Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXA9 NFIX MAFA NR1H3 POU4F1 POU4F3 ZNF319 FOXA2 MEIS1 MEIS2 ZIC2	8.49e-08	560	49	11	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	HOXA9 NFIX MAFA NR1H3 POU4F1 POU4F3 ZNF319 FOXA2 MEIS1 MEIS2 ZIC2	9.45e-08	566	49	11	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXA9 ZFP3 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 SIM2 ZNF319 FOXA2 ZKSCAN5 MEIS1 MEIS2 ZIC2	8.16e-07	1412	49	15	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXA9 ZFP3 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 ZNF319 FOXA2 ZKSCAN5 MEIS1 MEIS2 ZIC2	1.06e-06	1244	49	14	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXA9 ZFP3 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 SIM2 ZNF319 FOXA2 ZKSCAN5 MEIS1 MEIS2 ZIC2	1.23e-06	1459	49	15	GO:0000977
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HOXA9 ZFP3 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 ZNF319 FOXA2 ZKSCAN5 MEIS1 MEIS2 ZIC2	1.37e-06	1271	49	14	GO:0000987
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC39A6 SLC39A10	4.52e-04	13	49	2	GO:0140410
GeneOntologyMolecularFunction	glucosidase activity	MOGS GAA	6.07e-04	15	49	2	GO:0015926
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC39A6 SLC39A10	1.57e-03	24	49	2	GO:0005385
GeneOntologyMolecularFunction	chromatin binding	NFIX FOXP1 NR1H3 POU4F1 FOXA2 MEIS1 ZIC2	2.05e-03	739	49	7	GO:0003682
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC39A6 SLC39A10	2.79e-03	32	49	2	GO:0015106
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	HOXA9 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 ZNF319 FOXA2 MED7 MEIS1 MEIS2 ZIC2	1.49e-05	1390	49	13	GO:0045944
GeneOntologyBiologicalProcess	brain development	SZT2 NFIX FOXP1 POU4F1 SCRIB FOXA2 MEIS1 MEIS2 MAPK8IP3 ZIC2	2.79e-05	859	49	10	GO:0007420
GeneOntologyBiologicalProcess	pattern specification process	HOXA9 RTTN SIM2 FOXA2 MEIS1 MEIS2 RNF111 ZIC2	3.05e-05	526	49	8	GO:0007389
GeneOntologyBiologicalProcess	head development	SZT2 NFIX FOXP1 POU4F1 SCRIB FOXA2 MEIS1 MEIS2 MAPK8IP3 ZIC2	4.95e-05	919	49	10	GO:0060322
GeneOntologyBiologicalProcess	axonogenesis	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 MAPK8IP3 ZIC2	5.12e-05	566	49	8	GO:0007409
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 SCRIB MAPK8IP3 ZIC2	5.78e-05	748	49	9	GO:0048667
GeneOntologyBiologicalProcess	regulation of myeloid cell differentiation	HOXA9 FOXP1 POU4F1 MEIS1 MEIS2 NCKAP1L	5.94e-05	288	49	6	GO:0045637
GeneOntologyBiologicalProcess	embryonic pattern specification	SIM2 FOXA2 MEIS1 MEIS2	6.45e-05	91	49	4	GO:0009880
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 MAPK8IP3 ZIC2 NCKAP1L	9.86e-05	802	49	9	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 MAPK8IP3 ZIC2 NCKAP1L	1.16e-04	819	49	9	GO:0120039
GeneOntologyBiologicalProcess	axon development	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 MAPK8IP3 ZIC2	1.23e-04	642	49	8	GO:0061564
