Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	4 iron, 4 sulfur cluster binding	ERCC2 PRIM2 ETFDH NDUFS2	2.46e-05	47	72	4	GO:0051539
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP10B ATP9B ATP8B1	1.38e-04	28	72	3	GO:0140326
GeneOntologyMolecularFunction	iron-sulfur cluster binding	ERCC2 PRIM2 ETFDH NDUFS2	1.81e-04	78	72	4	GO:0051536
GeneOntologyMolecularFunction	phosphatidylcholine flippase activity	ATP10B ATP8B1	1.91e-04	6	72	2	GO:0140345
GeneOntologyMolecularFunction	metal cluster binding	ERCC2 PRIM2 ETFDH NDUFS2	2.30e-04	83	72	4	GO:0051540
GeneOntologyMolecularFunction	molecular sensor activity	EFCAB9 TRPA1 NDUFS2	7.80e-04	50	72	3	GO:0140299
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP10B ATP9B ATP8B1	8.27e-04	51	72	3	GO:0140303
MousePheno	aortic valve regurgitation	ADAMTS19 CPLANE1 PLCE1	1.69e-05	13	56	3	MP:0006047
MousePheno	abnormal aortic valve commissure morphology	ADAMTS19 PLCE1	4.72e-05	3	56	2	MP:0031166
MousePheno	semilunar valve regurgitation	ADAMTS19 CPLANE1 PLCE1	4.76e-05	18	56	3	MP:0006049
MousePheno	semilunar valve stenosis	ADAMTS19 CPLANE1 PLCE1	1.48e-04	26	56	3	MP:0031585
MousePheno	cardiac valve regurgitation	ADAMTS19 CPLANE1 PLCE1	1.48e-04	26	56	3	MP:0009384
Domain	P_typ_ATPase_c	ATP10B ATP9B ATP8B1	1.94e-05	14	72	3	IPR032630
Domain	P-type_ATPase_N	ATP10B ATP9B ATP8B1	1.94e-05	14	72	3	IPR032631
Domain	P-type_ATPase_IV	ATP10B ATP9B ATP8B1	1.94e-05	14	72	3	IPR006539
Domain	PhoLip_ATPase_C	ATP10B ATP9B ATP8B1	1.94e-05	14	72	3	PF16212
Domain	PhoLip_ATPase_N	ATP10B ATP9B ATP8B1	1.94e-05	14	72	3	PF16209
Domain	-	ATP10B ATP9B ATP8B1	2.51e-04	32	72	3	3.40.1110.10
Domain	-	ATP10B ATP9B ATP8B1	2.51e-04	32	72	3	2.70.150.10
Domain	ATPase_P-typ_cyto_domN	ATP10B ATP9B ATP8B1	3.29e-04	35	72	3	IPR023299
Domain	P_typ_ATPase	ATP10B ATP9B ATP8B1	3.58e-04	36	72	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP10B ATP9B ATP8B1	3.58e-04	36	72	3	IPR018303
Domain	ATPASE_E1_E2	ATP10B ATP9B ATP8B1	3.58e-04	36	72	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP10B ATP9B ATP8B1	3.88e-04	37	72	3	IPR008250
Domain	E1-E2_ATPase	ATP10B ATP9B ATP8B1	3.88e-04	37	72	3	PF00122
Domain	Quinoprot_gluc/sorb_DH	LRP1 TBL1X	9.43e-04	12	72	2	IPR011041
Domain	OLF	OLFML2A OLFML3	1.11e-03	13	72	2	PS51132
Domain	Olfac-like_dom	OLFML2A OLFML3	1.11e-03	13	72	2	IPR003112
Domain	OLF	OLFML2A OLFML3	1.11e-03	13	72	2	SM00284
Domain	OLF	OLFML2A OLFML3	1.11e-03	13	72	2	PF02191
Domain	-	ATP10B ATP9B ATP8B1	1.93e-03	64	72	3	3.40.50.1000
Domain	VWC_out	VWF CRIM1	2.40e-03	19	72	2	SM00215
Domain	HAD-like_dom	ATP10B ATP9B ATP8B1	3.52e-03	79	72	3	IPR023214
Domain	cEGF	LRP1 FBN3	4.49e-03	26	72	2	IPR026823
Domain	cEGF	LRP1 FBN3	4.49e-03	26	72	2	PF12662
Domain	VWC	VWF CRIM1	5.19e-03	28	72	2	PF00093
Pubmed	ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.	ATP10B ATP9B ATP8B1	1.85e-06	12	72	3	21914794
Pubmed	Differential expression of putative transbilayer amphipath transporters.	ATP10B ATP9B ATP8B1	2.40e-06	13	72	3	11015572
Pubmed	MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism.	ERCC2 PRIM2 NDUFS2	3.80e-06	15	72	3	22678361
Pubmed	KIAA1549 promotes the development and chemoresistance of colorectal cancer by upregulating ERCC2.	ERCC2 KIAA1549	4.23e-06	2	72	2	37140813
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	METTL13 RHBDL2 IKBKE INPP5B NTRK1 PANK4 TAS1R1 LYST OLFML3 TTLL7 AGTRAP	8.53e-06	1031	72	11	16710414
