Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA1 ERCC6 SMCHD1 KIF21A HSPH1 ATP1A2 MTREX HSPA5 ATP4B DDX1	1.54e-05	614	61	10	GO:0140657
GeneOntologyMolecularFunction	allyl-alcohol dehydrogenase activity	AKR1B15 AKR1B1	5.49e-05	4	61	2	GO:0047655
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA1 ERCC6 SMCHD1 KIF21A ATP1A2 MTREX HSPA5 DDX1	5.61e-05	441	61	8	GO:0016887
GeneOntologyMolecularFunction	cadherin binding	EPS15 EPS15L1 EEF1G EIF2S3 AHNAK FNBP1L HSPA5	7.59e-05	339	61	7	GO:0045296
GeneOntologyMolecularFunction	apolipoprotein A-I binding	ABCA1 SCARB1	9.13e-05	5	61	2	GO:0034186
GeneOntologyMolecularFunction	enzyme activator activity	ARFGAP2 ERCC6 PSME4 UBE2N DBF4B ARHGAP12 ARFGAP1 RICTOR ARHGAP45	1.59e-04	656	61	9	GO:0008047
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	UBE2A UBE2B UBE2N	1.96e-04	37	61	3	GO:0061631
GeneOntologyMolecularFunction	molecular function activator activity	VEGFC ARFGAP2 ERCC6 PSME4 UBE2N DBF4B ARHGAP12 ARFGAP1 PRKACA RICTOR ARHGAP45 ATP4B	3.02e-04	1233	61	12	GO:0140677
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	UBE2A UBE2B UBE2N	3.07e-04	43	61	3	GO:0061650
GeneOntologyMolecularFunction	ubiquitin binding	EPS15 UBE2A NSFL1C UBE2N	3.22e-04	107	61	4	GO:0043130
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A2 ATP4B	4.96e-04	11	61	2	GO:0008556
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCA1 ERCC6 EIF2S3 SMCHD1 KIF21A ATP1A2 MTREX HSPA5 DDX1	5.42e-04	775	61	9	GO:0017111
GeneOntologyMolecularFunction	ubiquitin-like protein binding	EPS15 UBE2A NSFL1C UBE2N	6.34e-04	128	61	4	GO:0032182
GeneOntologyMolecularFunction	lipid binding	ABCA1 NSFL1C SCARB1 AKR1B15 FNBP1L ATP1A2 ACBD6 SCIN MCTP2 GSN	7.61e-04	988	61	10	GO:0008289
GeneOntologyMolecularFunction	retinal dehydrogenase activity	AKR1B15 AKR1B1	8.16e-04	14	61	2	GO:0001758
GeneOntologyMolecularFunction	aldose reductase (NADPH) activity	AKR1B15 AKR1B1	8.16e-04	14	61	2	GO:0004032
GeneOntologyMolecularFunction	high-density lipoprotein particle binding	ABCA1 SCARB1	9.40e-04	15	61	2	GO:0008035
GeneOntologyMolecularFunction	all-trans-retinol dehydrogenase (NADP+) activity	AKR1B15 AKR1B1	9.40e-04	15	61	2	GO:0052650
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCA1 ERCC6 EIF2S3 SMCHD1 KIF21A ATP1A2 MTREX HSPA5 DDX1	9.53e-04	839	61	9	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCA1 ERCC6 EIF2S3 SMCHD1 KIF21A ATP1A2 MTREX HSPA5 DDX1	9.62e-04	840	61	9	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCA1 ERCC6 EIF2S3 SMCHD1 KIF21A ATP1A2 MTREX HSPA5 DDX1	9.62e-04	840	61	9	GO:0016818
GeneOntologyMolecularFunction	1-phosphatidylinositol binding	SCARB1 SCIN	1.21e-03	17	61	2	GO:0005545
GeneOntologyMolecularFunction	apolipoprotein binding	ABCA1 SCARB1	1.68e-03	20	61	2	GO:0034185
GeneOntologyMolecularFunction	cell adhesion molecule binding	EPS15 EPS15L1 EEF1G EIF2S3 AHNAK FNBP1L HSPA5	2.26e-03	599	61	7	GO:0050839
GeneOntologyMolecularFunction	alcohol dehydrogenase (NADP+) activity	AKR1B15 AKR1B1	3.07e-03	27	61	2	GO:0008106
GeneOntologyMolecularFunction	ubiquitin protein ligase binding	UBE2A UBE2B UBE2N PRKACA HSPA5	3.65e-03	337	61	5	GO:0031625
GeneOntologyMolecularFunction	aldo-keto reductase (NADPH) activity	AKR1B15 AKR1B1	4.29e-03	32	61	2	GO:0004033
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA1 ATP1A2 ATP4B	4.53e-03	109	61	3	GO:0042626
GeneOntologyMolecularFunction	ubiquitin-like protein ligase binding	UBE2A UBE2B UBE2N PRKACA HSPA5	4.71e-03	358	61	5	GO:0044389
GeneOntologyMolecularFunction	lipoprotein particle binding	ABCA1 SCARB1	5.12e-03	35	61	2	GO:0071813
GeneOntologyMolecularFunction	protein-lipid complex binding	ABCA1 SCARB1	5.12e-03	35	61	2	GO:0071814
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP1A2 ATP4B	5.41e-03	36	61	2	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP1A2 ATP4B	5.41e-03	36	61	2	GO:0015662
GeneOntologyMolecularFunction	phospholipid binding	ABCA1 NSFL1C SCARB1 SCIN MCTP2 GSN	6.44e-03	548	61	6	GO:0005543
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSPH1 HSPA5	6.65e-03	40	61	2	GO:0140662
GeneOntologyBiologicalProcess	maintenance of location	MEST ABCA1 SCARB1 PRKACA TACC3 ATP1A2 SCIN HSPA5 GSN	2.01e-06	396	60	9	GO:0051235
GeneOntologyCellularComponent	ubiquitin conjugating enzyme complex	UBE2A UBE2B UBE2N	1.96e-06	9	61	3	GO:0031371
GeneOntologyCellularComponent	HULC complex	UBE2A UBE2B	5.01e-05	4	61	2	GO:0033503
GeneOntologyCellularComponent	sex chromosome	UBE2A UBE2B SMCHD1	2.88e-04	44	61	3	GO:0000803
GeneOntologyCellularComponent	sodium:potassium-exchanging ATPase complex	ATP1A2 ATP4B	5.43e-04	12	61	2	GO:0005890
Domain	UBQ-conjugating_AS	UBE2A UBE2B UBE2N	7.24e-05	25	61	3	IPR023313
Domain	UQ_con	UBE2A UBE2B UBE2N	2.79e-04	39	61	3	PF00179
Domain	Villin/Gelsolin	SCIN GSN	2.90e-04	8	61	2	IPR007122
Domain	GEL	SCIN GSN	2.90e-04	8	61	2	SM00262
Domain	UBIQUITIN_CONJUGAT_1	UBE2A UBE2B UBE2N	3.00e-04	40	61	3	PS00183
Domain	UBQ-conjugat_E2	UBE2A UBE2B UBE2N	3.23e-04	41	61	3	IPR000608
Domain	UBIQUITIN_CONJUGAT_2	UBE2A UBE2B UBE2N	3.23e-04	41	61	3	PS50127
Domain	ALDOKETO_REDUCTASE_1	AKR1B15 AKR1B1	4.64e-04	10	61	2	PS00798
Domain	Aldo/ket_reductase_CS	AKR1B15 AKR1B1	4.64e-04	10	61	2	IPR018170
Domain	Aldo/keto_reductase	AKR1B15 AKR1B1	4.64e-04	10	61	2	IPR020471
Domain	EF-hand_4	EPS15 EPS15L1	4.64e-04	10	61	2	PF12763
Domain	ALDOKETO_REDUCTASE_2	AKR1B15 AKR1B1	4.64e-04	10	61	2	PS00062
Domain	ALDOKETO_REDUCTASE_3	AKR1B15 AKR1B1	4.64e-04	10	61	2	PS00063
Domain	EH	EPS15 EPS15L1	5.66e-04	11	61	2	PS50031
Domain	EH	EPS15 EPS15L1	5.66e-04	11	61	2	SM00027
Domain	EH_dom	EPS15 EPS15L1	5.66e-04	11	61	2	IPR000261
Domain	-	UBE2A UBE2B UBE2N	6.17e-04	51	61	3	3.10.110.10
Domain	-	HSPH1 HSPA5	6.78e-04	12	61	2	2.60.34.10
Domain	HSP70_peptide-bd	HSPH1 HSPA5	6.78e-04	12	61	2	IPR029047
Domain	UBQ-conjugating_enzyme/RWD	UBE2A UBE2B UBE2N	6.91e-04	53	61	3	IPR016135
Domain	-	HSPH1 HSPA5	8.00e-04	13	61	2	1.20.1270.10
Domain	Heat_shock_70_CS	HSPH1 HSPA5	8.00e-04	13	61	2	IPR018181
Domain	HSP70_C	HSPH1 HSPA5	8.00e-04	13	61	2	IPR029048
Domain	Gelsolin	SCIN GSN	9.31e-04	14	61	2	PF00626
Domain	Gelsolin-like_dom	SCIN GSN	9.31e-04	14	61	2	IPR007123
Domain	-	AKR1B15 AKR1B1	1.22e-03	16	61	2	3.20.20.100
