Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 HOXD11 IRX4 FOXD1

8.09e-0612443010GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 HOXD11 IRX4 FOXD1

9.77e-0612713010GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 HOXD11 IRX4 FOXD1

2.45e-0514123010GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 HOXD11 IRX4 FOXD1

3.26e-0514593010GO:0000977
GeneOntologyMolecularFunctionstructural constituent of muscle

CSRP3 CSRP1 CSRP2

3.63e-0543303GO:0008307
GeneOntologyMolecularFunctionactinin binding

CSRP3 CSRP1 CSRP2

3.63e-0543303GO:0042805
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXD1

1.58e-04560306GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXD1

1.68e-04566306GO:0001216
GeneOntologyBiologicalProcessatrial cardiac muscle cell development

NKX2-5 NKX2-6

6.13e-063302GO:0055014
GeneOntologyBiologicalProcessatrial cardiac muscle cell differentiation

NKX2-5 NKX2-6

6.13e-063302GO:0055011
GeneOntologyBiologicalProcessmyofibril assembly

NKX2-5 CSRP3 CSRP1 CSRP2

7.11e-0686304GO:0030239
GeneOntologyBiologicalProcessstriated muscle cell development

NKX2-5 CSRP3 CSRP1 CSRP2

8.15e-0689304GO:0055002
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

NKX2-3 PLA2G1B HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 CSRP3 FOXD1

1.61e-0513903010GO:0045944
GeneOntologyBiologicalProcessstriated muscle cell differentiation

NKX2-5 NKX2-6 ADAMTS5 CSRP3 CSRP1 CSRP2

1.80e-05391306GO:0051146
GeneOntologyBiologicalProcessmuscle cell development

NKX2-5 NKX2-6 CSRP3 CSRP1 CSRP2

3.31e-05259305GO:0055001
GeneOntologyBiologicalProcessanimal organ morphogenesis

NKX2-3 HOXA13 NKX2-5 OTX1 ADAMTS5 FBN2 HOXD11 IRX4 FOXD1

5.40e-051269309GO:0009887
GeneOntologyBiologicalProcesscellular component assembly involved in morphogenesis

NKX2-5 CSRP3 CSRP1 CSRP2

7.40e-05156304GO:0010927
GeneOntologyBiologicalProcesscellular anatomical entity morphogenesis

NKX2-5 CSRP3 CSRP1 CSRP2

7.40e-05156304GO:0032989
GeneOntologyBiologicalProcesssarcomere organization

CSRP3 CSRP1 CSRP2

8.54e-0559303GO:0045214
GeneOntologyBiologicalProcessmuscle cell differentiation

NKX2-5 NKX2-6 ADAMTS5 CSRP3 CSRP1 CSRP2

9.93e-05531306GO:0042692
GeneOntologyBiologicalProcessventricular cardiac muscle cell development

NKX2-5 NKX2-6

1.34e-0412302GO:0055015
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

NKX2-5 PHOX2A ADAMTS5 FBN2 HOXD11 CSRP3 FOXD1 CSRP1 CSRP2

1.80e-041483309GO:0048646
GeneOntologyBiologicalProcessventricular cardiac muscle cell differentiation

NKX2-5 NKX2-6

3.44e-0419302GO:0055012
GeneOntologyBiologicalProcessactomyosin structure organization

NKX2-5 CSRP3 CSRP1 CSRP2

3.80e-04239304GO:0031032
GeneOntologyBiologicalProcesscardiac myofibril assembly

NKX2-5 CSRP3

4.22e-0421302GO:0055003
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

HOXA13 HOXD11 FOXD1 FIGNL2

5.07e-04258304GO:0001763
GeneOntologyBiologicalProcesstissue morphogenesis

HOXA13 NKX2-5 ADAMTS5 HOXD11 FOXD1 FIGNL2

6.37e-04750306GO:0048729
GeneOntologyBiologicalProcessheart development

HOXA13 NKX2-5 NKX2-6 ADAMTS5 CSRP3 IRX4

6.69e-04757306GO:0007507
GeneOntologyBiologicalProcesstongue development

NKX2-5 NKX2-6

7.02e-0427302GO:0043586
GeneOntologyBiologicalProcesscardiac muscle cell development

NKX2-5 NKX2-6 CSRP3

7.29e-04122303GO:0055013
GeneOntologyBiologicalProcesspattern specification process

NKX2-5 OTX1 HOXD11 IRX4 FOXD1

8.90e-04526305GO:0007389
GeneOntologyBiologicalProcesscardiac cell development

NKX2-5 NKX2-6 CSRP3

9.17e-04132303GO:0055006
GeneOntologyBiologicalProcesstrabecula formation

NKX2-5 FBN2

9.87e-0432302GO:0060343
GeneOntologyBiologicalProcesspharyngeal system development

NKX2-5 NKX2-6

1.11e-0334302GO:0060037
GeneOntologyBiologicalProcessmuscle tissue development

NKX2-5 NKX2-6 CSRP3 CSRP1 CSRP2

1.16e-03558305GO:0060537
GeneOntologyBiologicalProcessembryonic limb morphogenesis

HOXA13 FBN2 HOXD11

1.28e-03148303GO:0030326
GeneOntologyBiologicalProcessembryonic appendage morphogenesis

HOXA13 FBN2 HOXD11

1.28e-03148303GO:0035113
GeneOntologyBiologicalProcessmuscle structure development

NKX2-5 NKX2-6 ADAMTS5 CSRP3 CSRP1 CSRP2

1.28e-03858306GO:0061061
GeneOntologyBiologicalProcessembryonic forelimb morphogenesis

HOXA13 HOXD11

1.32e-0337302GO:0035115
GeneOntologyBiologicalProcessregulation of epithelial cell apoptotic process

PLA2G1B NKX2-5 NKX2-6

1.38e-03152303GO:1904035
GeneOntologyBiologicalProcessdigestive tract development

NKX2-3 HOXA13 NKX2-6

1.38e-03152303GO:0048565
GeneOntologyBiologicalProcessaortic valve morphogenesis

NKX2-5 ADAMTS5

1.47e-0339302GO:0003180
GeneOntologyBiologicalProcessmyotube differentiation

NKX2-5 ADAMTS5 CSRP3

1.71e-03164303GO:0014902
GeneOntologyBiologicalProcessdigestive system development