Pubmed	Shear stress-independent binding of von Willebrand factor-type 2B mutants p.R1306Q & p.V1316M to LRP1 explains their increased clearance.	VWF LRP1	1.27e-05	3	72	2	25728415
Pubmed	Tubulin polyglutamylation differentially regulates microtubule-interacting proteins.	ATAT1 TTLL7	1.27e-05	3	72	2	36636822
Pubmed	Recombinant von Willebrand factor-insight into structure and function through infusion studies in animals with severe von Willebrand disease.	VWF LRP1	1.27e-05	3	72	2	11992244
Pubmed	Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.	LRP1 PLCE1	1.27e-05	3	72	2	27322543
Pubmed	Genome-wide meta-analysis identifies new susceptibility loci for migraine.	FRMD4A PTPRD LRP1 ADARB2	2.14e-05	78	72	4	23793025
Pubmed	Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).	VWF PRKACG	2.53e-05	4	72	2	12361948
Pubmed	Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.	OLFML2A MYBBP1A PRICKLE2 TAB2 ATAT1 TTLL7	4.16e-05	305	72	6	21244100
Pubmed	Prickle1 promotes focal adhesion disassembly in cooperation with the CLASP-LL5β complex in migrating cells.	PRICKLE2 PHLDB2	4.21e-05	5	72	2	27378169
Pubmed	Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.	ATP9B ATP8B1	4.21e-05	5	72	2	9548971
Pubmed	Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics.	ATP10B ATP8B1	6.31e-05	6	72	2	25947375
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	GATD3 ETFDH PLEC CPLANE1 NDUFS2 DYNC1H1	6.54e-05	331	72	6	29199018
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	METTL13 WDHD1 UBR4 PANK4 LRP1 PRDM15 DYNC1H1 TTLL7 TBL1X	6.82e-05	857	72	9	25609649
Pubmed	Amotl2 interacts with LL5β, localizes to podosomes and regulates postsynaptic differentiation in muscle.	PLEC PHLDB2	8.82e-05	7	72	2	23525008
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPN3 ERCC2 B4GALNT4 UBR4 NPRL3 OGDHL PLEC LYST DYNC1H1 AGTRAP	9.04e-05	1105	72	10	35748872
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	GATD3 MYBBP1A METTL13 ERCC2 WDHD1 PRIM2 UBR4 DYNC1H1	1.04e-04	704	72	8	29955894
Pubmed	Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein.	TAB2 TBL1X	1.51e-04	9	72	2	12150997
Pubmed	Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth.	VWF HLA-C	1.51e-04	9	72	2	21300875
Pubmed	TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration.	VWF TAB2	1.88e-04	10	72	2	22972987
Pubmed	The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.	ATP9B ATP8B1	1.88e-04	10	72	2	15919184
Pubmed	IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway.	ERCC2 PRIM2	1.88e-04	10	72	2	23585563
Pubmed	Nucleolar proteome dynamics.	MYBBP1A ERCC2 ATR PLEC ADARB2 DYNC1H1	2.36e-04	419	72	6	15635413
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	EPN3 METTL13 HLA-C UBR4 NPRL3 TAB2 NDUFS2	2.55e-04	604	72	7	38803224
Pubmed	Novel association strategy with copy number variation for identifying new risk Loci of human diseases.	PTPRD INPP5B	2.75e-04	12	72	2	20808825
Pubmed	A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.	TAB2 DYNC1H1 PLCE1	2.81e-04	61	72	3	19875381
Pubmed	Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation.	TRPA1 NTRK1	3.25e-04	13	72	2	35904071
Pubmed	Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.	VWF PLEC	3.25e-04	13	72	2	22962592
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	HLA-C DYNC1H1	3.78e-04	14	72	2	9373155
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	EFCAB9 ATP10B CPLANE1	5.16e-04	75	72	3	15372022
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	TCF3 PLEC DYNC1H1	5.37e-04	76	72	3	27542412