Domain	HSP70	HSPH1 HSPA5	1.22e-03	16	61	2	PF00012
Domain	NADP_OxRdtase_dom	AKR1B15 AKR1B1	1.38e-03	17	61	2	IPR023210
Domain	HSP70_2	HSPH1 HSPA5	1.38e-03	17	61	2	PS00329
Domain	Aldo_ket_red	AKR1B15 AKR1B1	1.38e-03	17	61	2	PF00248
Domain	Aldo/ket_red/Kv-b	AKR1B15 AKR1B1	1.38e-03	17	61	2	IPR001395
Domain	HSP70_3	HSPH1 HSPA5	1.38e-03	17	61	2	PS01036
Domain	HSP70_1	HSPH1 HSPA5	1.38e-03	17	61	2	PS00297
Domain	Hsp_70_fam	HSPH1 HSPA5	1.55e-03	18	61	2	IPR013126
Domain	FCH	FNBP1L ARHGAP45	2.32e-03	22	61	2	SM00055
Domain	FCH_dom	FNBP1L ARHGAP45	2.54e-03	23	61	2	IPR001060
Domain	ADF-H/Gelsolin-like_dom	SCIN GSN	2.77e-03	24	61	2	IPR029006
Domain	-	SCIN GSN	2.77e-03	24	61	2	3.40.20.10
Domain	F_BAR	FNBP1L ARHGAP45	3.00e-03	25	61	2	IPR031160
Domain	F_BAR	FNBP1L ARHGAP45	3.00e-03	25	61	2	PS51741
Domain	ArfGap	ARFGAP2 ARFGAP1	4.02e-03	29	61	2	SM00105
Domain	ArfGap	ARFGAP2 ARFGAP1	4.02e-03	29	61	2	PF01412
Domain	ARFGAP	ARFGAP2 ARFGAP1	4.02e-03	29	61	2	PS50115
Domain	ArfGAP	ARFGAP2 ARFGAP1	4.02e-03	29	61	2	IPR001164
Domain	Helicase_C	ERCC6 MTREX DDX1	5.17e-03	107	61	3	PF00271
Domain	HELICc	ERCC6 MTREX DDX1	5.17e-03	107	61	3	SM00490
Domain	Helicase_C	ERCC6 MTREX DDX1	5.31e-03	108	61	3	IPR001650
Domain	HELICASE_CTER	ERCC6 MTREX DDX1	5.44e-03	109	61	3	PS51194
Domain	HELICASE_ATP_BIND_1	ERCC6 MTREX DDX1	5.44e-03	109	61	3	PS51192
Domain	DEXDc	ERCC6 MTREX DDX1	5.44e-03	109	61	3	SM00487
Domain	Helicase_ATP-bd	ERCC6 MTREX DDX1	5.58e-03	110	61	3	IPR014001
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EPS15 ARFGAP2 EPS15L1 EEF1G NSFL1C EIF2S3 AHNAK ARHGAP12 EGLN1 HSPH1 ARFGAP1 RICTOR RAI14 HSPA5	1.72e-11	708	61	14	39231216
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	EPS15 EPS15L1 EEF1G PDPR UBE2N AHNAK KIF21A HSPH1 ARFGAP1 PYGL RAI14 FNBP1L TACC3 NSUN2 HSPA5 GSN	1.14e-09	1367	61	16	32687490
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EPS15 ARFGAP2 EPS15L1 EEF1G NSFL1C EIF2S3 AHNAK SCARB1 RAI14 FNBP1L HSPA5	3.79e-09	565	61	11	25468996
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CCDC134 MEST EEF1G UBE2B UBE2N EIF2S3 SMCHD1 AHNAK KIF21A SCARB1 HSPH1 ARFGAP1 PRKACA RAI14 HSPA5	4.87e-09	1297	61	15	33545068
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	EPS15 ARFGAP2 EPS15L1 EEF1G NSFL1C AHNAK HSPH1 ARFGAP1 SLC33A1 HSPA5	5.83e-09	449	61	10	31732153
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GPALPP1 EPS15 EPS15L1 EEF1G EIF2S3 SMCHD1 AHNAK EGLN1 HSPH1 ARFGAP1 RAI14 SCIN NSUN2	6.94e-09	934	61	13	33916271
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EEF1G ERCC6 PSME4 NSFL1C SMCHD1 AHNAK KIF21A HSPH1 PYGL RICTOR RAI14 MTREX NSUN2 HSPA5 DDX1	8.58e-09	1353	61	15	29467282
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	EPS15 EEF1G NSFL1C EIF2S3 AHNAK HSPH1 PRKACA PYGL RAI14 AKR1B1 NSUN2 HSPA5 DDX1 GSN	9.02e-09	1149	61	14	35446349
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	PHF2 EPS15L1 EEF1G EIF2S3 KIF21A HSPH1 ARFGAP1 PRKACA PYGL HSPA5 GSN	1.00e-08	621	61	11	22794259
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	EPS15 EPS15L1 EEF1G PSME4 NSFL1C EIF2S3 AHNAK KIF21A HSPH1 ARFGAP1 PRKACA PYGL NSUN2 HSPA5 DDX1	2.25e-08	1455	61	15	22863883
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	GPALPP1 PHF2 EEF1G NSFL1C EIF2S3 SMCHD1 HSPH1 PYGL MTREX NSUN2 DDX1 GSN RAI1	4.90e-08	1103	61	13	34189442
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	GPALPP1 PHF2 EEF1G NSFL1C UBE2N EIF2S3 SMCHD1 AHNAK HSPH1 PYGL MTREX NSUN2 HSPA5 DDX1	5.00e-08	1318	61	14	30463901
Pubmed	Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells.	EEF1G EIF2S3 PRKACA HSPA5 DDX1	9.13e-08	63	61	5	17220478
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	EPS15 ARFGAP2 EPS15L1 EEF1G EIF2S3 AHNAK EGLN1 ARFGAP1 RICTOR RAI14 TACC3	9.76e-08	777	61	11	35844135
Pubmed	Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase.	UBE2A UBE2B UBE2N	1.02e-07	6	61	3	15383616
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	GPALPP1 PHF2 EPS15L1 NSFL1C SMCHD1 AHNAK RAI14 AKR1B1 MED13 RAI1	1.73e-07	645	61	10	25281560
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	EEF1G NSFL1C UBE2N EIF2S3 KIF21A HSPH1 RAI14 TEAD3 MTREX NSUN2 HSPA5 MED13 DDX1	2.01e-07	1247	61	13	27684187
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PDPR PSME4 SMCHD1 KIF21A RAI14 ATP1A2 MTREX MED13 RAI1	3.50e-07	529	61	9	14621295
Pubmed	Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis.	EEF1G EIF2S3 AHNAK AKR1B1 NSUN2 HSPA5	3.75e-07	159	61	6	36762613
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	EIF2S3 HSPH1 RAI14 MTREX NSUN2 HSPA5 DDX1	5.29e-07	274	61	7	34244482
Pubmed	MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.	HSPH1 PYGL AKR1B1 NSUN2 HSPA5 GSN	8.27e-07	182	61	6	30711629
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	EEF1G UBE2N EIF2S3 SMCHD1 AHNAK KIF21A HSPH1 FNBP1L MTREX NSUN2 HSPA5 DDX1 GSN	8.41e-07	1415	61	13	28515276
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GPALPP1 SMCHD1 AHNAK KIF21A ARHGAP12 HSPH1 PRKACA FNBP1L ATP1A2 HSPA5 MED13 DDX1 RAI1	1.04e-06	1442	61	13	35575683
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	AHNAK RICTOR RAI14 AKR1B1 NSUN2 HSPA5 GSN	1.26e-06	312	61	7	37120454
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	GPALPP1 CCDC134 ARFGAP2 EPS15L1 NSFL1C SCARB1 ARFGAP1 ATP1A2 SLC33A1 HSPA5 DDX1	1.26e-06	1007	61	11	34597346
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	EEF1G NSFL1C UBE2N EIF2S3 AHNAK HSPH1 NSUN2 HSPA5 DDX1 GSN	1.27e-06	803	61	10	36517590
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	EEF1G EIF2S3 AHNAK HSPH1 PRKACA RICTOR NSUN2 HSPA5 DDX1 GSN	1.33e-06	807	61	10	30575818
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	EEF1G UBE2A UBE2N SMCHD1 AHNAK PYGL MTREX AKR1B1 NSUN2 MED13 DDX1	1.35e-06	1014	61	11	32416067
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	EIF2S3 HSPH1 PRKACA MTREX NSUN2 HSPA5 DDX1	1.37e-06	316	61	7	31665637
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	EEF1G ERCC6 EIF2S3 SMCHD1 AHNAK HSPH1 RAI14 MTREX NSUN2 HSPA5 DDX1 GSN	1.60e-06	1257	61	12	36526897
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	EEF1G EIF2S3 AHNAK RAI14 AKR1B1 HSPA5 DDX1	1.83e-06	330	61	7	32529326
