Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionselenide, water dikinase activity

SEPHS2 SEPHS1

6.30e-0521592GO:0004756
GeneOntologyMolecularFunctionphosphotransferase activity, paired acceptors

SEPHS2 SEPHS1

6.30e-0521592GO:0016781
GeneOntologyMolecularFunctionrecombination hotspot binding

PRDM7 PRDM9

6.30e-0521592GO:0010844
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

AOC3 LOXL4 IL4I1

2.57e-04161593GO:0016641
GeneOntologyMolecularFunctioncalcium ion binding

TRPM4 AOAH PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16 AOC3 C1R NID1 FKBP7

3.26e-0474915916GO:0005509
GeneOntologyMolecularFunctionalpha-sialidase activity

NEU4 NEU3

3.74e-0441592GO:0016997
GeneOntologyMolecularFunctionexo-alpha-sialidase activity

NEU4 NEU3

3.74e-0441592GO:0004308
GeneOntologyMolecularFunctionlactoperoxidase activity

PXDN PXDNL

3.74e-0441592GO:0140825
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

AOC3 LOXL4 IL4I1

5.11e-04201593GO:0016638
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2B PRDM7 PRDM9

5.11e-04201593GO:0042800
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB3 PCDHB16

1.55e-07531587GO:0016339
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16 PLXNB3

2.14e-0718715811GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 ITGAL PCDHB16 PLXNB3

5.52e-0631315812GO:0098742
GeneOntologyBiologicalProcessalpha-amino acid biosynthetic process

SDSL CAD HAO1 SEPHS2 SEPHS1 AASS

2.78e-05771586GO:1901607
GeneOntologyBiologicalProcessamino acid biosynthetic process

SDSL CAD HAO1 SEPHS2 SEPHS1 AASS

5.21e-05861586GO:0008652
GeneOntologyBiologicalProcessamino acid metabolic process

SDSL CAD HAO1 GGT5 SEPHS2 SEPHS1 AASS ACMSD IL4I1 VARS1 ADSS1

5.23e-0533215811GO:0006520
GeneOntologyBiologicalProcessselenocysteine biosynthetic process

SEPHS2 SEPHS1

5.83e-0521582GO:0016260
GeneOntologyBiologicalProcessproteinogenic amino acid metabolic process

SDSL CAD HAO1 SEPHS2 SEPHS1 AASS IL4I1 ADSS1

9.22e-051851588GO:0170039
GeneOntologyBiologicalProcessimmune effector process

GPI TRPM4 IGHV3-35 SEMA7A IGHV1-38-4 EVPL CFP KLK3 CFI ITGAL BCR PTK2B PTX3 PRG2 C1R IL4I1 GPRC5B IL9R

1.07e-0485915818GO:0002252
GeneOntologyBiologicalProcessalpha-amino acid metabolic process

SDSL CAD HAO1 SEPHS2 SEPHS1 AASS ACMSD IL4I1 ADSS1

1.41e-042511589GO:1901605
DomainCadherin_C

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.27e-124215410IPR032455
DomainCadherin_C_2

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.27e-124215410PF16492
DomainCadherin_2

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.31e-106515410PF08266
DomainCadherin_N

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.31e-106515410IPR013164
DomainCadherin_CS

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

2.30e-0810915410IPR020894
DomainCADHERIN_1

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.25e-0811315410PS00232
DomainCadherin

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.25e-0811315410PF00028
DomainCADHERIN_2

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.54e-0811415410PS50268
Domain-

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.54e-08114154102.60.40.60
DomainCA

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.85e-0811515410SM00112
DomainCadherin-like

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

4.18e-0811615410IPR015919
DomainCadherin

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

4.93e-0811815410IPR002126
DomainSPS/SelD

SEPHS2 SEPHS1

6.75e-0521542IPR004536
Domain-

SEPHS2 SEPHS1

2.02e-04315423.90.650.10
DomainBNR_2

NEU4 NEU3

4.01e-0441542PF13088
Domain-

SEPHS2 SEPHS1

4.01e-04415423.30.1330.10
DomainSialidase_fam

NEU4 NEU3

4.01e-0441542IPR026856
DomainAIRS_C

SEPHS2 SEPHS1

4.01e-0441542PF02769
DomainAIRS

SEPHS2 SEPHS1

4.01e-0441542PF00586
DomainPurM-like_N

SEPHS2 SEPHS1

4.01e-0441542IPR016188
DomainAIR_synth_C_dom

SEPHS2 SEPHS1

4.01e-0441542IPR010918
Domain-

SEMA6B DYNC2I2 SEMA7A APAF1 LRRK2 EML5 RPTOR DNAI2 HERC1 PLXNB3

4.52e-04333154102.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA6B DYNC2I2 SEMA7A APAF1 LRRK2 EML5 RPTOR DNAI2 HERC1 PLXNB3

4.73e-0433515410IPR015943
DomainSET

KMT2B PRDM7 PRDM9 PRDM11

5.54e-04461544SM00317
DomainSRCR

CFI MSR1 LOXL4

6.56e-04211543PF00530
Domain-

NEU4 NEU3

6.65e-04515422.120.10.10
DomainSET_dom

KMT2B PRDM7 PRDM9 PRDM11

7.62e-04501544IPR001214
DomainSET

KMT2B PRDM7 PRDM9 PRDM11

7.62e-04501544PS50280
DomainPEROXIDASE_1

PXDN PXDNL

9.91e-0461542PS00435
DomainIg_I-set

SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6

1.02e-031901547IPR013098
DomainI-set

SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6

1.02e-031901547PF07679
Domain-

CFI MSR1 LOXL4

1.11e-032515433.10.250.10
DomainSR

CFI MSR1 LOXL4

1.11e-03251543SM00202
DomainSRCR-like_dom

CFI MSR1 LOXL4

1.24e-03261543IPR017448
DomainSRCR_1

CFI MSR1 LOXL4

1.24e-03261543PS00420
DomainSRCR_2

CFI MSR1 LOXL4

1.24e-03261543PS50287
DomainKOW

GPKOW SUPT5H

1.38e-0371542SM00739
DomainSRCR

CFI MSR1 LOXL4

1.39e-03271543IPR001190
DomainTRYPSIN_HIS

PRSS57 ACR KLK3 CFI C1R

1.63e-031031545IPR018114
DomainFN3_dom

FLNC COL12A1 SPEG OBSCN OBSL1 IGDCC3 IL9R

1.76e-032091547IPR003961
DomainSSXRD

PRDM7 PRDM9

1.83e-0381542PF09514
DomainSSXRD_motif

PRDM7 PRDM9

1.83e-0381542IPR019041
DomainTRYPSIN_SER

PRSS57 ACR KLK3 CFI C1R

1.85e-031061545PS00135
DomainTRYPSIN_HIS

PRSS57 ACR KLK3 CFI C1R

1.93e-031071545PS00134
DomainSemap_dom

SEMA6B SEMA7A PLXNB3

2.09e-03311543IPR001627
DomainSEMA

SEMA6B SEMA7A PLXNB3

2.09e-03311543PS51004
DomainSema

SEMA6B SEMA7A PLXNB3

2.09e-03311543SM00630
DomainSema

SEMA6B SEMA7A PLXNB3

2.09e-03311543PF01403
DomainPlexin_repeat

SEMA6B SEMA7A PLXNB3

2.29e-03321543IPR002165
DomainPSI

SEMA6B SEMA7A PLXNB3

2.29e-03321543PF01437
DomainSialidases

NEU4 NEU3

2.34e-0391542IPR011040
DomainPeptidase_S1A

PRSS57 ACR KLK3 CFI C1R

2.45e-031131545IPR001314
DomainTRYPSIN_DOM

PRSS57 ACR KLK3 CFI C1R

2.65e-031151545PS50240
DomainTryp_SPc

PRSS57 ACR KLK3 CFI C1R

2.85e-031171545SM00020
DomainIG_FLMN

FLNA FLNC

2.91e-03101542SM00557
DomainAn_peroxidase

PXDN PXDNL

2.91e-03101542PF03098
DomainHaem_peroxidase_animal

PXDN PXDNL

2.91e-03101542IPR019791
DomainHaem_peroxidase

PXDN PXDNL

2.91e-03101542IPR010255
DomainPEROXIDASE_3

PXDN PXDNL

2.91e-03101542PS50292
Domain-

PXDN PXDNL

2.91e-031015421.10.640.10
DomainTrypsin_dom

PRSS57 ACR KLK3 CFI C1R

3.30e-031211545IPR001254
DomainTrypsin

PRSS57 ACR KLK3 CFI C1R

3.30e-031211545PF00089
Domain-

FLNA FLNC COL12A1 SEMA7A SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6 PLXNB3 IL9R