NKX2-3 HOXA13 NKX2-6

1.80e-03167303GO:0055123
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

HOXA13 NKX2-5 HOXD11 FOXD1 FIGNL2

1.83e-03619305GO:0002009
GeneOntologyBiologicalProcessaortic valve development

NKX2-5 ADAMTS5

2.03e-0346302GO:0003176
GeneOntologyBiologicalProcesscardiac muscle cell differentiation

NKX2-5 NKX2-6 CSRP3

2.13e-03177303GO:0055007
GeneOntologyBiologicalProcessforelimb morphogenesis

HOXA13 HOXD11

2.21e-0348302GO:0035136
GeneOntologyBiologicalProcesssemi-lunar valve development

NKX2-5 ADAMTS5

2.40e-0350302GO:1905314
GeneOntologyBiologicalProcessappendage morphogenesis

HOXA13 FBN2 HOXD11

2.41e-03185303GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

HOXA13 FBN2 HOXD11

2.41e-03185303GO:0035108
GeneOntologyBiologicalProcessspleen development

NKX2-3 NKX2-5

2.59e-0352302GO:0048536
GeneOntologyBiologicalProcessepithelial cell apoptotic process

PLA2G1B NKX2-5 NKX2-6

2.68e-03192303GO:1904019
GeneOntologyBiologicalProcessregulation of myotube differentiation

NKX2-5 CSRP3

2.89e-0355302GO:0010830
GeneOntologyBiologicalProcesstrabecula morphogenesis

NKX2-5 FBN2

3.11e-0357302GO:0061383
GeneOntologyBiologicalProcessdigestive tract morphogenesis

NKX2-3 HOXA13

3.32e-0359302GO:0048546
GeneOntologyBiologicalProcessembryonic morphogenesis

HOXA13 NKX2-5 OTX1 FBN2 HOXD11

3.38e-03713305GO:0048598
GeneOntologyBiologicalProcessheart valve morphogenesis

NKX2-5 ADAMTS5

3.78e-0363302GO:0003179
GeneOntologyBiologicalProcesscardiocyte differentiation

NKX2-5 NKX2-6 CSRP3

3.98e-03221303GO:0035051
GeneOntologyBiologicalProcesslimb development

HOXA13 FBN2 HOXD11

4.13e-03224303GO:0060173
GeneOntologyBiologicalProcessappendage development

HOXA13 FBN2 HOXD11

4.13e-03224303GO:0048736
GeneOntologyBiologicalProcessepithelium development

HOXA13 NKX2-5 NKX2-6 FOXA3 HOXD11 FOXD1 FIGNL2

4.36e-031469307GO:0060429
GeneOntologyBiologicalProcessbranching involved in ureteric bud morphogenesis

HOXD11 FOXD1

4.39e-0368302GO:0001658
GeneOntologyBiologicalProcessmembraneless organelle assembly

NKX2-5 CSRP3 CSRP1 CSRP2

4.74e-03475304GO:0140694
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

HOXA13 HOXD11 FOXD1

4.78e-03236303GO:0061138
GeneOntologyBiologicalProcessregionalization

NKX2-5 OTX1 HOXD11 FOXD1

4.84e-03478304GO:0003002
GeneOntologyCellularComponentintermediate filament cytoskeleton

HOXA13 KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

9.36e-08263317GO:0045111
GeneOntologyCellularComponentintermediate filament

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

9.01e-07227316GO:0005882
GeneOntologyCellularComponentsupramolecular fiber

KRTAP8-1 FBN2 KRTAP19-8 KRTAP13-3 CSRP3 KRTAP19-5 KRTAP19-3 CSRP1 CSRP2 KRTAP22-1

4.68e-0611793110GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRTAP8-1 FBN2 KRTAP19-8 KRTAP13-3 CSRP3 KRTAP19-5 KRTAP19-3 CSRP1 CSRP2 KRTAP22-1

