Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	triplex DNA binding	DDX12P DDX11 DDX11L8	9.54e-07	4	125	3	GO:0045142
GeneOntologyMolecularFunction	5'-3' DNA helicase activity	DDX12P DDX11 DDX11L8	3.81e-05	11	125	3	GO:0043139
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA3 PLXNB2 PLXNB3	5.06e-05	12	125	3	GO:0017154
GeneOntologyMolecularFunction	G-quadruplex DNA binding	DDX12P DDX11 DDX11L8	8.29e-05	14	125	3	GO:0051880
GeneOntologyMolecularFunction	DNA replication origin binding	DDX12P DDX11 DDX11L8	1.82e-04	18	125	3	GO:0003688
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	SELP DCHS2 PLXNB2 ITGB1 PTPRT PCDH17 TGFBR2 CELSR3 PKD1 DSG4 ROBO3 UNC5D PLXNB3	5.36e-08	313	124	13	GO:0098742
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	DCHS2 PLXNB2 ITGB1 PTPRT PCDH17 CELSR3 PKD1 DSG4 ROBO3 PLXNB3	1.97e-07	187	124	10	GO:0007156
GeneOntologyBiologicalProcess	axonogenesis	PLXNA3 HSPG2 MYCBP2 CNTNAP1 LAMA1 APLP1 PLXNB2 ITGB1 ACTR3 CYFIP1 CELSR3 ROBO3 UNC5D PLXNB3	7.98e-06	566	124	14	GO:0007409
GeneOntologyBiologicalProcess	cell-cell adhesion	SELP DCHS2 FNDC3A NPHP4 PLXNB2 ITGB1 PTPRT PCDH17 STAT5A STAT5B TGFBR2 CELSR3 PKD1 TMEM131L DSG4 DUSP10 ROBO3 UNC5D PLXNB3	2.31e-05	1077	124	19	GO:0098609
GeneOntologyBiologicalProcess	axon development	PLXNA3 HSPG2 MYCBP2 CNTNAP1 LAMA1 APLP1 PLXNB2 ITGB1 ACTR3 CYFIP1 CELSR3 ROBO3 UNC5D PLXNB3	3.23e-05	642	124	14	GO:0061564
GeneOntologyBiologicalProcess	establishment of sister chromatid cohesion	DDX12P DDX11 DDX11L8	3.38e-05	11	124	3	GO:0034085
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	PLXNA3 HSPG2 MYCBP2 CNTNAP1 LAMA1 APLP1 PLXNB2 ITGB1 ACTR3 CYFIP1 CELSR3 ROBO3 UNC5D PLXNB3 STRCP1	4.36e-05	748	124	15	GO:0048667
GeneOntologyBiologicalProcess	cell morphogenesis	PLXNA3 HSPG2 FLNB MYCBP2 CNTNAP1 LAMA1 APLP1 PLXNB2 ITGB1 ACTR3 CYFIP1 CELSR3 SH3D19 MAEL ROBO3 UNC5D PLXNB3 ARAP1 STRCP1	9.27e-05	1194	124	19	GO:0000902
GeneOntologyBiologicalProcess	development of secondary male sexual characteristics	STAT5A STAT5B	1.07e-04	3	124	2	GO:0046544
GeneOntologyCellularComponent	Ctf18 RFC-like complex	DDX12P DDX11 DDX11L8	2.43e-05	10	125	3	GO:0031390
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA3 PLXNB2 PLXNB3	5.71e-05	13	125	3	GO:0002116
GeneOntologyCellularComponent	basement membrane	HSPG2 COL7A1 FRAS1 LAMA1 APLP1 ITGB1	9.30e-05	122	125	6	GO:0005604
GeneOntologyCellularComponent	extracellular matrix	HSPG2 COL7A1 FRAS1 VWF LAMA1 APLP1 PLXNB2 ITGB1 IGFBPL1 LINGO1 LRIG1 HPX	5.75e-04	656	125	12	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	HSPG2 COL7A1 FRAS1 VWF LAMA1 APLP1 PLXNB2 ITGB1 IGFBPL1 LINGO1 LRIG1 HPX	5.90e-04	658	125	12	GO:0030312
GeneOntologyCellularComponent	receptor complex	PLXNA3 PLXNB2 ITGB1 ITPR2 MST1R TGFBR2 AHRR IGHD P2RX6 MUSK PLXNB3	7.40e-04	581	125	11	GO:0043235
MousePheno	increased allantois apoptosis	DDX12P DDX11 DDX11L8	1.82e-05	8	98	3	MP:0003891
MousePheno	absent paraxial mesoderm	DDX12P DDX11 DDX11L8	2.72e-05	9	98	3	MP:0012184
MousePheno	kinked neural tube	DDX12P ITGB1 DDX11 CYFIP1 DDX11L8	4.79e-05	57	98	5	MP:0003400
MousePheno	decreased diameter of ulna	FLNB LGI4	4.86e-05	2	98	2	MP:0008157
MousePheno	decreased paraxial mesoderm size	DDX12P DDX11 DDX11L8	7.02e-05	12	98	3	MP:0012183
MousePheno	wavy neural tube	DDX12P ITGB1 DDX11 DDX11L8	1.26e-04	37	98	4	MP:0000930
MousePheno	abnormal neuron differentiation	PLXNA3 HSPG2 MYCBP2 PLXNB2 PTPRT CELSR3 ROBO3 UNC5D MUSK	1.32e-04	275	98	9	MP:0009937
MousePheno	decreased diameter of radius	FLNB LGI4	1.45e-04	3	98	2	MP:0008155
MousePheno	small allantois	DDX12P DDX11 DDX11L8	1.75e-04	16	98	3	MP:0004559
MousePheno	open neural tube	DDX12P PLXNB2 ITGB1 DDX11 MED24 CYFIP1 PKD1 DDX11L8	1.86e-04	226	98	8	MP:0000929
Domain	Ig-like_fold	PLXNA3 HSPG2 FLNB COL7A1 MYCBP2 FNDC3A PLXNB2 SIGLEC15 IGFBPL1 PTPRT MST1R LINGO1 LRIG1 IGHD ROBO3 TAPBP UNC5D MUSK PLXNB3	1.37e-07	706	121	19	IPR013783
Domain	-	PLXNA3 HSPG2 FLNB COL7A1 MYCBP2 FNDC3A PLXNB2 SIGLEC15 IGFBPL1 PTPRT MST1R LINGO1 LRIG1 ROBO3 TAPBP UNC5D MUSK PLXNB3	2.67e-07	663	121	18	2.60.40.10
Domain	PSI	PLXNA3 PLXNB2 ITGB1 MST1R PLXNB3	9.32e-06	44	121	5	IPR016201
Domain	PSI	PLXNA3 PLXNB2 ITGB1 MST1R PLXNB3	1.16e-05	46	121	5	SM00423
Domain	Plexin_cytopl	PLXNA3 PLXNB2 PLXNB3	2.17e-05	9	121	3	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNB2 PLXNB3	2.17e-05	9	121	3	IPR013548
Domain	Plexin	PLXNA3 PLXNB2 PLXNB3	2.17e-05	9	121	3	IPR031148
Domain	IPT	PLXNA3 PLXNB2 MST1R PLXNB3	2.62e-05	27	121	4	SM00429
Domain	Semap_dom	PLXNA3 PLXNB2 MST1R PLXNB3	4.61e-05	31	121	4	IPR001627
Domain	SEMA	PLXNA3 PLXNB2 MST1R PLXNB3	4.61e-05	31	121	4	PS51004
Domain	TIG	PLXNA3 PLXNB2 MST1R PLXNB3	4.61e-05	31	121	4	PF01833
Domain	Sema	PLXNA3 PLXNB2 MST1R PLXNB3	4.61e-05	31	121	4	SM00630
Domain	Sema	PLXNA3 PLXNB2 MST1R PLXNB3	4.61e-05	31	121	4	PF01403
Domain	IPT	PLXNA3 PLXNB2 MST1R PLXNB3	5.24e-05	32	121	4	IPR002909
Domain	Plexin_repeat	PLXNA3 PLXNB2 MST1R PLXNB3	5.24e-05	32	121	4	IPR002165
Domain	PSI	PLXNA3 PLXNB2 MST1R PLXNB3	5.24e-05	32	121	4	PF01437
Domain	Ig_E-set	PLXNA3 FLNB MYCBP2 PLXNB2 MST1R PLXNB3	5.90e-05	104	121	6	IPR014756
Domain	ConA-like_dom	HSPG2 CNTNAP1 LAMA1 PTPRT TRIM11 CELSR3 TRIM50 NEURL4	9.09e-05	219	121	8	IPR013320
Domain	LAM_G_DOMAIN	HSPG2 CNTNAP1 LAMA1 CELSR3	1.04e-04	38	121	4	PS50025
Domain	Laminin_G_2	HSPG2 CNTNAP1 LAMA1 CELSR3	1.28e-04	40	121	4	PF02210
Domain	LamG	HSPG2 CNTNAP1 LAMA1 CELSR3	1.86e-04	44	121	4	SM00282
Domain	Ig_I-set	HSPG2 IGFBPL1 LINGO1 LRIG1 ROBO3 UNC5D MUSK	2.40e-04	190	121	7	IPR013098
Domain	I-set	HSPG2 IGFBPL1 LINGO1 LRIG1 ROBO3 UNC5D MUSK	2.40e-04	190	121	7	PF07679
Domain	LDLRA_1	HSPG2 LRP10 PKD1 LDLRAD4	2.62e-04	48	121	4	PS01209
Domain	LDLRA_2	HSPG2 LRP10 PKD1 LDLRAD4	2.83e-04	49	121	4	PS50068