3.39e-03663154132.60.40.10
DomainIGc2

SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6

3.40e-032351547SM00408
DomainIg_sub2

SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6

3.40e-032351547IPR003598
DomainPeptidase_S1_PA

PRSS57 ACR KLK3 CFI C1R

3.54e-031231545IPR009003
DomainFilamin

FLNA FLNC

3.54e-03111542PF00630
DomainKRAB_RELATED

PRDM7 PRDM9

3.54e-03111542PS50806
DomainKOW

GPKOW SUPT5H

3.54e-03111542IPR005824
DomainZF_CXXC

KMT2B TET1

3.54e-03111542PS51058
DomainKOW

GPKOW SUPT5H

3.54e-03111542PF00467
DomainFILAMIN_REPEAT

FLNA FLNC

3.54e-03111542PS50194
DomainFilamin/ABP280_rpt

FLNA FLNC

3.54e-03111542IPR001298
DomainFilamin/ABP280_repeat-like

FLNA FLNC

3.54e-03111542IPR017868
DomainZnf_CXXC

KMT2B TET1

3.54e-03111542IPR002857
DomainIntegrin_alpha

ITGA7 ITGAL

3.54e-03111542PF00357
Domainzf-CXXC

KMT2B TET1

3.54e-03111542PF02008
DomainAmidohydro-rel

CAD ACMSD

3.54e-03111542IPR006680
DomainVWC

FCGBP PXDN PXDNL

3.75e-03381543SM00214
DomainFN3

FLNC COL12A1 SPEG OBSCN OBSL1 IGDCC3

4.37e-031851546SM00060
DomainSET

KMT2B PRDM9 PRDM11

4.66e-03411543PF00856
DomainKrueppel-associated_box-rel

PRDM7 PRDM9

4.96e-03131542IPR003655
DomainVWF_dom

FCGBP PXDN PXDNL

4.99e-03421543IPR001007
DomainPSI

SEMA6B SEMA7A PLXNB3

5.68e-03441543IPR016201
DomainIg-like_fold

FLNA FLNC COL12A1 SEMA7A SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6 PLXNB3 IL9R

5.72e-0370615413IPR013783
DomainFN3

COL12A1 SPEG OBSCN OBSL1 IGDCC3 IL9R

6.20e-031991546PS50853
DomainPSI

SEMA6B SEMA7A PLXNB3

6.44e-03461543SM00423
DomainTRYPSIN_SER

ACR KLK3 CFI C1R

6.56e-03901544IPR033116
DomainWD40

DYNC2I2 APAF1 LRRK2 EML5 RPTOR DNAI2 HERC1

6.89e-032681547SM00320
DomainWD40_repeat

DYNC2I2 APAF1 LRRK2 EML5 RPTOR DNAI2 HERC1

7.45e-032721547IPR001680
DomainIntegrin_alpha_C_CS

ITGA7 ITGAL

7.51e-03161542IPR018184
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

6.44e-19201621011322959
Pubmed

Protocadherins.

PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB3 PCDHB16

7.00e-1413162712231349
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.30e-13571621032633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.56e-13581621030377227
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

8.37e-13681621011230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.52e-12721621010380929
Pubmed

Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.

PCDHB15 PCDHB12 PCDHB11 PCDHB8 PCDHB7 PCDHB3

1.92e-1210162622969705
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

2.02e-12741621010817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.05e-12771621010835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

4.52e-12801621010716726
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6B SDSL TRPM4 FLNA FLNC MAN2A2 KMT2B ZNF628 SEMA7A SPEG OBSCN TBC1D25 BCR ABCA7 KIFC2 SEPHS2 INTS5 RPTOR TMEM268 USP40 HERC1 HR

1.08e-0811051622235748872
Pubmed

Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.

PCDHB15 PCDHB12 PCDHB11 PCDHB8 PCDHB3

1.22e-0817162518279309
Pubmed

A unique role of cohesin-SA1 in gene regulation and development.

PCDHB15 PCDHB14 PCDHB8 PCDHB16

7.90e-0716162422415368
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MTMR12 CEP85 TTC28 OBSL1 RAD54L2 WLS BCR MOGS SUPT5H CTR9 CHTF18 ANAPC2 HSD17B12 HR

2.41e-066501621438777146
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

FLNA FLNC MTMR12 CEP85 MLEC DYNC2I2 PDHB OBSL1 EVPL BCR NUP205 PTPN14 SUPT5H CTR9 ATP6AP2 NID1 VARS1

3.36e-069741621728675297
Pubmed

The yin-yang of PR-domain family genes in tumorigenesis.

PRDM7 PRDM9 PRDM11

3.42e-067162310668202
Pubmed

Identification of novel cadherins expressed in human melanoma cells.

PCDHB14 PCDHB11 PCDHB16

3.42e-06716239182820
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CAD CEP85 TTC28 USP28 OBSL1 RAD54L2 BCR SEPHS1 PTPN14 SUPT5H CTR9 RPTOR SNX9

4.22e-065881621338580884
Pubmed

Transient expression of MIDC-8 in the normal mouse brain.

NES MSR1 CD68

5.46e-068162315755524
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

NES FLNA FLNC

5.46e-068162317145501
Pubmed

SET domains and histone methylation.

PRDM7 PRDM9 PRDM11

5.46e-068162314675547
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

FLNA FLNC KMT2B GHDC OBSCN LOXL4 CTSB HERC5

7.91e-06214162822199357
Pubmed

Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.

PCDHB15 PCDHB12 PCDHB11 PCDHB3 PCDHB16

8.42e-0659162523754746
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

FLNA GHDC OBSL1 WLS NUP205 INTS5 PXDN MOGS ATP6AP2 RPTOR ANAPC2 HSD17B12 RAB39A SNX9 KLHDC4 VARS1

9.28e-069421621631073040
Pubmed

La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).

GPI CAD EVPL HSPA13 RPTOR SNX9

1.34e-05110162625940091
Pubmed

Acute and late disease induced by murine coronavirus, strain JHM, in a series of recombinant inbred strains between BALB/cHeA and STS/A mice.

GPI ITGAL

2.16e-05216221316530
Pubmed

Presence of aberrant epididymal tubules revealing undifferentiated epithelial cells and absence of spermatozoa in a combined neuraminidase-3 and -4 deficient adult mouse model.

NEU4 NEU3

2.16e-052162230359429
Pubmed

USP40 gene knockdown disrupts glomerular permeability in zebrafish.

NES USP40

2.16e-052162228148530
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

2.16e-05216227689010
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

2.16e-052162210679933
Pubmed

The function of Wls in ovarian development.

AMHR2 WLS

2.16e-052162233359762
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

2.16e-052162224469451
Pubmed

Evidence for mitochondrial localization of a novel human sialidase (NEU4).

NEU4 NEU3

2.16e-052162215847605
Pubmed

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.

FLNC OBSCN

2.16e-052162229073160
Pubmed

Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.

SPEG OBSCN

2.16e-052162215185077
Pubmed

Selenophosphate synthetase genes from lung adenocarcinoma cells: Sps1 for recycling L-selenocysteine and Sps2 for selenite assimilation.

SEPHS2 SEPHS1

2.16e-052162215534230
Pubmed

Integrin-mediated cell migration is blocked by inhibitors of human neuraminidase.