4.97e-0611873110GO:0099081
GeneOntologyCellularComponentchromatin

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 HOXD11 IRX4 FOXD1

3.43e-0514803110GO:0000785
GeneOntologyCellularComponentZ disc

CSRP3 CSRP1 CSRP2

1.43e-03151313GO:0030018
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

1.82e-03899316GO:0099513
GeneOntologyCellularComponentI band

CSRP3 CSRP1 CSRP2

1.88e-03166313GO:0031674
GeneOntologyCellularComponentsarcomere

CSRP3 CSRP1 CSRP2

5.87e-03249313GO:0030017
GeneOntologyCellularComponentmyofibril

CSRP3 CSRP1 CSRP2

7.56e-03273313GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

CSRP3 CSRP1 CSRP2

8.91e-03290313GO:0043292
MousePhenoabnormal carpal bone morphology

HOXA13 FBN2 HOXD11

3.47e-0536253MP:0000554
DomainKRTAP

KRTAP8-1 KRTAP19-8 KRTAP19-5 KRTAP19-3 KRTAP22-1

2.66e-1115315PF11759
DomainKRTAP_type6/8/16/19/20/21

KRTAP8-1 KRTAP19-8 KRTAP19-5 KRTAP19-3 KRTAP22-1

2.66e-1115315IPR021743
DomainHomeobox_CS

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

5.40e-10186318IPR017970
DomainHomeobox

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

3.31e-09234318PF00046
DomainHOMEOBOX_1

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

3.54e-09236318PS00027
DomainHOX

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

3.66e-09237318SM00389
DomainHomeobox_dom

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

3.91e-09239318IPR001356
DomainHOMEOBOX_2

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

3.91e-09239318PS50071
Domain-

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

1.47e-082833181.10.10.60
DomainHomeodomain-like

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 HOXD11 IRX4

5.06e-08332318IPR009057
DomainHomeobox_metazoa

NKX2-3 NKX2-5 NKX2-6 HOXD11

1.44e-0590314IPR020479
DomainLIM

CSRP3 CSRP1 CSRP2

2.01e-0469313PF00412
Domain-

CSRP3 CSRP1 CSRP2

2.10e-04703132.10.110.10
DomainLIM_DOMAIN_2

CSRP3 CSRP1 CSRP2

2.19e-0471313PS50023
DomainZnf_LIM

CSRP3 CSRP1 CSRP2

2.19e-0471313IPR001781
DomainLIM_DOMAIN_1

CSRP3 CSRP1 CSRP2

2.19e-0471313PS00478
DomainLIM

CSRP3 CSRP1 CSRP2

2.19e-0471313SM00132
DomainTF_fork_head_CS_2

FOXA3 FOXD1

2.64e-0346312IPR030456
DomainTF_fork_head_CS_1

FOXA3 FOXD1

2.75e-0347312IPR018122
DomainFORK_HEAD_3

FOXA3 FOXD1

2.99e-0349312PS50039
DomainFH

FOXA3 FOXD1

2.99e-0349312SM00339
DomainFORK_HEAD_1

FOXA3 FOXD1

2.99e-0349312PS00657
DomainFORK_HEAD_2

FOXA3 FOXD1

2.99e-0349312PS00658
DomainForkhead

FOXA3 FOXD1

2.99e-0349312PF00250
DomainFork_head_dom

FOXA3 FOXD1

2.99e-0349312IPR001766
DomainHTH_motif

NKX2-3 PHOX2A

5.84e-0369312IPR000047
Domain-

CNTNAP4 MYCBP2

6.51e-03733122.60.120.260
DomainGalactose-bd-like

CNTNAP4 MYCBP2

1.06e-0294312IPR008979
PathwayREACTOME_KERATINIZATION

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

2.80e-06217276M27640
PathwayREACTOME_KERATINIZATION

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3

9.39e-06153275MM15343
Pubmed

Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3

2.46e-121731515385554
Pubmed

The heart LIM protein gene (Hlp), expressed in the developing and adult heart, defines a new tissue-specific LIM-only protein family.

NKX2-5 CSRP3 CSRP1 CSRP2

3.60e-11831412128222
Pubmed

Isolation and characterization of mouse high-glycine/tyrosine proteins.

KRTAP8-1 KRTAP19-8 KRTAP19-5 KRTAP19-3

1.08e-10103149374545
Pubmed

Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.

KRTAP8-1 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

2.58e-104031512359730
Pubmed

Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system.

CSRP3 CSRP1 CSRP2

2.56e-0943139815145
Pubmed

Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3

4.33e-096931518721477
Pubmed

NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis.

NKX2-3 NKX2-5 NKX2-6

6.40e-09531312141427
Pubmed

Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting.

NKX2-3 NKX2-5 NKX2-6

2.24e-08731310733590
Pubmed

NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos.

NKX2-3 NKX2-5 NKX2-6

2.24e-08731310603087
Pubmed

Sequence and chromosomal assignment of human BAPX1, a bagpipe-related gene, to 4p16.1: a candidate gene for skeletal dysplasia.

NKX2-3 NKX2-5 NKX2-6

5.37e-0893139344671
Pubmed

A census of human transcription factors: function, expression and evolution.

NKX2-3 HOXA13 NKX2-5 PHOX2A NKX2-6 OTX1 FOXA3 HOXD11 IRX4

6.52e-0890831919274049
Pubmed

The emergent landscape of the mouse gut endoderm at single-cell resolution.

HOXA13 NKX2-5 FOXA3 HOXD11

9.77e-084831430959515
Pubmed

Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia.

KRTAP19-8 KRTAP19-5 KRTAP19-3

1.40e-071231311290294
Pubmed

Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.

NKX2-3 NKX2-5 PHOX2A FOXA3

1.97e-075731421122108
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

NKX2-3 HOXA13 NKX2-5 PHOX2A OTX1 FOXA3 HOXD11

4.19e-0754431728473536
Pubmed

Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1.

KRTAP19-8 KRTAP19-5 KRTAP19-3

6.15e-071931315234001
Pubmed

Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants.

NKX2-5 NKX2-6

7.69e-0723127904557
Pubmed

Common arterial trunk associated with a homeodomain mutation of NKX2.6.

NKX2-5 NKX2-6

7.69e-07231215649947
Pubmed

Loss of the serum response factor cofactor, cysteine-rich protein 1, attenuates neointima formation in the mouse.

CSRP1 CSRP2

7.69e-07231220056913
Pubmed

Assignment of cardiac homeobox gene CSX to human chromosome 5q34.

NKX2-5 NKX2-6

7.69e-0723127665173
Pubmed

NKX2.5/NKX2.6 mutations are not a common cause of isolated type 1 truncus arteriosus in a small cohort of multiethnic cases.

NKX2-5 NKX2-6

7.69e-07231218939937
Pubmed

Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure.

CSRP3 CSRP2

7.69e-07231218713466
Pubmed

PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling.

CSRP3 CSRP2

2.31e-06331218258855
Pubmed

Functional specificity of the Hoxa13 homeobox.

HOXA13 HOXD11

2.31e-06331211688568
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

HOXA13 PHOX2A NKX2-6 OTX1 IRX4

3.44e-0626331520932939
Pubmed

Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.

HOXD11 FOXD1

4.61e-06431212060755
Pubmed

Xnkx-2.1: a homeobox gene expressed during early forebrain, lung and thyroid development in Xenopus laevis.

NKX2-3 NKX2-5

4.61e-06431211180810
Pubmed

The cysteine-rich protein family of highly related LIM domain proteins.

CSRP3 CSRP2

4.61e-0643127499425
Pubmed

Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles.

KRTAP19-8 KRTAP19-5 KRTAP19-3

4.88e-063731317151017
Pubmed

Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.

NKX2-5 ADAMTS5 IRX4

5.30e-063831318267097
Pubmed

Altered Hox expression and increased cell death distinguish Hypodactyly from Hoxa13 null mice.

HOXA13 HOXD11

7.68e-06531210470645
Pubmed

A group 13 homeodomain is neither necessary nor sufficient for posterior prevalence in the mouse limb.

HOXA13 HOXD11

7.68e-06531216806154
Pubmed

The developing heart and congenital heart defects: a make or break situation.

NKX2-5 IRX4

7.68e-06531212702154
Pubmed

Fork stalling and template switching as a mechanism for polyalanine tract expansion affecting the DYC mutant of HOXD13, a new murine model of synpolydactyly.

HOXA13 HOXD11

7.68e-06531219546318
Pubmed

Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications.

HOXA13 HOXD11

7.68e-0653129391088
Pubmed

The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes.

HOXA13 HOXD11

7.68e-06531211543619
Pubmed

Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development.

NKX2-5 NKX2-6

1.15e-0563129621431
Pubmed

Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development.

