Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

POTEF POTEE POTEI POTEJ

3.46e-07111164GO:0098973
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

RASGRF1 PSG3 PSG4 PSG7 SHC1 ANGPT4 PSG8

2.64e-051491167GO:1990782
GeneOntologyMolecularFunctionstructural constituent of postsynapse

POTEF POTEE POTEI POTEJ

3.43e-05321164GO:0099186
GeneOntologyMolecularFunctionstructural molecule activity

FRAS1 H2AZ2 ANK1 POTEF NUP88 ADD1 PGM5 KRT73 POTEE HMCN1 H2AZ1 MACF1 POTEI POTEJ MUC5AC RPL4

5.72e-0589111616GO:0005198
GeneOntologyMolecularFunctiongranulocyte colony-stimulating factor receptor binding

PSG3 PSG4 PSG8

6.64e-05141163GO:0005130
GeneOntologyMolecularFunctionstructural constituent of synapse

POTEF POTEE POTEI POTEJ

1.02e-04421164GO:0098918
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

ANK1 POTEF ADD1 POTEE POTEI POTEJ

1.12e-041301166GO:0005200
GeneOntologyMolecularFunctionprotein phosphatase binding

ANK1 PSG3 PSG4 SHC1 SHOC2 JAK3 PSG8

2.28e-042101167GO:0019903
GeneOntologyMolecularFunctionGPI anchor binding

PSG3 PSG4 PSG8

3.11e-04231163GO:0034235
GeneOntologyMolecularFunctiongrowth factor receptor binding

PSG3 PSG4 SHC1 ANGPT4 PSG8 SOS1

5.24e-041731166GO:0070851
GeneOntologyMolecularFunctioncytokine receptor binding

ITCH PSG3 PSG4 SHC1 PPBP JAK3 ANGPT4 PSG8

6.14e-043241168GO:0005126
GeneOntologyMolecularFunctionfilamin binding

PSG3 PSG4 PSG8

6.25e-04291163GO:0031005
GeneOntologyMolecularFunctionToll-like receptor binding

PSG3 PSG4 PSG8

6.25e-04291163GO:0035325
GeneOntologyMolecularFunctionphosphatase binding

ANK1 PSG3 PSG4 SHC1 SHOC2 JAK3 PSG8

8.94e-042641167GO:0019902
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

PSG3 PSG4 PSG8

1.00e-03341163GO:0015125
GeneOntologyMolecularFunctionkinase binding

RASGRF1 PSG3 PSG4 PSG7 POTEF SHC1 CIT OPA1 POTEE ANGPT4 PSG8 DUSP10 POTEI POTEJ

1.48e-0396911614GO:0019900
GeneOntologyMolecularFunctionprotein kinase binding

RASGRF1 PSG3 PSG4 PSG7 POTEF SHC1 CIT POTEE ANGPT4 PSG8 DUSP10 POTEI POTEJ

1.68e-0387311613GO:0019901
GeneOntologyBiologicalProcessneuron projection development

PLXNA3 DIP2B RASGRF1 POTEF SHC1 BBS1 VPS54 SHOC2 CIT OPA1 POTEE FBXO38 STK11 ARSB TET1 VPS13A MACF1 KDR POTEI POTEJ RPL4 SOS1

2.47e-06128511622GO:0031175
GeneOntologyBiologicalProcesspositive regulation of vasculogenesis

PSG3 PSG4 KDR PSG8

9.25e-06241164GO:2001214
GeneOntologyBiologicalProcessneuron projection morphogenesis

PLXNA3 DIP2B POTEF VPS54 CIT OPA1 POTEE STK11 TET1 VPS13A MACF1 KDR POTEI POTEJ RPL4 SOS1

1.08e-0580211616GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

PLXNA3 DIP2B POTEF VPS54 CIT OPA1 POTEE STK11 TET1 VPS13A MACF1 KDR POTEI POTEJ RPL4 SOS1

1.40e-0581911616GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

PLXNA3 DIP2B POTEF VPS54 CIT OPA1 POTEE STK11 TET1 VPS13A MACF1 KDR POTEI POTEJ RPL4 SOS1

1.56e-0582611616GO:0048858
GeneOntologyBiologicalProcessneuron development

PLXNA3 DIP2B RASGRF1 POTEF SHC1 BBS1 VPS54 SHOC2 CIT OPA1 POTEE FBXO38 STK11 ARSB TET1 VPS13A MACF1 KDR POTEI POTEJ RPL4 SOS1

1.94e-05146311622GO:0048666
GeneOntologyBiologicalProcessregulation of vasculogenesis

PSG3 PSG4 KDR PSG8

2.02e-05291164GO:2001212
GeneOntologyBiologicalProcesspostsynaptic actin cytoskeleton organization

POTEF POTEE POTEI POTEJ

2.66e-05311164GO:0098974
GeneOntologyBiologicalProcessnegative regulation of platelet activation

PSG3 PSG4 PSG8 GP5

2.66e-05311164GO:0010544
GeneOntologyBiologicalProcesspyrimidine ribonucleotide catabolic process

UPB1 NT5C3A ENTPD4

2.77e-05111163GO:0009222
GeneOntologyBiologicalProcesscell morphogenesis

PLXNA3 DIP2B POTEF BBS1 VPS54 CIT OPA1 ADD1 POTEE STK11 FAT1 TET1 VPS13A MACF1 KDR POTEI POTEJ RPL4 SOS1

3.64e-05119411619GO:0000902
GeneOntologyBiologicalProcessnegative regulation of vascular permeability

PSG3 PSG4 ABCC8 PSG8

3.87e-05341164GO:0043116
GeneOntologyBiologicalProcesspostsynaptic cytoskeleton organization

POTEF POTEE POTEI POTEJ

4.35e-05351164GO:0099188
GeneOntologyBiologicalProcessresponse to peptide hormone

PSG3 PSG4 SHC1 SHOC2 OPA1 JAK3 STK11 FAT1 ABCC8 H2AZ1 PSG8 SOS1

4.46e-0553011612GO:0043434
GeneOntologyBiologicalProcesscellular response to peptide hormone stimulus

PSG3 PSG4 SHC1 SHOC2 OPA1 JAK3 FAT1 H2AZ1 PSG8 SOS1

5.90e-0538111610GO:0071375
GeneOntologyBiologicalProcessnegative regulation of brown fat cell proliferation

PSG3 PSG4 PSG8

6.03e-05141163GO:0070348
GeneOntologyBiologicalProcessregulation of brown fat cell proliferation

PSG3 PSG4 PSG8

7.51e-05151163GO:0070347
GeneOntologyBiologicalProcesspositive regulation of homophilic cell adhesion

PSG3 PSG4 PSG8

7.51e-05151163GO:1903387
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immune response to tumor cell

PSG3 PSG4 PSG8

7.51e-05151163GO:0002856
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

PSG3 PSG4 PSG8

7.51e-05151163GO:0002859
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

PLXNA3 DIP2B POTEF BBS1 CIT OPA1 POTEE STK11 TET1 MACF1 POTEI POTEJ RPL4 SOS1

7.97e-0574811614GO:0048667
GeneOntologyBiologicalProcessinsulin receptor internalization

