Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction(R)-limonene 6-monooxygenase activity

CYP2C19 CYP2C9

2.53e-0521012GO:0052741
GeneOntologyMolecularFunctionlimonene monooxygenase activity

CYP2C19 CYP2C9

2.53e-0521012GO:0019113
GeneOntologyMolecularFunction(S)-limonene 6-monooxygenase activity

CYP2C19 CYP2C9

2.53e-0521012GO:0018675
GeneOntologyMolecularFunction(S)-limonene 7-monooxygenase activity

CYP2C19 CYP2C9

2.53e-0521012GO:0018676
GeneOntologyMolecularFunctionlinoleic acid epoxygenase activity

CYP2C19 CYP2C9

1.51e-0441012GO:0071614
GeneOntologyMolecularFunctionarachidonate 11,12-epoxygenase activity

CYP2C19 CYP2C9

1.51e-0441012GO:0008405
GeneOntologyMolecularFunctionfatty acid omega-1 hydroxylase activity

CYP2C19 CYP2C9

2.51e-0451012GO:0120502
GeneOntologyMolecularFunctionlong-chain fatty acid omega-1 hydroxylase activity

CYP2C19 CYP2C9

2.51e-0451012GO:0120319
GeneOntologyMolecularFunctionarachidonate 14,15-epoxygenase activity

CYP2C19 CYP2C9

2.51e-0451012GO:0008404
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor

CYP2C19 CYP2C9

6.95e-0481012GO:0033695
GeneOntologyMolecularFunctioncaffeine oxidase activity

CYP2C19 CYP2C9

6.95e-0481012GO:0034875
GeneOntologyMolecularFunctionSNAP receptor activity

STX8 USE1 SNAP23

1.01e-03391013GO:0005484
GeneOntologyMolecularFunctionestrogen 16-alpha-hydroxylase activity

CYP2C19 CYP2C9

1.35e-03111012GO:0101020
GeneOntologyBiologicalProcessmicrotubule-based process

ROCK2 KIFBP RIPOR2 SMC1A FYCO1 SRGAP2 DZIP1 CFAP298 AK7 DNAH1 NCOR1 SRGAP2C ZPR1 CEP250 RP1L1 PDE4DIP DIAPH1 CCDC68 CROCC DNAH5 ARHGAP21

1.96e-0810589821GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

ROCK2 KIFBP RIPOR2 SMC1A SRGAP2 DZIP1 AK7 DNAH1 NCOR1 SRGAP2C ZPR1 CEP250 RP1L1 PDE4DIP CCDC68 CROCC DNAH5

4.58e-087209817GO:0000226
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

RIPOR2 SRGAP2 DZIP1 ARHGAP35 CFAP298 AK7 DNAH1 SRGAP2C CEP89 CEP250 RP1L1 ATXN10 CROCC DNAH5

3.34e-066709814GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

RIPOR2 SRGAP2 DZIP1 ARHGAP35 CFAP298 AK7 DNAH1 SRGAP2C CEP89 CEP250 RP1L1 ATXN10 CROCC DNAH5

4.31e-066859814GO:0030031
GeneOntologyBiologicalProcesscilium assembly

DZIP1 ARHGAP35 CFAP298 AK7 DNAH1 CEP89 CEP250 RP1L1 ATXN10 CROCC DNAH5

8.47e-064449811GO:0060271
GeneOntologyBiologicalProcesscilium organization

DZIP1 ARHGAP35 CFAP298 AK7 DNAH1 CEP89 CEP250 RP1L1 ATXN10 CROCC DNAH5

1.62e-054769811GO:0044782
GeneOntologyBiologicalProcessextension of a leading process involved in cell motility in cerebral cortex radial glia guided migration

SRGAP2 SRGAP2C

2.23e-052982GO:0021816
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

ROCK2 RIPOR2 SWAP70 RASGRF2 RASA3 SRGAP2 ARHGAP35 RIN2 ARHGAP21 NOTCH2 GRAP

4.96e-055389811GO:0007264
GeneOntologyBiologicalProcessorganelle assembly

RIPOR2 SMC1A DZIP1 ARHGAP35 CFAP298 AK7 DNAH1 PIKFYVE LMOD3 NCOR1 CEP89 CEP250 RP1L1 ATXN10 CROCC DNAH5

8.74e-0511389816GO:0070925
GeneOntologyBiologicalProcesslinoleic acid metabolic process

CYP2C19 CYP2C9 ALOX12

1.72e-0423983GO:0043651
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

RIPOR2 SWAP70 RASGRF2 RASA3 SRGAP2 ARHGAP35 ARHGAP21 NOTCH2

1.89e-04333988GO:0051056
GeneOntologyBiologicalProcessmodulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration

SRGAP2 SRGAP2C

2.21e-045982GO:0021815
GeneOntologyCellularComponentcilium

ERC1 DZIP1 ARHGAP35 CFAP298 AK7 DNAH1 PIK3R4 CEP89 CEP250 RP1L1 CCDC68 ATXN10 CROCC DNAH5 ANKS3 NOTCH2

4.69e-068989916GO:0005929
GeneOntologyCellularComponentphagocytic vesicle

STX8 SNAP23 SRGAP2 PIK3R4 PIKFYVE ATP6V0A4

1.03e-04157996GO:0045335
GeneOntologyCellularComponentcentriole

DZIP1 CEP89 CEP250 CCDC68 ATXN10 CROCC

1.69e-04172996GO:0005814
GeneOntologyCellularComponentmeiotic cohesin complex

SMC1A RAD21L1

4.59e-047992GO:0030893
GeneOntologyCellularComponentphagocytic vesicle membrane

SNAP23 PIK3R4 PIKFYVE ATP6V0A4

6.53e-0483994GO:0030670
GeneOntologyCellularComponentciliary transition fiber

DZIP1 CEP89

9.75e-0410992GO:0097539
GeneOntologyCellularComponentcohesin complex

SMC1A RAD21L1

1.19e-0311992GO:0008278
GeneOntologyCellularComponentmicrotubule organizing center