NEU4 NEU3

2.16e-052162227344026
Pubmed

ATP6AP2/(pro)renin receptor contributes to glucose metabolism via stabilizing the pyruvate dehydrogenase E1 β subunit.

PDHB ATP6AP2

2.16e-052162225720494
Pubmed

p210BCR/ABL-induced alteration of pre-mRNA splicing in primary human CD34+ hematopoietic progenitor cells.

BCR PTK2B

2.16e-052162214961028
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

GPI FLNA APAF1 LRRK2 EVPL CFI BCR ADCY1 MELTF FCGBP EML5 MOGS ATP6AP2 NID1 SNX9 GPRC5B

2.34e-0510161621619056867
Pubmed

Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf-1 and Caspase-9 apoptosome expression.

GPI APAF1

6.45e-053162214566819
Pubmed

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

FLNA FLNC

6.45e-053162211038172
Pubmed

The Janus-like role of neuraminidase isoenzymes in inflammation.

NEU4 NEU3

6.45e-053162235363389
Pubmed

Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides.

NEU4 NEU3

6.45e-053162228442549
Pubmed

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

OBSCN OBSL1

6.45e-053162220133654
Pubmed

Differential expression of endogenous sialidases of human monocytes during cellular differentiation into macrophages.

NEU4 NEU3

6.45e-053162215885103
Pubmed

Precise mapping of the gene for Ly-21.2 on the 7th chromosome.

GPI ITGAL

6.45e-05316227161508
Pubmed

Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.

FLNA FLNC

6.45e-053162211102480
Pubmed

Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.

FLNA FLNC

6.45e-053162217825253
Pubmed

Effects of PPM1K rs1440581 and rs7678928 on serum branched-chain amino acid levels and risk of cardiovascular disease.

LRRK2 VARS1

6.45e-053162234382495
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNC

6.45e-053162212393796
Pubmed

Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate.

ITGAL PTK2B

6.45e-053162220805505
Pubmed

Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

FLNA FLNC

6.45e-05316229412467
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNC

6.45e-053162211153914
Pubmed

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

OBSCN OBSL1

6.45e-053162227989621
Pubmed

Analysis of Novel Interactions between Components of the Selenocysteine Biosynthesis Pathway, SEPHS1, SEPHS2, SEPSECS, and SECp43.

SEPHS2 SEPHS1

6.45e-053162228414460
Pubmed

Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.

KMT2B TET1

6.45e-053162231844322
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNC

6.45e-053162211252955
Pubmed

The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.

FLNA FLNC

6.45e-053162212704190
Pubmed

Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice.

TRPM4 ADCY1

6.45e-053162224972051
Pubmed

Human sialidase as a cancer marker.

NEU4 NEU3

6.45e-053162218651674
Pubmed

The relationship among integrin alpha 7, CD133 and Nestin as well as their correlation with clinicopathological features and prognosis in astrocytoma patients.

NES ITGA7

6.45e-053162235430343
Pubmed

Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.

OBSCN OBSL1

6.45e-053162231098411
Pubmed

Apaf-1 deficiency and neural tube closure defects are found in fog mice.

APAF1 ABCA7

6.45e-053162211504943
Pubmed

Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.

FLNC ANK3

6.45e-053162221223964
Pubmed

LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.

ITGAL PTK2B

6.45e-053162228699640
Pubmed

Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin.

OBSCN OBSL1

6.45e-053162220489725
Pubmed

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

PCDHB14 PCDHB8 PCDHB16

9.10e-0519162323920377
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD CEP85 ANK3 MLEC TTC28 CLIP2 PDHB USP28 OBSL1 DNAAF9 RAD54L2 HSPA13 SUPT5H CTR9 CTSB VARS1 PLXNB3

1.11e-0412851621735914814
Pubmed

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression.

AGO2 LRRK2

1.29e-044162220671708
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNA FLNC

1.29e-044162211739414
Pubmed

Monosodium urate activates Src/Pyk2/PI3 kinase and cathepsin dependent unconventional protein secretion from human primary macrophages.

PTK2B CTSB

1.29e-044162223292187
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNA FLNC

1.29e-044162222802962
Pubmed

SSAO/VAP-1 protein expression during mouse embryonic development.

NES AOC3

1.29e-044162218729210
Pubmed

Chromosomal localization of the ankyrinG gene (ANK3/Ank3) to human 10q21 and mouse 10.

ANK3 BCR

1.29e-04416227665168
Pubmed

MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.

AMHR2 KMT2B

1.29e-044162220808952
Pubmed

The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.

FLNA FLNC

1.29e-044162220554076
Pubmed

LINC00467 enhances head and neck squamous cell carcinoma progression and the epithelial-mesenchymal transition process via miR-299-5p/ubiquitin specific protease-48 axis.

AGO2 USP48

1.29e-044162232159247
Pubmed

Developmental change of sialidase neu4 expression in murine brain and its involvement in the regulation of neuronal cell differentiation.

NEU4 NEU3

1.29e-044162219506080
Pubmed

Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.

PRDM7 PRDM9

1.29e-044162218231586
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

SEMA6B FLNA FLNC MAN2A2 MLEC SEMA7A P3H3 PDHB SPEG WLS PTPN14 MOGS HSD17B12 LOXL4 C1R NID1 CTSB VARS1

1.55e-0414511621830550785
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

GPI COL12A1 CFI PXDN PTX3 NID1 CTSB

1.72e-04248162724006456
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD NES MTMR12 CARMIL2 TTC28 KIF26B BCR PTK2B PTPN14 MYLK3 AASS RPTOR TET1

2.11e-048611621336931259
Pubmed

CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells.

USP28 TET1

2.14e-045162230635654
Pubmed

A critical function of the pial basement membrane in cortical histogenesis.

NES NID1

2.14e-045162212122064
Pubmed

Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.

ANK3 TET1

2.14e-045162218163421
Pubmed

Adult Apaf-1-deficient mice exhibit male infertility.

NES APAF1

2.14e-045162210656767
Pubmed

Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.

FLNA FLNC

2.14e-045162212006559
Pubmed

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

FLNA FLNC

2.14e-045162217360453
Pubmed

Apoptosome inactivation rescues proneural and neural cells from neurodegeneration.

NES APAF1

2.14e-045162215257302
Pubmed

HIV infection of T cells: actin-in and actin-out.

FLNA FLNC

2.14e-045162219366992
Pubmed

Clearance of apoptotic cells is not impaired in mouse embryos deficient in class A scavenger receptor types I and II (CD204).

MSR1 CD68

2.14e-045162215580571
Pubmed

The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects.

HERC1 HERC5

2.14e-045162215676274
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

FLNA CAD CEP85 AGO2 KMT2B ANK3 TTC28 PTPN14 TET1 SNX9

2.69e-045491621038280479
Pubmed

Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.

PCDHB8 PCDHB3 PCDHB16

2.98e-0428162333523829
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

PDHB GPKOW MOGS SUPT5H CTR9 RPTOR ANAPC2 RAB39A SNX9 VARS1

3.15e-045601621035241646
Pubmed

Fine genetic map of mouse chromosome 10 around the polycystic kidney disease gene, jcpk, and ankyrin 3.

ANK3 BCR

3.20e-04616228812475
Pubmed

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription.

AGO2 CTR9

3.20e-046162226902284
Pubmed

Genome-wide association analysis identifies six new loci associated with forced vital capacity.

PRDM11 HSD17B12

3.20e-046162224929828
Pubmed

Glycogen synthase: a putative locus for diet-induced hyperglycemia.