PSG3 PSG4 PSG8

9.20e-05161163GO:0038016
GeneOntologyBiologicalProcessbrown fat cell proliferation

PSG3 PSG4 PSG8

1.11e-04171163GO:0070342
GeneOntologyBiologicalProcessinsulin catabolic process

PSG3 PSG4 PSG8

1.11e-04171163GO:1901143
GeneOntologyBiologicalProcessgranulocyte colony-stimulating factor signaling pathway

PSG3 PSG4 PSG8

1.11e-04171163GO:0038158
GeneOntologyBiologicalProcessanatomical structure homeostasis

PSG3 PSG4 BBS1 VPS54 ADD1 STK11 ABCC8 PSG8 MUC5AC

1.15e-043341169GO:0060249
GeneOntologyBiologicalProcesstissue homeostasis

PSG3 PSG4 BBS1 VPS54 ADD1 STK11 ABCC8 PSG8 MUC5AC

1.15e-043341169GO:0001894
GeneOntologyBiologicalProcesspyrimidine-containing compound catabolic process

UPB1 NT5C3A ENTPD4 TET1

1.29e-04461164GO:0072529
GeneOntologyBiologicalProcessregulation of homophilic cell adhesion

PSG3 PSG4 PSG8

1.33e-04181163GO:1903385
GeneOntologyBiologicalProcessbile acid and bile salt transport

PSG3 PSG4 PSG8 ABCC2

1.41e-04471164GO:0015721
GeneOntologyBiologicalProcesshemopoiesis

ITCH ANK1 PSG3 PSG4 ARL11 C17orf99 VPS54 OPA1 ADD1 JAK3 STK11 VPS13A KDR PSG8 ALAS2 DUSP10 SOS1 GP5

1.61e-04122311618GO:0030097
GeneOntologyBiologicalProcessregulation of immune response to tumor cell

PSG3 PSG4 FBXO38 PSG8

1.66e-04491164GO:0002837
GeneOntologyBiologicalProcessnegative regulation of cell development

PLXNA3 DIP2B PSG3 PSG4 CIT JAK3 ABCC8 PSG8 DUSP10

1.74e-043531169GO:0010721
GeneOntologyBiologicalProcessregulation of response to tumor cell

PSG3 PSG4 FBXO38 PSG8

1.79e-04501164GO:0002834
GeneOntologyBiologicalProcessnegative regulation of hepatocyte proliferation

PSG3 PSG4 PSG8

1.84e-04201163GO:2000346
GeneOntologyBiologicalProcessnegative regulation of fat cell proliferation

PSG3 PSG4 PSG8

2.14e-04211163GO:0070345
GeneOntologyBiologicalProcessnegative regulation of response to tumor cell

PSG3 PSG4 PSG8

2.14e-04211163GO:0002835
GeneOntologyBiologicalProcessnegative regulation of immune response to tumor cell

PSG3 PSG4 PSG8

2.14e-04211163GO:0002838
GeneOntologyBiologicalProcessresponse to hormone

PSG3 PSG4 SHC1 VPS54 SHOC2 OPA1 USP26 JAK3 STK11 FAT1 ARSB ABCC8 H2AZ1 PSG8 ABCC2 SOS1

2.40e-04104211616GO:0009725
GeneOntologyBiologicalProcessmulticellular organismal-level homeostasis

ANK1 PSG3 PSG4 BBS1 VPS54 ADD1 JAK3 STK11 ABCC8 VPS13A KDR PSG8 ALAS2 PLCL1 MUC5AC SOS1

2.43e-04104311616GO:0048871
GeneOntologyBiologicalProcessnegative regulation of granulocyte differentiation

PSG3 PSG4 PSG8

2.47e-04221163GO:0030853
GeneOntologyBiologicalProcessimmune response to tumor cell

PSG3 PSG4 FBXO38 PSG8

2.78e-04561164GO:0002418
GeneOntologyBiologicalProcesspyrimidine nucleotide catabolic process

UPB1 NT5C3A ENTPD4

2.83e-04231163GO:0006244
GeneOntologyBiologicalProcessnegative regulation of platelet aggregation

PSG3 PSG4 PSG8

2.83e-04231163GO:0090331
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity directed against tumor cell target

PSG3 PSG4 PSG8

2.83e-04231163GO:0002858
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immune response to tumor cell

PSG3 PSG4 PSG8

3.22e-04241163GO:0002855
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity directed against tumor cell target

PSG3 PSG4 PSG8

3.22e-04241163GO:0002420
GeneOntologyBiologicalProcesscommon myeloid progenitor cell proliferation

PSG3 PSG4 PSG8

3.64e-04251163GO:0035726
GeneOntologyBiologicalProcessnatural killer cell mediated immune response to tumor cell

PSG3 PSG4 PSG8

3.64e-04251163GO:0002423
GeneOntologyBiologicalProcesspositive regulation of Ras protein signal transduction

RASGRF1 SHOC2 SOS1

3.64e-04251163GO:0046579
GeneOntologyBiologicalProcessregulation of cell development

PLXNA3 DIP2B PSG3 PSG4 CIT OPA1 ADD1 JAK3 STK11 ABCC8 MACF1 KDR PSG8 DUSP10 RPL4 SOS1

4.16e-04109511616GO:0060284
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

TRPM4 NRIP1 PSG3 PSG4 SHC1 HTR3C VPS54 PPBP SHOC2 OPA1 ADD1 JAK3 FAT1 ABCC8 TET1 H2AZ1 PSG8 CD180 SOS1

4.53e-04145011619GO:1901701
GeneOntologyBiologicalProcessregulation of fat cell proliferation

PSG3 PSG4 PSG8

4.59e-04271163GO:0070344
GeneOntologyBiologicalProcessnegative regulation of homotypic cell-cell adhesion

PSG3 PSG4 PSG8

5.12e-04281163GO:0034111
GeneOntologyBiologicalProcessregulation of platelet activation

PSG3 PSG4 PSG8 GP5

5.23e-04661164GO:0010543
GeneOntologyBiologicalProcessregulation of endothelial cell differentiation

PSG3 PSG4 ADD1 PSG8

5.54e-04671164GO:0045601
GeneOntologyBiologicalProcesspost-Golgi vesicle-mediated transport

BBS1 VPS54 VPS13A MACF1 VPS29

5.66e-041191165GO:0006892
GeneOntologyBiologicalProcessnegative regulation of blood coagulation

PSG3 PSG4 PSG8 GP5

6.19e-04691164GO:0030195
GeneOntologyBiologicalProcessCMP catabolic process

UPB1 NT5C3A

6.46e-0471162GO:0006248
GeneOntologyBiologicalProcessdTMP catabolic process

UPB1 NT5C3A

6.46e-0471162GO:0046074
GeneOntologyBiologicalProcessdUMP catabolic process

UPB1 NT5C3A

6.46e-0471162GO:0046079
GeneOntologyBiologicalProcessUMP catabolic process

UPB1 NT5C3A

6.46e-0471162GO:0046050
GeneOntologyBiologicalProcessnegative regulation of hemostasis