ROCK2 ERC1 DZIP1 ARHGAP35 CEP89 CEP250 PDE4DIP DIAPH1 CCDC68 ATXN10 CROCC TAF1D

1.33e-039199912GO:0005815
DomainsrGAP2

SRGAP2 SRGAP2C SRGAP2B

1.49e-0731003IPR030252
DomainFCH

SRGAP2 SRGAP2C SRGAP2B

2.13e-04221003PF00611
DomainFCH

SRGAP2 SRGAP2C SRGAP2B

2.13e-04221003SM00055
DomainFCH_dom

SRGAP2 SRGAP2C SRGAP2B

2.44e-04231003IPR001060
DomainF_BAR

SRGAP2 SRGAP2C SRGAP2B

3.14e-04251003IPR031160
DomainF_BAR

SRGAP2 SRGAP2C SRGAP2B

3.14e-04251003PS51741
DomainPH

ROCK2 SWAP70 RASGRF2 RASA3 NIBAN2 PHLPP1 ARHGAP21

7.39e-042781007SM00233
DomainPH_DOMAIN

ROCK2 SWAP70 RASGRF2 RASA3 NIBAN2 PHLPP1 ARHGAP21

7.55e-042791007PS50003
DomainPH_domain

ROCK2 SWAP70 RASGRF2 RASA3 NIBAN2 PHLPP1 ARHGAP21

7.71e-042801007IPR001849
DomainGAF

EFCAB5 PDE5A

7.78e-0481002IPR003018
DomainGAF

EFCAB5 PDE5A

7.78e-0481002SM00065
DomainHR1

ROCK2 RHPN2

7.78e-0481002PF02185
DomainGAF_dom-like

EFCAB5 PDE5A

9.97e-0491002IPR029016
Domain-

EFCAB5 PDE5A

9.97e-04910023.30.450.40
DomainRho_GTPase_activation_prot

RASA3 SRGAP2 ARHGAP35 ARHGAP21

1.28e-03881004IPR008936
DomainPH

ROCK2 SWAP70 RASGRF2 RASA3 PHLPP1 ARHGAP21

1.45e-032291006PF00169
DomainHEAT

HEATR4 HEATR1 PIK3R4

2.16e-03481003PF02985
DomainDynein_heavy_chain_D4_dom

DNAH1 DNAH5

2.48e-03141002IPR024317
DomainDynein_HC_stalk

DNAH1 DNAH5

2.48e-03141002IPR024743
DomainDynein_heavy_dom-2

DNAH1 DNAH5

2.48e-03141002IPR013602
DomainDHC_N2

DNAH1 DNAH5

2.48e-03141002PF08393
DomainMT

DNAH1 DNAH5

2.48e-03141002PF12777
DomainAAA_8

DNAH1 DNAH5

2.48e-03141002PF12780
DomainATPase_dyneun-rel_AAA

DNAH1 DNAH5

2.48e-03141002IPR011704
DomainAAA_5

DNAH1 DNAH5

2.48e-03141002PF07728
DomainDHC_fam

DNAH1 DNAH5

2.85e-03151002IPR026983
DomainDynein_heavy_dom

DNAH1 DNAH5

2.85e-03151002IPR004273
DomainDynein_heavy

DNAH1 DNAH5

2.85e-03151002PF03028
DomainHEAT

HEATR4 HEATR1 PIK3R4

3.71e-03581003IPR000357
DomainRhoGAP

SRGAP2 ARHGAP35 ARHGAP21

4.48e-03621003SM00324
DomainRhoGAP

SRGAP2 ARHGAP35 ARHGAP21

4.69e-03631003PF00620
DomainRHOGAP

SRGAP2 ARHGAP35 ARHGAP21

4.90e-03641003PS50238
DomainRhoGAP_dom

SRGAP2 ARHGAP35 ARHGAP21

4.90e-03641003IPR000198
Domain-

SRGAP2 ARHGAP35 ARHGAP21

4.90e-036410031.10.555.10
Domain-

ROCK2 SWAP70 RASGRF2 RASA3 NIBAN2 PHLPP1 ARHGAP21

5.05e-0339110072.30.29.30
DomainSNARE

STX8 SNAP23

5.58e-03211002PF05739
PathwayREACTOME_RHOB_GTPASE_CYCLE

ROCK2 SNAP23 ARHGAP35 RHPN2 DIAPH1 ARHGAP21

1.99e-0669776MM15596
PathwayREACTOME_RHOB_GTPASE_CYCLE

ROCK2 SNAP23 ARHGAP35 RHPN2 DIAPH1 ARHGAP21

2.16e-0670776M41806
PathwayREACTOME_RHO_GTPASE_CYCLE

ROCK2 VRK2 SWAP70 RASGRF2 SNAP23 SRGAP2 ARHGAP35 RHPN2 DIAPH1 PDE5A ARHGAP21 GOLGA3

4.20e-064397712MM15595
PathwayREACTOME_RHO_GTPASE_CYCLE

ROCK2 VRK2 SWAP70 RASGRF2 SNAP23 SRGAP2 ARHGAP35 RHPN2 DIAPH1 PDE5A ARHGAP21 GOLGA3

5.41e-064507712M27078
PathwayREACTOME_RAC3_GTPASE_CYCLE

VRK2 SWAP70 SNAP23 SRGAP2 ARHGAP35 ARHGAP21

1.14e-0593776MM15609
PathwayREACTOME_RHOA_GTPASE_CYCLE

ROCK2 RASGRF2 SNAP23 ARHGAP35 RHPN2 DIAPH1 ARHGAP21

1.21e-05142777MM15576
PathwayREACTOME_RAC3_GTPASE_CYCLE

VRK2 SWAP70 SNAP23 SRGAP2 ARHGAP35 ARHGAP21

1.21e-0594776M41818
PathwayREACTOME_RHOA_GTPASE_CYCLE

ROCK2 RASGRF2 SNAP23 ARHGAP35 RHPN2 DIAPH1 ARHGAP21

1.66e-05149777M41805
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

ROCK2 VRK2 SWAP70 RASGRF2 SNAP23 SRGAP2 ARHGAP35 PIK3R4 RHPN2 DIAPH1 PDE5A ARHGAP21 GOLGA3

4.48e-056497713MM15690
PathwayREACTOME_RAC1_GTPASE_CYCLE

VRK2 SWAP70 RASGRF2 SNAP23 SRGAP2 ARHGAP35 ARHGAP21

4.66e-05175777MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

VRK2 SWAP70 RASGRF2 SNAP23 SRGAP2 ARHGAP35 ARHGAP21

6.41e-05184777M41809
PathwayREACTOME_RHOF_GTPASE_CYCLE

SNAP23 SRGAP2 DIAPH1 ARHGAP21

7.15e-0541774MM15630
PathwayREACTOME_RHOF_GTPASE_CYCLE

SNAP23 SRGAP2 DIAPH1 ARHGAP21

7.87e-0542774M41821
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

ROCK2 VRK2 SWAP70 RASGRF2 SNAP23 SRGAP2 ARHGAP35 PIK3R4 RHPN2 DIAPH1 PDE5A ARHGAP21 GOLGA3

1.28e-047207713M41838
PathwayREACTOME_RHOD_GTPASE_CYCLE

VRK2 ARHGAP35 DIAPH1 ARHGAP21

1.97e-0453774M41811
PathwayREACTOME_RHOQ_GTPASE_CYCLE

SNAP23 SRGAP2 ARHGAP35 ARHGAP21

2.79e-0458774MM15602
PathwayREACTOME_RHOQ_GTPASE_CYCLE

SNAP23 SRGAP2 ARHGAP35 ARHGAP21

2.98e-0459774M41812
PathwayREACTOME_RHOD_GTPASE_CYCLE

VRK2 ARHGAP35 DIAPH1 ARHGAP21

4.08e-0464774MM15601
PathwayWP_CILIOPATHIES

CFAP298 AK7 PIK3R4 RP1L1 ATXN10 ANKS3

5.01e-04184776M39880
PathwayREACTOME_RHOC_GTPASE_CYCLE

ROCK2 ARHGAP35 DIAPH1 ARHGAP21

5.74e-0470774MM15597
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

CYP2C19 CYP2C9 SMC1A

6.31e-0431773M39476
PathwayREACTOME_RHOC_GTPASE_CYCLE

ROCK2 ARHGAP35 DIAPH1 ARHGAP21

7.09e-0474774M41807
PathwayREACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET

CYP2C19 CYP2C9

8.07e-048772M27135
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP2C19 CYP2C9

1.03e-039772M27143
PathwayKEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT

STX8 USE1 SNAP23

1.15e-0338773M17857
PathwayWP_G13_SIGNALING

ROCK2 RHPN2 DIAPH1

1.15e-0338773M39606
PathwayWP_G13_SIGNALING_PATHWAY

ROCK2 RHPN2 DIAPH1

1.24e-0339773MM15898
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE

PIK3R4 PIKFYVE

1.29e-0310772MM14644
PathwayREACTOME_RAC2_GTPASE_CYCLE

VRK2 SWAP70 ARHGAP35 ARHGAP21

1.30e-0387774MM15600
PathwayREACTOME_RAC2_GTPASE_CYCLE

VRK2 SWAP70 ARHGAP35 ARHGAP21

1.36e-0388774M41810
PathwayREACTOME_CYP2E1_REACTIONS

CYP2C19 CYP2C9

1.57e-0311772M27130
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE

PIK3R4 PIKFYVE

1.57e-0311772M655
PathwayREACTOME_CDC42_GTPASE_CYCLE

RASGRF2 SNAP23 SRGAP2 ARHGAP35 ARHGAP21

1.57e-03155775M41808
PathwayREACTOME_CDC42_GTPASE_CYCLE

RASGRF2 SRGAP2 ARHGAP35 ARHGAP21

1.73e-0394774MM15598
PathwayWP_OCTADECANOID_FORMATION_FROM_LINOLEIC_ACID

CYP2C19 CYP2C9

1.88e-0312772M48064
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STX8 KIFBP VRK2 USE1 MTHFD1L SNAP23 LAMC1 SMPD4 NIBAN2 HEATR1 DZIP1 HM13 DPP9 CEP89 ZNF644 SIK2 ATXN10 GOLGA3 NOTCH2 HERC5

1.28e-0814871032033957083
Pubmed

Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

SRGAP2 SRGAP2C SRGAP2B

2.52e-083103322559944
Pubmed

Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.

SRGAP2 SRGAP2C SRGAP2B

1.01e-074103322559943
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

USP53 NES ERC1 LAMC1 SRGAP2 DZIP1 PIK3R4 CEP89 AASS SIK2 PPIP5K2 ARHGAP21 NOTCH2 TP53BP2

2.62e-078611031436931259
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RASGRF2 SMC1A LAMC1 DZIP1 PPP1R7 NCOR1 PDE4DIP ATXN10 MGA ARHGAP21 NOTCH2

2.78e-074971031123414517
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SECISBP2L MTA2 ROCK2 KIFBP FOXK2 ERC1 SMC1A SRGAP2 HEATR1 HM13 PPP1R7 PDE5A ATXN10 PPIP5K2 ANKS3 TP53BP2 CCDC144A

3.38e-0713211031727173435
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ROCK2 RASA3 SNAP23 SRGAP2 NIBAN2 DZIP1 CEP89 ARHGAP21 GOLGA3 NOTCH2

5.26e-074211031036976175
Pubmed

Network organization of the human autophagy system.

MTA2 STX8 MYH4 ERC1 SMC1A SNAP23 FYCO1 PIK3R4 GOLGA3 TP53BP2

7.38e-074371031020562859
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ROCK2 NES KIFBP ERC1 FYCO1 SRGAP2 PPP1R7 NCOR1 PDE4DIP DIAPH1 MGA ARHGAP21 GOLGA3 TP53BP2

9.93e-079631031428671696
Pubmed

Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity.

VRK2 CYP2C19 CYP2C9

1.40e-068103316462940
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

ROCK2 VRK2 SWAP70 USE1 ERC1 SNAP23 SMPD4 NIBAN2 HM13 CROCC

7.56e-065681031037774976
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

ROCK2 STX8 VRK2 SWAP70 SNAP23 NIBAN2 CROCC NOTCH2

7.98e-06339103837232246
Pubmed

CYP2C9, but not CYP2C19, polymorphisms affect the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects.

CYP2C19 CYP2C9

8.69e-062103216198656
Pubmed

Detection of Grb-2-related adaptor protein gene (GRAP) and peptide molecule in salivary glands of MRL/lpr mice and patients with Sjögren's syndrome.

GRAPL GRAP

8.69e-062103215174222
Pubmed

[Association between genetic polymorphisms of CYP2C19 and CYP2C9 and phenytoin serum concentration].

CYP2C19 CYP2C9

8.69e-062103215569425
Pubmed

Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.

GRAPL GRAP

8.69e-062103219836472
Pubmed

Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.

CYP2C19 CYP2C9

8.69e-062103218511451
Pubmed

TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.

TLR3 MGA

8.69e-062103224131248
Pubmed

Developmental expression of human hepatic CYP2C9 and CYP2C19.

CYP2C19 CYP2C9

8.69e-062103214634042
Pubmed

Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.

GRAPL GRAP

8.69e-062103211971956
Pubmed

An association between the rs1799853 and rs1057910 polymorphisms of CYP2C9, the rs4244285 polymorphism of CYP2C19 and the prevalence rates of drug-resistant epilepsy in children.

CYP2C19 CYP2C9

8.69e-062103232567426
Pubmed

CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract.

CYP2C19 CYP2C9

8.69e-062103210908295
Pubmed

Role of CYP2C9 and CYP2C19 polymorphisms in patients with atherosclerosis.

CYP2C19 CYP2C9

8.69e-062103217868191
Pubmed

Impact of CYP2C19 and CYP2C9 gene polymorphisms on sodium valproate plasma concentration in patients with epilepsy.

CYP2C19 CYP2C9

8.69e-062103232868386
Pubmed

CYP2C9 and CYP2C19 Allele and Haplotype Distributions in Four Mestizo Populations from Western Mexico: An Interethnic Comparative Study.

CYP2C19 CYP2C9

8.69e-062103227617498
Pubmed

Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P-450 isozyme.

CYP2C19 CYP2C9

8.69e-06210321847130
Pubmed

Influence of the CYP2C9 AND CYP2C19 polymorphisms on phenytoin hydroxylation in healthy individuals from south India.

CYP2C19 CYP2C9

8.69e-062103216873909
Pubmed

Cytochromes P450 catalyze oxidation of alpha,beta-unsaturated aldehydes.

CYP2C19 CYP2C9

8.69e-062103217599801
Pubmed

The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development.

SRGAP2C SRGAP2B

8.69e-062103231822692
Pubmed

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.

SRGAP2 SRGAP2C

8.69e-062103227373832
Pubmed

Comparison of the in vitro mutagenicity and metabolism of dimethylnitrosamine and benzo[a]pyrene in tissues from inbred mice treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls.