GeneOntologyBiologicalProcess	cell projection morphogenesis	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 MAPK8IP3 ZIC2 NCKAP1L	1.23e-04	826	49	9	GO:0048858
GeneOntologyBiologicalProcess	neuron fate specification	NFIX POU4F1 FOXA2	1.36e-04	42	49	3	GO:0048665
GeneOntologyBiologicalProcess	positive regulation of B cell receptor signaling pathway	FOXP1 SLC39A10	2.46e-04	10	49	2	GO:0050861
GeneOntologyBiologicalProcess	zinc ion import across plasma membrane	SLC39A6 SLC39A10	3.00e-04	11	49	2	GO:0071578
GeneOntologyBiologicalProcess	myeloid cell differentiation	HOXA9 NFIX FOXP1 POU4F1 MEIS1 MEIS2 NCKAP1L	3.28e-04	558	49	7	GO:0030099
GeneOntologyBiologicalProcess	cell morphogenesis	SZT2 UNC5B NFIX FOXP1 POU4F1 POU4F3 SCRIB MAPK8IP3 ZIC2 NCKAP1L	4.22e-04	1194	49	10	GO:0000902
GeneOntologyBiologicalProcess	central nervous system development	SZT2 NFIX FOXP1 POU4F1 SCRIB FOXA2 MEIS1 MEIS2 MAPK8IP3 ZIC2	4.30e-04	1197	49	10	GO:0007417
GeneOntologyBiologicalProcess	embryo development	HOXA9 SPEG FOXP1 POU4F3 SCRIB SIM2 FOXA2 MEIS1 MEIS2 MAPK8IP3 ZIC2	4.48e-04	1437	49	11	GO:0009790
GeneOntologyBiologicalProcess	endothelial cell activation	HOXA9 FOXP1	4.94e-04	14	49	2	GO:0042118
GeneOntologyBiologicalProcess	axon guidance	UNC5B FOXP1 POU4F3 MAPK8IP3 ZIC2	5.64e-04	285	49	5	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	UNC5B FOXP1 POU4F3 MAPK8IP3 ZIC2	5.73e-04	286	49	5	GO:0097485
GeneOntologyCellularComponent	transcription regulator complex	HOXA9 NR1H3 POU4F1 POU4F3 FOXA2 MED7 TRRAP MEIS1	6.70e-05	596	49	8	GO:0005667
GeneOntologyCellularComponent	chromatin	HOXA9 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 SIM2 FOXA2 TRRAP MEIS1 MEIS2	1.20e-04	1480	49	12	GO:0000785
Domain	PKNOX/Meis_N	MEIS1 MEIS2	6.44e-05	5	48	2	IPR032453
Domain	Meis_PKNOX_N	MEIS1 MEIS2	6.44e-05	5	48	2	PF16493
Domain	Homeobox	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	3.26e-04	234	48	5	PF00046
Domain	HOMEOBOX_1	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	3.40e-04	236	48	5	PS00027
Domain	HOX	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	3.46e-04	237	48	5	SM00389
Domain	HOMEOBOX_2	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	3.60e-04	239	48	5	PS50071
Domain	Homeobox_dom	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	3.60e-04	239	48	5	IPR001356
Domain	Zip	SLC39A6 SLC39A10	5.77e-04	14	48	2	PF02535
Domain	ZIP	SLC39A6 SLC39A10	5.77e-04	14	48	2	IPR003689
Domain	POU	POU4F1 POU4F3	7.58e-04	16	48	2	SM00352
Domain	POU_2	POU4F1 POU4F3	7.58e-04	16	48	2	PS00465
Domain	POU_dom	POU4F1 POU4F3	7.58e-04	16	48	2	IPR000327
Domain	POU_3	POU4F1 POU4F3	7.58e-04	16	48	2	PS51179
Domain	Pou	POU4F1 POU4F3	7.58e-04	16	48	2	PF00157
Domain	POU_1	POU4F1 POU4F3	7.58e-04	16	48	2	PS00035
Domain	-	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	7.75e-04	283	48	5	1.10.10.60
Domain	Homeobox_KN	MEIS1 MEIS2	8.58e-04	17	48	2	PF05920
Domain	POU	POU4F1 POU4F3	8.58e-04	17	48	2	IPR013847
Domain	Homeobox_KN_domain	MEIS1 MEIS2	8.58e-04	17	48	2	IPR008422
Domain	Homeodomain-like	HOXA9 POU4F1 POU4F3 MEIS1 MEIS2	1.58e-03	332	48	5	IPR009057