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	ERCC2 PRIM2 LRP1 OGDHL GCDH NDUFS2 DYNC1H1	5.47e-04	686	72	7	28380382
Pubmed	New gene functions in megakaryopoiesis and platelet formation.	VWF ANKDD1A PLEC	6.46e-04	81	72	3	22139419
Pubmed	Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors.	TRPA1 NTRK1	7.06e-04	19	72	2	22787056
Pubmed	Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor.	TRPA1 NTRK1	7.06e-04	19	72	2	24516396
Pubmed	Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation.	TRPA1 NTRK1	7.84e-04	20	72	2	33789102
Pubmed	Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.	TRPA1 NTRK1	7.84e-04	20	72	2	35875660
Pubmed	Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.	ERCC2 ATR	7.84e-04	20	72	2	16195237
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	GATD3 MYBBP1A HLA-C ETFDH LRP1 OGDHL PLEC NDUFS2 OLFML3 LSM3	7.88e-04	1451	72	10	30550785
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMD4A UBR4 TAB2	7.96e-04	87	72	3	12465718
Pubmed	A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.	MYBBP1A PLEC	8.65e-04	21	72	2	24923560
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	TRPA1 NTRK1	8.65e-04	21	72	2	25369838
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	MYBBP1A ERCC2 UBR4 DYNC1H1	8.98e-04	206	72	4	22174317
Pubmed	Genome-wide, large-scale production of mutant mice by ENU mutagenesis.	ERCC2 DYNC1H1	9.50e-04	22	72	2	10932192
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	MYBBP1A GCDH NDUFS2 DYNC1H1	9.81e-04	211	72	4	17314511
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	ERCC2 CRIM1 LRP1 PLEC	1.03e-03	214	72	4	22199357
Pubmed	HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease.	PRKACG PLCE1	1.04e-03	23	72	2	9730685
Pubmed	Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.	TRPA1 NTRK1	1.04e-03	23	72	2	16446141
Pubmed	The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases.	PRKACG PLCE1	1.04e-03	23	72	2	9278385
Pubmed	A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.	UBR4 TAB2 ATP9B XPNPEP2	1.11e-03	218	72	4	19460752
Pubmed	A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.	TRPA1 NTRK1	1.13e-03	24	72	2	17553423
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GATD3 P4HTM VWF PTPRD CRIM1 UBR4 LRP1 PLEC DYNC1H1	1.31e-03	1285	72	9	35914814
Pubmed	Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non-small-cell lung cancer.	ERCC2 ATR	1.33e-03	26	72	2	20731661
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	FRMD4A GATD3 TRAPPC4 OGDHL ZNF221 XPNPEP2 PLEC ATAT1 OLFML3	1.37e-03	1293	72	9	15342556
Pubmed	Functional proteomics mapping of a human signaling pathway.	EPN3 VWF UBR4 LRP1 PLEC DYNC1H1	1.42e-03	591	72	6	15231748
Pubmed	Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.	PPM1L RASSF10	1.43e-03	27	72	2	34709416
Pubmed	Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation.	TCF3 NTRK1	1.43e-03	27	72	2	25885041
Pubmed	An integrative method for scoring candidate genes from association studies: application to warfarin dosing.	PCED1B VWF	1.43e-03	27	72	2	21044367
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYBBP1A PTPRD HLA-C PRIM2 PPM1L KIAA1549 TAB2 PPEF2	1.45e-03	1049	72	8	27880917
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	UBR4 GCDH PLEC DYNC1H1	1.46e-03	235	72	4	28378594
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	GATD3 OGDHL PLEC NDUFS2 DYNC1H1	1.51e-03	403	72	5	30562941
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	PTPRD CRIM1	1.54e-03	28	72	2	33953184