CYP2C19 CYP2C9

8.69e-0621032106274
Pubmed

Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms.

CYP2C19 CYP2C9

8.69e-062103215385837
Pubmed

[Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms].

CYP2C19 CYP2C9

8.69e-062103225518510
Pubmed

Genetic polymorphism of CYP2C9 and CYP2C19 in a Bolivian population: an investigative and comparative study.

CYP2C19 CYP2C9

8.69e-062103215776277
Pubmed

Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.

CEP250 CROCC

8.69e-062103216339073
Pubmed

Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.

CYP2C19 CYP2C9

8.69e-062103215842554
Pubmed

Effect of cytochrome P450 2C19 and 2C9 amino acid residues 72 and 241 on metabolism of tricyclic antidepressant drugs.

CYP2C19 CYP2C9

8.69e-062103224492587
Pubmed

Grb2-related adaptor protein GRAP is a novel regulator of liver fibrosis.

GRAPL GRAP

8.69e-062103237343720
Pubmed

Rapid identification of the hepatic cytochrome P450 2C19 activity using a novel and noninvasive [13C]pantoprazole breath test.

CYP2C19 CYP2C9

8.69e-062103219136640
Pubmed

Mouse Cyp2c expression and zonation structure in the liver begins in the early neonatal stage.

CYP2C19 CYP2C9

8.69e-062103235748067
Pubmed

Phase I pharmacokinetic and pharmacogenomic study of E7070 administered once every 21 days.

CYP2C19 CYP2C9

8.69e-062103216232205
Pubmed

Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.

CYP2C19 CYP2C9

8.69e-062103232587777
Pubmed

Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Mongolian population in China.

CYP2C19 CYP2C9

8.69e-062103220845310
Pubmed

C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.

CEP250 CROCC

8.69e-062103223070519
Pubmed

Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Iranian population.

CYP2C19 CYP2C9

8.69e-062103217201743
Pubmed

CYP2C9 (*2&*3) and CYP2C19 (*2&*3) polymorphisms among children with nonlesional epilepsy: a single-center study.

CYP2C19 CYP2C9

8.69e-062103232683556
Pubmed

Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients.

CYP2C19 CYP2C9

8.69e-062103215855721
Pubmed

Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid.

CYP2C19 CYP2C9

8.69e-06210329721182
Pubmed

The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide in Chinese subjects.

CYP2C19 CYP2C9

8.69e-062103219847408
Pubmed

CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.

CYP2C19 CYP2C9

8.69e-062103217504998
Pubmed

Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors.

CYP2C19 CYP2C9

8.69e-062103224519941
Pubmed

Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.

CYP2C19 CYP2C9

8.69e-062103214623888
Pubmed

Cytochrome P450 polymorphisms in patients with Behcet's disease.

CYP2C19 CYP2C9

8.69e-062103217269966
Pubmed

Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.

CYP2C19 CYP2C9

8.69e-062103211950794
Pubmed

Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to drug-induced idiosyncratic liver injury (DILI).

CYP2C19 CYP2C9

8.69e-062103217279092
Pubmed

Rapid testing of clopidogrel resistance by genotyping of CYP2C19 and CYP2C9 polymorphisms using denaturing on-chip capillary electrophoresis.

CYP2C19 CYP2C9

8.69e-062103222589111
Pubmed

Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin-Induced Cutaneous Adverse Drug Reactions.

CYP2C19 CYP2C9

8.69e-062103232216088
Pubmed

cDNA cloning and sequence of CYP2C29 encoding P-450 MUT-2, a microsomal aldehyde oxygenase.

CYP2C19 CYP2C9

8.69e-06210328130255
Pubmed

Membrane integration of recombinant human P450 forms.

CYP2C19 CYP2C9

8.69e-062103219534586
Pubmed

CYP2C9 and CYP2C19 genetic polymorphisms: frequencies in the south Indian population.

CYP2C19 CYP2C9

8.69e-062103215660966
Pubmed

Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy.

CYP2C19 CYP2C9

8.69e-062103218154472
Pubmed

Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data.

CYP2C19 CYP2C9

8.69e-062103227353638
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects.

CYP2C19 CYP2C9

8.69e-062103217298483
Pubmed

Analysis of the Potential Association of Drug-Metabolizing Enzymes CYP2C9*3 and CYP2C19*3 Gene Variations With Type 2 Diabetes: A Case-Control Study.

CYP2C19 CYP2C9

8.69e-062103233115391
Pubmed

Contributions of CYP2C9/CYP2C19 genotypes and drug interaction to the phenytoin treatment in the Korean epileptic patients in the clinical setting.

CYP2C19 CYP2C9

8.69e-062103217562299
Pubmed

Prevalence of CYP2C9 and CYP2C19 variants and the impact on clopidogrel efficacy in patients having CYPC19*2 variant.

CYP2C19 CYP2C9

8.69e-062103236960518
Pubmed

Characterization of drug-metabolizing enzymes CYP2C9, CYP2C19 polymorphisms in Tunisian, Kuwaiti and Bahraini populations.

CYP2C19 CYP2C9

8.69e-062103226690534
Pubmed

Inter-phenotypic differences in CYP2C9 and CYP2C19 metabolism: Bayesian meta-regression of human population variability in kinetics and application in chemical risk assessment.

CYP2C19 CYP2C9

8.69e-062103233232775
Pubmed

Covariate-based dose individualization of the cytotoxic drug indisulam to reduce the risk of severe myelosuppression.

CYP2C19 CYP2C9

8.69e-062103219199010
Pubmed

Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.

CYP2C19 CYP2C9

8.69e-062103217304159
Pubmed

Genetic Polymorphisms of CYP2C9/CYP2C19 in Chronic Obstructive Pulmonary Disease.

CYP2C19 CYP2C9

8.69e-062103232757668
Pubmed

A comparative analysis of binding sites between mouse CYP2C38 and CYP2C39 based on homology modeling, molecular dynamics simulation and docking studies.

CYP2C19 CYP2C9

8.69e-062103219358898
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on phenytoin-induced neurological toxicity in Indian epileptic patients.

CYP2C19 CYP2C9

8.69e-062103220390258
Pubmed

Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians.

CYP2C19 CYP2C9

8.69e-062103219761366
Pubmed

Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations.

CYP2C19 CYP2C9

8.69e-062103214616425
Pubmed

Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage.

CYP2C19 CYP2C9

8.69e-062103234438105
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.

CYP2C19 CYP2C9

8.69e-062103212496751
Pubmed

Voriconazole metabolism, toxicity, and the effect of cytochrome P450 2C19 genotype.

CYP2C19 CYP2C9

8.69e-062103224403552
Pubmed

Chromosomal organization of the cytochrome P450-2C gene family in the mouse: a locus associated with constitutive aryl hydrocarbon hydroxylase.

CYP2C19 CYP2C9

8.69e-06210322895926
Pubmed

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics and pharmacodynamics of gliclazide in healthy Chinese Han volunteers.

CYP2C19 CYP2C9

8.69e-062103220831536
Pubmed

SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.