GPI KLK3

3.20e-04616228040269
InteractionPCDHB3 interactions

SEMA6B TEPSIN PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16 ATP6AP2

1.55e-061411569int:PCDHB3
InteractionTOP3B interactions

GPI SEMA6B SDSL TRPM4 FLNA FLNC CAD AGO2 MAN2A2 KMT2B ZNF628 SEMA7A SPEG OBSCN TBC1D25 BCR ABCA7 KIFC2 SEPHS2 INTS5 MOGS ATP6AP2 RPTOR TMEM268 USP40 HSD17B12 HERC1 HR

7.83e-06147015628int:TOP3B
InteractionC1QB interactions

SEMA6B COL12A1 MAN2A2 P3H3 OBSL1 PTX3 C1R

8.47e-06941567int:C1QB
InteractionPCDHB10 interactions

PCDHB10 PCDHB3 PCDHB16

1.56e-0571563int:PCDHB10
Cytoband5q31

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.23e-11115162105q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

1.24e-0729816210chr5q31
Cytoband15q22.3-q23

SEMA7A IGDCC3

7.39e-054162215q22.3-q23
CytobandEnsembl 112 genes in cytogenetic band chr17q25

TEPSIN EVPL GRIN2C ZACN RPTOR DNAH17 DNAI2

1.18e-043071627chr17q25
Cytoband12q13

AMHR2 P3H3 ITGA7 HSD17B6

1.21e-0471162412q13
CytobandEnsembl 112 genes in cytogenetic band chr19q13

GPI TRPM4 KMT2B ZNF628 HIF3A FBXO17 KLK3 ZNF446 FCGBP DMKN SUPT5H SIGLEC6 IL4I1

3.36e-04119216213chr19q13
Cytoband17q25

EVPL GRIN2C DNAI2

3.59e-0439162317q25
CytobandXq28

FLNA PNMA6E TMEM185A PLXNB3 IL9R

4.21e-041761625Xq28
Cytoband17q25.3

TEPSIN ZACN RPTOR DNAH17

4.67e-04101162417q25.3
Cytoband19q13.1

GPI KMT2B FCGBP

9.89e-0455162319q13.1
CytobandEnsembl 112 genes in cytogenetic band chrXq28

FLNA PNMA6E TMEM185A PLXNB3 IL9R

9.94e-042131625chrXq28
Cytoband10q21

ANK3 TET1

1.44e-0316162210q21
Cytoband2q35

SPEG OBSL1 RESP18

2.80e-037916232q35
GeneFamilyClustered protocadherins

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16

3.62e-12641061020
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

SPEG OBSCN OBSL1 IGDCC3 PXDN PXDNL SIGLEC6

4.54e-051611067593
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM7 PRDM9 PRDM11

1.25e-041710631197
GeneFamilyComplement system|Sushi domain containing

CFP CFI C1R

1.21e-03361063492
GeneFamilyZinc fingers CXXC-type

KMT2B TET1

2.16e-03121062136
GeneFamilyUbiquitin specific peptidases

USP28 USP40 USP48

4.33e-03561063366
GeneFamilyDyneins, axonemal

DNAH17 DNAI2

4.37e-03171062536
GeneFamilyWD repeat domain containing

DYNC2I2 APAF1 EML5 RPTOR DNAI2 HERC1

4.46e-032621066362
GeneFamilyCD molecules|Integrin alpha subunits

ITGA7 ITGAL

4.90e-031810621160
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA6B SEMA7A

6.04e-03201062736
CoexpressionLIU_PROSTATE_CANCER_DN

FLNA FLNC TTC28 P3H3 SPEG TMEM185A FHOD3 DNAAF9 FBXO17 MELTF FCGBP DMKN AOC3 C1R NID1 CTSB

5.98e-0849315916M19391
CoexpressionMIKKELSEN_ES_HCP_WITH_H3K27ME3

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB7 PCDHB16

1.98e-07421596MM1275
CoexpressionPRC2_EED_DN.V1_DN

TRPM4 CAD FBXO17 RAD54L2 XRCC3 ZNF446 PTK2B VARS1 PLXNB3

2.90e-061931599M2734
CoexpressionMIKKELSEN_ES_HCP_WITH_H3K27ME3

PCDHB15 PCDHB14 PCDHB12 PCDHB7 PCDHB16

4.84e-06411595M2000
CoexpressionCAIRO_LIVER_DEVELOPMENT_DN

CFP TST ABCA7 ABCC6 PRG2 LPIN2 CD68 NID1 HERC1

1.01e-052251599M6175
CoexpressionBERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN

FLNA FLNC TTC28 SPEG OBSL1 DNAAF9 PTPN14 AOC3

1.48e-051801598M10605
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

FLNA TTC28 P3H3 SPEG OBSL1 PTGR2 CFP WLS ITGAL PCDHB16 GGT5 MSR1 PTK2B MELTF ATP6AP2 CHTF18 SIGLEC6 CD68 NID1 CTSB PLXNB3 ADSS1

1.58e-05131615922MM1052
CoexpressionCAIRO_LIVER_DEVELOPMENT_DN

CFP TST ABCA7 ABCC6 PRG2 LPIN2 CD68 NID1 HERC1

1.63e-052391599MM1274
CoexpressionHAY_BONE_MARROW_STROMAL

COL12A1 PCDHB15 PCDHB14 PCDHB12 PCDHB10 PCDHB7 FBXO17 CFI PCDHB16 GGT5 TMEM132C PTX3 C1R NID1 FKBP7 GPRC5B

1.85e-0576715916M39209
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

FLNA TTC28 P3H3 SPEG OBSL1 PTGR2 CFP WLS ITGAL PCDHB16 GGT5 MSR1 PTK2B MELTF ATP6AP2 CHTF18 CD68 NID1 CTSB PLXNB3 ADSS1

2.12e-05124215921M1920
CoexpressionMIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9

2.24e-05931596MM1266
CoexpressionGSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_DN

HAO1 MSR1 FCGBP HSD17B6 DNAH17 PLXNB3 GPRC5B HR

2.84e-051971598M8431
CoexpressionGSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_UP

COL12A1 MYLK3 EML5 SUPT5H CD68 LOXL4 IL4I1 BANK1

3.17e-052001598M8488
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_180MIN_DN

NES DYNC2I2 WLS MSR1 ATP6AP2 RPTOR AOC3 IL9R

3.17e-052001598M6634
CoexpressionLIAN_LIPA_TARGETS_3M

SEMA7A CFP MSR1 CD68 CTSB

5.11e-05661595M16088
CoexpressionGAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS

JCAD NES FLNA COL12A1 OBSCN ITGA7 GGT5 PXDN TET1 AOC3 C1R NID1

6.33e-0550515912M39167
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

FLNA FLNC KMT2B MLEC OBSL1 TMEM185A TBC1D25 PXDN MOGS CTR9 HSD17B12 NID1 VARS1 GPRC5B

7.36e-0568115914M5314
CoexpressionLIAN_LIPA_TARGETS_3M

SEMA7A CFP MSR1 CD68 CTSB

8.31e-05731595MM1020
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_3_CELL

FLNC ANK3 P3H3 KIF26B CFI DMKN PTX3

9.63e-051741597M45676
CoexpressionLIAN_LIPA_TARGETS_6M

SEMA7A CFP MSR1 CD68 CTSB

1.44e-04821595M4345
CoexpressionAtlaskidney_P1_CapMes_Crym_top-relative-expression-ranked_1000

TRPM4 COL12A1 AGO2 ANK3 MLEC TTC28 KIF26B PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16 SEPHS1 PTPN14 LPIN2 FKBP7

1.10e-0663315718gudmap_kidney_P1_CapMes_Crym_1000
CoexpressionAtlaskidney_P0_CapMes_Crym_top-relative-expression-ranked_1000

TRPM4 AGO2 ANK3 MLEC TTC28 KIF26B PCDHB9 PCDHB8 PCDHB3 TMEM185A PCDHB16 SEPHS1 PTPN14 LPIN2 CD68 FKBP7

2.18e-0563915716gudmap_kidney_P0_CapMes_Crym_1000
CoexpressionAtlasPP_RBC_top-relative-expression-ranked_2500_k-means-cluster#3

PCDHB15 PCDHB14 PCDHB12 PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB3

2.35e-051581578PP_RBC_2500_K3
CoexpressionAtlaskidney_P1_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000