Domain	IG_LIKE	HSPG2 SIGLEC15 IGFBPL1 PTPRT LINGO1 LRIG1 IGHD ROBO3 TAPBP UNC5D MUSK	3.51e-04	491	121	11	PS50835
Domain	Sushi	SELP SUSD6 CSMD2 C4BPB	3.57e-04	52	121	4	PF00084
Domain	CCP	SELP SUSD6 CSMD2 C4BPB	4.13e-04	54	121	4	SM00032
Domain	Ig-like_dom	HSPG2 SIGLEC15 IGFBPL1 PTPRT LINGO1 LRIG1 IGHD ROBO3 TAPBP UNC5D MUSK	4.30e-04	503	121	11	IPR007110
Domain	SUSHI	SELP SUSD6 CSMD2 C4BPB	4.75e-04	56	121	4	PS50923
Domain	Sushi_SCR_CCP_dom	SELP SUSD6 CSMD2 C4BPB	5.08e-04	57	121	4	IPR000436
Domain	Laminin_G	HSPG2 CNTNAP1 LAMA1 CELSR3	5.43e-04	58	121	4	IPR001791
Domain	EGF	SELP HSPG2 FRAS1 CNTNAP1 LAMA1 THBD CELSR3	8.56e-04	235	121	7	SM00181
Domain	IGc2	HSPG2 IGFBPL1 LINGO1 LRIG1 ROBO3 UNC5D MUSK	8.56e-04	235	121	7	SM00408
Domain	Ig_sub2	HSPG2 IGFBPL1 LINGO1 LRIG1 ROBO3 UNC5D MUSK	8.56e-04	235	121	7	IPR003598
Domain	STAT_TF_DNA-bd_sub	STAT5A STAT5B	8.56e-04	7	121	2	IPR012345
Domain	STAT	STAT5A STAT5B	8.56e-04	7	121	2	IPR001217
Domain	APC_su10/DOC_dom	MYCBP2 CUL9	8.56e-04	7	121	2	IPR004939
Domain	STAT_int	STAT5A STAT5B	8.56e-04	7	121	2	SM00964
Domain	STAT_TF_DNA-bd	STAT5A STAT5B	8.56e-04	7	121	2	IPR013801
Domain	STAT_bind	STAT5A STAT5B	8.56e-04	7	121	2	PF02864
Domain	STAT_int	STAT5A STAT5B	8.56e-04	7	121	2	PF02865
Domain	DOC	MYCBP2 CUL9	8.56e-04	7	121	2	PS51284
Domain	-	STAT5A STAT5B	8.56e-04	7	121	2	1.10.532.10
Domain	STAT_alpha	STAT5A STAT5B	8.56e-04	7	121	2	PF01017
Domain	-	STAT5A STAT5B	8.56e-04	7	121	2	1.20.1050.20
Domain	ANAPC10	MYCBP2 CUL9	8.56e-04	7	121	2	PF03256
Domain	STAT_TF_prot_interaction	STAT5A STAT5B	8.56e-04	7	121	2	IPR013799
Domain	STAT_TF_coiled-coil	STAT5A STAT5B	8.56e-04	7	121	2	IPR015988
Domain	-	STAT5A STAT5B	8.56e-04	7	121	2	2.60.40.630
Domain	APC10	MYCBP2 CUL9	8.56e-04	7	121	2	SM01337
Domain	EGF_LAM_2	HSPG2 LAMA1 CELSR3	9.48e-04	30	121	3	PS50027
Domain	EGF_LAM_1	HSPG2 LAMA1 CELSR3	9.48e-04	30	121	3	PS01248
Domain	STAT_TF_alpha	STAT5A STAT5B	1.14e-03	8	121	2	IPR013800
Domain	LAMININ_IVA	HSPG2 LAMA1	1.14e-03	8	121	2	PS51115
Domain	Laminin_B	HSPG2 LAMA1	1.14e-03	8	121	2	PF00052
Domain	LamB	HSPG2 LAMA1	1.14e-03	8	121	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA1	1.14e-03	8	121	2	IPR000034
Domain	EGF-like_dom	SELP HSPG2 FRAS1 CNTNAP1 LAMA1 THBD CELSR3	1.20e-03	249	121	7	IPR000742
Domain	EGF_1	SELP HSPG2 CNTNAP1 LAMA1 ITGB1 THBD CELSR3	1.37e-03	255	121	7	PS00022
Domain	EGF	SELP HSPG2 CNTNAP1 THBD CELSR3	1.37e-03	126	121	5	PF00008
Domain	EGF_Lam	HSPG2 LAMA1 CELSR3	1.49e-03	35	121	3	SM00180
Domain	Laminin_EGF	HSPG2 LAMA1 CELSR3	1.49e-03	35	121	3	PF00053
Domain	EGF-like_CS	SELP HSPG2 CNTNAP1 LAMA1 ITGB1 THBD CELSR3	1.57e-03	261	121	7	IPR013032
Domain	IG	HSPG2 SIGLEC15 IGFBPL1 PTPRT LINGO1 LRIG1 ROBO3 UNC5D MUSK	1.69e-03	421	121	9	SM00409
Domain	Ig_sub	HSPG2 SIGLEC15 IGFBPL1 PTPRT LINGO1 LRIG1 ROBO3 UNC5D MUSK	1.69e-03	421	121	9	IPR003599
Domain	Laminin_EGF	HSPG2 LAMA1 CELSR3	1.90e-03	38	121	3	IPR002049
Domain	LDLR_class-A_CS	HSPG2 LRP10 LDLRAD4	2.20e-03	40	121	3	IPR023415
Domain	Filamin	FLNB MYCBP2	2.20e-03	11	121	2	PF00630
Domain	FILAMIN_REPEAT	FLNB MYCBP2	2.20e-03	11	121	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB MYCBP2	2.20e-03	11	121	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB MYCBP2	2.20e-03	11	121	2	IPR017868
Domain	Laminin_G_1	HSPG2 LAMA1	2.20e-03	11	121	2	PF00054
Domain	Rho_GTPase_activation_prot	PLXNA3 PLXNB2 PLXNB3 ARAP1	2.57e-03	88	121	4	IPR008936
Domain	Cys-rich_flank_reg_C	LGI4 LINGO1 LRIG1 PKD1	2.79e-03	90	121	4	IPR000483
Domain	LRRCT	LGI4 LINGO1 LRIG1 PKD1	2.79e-03	90	121	4	SM00082
Domain	Ldl_recept_a	HSPG2 LRP10 LDLRAD4	3.09e-03	45	121	3	PF00057
Domain	Galactose-bd-like	MYCBP2 CNTNAP1 LAMA1 CUL9	3.26e-03	94	121	4	IPR008979
Domain	-	HSPG2 LRP10 LDLRAD4	3.29e-03	46	121	3	4.10.400.10
Domain	-	HSPG2 CNTNAP1 LAMA1 CELSR3	3.39e-03	95	121	4	2.60.120.200
Domain	Growth_fac_rcpt_	HSPG2 FRAS1 LAMA1 IGFBPL1 THBD	3.48e-03	156	121	5	IPR009030
Domain	LDrepeatLR_classA_rpt	HSPG2 LRP10 LDLRAD4	3.93e-03	49	121	3	IPR002172
Domain	LDLa	HSPG2 LRP10 LDLRAD4	3.93e-03	49	121	3	SM00192
Domain	zf-RING_2	RNF130 MYCBP2 PJA2	4.65e-03	52	121	3	PF13639
Domain	-	PLXNA3 PLXNB2	4.71e-03	16	121	2	1.10.506.10
Domain	Cadherin_CS	DCHS2 PCDH17 CELSR3 DSG4	5.53e-03	109	121	4	IPR020894
Domain	RasGAP_dom	PLXNA3 PLXNB2	5.95e-03	18	121	2	IPR001936
Domain	CADHERIN_1	DCHS2 PCDH17 CELSR3 DSG4	6.27e-03	113	121	4	PS00232
Domain	Cadherin	DCHS2 PCDH17 CELSR3 DSG4	6.27e-03	113	121	4	PF00028
Domain	CADHERIN_2	DCHS2 PCDH17 CELSR3 DSG4	6.47e-03	114	121	4	PS50268
Domain	-	DCHS2 PCDH17 CELSR3 DSG4	6.47e-03	114	121	4	2.60.40.60
Pathway	REACTOME_LAMININ_INTERACTIONS	HSPG2 COL7A1 LAMA1 ITGB1	3.75e-05	30	90	4	M27216
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 PLXNA3 PRKD2 HSPG2 FRAS1 ZNF628 MYCBP2 C15orf39 CUL9 NPHP4 PLXNB2 ITPR2 FZD7 MST1R CELSR3 MARK4 PKD1 SLC45A1 ELL ARAP1	3.25e-09	1105	126	20	35748872
Pubmed	STAT5 drives abnormal proliferation in autosomal dominant polycystic kidney disease.	STAT5A STAT5B PKD1	4.64e-08	3	126	3	28104302
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX12P DDX11 DDX11L8	4.64e-08	3	126	3	17611414
Pubmed	Mammalian ChlR1 has a role in heterochromatin organization.	DDX12P DDX11 DDX11L8	4.64e-08	3	126	3	21854770
Pubmed	The expression of von Willebrand factor, soluble thrombomodulin, and soluble p-selectin during orthotopic liver transplantation.	SELP VWF THBD	4.64e-08	3	126	3	17275499
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	HSPG2 COL7A1 FRAS1 LAMA1 ITGB1	6.38e-08	29	126	5	22613833
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PLXNA3 HSPG2 COL7A1 FRAS1 MYCBP2 SUSD6 CNTNAP1 LAMA1 PLXNB2 ITGB1 ITPR2 MST1R PDF CELSR3 LRP10 FAM3A TMEM131L TAPBP	3.55e-07	1201	126	18	35696571