CEP250 SIK2

8.69e-062103220708153
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

USP53 ERC1 MTHFD1L SNAP23 PPP1R7 NCOR1 AASS CEP250 PPIP5K2 MGA ARHGAP21 TP53BP2

8.70e-068531031228718761
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

NES VRK2 SNAP23 SMPD4 SRGAP2 HM13 PIKFYVE DIAPH1 PPIP5K2 CROCC MGA

1.16e-057331031134672954
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

MTA2 NES VRK2 FOXK2 SMPD4 HEATR1 ARHGAP35 ARHGAP21 TP53BP2

1.18e-05472103938943005
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

STX8 VRK2 USE1 SNAP23 FYCO1 PIK3R4 PIKFYVE GOLGA3 NOTCH2

1.97e-05504103934432599
Pubmed

An atlas of genetic influences on human blood metabolites.

MGAM CYP2C19 CYP2C9 HEATR4 ZPR1 ALOX12

2.26e-05190103624816252
Pubmed

Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population.

CYP2C19 CYP2C9

2.60e-053103228687336
Pubmed

CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population.

CYP2C19 CYP2C9

2.60e-053103216220110
Pubmed

Cytochrome p450 genotyping by multiplexed real-time dna sequencing with pyrosequencing technology.

CYP2C19 CYP2C9

2.60e-053103215090156
Pubmed

Polymorphic drug metabolizing CYP-enzymes--a pathogenic factor in oral lichen planus?

CYP2C19 CYP2C9

2.60e-053103219192051
Pubmed

Investigation of allele and genotype frequencies of CYP2C9, CYP2C19 and VKORC1 in Iran.

CYP2C19 CYP2C9

2.60e-053103220885015
Pubmed

Association of genetic polymorphisms with warfarin dose requirements in Chinese patients.

CYP2C19 CYP2C9

2.60e-053103223941071
Pubmed

CYP2C29 produces superoxide in response to shear stress.

CYP2C19 CYP2C9

2.60e-053103222708815
Pubmed

Hepatotoxicity of oral and intravenous voriconazole in relation to cytochrome P450 polymorphisms.

CYP2C19 CYP2C9

2.60e-053103217827141
Pubmed

Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19.

CYP2C19 CYP2C9

2.60e-053103223834474
Pubmed

A 2.4-megabase physical map spanning the CYP2C gene cluster on chromosome 10q24.

CYP2C19 CYP2C9

2.60e-05310328530044
Pubmed

Lack of association between genetic polymorphisms of CYP3A4, CYP2C9 and CYP2C19 and antituberculosis drug-induced liver injury in a community-based Chinese population.

CYP2C19 CYP2C9

2.60e-053103223469989
Pubmed

Global pharmacogenomics: Impact of population diversity on the distribution of polymorphisms in the CYP2C cluster among Brazilians.

CYP2C19 CYP2C9

2.60e-053103221173785
Pubmed

Suppression of hepatic ChREBP⍺-CYP2C50 axis-driven fatty acid oxidation sensitizes mice to diet-induced MASLD/MASH.

CYP2C19 CYP2C9

2.60e-053103238740087
Pubmed

Analysis of CYP2C9*2, CYP2C19*2, and CYP2D6*4 polymorphisms in patients with type 2 diabetes mellitus.