TRPM4 AGO2 TTC28 KIF26B PCDHB11 PCDHB10 PCDHB9 PCDHB8 PCDHB7 PCDHB3 PCDHB16 SEPHS1

4.54e-0540115712gudmap_kidney_P1_CapMes_Crym_k1_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#3

MAN2A2 ANK3 TTC28 P3H3 KIF26B IGDCC3 NEU3 CFP HIF3A ALS2CL MSR1 PRDM11 NID1 FKBP7

8.44e-0556715714Facebase_RNAseq_e10.5_Olfactory Pit_2500_K3
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 CARMIL2 PCDHB15 PCDHB14 PCDHB10 PCDHB7 MBLAC1 MYLK3 CHTF18

1.24e-08170161912203d4410f38cc933d9f160b5fb76828df94119
ToppCellfacs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 CARMIL2 PCDHB15 PCDHB14 PCDHB10 PCDHB7 MBLAC1 MYLK3 CHTF18

1.24e-081701619f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

JCAD PCDHB15 HIF3A PTPN14 TET1 AOC3 NID1 GPRC5B

1.69e-071661618f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NES FLNA FLNC KIF26B SPEG ITGA7 AOC3 HR

4.36e-071881618c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellNS-critical-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SEMA6B SDSL FLNA AOAH MSR1 CD68 CTSB IL4I1

4.72e-0719016184fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

JCAD FLNC GGT5 PTPN14 PXDN PTX3 NID1 GPRC5B

5.31e-07193161868eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 AOAH PCDHB11 CFP ABCC6 CD68 ADSS1

2.11e-06162161771d7849108a1b59beff40e46000172c45a2f5439
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

JCAD PCDHB15 HIF3A PTPN14 TET1 NID1 GPRC5B

2.58e-0616716175c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA AOAH CFP ITGAL MSR1 CD68 ADSS1

2.79e-061691617907e4c7d0df6dd46664d69834251aebca8e1dd1e
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FLNC COL12A1 EVPL CFI ALS2CL PXDN LOXL4

3.14e-0617216170be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellILEUM-inflamed-(4)_Mast|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SDSL AMHR2 PRSS57 EVPL PRG2 SIGLEC6 IL9R

3.14e-061721617be82f749f4b1049ae8832facc052082cf5463c11
ToppCelldroplet-Fat-Scat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFP MSR1 DMKN PTX3 CD68 CTSB ADSS1

3.14e-0617216178a4a5ad65eec92ce4fa45c5aa01c28666307455b
ToppCellILEUM-inflamed-(4)_Mast_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SDSL AMHR2 PRSS57 EVPL PRG2 SIGLEC6 IL9R

3.14e-0617216177185b28282412f3a464b2a8ad5605475a1a31358
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFP ITGAL MSR1 TMEM268 CD68 CTSB BANK1

3.52e-0617516171973fff0d7e1a94b31f461a39b91cc7984ebd8f1
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFP ITGAL MSR1 TMEM268 CD68 CTSB BANK1

3.65e-0617616171e430dffddd315d9a1cb4bd7fef5077656351c65
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SDSL MSR1 FCGBP ATP6AP2 CD68 CTSB IL4I1

3.94e-061781617e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOAH CFP ITGAL MSR1 SIGLEC6 CD68 RAB39A

4.08e-061791617330c1326ba93bb8f32559ee1cc40e357cc44ad8d
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOAH CFP ITGAL MSR1 SIGLEC6 CD68 RAB39A

4.08e-061791617dc03b9045510eb1bb934329646bb92dd06890ce9
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

NES COL12A1 PCDHB12 OBSCN ITGA7 AOC3 NID1

4.39e-061811617f74941e49950027360d71ea3b205fc20c6929766
ToppCellLPS-antiTNF-Myeloid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOAH CFP ITGAL MSR1 PTK2B PTX3 CD68

5.26e-061861617839c6da5244f469461b2e5563e36162b2911cd01
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA COL12A1 PCDHB7 GGT5 AOC3 C1R NID1

5.84e-0618916179e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6B FLNC MTMR12 BCR PTPN14 PTX3 GPRC5B

6.04e-06190161726e2237f65cb43723c5da853831b40df2982d6e4
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6B FLNC MTMR12 BCR PTPN14 PTX3 GPRC5B

6.04e-061901617a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA6B FLNC MTMR12 BCR PTPN14 PTX3 GPRC5B

6.04e-0619016170bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B FLNC MTMR12 BCR PTPN14 PTX3 GPRC5B

6.25e-06191161748823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B FLNC MTMR12 BCR PTPN14 PTX3 GPRC5B

6.25e-0619116170eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

COL12A1 WLS PXDN HSD17B6 AOC3 C1R NID1

6.69e-061931617084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCelldistal-3-Hematologic-Basophil/Mast_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AMHR2 MAN2A2 SEMA7A EVPL PRDM11 PRG2 SIGLEC6

6.69e-06193161723c6c798525dad43eff792727902ea562bf373be
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TTC28 HIF3A TMEM132C AASS C1R NID1 HR

7.16e-061951617ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P3H3 GGT5 PXDN PTX3 C1R NID1 FKBP7

7.16e-06195161778cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SDSL MSR1 FCGBP ATP6AP2 CD68 CTSB IL4I1

7.40e-061961617bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNA FLNC COL12A1 SPEG ITGA7 AOC3 NID1

7.40e-06196161770b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MSR1 FCGBP CD68 RAB39A CTSB IL4I1 TSGA10IP

7.40e-061961617b15812354128c12a588d79ef449d787e74835f3b
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNA FLNC COL12A1 SPEG ITGA7 AOC3 NID1

7.40e-061961617ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NES FLNA ANKRD10 ITGA7 PCDHB16 PTX3 C1R

7.40e-061961617b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SDSL MSR1 FCGBP ATP6AP2 CD68 CTSB IL4I1

7.40e-061961617072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SDSL MSR1 FCGBP ATP6AP2 CD68 CTSB IL4I1

7.65e-06197161772775eb6c24cfb956436642ac9cd6e4d5c01ea5f
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA6B NEU4 CFP MSR1 ZACN CTSB SNX9

7.65e-061971617e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL12A1 OBSL1 HIF3A TMEM132C PXDN C1R NID1

7.65e-0619716173bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL12A1 OBSL1 HIF3A TMEM132C PXDN C1R NID1

7.65e-06197161717344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SDSL MSR1 FCGBP ATP6AP2 CD68 CTSB IL4I1

7.65e-061971617075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL12A1 OBSL1 HIF3A TMEM132C PXDN C1R NID1

7.65e-0619716175b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNA FLNC SPEG HIF3A ITGA7 AOC3 NID1

7.65e-061971617ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNA FLNC SPEG FHOD3 HIF3A ITGA7 NID1

7.91e-061981617c12e7511628db819a52959bb68580e27c00c2e41
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNA FLNC SPEG FHOD3 HIF3A ITGA7 WLS

7.91e-06198161722e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SDSL MSR1 FCGBP ATP6AP2 CD68 CTSB IL4I1

7.91e-0619816179a89083280d4253f282300cdf1e61746d1f32407
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

JCAD COL12A1 GGT5 TMEM132C C1R NID1 FKBP7

8.17e-06199161712133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA6B SDSL AOAH CFP MSR1 CD68 CTSB

8.17e-0619916179df2c79904dacf029ec9df1f1cde72d871189a82
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AOAH ITGAL MSR1 RAB39A CTSB IL4I1 HERC5

8.17e-061991617841338719d042247966867ac608146395eb8c4d9
ToppCellILEUM-non-inflamed-(8)_Smooth_muscle_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLNA COL12A1 WLS DMKN HSD17B6 AOC3 C1R

8.17e-0619916173368c0a90a47c4dcdfe70be3192550df0744e508
ToppCellfacs-Lung-EPCAM-24m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACR RBP3 FHOD3 CFI RESP18

8.30e-0676161598271aadf026a01bf933f8279d11a0413e47d549
ToppCellTracheal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SDSL AMHR2 NEU4 SEMA7A PRG2 SIGLEC6 IL9R

