Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNAD+-protein-cysteine ADP-ribosyltransferase activity

PARP6 PARP8

7.08e-056442GO:0140803
DomainBBOX

TRIM43B TRIM43 TRIM49B

5.73e-0469443SM00336
DomainButyrophylin

TRIM43B TRIM43 TRIM49B

5.98e-0470443IPR003879
Domain-

TRIM43B TRIM43 TRIM49B

6.23e-04714434.10.45.10
DomainPoly(ADP-ribose)pol_cat_dom

PARP6 PARP8

7.21e-0417442IPR012317
DomainPARP_CATALYTIC

PARP6 PARP8

7.21e-0417442PS51059
DomainPARP

PARP6 PARP8

7.21e-0417442PF00644
Domain-

PARP6 PARP8

7.21e-04174423.90.228.10
DomainZF_ZZ_2

DMD NBR1

8.10e-0418442PS50135
DomainZF_ZZ_1

DMD NBR1

8.10e-0418442PS01357
DomainZZ

DMD NBR1

8.10e-0418442PF00569
DomainZF_BBOX

TRIM43B TRIM43 TRIM49B

8.83e-0480443PS50119
DomainZnf_ZZ

DMD NBR1

9.04e-0419442IPR000433
DomainZnF_ZZ

DMD NBR1

9.04e-0419442SM00291
DomainZnf_B-box

TRIM43B TRIM43 TRIM49B

9.16e-0481443IPR000315
Domain-

EFL1 TOP2A

1.11e-03214423.30.230.10
DomainSPRY

TRIM43B TRIM43 TRIM49B

1.13e-0387443SM00449
DomainRibosomal_S5_D2-typ_fold_subgr

EFL1 TOP2A

1.22e-0322442IPR014721
DomainHomeobox_metazoa

HOXD1 NKX2-4 HOXA1

1.24e-0390443IPR020479
DomainActinin_actin-bd_CS

DST DMD

1.33e-0323442IPR001589
DomainACTININ_2

DST DMD

1.33e-0323442PS00020
DomainACTININ_1

DST DMD

1.33e-0323442PS00019
DomainSpectrin

DST DMD

1.33e-0323442PF00435
DomainSPRY

TRIM43B TRIM43 TRIM49B

1.41e-0394443PF00622
DomainSPRY_dom

TRIM43B TRIM43 TRIM49B

1.41e-0394443IPR003877
DomainWGR_domain

PARP6 PARP8

1.45e-0324442IPR008893
DomainANTENNAPEDIA

HOXD1 HOXA1

1.45e-0324442PS00032
DomainB30.2/SPRY

TRIM43B TRIM43 TRIM49B

1.45e-0395443IPR001870
DomainB302_SPRY

TRIM43B TRIM43 TRIM49B

1.45e-0395443PS50188
DomainSpectrin_repeat

DST DMD

2.11e-0329442IPR002017
DomainHomeobox

NANOGNB HOXD1 NKX2-4 HOXA1

2.20e-03234444PF00046
DomainHOMEOBOX_1

NANOGNB HOXD1 NKX2-4 HOXA1

2.27e-03236444PS00027
DomainHOX

NANOGNB HOXD1 NKX2-4 HOXA1

2.30e-03237444SM00389
DomainHomeobox_dom

NANOGNB HOXD1 NKX2-4 HOXA1

2.38e-03239444IPR001356
DomainHOMEOBOX_2

NANOGNB HOXD1 NKX2-4 HOXA1

2.38e-03239444PS50071
DomainSpectrin/alpha-actinin

DST DMD

2.57e-0332442IPR018159
DomainSPEC

DST DMD

2.57e-0332442SM00150
DomainRibosomal_S5_D2-typ_fold

EFL1 TOP2A

2.90e-0334442IPR020568
Domain-

PAN3 ZC3H6

4.00e-03404424.10.1000.10
Domain-

NANOGNB HOXD1 NKX2-4 HOXA1

4.35e-032834441.10.10.60
DomainWW

MAGI1 DMD

5.48e-0347442PF00397
DomainZnF_C3H1

PAN3 ZC3H6

5.71e-0348442SM00356
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM43B TRIM43 TRIM49B

9.11e-071545319703589
Pubmed

Phospholipase D1 facilitates second-phase myoblast fusion and skeletal muscle regeneration.

PLD1 DMD

1.64e-06245225428992
Pubmed

BPAG1n4 is essential for retrograde axonal transport in sensory neurons.

DST DCTN1

1.64e-06245214581450
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST DMD

9.81e-0644528954775
Pubmed

Roles of Hox genes: what we have learnt from gain of function and loss of function mutations in the mouse.