CYP2C19 CYP2C9

2.60e-053103221108610
InteractionRAC3 interactions

ROCK2 STX8 VRK2 SWAP70 RASA3 SNAP23 SMPD4 SRGAP2 NIBAN2 ARHGAP35 CEP89 DIAPH1 ARHGAP21 NOTCH2

3.19e-0661910314int:RAC3
InteractionEPHA2 interactions

ROCK2 RASA3 USE1 AXL SNAP23 SRGAP2 NIBAN2 DZIP1 CEP89 PHLPP1 MAP2K5 ARHGAP21 GOLGA3 NOTCH2

1.74e-0571910314int:EPHA2
InteractionPAX6 interactions

FOXK2 CXorf38 SMC1A FYCO1 CFAP298 NCOR1 ZNF644 DIAPH1 MLLT6 MGA

1.82e-0536610310int:PAX6
InteractionCXADR interactions

VRK2 RASA3 SNAP23 SMPD4 NIBAN2 DZIP1 NCOR1 CEP89 GOLGA3 NOTCH2

1.95e-0536910310int:CXADR
InteractionRHOA interactions

ROCK2 STX8 VRK2 RIPOR2 RASGRF2 USE1 SNAP23 SMPD4 NIBAN2 HEATR1 ARHGAP35 HM13 RHPN2 CEP89 DIAPH1 ARHGAP21 GOLGA3 NOTCH2

3.39e-05119910318int:RHOA
InteractionGJA1 interactions

ROCK2 VRK2 RASA3 SNAP23 SMPD4 NIBAN2 DZIP1 PIK3R4 CEP89 ARHGAP21 GOLGA3 NOTCH2

4.27e-0558310312int:GJA1
InteractionZYX interactions

SECISBP2L FOXK2 RASGRF2 NIBAN2 FBXO10 ZPR1 ARHGAP21 NOTCH2 TP53BP2

4.82e-053291039int:ZYX
InteractionRAB9A interactions

STX8 VRK2 SMC1A SNAP23 SMPD4 FYCO1 NIBAN2 HM13 PIK3R4 PIKFYVE GOLGA3 NOTCH2

5.20e-0559510312int:RAB9A
InteractionRALBP1 interactions

NES SRGAP2 ARHGAP35 CEP250 CROCC ARHGAP21 TP53BP2

7.10e-051981037int:RALBP1
InteractionRND3 interactions

ROCK2 VRK2 SNAP23 NIBAN2 HEATR1 ARHGAP35 ARHGAP21 NOTCH2

8.01e-052731038int:RND3
InteractionYWHAZ interactions

RIPOR2 RASGRF2 ERC1 AXL SMC1A LAMC1 SRGAP2 DZIP1 NCOR1 CEP89 AASS ZNF644 SIK2 PPIP5K2 MAP2K5 ARHGAP21 GOLGA3 TP53BP2

1.16e-04131910318int:YWHAZ
InteractionCDC42 interactions

ROCK2 STX8 KIFBP VRK2 RASGRF2 RASA3 USE1 SNAP23 SMPD4 NIBAN2 HEATR1 ARHGAP35 AASS DIAPH1 SIK2 ARHGAP21 NOTCH2 TRIM60

1.20e-04132310318int:CDC42
InteractionSTX7 interactions

STX8 VRK2 SWAP70 USE1 SNAP23 SMPD4 NIBAN2 HM13 CEP89 ARHGAP21 GOLGA3 NOTCH2

1.37e-0465910312int:STX7
InteractionIL17RA interactions

VRK2 ADAMTS12 NCOR1 ZNF644 SIK2 PPIP5K2

1.45e-041551036int:IL17RA
InteractionCDH1 interactions

ROCK2 SWAP70 ERC1 SNAP23 SRGAP2 NIBAN2 UBE2T DIAPH1 PHLPP1 ARHGAP21 GOLGA3 NOTCH2 TP53BP2

1.46e-0476810313int:CDH1
InteractionRHOD interactions

ROCK2 VRK2 RASA3 SNAP23 SMPD4 NIBAN2 ARHGAP35 CEP89 DIAPH1 ARHGAP21 NOTCH2

1.65e-0457210311int:RHOD
InteractionRHOF interactions

ROCK2 VRK2 RASA3 SNAP23 SRGAP2 NIBAN2 PIKFYVE CEP89 DIAPH1 ATXN10 ARHGAP21 NOTCH2

1.66e-0467310312int:RHOF
InteractionRAB35 interactions

VRK2 SNAP23 SMPD4 NIBAN2 DZIP1 HM13 CEP89 DIAPH1 ARHGAP21 GOLGA3 NOTCH2

1.67e-0457310311int:RAB35
InteractionEMD interactions

NEPRO VRK2 CYP2C9 USE1 AXL SMPD4 FYCO1 HM13 NCOR1 SIK2 MAP2K5 GOLGA3 NOTCH2

1.91e-0478910313int:EMD
InteractionUBR1 interactions

NES USE1 ADAMTS12 RPUSD4 CROCC HERC5

1.91e-041631036int:UBR1
InteractionNDC80 interactions

ROCK2 ERC1 SMC1A CEP89 CEP250 CCDC68 GOLGA3 TP53BP2

2.01e-043121038int:NDC80
InteractionCYP2C9 interactions

VRK2 CYP2C19 CYP2C9 ERC1 SMPD4

2.04e-041051035int:CYP2C9
Cytoband17p11.2

CCDC144CP NCOR1 GRAPL CCDC144A GRAP

3.11e-05159103517p11.2
CytobandEnsembl 112 genes in cytogenetic band chr17p11

CCDC144CP NCOR1 GRAPL CCDC144A GRAP

9.91e-052031035chr17p11
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP2 SRGAP2C SRGAP2B

8.17e-05236731288
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ROCK2 SWAP70 RASGRF2 RASA3 PHLPP1 ARHGAP21

1.14e-04206676682
GeneFamilyAnkyrin repeat domain containing

ANKRD36C ANKRD36B ANKS3 NOTCH2 TP53BP2 GABPB1

2.73e-04242676403
GeneFamilyRho GTPase activating proteins|BCH domain containing

SRGAP2 ARHGAP35 ARHGAP21

8.42e-0450673721
GeneFamilySNAREs|BCL2 homology region 3 (BH3) only

USE1 SNAP23

1.38e-03156721124
GeneFamilyDyneins, axonemal

DNAH1 DNAH5

1.77e-0317672536
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SECISBP2L ROCK2 FOXK2 SWAP70 ERC1 LAMC1 SRGAP2 ARHGAP35 PIK3R4 PIKFYVE RIN2 PHLPP1 PPIP5K2 TP53BP2

6.57e-0685610314M4500
CoexpressionERWIN_COHEN_BLOOD_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_2DY_UP

SRGAP2 IFIT2 SRGAP2C RIN2 SRGAP2B HERC5

7.70e-061191036M41139
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

USP53 SWAP70 FYCO1 AK7 TLR3 DNAH5

2.91e-06171103674be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

RIPOR2 SRGAP2 SRGAP2C RIN2 SRGAP2B NOTCH2

5.83e-0619310363479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

RIPOR2 SRGAP2 SRGAP2C RIN2 SRGAP2B NOTCH2

6.19e-061951036fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRF2 ANKRD36C ADAMTS12 RIN2 NOTCH2 HERC5

7.15e-062001036f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRF2 ANKRD36C ADAMTS12 RIN2 NOTCH2 HERC5

7.15e-06200103670a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

RASGRF2 ANKRD36C ADAMTS12 RIN2 NOTCH2 HERC5

7.15e-0620010361639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellLPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 NES IFIT2 MLIP UBE2T

1.99e-051421035b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AXL SRGAP2C TLR3 SRGAP2B CCDC144A

2.20e-0514510359743d68ba8bfef56fd9a979ab357c0e287eb5ae2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VRK2 CYP2C9 IFIT2 MGA HERC5

2.76e-05152103518194f757d319958f26e5a91f56d89f25711236f
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

FYCO1 ZNF644 CROCC MGA NOTCH2

3.75e-051621035810881210e015c788814e4fe8d7a24c929cf2621
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

5.71e-0517710354d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES SMC1A IFIT2 ZNF800 DIAPH1

5.86e-05178103501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

5.86e-051781035edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

6.68e-051831035fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

6.68e-051831035612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

6.68e-0518310357c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

7.04e-0518510359197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

7.04e-051851035ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

7.04e-051851035b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES SRGAP2 SRGAP2C PDE4DIP SRGAP2B

7.40e-05187103524c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 SWAP70 RASA3 NOTCH2 GRAP

7.59e-0518810351f07e3ab87173426fe0c429f5c084fb3425effd3
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 SWAP70 RASA3 NOTCH2 GRAP

7.59e-05188103585746f95319e494efdc1bbc24331698688d3a900
ToppCellfacs-Heart-LV-3m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 FYCO1 LMOD3 MLIP ZNF644

7.59e-05188103540ce7125fca6f6b6b5cc1637c87d43c29b08f4f1
ToppCellfacs-Heart-LV-3m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 FYCO1 LMOD3 MLIP ZNF644

7.59e-051881035ba7f7ce034c0f42742bf2461f68f8d343ee593a5
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

RIPOR2 SRGAP2 SRGAP2C SRGAP2B NOTCH2

7.98e-051901035aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FOXK2 SWAP70 SRGAP2 PIKFYVE SRGAP2C

7.98e-051901035ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

USP53 AXL SRGAP2 SRGAP2C SRGAP2B

8.38e-051921035984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

USP53 MTHFD1L AXL ANKRD36C TLR3

8.59e-051931035198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 LAMC1 ADAMTS12 AASS PDE5A

8.59e-05193103599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 LAMC1 ADAMTS12 AASS PDE5A

8.59e-051931035b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 LAMC1 ADAMTS12 AASS PDE4DIP

8.80e-051941035e93de9428c986b8943fc169258847c650cfab0e5
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

VRK2 AXL IFIT2 ZNF644 HERC5

8.80e-051941035d1366b169d14011194e61d16b6b0953349febc78
ToppCellIPF-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

USP53 AXL SRGAP2 SRGAP2C SRGAP2B

8.80e-051941035accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCellPBMC-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

RIPOR2 AXL SNAP23 PPIP5K2 HERC5

9.01e-051951035674355ca00314bde90ef7f6ddb83afe2d5323130
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

VRK2 CXorf38 AXL ZNF800 NOTCH2

9.23e-0519610357be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

USP53 AXL RIN2 TLR3 SRGAP2B

9.46e-051971035937b70269cec8a4bdf4aaf8baa908c12bc309dc0
ToppCellMild-Myeloid-Macrophages-FCN1_high|Mild / Condition, Lineage, Cell class and cell subclass