8.45e-0620016171c58860932ed47263a5a537a64f0343201463c21
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PCDHB3 ITGA7 ZNF469 SLC25A43 CD68 IL4I1 ADSS1

8.45e-062001617be1abe5bb1ce4e7dfec63af4ed0fc5b96bf77866
ToppCellTracheal-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SDSL AMHR2 NEU4 SEMA7A PRG2 SIGLEC6 IL9R

8.45e-062001617c3511607692e05f44538a376253673dd18f77908
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACR RBP3 FHOD3 CFI RESP18

8.85e-06771615557f7518e9a89d99f3f2474720deb9cde10e1054
ToppCell(61)_LYVE1_Macrophage|World / shred on Cell_type and subtype

CFP KLK3 WLS MSR1 CD68 NID1 CTSB

1.02e-052061617711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCell(40)_Monocyte|World / shred on Cell_type and subtype

CFP ITGA7 KLK3 WLS MSR1 PTX3 CD68

1.02e-052061617d78a70f951265ef6df8f64404107be4f53e75d28
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACR RBP3 FHOD3 CFI RESP18

1.07e-058016156720438bf51831e98402a700dfc25bd57e0c6798
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOAH CFP ITGAL MSR1 SIGLEC6 CD68

1.53e-051461616b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOAH CFP MSR1 CD68 CTSB KLHDC4

2.40e-051581616bdfa3aa1ffc025d846f14ccb3ca84d889916021f
ToppCellE18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|E18.5-samps / Age Group, Lineage, Cell class and subclass

CFP ITGAL MSR1 PTK2B CD68 KLHDC4

2.76e-05162161660d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCellE18.5-samps-Myeloid|E18.5-samps / Age Group, Lineage, Cell class and subclass

CFP ITGAL MSR1 PTK2B CD68 KLHDC4

2.76e-05162161618e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCellE18.5-samps-Myeloid-Macrophage|E18.5-samps / Age Group, Lineage, Cell class and subclass

CFP ITGAL MSR1 PTK2B CD68 KLHDC4

2.76e-0516216160970e4eda60e3f015335e2726e6d565fb2f43372
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOAH CFP MSR1 CD68 CTSB KLHDC4

2.76e-05162161616d625ac6702f79a83af444d2b3bf6759fd17cf6
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA ITGAL PTK2B CD68 ACMSD ADSS1

2.86e-05163161604152557aae230e9587fcc16cbabf1247cc5b419
ToppCellfacs-Lung-Endomucin-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA ITGAL PTK2B CD68 ACMSD ADSS1

2.86e-0516316160644eb8a66d4e944063125c423de66d2393388b1
ToppCellnormal_Lung-Epithelial_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

ANK3 LRRK2 MSR1 HSD17B6 CD68 CTSB

2.96e-051641616fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AOAH CFP MSR1 CD68 CTSB BANK1

3.06e-0516516168d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCellfacs-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA ITGAL MSR1 PTK2B CD68 ADSS1

3.06e-051651616720649f330382ea2a68c64a5344160a048afb8f1
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AOAH CFP MSR1 CD68 CTSB BANK1

3.06e-05165161617ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCellfacs-Marrow-B-cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHB9 HSPA13 SLC25A43 PRG2 ACMSD HR

3.06e-051651616361a605d8f833d9ec54b120480dce397da35f9c3
ToppCellPND01-03-samps-Myeloid|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFP ITGAL MSR1 PTK2B CD68 KLHDC4

3.16e-05166161699dc8a186ec12d3563e81fa4618a814740332c73
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA6B MSR1 CD68 RAB39A CTSB IL4I1

3.27e-0516716162dc3de562a26077cb76855b725cf278a272d3276
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGAL MSR1 PTK2B CD68 CTSB ADSS1

3.38e-05168161600cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD AMHR2 AGO2 GHDC MSR1 SLC25A43

3.38e-0516816162e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA ITGAL PTK2B CD68 CTSB ADSS1

3.38e-0516816164b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA ITGAL PTK2B CD68 CTSB ADSS1

3.38e-051681616689c41f6e9f65381570991cc311cba49a57ec955
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA ITGAL PTK2B CD68 CTSB ADSS1

3.50e-051691616ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA ITGAL PTK2B CD68 CTSB ADSS1

3.50e-051691616c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AOAH CFP ITGAL MSR1 CD68 ADSS1

3.50e-0516916167503373fd9020c923e7eb96c7695f34054438e9e
ToppCellfacs-Lung-EPCAM-24m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AOAH CFP ITGAL MSR1 CD68 ADSS1

3.50e-051691616c934cf5b6decf6eee78243ee15c2a2c71e14cf71
ToppCelldroplet-Fat-Scat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFP MSR1 DMKN PTX3 CD68 CTSB

3.62e-051701616de722bea7527d6ad11b69f8e9589638f52854beb
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEG AOAH GGT5 INTS5 AOC3 CD68

3.62e-051701616f664c7559e383b37845c123e41a3be316d869ba0
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

FLNC OBSCN FHOD3 MSR1 FCGBP CTSB

3.62e-0517016164232fe937909f93d3736988c707b8f95ce993398
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|390C / Donor, Lineage, Cell class and subclass (all cells)

DNAAF9 MSR1 CD68 CTSB CCDC17 ADSS1

3.62e-051701616439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEG AOAH GGT5 INTS5 AOC3 CD68

3.62e-0517016160272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRG2 AOC3 RESP18 IL4I1 BANK1 IL9R

3.74e-05171161620ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCelldroplet-Lung-21m-Hematologic-myeloid|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNA CFP ITGAL CD68 CTSB ADSS1

3.74e-05171161622ad6de44e1d3f72a3d78d46fd26a5743a4f84a5
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SDSL C7orf33 CD68 RAB39A CTSB IL4I1

3.74e-051711616b520d4d5620cac08315e4cbb7e796c5e9e233060
ToppCellMonocytes-IFN-activated_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CFP KLK3 MSR1 CD68 CTSB IL4I1

3.74e-051711616df1b631618839bee4a18a2ba9c730321e5015f36
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

AOAH CFP MSR1 CD68 CTSB BANK1

3.86e-0517216169a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PCDHB7 ITGA7 GGT5 HSD17B6 C1R

3.86e-051721616ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 PCDHB7 ITGA7 GGT5 HSD17B6 C1R

3.86e-0517216161ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCellfacs-BAT-Fat-18m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA CFP ITGAL MSR1 CD68 ADSS1

3.86e-05172161636fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

JCAD FLNC GGT5 PTPN14 NID1 GPRC5B

3.86e-0517216168a527dff06d841a86c7eb04a1dd9630787294da4
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AOAH CFP ITGAL MSR1 CD68 ADSS1

3.86e-051721616f557ec1b4d08b42559da02dd1f2387283c6380a2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOAH CFP ITGAL PTK2B CD68 IL9R

3.99e-0517316160a0127bcb1d7b2b6125faef576dd843055095528
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA TTC28 ITGA7 GGT5 AOC3 NID1

3.99e-0517316162acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA TTC28 ITGA7 GGT5 AOC3 NID1

3.99e-0517316162415b6ff49f334da570577d4e93484d024a3dbd5
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 KIF26B ACR PCDHB7 PCDHB3 BCR

3.99e-0517316169dc7746a84f0e268a7c061e1bbcd5e31903034dc
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

7.99e-0531532DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

7.99e-0531532DOID:0111190 (implicated_via_orthology)
DiseaseAlzheimer disease, age at onset

JCAD COL12A1 TST TMEM132C RPTOR HSD17B12 SNX9 SPPL2C BANK1

8.02e-053431539EFO_0004847, MONDO_0004975
Diseaseeosinophil percentage of leukocytes