Pubmed	Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.	PRDM15 TTLL7	1.54e-03	28	72	2	23006423
Pubmed	Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.	UBR4 DYNC1H1	1.54e-03	28	72	2	35227662
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	METTL13 ERCC2 HLA-C PANK4 GCDH NDUFS2	1.61e-03	606	72	6	36538041
Pubmed	TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.	IKBKE TAB2	1.77e-03	30	72	2	30420664
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MYBBP1A RHBDL2 WDHD1 INPP5B OGDHL TAB2 PLEC CPLANE1	1.78e-03	1084	72	8	11544199
Pubmed	SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.	IKBKE TAB2	1.89e-03	31	72	2	27307491
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	VWF CRIM1 LRP1	1.91e-03	118	72	3	21078624
Pubmed	A pancreatic cancer-specific expression profile.	PLEC NDUFS2	2.01e-03	32	72	2	8895530
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	IKBKE ZNF629 TAB2 PLEC ATAT1 LYST PHLDB2	2.03e-03	861	72	7	36931259
GeneFamily	ATPase phospholipid transporting	ATP10B ATP9B ATP8B1	7.81e-06	15	48	3	1210
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PCED1B ADAMTS19 FRMD4A CRIM1 PRIM2 PRICKLE2 TTLL7 TBL1X	7.62e-10	188	72	8	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2\|Striatum / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 IKBKE TAS1R1 RASSF10 ATP10B	1.27e-08	98	72	6	7a62a77ca83153dacff4d02d6e32104227d0980d
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)\|Striatum / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 IKBKE TAS1R1 RASSF10 ATP10B	1.27e-08	98	72	6	26250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 IKBKE TAS1R1 RASSF10 ATP10B	1.27e-08	98	72	6	42875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF3 ASAP2 NTRK1 ADARB2 FBN3 TBL1X	4.43e-07	178	72	6	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TCF3 ASAP2 NTRK1 ADARB2 FBN3 TBL1X	4.73e-07	180	72	6	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A RHBDL2 PPM1L RASSF10 KIAA1549 ATAT1	4.89e-07	181	72	6	4e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A RHBDL2 PPM1L RASSF10 KIAA1549 ATAT1	4.89e-07	181	72	6	ad30c01290fb98adbd0caed301a584761212c977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD4A RHBDL2 PPM1L RASSF10 KIAA1549 ATAT1	4.89e-07	181	72	6	3a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 ATP8B1 PLCE1	5.22e-07	183	72	6	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 ATP8B1 PLCE1	5.22e-07	183	72	6	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 ATP8B1 PLCE1	5.38e-07	184	72	6	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNASE4 PRICKLE2 LRP1 GEM OLFML3 PHLDB2	7.56e-07	195	72	6	fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCell	5'-Adult-Appendix-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNASE4 PRICKLE2 LRP1 GEM OLFML3 PHLDB2	8.02e-07	197	72	6	b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	OLFML2A FRMD4A RNASE4 VWF PLEC LYST	8.76e-07	200	72	6	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TCF3 NTRK1 OGDHL FBN3 PLCE1	7.16e-06	165	72	5	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	7.82e-06	168	72	5	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2A ADAMTS19 PTPRD CRIM1 PLCE1	8.28e-06	170	72	5	60bbd738c12e64e483485586c30057304884f5a6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EPN3 HLA-C NTRK1 ZNF629 RASSF10	8.28e-06	170	72	5	be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.01e-05	177	72	5	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10 ATP10B	1.06e-05	84	72	4	db96d45e863d04a9b340c9229576d654dce85a3f