SRGAP2 NIBAN2 IFIT2 SRGAP2C RIN2

9.69e-05198103517aab4dc3b2cd6eb7dda77dd51bdc20490fcfe19
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 LAMC1 ADAMTS12 AASS PDE5A

9.69e-051981035f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MTHFD1L AXL SRGAP2 SRGAP2C SRGAP2B

9.92e-051991035744b63fba33b176ab7dde11646ccb313665505f7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

SECISBP2L RIPOR2 ANKRD36B NCOR1 PDE4DIP

9.92e-051991035f30e9d3d095a1e12d759debe27540aad32861db6
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

ROCK2 USP53 NCOR1 ZNF644 CCDC68

9.92e-051991035c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 LAMC1 ADAMTS12 AASS PDE5A

9.92e-05199103566a79732caf2f04c09b4d9832377aa01ca477677
ToppCellCOVID-mono1|COVID / Condition, Cell_class and T cell subcluster

AXL SRGAP2 SRGAP2C RIN2 SRGAP2B

1.02e-042001035bd002c54305c746c07b7418a2084195e9c852ec5
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

USP53 MTHFD1L SRGAP2 SRGAP2C SRGAP2B

1.02e-042001035a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

USP53 MTHFD1L SRGAP2 SRGAP2C SRGAP2B

1.02e-042001035dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

USP53 MTHFD1L SRGAP2 SRGAP2C SRGAP2B

1.02e-0420010353bba5219453322198e8fdb0921d5f8c403598751
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK---L2|Neuronal / cells hierarchy compared to all cells using T-Statistic

VRK2 RASGRF2 RASA3 MLIP CCDC144A

1.02e-0420010356ebdae4438bc64c6620416f64a7e22fbca2664bf
ToppCellCOVID-mono1-|COVID / Condition, Cell_class and T cell subcluster

AXL SRGAP2 SRGAP2C RIN2 SRGAP2B

1.02e-042001035445a1aab962673dcc926c33ce9bed5ede9c41c57
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK-|Neuronal / cells hierarchy compared to all cells using T-Statistic

VRK2 RASGRF2 RASA3 MLIP CCDC144A

1.02e-042001035081ca331b56f85167acfc73af9d2e91f398f8c4d
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

USP53 MTHFD1L SRGAP2 SRGAP2C SRGAP2B

1.02e-04200103521bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK--|Neuronal / cells hierarchy compared to all cells using T-Statistic

VRK2 RASGRF2 RASA3 MLIP CCDC144A

1.02e-04200103566e2f3e2e9063f17b47621120eb6009405f69e7e
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

USP53 MTHFD1L SRGAP2 SRGAP2C SRGAP2B

1.02e-042001035a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

USP53 MTHFD1L SRGAP2 SRGAP2C SRGAP2B

1.02e-04200103533036d21c1c82109284473a515c4f890b33fdd5c
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-LTK|Neuronal / cells hierarchy compared to all cells using T-Statistic

VRK2 RASGRF2 RASA3 MLIP CCDC144A

1.02e-042001035940892bea41fde567f138a896d151acccef03a6a
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil-Neu_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MGAM CYP2C19 RIPOR2 IFIT2

1.57e-041171034089793a950e8593b4acc1ba6a5e5474682f5fda6
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil-Neu_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAM CYP2C19 RIPOR2 IFIT2

1.57e-0411710343d98d77b4725d684e7496059e8b0ffffbe40301d
DrugOxybenzone [131-57-7]; Down 200; 17.6uM; MCF7; HT_HG-U133A

MTA2 ROCK2 NPY5R ARHGAP35 RIN2 CEP250 MAP2K5 NOTCH2

3.21e-0619710385410_DN
DrugAzathymine, 6 [932-53-6]; Down 200; 31.4uM; PC3; HT_HG-U133A

MTA2 SNAP23 ARHGAP35 IFIT2 AASS MAP2K5 ALOX12 GABPB1

3.33e-0619810383987_DN
Drugtrapoxin

MTA2 NES MGAM KIFBP NCOR1

6.51e-06581035CID000121875
DiseaseX-11308 measurement

CYP2C19 CYP2C9 HEATR4

6.11e-06111003EFO_0800693
DiseaseX-21258 measurement

CYP2C19 CYP2C9

3.40e-0531002EFO_0800802
DiseasePrimary ciliary dyskinesia

CFAP298 DNAH1 DNAH5

2.49e-04361003cv:C0008780
Diseasetyrosine-protein kinase receptor TYRO3 measurement

MGAM MGA

3.14e-0481002EFO_0020829
DiseaseX-17653 measurement

CYP2C19 HEATR4

4.03e-0491002EFO_0800783
DiseasePrimary Ciliary Dyskinesia

CFAP298 DNAH1 DNAH5

5.50e-04471003C4551720
Diseasecytochrome p450 3a4 measurement

PIKFYVE ZPR1

6.13e-04111002EFO_0020303
Diseasethymol sulfate measurement

CYP2C19 CYP2C9

7.34e-04121002EFO_0021170
Diseasepre-eclampsia (implicated_via_orthology)

PDE5A NOTCH2

8.66e-04131002DOID:10591 (implicated_via_orthology)
DiseaseX-17654 measurement

CYP2C9 HEATR4

1.16e-03151002EFO_0800784
Diseaselysophosphatidylcholine measurement

MGAM ZPR1 MGA

1.24e-03621003EFO_0010224
Diseaselymphocyte count

ROCK2 CYP2C19 RIPOR2 CYP2C9 RASA3 E2F2 NCOR1 ZNF800 ZNF644 PHLPP1 PPIP5K2 GOLGA3 NOTCH2

1.34e-03146410013EFO_0004587
DiseaseHypertriglyceridemia

LAMC1 ZPR1

1.87e-03191002EFO_0004211
Diseasehemoglobin A1 measurement

MGAM CYP2C19 SWAP70 SRGAP2 RP1L1 MGA NOTCH2

1.98e-035201007EFO_0007629
DiseaseCOVID-19, osteoarthritis

FYCO1 DPP9

2.08e-03201002MONDO_0005178, MONDO_0100096
Diseaseprogression free survival, ovarian serous carcinoma