PSG3 PSG4 PSG8 GP5

6.54e-04701164GO:1900047
GeneOntologyBiologicalProcessregulation of neurogenesis

PLXNA3 DIP2B CIT OPA1 STK11 ABCC8 MACF1 KDR DUSP10 RPL4

6.62e-0451511610GO:0050767
GeneOntologyBiologicalProcessregulation of vascular permeability

PSG3 PSG4 ABCC8 PSG8

6.90e-04711164GO:0043114
GeneOntologyBiologicalProcessresponse to tumor cell

PSG3 PSG4 FBXO38 PSG8

6.90e-04711164GO:0002347
GeneOntologyBiologicalProcessregulation of cell growth

PLXNA3 DIP2B ITCH PSG3 JADE3 PSG4 STK11 MACF1 PSG8 RPL4

7.02e-0451911610GO:0001558
GeneOntologyBiologicalProcessresponse to insulin

PSG3 PSG4 SHC1 OPA1 ABCC8 H2AZ1 PSG8 SOS1

7.08e-043421168GO:0032868
GeneOntologyBiologicalProcessnegative regulation of coagulation

PSG3 PSG4 PSG8 GP5

7.28e-04721164GO:0050819
GeneOntologyBiologicalProcessregulation of epithelial cell migration

PSG3 PSG4 ARSB ANGPT4 MACF1 KDR PSG8 DUSP10

7.35e-043441168GO:0010632
GeneOntologyBiologicalProcessvascular process in circulatory system

TRPM4 PSG3 PSG4 SHC1 ABCC8 KDR PSG8 ABCC2

7.35e-043441168GO:0003018
GeneOntologyBiologicalProcessepithelial cell migration

PSG3 PSG4 ARSB ANGPT4 LPXN MACF1 KDR PSG8 DUSP10

7.55e-044321169GO:0010631
GeneOntologyBiologicalProcessnegative regulation of bone resorption

PSG3 PSG4 PSG8

7.63e-04321163GO:0045779
GeneOntologyBiologicalProcessfat cell proliferation

PSG3 PSG4 PSG8

7.63e-04321163GO:0070341
GeneOntologyBiologicalProcessregulation of blood vessel remodeling

PSG3 PSG4 PSG8

7.63e-04321163GO:0060312
GeneOntologyBiologicalProcessepithelium migration

PSG3 PSG4 ARSB ANGPT4 LPXN MACF1 KDR PSG8 DUSP10

7.93e-044351169GO:0090132
GeneOntologyBiologicalProcesscellular response to hormone stimulus

PSG3 PSG4 SHC1 VPS54 SHOC2 OPA1 USP26 JAK3 FAT1 H2AZ1 PSG8 SOS1

8.11e-0472711612GO:0032870
GeneOntologyBiologicalProcessregulation of granulocyte differentiation

PSG3 PSG4 PSG8

8.36e-04331163GO:0030852
GeneOntologyBiologicalProcessnegative regulation of feeding behavior

PSG3 PSG4 PSG8

8.36e-04331163GO:2000252
GeneOntologyBiologicalProcessdCMP catabolic process

UPB1 NT5C3A

8.59e-0481162GO:0006249
GeneOntologyBiologicalProcessdUMP metabolic process

UPB1 NT5C3A

8.59e-0481162GO:0046078
GeneOntologyBiologicalProcessdCMP metabolic process

UPB1 NT5C3A

8.59e-0481162GO:0046063
GeneOntologyBiologicalProcesspyrimidine ribonucleoside monophosphate catabolic process

UPB1 NT5C3A

8.59e-0481162GO:0009175
GeneOntologyBiologicalProcesscellular response to insulin stimulus

PSG3 PSG4 SHC1 OPA1 H2AZ1 PSG8 SOS1

8.63e-042711167GO:0032869
GeneOntologyBiologicalProcesstissue migration

PSG3 PSG4 ARSB ANGPT4 LPXN MACF1 KDR PSG8 DUSP10

8.73e-044411169GO:0090130
GeneOntologyBiologicalProcesspyrimidine ribonucleotide metabolic process

UPB1 NT5C3A ENTPD4

9.13e-04341163GO:0009218
GeneOntologyBiologicalProcessnegative regulation of bone remodeling

PSG3 PSG4 PSG8

9.13e-04341163GO:0046851
GeneOntologyBiologicalProcessinsulin metabolic process

PSG3 PSG4 PSG8

9.95e-04351163GO:1901142
GeneOntologyBiologicalProcesscellular response to nitrogen compound

TRPM4 PSG3 PSG4 SHC1 HTR3C SHOC2 OPA1 JAK3 FAT1 H2AZ1 PSG8 SOS1

1.09e-0375211612GO:1901699
GeneOntologyBiologicalProcessregulation of T cell activation

ITCH PSG3 PSG4 OPA1 JAK3 FBXO38 PSG8 DUSP10 SOS1

1.14e-034581169GO:0050863
GeneOntologyBiologicalProcessepidermal growth factor receptor signaling pathway

PSG3 PSG4 SHC1 PSG8 SOS1

1.14e-031391165GO:0007173
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

PLXNA3 DIP2B PSG3 PSG4 SHC1 CIT OPA1 ADD1 STK11 ABCC8 ANGPT4 MACF1 KDR PSG8 RPL4

1.17e-03109011615GO:0022603
GeneOntologyBiologicalProcessregulation of hepatocyte proliferation

PSG3 PSG4 PSG8

1.27e-03381163GO:2000345
GeneOntologyBiologicalProcessaxonogenesis

PLXNA3 DIP2B POTEF POTEE STK11 MACF1 POTEI POTEJ RPL4 SOS1

1.35e-0356611610GO:0007409
GeneOntologyBiologicalProcessnegative regulation of fatty acid biosynthetic process

PSG3 PSG4 PSG8

1.37e-03391163GO:0045717
GeneOntologyBiologicalProcesspositive regulation of rRNA processing

DIMT1 WDR75

1.37e-03101162GO:2000234
GeneOntologyBiologicalProcesspyrimidine nucleoside monophosphate catabolic process

UPB1 NT5C3A

1.37e-03101162GO:0009131
GeneOntologyBiologicalProcesspyrimidine deoxyribonucleoside monophosphate catabolic process

UPB1 NT5C3A

1.37e-03101162GO:0009178
GeneOntologyBiologicalProcessregulation of epidermal growth factor receptor signaling pathway

PSG3 PSG4 PSG8 SOS1

1.41e-03861164GO:0042058
GeneOntologyBiologicalProcessregulation of growth

PLXNA3 DIP2B ITCH PSG3 JADE3 PSG4 VPS54 STK11 MACF1 PSG8 DUSP10 RPL4

1.43e-0377711612GO:0040008
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

POTEF POTEE POTEI POTEJ

2.77e-05321154GO:0035267
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

POTEF POTEE POTEI POTEJ

2.77e-05321154GO:0043189
GeneOntologyCellularComponenttransforming growth factor beta ligand-receptor complex

PSG3 PSG4 PSG8

8.62e-05161153GO:0070021
GeneOntologyCellularComponentH4 histone acetyltransferase complex

POTEF POTEE POTEI POTEJ

1.09e-04451154GO:1902562
GeneOntologyCellularComponenthistone acetyltransferase complex

JADE3 POTEF POTEE POTEI POTEJ

1.72e-04941155GO:0000123
GeneOntologyCellularComponentprotein acetyltransferase complex