NEU4 CEP85 KMT2B PCDHB11 HIF3A ABCA7 NUP205 GGT5 PTK2B SEPHS2 HSD17B6 ANAPC2 IL9R

1.45e-0474615313EFO_0007991
Diseasedilated cardiomyopathy

FLNC ZBTB17 FHOD3

1.46e-04201533EFO_0000407
Diseasesemaphorin-6B measurement

SEMA6B PDHB

2.64e-0451532EFO_0021885
DiseaseParatuberculosis

AOC3 C1R

3.95e-0461532C0030524
Diseasepappalysin‐1 measurement

PXDN PRG2 BANK1

4.52e-04291533EFO_0010618
DiseaseComplement deficiency disease

CFP CFI C1R

6.65e-04331533C0272242
Diseaseaxial length measurement

DYNC2I2 RBP3 MELTF ZNF469

7.01e-04771534EFO_0005318
DiseaseLiver Cirrhosis, Experimental

FLNA COL12A1 APAF1 CFP HAO1 WLS ITGAL BCR PXDN HSD17B6 CD68 NID1

7.41e-0477415312C0023893
Diseaselysine measurement

TST AASS BANK1

9.33e-04371533EFO_0005002
Diseasenephritis (implicated_via_orthology)

ITGAL PTK2B

1.17e-03101532DOID:10952 (implicated_via_orthology)
Diseasecomplement C1q tumor necrosis factor-related protein 5 measurement

APAF1 MSR1

1.42e-03111532EFO_0801494
DiseaseParkinson disease

COL12A1 LRRK2 MSR1 DNAH17 ASCL4 CTSB SPPL2C

1.48e-033211537MONDO_0005180
Diseaseleft ventricular systolic function measurement

FLNC OBSCN PXDN

1.55e-03441533EFO_0008206
Diseasedisorder of pharynx

CARMIL2 ITGAL ADSS1

1.76e-03461533MONDO_0020592
Diseasealpha fetoprotein measurement

NEU3 TET1 ACMSD CCDC17

1.85e-031001534EFO_0010583
Diseaseosteitis deformans

NUP205 SLC25A43

2.01e-03131532EFO_0004261
Diseaseintracranial aneurysm (biomarker_via_orthology)

AOC3 CTSB

2.01e-03131532DOID:10941 (biomarker_via_orthology)
DiseaseSkin Abnormalities

APAF1 ZNF469

2.01e-03131532C0037268
Diseasebody mass index, osteoarthritis

SEMA7A BANK1 GPRC5B

2.79e-03541533EFO_0004340, MONDO_0005178
DiseaseColorectal Carcinoma

FLNC CAD RBP3 OBSCN ABCC6 MYLK3 DMKN PRG2 NID1 HR

3.73e-0370215310C0009402
Diseaseresponse to platinum based chemotherapy

SDSL ADCY1

3.87e-03181532EFO_0004647
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAI2

4.31e-03191532DOID:10003 (implicated_via_orthology)
DiseaseSarcomatoid Renal Cell Carcinoma

PDHB APAF1 LRRK2 CTSB

4.51e-031281534C1266043
DiseaseChromophobe Renal Cell Carcinoma

PDHB APAF1 LRRK2 CTSB

4.51e-031281534C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

PDHB APAF1 LRRK2 CTSB

4.51e-031281534C1266044
DiseasePapillary Renal Cell Carcinoma

PDHB APAF1 LRRK2 CTSB

4.51e-031281534C1306837
DiseaseRenal Cell Carcinoma

PDHB APAF1 LRRK2 CTSB

4.51e-031281534C0007134
Diseasecitrulline measurement

KIF26B CTSB

4.77e-03201532EFO_0009777

Protein segments in the cluster

PeptideGeneStartEntry
RSQNWGHPGVRQETG

BANK1

541

Q8NDB2
GTLKWPDGRNHVGNF

ALS2CL

371

Q60I27
AQGGDQWAVPLGRHL

CCDC185

166

Q8N715
GCFPGGVHWVSVGKQ

APAF1

176

O14727
VQGSLLHVPWRGGGQ

CHTF18

201

Q8WVB6
DGGRDPGVLGQIWQL

CCDC17

256

Q96LX7
VGGKRAQLGDLPWQV

CFI

341

P05156
VVGWLGKVFLQDGPA

ANAPC2

296

Q9UJX6
FGGHPQCLVWLIQAG

ANKRD10

101

Q9NXR5
GGHAIRILGWGVENG

CTSB

276

P07858
GRDVLGHSPGKWQQA

CXorf49;