MGAM MGA

2.51e-03221002EFO_0004920, EFO_1001516

Protein segments in the cluster

PeptideGeneStartEntry
TNMEQLLEKQGDGEA

MLLT6

701

P55198
QNQDLIAKMEEQGLA

ATXN10

431

Q9UBB4
KGDTLKILNMEDDQN

GRAPL

21

Q8TC17
QQELQKDKEAMALAN

FBXO10

411

Q9UK96
KGDTLKILNMEDDQN

GRAP

21

Q13588
QEANMGLLDEILKQE

AASS

116

Q9UDR5
MLLQQQLDDARNKAD

ANKRD36B

1166

Q8N2N9
KMLNSELENGKENQE

CCDC144CP

706

Q8IYA2
IQEMEGLKNNLKEQD

CCDC68

261

Q9H2F9
QKREQLIDMNAEGDE

DIAPH1

1181

O60610
GDDNLMQEINQNLAE

MTHFD1L

106

Q6UB35
SNGKLVEEIEQMNNL

TP53BP2

206

Q13625
TIQKDGLDNDVEQQM

ADAMTS12

811

P58397
LQEREFEANKLQGMQ

MLIP

106

Q5VWP3
AGEMIDNLLQDDQNI

RAD21L1

211

Q9H4I0
ENELQKMTRGQLQDE

ERC1

1061

Q8IUD2
LVEGESDNRNQQKME

MTA2

161

O94776
KLKDGENLENNMENL

RASA3

416

Q14644
DMNLNVINEGGIDKL

NIBAN2

371

Q96TA1
MLLQQQLDDARNKAD

ANKRD36C

1591

Q5JPF3
LLKNGANRDMQDNKE

NOTCH2

1996

Q04721
QDLLKNEQNQEEMTL

KIAA0825

101

Q8IV33
MEEKQQIILANQDGG

MGA

1

Q8IWI9
NDPDMKELNLNNIEN

LMOD3

251

Q0VAK6
DLNLMADNSQPENEK

FOXK2

231

Q01167
AAQEMQELGEKLQAL

FYCO1

396

Q9BQS8
NNLAFNEIKILGMEE

MGAM

1791

O43451
DNGNEDLAEILQIAM

GABPB1

146

Q06547
ELKKILANGQMNEQD

MAP2K5

151

Q13163
LAEQQEKMLINGESG

PDE5A

856

O76074
ENQELMKSLEGNLET

NES

631

P48681
QDLLEKGLEANNFAM

HM13

246

Q8TCT9
GMEELQAQLEKELQN

ALOX12

256

P18054
QLQGIEADMLDQEAA

GOLGA3

641

Q08378
GILDINFLINKMQED

IL9

26

P15248
NLAEMIQKGEQLFLE

SMPD4

516

Q9NXE4
AEENGNVQALLEMLK

HERC5

561

Q9UII4
NLELLREENGEKQAM

PIKFYVE

591

Q9Y2I7
IQIMDQNNFQEKLEG

DNAH1

941

Q9P2D7
AMDEIKSQELNLEGQ

EFCAB5

56

A4FU69
NMQGLTDDQIEELKL

CFAP298

61

P57076
LAQQQMQSDLDKADL

CROCC

381

Q5TZA2
DQQFLNLMEKLNENI

CYP2C19

191

P33261
GQELKELMNTEQALD

E2F2

211

Q14209
ELNGNQLMEKRETEG

GJA9

361

P57773
GALKNQMGQVEIEDQ

DPP9

691

Q86TI2
KQAQELVDENDGLKM

CEP89

306

Q96ST8
RQDMQEAQGEQKELS

CEP250

1086

Q9BV73
KILNLGNEGNQEMLQ

HEATR4

856

Q86WZ0
LAFLQELNEKMQQAD

IFIT2

436

P09913
LLQQGAELEMKDIQG

ANKS3

121

Q6ZW76
ANNIKMEAENLEQLI

LAMC1

1286

P11047
DLDNEVNNMLKQLQE

LAMC1

1456

P11047
NNEDLRNGLTEDMQK

CXorf38

281

Q8TB03
DGQNANNLELEEMER

HERPUD2

341

Q9BSE4
NQKMIELLADNINLG

HEATR1

661

Q9H583
DQQFLNLMEKLNENI

CYP2C9

191

P11712
NGKQNQERLEIEMES

CCDC144A

901

A2RUR9
VIEGLENNNKLTMLD

PPP1R7

266

Q15435
QLSMQDNIGELDLDK

KIFBP

326

Q96EK5
MQDLQKAQAELDDKQ

DNAH5

3441

Q8TE73
LRLEMPNEDQNENNE

RPUSD4

356

Q96CM3
QNEANAEALKEMLGD

RELL2

81

Q8NC24
QDFELNNELKMNVLN

RASGRF2

931

O14827
SLKQMNVGEDLENED

TAF1D

176

Q9H5J8
GLSNKENRLEENEMI

NPY5R

241

Q15761
GLSEQENNEKQMRQL

NCOR1

386

O75376
KNMNLEGSIQDLFEL

NEPRO

96

Q6NW34
LKDMALNIGNEIDAQ

SNAP23

166

O00161
RDLKAENLLLDNNMN

SIK2

141

Q9H0K1
ENLLLDNNMNIKIAD

SIK2

146

Q9H0K1
DLGDMLAALEKQQQA

SECISBP2L

491

Q93073
GQQLQDDLMKVLNEL

SRGAP2C

146

P0DJJ0
GQQLQDDLMKVLNEL

SRGAP2B

146

P0DMP2
MSNLQGKIEDEQALA

MYH4

1091

Q9Y623
TDQLGLEQDFEQKQM

ARHGAP35

136

Q9NRY4
NSDLQMLKEELEGLN

RHPN2

81

Q8IUC4
EQNLMEKLETLGINA

DZIP1

546

Q86YF9
QDLNQEVMNLDDILK

RIPOR2

626

Q9Y4F9
MNFIKEENLDGNLNE

CCDC110

291

Q8TBZ0
DENAKNSELNLVGMI

USP53

281

Q70EK8
FLELVQLKNLNMEND

PIK3R4

496

Q99570
QLKNLNMENDPNNEE

PIK3R4

501

Q99570
QNLQEKLAEEMLGLA

USE1

166

Q9NZ43
KSEAQLEELAQMGLN

RIN2

196

Q8WYP3
DQNEELGLNDMKTEG

ZPR1

436

O75312
NNIANINDDMLEGLE

TLR3

516

O15455
GLQDNDLLDQMAAEL

RP1L1

1546

Q8IWN7
GQQLQDDLMKVLNEL

SRGAP2

146

O75044
MEGQLNQDDSILKVA

AXL

551

P30530
QDKDQMDDLRAQILG

UBE2T

26

Q9NPD8
ERQDADGQMKELQDQ

ROCK2

851

O75116
DGQMKELQDQLEAEQ

ROCK2

856

O75116
DEINKELNQVMEQLG

SMC1A

471

Q14683
KQMGQEIGNELDEQN

STX8

166

Q9UNK0
QDEEMNILAKLNENL

TRIM60

206

Q495X7
LNVLNGLANNMDDLK

ZNF644

16

Q9H582
GLANNMDDLKINTDI

ZNF644

21

Q9H582
ELGLVQFKDLNMNVN

ATP6V0A4

31

Q9HBG4
LQMDDNLPDVNDKQS

ZNF800

96

Q2TB10
NKLGDLDAMIFNNIE

PHLPP1

841

O60346
LKEQALQEAMEQLEQ

SWAP70

491

Q9UH65
LMELGQNNDSEIEEN

PPIP5K2

441

O43314
QEELNKGMADIDIQD

ARHGAP21

1196

Q5T5U3
LQKMLDQAENELENG

ZRSR2

136

Q15696
EEKLIGLMNNEAAQE

VRK2

381

Q86Y07
LDGIKESMEQNAGQL

AK7

441

Q96M32
EAQQELQMLQKQLGE

PDE4DIP

1741

Q5VU43