Pubmed	The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan.	HSPG2 LAMA1 ITGB1	4.62e-07	5	126	3	9688542
Pubmed	Interplay between scatter factor receptors and B plexins controls invasive growth.	PLXNB2 MST1R PLXNB3	4.62e-07	5	126	3	15184888
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA3 PLXNB2 PLXNB3	2.57e-06	8	126	3	15661641
Pubmed	The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.	DDX12P DDX11 DDX11L8	2.57e-06	8	126	3	22678773
Pubmed	Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.	COL7A1 LAMA1 ITGB1	2.57e-06	8	126	3	19651211
Pubmed	Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.	HSPG2 LAMA1 ITGB1	5.47e-06	10	126	3	16554364
Pubmed	Synergistic activities of alpha3 and alpha6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse.	HSPG2 LAMA1 ITGB1	9.97e-06	12	126	3	10433923
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA3 PLXNB2 PLXNB3	9.97e-06	12	126	3	21270798
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA3 PLXNB2 PLXNB3	1.29e-05	13	126	3	10520995
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	MYCBP2 CUL9 ITPR2 PJA2 CYFIP1 MAP7D2 NEURL4	1.29e-05	212	126	7	33853758
Pubmed	Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.	STAT5A STAT5B	1.30e-05	2	126	2	23151802
Pubmed	Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.	STAT5A STAT5B	1.30e-05	2	126	2	26999798
Pubmed	Inactivation of integrin-β1 prevents the development of polycystic kidney disease after the loss of polycystin-1.	ITGB1 PKD1	1.30e-05	2	126	2	25145933
Pubmed	A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.	STAT5A STAT5B	1.30e-05	2	126	2	31443474
Pubmed	Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.	STAT5A STAT5B	1.30e-05	2	126	2	12377952
Pubmed	Activation of beta1 integrins on blood eosinophils by P-selectin.	SELP ITGB1	1.30e-05	2	126	2	21441381
Pubmed	A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.	STAT5A STAT5B	1.30e-05	2	126	2	21127177
Pubmed	The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.	STAT5A STAT5B	1.30e-05	2	126	2	16289657
Pubmed	Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.	STAT5A STAT5B	1.30e-05	2	126	2	25552366
Pubmed	Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.	STAT5A STAT5B	1.30e-05	2	126	2	25470773
Pubmed	Constitutively active Stat5A and Stat5B promote adipogenesis.	STAT5A STAT5B	1.30e-05	2	126	2	21431790
Pubmed	Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.	STAT5A STAT5B	1.30e-05	2	126	2	28500076
Pubmed	STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.	STAT5A STAT5B	1.30e-05	2	126	2	21826656
Pubmed	Thrombomodulin and von Willebrand factor: relation to endothelial dysfunction and disease outcome in children with acute lymphoblastic leukemia.	VWF THBD	1.30e-05	2	126	2	21150180
Pubmed	Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.	STAT5A STAT5B	1.30e-05	2	126	2	7720707
Pubmed	STAT5A and STAT5B have opposite correlations with drug response gene expression.	STAT5A STAT5B	1.30e-05	2	126	2	27264955
Pubmed	Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.	STAT5A STAT5B	1.30e-05	2	126	2	22159083
Pubmed	STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.	STAT5A STAT5B	1.30e-05	2	126	2	20008792
Pubmed	STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.	STAT5A STAT5B	1.30e-05	2	126	2	33199496
Pubmed	The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.	STAT5A STAT5B	1.30e-05	2	126	2	16502315
Pubmed	Stat5: an essential regulator of mast cell biology.	STAT5A STAT5B	1.30e-05	2	126	2	12217382
Pubmed	Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.	STAT5A STAT5B	1.30e-05	2	126	2	31599926
Pubmed	DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.	STAT5A STAT5B	1.30e-05	2	126	2	10594041
Pubmed	Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.	STAT5A STAT5B	1.30e-05	2	126	2	21036145
Pubmed	Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.	STAT5A STAT5B	1.30e-05	2	126	2	10486277
Pubmed	Prognostic value of plasma levels of thrombomodulin and von Willebrand factor in Egyptian children with acute lymphoblastic leukemia.	VWF THBD	1.30e-05	2	126	2	24243921
Pubmed	Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.	STAT5A STAT5B	1.30e-05	2	126	2	16840779
Pubmed	The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.	STAT5A STAT5B	1.30e-05	2	126	2	15128421
Pubmed	STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.	STAT5A STAT5B	1.30e-05	2	126	2	30377054
Pubmed	Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.	STAT5A STAT5B	1.30e-05	2	126	2	23565285
Pubmed	Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.	STAT5A STAT5B	1.30e-05	2	126	2	32790723
Pubmed	In vivo identification of novel STAT5 target genes.	STAT5A STAT5B	1.30e-05	2	126	2	18492722
Pubmed	Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.	STAT5A STAT5B	1.30e-05	2	126	2	10066807
Pubmed	Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.	STAT5A STAT5B	1.30e-05	2	126	2	10835485
Pubmed	Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.	STAT5A STAT5B	1.30e-05	2	126	2	35464049
Pubmed	Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease.	LCN2 PKD1	1.30e-05	2	126	2	28341240
Pubmed	Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.	STAT5A STAT5B	1.30e-05	2	126	2	18286195
Pubmed	Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.	STAT5A STAT5B	1.30e-05	2	126	2	23773921
Pubmed	Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.	STAT5A STAT5B	1.30e-05	2	126	2	8631883
Pubmed	Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.	STAT5A STAT5B	1.30e-05	2	126	2	11030348
Pubmed	Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.	STAT5A STAT5B	1.30e-05	2	126	2	24878107
Pubmed	Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.	STAT5A STAT5B	1.30e-05	2	126	2	12847485