JADE3 POTEF POTEE POTEI POTEJ

2.75e-041041155GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

JADE3 POTEF POTEE POTEI POTEJ

3.42e-041091155GO:1902493
GeneOntologyCellularComponentanchoring junction

PSG3 PSG4 SHC1 ADD1 PGM5 SLC3A2 FAT1 HMCN1 LPXN KDR PSG8 CGNL1 ABCC2 RPL4

9.42e-0497611514GO:0070161
GeneOntologyCellularComponentadherens junction

PSG3 PSG4 ADD1 PGM5 HMCN1 PSG8

1.14e-032121156GO:0005912
GeneOntologyCellularComponentactin cytoskeleton

POTEF CIT ADD1 PGM5 POTEE LPXN MACF1 CGNL1 POTEI POTEJ

1.31e-0357611510GO:0015629
DomainAnkyrin_rpt

TRPM4 SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

7.19e-0726211611IPR002110
DomainAnk_2

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

9.35e-0721511610PF12796
DomainAnk

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

1.59e-0622811610PF00023
DomainActin_CS

POTEF POTEE POTEI POTEJ

2.43e-06161164IPR004001
DomainACTINS_2

POTEF POTEE POTEI POTEJ

3.16e-06171164PS00432
Domain-

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

3.38e-06248116101.25.40.20
DomainANK

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

3.76e-0625111610SM00248
DomainANK_REPEAT

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

4.04e-0625311610PS50088
DomainActin/actin-like_CS

POTEF POTEE POTEI POTEJ

4.04e-06181164IPR020902
DomainAnkyrin_rpt-contain_dom

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

4.18e-0625411610IPR020683
DomainANK_REP_REGION

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

4.18e-0625411610PS50297
DomainACTINS_ACT_LIKE

POTEF POTEE POTEI POTEJ

5.09e-06191164PS01132
DomainCCDC74

CCDC74B CCDC74A

3.82e-0521162IPR033226
DomainCCDC74_C

CCDC74B CCDC74A

3.82e-0521162IPR029422
DomainCCDC74_C

CCDC74B CCDC74A

3.82e-0521162PF14917
DomainActin

POTEF POTEE POTEI POTEJ

3.90e-05311164IPR004000
DomainActin

POTEF POTEE POTEI POTEJ

3.90e-05311164PF00022
DomainACTIN

POTEF POTEE POTEI POTEJ

3.90e-05311164SM00268
DomainIGc2

IGFN1 PSG3 PSG4 PSG7 HMCN1 KDR PSG8

6.66e-042351167SM00408
DomainIg_sub2

IGFN1 PSG3 PSG4 PSG7 HMCN1 KDR PSG8

6.66e-042351167IPR003598
DomainIg_2

PSG3 PSG4 PSG7 PSG8

1.11e-03731164PF13895
Domainig

PSG3 PSG4 PSG7 HMCN1 KDR PSG8

1.20e-031901166PF00047
DomainImmunoglobulin

PSG3 PSG4 PSG7 HMCN1 KDR PSG8

1.20e-031901166IPR013151
DomainCalx_beta

FRAS1 FREM1

1.34e-0391162IPR003644
DomainCalx-beta

FRAS1 FREM1

1.34e-0391162PF03160
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

PSG3 PSG4 PSG7 SHC1 SLC3A2 ANGPT4 PSG8 SOS1

1.99e-05194848M16312
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

PSG3 PSG4 SHC1 SLC3A2 ANGPT4 PSG8 SOS1

4.28e-05158847MM14812
PathwayREACTOME_INTERLEUKIN_15_SIGNALING

SHC1 JAK3 SOS1

7.09e-0514843M27858
PathwayPID_TCPTP_PATHWAY

SHC1 JAK3 KDR SOS1

1.10e-0442844M91
PathwayWP_EGFR1_SIGNALING_PATHWAY

ITCH PSG3 PSG4 SHC1 SHOC2 PSG8 SOS1

1.28e-04188847MM15828
PathwayREACTOME_TIE2_SIGNALING

SHC1 ANGPT4 SOS1

1.31e-0417843MM14836
PathwayREACTOME_TIE2_SIGNALING

SHC1 ANGPT4 SOS1

1.56e-0418843M11932
PathwayBIOCARTA_IL6_PATHWAY

SHC1 JAK3 SOS1

2.51e-0421843M5489
PathwayBIOCARTA_IL2_PATHWAY

SHC1 JAK3 SOS1

2.90e-0422843M7747
PathwayBIOCARTA_IL6_PATHWAY

SHC1 JAK3 SOS1

2.90e-0422843MM1415
PathwayBIOCARTA_IL2_PATHWAY

SHC1 JAK3 SOS1

3.32e-0423843MM1411
PathwayPID_SHP2_PATHWAY

SHC1 JAK3 KDR SOS1

3.64e-0457844M100
PathwayREACTOME_SHC_RELATED_EVENTS_TRIGGERED_BY_IGF1R

SHC1 SOS1

5.18e-046842MM14887
PathwaySIG_IL4RECEPTOR_IN_B_LYPHOCYTES

SHC1 JAK3 SOS1

5.38e-0427843M1718
PathwayREACTOME_INTERLEUKIN_RECEPTOR_SHC_SIGNALING

SHC1 JAK3 SOS1

5.38e-0427843M921
Pubmed

Identification of a novel actin isoform in hepatocellular carcinoma.

POTEF POTEG POTEE POTEM POTEI POTEJ

6.55e-1215118616824795
Pubmed

Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.

POTEE POTEM POTEI POTEA POTEJ

5.14e-119118516364570
Pubmed

Evolution and expression of chimeric POTE-actin genes in the human genome.

POTEF POTEE POTEJ

3.81e-083118317101985
Pubmed

Activation of CEA-CAM-1-mediated cell adhesion via CD98: involvement of PKCdelta.

PSG3 PSG4 SLC3A2 PSG8

1.67e-0715118414527684
Pubmed

CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation.

PSG3 PSG4 SHC1 PSG8

1.67e-0715118415467833
Pubmed

Shc and CEACAM1 interact to regulate the mitogenic action of insulin.

PSG3 PSG4 SHC1 PSG8

2.22e-0716118411694516
Pubmed

Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region.

PSG3 PSG4 PSG7 PSG8

2.90e-071711847851895
Pubmed

16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells.

SHC1 KDR SOS1

3.79e-075118310319320
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PLXNA3 H2AZ2 POTEF SLC3A2 KRT73 POTEE STK11 C2CD3 WDR75 VPS13A H2AZ1 MACF1 KDR ALAS2 MPHOSPH10 ABCC2 POTEI POTEJ RPL4

4.01e-0714421181935575683
Pubmed

Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.

POTEG POTEE POTEA

1.32e-067118315276201
Pubmed

The Vertebrate Genome Annotation browser 10 years on.

POTEF POTEG POTEE POTEM POTEI POTEA POTEJ

1.49e-06163118724316575
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

H2AZ2 POTEF POTEE TSR1 POTEI POTEJ RPL4 HDLBP

4.28e-06271118832433965
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 TRPM4 FRAS1 RTTN KIAA0319L SHC1 KDM3B CIT DUS1L PPP1R26 JAK3 FAT1 C2CD3 PSME4 ZNF426

5.27e-0611051181535748872
Pubmed

A mouse carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule.