HOXD1 HOXA1

9.81e-0644527915637
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

TRIM43B TRIM43 BRD3 DST DMD DCTN1 TOP2A PALB2 PARP8 GRK6

1.23e-051442451035575683
Pubmed

Ectopic Hoxa-1 induces rhombomere transformation in mouse hindbrain.

HOXD1 HOXA1

3.42e-0574527956823
Pubmed

The PARP superfamily.

PARP6 PARP8

4.56e-05845215273990
Pubmed

Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock.

HOXD1 HOXA1

4.56e-05845211511348
Pubmed

The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution.

HOXD1 HOXA1

4.56e-0584521688181
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

TRIM43B TRIM43 TRIM49B

5.07e-055545319468303
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

MAGI1 NBR1 TOP2A HS2ST1

5.42e-0515945430581152
Pubmed

A PAK5-DNPEP-USP4 axis dictates breast cancer growth and metastasis.

DMD TOP2A

5.86e-05945231219614
Pubmed

Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos.

HOXD1 HOXA1

5.86e-0594528102800
Pubmed

Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport.

DST DCTN1

5.86e-05945217287360
Pubmed

Hox-1.11 and Hox-4.9 homeobox genes.

HOXD1 HOXA1

1.47e-04144521348361
Pubmed

A distinct Hox code for the branchial region of the vertebrate head.

HOXD1 HOXA1

1.70e-04154521682814
Pubmed

Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.

DMD LXN

1.70e-041545211353388
Pubmed

p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.

NBR1 PALB2

1.70e-041545230126895
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

PARP6 PARP8

1.94e-041645225043379
Pubmed

An NAD+-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39.

LYAR TOP2A

2.20e-041745232711345
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

PDE3A DST DMD TOP2A

2.40e-0423445436243803
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TRIM43B GPAM BRD3 DST RANBP3L ICA1

3.55e-0473645629676528
Pubmed

A human MAP kinase interactome.

MAGI1 TBX3 DST DMD DCTN1

4.02e-0448645520936779
Pubmed

POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia.

TBX3 LXN

4.07e-042345217239249
Pubmed

Cdx is crucial for the timing mechanism driving colinear Hox activation and defines a trunk segment in the Hox cluster topology.

HOXD1 HOXA1

4.07e-042345228041967
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

DST NBR1 ITPKA

4.07e-0411145322558309
Pubmed

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

PDE3A PIK3CB

5.63e-042745211156964
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

MAGI1 FHIP1A TOP2A

5.76e-0412545329467281
Pubmed

Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps.

TBX3 HOXD1

6.06e-042845217698011
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

DST PAN3 GRK6

8.34e-0414245311812828
Pubmed

Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.

LXN HOXD1

9.48e-043545218498732
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

DST DMD DCTN1

9.96e-0415145317043677
Pubmed

Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons.

LXN HOXD1

1.06e-033745218498735
Pubmed

Atlas of Hox gene expression in the developing kidney.

HOXD1 HOXA1

1.12e-033845215042701
Pubmed

Complete mutation analysis panel of the 39 human HOX genes.

HOXD1 HOXA1

1.12e-033845211857506
Pubmed

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.

HOXD1 HOXA1

1.18e-033945233257809
Pubmed

Quantification of Hox and surfactant protein-B transcription during murine lung development.

HOXD1 HOXA1

1.24e-034045219204410
Cytoband2q11.1

TRIM43B TRIM43

3.49e-04284522q11.1
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP6 PARP8

2.88e-0417272684
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DMD NBR1

3.24e-041827291
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM43B TRIM43 TRIM49B

3.75e-049527359
GeneFamilyHOXL subclass homeoboxes

HOXD1 HOXA1

2.72e-0352272518
GeneFamilyRing finger proteins

TRIM43B TRIM43 TRIM49B

7.77e-0327527358
CoexpressionWATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP

FHIP1A HS2ST1 ICA1

4.20e-0619443M12084
CoexpressionGSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP

ASCC1 OXR1 EBPL NBR1 PALB2

2.05e-05199445M5809
CoexpressionWANG_LMO4_TARGETS_DN

PDE3A DMD LXN ZNF341 PIK3CB NBR1

2.97e-05361446M12674
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MAGI1 PDE3A TECRL DST DMD

1.03e-06184445ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

MAGI1 PDE3A TECRL DST DMD

1.21e-06190445fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

MAGI1 PDE3A TECRL DST DMD

1.24e-0619144525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

MAGI1 PDE3A TECRL DST DMD

1.38e-0619544575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma|TCGA-Testes / Sample_Type by Project: Shred V9