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	EEF1G UBE2N AHNAK HSPH1 HSPA5 DDX1	1.90e-06	210	61	6	26217791
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ARFGAP2 THNSL1 PSME4 EIF2S3 RICTOR MTREX NSUN2 SLC33A1 DDX1	1.92e-06	650	61	9	38777146
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	EEF1G EIF2S3 AHNAK HSPH1 NSUN2 HSPA5 DDX1 GSN	2.18e-06	488	61	8	31324722
Pubmed	Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.	EEF1G EIF2S3 AHNAK HSPH1 MTREX HSPA5	2.69e-06	223	61	6	20020773
Pubmed	Host HDL biogenesis machinery is recruited to the inclusion of Chlamydia trachomatis-infected cells and regulates chlamydial growth.	ABCA1 SCARB1	3.03e-06	2	61	2	22672264
Pubmed	Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport.	ABCA1 SCARB1	3.03e-06	2	61	2	21859969
Pubmed	The actin-binding proteins adseverin and gelsolin are both highly expressed but differentially localized in kidney and intestine.	SCIN GSN	3.03e-06	2	61	2	9819354
Pubmed	Impact of android overweight or obesity and insulin resistance on basal and postprandial SR-BI and ABCA1-mediated serum cholesterol efflux capacities.	ABCA1 SCARB1	3.03e-06	2	61	2	19837407
Pubmed	RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.	UBE2A UBE2B	3.03e-06	2	61	2	28806395
Pubmed	The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.	UBE2A UBE2B	3.03e-06	2	61	2	15169909
Pubmed	Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein.	ABCA1 SCARB1	3.03e-06	2	61	2	22802462
Pubmed	Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.	UBE2A UBE2B	3.03e-06	2	61	2	12556476
Pubmed	Impairment of the ABCA1 and SR-BI-mediated cholesterol efflux pathways and HDL anti-inflammatory activity in Alzheimer's disease.	ABCA1 SCARB1	3.03e-06	2	61	2	22178419
Pubmed	Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide.	ABCA1 SCARB1	3.03e-06	2	61	2	15102890
Pubmed	Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.	UBE2A UBE2B	3.03e-06	2	61	2	1717990
Pubmed	15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages.	ABCA1 SCARB1	3.03e-06	2	61	2	16647293
Pubmed	Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux.	ABCA1 PRKACA	3.03e-06	2	61	2	12196520
Pubmed	Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.	UBE2A UBE2B	3.03e-06	2	61	2	1559696
Pubmed	The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.	UBE2A UBE2B	3.03e-06	2	61	2	11885984
Pubmed	The polyphenol PGG enhances expression of SR-BI and ABCA1 in J774 and THP-1 macrophages.	ABCA1 SCARB1	3.03e-06	2	61	2	26322417
Pubmed	Hypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI.	ABCA1 SCARB1	3.03e-06	2	61	2	21840001
Pubmed	The crystal structure of the C-terminus of adseverin reveals the actin-binding interface.	SCIN GSN	3.03e-06	2	61	2	19666531
Pubmed	Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.	UBE2A UBE2B	3.03e-06	2	61	2	31683936
Pubmed	Relative contributions of ABCA1 and SR-BI to cholesterol efflux to serum from fibroblasts and macrophages.	ABCA1 SCARB1	3.03e-06	2	61	2	16410457
Pubmed	New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.	UBE2A UBE2B UBE2N	3.43e-06	17	61	3	26489670
Pubmed	Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor.	UBE2A UBE2B UBE2N	3.43e-06	17	61	3	33650289
Pubmed	Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method.	UBE2A UBE2B UBE2N	3.43e-06	17	61	3	36563856
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	EPS15 EEF1G UBE2N EIF2S3 SMCHD1 AHNAK NSUN2 HSPA5 DDX1	3.80e-06	707	61	9	19738201
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	ARFGAP2 EEF1G UBE2N EIF2S3 AHNAK HSPH1 HSPA5 DDX1	4.46e-06	538	61	8	28524877
Pubmed	Defining the membrane proteome of NK cells.	CCDC134 EPS15 EPS15L1 EEF1G AHNAK ARHGAP45 MCTP2 SLC33A1 HSPA5 MED13 DDX1	5.24e-06	1168	61	11	19946888
Pubmed	Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA.	EEF1G AHNAK HSPA5 GSN	5.35e-06	65	61	4	34645483
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	EEF1G EIF2S3 AHNAK HSPH1 RAI14 NSUN2 MCTP2 HSPA5 DDX1 GSN	5.58e-06	949	61	10	36574265
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	EEF1G EIF2S3 HSPH1 ATP1A2 NSUN2 DDX1	5.93e-06	256	61	6	35777956
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	EPS15L1 EIF2S3 AHNAK HSPH1 ARFGAP1 RAI14	5.93e-06	256	61	6	33397691
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPS15L1 EEF1G EIF2S3 HSPH1 PRKACA RAI14 BCAS1 ATP1A2 AKR1B1 HSPA5 DDX1 GSN	6.04e-06	1431	61	12	37142655
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	ARFGAP2 EPS15L1 AHNAK SCARB1 HSPH1 ARFGAP1 RAI14 SLC33A1	6.63e-06	568	61	8	37774976
Pubmed	ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase.	UBE2N PRKACA ATP1A2	7.72e-06	22	61	3	22797923
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	EEF1G EIF2S3 AHNAK HSPH1 NSUN2 HSPA5 DDX1 GSN	7.72e-06	580	61	8	35676659
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ZBTB7C UBE2N SMCHD1 AHNAK KIF21A MTREX HSPA5 DDX1	7.92e-06	582	61	8	20467437
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	EEF1G EIF2S3 SMCHD1 AHNAK HSPH1 ARFGAP1 MTREX NSUN2 HSPA5 DDX1	8.00e-06	989	61	10	36424410
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	PHF2 EEF1G EIF2S3 SMCHD1 NSUN2	8.27e-06	156	61	5	37108203
Pubmed	High-density lipoprotein-mediated transcellular cholesterol transport in mouse aortic endothelial cells.	ABCA1 SCARB1	9.07e-06	3	61	2	26255968
Pubmed	Cellular physiology of cholesterol efflux in vascular endothelial cells.	ABCA1 SCARB1	9.07e-06	3	61	2	15492319
Pubmed	Effect of resistance training on Na,K pump and Na+/H+ exchange protein densities in muscle from control and patients with type 2 diabetes.	ATP1A2 ATP4B	9.07e-06	3	61	2	14685860
Pubmed	RNF168 forms a functional complex with RAD6 during the DNA damage response.	UBE2A UBE2B	9.07e-06	3	61	2	23525009
Pubmed	Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse.	ABCA1 SCARB1	9.07e-06	3	61	2	17399905
Pubmed	Differential developmentally regulated expression of gelsolin family members in the mouse.	SCIN GSN	9.07e-06	3	61	2	10417819
Pubmed	ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines.	ABCA1 SCARB1	9.07e-06	3	61	2	17241464
Pubmed	The human RAD18 gene product interacts with HHR6A and HHR6B.	UBE2A UBE2B	9.07e-06	3	61	2	10908344