PSG3 PSG4 PSG8

1.06e-051311831985902
Pubmed

CEACAM1+ myeloid cells control angiogenesis in inflammation.

PSG3 PSG4 PSG8

1.06e-0513118319273835
Pubmed

Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.

PSG3 PSG4 PSG8

1.06e-0513118316638824
Pubmed

Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1.

PSG3 PSG4 PSG8

1.06e-0513118320044046
Pubmed

Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.

PSG3 PSG4 PSG8

1.06e-0513118332150576
Pubmed

Mouse hepatitis virus type 4 (JHM strains). induced fatal central nervous system disease. I. genetic control and murine neuron as the susceptible site of disease.

PSG3 PSG4 PSG8

1.06e-051311836265583
Pubmed

Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1.

PSG3 PSG4 PSG8

1.06e-0513118334440862
Pubmed

CEACAM1 is a potent regulator of B cell receptor complex-induced activation.

PSG3 PSG4 PSG8

1.06e-0513118312832451
Pubmed

CEACAM1 confers resistance toward oxygen-induced vessel damage in a mouse model of retinopathy of prematurity.

PSG3 PSG4 PSG8

1.06e-0513118325406283
Pubmed

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor.

PSG3 PSG4 PSG8

1.06e-0513118321670291
Pubmed

Investigations on the usefulness of CEACAMs as potential imaging targets for molecular imaging purposes.

PSG3 PSG4 PSG8

1.06e-0513118322162753
Pubmed

A mouse analogue of the human carcinoembryonic antigen.

PSG3 PSG4 PSG8

1.06e-051311832702644
Pubmed

Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59.

PSG3 PSG4 PSG8

1.06e-051311838380065
Pubmed

The receptor for mouse hepatitis virus in the resistant mouse strain SJL is functional: implications for the requirement of a second factor for viral infection.

PSG3 PSG4 PSG8

1.06e-051311831279194
Pubmed

Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice.

PSG3 PSG4 PSG8

1.06e-0513118325724769
Pubmed

High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion.

PSG3 PSG4 PSG8

1.06e-0513118326374765
Pubmed

CEACAM1 deficiency delays important wound healing processes.

PSG3 PSG4 PSG8

1.06e-0513118322092845
Pubmed

Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function.

PSG3 PSG4 PSG8

1.06e-0513118311801635
Pubmed

Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice.

PSG3 PSG4 PSG8

1.06e-0513118328913658
Pubmed

Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms.

PSG3 PSG4 PSG8

1.06e-051311838500759
Pubmed

Mouse susceptibility to mouse hepatitis virus infection is linked to viral receptor genotype.

PSG3 PSG4 PSG8

1.06e-051311839343248
Pubmed

Ceacam1 deletion causes vascular alterations in large vessels.

PSG3 PSG4 PSG8

1.06e-0513118323800882
Pubmed

Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture.

PSG3 PSG4 PSG8

1.06e-0513118319285068
Pubmed

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.

PSG3 PSG4 PSG8

1.06e-0513118321760897
Pubmed

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.

PSG3 PSG4 PSG8

1.06e-051311831719235
Pubmed

Mouse hepatitis virus utilizes two carcinoembryonic antigens as alternative receptors.

PSG3 PSG4 PSG8

1.06e-051311831326665
Pubmed

Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation.

PSG3 PSG4 PSG8

1.06e-0513118339168268
Pubmed

The expression of mouse biliary glycoprotein, a carcinoembryonic antigen-related gene, is down-regulated in malignant mouse tissues.

PSG3 PSG4 PSG8

1.06e-051311838402684
Pubmed

Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.

PSG3 PSG4 PSG8

1.06e-0513118316619040
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice.

PSG3 PSG4 PSG8

1.06e-0513118329377208
Pubmed

Expression of MHV-A59 receptor glycoproteins in susceptible and resistant strains of mice.

PSG3 PSG4 PSG8

1.06e-051311838209741
Pubmed

Leptin Resistance Contributes to Obesity in Mice with Null Mutation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1.

PSG3 PSG4 PSG8

1.06e-0513118327002145
Pubmed

Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.

PSG3 PSG4 PSG8

1.06e-0513118321949477
Pubmed

Differential effects of prenatal stress on metabolic programming in diet-induced obese and dietary-resistant rats.

PSG3 PSG4 PSG8

1.06e-0513118326219866
Pubmed

Spatiotemporal expression of murine carcinoembryonic antigen (CEA) gene family members during mouse embryogenesis.

PSG3 PSG4 PSG8

1.06e-051311832133556
Pubmed

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis.

PSG3 PSG4 PSG8

1.06e-0513118332521208
Pubmed

Targeted disruption of carcinoembryonic antigen-related cell adhesion molecule 1 promotes diet-induced hepatic steatosis and insulin resistance.

PSG3 PSG4 PSG8

1.06e-0513118319406938
Pubmed

Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1.

PSG3 PSG4 PSG8

1.06e-0513118319621080
Pubmed

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

PSG3 PSG4 PSG8

1.06e-0513118329967450
Pubmed

Expression of newly identified secretory CEACAM1(a) isoforms in the intestinal epithelium.

PSG3 PSG4 PSG8

1.06e-0513118319358828
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo.

PSG3 PSG4 PSG8

1.06e-0513118316680193
Pubmed

The mouse biliary glycoprotein gene (Bgp): partial nucleotide sequence, expression, and chromosomal assignment.

PSG3 PSG4 PSG8

1.06e-051311831653760
Pubmed

Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1.

PSG3 PSG4 PSG8

1.06e-0513118334058224
Pubmed

Down-regulation of Bgp1(a) viral receptor by interferon-gamma is related to the antiviral state and resistance to mouse hepatitis virus 3 infection.

PSG3 PSG4 PSG8

1.06e-0513118310964771
Pubmed

Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma.

PSG3 PSG4 PSG8

1.06e-0513118332169849
Pubmed

Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.

PSG3 PSG4 PSG8

1.06e-0513118322469976
Pubmed

CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.

PSG3 PSG4 PSG8

1.06e-0513118321532628
Pubmed

Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.

PSG3 PSG4 PSG8

1.06e-0513118328035001
Pubmed

Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.

PSG3 PSG4 PSG8

1.06e-0513118315316023
Pubmed

In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.

PSG3 PSG4 PSG8

1.06e-0513118323935487
Pubmed

Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59.

PSG3 PSG4 PSG8

1.06e-0513118315331748
Pubmed

Organ tropism of murine coronavirus does not correlate with the expression levels of the membrane-anchored or secreted isoforms of the carcinoembryonic antigen-related cell adhesion molecule 1 receptor.

PSG3 PSG4 PSG8

1.06e-0513118322673933
Pubmed

Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1.

PSG3 PSG4 PSG8

1.06e-0513118322406619
Pubmed

Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene.

PSG3 PSG4 PSG8

1.06e-051311837628460
Pubmed

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance.

PSG3 PSG4 PSG8

1.06e-0513118325972571
Pubmed

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo.

PSG3 PSG4 PSG8

1.06e-0513118319008452
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

PSG3 PSG4 PSG8

1.06e-0513118318544705
Pubmed

Expression of the mouse hepatitis virus receptor by central nervous system microglia.