141

A8MYA2
GVRKTGQIWPNDGEG

BCR

406

P11274
VRIVGGKAAQHGAWP

ACR

41

P10323
TWLPGEGAVQNHVLA

CARMIL2

31

Q6F5E8
GQWAGVAGMINILHG

AASS

151

Q9UDR5
LGFPGVQIGTHVNEW

ACMSD

136

Q8TDX5
GQWAGVVLDDPVGKN

CLIP2

106

Q9UDT6
PAGGQAQVRALSWGI

EEF1AKMT3

121

Q96AZ1
PGTEGQGAQKWVRNI

RAD54L2

766

Q9Y4B4
TRGVNHVEGGWPKDV

DNAI2

71

Q9GZS0
PWQVFTNIHGRGGGA

C1R

476

P00736
AVWVHVRGGPGQFNL

C7orf33

46

Q8WU49
AGAPGVAQEQSWLAG

ASTL

376

Q6HA08
QGSGPDAVGRVQGWA

ABCA7

1201

Q8IZY2
GGRNKAIATPVQGVW

AGO2

421

Q9UKV8
EGGHAVVWAGQLQGK

AMHR2

211

Q16671
VNVVLIPDNGTGGSW

AOC3

286

Q16853
IQDGWEGVKSGFVPN

RAB39A

186

Q14964
GVENPHGVWAVTRGR

P3H3

651

Q8IVL6
HVENIQGAGGSPVSW

NUP205

541

Q92621
GGQPWQLIEPVDGFH

AOAH

516

P28039
GGGEAWGISVLNPNK

CD68

186

P34810
WSHNGRPVQEGEGLE

OBSL1

1206

O75147
TNHLVTVEGGWPQFG

PDHB

286

P11177
PEEGRLEVLHQGQWG

LOXL4

41

Q96JB6
VTWLKNGQVLGPGGH

IGDCC3

361

Q8IVU1
WIPEAQILGGGQVAT

MTMR12

646

Q9C0I1
GAGLPESVIWAVNAG

MLEC

41

Q14165
VGSRHVGGLQQPRDW

KIF26B

231

Q2KJY2
VARGQWPDVRGSQHG

JCAD

521

Q9P266
GGKGLVDIQPHWVSA

HERC1

3516

Q15751
TDGKVLLWQGIGVGQ

DYNC2I2

291

Q96EX3
PGTAEQGAGGWQEVR

HR

436

O43593
GLSWGPEGLIQVRGQ

PNMA6E

596

A0A0J9YXQ4
WGPQAGGTQLTIRGQ

PLXNB3

936

Q9ULL4
GGADGVPHIDTQAGW

MYLK3

76

Q32MK0
GQQGVWVFEIGSPAT

NID1

256

P14543
DNTDPHAWVVQGPGG

EVPL

441

Q92817
HAWVVQGPGGETKRA

EVPL

446

Q92817
VQKVRAWGPGLETGQ

FLNC

571

Q14315
WGSVGPARVHLVGQG

GHDC

476

Q8N2G8
PIVWGLAFQGEKGVQ

HAO1

316

Q9UJM8
WAGAPVHLGQGQFLK

NES

1591

P48681
GPQDVGNDWEVLGVH

LRRK2

101

Q5S007
GWKPGEGIGRTFNQV

GPKOW

176

Q92917
VDHQTGPIVWGEPGT

GPI

371

P06744
YGIHWVQQSPGQGLE

IGHV1-38-4

51

P0DTW3
WQDVPQRRVGSGQGG

KMT2B

336

Q9UMN6
AVRHQPGQAGGGWDE

TEPSIN

176

Q96N21
VEGQGEKNVTFWGRP

CFP

421

P27918
EPGLFGVWAHNGEVR

PCDHB10

611

Q9UN67
EPGLFGVWAHNGEVR

PCDHB15

611

Q9Y5E8
VQDWATFAVGPGHGV

NEU4

151

Q8WWR8
SAPELGLWNGVGAVV

MFSD3

246

Q96ES6
EPGLFGVWAHNGEVR

PCDHB12

611

Q9Y5F1
EFVKRPGGQHGGDWS

MOGS

171

Q13724
KAAHFGQGTGPIWLN

MSR1

401

P21757
EPGLFGVWAHNGEVR

PCDHB11

611

Q9Y5F2
VRHGTGPAGWQLVGL

GPRC5B

151

Q9NZH0
AWGQNLHGQLGVGRK

HERC5

161

Q9UII4
PIRQGHFIVWEGAPG

OBSCN

5896

Q5VST9
SGIPQAGLGVWNEAS

PRDM9

251

Q9NQV7
ALNQGQVWIGGRITG

PRG2

151

P13727
EPGLFGVWAHNGEVR

PCDHB16

611

Q9NRJ7
HGGNGWAIEKNLTPV

FBXO17

126

Q96EF6
EPGLFGVWAHNGEVR

PCDHB14

611

Q9Y5E9
EPGLFGVWAHNGEVR

PCDHB7

611

Q9Y5E2
VWTKTGGQLPVEGQH

PXDNL

451

A1KZ92
GSVVFRNGNWPIPGE

ATP6AP2

26

O75787
AHDGQDQVGVGQLWP

RESP18

76

Q5W5W9
GAAGGPATAEQGVWQ

ADCY1

151

Q08828
TQNEGHPKWFVLGVG

FKBP7

76

Q9Y680
VGDRGLWGLVNNAGI

HSD17B6

101

O14756
HVQWQPVGGATGYIL

COL12A1

1491

Q99715
DAVRGSWQGVPGHNG

DMKN

126

Q6E0U4
GVVSPVDFLQHQGWG

DNAH17

3761

Q9UFH2
AVGGKPAGWQVGGAQ

FCGBP

4626

Q9Y6R7
WGGQNIGRSPFEVKV

FLNA

556

P21333
NQKVRAWGPGLEGGV

FLNA

576

P21333
GENGIEQSWFPAVGH

CEP85

156

Q6P2H3
TTGLWPAGVQDAGVN

FHOD3

651

Q2V2M9
IGNLHLAKQEWGPGQ

CTR9

571

Q6PD62
KWPIVQAFALEGIGG

DNAAF9

181

Q5TEA3
NEAGVGPGLGEWAVV

HSD17B12

41

Q53GQ0
AQALPLGTGAQWIGV

GGT5

126

P36269
WVKARQHGPDGQGFP

ANK3

2646

Q12955
PGVSWVHPDGVGVQI

IFFO2

181

Q5TF58
LEVWATPGHGGQRDV

MBLAC1

161

A4D2B0
RLVGNGQLEIATGGW

MAN2A2

236

P49641
QAWGLEGAAGAVPQR

ASCL4

131

Q6XD76
AHQAVVVPQGGGQLW

KLHDC4

121

Q8TBB5
VVPQGGGQLWVFGGE

KLHDC4

126

Q8TBB5
AIQAGIDGGSWPLQV

HSPA13

441

P48723
NQWLGVSVRSQGPGG

ITGA7

121

Q13683
NILVNGHVDGPIWGL

EML5

1686

Q05BV3
QGWNITVDLVIGPKG

PTK2B

271

Q14289
QGGIQVAGLTHWDVP

KIFC2

556

Q96AC6
EPGLFGVWAHNGEVR

PCDHB3

611

Q9Y5E6
GNIVGWGVTEIQPHG

PTX3

361

P26022
WGVTEIQPHGGAQYV

PTX3

366

P26022
VHQAPGKGLEWVSGV

IGHV3-35

56

A0A0C4DH35
LHGPVVRQLWDGTGV

IL4I1

426

Q96RQ9
TEPGLFGVWAHNGEV

PCDHB8

611

Q9UN66
EPGLFGVWAHNGEVR

PCDHB9

611

Q9Y5E1
GPGGSRAAVLVQQWV

VARS1

86

P26640
ARQQLGAWGGVSIPT

TSGA10IP

171

Q3SY00
TNPDVGGGWLEGRNI

SNX9

31

Q9Y5X1
NEIGGLLQTRGHEWG

ADSS1

316

Q8N142
QVADAGFGGHRGWPV

TBC1D25

451

Q3MII6
HTGINRTVGWNVPVG

MELTF

131

P08582
EPRQWGVKQEVGSGG

TMEM132C

341

Q8N3T6
VGASVGTGVWARNPQ

TMEM185A

56

Q8NFB2
GGIWIDGVPIAHVGL

ABCC6

1321

O95255
AAGEWNQVGAGGEPL

HIF3A

71

Q9Y2N7
GQTQGEGDWKVPQGV

PRDM11

391

Q9NQV5
SGIPQAGLGVWNEAS

PRDM7

251

Q9NQW5
VVGGAEWHYIATQGP

PTPN14

971

Q15678
PAGSWGAQIIGGHEV

PRSS57

26

Q6UWY2
GGQTVLNPWIVLGGV

SEPHS1

161

P49903
KGWLAQGQGAHGLLI

SPPL2C

106

Q8IUH8
VHWKPEGRAGGVLGA

SIGLEC6

336

O43699
GGQHEWGELVQLDPQ

SUPT5H

531

O00267
QVGVVRGHARGPWAT

SLC25A43

41

Q8WUT9
GVAWVLAGHCQRPGL

IL9R

486

Q01113
LVGWEQQGGEGPAAL

INTS5

581

Q6P9B9
GRVLLFQEPQGGGHW

ITGAL

431

P20701
NGHGVPRPTVNGEVW

RPTOR

151

Q8N122
GVVAGLLEVGWQHVP

SDSL

181

Q96GA7
IQGSQGIGSPGEIRW

SLC6A7

201

Q99884
GQAFGAIPHQWELPG

TET1

366

Q8NFU7
WATFAVGPGHGIQLQ

NEU3

156

Q9UQ49
PGWGQELHNGQVLTV

TMEM268

31

Q5VZI3
AVDVGAGPWGNQTVV

SEMA6B

431

Q9H3T3
TGGQTVVNPWIIIGG

SEPHS2

211

Q99611
NHGEAWLGGGVVPDA

RBP3

601

P10745
EPGWAATGLRKGVQH

SPEG

1341

Q15772
SQGAASWPGAGVRVV

SPIDR

471

Q14159
AWGTLAVVAQKPGAG

PXDN

21

Q92626
GPRIFAVWKGHVGQD

SEMA7A

51

O75326
RVDGWPVGLKNVGNT

USP28

156

Q96RU2
EWLQQHGIPGLQGVD

CAD

106

P27708
VEGLQHDPGQLLGWI

ZNF446

101

Q9NWS9
ENGQWKGQAPHGPVT

ZNF469

2431

Q96JG9
LVHGQGFQGTAAIWP

ZACN

21

Q401N2
VENKVGGIPGWQALL

TTC28

1771

Q96AY4
GTWPAGQVLQAGELV

ZBTB17

761

Q13105
HIAGYWKQVGPIAVG

WLS

331

Q5T9L3
VLNGGFRNWLKEGHP

TST

126

Q16762
NPNCLVGIGEHIWLG

USP48

51

Q86UV5
VWNGVEVGGVHIQTG

USP40

621

Q9NVE5
GTVGLWQFLHGQCPG

UHRF1BP1

1226

Q6BDS2
TPWQLSQVVDGGGIG

PTGR2

66

Q8N8N7
QGAAHGPLGFWDERV

XRCC3

266

O43542
VLGGSGGPVLQTWLQ

TRPM4

121

Q8TD43
PRAVGKAGQGAGVVW

ZNF628

761

Q5EBL2
GRAVCGGVLVHPQWV

KLK3

46

P07288
GQILPQLGKDWTHQG

LPIN2

701

Q92539
AQAGLVGPGHVWLVP

GRIN2C

241

Q14957