Pubmed	Lipoprotein (a) upregulates ABCA1 in liver cells via scavenger receptor-B1 through its oxidized phospholipids.	ABCA1 SCARB1	9.07e-06	3	61	2	25852127
Pubmed	Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking.	ARFGAP2 ARFGAP1	9.07e-06	3	61	2	19015319
Pubmed	Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI.	ABCA1 SCARB1	9.07e-06	3	61	2	17906976
Pubmed	Cellular cholesterol transport proteins in diabetic nephropathy.	ABCA1 SCARB1	9.07e-06	3	61	2	25181357
Pubmed	Effect of bariatric surgery-induced weight loss on SR-BI-, ABCG1-, and ABCA1-mediated cellular cholesterol efflux in obese women.	ABCA1 SCARB1	9.07e-06	3	61	2	21289254
Pubmed	Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo.	ABCA1 SCARB1	9.07e-06	3	61	2	17657311
Pubmed	Protein kinase A (PKA) phosphorylation of Na+/K+-ATPase opens intracellular C-terminal water pathway leading to third Na+-binding site in molecular dynamics simulations.	PRKACA ATP1A2	9.07e-06	3	61	2	22433860
Pubmed	Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.	AKR1B15 AKR1B1	9.07e-06	3	61	2	17381426
Pubmed	Determinants of leukocyte adenosine triphosphate-binding cassette transporter G1 gene expression in type 2 diabetes mellitus.	ABCA1 SCARB1	9.07e-06	3	61	2	18640393
Pubmed	ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.	ABCA1 SCARB1	9.07e-06	3	61	2	27377933
Pubmed	Hepatic Overexpression of Endothelial Lipase Lowers High-Density Lipoprotein but Maintains Reverse Cholesterol Transport in Mice: Role of Scavenger Receptor Class B Type I/ATP-Binding Cassette Transporter A1-Dependent Pathways.	ABCA1 SCARB1	9.07e-06	3	61	2	29748333
Pubmed	Three homologous ArfGAPs participate in coat protein I-mediated transport.	ARFGAP2 ARFGAP1	9.07e-06	3	61	2	19299515
Pubmed	The roles of different pathways in the release of cholesterol from macrophages.	ABCA1 SCARB1	9.07e-06	3	61	2	17761631
Pubmed	Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells.	UBE2A UBE2B	9.07e-06	3	61	2	12509447
Pubmed	Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects.	ABCA1 SCARB1	9.07e-06	3	61	2	18057374
Pubmed	Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.	ABCA1 SCARB1	9.07e-06	3	61	2	20018934
Pubmed	A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins.	EPS15 EPS15L1	9.07e-06	3	61	2	11919637
Pubmed	UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.	UBE2A UBE2B	9.07e-06	3	61	2	38182926
Pubmed	Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans.	ABCA1 SCARB1	9.07e-06	3	61	2	29853565
Pubmed	Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of ABCA1 and SR-BI in Bone marrow-derived cells in LDL receptor knockout mice on western-type diet.	ABCA1 SCARB1	9.07e-06	3	61	2	21071707
Interaction	KCNA3 interactions	EPS15 ARFGAP2 EPS15L1 EEF1G NSFL1C EIF2S3 AHNAK ARHGAP12 EGLN1 HSPH1 ARFGAP1 PYGL RICTOR RAI14 HSPA5	3.34e-08	871	61	15	int:KCNA3
Interaction	RPA4 interactions	EPS15 ARFGAP2 EEF1G PSME4 NSFL1C SMCHD1 AHNAK ARFGAP1 RICTOR HSPA5	9.46e-07	452	61	10	int:RPA4
Interaction	CAND1 interactions	ARFGAP2 EEF1G ERCC6 UBE2N EIF2S3 SCARB1 PRKACA RICTOR ATP1A2 MTREX NSUN2 HSPA5 DDX1	2.14e-06	894	61	13	int:CAND1
Interaction	CDH1 interactions	EPS15 ARFGAP2 EPS15L1 EEF1G NSFL1C EIF2S3 AHNAK SCARB1 RAI14 FNBP1L NSUN2 HSPA5	2.69e-06	768	61	12	int:CDH1
Interaction	TARDBP interactions	EEF1G NSFL1C EIF2S3 AHNAK HSPH1 RICTOR MTREX SCIN HSPA5 DDX1	3.32e-06	520	61	10	int:TARDBP
Interaction	NAA40 interactions	GPALPP1 EPS15 EPS15L1 EEF1G EIF2S3 SMCHD1 AHNAK EGLN1 HSPH1 ARFGAP1 RAI14 SCIN NSUN2	5.73e-06	978	61	13	int:NAA40
Interaction	BAP1 interactions	EPS15 EEF1G EFNA2 NSFL1C EIF2S3 AHNAK HSPH1 PRKACA PYGL RAI14 AKR1B1 NSUN2 HSPA5 DDX1 GSN	6.17e-06	1314	61	15	int:BAP1
Interaction	CALD1 interactions	EEF1G PRKACA RICTOR RAI14 TACC3 NSUN2 HSPA5	1.49e-05	265	61	7	int:CALD1
Interaction	CEBPA interactions	GPALPP1 PHF2 EEF1G NSFL1C EIF2S3 SMCHD1 HSPH1 PYGL MTREX NSUN2 HSPA5 DDX1 GSN RAI1	1.59e-05	1245	61	14	int:CEBPA
Interaction	PRPF8 interactions	EEF1G ABCA1 ERCC6 EIF2S3 AHNAK KIF21A MTREX NSUN2 HSPA5 MED13 GSN	1.85e-05	776	61	11	int:PRPF8
Interaction	NBN interactions	UBE2A UBE2B ERCC6 UBE2N RICTOR DDX1	1.89e-05	183	61	6	int:NBN
Interaction	YAP1 interactions	EPS15L1 EEF1G SMCHD1 AHNAK EGLN1 HSPH1 ARFGAP1 RAI14 TEAD3 ARHGAP45 HSPA5 DDX1 GSN	1.92e-05	1095	61	13	int:YAP1
Interaction	PCDH7 interactions	EEF1G EIF2S3 AHNAK TACC3 AKR1B1 NSUN2 HSPA5	2.08e-05	279	61	7	int:PCDH7
Interaction	TSHB interactions	SMCHD1 RICTOR HSPA5	2.08e-05	18	61	3	int:TSHB
Interaction	HTT interactions	PHF2 EPS15L1 EEF1G PSME4 EIF2S3 KIF21A HSPH1 ARFGAP1 PRKACA PYGL HSPA5 GSN	2.28e-05	949	61	12	int:HTT
Interaction	MAPT interactions	EEF1G NSFL1C UBE2N EIF2S3 AHNAK KIF21A HSPH1 PRKACA ATP1A2 AKR1B1 NSUN2 HSPA5 DDX1	2.41e-05	1119	61	13	int:MAPT
Interaction	MYO6 interactions	EPS15 EPS15L1 NSFL1C HSPH1 RICTOR ELF3 HSPA5 GSN	2.54e-05	398	61	8	int:MYO6
Interaction	VASP interactions	EPS15 UBE2N PRKACA RICTOR TACC3 DDX1 GSN	2.91e-05	294	61	7	int:VASP
Interaction	CDC42 interactions	MEST ARFGAP2 EEF1G ABCA1 NSFL1C AHNAK SCARB1 PRKACA RICTOR RAI14 FNBP1L SCIN AKR1B1 SLC33A1	3.14e-05	1323	61	14	int:CDC42
Interaction	MAP1B interactions	EEF1G DBF4B EIF2S3 HSPH1 RICTOR ATP1A2 NSUN2 HSPA5 DDX1	3.29e-05	539	61	9	int:MAP1B
Interaction	PINK1 interactions	EEF1G NSFL1C AHNAK PRKACA RICTOR RAI14 TACC3 AKR1B1 HSPA5 GSN	3.37e-05	679	61	10	int:PINK1
Interaction	VDAC1 interactions	MEST EEF1G AHNAK SCARB1 PRKACA RAI14 ATP1A2 HSPA5 GSN	3.44e-05	542	61	9	int:VDAC1
Interaction	GLDC interactions	EIF2S3 HSPH1 RAI14 MTREX NSUN2 HSPA5 DDX1	5.09e-05	321	61	7	int:GLDC
Interaction	GSK3B interactions	EEF1G NSFL1C HSPH1 PRKACA PYGL RICTOR AKR1B1 NSUN2 HSPA5 GSN RAI1	5.16e-05	868	61	11	int:GSK3B
Interaction	CARM1 interactions	ARFGAP2 THNSL1 HSPH1 ARFGAP1 RICTOR SLC33A1 HSPA5	5.50e-05	325	61	7	int:CARM1
Interaction	NR2C2 interactions	GPALPP1 PHF2 EEF1G NSFL1C UBE2N EIF2S3 SMCHD1 AHNAK HSPH1 PYGL MTREX NSUN2 HSPA5 DDX1	5.97e-05	1403	61	14	int:NR2C2
Interaction	MSN interactions	NSFL1C HSPH1 ARFGAP1 RICTOR AKR1B1 NSUN2 HSPA5	6.05e-05	330	61	7	int:MSN
Interaction	EEF1D interactions	EEF1G UBE2A AHNAK RICTOR ELF3 SLC33A1 HSPA5	6.41e-05	333	61	7	int:EEF1D
Interaction	FBXO43 interactions	EEF1G AHNAK HSPA5 GSN	7.46e-05	74	61	4	int:FBXO43