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10 ATP10B	1.06e-05	84	72	4	152807da52b50713fc6fed2b2bef5d5762e9c0da
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocyte.Tnr.Pdgfa_(Pdgfa)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10 ATP10B	1.06e-05	84	72	4	a88bdb8ea8a50df38fb740515d02aa87293e5d25
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10 ATP10B	1.11e-05	85	72	4	159b3ac93490c3e4918ea61f8ede7add9e63ca40
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.12e-05	181	72	5	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.12e-05	181	72	5	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ASAP2 NTRK1 OGDHL PHLDB2 TBL1X	1.15e-05	182	72	5	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF RASSF10 KIAA1549 PHLDB2 TTLL7	1.18e-05	183	72	5	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.18e-05	183	72	5	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.18e-05	183	72	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.18e-05	183	72	5	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.25e-05	185	72	5	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD CRIM1 PLCE1	1.25e-05	185	72	5	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASAP2 VWF CRIM1 ATP8B1 PHLDB2	1.28e-05	186	72	5	41f1674afc17661eccaa779cdeb663db5e45685d
ToppCell	droplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASAP2 VWF CRIM1 ATP8B1 PHLDB2	1.28e-05	186	72	5	aa006650cf21a2c51dfe1091681f67fdad939107
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PCED1B CRIM1 ATP8B1 GEM TTLL7	1.38e-05	189	72	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2A ADAMTS19 CRIM1 HLA-C PLCE1	1.42e-05	190	72	5	92710caaff05123cf8e909319d7ac441d9b31a66
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRICKLE2 XPNPEP2 GEM OLFML3 PHLDB2	1.49e-05	192	72	5	a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRICKLE2 XPNPEP2 GEM OLFML3 PHLDB2	1.49e-05	192	72	5	2143e1fad2e88b90d668e12af37b2092d379090f
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRICKLE2 XPNPEP2 GEM OLFML3 PHLDB2	1.49e-05	192	72	5	904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	PCED1B ASAP2 VWF CRIM1 ATP8B1	1.53e-05	193	72	5	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	PCED1B ASAP2 VWF HLA-C ATP8B1	1.57e-05	194	72	5	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A CRIM1 GEM PHLDB2 PLCE1	1.57e-05	194	72	5	b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|lung / Disease (COVID-19 only), tissue and cell type	CRIM1 ADARB2 GEM TTLL7 PLCE1	1.57e-05	194	72	5	5e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE4 PTPRD LRP1 GEM OLFML3	1.65e-05	196	72	5	61bee32ca299219f31a30b57124e44e85b798e9f
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CRIM1 ADARB2 GEM TTLL7 PLCE1	1.65e-05	196	72	5	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNASE4 PRICKLE2 LRP1 GEM OLFML3	1.69e-05	197	72	5	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	Bronchial_Biopsy-Mesenchymal-Smooth_muscle\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	OLFML2A VWF CRIM1 PPM1L PLCE1	1.69e-05	197	72	5	98f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_nonmyelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EPN3 OLFML2A FRMD4A B4GALNT4 ZNF221	1.69e-05	197	72	5	4a7ff67bb0754e034e6f2a1bd34cde86ee3ef899
