
AFAKRPRDDAKASEK	SSX6P	6	Q7RTT6
AAREADLAKVKKTLA	TNKS	496	O95271
RKRKAEAAVVAVAEK	SELENOH	6	Q8IZQ5
RFRSAKEAEDKIKKA	XRN1	101	Q8IZH2
VDKAAARKVLSREEK	TOP1MT	146	Q969P6
TSDEFEAARKRAKKA	SMC1A	1041	Q14683
EAARKRAKKAKQAFE	SMC1A	1046	Q14683
LRKSKAADEKRRSLA	SH2D4A	236	Q9H788
AVLAKAKAKAEAIRI	STOML2	246	Q9UJZ1
RRRAALEKSAKKDSK	PLCB1	961	Q9NQ66
AAEDREAKLRKKVTV	TRIP11	1601	Q15643
VKTALKSARDAIRNK	TTC37	6	Q6PGP7
ARFAKTKEEVEAAKA	UBXN4	281	Q92575
AFVDAKEKRLKDARA	WNT2B	201	Q93097
AKDEVSESRRLLKAK	NEFL	301	P07196