Interaction	COMMD3 interactions	AHNAK HSPH1 VPS26C DDX1	7.46e-05	74	61	4	int:COMMD3
Interaction	BRCA1 interactions	EEF1G ERCC6 UBE2N DBF4B SMCHD1 AHNAK HSPH1 ZBTB47 PYGL RICTOR TACC3 HSPA5 DDX1	7.52e-05	1249	61	13	int:BRCA1
Interaction	CEBPB interactions	EEF1G UBE2N EIF2S3 SMCHD1 AHNAK HSPH1 ARFGAP1 PYGL TACC3 MTREX AKR1B1 NSUN2 HSPA5 DDX1	8.08e-05	1443	61	14	int:CEBPB
Interaction	EED interactions	ARFGAP2 EPS15L1 EEF1G UBE2N EIF2S3 SMCHD1 HSPH1 RICTOR RAI14 MTREX NSUN2 HSPA5 DDX1 GSN	8.21e-05	1445	61	14	int:EED
Interaction	AKR1B1 interactions	PRKACA AKR1B15 RICTOR AKR1B1	1.06e-04	81	61	4	int:AKR1B1
Interaction	KRT17 interactions	EPS15 EEF1G DBF4B EIF2S3 RICTOR HSPA5	1.12e-04	252	61	6	int:KRT17
Interaction	ISG15 interactions	EEF1G NSFL1C UBE2N AHNAK ELF3 RAI14 DDX1 GSN	1.16e-04	494	61	8	int:ISG15
Interaction	LRRK2 interactions	UBE2N DBF4B AHNAK HSPH1 ARFGAP1 RAI14 AKR1B1 HSPA5	1.19e-04	496	61	8	int:LRRK2
Interaction	PPT1 interactions	EEF1G UBE2N AHNAK HSPH1 HSPA5 DDX1	1.23e-04	256	61	6	int:PPT1
Interaction	RNF40 interactions	EPS15L1 UBE2A UBE2B UBE2N NSUN2 HSPA5	1.36e-04	261	61	6	int:RNF40
Interaction	UBE2M interactions	ARFGAP2 EEF1G HSPH1 PYGL RICTOR ELF3 TACC3 SLC33A1 HSPA5	1.40e-04	651	61	9	int:UBE2M
Interaction	UBA1 interactions	UBE2A UBE2B UBE2N HSPH1 RICTOR SCIN NSUN2	1.46e-04	380	61	7	int:UBA1
Interaction	FLT4 interactions	VEGFC UBE2N EGLN1 HSPH1 NSUN2 HSPA5	1.71e-04	272	61	6	int:FLT4
Interaction	PSMD3 interactions	UBE2A ERCC6 PSME4 KIF21A HSPH1 RICTOR HSPA5	1.71e-04	390	61	7	int:PSMD3
Interaction	PALS2 interactions	ABCA1 VPS26C MTREX NSUN2	1.81e-04	93	61	4	int:PALS2
Interaction	NME1-NME2 interactions	EEF1G AKR1B15 AKR1B1 HSPA5	1.89e-04	94	61	4	int:NME1-NME2
Interaction	NUAK1 interactions	PRKACA RAI14 HSPA5 DDX1	2.05e-04	96	61	4	int:NUAK1
Interaction	RDX interactions	HSPH1 PRKACA RICTOR RAI14 AKR1B1 NSUN2	2.15e-04	284	61	6	int:RDX
Interaction	RNF168 interactions	UBE2N RAI14 TACC3 DDX1	2.22e-04	98	61	4	int:RNF168
Interaction	PLOD3 interactions	EEF1G THNSL1 AHNAK HSPA5 DDX1	2.30e-04	183	61	5	int:PLOD3
Interaction	AURKA interactions	EPS15 EPS15L1 UBE2N ARFGAP1 PRKACA PYGL TACC3 ARHGAP45 HSPA5	2.31e-04	696	61	9	int:AURKA
Interaction	DHFR2 interactions	EFNA2 NSFL1C EIF2S3 SCARB1 SLC33A1 HSPA5	2.37e-04	289	61	6	int:DHFR2
Interaction	EZR interactions	AHNAK EGLN1 HSPH1 ARFGAP1 PYGL RICTOR RAI14 AKR1B1	2.50e-04	553	61	8	int:EZR
Interaction	AHCY interactions	NSFL1C SMCHD1 AHNAK PRKACA PYGL NSUN2	2.55e-04	293	61	6	int:AHCY
Interaction	RNF38 interactions	UBE2N AHNAK RAI14 HSPA5	2.59e-04	102	61	4	int:RNF38
Interaction	FAM20C interactions	ARFGAP2 EEF1G ARFGAP1 SLC33A1 HSPA5	2.61e-04	188	61	5	int:FAM20C
Interaction	MIB1 interactions	DNAJB13 EPS15 ARFGAP2 EPS15L1 UBE2N MTREX	2.64e-04	295	61	6	int:MIB1
Interaction	LMTK3 interactions	EPS15 UBE2N AKR1B1 NSUN2	2.68e-04	103	61	4	int:LMTK3
Interaction	IFI16 interactions	EIF2S3 SMCHD1 HSPH1 PRKACA RAI14 MTREX NSUN2 HSPA5 DDX1	2.79e-04	714	61	9	int:IFI16
Interaction	SNCA interactions	MEST UBE2N SMCHD1 AHNAK KIF21A HSPH1 PYGL MTREX HSPA5	2.85e-04	716	61	9	int:SNCA
Interaction	LIMA1 interactions	EPS15 AHNAK HSPH1 RICTOR RAI14 HSPA5 GSN	3.05e-04	429	61	7	int:LIMA1
Interaction	EFTUD2 interactions	EEF1G UBE2N EIF2S3 SMCHD1 AHNAK KIF21A HSPH1 FNBP1L MTREX NSUN2 HSPA5 MED13 DDX1	3.30e-04	1449	61	13	int:EFTUD2
Interaction	UBQLN1 interactions	EPS15 EPS15L1 UBE2A UBE2B NSFL1C SMCHD1 RAI14	3.81e-04	445	61	7	int:UBQLN1
Interaction	SUMO2 interactions	EEF1G ERCC6 SMCHD1 AHNAK TEAD3 NSUN2 HSPA5 DDX1	3.91e-04	591	61	8	int:SUMO2
Interaction	FGD5 interactions	EEF1G AHNAK RAI14 HSPA5 GSN	4.06e-04	207	61	5	int:FGD5
Interaction	MYH9 interactions	EPS15 NSFL1C AHNAK HSPH1 PRKACA RICTOR RAI14 HSPA5 GSN	4.15e-04	754	61	9	int:MYH9
Interaction	NDN interactions	EEF1G EIF2S3 AHNAK RAI14 AKR1B1 HSPA5 DDX1	4.24e-04	453	61	7	int:NDN
Interaction	DPYSL2 interactions	EPS15 NSFL1C HSPH1 RICTOR SCIN RAI1	4.57e-04	327	61	6	int:DPYSL2
Interaction	AGR2 interactions	EEF1G EIF2S3 AHNAK HSPH1 PRKACA RICTOR NSUN2 HSPA5 DDX1 GSN	4.57e-04	934	61	10	int:AGR2
Interaction	INPPL1 interactions	EEF1G AHNAK ARFGAP1 AKR1B1 HSPA5	4.73e-04	214	61	5	int:INPPL1
Interaction	HSF1 interactions	ARFGAP2 EPS15L1 EEF1G SMCHD1 HSPH1 NSUN2 HSPA5 DDX1	4.77e-04	609	61	8	int:HSF1
Interaction	PHLPP1 interactions	EPS15L1 EIF2S3 AHNAK HSPH1 ARFGAP1 RAI14	5.03e-04	333	61	6	int:PHLPP1
Interaction	CDK2 interactions	EEF1G UBE2A UBE2N EIF2S3 AHNAK RAI14 HSPA5 DDX1 GSN	5.46e-04	783	61	9	int:CDK2
Interaction	SEC24A interactions	ARFGAP2 EPS15L1 UBE2B RICTOR TACC3	5.82e-04	224	61	5	int:SEC24A
Interaction	RAD23A interactions	EPS15 PSME4 UBE2N PYGL TACC3	5.82e-04	224	61	5	int:RAD23A
Interaction	RNF167 interactions	UBE2A UBE2B UBE2N	5.86e-04	54	61	3	int:RNF167
Interaction	BTF3 interactions	EEF1G EIF2S3 AHNAK EGLN1 HSPH1 RAI14 HSPA5 DDX1 GSN	6.31e-04	799	61	9	int:BTF3
Interaction	ARHGAP24 interactions	PYGL RAI14 MTREX NSUN2 HSPA5 DDX1 GSN	6.44e-04	486	61	7	int:ARHGAP24
Interaction	HK1 interactions	NSFL1C ARFGAP1 PRKACA PYGL RICTOR	7.09e-04	234	61	5	int:HK1
Interaction	NDRG1 interactions	EEF1G EIF2S3 PRKACA HSPA5 DDX1	7.22e-04	235	61	5	int:NDRG1
Interaction	AR interactions	SMCHD1 ELF3 TEAD3 MTREX NSUN2 HSPA5 MED13 DDX1 GSN RAI1	7.31e-04	992	61	10	int:AR
Interaction	TRIM23 interactions	EPS15 EPS15L1 EEF1G UBE2N EIF2S3 ARFGAP1	7.57e-04	360	61	6	int:TRIM23
Interaction	DHX15 interactions	UBE2A NSFL1C HSPH1 RICTOR MTREX HSPA5 DDX1	7.79e-04	502	61	7	int:DHX15
Interaction	RNF123 interactions	EEF1G UBE2A UBE2N AHNAK KIF21A HSPH1 TACC3 HSPA5 RAI1	7.86e-04	824	61	9	int:RNF123
Interaction	NCKIPSD interactions	EPS15L1 ZBTB47 HSPA5 GSN	7.90e-04	137	61	4	int:NCKIPSD
Interaction	AKR1B15 interactions	AKR1B15 AKR1B1	8.01e-04	14	61	2	int:AKR1B15
Interaction	KCTD13 interactions	EPS15L1 EEF1G NSFL1C EIF2S3 HSPH1 PRKACA RAI14 BCAS1 AKR1B1 HSPA5 DDX1 GSN	8.37e-04	1394	61	12	int:KCTD13
GeneFamily	Ubiquitin conjugating enzymes E2	UBE2A UBE2B UBE2N	1.74e-04	41	48	3	102
GeneFamily	Gelsolin/villins	SCIN GSN	1.91e-04	8	48	2	950
GeneFamily	Aldo-keto reductases	AKR1B15 AKR1B1	7.09e-04	15	48	2	399
GeneFamily	Heat shock 70kDa proteins	HSPH1 HSPA5	9.15e-04	17	48	2	583