ToppCell	PBMC-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	IKBKE UBR4 LRP1 PLEC AGTRAP	1.77e-05	199	72	5	ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRPA1 PRICKLE2 LRP1 GEM OLFML3	1.81e-05	200	72	5	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Tmem2_(Tmem2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10 ATP10B	2.36e-05	103	72	4	287e945ef2f9646f1ff4a4c50fe6e8a5e7fe0d92
ToppCell	tumor_Lung-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	FRMD4A HLA-C RASSF10 LYST	8.28e-05	142	72	4	eaf08a0dbacc9ebbd54e377922e76d8ba854dcb8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK1 FBN3 TBL1X PLCE1	9.22e-05	146	72	4	ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCell	368C-Fibroblasts-Fibroblast-H-\|368C / Donor, Lineage, Cell class and subclass (all cells)	WDHD1 TAS1R1 PRICKLE2 PRDM15	1.08e-04	152	72	4	dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCell	368C-Fibroblasts-Fibroblast-H\|368C / Donor, Lineage, Cell class and subclass (all cells)	WDHD1 TAS1R1 PRICKLE2 PRDM15	1.08e-04	152	72	4	9f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPA1 NTRK1 PANK4 TBL1X	1.22e-04	157	72	4	1e3a4a7193d95f09d71c2dfe704b8e626c6d9624
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 FBN3 TBL1X PLCE1	1.31e-04	160	72	4	903727c14e370e5705394240f0ef61fe3e0a4c25
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	PTPRD PPM1L PLEC DENND11	1.34e-04	161	72	4	347edb0de10850b7d16c40945751033289289c9b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2A B4GALNT4 ATP10B PLCE1	1.38e-04	162	72	4	d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2A B4GALNT4 ATP10B PLCE1	1.38e-04	162	72	4	5bbd7130d4dad9035e73a439dda568195c136f31
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2A B4GALNT4 ATP10B PLCE1	1.38e-04	162	72	4	eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	OLFML2A B4GALNT4 ATP10B PLCE1	1.38e-04	162	72	4	e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPA1 PPM1L GEM PLCE1	1.48e-04	165	72	4	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPA1 PPM1L GEM PLCE1	1.48e-04	165	72	4	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	OLFML2A FRMD4A ASAP2 ATP10B	1.48e-04	165	72	4	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF CRIM1 ANKDD1A ATP8B1	1.51e-04	166	72	4	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS19 PTPRD CRIM1 PLCE1	1.58e-04	168	72	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD PLCE1	1.58e-04	168	72	4	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	B4GALNT4 TAS1R1 OGDHL FBN3	1.62e-04	169	72	4	05e12524d68d409fed386ffad233305683b4575b
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	OLFML2A FRMD4A ASAP2 PLCE1	1.62e-04	169	72	4	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VWF PTPRD ATP8B1 OLFML3	1.66e-04	170	72	4	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCED1B METTL13 IKBKE PRIM2	1.66e-04	170	72	4	bda900c836e0f2c1d7b442beb50b672d025b2420
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 FBN3 TBL1X PLCE1	1.66e-04	170	72	4	36dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD PLCE1	1.73e-04	172	72	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD PLCE1	1.73e-04	172	72	4	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCED1B PTPRD KIAA1549 PHLDB2	1.77e-04	173	72	4	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A TAS1R1 ATP8B1 PLCE1	1.77e-04	173	72	4	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RNASE4 PTPRD CRIM1 PLCE1	1.77e-04	173	72	4	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A TAS1R1 ATP8B1 PLCE1	1.77e-04	173	72	4	