Pubmed	Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.	STAT5A STAT5B	1.30e-05	2	126	2	12835478
Pubmed	Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.	STAT5A STAT5B	1.30e-05	2	126	2	7568026
Pubmed	Identification of STAT5A and STAT5B target genes in human T cells.	STAT5A STAT5B	1.30e-05	2	126	2	24497979
Pubmed	Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.	STAT5A STAT5B	1.30e-05	2	126	2	17536022
Pubmed	STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.	STAT5A STAT5B	1.30e-05	2	126	2	17382296
Pubmed	STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.	STAT5A STAT5B	1.30e-05	2	126	2	17911616
Pubmed	STAT5 signaling in sexually dimorphic gene expression and growth patterns.	STAT5A STAT5B	1.30e-05	2	126	2	10486314
Pubmed	The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.	STAT5A STAT5B	1.30e-05	2	126	2	17599554
Pubmed	Localization of chi1-related helicase genes to human chromosome regions 12p11 and 12p13: similarity between parts of these genes and conserved human telomeric-associated DNA.	DDX12P DDX11	1.30e-05	2	126	2	8833153
Pubmed	MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.	STAT5A STAT5B	1.30e-05	2	126	2	24497923
Pubmed	Kynurenines and oxidative status are independently associated with thrombomodulin and von Willebrand factor levels in patients with end-stage renal disease.	VWF THBD	1.30e-05	2	126	2	19477487
Pubmed	Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.	STAT5A STAT5B	1.30e-05	2	126	2	24335105
Pubmed	Brain STAT5 signaling modulates learning and memory formation.	STAT5A STAT5B	1.30e-05	2	126	2	29460051
Pubmed	Differential role of von Willebrand factor and P-selectin on microvascular thrombosis in endotoxemia.	SELP VWF	1.30e-05	2	126	2	18802014
Pubmed	STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.	STAT5A STAT5B	1.30e-05	2	126	2	28606561
Pubmed	Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.	STAT5A STAT5B	1.30e-05	2	126	2	12393407
Pubmed	Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.	LCN2 PKD1	1.30e-05	2	126	2	18974761
Pubmed	The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.	STAT5A STAT5B	1.30e-05	2	126	2	12039059
Pubmed	Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse.	STAT5A STAT5B	1.30e-05	2	126	2	21178171
Pubmed	Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.	STAT5A STAT5B	1.30e-05	2	126	2	20233708
Pubmed	Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development.	STAT5A STAT5B	1.30e-05	2	126	2	16775227
Pubmed	STAT5 isoforms: controversies and clarifications.	STAT5A STAT5B	1.30e-05	2	126	2	17447893
Pubmed	Insight into interactions of the von-Willebrand-factor-A-like domain 2 with the FNIII-like domain 9 of collagen VII by NMR and SPR.	COL7A1 VWF	1.30e-05	2	126	2	21570975
Pubmed	Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.	STAT5A STAT5B	1.30e-05	2	126	2	16115927
Pubmed	Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.	STAT5A STAT5B	1.30e-05	2	126	2	23275557
Pubmed	Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation.	STAT5A STAT5B	1.30e-05	2	126	2	11867689
Pubmed	Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.	STAT5A STAT5B	1.30e-05	2	126	2	15980098
Pubmed	Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.	STAT5A STAT5B	1.30e-05	2	126	2	15340066
Pubmed	Increased P-selectin expression on platelets and decreased plasma thrombomodulin in Fontan patients.	SELP THBD	1.30e-05	2	126	2	19638712
Pubmed	STAT5A/B gene locus undergoes amplification during human prostate cancer progression.	STAT5A STAT5B	1.30e-05	2	126	2	23660011
Pubmed	Role of Stat5 in type I interferon-signaling and transcriptional regulation.	STAT5A STAT5B	1.30e-05	2	126	2	12901872
Pubmed	Effect of medium change on the development of in vitro matured and fertilized bovine oocytes cultured in medium containing amino acids.	FLNB ITGB1	1.30e-05	2	126	2	10676904
Pubmed	O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.	STAT5A STAT5B	1.30e-05	2	126	2	28074064
Pubmed	STAT5b: A master regulator of key biological pathways.	STAT5A STAT5B	1.30e-05	2	126	2	36755813
Pubmed	Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling.	STAT5A STAT5B	1.30e-05	2	126	2	25333863
Pubmed	A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance.	STAT5A STAT5B	1.30e-05	2	126	2	12421978
Pubmed	A single amino acid in the DNA binding regions of STAT5A and STAT5B confers distinct DNA binding specificities.	STAT5A STAT5B	1.30e-05	2	126	2	9852045
Pubmed	Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior.	STAT5A STAT5B	1.30e-05	2	126	2	19966185
Pubmed	Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.	STAT5A STAT5B	1.30e-05	2	126	2	21704724
Pubmed	Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.	DDX12P DDX11	1.30e-05	2	126	2	32855419
Pubmed	Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.	STAT5A STAT5B	1.30e-05	2	126	2	38618957
Interaction	FBXO2 interactions	PLXNA3 HSPG2 FRAS1 CNTNAP1 LAMA1 PLXNB2 ITGB1 CELSR3 LINGO1 LRIG1 LRP10 TMEM131L C4BPB TMEM39A TAPBP	2.29e-08	411	120	15	int:FBXO2
Cytoband	4q31.3	DCHS2 SH3D19 TMEM131L	8.58e-05	31	126	3	4q31.3
Cytoband	12p11	ITPR2 DDX11	2.66e-04	9	126	2	12p11
GeneFamily	Plexins	PLXNA3 PLXNB2 PLXNB3	7.96e-06	9	84	3	683
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 IGFBPL1 LINGO1 LRIG1 ROBO3 UNC5D MUSK	9.93e-06	161	84	7	593
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP SUSD6 CSMD2 C4BPB	1.42e-04	57	84	4	1179
GeneFamily	Olfactory receptors, family 11	OR11H12 OR11H1 OR11H2	1.60e-04	23	84	3	159
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP THBD PKD1	9.08e-04	41	84	3	1298
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN	OAZ2 PLXNB2 STAT5A STAT5B DDX11 TGFBR2 TMEM131L ARAP1	5.48e-06	200	125	8	M7658