TRIM43B NANOGNB LYAR TRIM49B

1.08e-051394446b58d01ce9d9ac23434333f9faf1bb0eef14ba90
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MAGI1 PDE3A TECRL DMD

3.30e-051854446baccb26f999145e51b91d94315bf8d4655bef31
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

MAGI1 PDE3A TECRL DMD

3.59e-051894445e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MAGI1 PDE3A DMD FHIP1A

3.59e-051894440a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

MAGI1 PDE3A DMD FHIP1A

3.67e-0519044493c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

MAGI1 PDE3A TECRL DMD

3.67e-05190444de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD FHIP1A

3.90e-05193444dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD FHIP1A

4.06e-05195444f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 DMD PAN3 FHIP1A

4.14e-05196444ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

DST OXR1 RANBP3L FHIP1A

4.14e-0519644404f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI1 DMD PAN3 FHIP1A

4.30e-051984441996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TBX3 PDE3A DMD RANBP3L

4.39e-05199444706b7de777ff86eb22e538ccd5c2987ceb6be308
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TBX3 PDE3A DMD RANBP3L

4.39e-05199444471738f2059e20407572d9c4cbd11812068333ea
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBX3 PDE3A DMD RANBP3L

4.39e-05199444690a4f84b205532c4c9e5c19d5ae430d0655f421
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GPAM FHIP1A TOP2A

1.95e-04114443fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GPAM FHIP1A TOP2A

1.95e-041144432cc5d2da5573650c5232a01e2d2128082c4bffcb
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBX3 PDE3A PLD1

2.38e-04122443c16110934172f174f4aefe14b81abce8514b30f0
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell-Peri|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBX3 PDE3A PLD1

2.38e-04122443006ac4f6807e688554d36557d29d5e5a0bc3c36f
ToppCellfrontal_cortex-Non-neuronal-pericyte_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TBX3 PDE3A PLD1

2.38e-04122443f3d9a5893fdee3562880fb6fc132b88169a7d997
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_only / Treatment groups by lineage, cell group, cell type

LYAR PIK3CB TOP2A

3.41e-041384436ddd50e44a3914596b4cd61ae64a987119fe7979
ToppCellICU-SEP-Lymphocyte-T_NK-Treg|ICU-SEP / Disease, Lineage and Cell Type

FSIP2 MAGI1 ICA1

3.94e-04145443ee99b58462f955b96d036aa67e343db047d66f64
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

PDE3A DMD HOXA1

4.18e-04148443c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

PDE3A DMD HOXA1

4.18e-04148443e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MAGI1 KCNU1 HS2ST1

4.35e-041504436a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic-liver_dendritic_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM43B ZNF341 HS2ST1

4.70e-04154443acfbde0fbc09fd69af62a81f8f63e14e36dd1ae0
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

ERMARD ITPKA HOXA1

4.79e-04155443e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FSIP2 TOP2A ICA1

4.88e-041564431d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FSIP2 TOP2A ICA1

4.88e-041564434877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCellsevere_COVID-19-cDC|severe_COVID-19 / disease group, cell group and cell class (v2)

DST DMD FHIP1A

4.97e-04157443ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A NANOGNB DMD

5.45e-041624435f009b231f21861afee9cc0c569082e1135f929c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A NANOGNB DMD

5.45e-04162443b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 PDE3A PLD1

5.64e-0416444343630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 PDE3A PLD1

5.64e-04164443108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 PDE3A PLD1

5.64e-0416444346208f18325976c89f572f6627aea0582142b92d
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DST DMD PIK3CB

5.85e-04166443b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm_gut_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

LYAR RANBP3L PARP8

5.95e-0416744369de7d7fc69d699eab03dfea84fdb54263aa5a47
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DST DMD PIK3CB

5.95e-04167443e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM161B TOP2A PALB2

5.95e-04167443754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCellDividing_Macrophages-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

RANBP3L TOP2A ITPKA

6.16e-04169443eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD

6.26e-041704433f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

MAGI1 DST FHIP1A

6.26e-04170443e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 PDE3A PLD1

6.26e-0417044399dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX3 PDE3A DMD

6.26e-041704435570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 PDE3A PLD1

6.26e-041704433a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 PDE3A PLD1

6.26e-04170443cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell368C-Lymphocytic-ILC|368C / Donor, Lineage, Cell class and subclass (all cells)

ZNF341 PARP8 GRK6

6.37e-041714433b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell368C-Lymphocytic-ILC-ILC-2|368C / Donor, Lineage, Cell class and subclass (all cells)

ZNF341 PARP8 GRK6

6.37e-04171443fd01076574dcc82bfd4a1538812500543b16794f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