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCED1B PTPRD KIAA1549 PHLDB2	1.81e-04	174	72	4	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	METTL13 RHBDL2 VWF PRDM15	1.81e-04	174	72	4	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RNASE4 PTPRD CRIM1 PLCE1	1.81e-04	174	72	4	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCED1B ADAMTS19 PTPRD PLCE1	1.81e-04	174	72	4	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS19 PTPRD CRIM1 PLCE1	1.85e-04	175	72	4	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RHBDL2 NTRK1 PPM1L PHLDB2	1.89e-04	176	72	4	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASAP2 NTRK1 FBN3 PLCE1	1.89e-04	176	72	4	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS19 PTPRD CRIM1 PLCE1	1.98e-04	178	72	4	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A TAS1R1 ATP8B1 PLCE1	1.98e-04	178	72	4	7467e5ab2fcb39cc4a2c7dd69722c91def3b6aea
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A INPP5B PPM1L PLCE1	2.02e-04	179	72	4	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS19 PTPRD CRIM1 PLCE1	2.02e-04	179	72	4	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRMD4A ATP8B1 GEM PLCE1	2.02e-04	179	72	4	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	VWF CRIM1 ATP8B1 LYST	2.02e-04	179	72	4	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OLFML2A INPP5B PPM1L PLCE1	2.02e-04	179	72	4	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10	2.08e-04	71	72	3	2220e1b02baa71961cfc85536bafeb313e588bf3
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Pik3r3_(Pdgfa)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FRMD4A RHBDL2 RASSF10	2.08e-04	71	72	3	cc5de8bbcfefa2bf93cc137c74b49a745d5da229
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFCAB9 RNASE4 PTPRD PLCE1	2.11e-04	181	72	4	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADARB2 FBN3 TBL1X PLCE1	2.11e-04	181	72	4	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EFCAB9 RNASE4 PTPRD PLCE1	2.11e-04	181	72	4	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNASE4 PRICKLE2 LRP1 OLFML3	2.15e-04	182	72	4	3dfa9187e9d2bab1d199079d29209c4648220ada
Disease	Antihypertensive use measurement	PCED1B ETFDH NPRL3 OLFML3 PHLDB2 PLCE1	4.02e-05	265	70	6	EFO_0009927
Disease	coronary artery disease	ASAP2 HLA-C PRIM2 NPRL3 LRP1 RASSF10 TAB2 ADARB2 GEM TBL1X PLCE1	1.10e-04	1194	70	11	EFO_0001645
Disease	migraine disorder	FRMD4A PTPRD INPP5B LRP1 ADARB2 PLCE1	2.06e-04	357	70	6	MONDO_0005277
Disease	electrocardiography	CRIM1 NPRL3 TAB2 PLEC GEM LSM3 PLCE1	2.62e-04	530	70	7	EFO_0004327
Disease	ovary epithelial cancer (is_implicated_in)	ERCC2 TAB2	3.01e-04	11	70	2	DOID:2152 (is_implicated_in)
Disease	serum metabolite measurement	TRPA1 CRIM1 HLA-C ETFDH NPRL3 GCDH DENND11 OLFML3 EPHA10	3.85e-04	945	70	9	EFO_0005653
Disease	preeclampsia, hypertension, pregnancy-induced	NPRL3 PLCE1	6.52e-04	16	70	2	EFO_0000668, MONDO_0024664
Disease	response to thioamide, Drug-induced agranulocytosis	HLA-C PHLDB2	6.52e-04	16	70	2	EFO_0007633, HP_0012235
Disease	cervical artery dissection	LRP1 PLCE1	7.37e-04	17	70	2	EFO_1000059
Disease	Precursor B-cell lymphoblastic leukemia	TCF3 HLA-C	1.13e-03	21	70	2	C1292769
Disease	Infiltrating duct carcinoma of female breast	ATR EPHA10	1.13e-03	21	70	2	C3165106
Disease	Glioma	ATR HLA-C NTRK1	1.18e-03	87	70	3	C0017638
Disease	peak expiratory flow	ASAP2 NPRL3 LRP1 TAB2 FBN3 PHLDB2	1.18e-03	498	70	6	EFO_0009718
Disease	Colorectal Carcinoma	TCF3 ERCC2 PTPRD PANK4 ETFDH LRP1 ADARB2	1.37e-03	702	70	7	C0009402