Coexpression	LEE_BMP2_TARGETS_UP	RNF130 COL7A1 VWF ENPP3 LCN2 PLXNB2 ITPR2 FZD7 THBD LRIG1 LRP10 STARD9 PNPLA7 TAPBP	2.20e-05	780	125	14	M2324
Coexpression	LEE_BMP2_TARGETS_UP	RNF130 COL7A1 VWF ENPP3 LCN2 PLXNB2 ITPR2 FZD7 THBD LRIG1 LRP10 STARD9 PNPLA7 TAPBP	3.11e-05	805	125	14	MM1067
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_MID_SCHWANN_CELL	HSPG2 NIBAN1 NEK6 LRIG1 LRP10 STARD9 SH3D19 PLXNB3	4.51e-05	268	125	8	M45796
Coexpression	GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP	FLNB NIBAN1 C15orf39 PLXNB2 ARID5A CYFIP1 KCNN4	5.06e-05	200	125	7	M5994
Coexpression	GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN	SUSD6 TRIM11 LRP10 TRABD NFKBIL1 TMEM39A MAP4K2	5.06e-05	200	125	7	M7904
Coexpression	GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP	SELP NEK6 FNDC3A LCN2 STAT5A CYFIP1 LRP10	5.06e-05	200	125	7	M9614
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP	NIBAN1 NEK6 SUSD6 ITGB1 STAT5B LRIG1 DUSP10	5.06e-05	200	125	7	M6514
Coexpression	GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP	FLNB SUSD6 STAT5A STAT5B TBC1D14 KCNN4 DUSP10	5.06e-05	200	125	7	M9205
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP FLNB VWF LAMA1 IGFBPL1 PCDH17 THBD	1.27e-06	192	126	7	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP FLNB VWF LAMA1 IGFBPL1 PCDH17 THBD	1.27e-06	192	126	7	845cc9c18b4436b07dd3ce7980052683937546d2
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP FLNB VWF LAMA1 IGFBPL1 PCDH17 THBD	1.27e-06	192	126	7	c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 STARD9 MARK4	1.46e-06	196	126	7	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SELP HSPG2 FLNB VWF PCDH17 THBD MAP4K2	1.46e-06	196	126	7	81278e696d823744267d6315c4d42799c4ea0b2c
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD MAP4K2	1.51e-06	197	126	7	b18f2c14d6720f6ae8520c0800356f4a57393ad3
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	VWF CNTNAP1 ARID5A PCDH17 ITPR2 THBD LINGO1	1.61e-06	199	126	7	bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PLXNA3 COL7A1 NIBAN1 APLP1 LRIG1 HPX	2.39e-06	135	126	6	5b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LGI4 IGFBPL1 PCDH17 P2RX6 TAGLN3 KCNN4	1.13e-05	177	126	6	d1dd778d1a52305b1ea3954f81fd5364b3d57bbe
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LGI4 PLEKHB1 PCDH17 CELSR3 TAGLN3 KCNN4	1.17e-05	178	126	6	13dfd28a80889c2dacdc65b94a41bb9762dc409d
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LGI4 PLEKHB1 PCDH17 CELSR3 TAGLN3 KCNN4	1.17e-05	178	126	6	a9ba4089413b1c55d667ce836b6972ca572ee2b8
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SELP HSPG2 FLNB VWF ITPR2 APCDD1L	1.21e-05	179	126	6	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 CNTNAP1 APLP1 LGI4 MST1R LINGO1	1.29e-05	181	126	6	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 CNTNAP1 APLP1 LGI4 MST1R LINGO1	1.29e-05	181	126	6	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 CSMD2 LGI4 PCDH17 P2RX6 PLXNB3	1.29e-05	181	126	6	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	1.37e-05	183	126	6	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 VWF PCDH17 TGFBR2 STARD9 HPX	1.41e-05	184	126	6	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF130 HSPG2 APLP1 LGI4 TGFBR2 PLXNB3	1.50e-05	186	126	6	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP HSPG2 FLNB VWF PCDH17 THBD	1.50e-05	186	126	6	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF FAM178B PLEKHB1 FZD7 CYFIP1 UNG	1.60e-05	188	126	6	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB VWF LAMA1 IGFBPL1 PCDH17 THBD	1.75e-05	191	126	6	9fc674a58f20b47255e4457d5195c8cff17b0414
ToppCell	droplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB VWF LAMA1 IGFBPL1 PCDH17 THBD	1.75e-05	191	126	6	c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	SELP HSPG2 FLNB VWF PCDH17 ITPR2	1.80e-05	192	126	6	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	1.85e-05	193	126	6	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SELP HSPG2 VWF PCDH17 THBD KCNN4	1.85e-05	193	126	6	84d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP HSPG2 FLNB VWF PCDH17 THBD	1.85e-05	193	126	6	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELP HSPG2 FLNB VWF PCDH17 THBD	1.91e-05	194	126	6	f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell	15-Airway-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	SELP HSPG2 VWF PCDH17 THBD KCNN4	1.91e-05	194	126	6	ac0e48b0c09a7f57d30dff321b0c30a4c5e16ad9
ToppCell	15-Airway-Endothelial-Endothelial\|Airway / Age, Tissue, Lineage and Cell class	SELP HSPG2 VWF PCDH17 THBD KCNN4	1.91e-05	194	126	6	f3851337a2d17f4acef2cd812a766eb0b503748b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 STARD9	1.91e-05	194	126	6	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELP HSPG2 FLNB VWF PCDH17 THBD	1.91e-05	194	126	6	04b1acc2e879feafb43f75435281c5acd8d23be2
ToppCell	(6)_Endothelial-B_(Artery)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SELP HSPG2 FLNB VWF PCDH17 DDX11	1.91e-05	194	126	6	0cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 STARD9	1.91e-05	194	126	6	f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 STARD9	1.91e-05	194	126	6	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	Control-Treg\|Control / Disease condition and Cell class	SELP NIBAN1 ITGB1 KCNN4 DUSP10 LDLRAD4	1.96e-05	195	126	6	bbe9789eb2c17f43de55b2e6d01d1093c64dc666
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SELP HSPG2 FLNB VWF PCDH17 THBD	1.96e-05	195	126	6	cc3d6f98d310e8840ff497d7258c5ccf54e6c624
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 FLNB VWF PCDH17 TGFBR2	1.96e-05	195	126	6	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF TGFBR2 THBD MAP4K2	1.96e-05	195	126	6	9ad4981c4d157edc752de206ab0d754aa14beab8