PSG3 PSG4 PSG8

1.06e-0513118315220458
Pubmed

Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.

PSG3 PSG4 PSG8

1.06e-0513118318843289
Pubmed

Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59.

PSG3 PSG4 PSG8

1.06e-0513118315207636
Pubmed

CEACAM1: a key regulator of vascular permeability.

PSG3 PSG4 PSG8

1.06e-0513118321081647
Pubmed

Pregnancy-specific glycoprotein (PSG) in baboon (Papio hamadryas): family size, domain structure, and prediction of a functional region in primate PSGs.

PSG3 PSG4 PSG8

1.06e-0513118311133662
Pubmed

Targeted disruption of the Ceacam1 (MHVR) gene leads to reduced susceptibility of mice to mouse hepatitis virus infection.

PSG3 PSG4 PSG8

1.06e-0513118311483763
Pubmed

Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice.

PSG3 PSG4 PSG8

1.06e-051311832164599
Pubmed

Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene.

PSG3 PSG4 PSG8

1.06e-0513118329396368
Pubmed

The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- Mice.

PSG3 PSG4 PSG8

1.06e-0513118318003729
Pubmed

Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue.

PSG3 PSG4 PSG8

1.06e-0513118326284027
Pubmed

CEACAM1 specifically suppresses B cell receptor signaling-mediated activation.

PSG3 PSG4 PSG8

1.06e-0513118333352461
Pubmed

Loss of CEACAM1 in hepatocytes causes hepatic fibrosis.

PSG3 PSG4 PSG8

1.06e-0513118338381498
Pubmed

Murine coronavirus receptors are differentially expressed in the central nervous system and play virus strain-dependent roles in neuronal spread.

PSG3 PSG4 PSG8

1.06e-0513118320739537
Pubmed

mmCGM1a: a mouse carcinoembryonic antigen gene family member, generated by alternative splicing, functions as an adhesion molecule.

PSG3 PSG4 PSG8

1.06e-051311831633107
Pubmed

The role of CEA-related cell adhesion molecule-1 (CEACAM1) in vascular homeostasis.

PSG3 PSG4 PSG8

1.06e-0513118327695943
Pubmed

Generation of human CEACAM1 transgenic mice and binding of Neisseria Opa protein to their neutrophils.

PSG3 PSG4 PSG8

1.06e-0513118320404914
Pubmed

Loss of CEACAM1, a Tumor-Associated Factor, Attenuates Post-infarction Cardiac Remodeling by Inhibiting Apoptosis.

PSG3 PSG4 PSG8

1.06e-0513118326911181
Pubmed

Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury.

PSG3 PSG4 PSG8

1.06e-0513118332027621
Pubmed

Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis.

PSG3 PSG4 PSG8

1.06e-0513118330664851
Pubmed

Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis.

PSG3 PSG4 PSG8

1.06e-0513118327777319
Pubmed

Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice.

PSG3 PSG4 PSG8

1.06e-0513118318848945
Pubmed

Variants in genes encoding the SUR1-TRPM4 non-selective cation channel and sudden infant death syndrome (SIDS): potentially increased risk for cerebral edema.

TRPM4 ABCC8

1.14e-052118235474489
Pubmed

The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes.

SHC1 SOS1

1.14e-05211828631299
Pubmed

The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.

TRPM4 ABCC8

1.14e-052118227246103
Pubmed

Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca2+-induced mucin secretion from goblet cells.

TRPM4 MUC5AC

1.14e-052118230482841
Pubmed

A primate-specific POTE-actin fusion protein plays a role in apoptosis.

POTEF POTEE

1.14e-052118219669888
Pubmed

Expression of the pregnancy-specific beta 1-glycoprotein genes in human testis.

PSG3 PSG8

1.14e-05211822302228
Pubmed

Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.

TRPM4 ABCC8

1.14e-052118234309670
Pubmed

Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.

TRPM4 ABCC8

1.14e-052118226172285
Pubmed

Cells Lacking PA200 Adapt to Mitochondrial Dysfunction by Enhancing Glycolysis via Distinct Opa1 Processing.

OPA1 PSME4

1.14e-052118233562813
InteractionPSG4 interactions

PSG3 PSG4 PSG8

1.05e-0581173int:PSG4
InteractionPOTEJ interactions

CIT POTEE POTEI POTEJ HDLBP

1.26e-05521175int:POTEJ
Cytoband2q21.1

CCDC74B POTEF POTEE CCDC74A POTEI POTEJ

9.20e-095811862q21.1
CytobandEnsembl 112 genes in cytogenetic band chr2q21

CCDC74B POTEF POTEE CCDC74A POTEI POTEJ

2.79e-061511186chr2q21
Cytoband8p11.1

ANK1 POTEA

3.92e-05411828p11.1
Cytoband19q13.2

PSG3 PSG4 PSG7 PSG8

8.78e-04164118419q13.2
Cytoband16q22.2

PKD1L3 HYDIN

1.46e-0322118216q22.2
Cytoband12q24

CIT VPS29

1.89e-0325118212q24
Cytoband2q33

ADAM23 PLCL1

2.54e-032911822q33
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEF POTEG POTEE POTEM POTEI POTEA POTEJ

4.26e-1413807685
GeneFamilyAnkyrin repeat domain containing

SLF1 ANK1 POTEF POTEG ANKRD6 POTEE POTEM POTEI POTEA POTEJ

1.11e-072428010403
GeneFamilyCD molecules|V-set domain containing|Pregnancy specific glycoproteins

PSG3 PSG4 PSG7 PSG8

1.15e-07118041315
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

VPS54 PPP1R26 PLCL1 MPHOSPH10 HYDIN

1.25e-03181805694
GeneFamilyATP binding cassette subfamily C

ABCC8 ABCC2

1.46e-0313802807
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_B

ADAM23 CNOT10 POTEF POTEG ANKRD6 SHOC2 SLC3A2 YARS2 CDC7 POTEE PSME4 POTEM POTEI POTEA POTEJ CD180

7.59e-0958411716MM1080
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IGFN1 ANK1 FREM1 FAT1 HMCN1 PIK3C2G HYDIN

3.35e-0818411882cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IGFN1 ANK1 FREM1 FAT1 HMCN1 PIK3C2G HYDIN

3.35e-081841188ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 IGFN1 ANK1 FREM1 FAT1 HMCN1 PIK3C2G HYDIN

3.35e-0818411882b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellTCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11|TCGA-Brain / Sample_Type by Project: Shred V9

POTEF POTEG POTEE POTEI POTEJ

7.09e-07631185d7dc1356a60cb527fe668328d5375f352239d911
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IQSEC3 C17orf99 POTEG FAT1 POTEM POTEJ

1.70e-06136118627a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IQSEC3 C17orf99 POTEG FAT1 POTEM POTEJ

1.70e-06136118688b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

ANK1 C17orf99 NT5C3A BBS1 ALAS2 GP5

3.37e-061531186654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

ANK1 C17orf99 NT5C3A BBS1 ALAS2 GP5

3.37e-061531186105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9|TCGA-Breast / Sample_Type by Project: Shred V9