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	FNBP1L ARHGAP45	1.69e-03	23	48	2	1288
GeneFamily	ArfGAPs	ARFGAP2 ARFGAP1	3.46e-03	33	48	2	395
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP12 ARHGAP45	7.80e-03	50	48	2	721
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN	EEF1G EIF2S3 AHNAK ARHGAP12 AKR1B15 ACBD6	7.17e-06	200	61	6	M4062
Coexpression	BUSSLINGER_GASTRIC_ISTHMUS_CELLS	ZBTB7C AHNAK HSPH1 ELF3 BCAS1 TACC3 HSPA5 GSN	1.07e-05	458	61	8	M40010
Coexpression	ISSAEVA_MLL2_TARGETS	AHNAK ELF3 ARHGAP45 GSN	1.25e-05	61	61	4	M2281
Coexpression	GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN	PHF2 EPS15 ERCC6 PSME4 RICTOR	4.41e-05	167	61	5	M361
Coexpression	GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN	ABCA1 AHNAK RICTOR ARHGAP45 MED13	6.81e-05	183	61	5	M8189
Coexpression	GSE3982_EOSINOPHIL_VS_NKCELL_UP	UBE2B EGLN1 PYGL FNBP1L TEAD3	9.87e-05	198	61	5	M5420
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN	EPS15 PSME4 EIF2S3 PYGL ARHGAP45	1.01e-04	199	61	5	M5251
Coexpression	GSE7460_CD8_TCELL_VS_TREG_ACT_DN	UBE2A EIF2S3 FNBP1L TACC3 DDX1	1.01e-04	199	61	5	M5684
Coexpression	GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP	ARFGAP2 UBE2B PYGL FNBP1L GSN	1.01e-04	199	61	5	M5620
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	VEGFC EPS15 SMCHD1 ARHGAP12 FNBP1L MTREX MED13	1.02e-04	466	61	7	M13522
Coexpression	GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN	DNAJB13 SMCHD1 AKR1B15 TACC3 DDX1	1.03e-04	200	61	5	M5052
Coexpression	GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP	ABCA1 ARHGAP12 PYGL RAI14 HSPA5	1.03e-04	200	61	5	M4568
Coexpression	GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN	MEST SCARB1 SCIN AKR1B1 GSN	1.03e-04	200	61	5	M6485
Coexpression	GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN	MEST AHNAK PRKACA TACC3 ACBD6	1.03e-04	200	61	5	M3607
Coexpression	GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN	ABCA1 ARHGAP12 VPS26C MCTP2 HSPA5	1.03e-04	200	61	5	M5600
Coexpression	GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN	VEGFC MEST UBE2B THNSL1 HSPA5	1.03e-04	200	61	5	M3895
Coexpression	TIEN_INTESTINE_PROBIOTICS_24HR_DN	EEF1G HSPH1 ELF3 MCTP2 HSPA5	1.45e-04	215	61	5	M19666
Coexpression	GAUTAM_EYE_CORNEA_TGFBI_HIGH_EPITHELIAL_CELLS	KIF21A ARHGAP12 HSPH1 ELF3	1.51e-04	115	61	4	M43621
Coexpression	BUSSLINGER_GASTRIC_MATURE_PIT_CELLS	ZBTB7C AHNAK ELF3 BCAS1 GSN	1.76e-04	224	61	5	M40013
ToppCell	NS-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	VEGFC KIF21A ELF3 RAI14 BCAS1 GSN	3.06e-07	198	61	6	4a481e1edb80b950c823ed926842cd5132cfb27f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB7C AHNAK BCAS1 SCIN GSN	2.62e-06	159	61	5	c9e093d7c1dca83f6546adaf3d874929e2cea612
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSME4 AHNAK ATP1A2 HSPA5 GSN	4.31e-06	176	61	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C ELF3 BCAS1 AKR1B1 MCTP2	4.81e-06	180	61	5	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	UBE2B HSPH1 RICTOR MTREX MED13	6.58e-06	192	61	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	11.5-Airway-Mesenchymal-Cartilage\|Airway / Age, Tissue, Lineage and Cell class	MEST PYGL ATP1A2 SCIN GSN	6.75e-06	193	61	5	d4779d92a4dd4b8b656383e6f4fce76d3bd70931
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	UBE2B HSPH1 RICTOR MTREX MED13	6.75e-06	193	61	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 BCAS1 SCIN	7.83e-06	199	61	5	1e693d7bb481bf03a943b460a69787229625d7b1
ToppCell	NS-critical-d_16-33-Epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF21A HSPH1 ELF3 BCAS1 GSN	7.83e-06	199	61	5	3b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	MEST DBF4B KIF21A ELF3 RAI14	8.02e-06	200	61	5	eac33be484dc443794e66e473f03e98406c2983e
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHNAK BCAS1 SCIN GSN	5.07e-05	148	61	4	f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CCDC134 MTREX AKR1B1 NSUN2	6.70e-05	159	61	4	03d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	ABCA1 EGLN1 PYGL MCTP2	7.03e-05	161	61	4	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	ABCA1 EGLN1 PYGL MCTP2	8.48e-05	169	61	4	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	TCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue\|TCGA-Stomach / Sample_Type by Project: Shred V9	AKR1B15 ATP1A2 ATP4B GSN	8.88e-05	171	61	4	0f8d038858a4618b4348becc26a618d43b10d9d6
ToppCell	3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AHNAK HSPH1 BCAS1 HSPA5	8.88e-05	171	61	4	0de81d12a8000f2c59cdb214e67dc526d18098fe
ToppCell	TCGA-Stomach-Solid_Tissue_Normal\|TCGA-Stomach / Sample_Type by Project: Shred V9	AKR1B15 ATP1A2 ATP4B GSN	8.88e-05	171	61	4	791d37fe94ff2820fb409bbd38b31799df700ba1
ToppCell	3'-Adult-Distal_Rectal-Epithelial-mature_enterocytic-Colonocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AHNAK HSPH1 BCAS1 HSPA5	8.88e-05	171	61	4	0597339618fb4d416d55c538eceb353218a55002
ToppCell	TCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue\|TCGA-Stomach / Sample_Type by Project: Shred V9	AKR1B15 ATP1A2 ATP4B GSN	8.88e-05	171	61	4	0bf36930bd7fc63691f48a15db93deb1dd937c10
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MEST ERCC6 TACC3 ARHGAP45	9.29e-05	173	61	4	506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell	droplet-Heart-nan-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 EIF2S3 ATP1A2 GSN	9.50e-05	174	61	4	cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AHNAK VPS26C MTREX ARHGAP45	1.01e-04	177	61	4	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AHNAK VPS26C MTREX ARHGAP45	1.01e-04	177	61	4	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	AHNAK VPS26C MTREX ARHGAP45	1.01e-04	177	61	4	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	AHNAK VPS26C MTREX ARHGAP45	1.01e-04	177	61	4	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	AHNAK VPS26C MTREX ARHGAP45	1.01e-04	177	61	4	d5aeda113afaa2425874394610344570c9078478
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC1\|lymph-node_spleen / Manually curated celltypes from each tissue	SCARB1 ZBTB47 ATP1A2 GSN	1.08e-04	180	61	4	a7db1f00566c9acab8b239cbf2e053fb3f2f6a0d