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.02e-05	196	126	6	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.02e-05	196	126	6	a0ba408b802fa6d6e42e6d234b6879fdb1583f81
ToppCell	15-Distal-Endothelial-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	HSPG2 VWF PCDH17 TGFBR2 THBD MAP4K2	2.02e-05	196	126	6	fda2dd3895bf6ae39fcce2050e4878750f5f5b71
ToppCell	15-Distal-Endothelial\|Distal / Age, Tissue, Lineage and Cell class	HSPG2 VWF PCDH17 TGFBR2 THBD MAP4K2	2.02e-05	196	126	6	03245aca5cb97fd5c3f8a986efff7131ccd40e34
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF130 HSPG2 NIBAN1 LGI4 TGFBR2 PLXNB3	2.02e-05	196	126	6	e6adcfe1a00d4910e0b92848f8a80224e0d6db12
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.08e-05	197	126	6	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	3'-Child09-12-SmallIntestine-Endothelial\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.08e-05	197	126	6	86a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SELP HSPG2 VWF PCDH17 THBD MAP4K2	2.08e-05	197	126	6	88859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF TGFBR2 THBD MAP4K2	2.08e-05	197	126	6	dfc052a447c3b32235fcaffdf06c4e0941723d19
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.08e-05	197	126	6	947042f888335c0829d4d5daeb623973eadb3348
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 NIBAN1 VWF TGFBR2 THBD MAP4K2	2.14e-05	198	126	6	ff8a9adc1302a4679ccdfe9ef95ef53e4c7a5391
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.14e-05	198	126	6	5b86dc00acf8ac2ede008f5d79c09996485bf250
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SELP HSPG2 VWF ARID5A PCDH17 THBD	2.14e-05	198	126	6	f7aa809040fa9f5782b92eec1f289d690eb5c7bd
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 NIBAN1 VWF TGFBR2 THBD MAP4K2	2.14e-05	198	126	6	37d6557833877fc2ff51fbeb589e3eb832dbef5f
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.14e-05	198	126	6	13203249e5743ba2699871c184d141207e550a86
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.14e-05	198	126	6	99be7a7a84199dac598e993a5a0144d9030f13ce
ToppCell	3'-Child04-06-SmallIntestine-Endothelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.14e-05	198	126	6	bf4e086c3fc924e999b6eaca87d2beee9b9526c2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 STARD9	2.14e-05	198	126	6	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 VWF PCDH17 TGFBR2 THBD MAP4K2	2.14e-05	198	126	6	f7a957e8f09d54a55a5dbecfaa9cdf01e6fd543d
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.20e-05	199	126	6	07bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.20e-05	199	126	6	8b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.20e-05	199	126	6	da5a88749d859d535daa030d0974485906cc0ba7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.20e-05	199	126	6	f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.20e-05	199	126	6	68412bc39639edc4045437d62548f7101b9f1989
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 VWF PCDH17 TGFBR2 THBD MAP4K2	2.20e-05	199	126	6	735e165580136576d39e18060550b57b8c808694
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	RNF130 FAM178B STAT5A GMPS GAR1 UNG	2.20e-05	199	126	6	6f159c1215439ec22374903124085746fa8da333
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SELP HSPG2 FLNB VWF PCDH17 THBD	2.20e-05	199	126	6	15db14eff63d5edeced0738542d5fb739225511b
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	e6d36be0c4c569e27303bb4e4f34cd2187e9759d
ToppCell	cellseq2-Endothelial\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	81bdf7a1ddc3e82b96526449e662cca26d7297b1
ToppCell	Parenchyma_COVID-19-Endothelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	abcbd5a156aa4fd51d284441388975c81c0b88ae
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELP HSPG2 VWF APLP1 PCDH17 THBD	2.26e-05	200	126	6	7547d6339f9380d031cfd2cce21ac9a12491e085
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	147ceed692655f4ed73b8a57b0b3224def1f3055
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Macrophages\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	c0c51719cf81512c50bfcc2fed883c867e522d2a
ToppCell	Lung_Parenchyma-Severe-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	d9d0ffa18e5b4647966e19ad9830cbba6120677e
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	758840c31f2ddd7ccf7bf13252ebb48d33e89479
ToppCell	proximal-Endothelial-Bronchial_Vessel_1\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 VWF ARID5A PCDH17 THBD	2.26e-05	200	126	6	d034bd210c87b704acf45f50d888497c8737011b
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell	cellseq2-Endothelial-Endothelial_Vascular\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	dc244a5ccec1b793dc4371fb2cd2c3fd4226283e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	2e47888e041ec3d265425d1df97b6665c6da889c
ToppCell	distal-Endothelial-Vein-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 FLNB VWF PCDH17 THBD	2.26e-05	200	126	6	ff88d28162e0231d5dac0e0c6bec98fa8da58a23
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	e9d5ba140cabae11c437012d519b85f5412dcc94
ToppCell	normal_Lung-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	SELP HSPG2 FLNB VWF MYCBP2 ITPR2	2.26e-05	200	126	6	413ac64bbe95b8c921c5396d8b5f298fec8c4f82
ToppCell	medial-Endothelial-Vein-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 FLNB VWF PCDH17 THBD	2.26e-05	200	126	6	3f689029f5bc7db0af50a405f1e252aeec529077
ToppCell	distal-2-Endothelial-Vein\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 FLNB VWF PCDH17 THBD	2.26e-05	200	126	6	2785225956d2422acab90e99b7debe3709cf3308