POTEF POTEE POTEM POTEI POTEJ

4.19e-0690118596e836c7a1df279ac812b7c3aa75e6b81b614244
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

JADE3 HEATR5A FBXO38 HMCN1 SOS1 GP5

1.03e-05186118603db813598b67b1e08f759758a1c2023396921fa
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SHC1 PKD1L3 PGM5 MACF1 KDR LRRC15

1.03e-05186118620340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 ADAM23 RTTN FREM1 CGNL1 HYDIN

1.10e-051881186b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC74B C17orf99 ENO4 CCDC74A MUC5AC HYDIN

1.35e-051951186e525b69145059b66417589601f7109af63730f3a
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANK1 C17orf99 NT5C3A ANKRD6 PPBP ALAS2

1.52e-0519911866c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANK1 C17orf99 NT5C3A ANKRD6 PPBP ALAS2

1.52e-051991186284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Dpy19l1_(Neuron.Gad1Gad2.Synpr-Dpy19l1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NOXRED1 PPBP FREM1 KRT73

3.61e-057011841d06fd0e20f4b3ea71a83c87736236f5c8d39f65
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Dpy19l1_(Neuron.Gad1Gad2.Synpr-Dpy19l1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NOXRED1 PPBP FREM1 KRT73

3.61e-05701184e446f52534a1e8291dbb0973c6bc5094a3ebc96b
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 HMCN1 TET1 DUSP10 ABCC2

3.71e-05141118531e0984f09983e83a814424f74c871c1c5a3a789
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FRAS1 HMCN1 TET1 DUSP10 ABCC2

3.71e-051411185d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 USP26 NWD2 ABCC2 HYDIN

4.24e-05145118596712c68ab759d7ade0d912581a1a7c25dc6def8
DiseasecD177 antigen measurement

PSG4 PSG7 PSG8

3.54e-05181063EFO_0021866
DiseaseFraser syndrome (implicated_via_orthology)

FRAS1 FREM1

7.63e-0541062DOID:0090001 (implicated_via_orthology)
Diseasevisual epilepsy (implicated_via_orthology)

KDM3B CIT ABCC2

2.49e-04341063DOID:11832 (implicated_via_orthology)
Diseasebilirubin metabolic disorder (biomarker_via_orthology)

ALAS2 ABCC2

2.65e-0471062DOID:2741 (biomarker_via_orthology)
DiseaseUnilateral agenesis of kidney

FRAS1 FREM1

3.53e-0481062C0266294
DiseaseTurner Syndrome, Male

SHOC2 SOS1

6.88e-04111062C0041409
DiseaseFemale Pseudo-Turner Syndrome

SHOC2 SOS1

6.88e-04111062C1527404
DiseaseNoonan Syndrome 1

SHOC2 SOS1

6.88e-04111062C4551602
Diseasechronic lymphocytic leukemia

FREM1 ARSB NDUFAF7 HDLBP

9.10e-041191064EFO_0000095
Diseaserhinitis (biomarker_via_orthology)

OPA1 MUC5AC

9.72e-04131062DOID:4483 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

HTR3C ERI2 KRT73 STK11 FAT1 ABCC8 VPS13A KDR ABCC2

9.80e-047021069C0009402
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

DIP2B ITCH PKD1L3

1.09e-03561063EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseasefibrinogen measurement, factor VII measurement

DIP2B PKD1L3 HDLBP

1.20e-03581063EFO_0004619, EFO_0004623
DiseaseRASopathy

SHOC2 SOS1

1.30e-03151062cv:C5555857
Diseaselung non-small cell carcinoma (is_implicated_in)

SLC3A2 FAT1 KDR ABCC2

1.62e-031391064DOID:3908 (is_implicated_in)
Diseaseascending aortic diameter

DCDC1 HMCN1 ABCC8 HYDIN

1.66e-031401064EFO_0021787
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

SHOC2 SOS1

2.10e-03191062C3501846
DiseaseCostello syndrome (disorder)

SHOC2 SOS1

2.10e-03191062C0587248
Diseasehydrocephalus (implicated_via_orthology)

ADD1 HYDIN

2.10e-03191062DOID:10908 (implicated_via_orthology)
DiseaseNoonan syndrome-like disorder with loose anagen hair

SHOC2 SOS1

2.10e-03191062C1843181
DiseaseCardio-facio-cutaneous syndrome

SHOC2 SOS1

2.10e-03191062C1275081
Diseaseresponse to methotrexate, neurotoxicity

MACF1 PLCL1

2.10e-03191062EFO_0011057, GO_0031427
Diseasehaptoglobin measurement

PKD1L3 HYDIN

2.57e-03211062EFO_0004640
DiseasePrimary microcephaly

RTTN CIT

2.82e-03221062C0431350
DiseaseLEOPARD Syndrome

SHOC2 SOS1

2.82e-03221062C0175704
Diseaseresponse to clopidogrel, cardiovascular event measurement