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	AHNAK VPS26C MTREX ARHGAP45	1.15e-04	183	61	4	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MEST ZBTB7C PCDHB4 SCIN	1.15e-04	183	61	4	351d575339038bd4a66f408da518c567444208e8
ToppCell	COVID_non-vent-Myeloid-Monocytic-Neutrophil\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SMCHD1 EGLN1 PYGL MCTP2	1.20e-04	185	61	4	2c89af7cdf5306b900a5b8ec4fdfb8210e5667ed
ToppCell	Influenza-Influenza_Severe-Myeloid-Neutrophil\|Influenza_Severe / Disease, condition lineage and cell class	ABCA1 EGLN1 PYGL MCTP2	1.23e-04	186	61	4	1dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMCHD1 HSPH1 RICTOR MED13	1.28e-04	188	61	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-SCAT-Fat-3m\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF1G ABCA1 MTREX HSPA5	1.28e-04	188	61	4	b8dff61240e5052c2fbf7f28b86fe41822df45b0
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MTREX HSPA5 GSN	1.31e-04	189	61	4	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MTREX HSPA5 GSN	1.31e-04	189	61	4	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MTREX HSPA5 GSN	1.31e-04	189	61	4	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 MTREX HSPA5 GSN	1.31e-04	189	61	4	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEST EPS15 ABCA1 AHNAK	1.33e-04	190	61	4	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PYGL ATP1A2 SCIN GSN	1.36e-04	191	61	4	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	NS-critical-d_16-33-Epithelial-Secretory-diff\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	VEGFC AHNAK ELF3 GSN	1.39e-04	192	61	4	02b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCell	facs-Lung-EPCAM-18m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP1A2 ARHGAP45 HSPA5 GSN	1.41e-04	193	61	4	b9ac74357435f2f24aaede62b2a1d31b5d96a12c
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB7C ELF3 BCAS1 GSN	1.44e-04	194	61	4	49cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJB13 ABCA1 HSPA5 GSN	1.44e-04	194	61	4	50c5fc349533281a426bc7227a8ea9eca8d11985
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZBTB7C ELF3 BCAS1 GSN	1.44e-04	194	61	4	fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell	facs-Brain_Myeloid-Cortex-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJB13 ABCA1 HSPA5 GSN	1.44e-04	194	61	4	1662b110f84584e75150df0ac970e7df82f26e7e
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DNAJB13 ABCA1 HSPA5 GSN	1.44e-04	194	61	4	b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCell	Control-Classical_Monocyte-cMono_2\|Control / Disease condition and Cell class	SMCHD1 AHNAK PYGL ARHGAP45	1.47e-04	195	61	4	0fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|COVID-19_Mild / Disease condition and Cell class	ABCA1 SMCHD1 RICTOR ARHGAP45	1.50e-04	196	61	4	3729d1444c65cad640377894decc64129bc3fd5b
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	AHNAK PYGL ARHGAP45 MCTP2	1.50e-04	196	61	4	15397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ABCA1 AHNAK ARHGAP45 GSN	1.50e-04	196	61	4	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	Non-neuronal-Dividing-Radial_Glia-early\|World / Primary Cells by Cluster	MEST ELF3 TACC3 HSPA5	1.50e-04	196	61	4	dd3c6ea5e4ebcc27064f16507de6db6dc8f86fa8
ToppCell	3'-GW_trimst-2-LargeIntestine\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AHNAK RAI14 HSPA5 GSN	1.50e-04	196	61	4	27a216af92100224818c91e298428bee25ab0af8
ToppCell	mild-Myeloid-Neutrophils_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SMCHD1 EGLN1 PYGL MCTP2	1.50e-04	196	61	4	9c351306b6aae68ed47d4cb1911957bf67f9e1ae
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_3\|COVID-19_Mild / Disease condition and Cell class	AHNAK PYGL ARHGAP45 MCTP2	1.50e-04	196	61	4	f245e929a286cb097130572e1027b4f01be8b04d
ToppCell	Non-neuronal-Dividing-Radial_Glia-early-1\|World / Primary Cells by Cluster	MEST ELF3 TACC3 HSPA5	1.50e-04	196	61	4	70fe6a1a6de891832aaa6276c985b326985e14db
ToppCell	MS-mono1\|MS / Condition, Cell_class and T cell subcluster	PYGL SCIN AKR1B1 GSN	1.53e-04	197	61	4	32be48ee2a1397ed8f1ee8e60067dd9a96bece39
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIF21A ELF3 RAI14 HSPA5	1.53e-04	197	61	4	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	MS-mono1-\|MS / Condition, Cell_class and T cell subcluster	PYGL SCIN AKR1B1 GSN	1.53e-04	197	61	4	4b038a193ecc1df65bcb608091c513ddafd6c818
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	MEST ABCA1 ARHGAP12 ATP1A2	1.53e-04	197	61	4	58b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MEST AHNAK HSPH1 HSPA5	1.53e-04	197	61	4	05e303fff86db31f7b742324c64980eb2b9cff9a
ToppCell	Control-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	SMCHD1 AHNAK ARHGAP45 HSPA5	1.53e-04	197	61	4	eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 SCIN	1.53e-04	197	61	4	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	ASK452-Epithelial-Transformed_epithelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	MEST HSPH1 ELF3 RAI14	1.53e-04	197	61	4	b22a79a5922c865a360e2afc5506a08a512fa76a
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	MEST ABCA1 ARHGAP12 ATP1A2	1.56e-04	198	61	4	a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF21A ELF3 BCAS1 GSN	1.56e-04	198	61	4	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EEF1G ZBTB7C ELF3 GSN	1.56e-04	198	61	4	3cc9e671f596ef0829684018e4257571fefb6267
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MEST AHNAK HSPH1 HSPA5	1.56e-04	198	61	4	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIF21A ELF3 RAI14 HSPA5	1.56e-04	198	61	4	aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 BCAS1	1.59e-04	199	61	4	8bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCell	critical-Epithelial\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KIF21A ELF3 BCAS1 GSN	1.59e-04	199	61	4	bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCell	Healthy_Control-Myeloid-Macrophages-FCN1-SPP1+\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ABCA1 AHNAK SCARB1 SCIN	1.59e-04	199	61	4	7437bc48a803ab8f153e5516a0aa0391ae3d97c7
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZBTB7C AHNAK KIF21A ELF3	1.59e-04	199	61	4	fbd39d34636137d1b877dd8815d58f124990136b