NKX2-5 IRX4

1.15e-05631224123507
Pubmed

Context-dependent enhancer function revealed by targeted inter-TAD relocation.

HOXA13 HOXD11

1.15e-05631235715427
Pubmed

Differential expression of two different homeobox gene families during mouse tegument morphogenesis.

OTX1 HOXD11

1.15e-0563127779685
Pubmed

Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism.

HOXA13 HOXD11

1.61e-05731223239739
Pubmed

The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively.

NKX2-3 NKX2-6

1.61e-0573128001981
Pubmed

Identification of transcripts with enriched expression in the developing and adult pancreas.

NKX2-3 FBN2 UQCRFS1 FOXA3 CSRP3 CSRP1

1.64e-0562431618554416
Pubmed

Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand.

NKX2-5 IRX4

2.15e-05831210625552
Pubmed

Similarities and differences in the regulation of HoxD genes during chick and mouse limb development.

HOXA13 HOXD11

2.15e-05831230475793
Pubmed

Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system.

NKX2-5 IRX4

2.15e-05831215680351
Pubmed

Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model.

HOXA13 HOXD11

2.15e-05831226238020
Pubmed

Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle.

NKX2-5 FOXA3

2.76e-05931232179481
Pubmed

"Self-regulation," a new facet of Hox genes' function.

HOXA13 HOXD11

2.76e-05931223913823
Pubmed

Chamber formation and morphogenesis in the developing mammalian heart.

NKX2-5 IRX4

2.76e-05931210882515
Pubmed

Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.

NKX2-5 IRX4

3.44e-051031211923873
Pubmed

A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function.

NKX2-5 NKX2-6

3.44e-051031222087235
Pubmed

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

HOXA13 HOXD11

3.44e-051031212215652
Pubmed

Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification.

NKX2-5 IRX4

3.44e-051031227052172
Pubmed

Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx.

NKX2-5 NKX2-6

3.44e-051031211390666
Pubmed

The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation.

NKX2-5 IRX4

4.21e-051131211784028
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

NKX2-5 IRX4

4.21e-051131210926765
Pubmed

Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family.

FOXA3 FOXD1

4.21e-05113127683413
Pubmed

The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly.

NKX2-5 CSRP3

4.21e-051131227217161
Pubmed

LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes.

HOXA13 HOXD11

5.05e-051231226633036
Pubmed

Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart.

NKX2-5 IRX4

5.05e-051231217050624
Pubmed

Functional analysis of CTCF during mammalian limb development.

HOXA13 HOXD11

5.05e-051231221145498
Pubmed

Pax3 and Tbx5 specify whether PDGFRα+ cells assume skeletal or cardiac muscle fate in differentiating embryonic stem cells.

NKX2-5 PHOX2A

5.96e-051331224677751
Pubmed

Identification of downstream genetic pathways of Tbx1 in the second heart field.

NKX2-5 NKX2-6

5.96e-051331218328475
Pubmed

FOXD1 is required for 3D patterning of the kidney interstitial matrix.

FBN2 FOXD1

5.96e-051331236335435
Pubmed

Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity.

HOXA13 HOXD11

6.95e-05143129834182
Pubmed

Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney.

HOXD11 FOXD1

6.95e-051431211493536
Pubmed

The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning.

HOXA13 HOXD11

6.95e-05143129342041
Pubmed

Conditional ablation of the heparan sulfate-synthesizing enzyme Ext1 leads to dysregulation of bone morphogenic protein signaling and severe skeletal defects.

HOXA13 HOXD11

8.02e-051531220404326
Pubmed

Erythrocyte-derived sphingosine 1-phosphate is essential for vascular development.

NKX2-5 IRX4

8.02e-051531225250575
Pubmed

The apical ectodermal ridge is a timer for generating distal limb progenitors.

HOXA13 HOXD11

8.02e-051531218359901
Pubmed

Hoxd and Gli3 interactions modulate digit number in the amniote limb.

HOXA13 HOXD11

8.02e-051531217714700
Pubmed

BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning.

HOXA13 HOXD11

8.02e-051531216630606
Pubmed

Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods.

HOXA13 HOXD11

9.16e-051631210075839
Pubmed

Loss of the Tg737 protein results in skeletal patterning defects.

HOXA13 HOXD11

9.16e-051631212701101
Pubmed

Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice.

HOXA13 HOXD11

9.16e-051631217222543
Pubmed

In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth.

HOXA13 HOXD11

9.16e-051631219210962
Pubmed

Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.

HOXA13 HOXD11

9.16e-051631227974206
Pubmed

Nipbl and mediator cooperatively regulate gene expression to control limb development.

HOXA13 HOXD11

9.16e-051631225255084
Pubmed

Ezh2 regulates anteroposterior axis specification and proximodistal axis elongation in the developing limb.

HOXA13 HOXD11

9.16e-051631221795281
Pubmed

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.

NKX2-5 IRX4

1.04e-041731211572777
Pubmed

Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.

HOXA13 HOXD11

1.04e-041731219168674
Pubmed

The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements.

HOXA13 HOXD11

1.04e-041731211850178
Pubmed

Geminin is required for Hox gene regulation to pattern the developing limb.

HOXA13 HOXD11

1.04e-041731232450229
Pubmed

Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding.

HOXA13 HOXD11

1.04e-041731224075990
Pubmed

Meis1 coordinates a network of genes implicated in eye development and microphthalmia.

OTX1 FOXD1

1.17e-041831226253404
Pubmed

Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development.

HOXA13 HOXD11

1.17e-041831220386744
Pubmed

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

NKX2-5 IRX4

1.17e-041831228846746
Pubmed

Fgf8 signalling from the AER is essential for normal limb development.

HOXA13 HOXD11

1.17e-041831211101846
Pubmed

Plzf regulates limb and axial skeletal patterning.

HOXA13 HOXD11

1.30e-041931210835630
Pubmed

Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma.

HOXD11 FOXD1

1.30e-041931221858105
Pubmed

Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.

NKX2-5 IRX4

1.30e-041931220651287
Pubmed

Shox2 regulates progression through chondrogenesis in the mouse proximal limb.

HOXA13 HOXD11

1.30e-041931223038774
Pubmed

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.

NKX2-5 IRX4

1.45e-042031223314057
Pubmed

Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.

NKX2-5 IRX4

1.45e-042031211245568
Pubmed

T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis.