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	50fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCell	medial-Endothelial-Vein\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 FLNB VWF PCDH17 THBD	2.26e-05	200	126	6	1163e5f6dfb304c94bf8885629350454f4b6bee8
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Bronchial_vessel-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELP HSPG2 FLNB VWF PCDH17 TGFBR2	2.26e-05	200	126	6	c55efd997392e99068b673542f56f1a209c5a6c8
ToppCell	proximal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 VWF ARID5A PCDH17 THBD	2.26e-05	200	126	6	0ff4185021ec84b57be13b28495e2f8a4d195eb6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	ced14d83222dbebca85c40540e76824e683354f3
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Bronchial_vessel\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SELP HSPG2 FLNB VWF PCDH17 TGFBR2	2.26e-05	200	126	6	a18817d36b2b30a32e1513d36174bf98dfea2a92
ToppCell	medial-2-Endothelial-Vein\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 FLNB VWF PCDH17 THBD	2.26e-05	200	126	6	49da4e3ff10262a492c2cf566a7f2e35e418bfda
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	SELP HSPG2 FLNB VWF THBD KCNN4	2.26e-05	200	126	6	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	0afc7a0f87eac48f772759c3b626758089733361
ToppCell	proximal-Endothelial-Bronchial_Vessel_1-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP HSPG2 VWF ARID5A PCDH17 THBD	2.26e-05	200	126	6	e4f6e0b9502eb531f28d605f9dbda6a72a9ed320
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Bronchial_vessel\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP HSPG2 FLNB VWF PCDH17 TGFBR2	2.26e-05	200	126	6	71979bbcc035d5b8882f1502b5a8ef248aaba45a
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELP HSPG2 VWF PCDH17 TGFBR2 THBD	2.26e-05	200	126	6	c37fe06a94e5779c56e01389869bb432d3bbaebc
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HSPG2 COL7A1 FAM178B LAMA1 MUSK	3.98e-05	134	126	5	b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 LAMA1 SIGLEC15 L3MBTL1 C4BPB	5.07e-05	141	126	5	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 LAMA1 SIGLEC15 L3MBTL1 C4BPB	5.07e-05	141	126	5	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 LAMA1 SIGLEC15 L3MBTL1 C4BPB	5.24e-05	142	126	5	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	remission-multiplets\|remission / disease stage, cell group and cell class	SELP CNTNAP1 LCN2 SIGLEC15 PDF	6.59e-05	149	126	5	e9974260a5f2999b363f306cae005698c912893a
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A	COL7A1 FRAS1 CUL9 ARID5A ITPR2 L3MBTL1 TAGLN3 DUSP10 LDLRAD4 ARAP1	1.26e-07	198	123	10	3324_UP
Drug	Iopanoic acid [96-83-3]; Up 200; 7uM; HL60; HT_HG-U133A	HSPG2 COL7A1 ARID5A L3MBTL1 CELSR3 MARK4 KCNN4 SLC25A44 LDLRAD4	1.12e-06	194	123	9	2965_UP
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX12P DDX11 DDX11L8	6.23e-08	3	118	3	DOID:0060535 (implicated_via_orthology)
Disease	brain small vessel disease (is_marker_for)	SELP THBD	1.59e-05	2	118	2	DOID:0112313 (is_marker_for)
Disease	neutrophil count	SELP FLNB NEK6 MYCBP2 LCN2 ITPR2 MED24 MST1R LINGO1 LRP10 SH3D19 MARK4 TBC1D14 PKD1 ZNF282 MUSK	1.26e-04	1382	118	16	EFO_0004833
Disease	cortical thickness	MON2 HSPG2 FLNB MYCBP2 FAM178B LAMA1 CUL9 SPNS3 PCDH17 BNC1 PKD1 MAEL MUSK ELL	1.48e-04	1113	118	14	EFO_0004840
Disease	cerebrospinal fluid biomarker measurement, monocyte chemotactic protein 1 measurement	NIBAN1 UNC5D	2.35e-04	6	118	2	EFO_0006794, EFO_0010596
Disease	familial combined hyperlipidemia (is_marker_for)	VWF THBD	2.35e-04	6	118	2	DOID:13809 (is_marker_for)
Disease	juvenile rheumatoid arthritis (is_marker_for)	SELP THBD	4.37e-04	8	118	2	DOID:676 (is_marker_for)
Disease	response to carboplatin, response to antineoplastic agent	FLNB LRIG1	6.99e-04	10	118	2	GO_0097327, GO_0097328
Disease	obesity (is_marker_for)	SELP VWF LCN2 THBD	7.36e-04	101	118	4	DOID:9970 (is_marker_for)
Disease	granulocyte percentage of myeloid white cells	FLNB NEK6 TBC1D14 KCNN4 NEURL4 MUSK	7.48e-04	268	118	6	EFO_0007997
Disease	obsolete aging, epigenetic status	SELP PTPRT P2RX6	8.35e-04	46	118	3	EFO_0000473, GO_0007568
Disease	end stage renal disease (is_marker_for)	VWF LCN2 THBD	8.35e-04	46	118	3	DOID:783 (is_marker_for)
Disease	Thrombus	SELP VWF THBD	8.35e-04	46	118	3	C0087086
Disease	eosinophil count	MON2 PRKD2 NEK6 ARID5A STAT5B MED24 TRABD FAM3A MARK4 NFKBIL1 TBC1D14 ZNF319 ZNF282 LDLRAD4 MUSK	8.85e-04	1488	118	15	EFO_0004842
Disease	Dupuytren Contracture	DCHS2 PJA2 DUSP10 ELL	9.45e-04	108	118	4	EFO_0004229
Disease	Thrombosis	SELP VWF THBD	1.00e-03	49	118	3	C0040053
Disease	Hirschsprung's disease (implicated_via_orthology)	ITGB1 MED24	1.02e-03	12	118	2	DOID:10487 (implicated_via_orthology)
Disease	body mass index, fasting blood glucose measurement	MAP4K2 MUSK ARAP1	1.13e-03	51	118	3	EFO_0004340, EFO_0004465
Disease	health study participation	PCDH17 MST1R CELSR3 LINGO1 MARK4	1.15e-03	195	118	5	EFO_0010130
Disease	drug use measurement, depressive symptom measurement, SSRI use measurement	CSMD2 AKTIP	1.20e-03	13	118	2	EFO_0007006, EFO_0007010, EFO_0007011
Disease	pulse pressure measurement	FLNB NEK6 PLXNB2 ARID5A STAT5B GTF2B CYFIP1 LRIG1 PKD1 KCNN4 ROBO3 MAP4K2 MUSK ELL	1.35e-03	1392	118	14	EFO_0005763
Disease	inositol measurement	TAGLN3 ELL	1.40e-03	14	118	2	EFO_0010504
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	PLEKHB1 LINGO1	1.40e-03	14	118	2	EFO_0006830, EFO_0006896
Disease	hair color	FRAS1 NEK6 PLXNB2 DDX11 FZD7 BNC1	1.60e-03	311	118	6	EFO_0003924
Disease	tumor necrosis factor measurement	NFKBIL1 HPX	1.61e-03	15	118	2	EFO_0010834
Disease	platelet measurement	VWF MARK4 TBC1D14 TMEM131L MUSK FBXO34	1.71e-03	315	118	6	EFO_0005036