FREM1 LIPM

3.08e-03231062EFO_0006919, GO_1903493
DiseaseNoonan Syndrome

SHOC2 SOS1

3.35e-03241062C0028326

Protein segments in the cluster

PeptideGeneStartEntry
QGHTKNLLRPTKLNL

USP26

766

Q9BXU7
SHGLLVQQALPKAKL

NT5C3A

156

Q9H0P0
SGVKHKGLIEIPNLS

AHSA2P

96

Q719I0
VLGKHPLLSGGTKRN

ERI2

521

A8K979
KSTGRPHIIQKTLAG

ADAM23

241

O75077
LLDHGAPIQAKTKNG

ANK1

291

P16157
IPHIHKSLIGKKGQQ

H2AZ2

111

Q71UI9
LLTVHGRTKEQKGPL

DUS1L

171

Q6P1R4
QKGNKGLGLTLTHLP

HTR3C

366

Q8WXA8
LNGPKSLKHLFLIQT

CD180

121

Q99467
LLHNSKLDKVPGVQG

CCDC74A

211

Q96AQ1
LLHNSKLDKVPGVQG

CCDC74B

211

Q96LY2
LSGISLQKKLQHVPG

CBWD5

251

Q5RIA9
LNVLKNSLTHVPGIG

CIT

1616

O14578
NSPVQLAGLKLLGHL

ARMCX5

406

Q6P1M9
KGILPTTIDKKHQNG

ATXN7L1

261

Q9ULK2
NKGHLPVVQILLKAG

ANKRD6

51

Q9Y2G4
KGIGTLHLKPTANQK

NUP50

376

Q9UKX7
IVLSTLPNKHGILQK

NWD2

541

Q9ULI1
KGLPHGNVSARKVLL

JAK3

641

P52333
RHSGLIGPLKENTIK

PIK3C2G

981

O75747
HAIKGLLTGPSQLKI

PGM5

211

Q15124
KLKGHQLVETLPTVG

ARL11

31

Q969Q4
HFQIGPLGEISLKKQ

FAT1

2126

Q14517
ESKNKHGLTPLLLGV

POTEF

266

A5A3E0
KSNIGHLCKLGPQLQ

DCDC1

451

M0R2J8
KHGNLEQISIKGPIR

FRAS1

2131

Q86XX4
SKLKLPNNGRIHVGK

MAGEB5

111

Q9BZ81
PGGIHQVTINKSLLA

KRT73

101

Q86Y46
KKTGSRPVVLLQHGL

LIPM

86

Q5VYY2
GKHSQILKLSKLTPG

KIAA0319L

361

Q8IZA0
LSGISLQKKLQHVPG

CBWD2

251

Q8IUF1
LSGISLQKKLQHVPG

CBWD1

251

Q9BRT8
PLVLKGGLSSFKQNH

DUSP10

266

Q9Y6W6
GSHVVLKGKNLIPAA

PLXNA3

1141

P51805
HALGPVKLSQKELLG

KIF22

381

Q14807
TLLHSPSQVGLLKNG

FREM1

1631

Q5H8C1
KTPLGGIHISQTKQL

DIP2B

906

Q9P265
QGQPVLVSGVHKKLK

KDM3B

1411

Q7LBC6
TVLQLLLGNPNKGKS

NRIP1

711

P48552
KILENGRIHGSPLQK

MPHOSPH10

51

O00566
QKPIAGKVIHALGQS

LPXN

156

O60711
GKHIFNKVLGPNGLL

ABCC2

796

Q92887
PNGLLKGKTRLLVTH

ABCC2

806

Q92887
QLTKGSVLVNGHPVL

MUC5AC

146

P98088
NVSKLNILKLAPGGH

RPL4

231

P36578
LLQHKSPSALGKGVL

IQSEC3

166

Q9UPP2
RGPTSLLGKVVKTHQ

ALAS2

16

P22557
SIINPHNLKGKSLGQ

MACF1

2871

Q9UPN3
KGGPQSLVILLNKST

HMCN1

3716

Q96RW7
ESKNKHGLTPLLLGV

POTEE

266

Q6S8J3
SSGIKGSLPLQKLHL

OPA1

21

O60313
PIGAKIQTLHLVGVN

FBXO38

186

Q6PIJ6
KSHDLKPNGGNILVT

ITCH

716

Q96J02
AKNRKGIAIIIHGTP

HYDIN

2031

Q4G0P3
GHSEKLPLILKNNGV

HYDIN

3501

Q4G0P3
PITNSLIGKDGQVHL

C17orf99

156

Q6UX52
LGIILAKAVISKHPG

HEATR5A

236

Q86XA9
GQDKLLGLVKLPLHQ

C2CD3

891

Q4AC94
NLKQPLLHEGKNGVL

CGNL1

116

Q0VF96
NKSHIITGNKIPLSG

CDC7

226

O00311
NSGAVLGKTRKNHIP

UPB1

186

Q9UBR1
LSGISLQKKLQHVPG

CBWD3

251

Q5JTY5
LSGISLQKKLQHVPG

CBWD6

251

Q4V339
LSSLKVKGLVLGPIH

SLC3A2

251

P08195
PLHLGKLPTQQVKQL

ANGPT4

76

Q9Y264
LVIGAIVKNKNLHSP

MC5R

56

P33032
TLVKLARGHTNGTKP

ARSB

356

P15848
GNISIPKSNGLIIKH

ENO4

481

A6NNW6
NLTHLPKGLLGAQAK

GP5

181

P40197
IPHIHKSLIGKKGQQ

H2AZ1

111

P0C0S5
PGSKEHVLQINKLTG

IGFN1

81

Q86VF2
LKLHAVVQGLGPTFK

BBS1

486

Q8NFJ9
GQKLSIPQITTKHSG

PSG4

376

Q00888
GITQILGKSHGSLKL

C18orf63

576

Q68DL7
GIHPKNIQSLEVIGK

PPBP

71

P02775
LGKPLVLQAALHGQS

JADE3

636

Q92613
NTGIGQHILKNPLII

DIMT1

31

Q9UNQ2
GQKLFIPQITTKHSG

PSG3

376

Q16557
KGGLTPLLLAVHGQK

POTEA

196

Q6S8J7
ISLLHSPGNIGKLLG

NUP88

281

Q99567
HLGKQLAGTLLQLGP

NOXRED1

86

Q6NXP6
QAKLPSGKLQVHLRG

MTX1

361

Q13505
LALPKGGNKHLSNLT

RTTN

2061

Q86VV8
HLVGLTKLNLGKNSL

LRRC15

171

Q8TF66
GKVASLGPIKQHTFL

NDUFAF7

346

Q7L592
GQHILKNGLSLLKIG

YARS2

451

Q9Y2Z4
GQKLFIPQITTKHSG

PSG8

376

Q9UQ74
IQKNRLLGKQTGLTP

ENTPD4

346

Q9Y227
LLNKHPGVNVQITGL

PKD1L3

456

Q7Z443
KNKHGLTPLLLGVHE

POTEJ

231

P0CG39
ILSNNLLKKLPHGLG

SHOC2

431

Q9UQ13
PTKVVHRQGLLGVQK

PPP1R26

271

Q5T8A7
ESKNKHGLTPLLLGV

POTEI

266

P0CG38
GIVHKDIKPGNLLLT

STK11

171

Q15831
GQKLSIPQITTKHSG

PSG7

376

Q13046
GLLVPALKKVQGQVH

SOS1

21

Q07889
SGGKLHLTKNGVISL

RASGRF1

506

Q13972
HLPLSKLQQGIKSGT

DIS3

231

Q9Y2L1
TLIGVQNPSLLKGKS

TET1

171

Q8NFU7
LKHVNALIAPGQKIG

ABCC8

1361

Q09428
GPKSKVLILRNHGLV

ADD1

291

P35611
NGGLNLHSPVKRKLE

CDYL2

211

Q8N8U2
QQPKLSGSLKFLGHL

CNOT10

561

Q9H9A5
SGHSLILILGNPKLK

TAS2R1

271

Q9NYW7
LALHIKIISGQNFPK

PLCL1

721

Q15111
TLAVQGISGLPLKKQ

TSR1

186

Q2NL82
RGDKQGLLLLHNKTP

TULP2

436

O00295
LSGLSKHVQTDPGQK

ZNF778

321

Q96MU6
KVKVGHIGNLKLIIP

VPS13A

56

Q96RL7
TKALVLNGKPGHLQF

WDR75

346

Q8IWA0
GPSKLVQKHLAGLFN

PSME4

321

Q14997
YAGNIKTLQKLPHIL

SLF1

1011

Q9BQI6
GNKLQTLSPSHKGIA

ZC2HC1A

216

Q96GY0
LVPGKIQHILCTGNL

VPS29

26

Q9UBQ0
LQSLPGKQLPSHKAI

XPNPEP3

136

Q9NQH7
KNGIPLESNHTIKAG

KDR

366

P35968
PAKLHNSLIGTKGRL

HDLBP

661

Q00341
ANLTGSHKLKPLVIG

TIGD5

281

Q53EQ6
ESKNKHGLTPLLLGV

POTEG

266

Q6S5H5
ESKNKHGLTPLLLGV

POTEM

266

A6NI47
KNLATVGGQIIKPSL

ZNF426

76

Q9BUY5
VLTGLQSGQPKHLLL

SHC1

521

P29353
LLHIFTVNKQLGPKI

TRPM4

906

Q8TD43
KKQLSHLNVINDGGP

VPS54

926

Q9P1Q0