NKX2-5 IRX4

1.76e-042231215843407
Pubmed

Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs.

HOXA13 HOXD11

1.76e-042231226283362
Pubmed

A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo.

HOXA13 HOXD11

1.76e-042231210021340
Pubmed

Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.

HOXA13 HOXD11

1.92e-042331216672333
Pubmed

Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.

NKX2-5 ADAMTS5

2.10e-042431229791855
InteractionRBPMS interactions

NKX2-5 KRTAP8-1 OTX1 RTP5 KRTAP13-3 KRTAP19-5 KRTAP19-3

5.33e-07340307int:RBPMS
InteractionARID5A interactions

KRTAP8-1 OTX1 KRTAP19-5 KRTAP19-3 KRTAP22-1

2.37e-06147305int:ARID5A
InteractionMGAT5B interactions

OTX1 KRTAP13-3 KRTAP19-5 KRTAP22-1

2.91e-05120304int:MGAT5B
InteractionCAMK2A interactions

KRTAP8-1 MYCBP2 KRTAP19-5 KRTAP19-3 KRTAP22-1

5.27e-05279305int:CAMK2A
InteractionSMR3A interactions

KRTAP8-1 KRTAP19-3

5.96e-058302int:SMR3A
InteractionKRTAP12-4 interactions

KRTAP8-1 OTX1 KRTAP19-5

6.63e-0553303int:KRTAP12-4
InteractionPOU2AF1 interactions

OTX1 KRTAP19-5 KRTAP19-3

7.82e-0556303int:POU2AF1
InteractionPRR13 interactions

KRTAP8-1 OTX1 KRTAP19-5

7.82e-0556303int:PRR13
InteractionCREB5 interactions

KRTAP8-1 KRTAP19-5 KRTAP19-3 KRTAP22-1

9.82e-05164304int:CREB5
InteractionCCDC17 interactions

KRTAP8-1 KRTAP19-5

1.40e-0412302int:CCDC17
InteractionKRTAP8-1 interactions

NKX2-5 KRTAP8-1 KRTAP19-5

2.18e-0479303int:KRTAP8-1
InteractionKRTAP22-1 interactions

OTX1 KRTAP22-1

2.22e-0415302int:KRTAP22-1
InteractionRBPMS2 interactions

KRTAP8-1 MYCBP2 KRTAP19-5

2.52e-0483303int:RBPMS2
InteractionC11orf16 interactions

KRTAP8-1 KRTAP19-5

2.54e-0416302int:C11orf16
InteractionRNF44 interactions

KRTAP19-5 KRTAP22-1

2.54e-0416302int:RNF44
InteractionCHRD interactions

OTX1 KRTAP19-5 KRTAP22-1

3.64e-0494303int:CHRD
InteractionKRTAP19-5 interactions

KRTAP8-1 RTP5 KRTAP19-5

4.24e-0499303int:KRTAP19-5
InteractionGLIS2 interactions

KRTAP8-1 KRTAP19-5 KRTAP19-3

5.18e-04106303int:GLIS2
InteractionXPNPEP1 interactions

UQCRFS1 CSRP3 GARS1

5.77e-04110303int:XPNPEP1
InteractionFOXD2 interactions

KRTAP8-1 KRTAP22-1

6.29e-0425302int:FOXD2
InteractionZIC1 interactions

KRTAP8-1 KRTAP19-5 KRTAP22-1

6.74e-04116303int:ZIC1
Cytoband21q22.1

KRTAP8-1 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

5.67e-113931521q22.1
CytobandEnsembl 112 genes in cytogenetic band chr21q22

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

1.82e-07377316chr21q22
GeneFamilyKeratin associated proteins

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 KRTAP19-3 KRTAP22-1

1.41e-08109286619
GeneFamilyLIM domain containing

CSRP3 CSRP1 CSRP2

1.02e-04592831218
GeneFamilyNKL subclass homeoboxes and pseudogenes

NKX2-3 NKX2-5 NKX2-6

1.49e-0467283519
GeneFamilyForkhead boxes

FOXA3 FOXD1

2.01e-0343282508
GeneFamilyHOXL subclass homeoboxes

HOXA13 HOXD11

2.92e-0352282518
GeneFamilyPRD class homeoboxes and pseudogenes

PHOX2A OTX1

8.88e-0392282521
CoexpressionDESCARTES_ORGANOGENESIS_CARDIAC_MUSCLE_LINEAGES

NKX2-5 UQCRFS1 CSRP3 IRX4 CSRP1 CSRP2

6.58e-08182316MM3637
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRTAP8-1 KRTAP19-8 KRTAP13-3 KRTAP19-5 IRX4 KRTAP19-3

1.29e-07204316MM966
CoexpressionMARTINEZ_RB1_TARGETS_DN

KRTAP8-1 FBN2 KRTAP19-8 KRTAP13-3 CSRP3 KRTAP19-5 IRX4 KRTAP19-3

5.16e-07630318MM1038
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

HOXA13 NKX2-5 PHOX2A RBMXL3 HOXD11 IRX4

8.64e-07282316MM822
CoexpressionBENPORATH_EED_TARGETS

NKX2-3 HOXA13 NKX2-5 PHOX2A OTX1 ADAMTS5 FBN2 HOXD11 IRX4

2.50e-061059319M7617
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

KRTAP8-1 FBN2 KRTAP19-8 KRTAP13-3 KRTAP19-5 IRX4 KRTAP19-3

8.75e-06650317MM1042
CoexpressionMARTINEZ_TP53_TARGETS_DN

KRTAP8-1 FBN2 KRTAP19-8 KRTAP13-3 KRTAP19-5 IRX4 KRTAP19-3

9.56e-06659317MM1040
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

HOXA13 NKX2-5 PHOX2A HOXD11 IRX4

1.58e-05272315M1938
CoexpressionMARTINEZ_RB1_TARGETS_DN

KRTAP8-1 FBN2 KRTAP19-8 CSRP3 IRX4 KRTAP19-3

4.73e-05569316M12701
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRTAP8-1 KRTAP19-8 IRX4 KRTAP19-3

5.02e-05173314M650
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NKX2-3 NKX2-5 HOXD11 MYCBP2 IRX4