Disease	pulse pressure measurement	ASAP2 PTPRD CRIM1 INPP5B ANKDD1A ETFDH NPRL3 LRP1 GEM PLCE1	1.59e-03	1392	70	10	EFO_0005763
Disease	migraine disorder, pulse pressure measurement	LRP1 PLCE1	1.74e-03	26	70	2	EFO_0005763, MONDO_0005277
Disease	factor VIII measurement, von Willebrand factor measurement	VWF HLA-C	1.87e-03	27	70	2	EFO_0004629, EFO_0004630
Disease	glaucoma (biomarker_via_orthology)	NTRK1 GEM	2.02e-03	28	70	2	DOID:1686 (biomarker_via_orthology)
Disease	lifestyle measurement, depressive symptom measurement	FRMD4A ATP8B1 ADARB2	2.02e-03	105	70	3	EFO_0007006, EFO_0010724
Disease	immature platelet count	VWF ANKDD1A PLEC	2.07e-03	106	70	3	EFO_0803544
Disease	Strabismus	PTPRD ADARB2	2.16e-03	29	70	2	HP_0000486
Disease	right ventricular ejection fraction measurement	PLEC LSM3	2.31e-03	30	70	2	EFO_0021816
Disease	esophageal carcinoma	RASSF10 PLCE1	2.31e-03	30	70	2	EFO_0002916

Protein segments in the cluster

Peptide	Gene	Start	Entry
MANGAGAVVHHQRDR	EPN3	266	Q9H201
IVRGNEQGFFRMHHL	FBN3	2741	Q75N90
HARMENQRNRGGVYA	ATP8B1	766	O43520
QGHYRQRSMGHRESS	ATP10B	516	O94823
YQGEGAHHIMRAIRQ	P4HTM	281	Q9NXG6
HLDRMRRHGVNYVQD	RASSF10	261	A6NK89
HRMEGVGQLPASYRH	ADARB2	601	Q9NS39
DTMAITGHPHRVYRQ	ADAMTS19	261	Q8TE59
GQQHHLVEYMERRLA	OLFML3	21	Q9NRN5
ADGRHLMVQKEPHQY	GEM	26	P55040
AGRREATHMLGHQEY	KIAA1549	1861	Q9HCM3
YMRHGDLNRFLRSHG	NTRK1	591	P04629
ARYDGSGHMEVLRGH	LRP1	1461	Q07954
GIHRELGVHYSRMQS	ASAP2	461	O43150
RHIGRLLMVHGRNSY	ATP9B	911	O43861
TALHYIHDGIGAMVR	GATD3B	246	A0A0B4J2D5
AGMNHLRENGIVHRD	IKBKE	121	Q14164
NHLEGQFMYRHSRPV	EFCAB9	96	A8MZ26
GQEQRYTCHMQHEGL	HLA-C	276	P10321
YHLGMYHERINRVTN	OGDHL	336	Q9ULD0
QRGHMHNGLNYREVR	PCED1B	66	Q96HM7
RGRHHLEEIMYNENT	NPRL3	521	Q12980
GRLHAYDQHLNMILG	LSM3	41	P62310
EGIDFVHHYGRAVIM	ERCC2	606	P18074
LSEMGYVHRGLAARH	EPHA10	761	Q5JZY3
LHLVMQGDVIRHYGE	MYBBP1A	321	Q9BQG0
RMHAAYIRPGGVHQD	NDUFS2	221	O75306
VVIEGMGRAVHTNYH	PANK4	721	Q9NVE7
VHFGNHVVMNRREFG	LGALS13	56	Q9UHV8
RENHHLRHGGRMQYG	PRIM2	296	P49643
NPIGYRDLQSHGRMH	PRICKLE2	626	Q7Z3G6
QSLEGLRQMHYHRND	FRMD4A	586	Q9P2Q2
MNNHGNYIVRLGHLV	ETFDH	166	Q16134
LVYLHRRNVMGHAVE	ATR	156	Q13535
GRVMLVRHQETGGHY	PRKACG	56	P22612
QAMGTSRIQHYSGRH	CPLANE1	2871	Q9H799
GNGISDEYHVIRHAM	GCDH	391	Q92947
LENQVRHQLEMPGHY	DENND11	171	A4D1U4
DMGHLQVDYRDNRLH	CRIM1	916	Q9NZV1
ETHMATLGQYLVHGR	LYST	36	Q99698
QRHGHGRELFQYMLQ	ATAT1	131	Q5SQI0
TALHYIHDGIGAMVR	GATD3	246	P0DPI2
GGQEHALFLYTHRRM	INPP5B	46	P32019
VAFNRVARGMLHQDH	DYNC1H1	3866	Q14204
VALHRGQQYESMDHI	METTL13	336	Q8N6R0
LNRGNHEDHMVNLRY	PPEF2	236	O14830
EQLRHYENHSAIMLG	OLFML2A	176	Q68BL7
HGQIRGYQVHYVRME	PTPRD	741	P23468
HAVLAINGMDVNGRY	TRAPPC4	61	Q9Y296
YMLVHAGVQHILGNL	RHBDL2	126	Q9NX52
NIYHHGREGSRMNGS	TAB2	86	Q9NYJ8
RNHQHGLPQRQFYEM	PLCE1	111	Q9P212
HTLYRGHQAALGLME	SCRN2	356	Q96FV2
HVHTQAGQGMRGYED	PRDM15	351	P57071
HNVAVYSIQGRRDHM	PPM1L	91	Q5SGD2
LRGYNHQQMSEGHRQ	PHLDB2	956	Q86SQ0
VTAQYMERLNARHGG	B4GALNT4	721	Q76KP1
GTRSYQEHGHRMLLI	ANKDD1A	451	Q495B1
VYHMYRERGGELLVH	AGTRAP	106	Q6RW13
AGRGAMQSVLHHFQR	TBL1X	16	O60907
GMYQRFLRQHVHPEE	RNASE4	31	P34096
IQRHRVMHSGDGPYK	ZNF20	186	P17024
GEEHGYSRQLHINFM	TRPA1	221	O75762
HGYHLFQAMRLGVEE	TAS1R1	71	Q7RTX1
NVYGAIMHEVRFNHL	VWF	2041	P04275
HERMGYQLHGAEVNG	TCF3	271	P15923
MAGHGEQLFIVYHRG	WDHD1	576	O75717
HPQGEQMYRRVYRLH	PLEC	601	Q15149
KFNLDMHQRVHGGER	ZNF221	546	Q9UK13
AHMNEYIGQHDERRA	XPNPEP2	76	O43895
EGIFMQHQRIHIGEN	ZNF629	581	Q9UEG4
ADRVYHQLMGHRPQL	UBR4	3746	Q5T4S7
ISREEHENRHMGNYR	TTLL7	441	Q6ZT98