Disease	thrombomodulin measurement	LAMA1 THBD	2.07e-03	17	118	2	EFO_0007774
Disease	lymphocyte count	FLNB FRAS1 NWD1 PLXNB2 PTPRT STAT5B ITPR2 BNC1 MST1R GTF2B MARK4 TBC1D14 KCNN4 NEURL4	2.16e-03	1464	118	14	EFO_0004587
Disease	lysophosphatidylcholine 22:6 measurement	FZD7 MUSK	2.33e-03	18	118	2	EFO_0010365
Disease	monocyte count	SELP FLNB NEK6 MED24 L3MBTL1 MARK4 NFKBIL1 TBC1D14 PKD1 KCNN4 TMEM131L SLC25A44 ELL	2.42e-03	1320	118	13	EFO_0005091
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNB	2.59e-03	19	118	2	DOID:2256 (is_implicated_in)
Disease	carotid artery disease (is_marker_for)	HSPG2 VWF	2.59e-03	19	118	2	DOID:3407 (is_marker_for)
Disease	age at onset, smoking initiation	MYCBP2 ITPR2	2.59e-03	19	118	2	EFO_0004847, EFO_0005670
Disease	mean platelet volume	NIBAN1 VWF TRABD MARK4 TBC1D14 KCNN4 TMEM131L C4BPB MUSK FBXO34 ARAP1	2.64e-03	1020	118	11	EFO_0004584
Disease	cortical surface area measurement	MON2 PRKD2 FLNB DCHS2 MYCBP2 ENPP3 FAM178B CUL9 PLXNB2 PLEKHB1 LRIG1 PKD1 MAEL	2.84e-03	1345	118	13	EFO_0010736
Disease	coagulation factor V measurement	SELP MUSK	2.87e-03	20	118	2	EFO_0008087
Disease	hair colour measurement	FRAS1 NEK6 PLXNB2 DDX11 FZD7 BNC1 SLC45A1 ELL	3.36e-03	615	118	8	EFO_0007822
Disease	BMI-adjusted fasting blood glucose measurement	MAP4K2 MUSK	3.80e-03	23	118	2	EFO_0008036
Disease	feeling miserable measurement	MED24 MST1R LINGO1	3.95e-03	79	118	3	EFO_0009598

Protein segments in the cluster

Peptide	Gene	Start	Entry
QAHGLCFSVQRPVPP	UNG	161	P13051
GEDQVHPPLCHFPQR	AHRR	476	A9YTQ3
REEAQAGPCPAAPIF	ARID5A	326	Q03989
VAFRCLDPVPHPINF	CNTNAP1	351	P78357
GHISIPQPDCPAEAR	ELL	61	P55199
FRHNECPDPGVPVNG	CSMD2	686	Q7Z408
QDCPPLPAGVSFHID	FBXO34	371	Q9NWN3
PFPEGERPCHRESVI	BNC1	601	Q01954
DCPRLVFDIPVFHPL	AKTIP	136	Q9H8T0
PLVLCHGEAPDFSRP	APCDD1L	451	Q8NCL9
PHHQVVPFRCLPGEF	APLP1	131	P51693
CAHPVLVPLGGFLQP	NWD1	841	Q149M9
VQARDLGPNPIPAHC	PCDH17	321	O14917
LELVPQRGPCPDGHF	HSPG2	496	P98160
HLGCDPQTRFFVPPN	RNF130	86	Q86XS8
HVVENPECPTGPDII	ITGB1	716	P05556
RCVVHPEAGDLANPP	ITPR2	36	Q14571
PEGPGCRVLFHVLPL	MAP4K2	671	Q12851
GEGTPVEHVRCFQPP	CYFIP1	1231	Q7L576
LGFEIVRPGHPCVPS	OAZ2	156	O95190
PNRIQHVFCDFPPVL	OR6N1	171	Q8NGY5
PNIIDHVVCDPGPLF	OR11H2	186	Q8NH07
PPLSCGHQELAFIPE	FRAS1	131	Q86XX4
IIFPNHACEDPPAVL	LRP10	21	Q7Z4F1
LPPHCEQRFLPCEIG	MAEL	126	Q96JY0
FQEREVPCHRPSPGA	MAVS	501	Q7Z434
ELVVCGLHPAPVRGP	KCNN4	111	O15554
ITEVRNTCFPHGPPI	LRIG1	151	Q96JA1
PDRVFHVCPRLAPLG	MAP7D2	196	Q96T17
EIEPFPSHQACIPIS	DSG4	851	Q86SJ6
HLPSQGPVIIDCRPF	DUSP10	166	Q9Y6W6
AVEEAPVNACPPGFR	FLNB	1711	O75369
HVTGPVEDNARCYPP	PLXNA3	66	P51805
PPHPARVEGEAVICN	PLXNB2	561	O15031
CPQVEGLAGPHLVPV	PLXNB3	681	Q9ULL4
RPLCTGHQEPGVEEP	LENG9	216	Q96B70
FPREPIHVGAPEQVA	L3MBTL1	41	Q9Y468
ARDGPCEFAPVVVVP	IGFBPL1	146	Q8WX77
ICPDPHQRPDIGYVH	NEK6	286	Q9HC98
SLVPPGTNPHCFEIV	PRKD2	456	Q9BZL6
TVQFVCRADGDPPPA	LINGO1	441	Q96FE5
VDAGQPPPLHRACAR	NFKBIL1	61	Q9UBC1
VVLNRPFHPAPPFDC	MON2	1006	Q7Z3U7
EQIHLVPAEPPEACG	PRADC1	61	Q9BSG0
EFSCGHVIPPDNILP	DDX11	646	Q96FC9
EPPFSHVCQVGDPVL	PDF	61	Q9HBH1
HVFQPREPDPSICVV	PNPLA7	171	Q6ZV29
EDPPVHVRCSDPNVI	NPHP4	1166	O75161
FLNPPEAGPIVVHCS	PTPRT	1071	O14522
RPFFPQCLPGKELHV	DCHS2	1291	Q6V1P9
LPENHIVFPVPIDQC	LCN2	181	P80188
LPQPCPEEHLAFRVV	FAM3A	61	P98173
ISVPDHGFCQPISIP	FZD7	41	O75084
EEIGPSICRHNPVFG	ACTR3	401	P61158
IQFLCSPRPEEPIEH	HEATR5B	1596	Q9P2D3
HPFPGPGLAIRVICA	GMPS	436	P49915
GHPCPNIIDCFVSRP	GJA9	191	P57773
FIIPHRPTNVESCPE	ENPP3	806	O14638
PPDPPRLECVAFSHQ	FNDC3A	951	Q9Y2H6
RHCLQPLPEGQAPFL	FRS3	206	O43559
CGHVIPPDNIPLVIC	DDX11L8	651	A8MPP1
PDVFPIISGCRHPKD	IGHD	6	P01880
FSCGHVIPPDNILPL	DDX12P	666	Q92771
EHCPELPPVDNSIFV	C4BPB	21	P20851
LPVPNEARVNCSHPF	SELP	451	P16109
PEPLSHFEVEVCQLP	MARK4	706	Q96L34
LNDCFVKIPREPGHP	FOXD4L1	161	Q9NU39
QAVPVRPDHCPVCVS	CUL9	2061	Q8IWT3
PVCPRGLADVVFLPH	COL7A1	1046	Q02388
LLPPSHRVNAEPGCV	CELSR3	1931	Q9NYQ7
PCPLELVDFGDLHPQ	SLC45A1	101	Q9Y2W3
GVAVPDVPQPCHALV	NEURL4	1266	Q96JN8
EPVFPIACHRLCEGP	MPHOSPH8	746	Q99549
AQVQGRCPEHPSVPL	P2RX6	121	O15547
AVHPLCPSDTEIFPG	PKD1	401	P98161
PNIIDHVVCDPGPRF	OR11H1	186	Q8NG94
PNIIDHVVCDPGPRF	OR11H12	186	B2RN74
RFGQCVPPPVHTLLA	OR52M1	266	Q8NGK5
PPERVVLLGEFLHPC	GAR1	66	Q9NY12
FPGIPSPLDAAVECH	HPX	136	P02790
AEGFAPIPHEPHRCQ	THBD	391	P07204
HAFRALCTAEGEPPP	SIGLEC15	181	Q6ZMC9
CLGVHPVQGLPPEDQ	TATDN3	66	Q17R31
NPHIDEIGLIPCPEA	PTAR1	26	Q7Z6K3
REGIFPAVFVRPCPA	SH3D19	706	Q5HYK7
AAAGHFHVPPVPCRV	TMEM131L	131	A2VDJ0
LQCAEDIEHPPPGRA	TAGLN3	36	Q9UI15
GEPHIVLAQPFAGRC	LGI4	231	Q8N135
VHPGETVFLPRCHPL	FAM178B	261	Q8IXR5
LPEPRAFPEQCVVDA	LAMA1	2691	P25391
EGKILNPDHPCFRPD	MED24	536	O75448
EPPFGSKVREHPCVE	TGFBR2	471	P37173
AEHLCQQLPIPGPVE	STAT5B	296	P51692
QLEGTECPLHVVHPP	MYCBP2	4646	O75592
PKECPHIVFQAVSGP	SLC25A44	216	Q96H78
APCRHPREALDGPVF	STARD9	2916	Q9P2P6
RAELVCLSGPHPVPD	OVCA2	36	Q8WZ82
GHCVPPADPRVQIVL	SUSD6	186	Q92537
AEHLCQQLPIPGPVE	STAT5A	296	P42229
IVCLAVPPPDTHGFE	ARAP1	801	Q96P48
CPFPHVVRAGAIFVP	C15orf39	831	Q6ZRI6
SPCRPQDIDFHVPSE	CNOT2	406	Q9NZN8
LEIGNPEPVPCSAVH	TBC1D14	71	Q9P2M4
PVPQGVCPAHREPLA	TRIM11	86	Q96F44
TSVFARCHPLVDPEP	VWF	231	P04275
REAQPPCPEAHGEEL	NIBAN1	771	Q9BZQ8
LEARVVHGLQPPCFQ	SPNS3	286	Q6ZMD2
CVRPPAPNLAGAVEF	REV1	1151	Q9UBZ9
PRVTCPNHPDAILVE	GTF2B	11	Q00403
KIGPECHDVQPPEGR	PLEKHB1	76	Q9UF11
VPFCKFHLGDRPIPV	TRABD	181	Q9H4I3
PGPVRHCQIPDLPVD	TMEM39A	56	Q9NV64
HGIDITCPQEPLSFP	SPATA31D1	1421	Q6ZQQ2
EPAVLECVPPRGHPE	ROBO3	181	Q96MS0
PGEAPPELLCLVSHF	TAPBP	306	O15533
IVLHCRPPEGVPAAE	UNC5D	176	Q6UXZ4
VDEPPGICPHFAQDI	ZNF726	71	A6NNF4
ELLQHPCTPSGERPF	ZNF319	301	Q9P2F9
EPVPNCADVRGTFPA	STRCP1	1456	A6NGW2
EAFACPRVPLPVAGH	TRIM50	396	Q86XT4
CPVCRRHFPPAVIEA	PJA2	671	O43164
QHEFRGDMVVCPLPP	MST1R	906	Q04912
LPPEEVCHQEPALRG	ZNF282	31	Q9UDV7
QCHVEEAAAGRPPPQ	ZNF628	406	Q5EBL2
NCLLVTEHPPPGIFN	LDLRAD4	46	O15165
NHIFQECSPGVVPTP	MUSK	376	O15146