1.51e-04438315M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

NKX2-3 NKX2-5 HOXD11 MYCBP2 IRX4

1.54e-04440315MM832
CoexpressionBENPORATH_SUZ12_TARGETS

NKX2-3 PHOX2A OTX1 ADAMTS5 FBN2 HOXD11 IRX4

1.68e-041035317M9898
CoexpressionKONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3

NKX2-3 HOXD11 IRX4

2.05e-0497313M16734
CoexpressionBENPORATH_ES_WITH_H3K27ME3

NKX2-3 HOXA13 NKX2-5 PHOX2A OTX1 FBN2 IRX4

2.65e-041115317M10371
CoexpressionCUI_DEVELOPING_HEART_CARDIAC_FIBROBLASTS

NKX2-5 CSRP3 CSRP1

2.66e-04106313M39317
CoexpressionIKEDA_MIR30_TARGETS_DN

ANO4 IRX4

3.68e-0424312MM932
CoexpressionIKEDA_MIR30_TARGETS_DN

ANO4 IRX4

3.68e-0424312M2380
CoexpressionWANG_MLL_TARGETS

ANO4 HOXA13 FBN2 FOXD1

3.84e-04294314M2456
CoexpressionINGRAM_SHH_TARGETS_UP

NKX2-5 FBN2 FOXD1

4.32e-04125313M1320
CoexpressionWANG_MLL_TARGETS

ANO4 HOXA13 FBN2 FOXD1

4.47e-04306314MM1076
CoexpressionYOSHIMURA_MAPK8_TARGETS_UP

PLA2G1B PHOX2A OTX1 UQCRFS1 FOXA3 CSRP3 FOXD1

6.13e-041281317M1884
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

NKX2-3 NKX2-5 PHOX2A RBMXL3 IRX4

6.46e-04601315MM866
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

KRTAP8-1 FBN2 KRTAP19-8 IRX4 KRTAP19-3

6.91e-04610315M3854
CoexpressionDESCARTES_ORGANOGENESIS_LIMB_MESENCHYME

HOXA13 HOXD11

6.99e-0433312MM3669
CoexpressionMARTINEZ_TP53_TARGETS_DN

KRTAP8-1 FBN2 KRTAP19-8 IRX4 KRTAP19-3

7.17e-04615315M8673
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

CNTNAP4 HOXA13 PHOX2A OTX1 ADAMTS5 FBN2 HOXD11 CSRP1

3.29e-051094268ratio_EB_vs_SC_2500_K3
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_200

ANO4 CNTNAP4 FOXD1

7.75e-0568263gudmap_developingKidney_e13.5_podocyte cells_200_k4
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500

ANO4 CNTNAP4 FBN2 FOXD1 CSRP1

9.52e-05388265gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#1_top-relative-expression-ranked_1000

CNTNAP4 HOXA13 PHOX2A ADAMTS5

1.33e-04217264DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k1_1000
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_100

ANO4 CNTNAP4 FOXD1

1.73e-0489263gudmap_developingKidney_e13.5_podocyte cells_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#4_top-relative-expression-ranked_100

CNTNAP4 HOXA13

1.94e-0417262DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k4_100
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000

CNTNAP4 HOXA13 FBN2 CSRP2

2.69e-04261264gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

ANO4 CNTNAP4 ADAMTS5 FBN2 FOXD1 CSRP1

3.19e-04791266gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_100

CNTNAP4 HOXA13

3.28e-0422262gudmap_developingLowerUrinaryTract_e14.5_ urethra_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_200

FOXA3 CSRP3 FOXD1

3.58e-04114263gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_200_k3
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

ANO4 ADAMTS5 FBN2 FOXD1

3.92e-04288264gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_100

CNTNAP4 HOXA13

4.25e-0425262DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_500

CNTNAP4 HOXA13 ADAMTS5

4.91e-04127263DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#1_top-relative-expression-ranked_200

CNTNAP4 HOXA13

4.97e-0427262DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k1_200
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_100

ANO4 FOXD1

5.34e-0428262gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100_k3
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#4_top-relative-expression-ranked_1000

ADAMTS5 FOXD1 CSRP1

6.00e-04136263gudmap_kidney_adult_RenalCapsule_k4_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#3_top-relative-expression-ranked_100

CNTNAP4 HOXA13

7.44e-0433262gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_200

CNTNAP4 HOXA13

8.37e-0435262DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_200
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_200

ANO4 FOXD1 CSRP1

9.61e-04160263gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_200

FOXA3 CSRP3 FOXD1

9.96e-04162263gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_200
CoexpressionAtlasJC_iEC_top-relative-expression-ranked_1000_k-means-cluster#5

ANO4 FBN2 HOXD11 FOXD1

1.00e-03370264JC_iEC_1000_K5
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

NKX2-3 CNTNAP4 HOXA13 NKX2-5 OTX1 HOXD11

1.05e-03992266PCBC_EB_blastocyst_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_200

FBN2 HOXD11 FOXD1

1.07e-03166263gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_200

CNTNAP4 HOXA13 PHOX2A

1.09e-03167263gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3 IRX4

6.70e-06177314692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3 IRX4

6.70e-06177314c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 FBN2 CSRP3 IRX4

6.86e-061783145fc9f41609735b972a2cd0830182d13742cd5bf5
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 FBN2 CSRP1 CSRP2

9.43e-06193314146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ANO4 ADAMTS5 CSRP1 CSRP2

9.82e-061953144dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-10|TCGA-Bladder / Sample_Type by Project: Shred V9

KRTAP8-1 KRTAP13-3 KRTAP19-3

9.76e-051293136a201c6344a015e5cf2f79ccf397fd7ad66b6768
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

KRTAP8-1 KRTAP19-5 KRTAP19-3

1.41e-04146313522c32103c24fc26836bb5b642083904682d9292
ToppCellfacs-Heart-LA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3

2.05e-04166313c43aec09578975df8984886993d15b42a10190c8
ToppCellfacs-Heart-LA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3

2.05e-04166313829a8998ce68739a58202851afd73e049ab0f84f
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NKX2-5 ADAMTS5 CSRP3

2.05e-04166313390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NKX2-5 ADAMTS5 CSRP3

2.05e-041663139a341dc7b756252caeaac1e934384911c880a634
ToppCellTCGA-Pancreas|World / Sample_Type by Project: Shred V9

NKX2-3 PLA2G1B FOXA3

2.13e-04168313279d5fcf9bd3f56ab560e37eed6fb3bd57dd93de
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NKX2-5 ADAMTS5 CSRP3