PARP6 PIK3CB HOXA1

6.48e-04172443f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

NANOGNB DST PIK3CB

6.59e-04173443226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

TBX3 PDE3A DMD

6.59e-04173443a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 KCNU1 HOXA1

6.70e-04174443c529f3674b784f872f4387ffdeb46aecb619976b
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

FAM161B LYAR FHIP1A

6.70e-04174443390bd41ef114464f3db3e0cac4e67fe7571b4c23
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP6 LETMD1 LXN

6.70e-04174443c58328c2f262506a4518f49f148e29874faf9171
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBX3 DST DMD

6.81e-041754431799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

LYAR PARP8 ITPKA

6.93e-0417644325c197d3b39deffa4801a1d12cdb54320cbae509
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

GPAM DMD NBR1

6.93e-041764431e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD

6.93e-041764439df7a124ebafb0087da0cda133a394275d7bed81
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 FHIP1A ICA1

6.93e-041764433bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PDE3A LXN RANBP3L

7.16e-04178443c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

MAGI1 DST KCNU1

7.27e-04179443d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 DMD FHIP1A

7.27e-04179443815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell367C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLD1 HS2ST1 PARP8

7.27e-041794435aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCellIIH-CD8-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

GPAM LXN ERMARD

7.39e-04180443d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCellnormal-na-Lymphocytic_NK-T_mait-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

LYAR PARP8 ITPKA

7.39e-04180443e66a8a61b3576ac37de7c559d16d4ed4f7a2fc78
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TBX3 PDE3A DMD

7.51e-04181443451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD

7.51e-04181443719eb532453ab7cd7893726885bc75d74a10b21e
ToppCelldroplet-Kidney-nan-3m-Hematologic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFL1 ZNF341 PALB2

7.51e-0418144358d7e76dfaa818aeaef7f129c4472bf5b6563218
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CB TOP2A ICA1

7.51e-04181443566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

FSIP2 DMD FHIP1A

7.51e-041814435a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CB TOP2A ICA1

7.51e-04181443db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCelldroplet-Kidney-nan-3m-Hematologic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFL1 ZNF341 PALB2

7.51e-041814435d76e99bf2b5b337041efd3cd33bebbb0637b64e
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-MEP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NANOGNB LYAR EBPL

7.51e-04181443ee207ea171e2ffc22a7f850be57bb118a87e0f81
ToppCelldroplet-Kidney-nan-3m-Hematologic-leukocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFL1 ZNF341 PALB2

7.51e-04181443970fc90e27236ee30190f1a02f418a378919c60b
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 DST DMD

7.63e-04182443d6740bca2b974122b8451989365a94a81140afd1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TBX3 PDE3A LXN

7.63e-04182443ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DST OXR1 FHIP1A

7.63e-04182443a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 DST DMD

7.63e-04182443ecb5624c9074cc6449fad961df54c926c2681d54
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSBP DST RANBP3L

7.75e-0418344303c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCellCOVID-19-Heart-CM_4|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD

7.75e-041834432902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCellControl-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

FSIP2 DMD FHIP1A

7.88e-04184443b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 FHIP1A ICA1

7.88e-04184443102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

MAGI1 DST DMD

7.88e-04184443561592edc3083fad41b91811151b442207c65dd9
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD

7.88e-04184443e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellnormal-na-Lymphocytic-lymphocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

TOP2A PALB2 ICA1

7.88e-041844432c286712428662bc4589dc5ac4011bf7ed403cb5
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE3A TECRL DMD

8.00e-04185443549eeb521c3985bff396ea0f202db21822efa51f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

MAGI1 DST DMD

8.00e-0418544332b4e68e551d435a732f253f6ad83408c759a642
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TBX3 PDE3A DMD

8.13e-04186443acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

TBX3 PDE3A DMD

8.13e-0418644367b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 DMD FHIP1A

8.13e-041864432ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSBP BRD3 ICA1

8.13e-0418644360830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSBP BRD3 ICA1

8.13e-0418644337860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSBP BRD3 ICA1

8.13e-04186443baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PDE3A DMD NKX2-4

8.13e-04186443c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBX3 PDE3A DMD

8.13e-04186443888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 DST FHIP1A

8.25e-04187443d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DST OXR1 FHIP1A

8.25e-0418744387b3d0478693d4c54ff06b74e5903036b9c1ee6a
DiseaseNeoplasm of uncertain or unknown behavior of breast

TBX3 PIK3CB PALB2

3.17e-0541443C0496956
DiseaseBreast adenocarcinoma

TBX3 PIK3CB PALB2

3.17e-0541443C0858252
Diseasecancer (implicated_via_orthology)