Domain	-	POU4F1 POU4F3	2.18e-03	27	48	2	1.10.260.40
Domain	Lambda_DNA-bd_dom	POU4F1 POU4F3	2.51e-03	29	48	2	IPR010982
Domain	TF_fork_head_CS_2	FOXP1 FOXA2	6.23e-03	46	48	2	IPR030456
Domain	TF_fork_head_CS_1	FOXP1 FOXA2	6.49e-03	47	48	2	IPR018122
Domain	FH	FOXP1 FOXA2	7.04e-03	49	48	2	SM00339
Domain	FORK_HEAD_1	FOXP1 FOXA2	7.04e-03	49	48	2	PS00657
Domain	FORK_HEAD_2	FOXP1 FOXA2	7.04e-03	49	48	2	PS00658
Domain	Fork_head_dom	FOXP1 FOXA2	7.04e-03	49	48	2	IPR001766
Domain	FORK_HEAD_3	FOXP1 FOXA2	7.04e-03	49	48	2	PS50039
Domain	Forkhead	FOXP1 FOXA2	7.04e-03	49	48	2	PF00250
Domain	zf-RING_2	RNF43 RNF111	7.90e-03	52	48	2	PF13639
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXA9 NFIX MAFA FOXP1 NR1H3 POU4F1 POU4F3 FOXA2 MEIS1 MEIS2 ZIC2	4.26e-08	908	49	11	19274049
Pubmed	A conserved non-homeodomain Hoxa9 isoform interacting with CBP is co-expressed with the 'typical' Hoxa9 protein during embryogenesis.	HOXA9 MEIS1 MEIS2	5.24e-08	6	49	3	15161102
Pubmed	Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes.	HOXA9 MEIS1 MEIS2	5.24e-08	6	49	3	11438208
Pubmed	Global control of motor neuron topography mediated by the repressive actions of a single hox gene.	HOXA9 FOXP1 MEIS1 MEIS2	1.98e-07	36	49	4	20826310
Pubmed	Proximo-distal positional information encoded by an Fgf-regulated gradient of homeodomain transcription factors in the vertebrate limb.	HOXA9 MEIS1 MEIS2	2.19e-07	9	49	3	32537491
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NFIX ANKRD28 FOXP1 SCRIB SIM2 FOXA2 TRRAP MEIS1 GAA ZIC2	2.70e-07	857	49	10	25609649
Pubmed	Identification of a new family of Pbx-related homeobox genes.	HOXA9 MEIS1 MEIS2	3.13e-07	10	49	3	8950991
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	HOXA9 NKD2 FOXP1 NR1H3 POU4F1 MED7 ZKSCAN5 MEIS1 MEIS2 ZIC2	3.33e-07	877	49	10	20211142
Pubmed	The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells.	POU4F1 POU4F3 ZIC2	4.30e-07	11	49	3	28009286
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	HOXA9 RPL27A NKD2 MOGS MAFA SLC39A6 FASTKD2 SLC39A10 ZNF319 FOXA2 RNF111	7.06e-07	1203	49	11	29180619
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	HOXA9 NFIX MAFA FOXP1 POU4F1 POU4F3 FOXA2 MEIS2	8.74e-07	544	49	8	28473536
Pubmed	Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.	HOXA9 MEIS1	1.94e-06	2	49	2	14701735
Pubmed	HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis.	HOXA9 MEIS1	1.94e-06	2	49	2	19620287
Pubmed	A pro B cell population forms the apex of the leukemic hierarchy in Hoxa9/Meis1-dependent AML.	HOXA9 MEIS1	1.94e-06	2	49	2	36517672
Pubmed	High glucose level promotes migration behavior of breast cancer cells through zinc and its transporters.	SLC39A6 SLC39A10	1.94e-06	2	49	2	24587242
Pubmed	Myeloid ecotropic viral integration site 1 (MEIS) 1 involvement in embryonic implantation.	MEIS1 MEIS2	1.94e-06	2	49	2	18408019
Pubmed	Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation.	HOXA9 MEIS1	1.94e-06	2	49	2	16469876