2.44e-041763134ed73c73972334f6dc4229920205547823252fa0
ToppCellAT1-AT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS5 FBN2 CSRP2

2.61e-041803133c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLA2G1B FOXA3 FOXD1

2.61e-04180313d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCellwk_15-18-Mesenchymal-Chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FBN2 FOXA3 FOXD1

2.65e-041813138950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

IRX4 CSRP1 CSRP2

2.65e-0418131333938e6521712058312879f84f4ae381c2bfc379
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 CSRP1 CSRP2

2.65e-04181313beb2771820956be8b190c0088ae3c4efdb53c897
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 CSRP3 IRX4

2.69e-04182313c4a7007c864a9455a7e7447e28ccd380878a6a0f
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 CSRP1 CSRP2

2.69e-04182313728a2152c166551ac229370c0900fe2bc426ea9b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 CSRP3 IRX4

2.69e-04182313c315d820ffad912c014ba5eac6f5fa6de1a94384
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3

2.74e-04183313905e1e9be0f15be184447df04b134a6aa8279074
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NKX2-6 FBN2 CSRP2

2.74e-041833134060d979948e1dd7507977629a7fbdfa4ca65bb6
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3

2.74e-0418331392eed783347a372b850de3189e72525082390014
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NKX2-6 FBN2 CSRP2

2.74e-041833130d44a978221cf3f733704bf11863502805fba733
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 FBN2 CSRP1

2.74e-04183313af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

2.74e-0418331361a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO4 FBN2 RBMXL3

2.74e-041833137961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

2.74e-041833136b5eef96b28911c752a8b6c0975918c4572cec38
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FBN2 CSRP1 CSRP2

2.78e-0418431339168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 FBN2 CSRP2

2.82e-0418531301bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3

2.82e-041853139ef66bf63ed728cbf3044520a2a1625a9d5863a4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 UQCRFS1 CSRP3

2.82e-041853132148b78db2afaf29b01d604d314d6061179e2663
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 IRX4 FOXD1

2.82e-04185313872720275789d249c9859de825a923803d458875
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS5 FBN2 FOXD1

2.87e-04186313c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PHOX2A ADAMTS5 CSRP2

2.87e-041863130c477016c1b539b3086a8066c3c6443f08c222a3
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

2.92e-04187313e1b41560c26795a7d353b9468b1bb6fc7c6b379e
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 ADAMTS5 CSRP1

2.96e-04188313c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANO4 ADAMTS5 CSRP2

2.96e-041883134d1e5f85342ae550086609d7680e32730b78b5d2
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 FBN2 CSRP2

2.96e-04188313e54e09d34e263d5709c337914809e61e74e20591
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ANO4 ADAMTS5 CSRP2

2.96e-04188313f54b063025d80de631382bf5326bc40aab7f7d00
ToppCelldroplet-Fat-Scat-21m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS5 FBN2 CSRP2

2.96e-041883137fc9810ab14354cb512e2b1285562009c10203f5
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

2.96e-04188313879de94924de978478696fc7838e05a4d795b905
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

3.01e-04189313ab7ece0a517499b70b7754720d3e434765363af6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANO4 ADAMTS5 CSRP2

3.05e-04190313938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 CSRP1 CSRP2

3.05e-04190313c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ANO4 ADAMTS5 CSRP2

3.05e-04190313645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 CSRP3 IRX4

3.10e-041913139d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-5 CSRP3 IRX4

3.10e-04191313543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 CSRP1 CSRP2

3.15e-04192313d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UQCRFS1 FOXA3 CSRP1

3.20e-04193313264785a88583fd4bbb2ed2e9a7a78bbed539e0ed
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXD11 CSRP1 CSRP2

3.20e-041933130256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS5 CSRP1 CSRP2

3.20e-041933133316d6a39abb6a518d45b846254325fc7a8b2035
ToppCellE15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS5 CSRP1 CSRP2

3.20e-04193313e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCellE12.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS5 CSRP1 CSRP2

3.30e-04195313bff7685784688425bebd78b0f284a6d4475a9415
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|tumor_Lung / Location, Cell class and cell subclass

ADAMTS5 CSRP1 CSRP2

3.30e-04195313ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCellE12.5-Mesenchymal-myocytic_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS5 CSRP1 CSRP2

3.30e-04195313aed243418cdb5df4563a7b935c1ecbd744590901
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

3.30e-04195313eb2003d4f15cad213d17eda8ab7479f5a0c62164
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

3.30e-0419531344f67437ea65d530133a0240b17f9860d9cc0e99
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 CSRP1 CSRP2

3.34e-0419631320dc9b25ecc23b6e6e52bbab8b5a404f3245ca37
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBN2 IRX4 CSRP1

3.34e-04196313a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO4 CNTNAP4 CSRP1

3.34e-0419631377feb22fd0b0b1df03375da472134412e9e69c90
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

NKX2-5 UQCRFS1 CSRP3

3.40e-0419731344e49943d62bfe622b40ad0460093d31540544df
ToppCell5'-GW_trimst-1.5-LargeIntestine|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 HOXD11 CSRP2

3.40e-041973130b2ad6a933ff1a325649cc8f139380fd158a1d42
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBN2 IRX4 CSRP1

3.40e-04197313f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO4 CNTNAP4 CSRP1

3.40e-04197313032ccc91e604113da9bc34a6f9ddb1d45dea1892
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO4 CNTNAP4 CSRP1

3.40e-0419731354fb207638e211f8efdb13003ae62a6b1f003b09
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 ADAMTS5 HOXD11

3.40e-04197313ad6c200a193a15360d17463e18a465ce1b90b8da
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANO4 NKX2-3 FBN2

3.40e-041973132e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 HOXD11 CSRP2

3.40e-04197313c7b33d64e5cba3a8fc6f2d6aa85ebc83893195de
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

ADAMTS5 CSRP1 CSRP2

3.45e-04198313f540f464118edc0fb809ebcb813d0302e6952253
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAMTS5 CSRP1 CSRP2

3.45e-041983132d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCell3'-GW_trimst-1-LargeIntestine|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 HOXD11 CSRP2

3.45e-04198313ea6621a148a96c8ffa1a93a35c9e288545d2637a
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANO4 NKX2-3 FBN2

3.45e-041983134a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 ADAMTS5 FBN2