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF21A ELF3 BCAS1 GSN	1.59e-04	199	61	4	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	18-Airway-Mesenchymal-Cartilage\|Airway / Age, Tissue, Lineage and Cell class	MEST PYGL SCIN GSN	1.59e-04	199	61	4	f5d0aa4170367c080d3c2f01d9af3529762917fa
ToppCell	human_hepatoblastoma-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PSME4 HSPH1 ELF3 NSUN2	1.59e-04	199	61	4	e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCell	COVID-19-COVID-19_Mild-Myeloid-Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	SMCHD1 EGLN1 PYGL MCTP2	1.59e-04	199	61	4	9f6b6731186ef399f952a75879eba66fd8ed3494
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZBTB7C AHNAK KIF21A ELF3	1.59e-04	199	61	4	6977f939ddbc47d4921f36c0a61a205259fe1284
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 BCAS1	1.59e-04	199	61	4	0c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GPALPP1 KIF21A ELF3 HSPA5	1.59e-04	199	61	4	121de4e02585de3a3010398387c523bacf8ce546
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIF21A ELF3 RAI14 HSPA5	1.62e-04	200	61	4	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZBTB7C AHNAK KIF21A ELF3	1.62e-04	200	61	4	8c4c396e99be6131a8fa60d86214d561031b12bf
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ELF3 BCAS1 FNBP1L SCIN	1.62e-04	200	61	4	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SMCHD1 EGLN1 PYGL MCTP2	1.62e-04	200	61	4	6beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ELF3 BCAS1 FNBP1L MCTP2	1.62e-04	200	61	4	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	5'-Airway_Nasal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 BCAS1	1.62e-04	200	61	4	f6e967738b4f7b173d6e9977e305f77380dd6c8a
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 BCAS1	1.62e-04	200	61	4	b68d212159b9d04866ba02ff55c35be247805eec
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SMCHD1 EGLN1 PYGL MCTP2	1.62e-04	200	61	4	026495aa7f1e7528a01d9199475cfc393677fc60
ToppCell	5'-Airway_Nasal-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK KIF21A ELF3 BCAS1	1.62e-04	200	61	4	358d71329921451c7f5a56f1db0f9989af2299dc
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	CCDC134 PDPR AHNAK MCTP2	1.62e-04	200	61	4	fe772d98c461c973dfc082e1fc50117c27ced804
Computational	Genes in the cancer module 4.	UBE2A UBE2B UBE2N	1.26e-04	21	51	3	MODULE_4
Computational	Genes in the cancer module 82.	UBE2A UBE2B UBE2N	1.90e-04	24	51	3	MODULE_82
Disease	Pseudoaphakia	ERCC6 AKR1B1 SLC33A1	1.49e-05	24	59	3	C0524524
Disease	Lens Opacities	ERCC6 AKR1B1 SLC33A1	1.49e-05	24	59	3	C1510497
Disease	Cataract	ERCC6 AKR1B1 SLC33A1	5.62e-05	37	59	3	C0086543
Disease	alkaline phosphatase measurement	UBE2A AHNAK PYGL RAI14 BCAS1 FNBP1L SLC33A1 GSN RAI1	1.74e-04	1015	59	9	EFO_0004533
Disease	uric acid measurement	ABCA1 ARMCX6 RAI14 BCAS1 FNBP1L AKR1B1 DDX1	2.10e-04	610	59	7	EFO_0004761
Disease	Microcephaly	ERCC6 EIF2S3 ATP1A2	3.32e-04	67	59	3	C0025958
Disease	syndromic intellectual disability (implicated_via_orthology)	UBE2A UBE2B	4.63e-04	16	59	2	DOID:0050888 (implicated_via_orthology)
Disease	Arthrogryposis	ERCC6 ATP1A2	8.05e-04	21	59	2	C0003886
Disease	Carcinoma of lung	ERCC6 RICTOR	9.68e-04	23	59	2	C0684249
Disease	Alzheimer disease, high density lipoprotein cholesterol measurement	ABCA1 SCARB1	1.24e-03	26	59	2	EFO_0004612, MONDO_0004975
Disease	indole-3-propionate measurement	AKR1B15 DDX1	1.34e-03	27	59	2	EFO_0010501
Disease	colorectal adenocarcinoma (is_marker_for)	ERCC6 RICTOR	1.34e-03	27	59	2	DOID:0050861 (is_marker_for)
Disease	Child Development Disorders, Specific	ARFGAP1 SLC33A1	1.54e-03	29	59	2	C0085997
Disease	Child Development Deviations	ARFGAP1 SLC33A1	1.54e-03	29	59	2	C0085996
Disease	Developmental Disabilities	ARFGAP1 SLC33A1	1.65e-03	30	59	2	C0008073
Disease	fatty liver disease (biomarker_via_orthology)	ABCA1 HSPA5	1.99e-03	33	59	2	DOID:9452 (biomarker_via_orthology)
Disease	Intellectual Disability	EIF2S3 ACBD6 NSUN2 MED13 RAI1	1.99e-03	447	59	5	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFEGGTFKLELFLPE	UBE2N	46	P61088
FFLGPKFKKLQDEGS	SLC33A1	526	O00400
FKSDPFKGADPFKGD	EPS15L1	626	Q9UBC2
FKGADPFKGDPFQND	EPS15L1	631	Q9UBC2
SGDPFQSKKGFGDPF	EPS15L1	821	Q9UBC2
DLKPVQDFFGLAFPG	ABCA1	2151	O95477
KFSVPGFKAEGPEVD	AHNAK	756	Q09666
FGNTPPPQKKEDDFL	ARFGAP1	186	Q8N6T3
LFPSDGFRDCKKGDP	ELF3	226	P78545
PKYKDNPFSLGESFG	ARFGAP2	356	Q8N6H7
DFQEGDFFKDPLPEA	ASMT	231	P46597
NTPKPSFFDFEGKQK	ACBD6	81	Q9BR61
ADPNFGFEEGKPCFI	ATP4B	166	P51164
AEFDEGFKVPGFLFK	ERCC6	491	Q03468
KLLFAEPKDAGFPFS	ARMCX6	136	Q7L4S7
FKPGKEFFPLDESGN	AKR1B1	116	P15121
GKESVFFAEPPFKAE	RAI14	301	Q9P0K7
GGNAKDFSPGLFEDP	RAI1	676	Q7Z5J4
KLFGFKEDPFVFIPE	NSUN2	511	Q08J23
IPKFKGPGDTSNFDD	PRKACA	316	P17612
LDPGPGAGDFKKFER	ARHGAP45	631	Q92619
FDEDGDKPPDFLGKV	MCTP2	576	Q6DN12
AFDPFLGGKNFDEKL	HSPH1	226	Q92598
NFGEEEFKFPPKDGF	DDX1	241	Q92499
EFKFPPKDGFVALSK	DDX1	246	Q92499
LSGGFEKNPKPIFTE	PDPR	301	Q8NCN5
EDFVKPKGAFKAFTG	NSFL1C	241	Q9UNZ2
SGPIKDKNSFPFFAS	RICTOR	1076	Q6R327
SFGHFPGPEFLDVEK	ARHGAP12	176	Q8IWW6
GDSGTGEFKFLKPIF	PCDHB4	756	Q9Y5E5
NLPSGKFPRGFKFDT	ATP1A2	556	P50993
FKSGFEPPGDFPFED	FNBP1L	271	Q5T0N5
QFKSFPEISFLGPKD	DBF4B	246	Q8NFT6
FGPALPPGFKKQDDS	GPALPP1	91	Q8IXQ4
FPEGKAQFADIEPKF	EGLN1	346	Q9GZT9
PEDPTKKGDLFIFFD	DNAJB13	281	P59910
GGPLKFSEKFQLFTP	EFNA2	121	O43921
PEGGETPLFKQFFKN	GSN	381	P06396
RKFPAGKVPAFEGDD	EEF1G	51	P26641
VGSDPFKDDPFGKID	EPS15	626	P42566
FKDDPFGKIDPFGGD	EPS15	631	P42566
KEFFNGKEPSRGINP	HSPA5	376	P11021
GGEAPSKPKDSSFFD	BCAS1	181	O75363
ALDFLGFGFSDKPRP	MEST	101	Q5EB52
DDPNFIPFGGDTKSG	TACC3	411	Q9Y6A5
GKPEKFSFGLLDLPF	SMCHD1	821	A6NHR9
PGVFGALQNFKEDKP	PHF2	656	O75151
LPEGGETPIFKQFFK	SCIN	331	Q9Y6U3
PGMFPFKDKFGLFAE	SCARB1	196	Q8WTV0
DKFKDDPVGPFGQES	MED13	636	Q9UHV7
FKTGDDFFPKDDKGN	AKR1B15	116	C9JRZ8
PDGPFPQDEKLKDAF	CCDC134	91	Q9H6E4
GKEFGVATNTFFKPP	VEGFC	141	P49767
VDFEGTDEPIFGKKP	MTREX	66	P42285
PGEPQVFLGKDKAFT	KIF21A	36	Q7Z4S6
GLKELYEKGPPNAFF	TEAD3	281	Q99594
FGPEGTPFEDGTFKL	UBE2A	41	P49459
SDGGLFVPAKEFPKL	THNSL1	261	Q8IYQ7
GGFDKPPSEYFPIKD	PSME4	741	Q14997
TIGPAQPFFKEEKEG	ZBTB47	181	Q9UFB7
PNDFFKDMFPDLPGG	ZBTB7C	306	A1YPR0
IDNGFFSPKQPDLFK	PYGL	746	P06737
FGPEGTPFEDGTFKL	UBE2B	41	P63146
PGKFPSGKTEIPFEF	VPS26C	81	O14972
DEFPTDIPGTKGNFK	EIF2S3	111	P41091