TBX3 DST PIK3CB TOP2A

6.79e-04268444DOID:162 (implicated_via_orthology)
Diseaseanterior thigh muscle fat infiltration measurement

PDE3A EBPL

8.01e-0428442EFO_0020936
DiseaseAbnormality of radial ray

TBX3 PALB2

1.11e-0333442C4228778
Diseaseposterior thigh muscle fat infiltration measurement

PDE3A EBPL

1.25e-0335442EFO_0020934
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

DMD KCNU1

1.33e-0336442DOID:11723 (implicated_via_orthology)
Diseasecolorectal cancer (is_marker_for)

TBX3 OSBP PIK3CB

1.67e-03157443DOID:9256 (is_marker_for)
DiseaseGastric Adenocarcinoma

BRD3 GRK6

2.07e-0345442C0278701
DiseaseMedulloblastoma

BRD3 PALB2

2.54e-0350442C0025149
DiseaseAcute Cerebrovascular Accidents

TBX3 PDE3A

2.96e-0354442C0751956

Protein segments in the cluster

PeptideGeneStartEntry
YMQNVVVKTLWKHQF

BRD3

41

Q15059
HKIQLEQVQEWKSKM

DCTN1

251

Q14203
MIHQKTQEKIWEFKG

EFL1

791

Q7Z2Z2
VKEWNSVKLHATVMN

ASCC1

296

Q8N9N2
RKIQNHIQTLKKWMA

DMD

1051

P11532
KIMQTFVTQQWKQSK

PARP8

246

Q8N3A8
TQVKIWFQNHRYKMK

NKX2-4

231

Q9H2Z4
MSKVIQKKNHWTSRV

MAGI1

1

Q96QZ7
IKTNMWKHNIKFHQL

LETMD1

106

Q6P1Q0
TQVKIWFQNRRMKQK

HOXD1

271

Q9GZZ0
VQKKTFTKWINQHLM

DST

36

Q03001
FTKWINQHLMKVRKH

DST

41

Q03001
IINKVMSAISKHKIW

FSIP2

4181

Q5CZC0
TQHLLQNHKMWKKVI

PDE3A

1076

Q14432
QSWLELKKMHQKETS

EBPL

186

Q9BY08
QWLEIHKKKSQAMSK

FAM161B

481

Q96MY7
QTWKKHFLNSMKNKI

KCNU1

511

A8MYU2
TQVKIWFQNRRMKQK

HOXA1

271

P49639
MLAQTHSKKWQKSLQ

OSBP

281

P22059
VGQKNHWQKIRTMVN

ITPKA

161

P23677
VIWNLKTGQLLKKMH

PALB2

1036

Q86YC2
LVDMWKKIQHSNIVT

PAN3

536

Q58A45
LWKTHTMQQTKQQRE

OXR1

506

Q8N573
MIVFKNHWAQVVKIL

FHIP1A

26

Q05DH4
KAKFQNWMKNSLKVH

LYAR

111

Q9NX58
MSYQKHQQKWQLPAK

LCE7A

1

P0DV60
WTFSEKKQMLIHLAK

ERMARD

656

Q5T6L9
KSKKWRQMLQFPHIS

GRK6

26

P43250
KKILGMFTSQQWKHL

PARP6

131

Q2NL67
SVVNKMQQKYWETKQ

ICA1

21

Q05084
TWYKMVKIQTVKQVQ

LXN

156

Q9BS40
QLQRSWVKMDQKSKH

TRIM43

211

Q96BQ3
QWMSKVVTFHKLKLT

TBX3

196

O15119
KFIKHWRMKNTGNVK

NBR1

391

Q14596
HFIQRWNFTKIMKSK

PLD1

696

Q13393
FWNIQIHKGQLEMVK

GPAM

201

Q9HCL2
QVRFVKNITSWKEMK

HS2ST1

121

Q7LGA3
MTHKQISQWFCKTRK

NANOGNB

141

Q7Z5D8
TISYIKQMLWKQVHN

PIK3CB

51

P42338
QKSNVKKHMQTHKVW

ZNF341

361

Q9BYN7
KWKVMTQEFINQHTV

ZC3H6

256

P61129
KLWAQMKIQRANHKN

RANBP3L

356

Q86VV4
VKAHQVKNHMWIFVN

TOP2A

351

P11388
QLQRSWVKMDQKSKH

TRIM43B

211

A6NCK2
IQMSLWAQKKHKIYL

TECRL

331

Q5HYJ1
HQEKLLQKMQSLWEK

TRIM49B

136

A6NDI0