3.50e-04199313e78f661b40da34768469549b6e755d330be6bbd8
ToppCell18-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

ANO4 ADAMTS5 CSRP1

3.50e-041993139dd130c041beaa319727f9d22b3f45ba0da49487
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 FBN2 CSRP1

3.50e-0419931336c1deac7ef0f9ebde6b2f7a63f7daa03d8c139a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 HOXD11 CSRP1

3.50e-041993133d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

ANO4 ADAMTS5 CSRP1

3.55e-04200313593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANO4 ADAMTS5 CSRP1

3.55e-042003138988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANO4 ADAMTS5 CSRP1

3.55e-0420031387827041663013f5e7273168dc8709d69840e7ce
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 ADAMTS5 FBN2

3.55e-042003133dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

ANO4 ADAMTS5 CSRP1

3.55e-04200313c5e051f1aac8dda376c342a9932785a23450e073
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS5 CSRP1 CSRP2

3.55e-042003135c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 ADAMTS5 FBN2

3.55e-04200313ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellproximal-mesenchymal-Vascular_Smooth_Muscle|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS5 CSRP1 CSRP2

3.55e-0420031322892afca3666e944102c231b3f10340d8391364
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

ANO4 ADAMTS5 CSRP1

3.55e-0420031302cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANO4 ADAMTS5 CSRP1

3.55e-04200313dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellproximal-3-mesenchymal-Vascular_Smooth_Muscle|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS5 CSRP1 CSRP2

3.55e-04200313870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO4 CNTNAP4 CSRP1

3.55e-04200313829978708463a7459fe1041bd90196775bc4b531
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Efna5_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PHOX2A NKX2-6

6.43e-045431213431c23a110070a11de41773233a8d6583d902c
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Efna5_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PHOX2A NKX2-6

6.43e-0454312cd64ee5c47df5dba0cea954cb115a8de0efb55d1
DiseaseConotruncal heart malformations

NKX2-5 NKX2-6

4.83e-064272cv:C1857586
DiseaseCONOTRUNCAL HEART MALFORMATIONS

NKX2-5 NKX2-6

4.83e-064272217095
DiseaseCONOTRUNCAL HEART MALFORMATIONS (disorder)

NKX2-5 NKX2-6

1.21e-056272C1857586
DiseaseVentricular Septal Defects

NKX2-5 IRX4

2.25e-058272C0018818
Diseaseventricular septal defect (is_implicated_in)

NKX2-5 NKX2-6

7.29e-0514272DOID:1657 (is_implicated_in)
DiseaseTetralogy of Fallot

NKX2-5 NKX2-6

9.60e-0516272C0039685
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

NKX2-5 NKX2-6

1.84e-0422272C1843687
Diseaseunipolar depression, information processing speed, cognitive function measurement

ADAMTS5 TSPOAP1

8.50e-0447272EFO_0003761, EFO_0004363, EFO_0008354
Diseaseexecutive function measurement, unipolar depression, cognitive function measurement

NKX2-3 ADAMTS5

1.00e-0351272EFO_0003761, EFO_0008354, EFO_0009332
Diseasediabetes mellitus

ANO4 MYCBP2

1.77e-0368272EFO_0000400

Protein segments in the cluster

PeptideGeneStartEntry
YSGGGKVGYLVYAGG

ADAMTS5

81

Q9UNA0
GPEQIYSGGTYYFGG

CNTNAP4

481

Q9C0A0
YSGGTYYFGGCPDKS

CNTNAP4

486

Q9C0A0
YAYKYGPCAGQGEAG

ANO4

801

Q32M45
YSCYGGYSGAPYGAG

NKX2-6

241

A6NCS4
GYSGAPYGAGYGTCY

NKX2-6

246

A6NCS4
PYGAGYGTCYAGAPS

NKX2-6

251

A6NCS4
FYQGEGGGRTGYIPC

TSPOAP1

1671

O95153
PHAYGYGPYGCGYGL

FOXD1

266

Q16676
PYGGSQGYGNYVTYG

IRX4

76

P78413
GSGFGGYGYGCYRPS

KRTAP19-3

56

Q7Z4W3
YGSGFGGYGYRSCRP

KRTAP19-5

46

Q3LI72
CYGKKYGPKGYGYGQ

CSRP1

61

P21291
YGPKGYGYGQGAGTL

CSRP1

66

P21291
NAYPAYPGYGGAACS

NKX2-5

251

P52952
YPGYGGAACSPGYSC

NKX2-5

256

P52952
YPMSYGQGGSYGQGY

OTX1

221

P32242
CYGKKYGPKGYGYGQ

CSRP2

61

Q16527
YGPKGYGYGQGAGTL

CSRP2

66

Q16527
GGGGAGGYAPYYAAA

HOXD11

96

P31277
WGSYGYPLGYSVGCG

KRTAP8-1

16

Q8IUC2
SVGCGYGSTYSPVGY

KRTAP8-1

26

Q8IUC2
SPVGYGFGYGYNGCG

KRTAP8-1

36

Q8IUC2
GGYLHYPGSSCGSSY

KRTAP13-3

16

Q3SY46
YGGYGFSCCRPLYYG

KRTAP19-8

41

Q3LI54
NYHGGQGYAKGGLGC

KRTAP22-1

6

Q3MIV0
GYGGGYLAPGYCAQT

FIGNL2

161

A6NMB9
GYLCGCPPGYYRVGQ

FBN2

2716

P35556
CYGRRYGPKGIGYGQ

CSRP3

61

P50461
AYSSSYGCAYPAGGG

NKX2-3

286

Q8TAU0
AYGPQGNGCFSQGYY

RTP5

491

Q14D33
GYGAEGGEPGVYYQG

FOXA3

326

P55318
YGGVSGLYDFGPVGC

GARS1

141

P41250
PGCGRYAGGQGYNSI

MYCBP2

3261

O75592
NYGCYCGLGGSGTPV

PLA2G1B

46

P04054
YGYFGSGYYPCARMG

HOXA13

171

P31271
GCVPIANAGDFGGYY

UQCRFS1

221

P47985
PSYGGGCRYEEYQGN

RBMXL3

321

Q8N7X1
YGDFGACSQPGGFQY

PHOX2A

21

O14813
GPGCYFSDGYGLAYD

PIFO

46

Q8TCI5