Pubmed	Moderate zinc deficiency reduces testicular Zip6 and Zip10 abundance and impairs spermatogenesis in mice.	SLC39A6 SLC39A10	1.94e-06	2	49	2	21248196
Pubmed	Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors.	MEIS1 MEIS2	1.94e-06	2	49	2	34035267
Pubmed	Entospletinib in Combination with Induction Chemotherapy in Previously Untreated Acute Myeloid Leukemia: Response and Predictive Significance of HOXA9 and MEIS1 Expression.	HOXA9 MEIS1	1.94e-06	2	49	2	32820015
Pubmed	HOXA9 and MEIS1 gene overexpression in the diagnosis of childhood acute leukemias: Significant correlation with relapse and overall survival.	HOXA9 MEIS1	1.94e-06	2	49	2	26059450
Pubmed	Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration.	SLC39A6 SLC39A10	1.94e-06	2	49	2	27274087
Pubmed	POU4F3 Is Necessary for Normal Merkel Cell Formation, whereas POU4F1 Is Dispensable.	POU4F1 POU4F3	1.94e-06	2	49	2	39009281
Pubmed	MEIS1 and MEIS2 Expression and Prostate Cancer Progression: A Role For HOXB13 Binding Partners in Metastatic Disease.	MEIS1 MEIS2	1.94e-06	2	49	2	29716922
Pubmed	Meis1-mediated apoptosis is caspase dependent and can be suppressed by coexpression of HoxA9 in murine and human cell lines.	HOXA9 MEIS1	1.94e-06	2	49	2	15479723
Pubmed	Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.	POU4F1 POU4F3	1.94e-06	2	49	2	8248179
Pubmed	Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfrα Genes.	FOXP1 MEIS1 MEIS2	2.11e-06	18	49	3	26904955
Pubmed	Shox2 regulates progression through chondrogenesis in the mouse proximal limb.	HOXA9 MEIS1 MEIS2	2.51e-06	19	49	3	23038774
Pubmed	Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.	UNC5B MEIS1 MEIS2	3.97e-06	22	49	3	37823339
Pubmed	MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus.	SCRIB MEIS1 MEIS2	3.97e-06	22	49	3	34032267
Pubmed	The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis.	SLC39A6 SLC39A10	5.83e-06	3	49	2	32797246
Pubmed	Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development.	MEIS1 MEIS2	5.83e-06	3	49	2	18216174
Pubmed	Silencing Nfix rescues muscular dystrophy by delaying muscle regeneration.	SGCA NFIX	5.83e-06	3	49	2	29057908
Pubmed	DNA-dependent formation of transcription factor pairs alters their binding specificity.	MEIS1 MEIS2	5.83e-06	3	49	2	26550823
Pubmed	MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet.	SGCA NFIX	5.83e-06	3	49	2	38205246
Pubmed	miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.	HOXA9 MEIS1	5.83e-06	3	49	2	22353710
Pubmed	Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes.	HOXA9 MEIS1	5.83e-06	3	49	2	16648484
Pubmed	Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems.	POU4F1 POU4F3	5.83e-06	3	49	2	9598366
Pubmed	Gene expression profiling of Polycomb, Hox and Meis genes in patients with acute myeloid leukaemia.	HOXA9 MEIS1	5.83e-06	3	49	2	18410541
Pubmed	The deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesis.	HOXA9 MEIS1	5.83e-06	3	49	2	24809472
Pubmed	Conserved regulation of proximodistal limb axis development by Meis1/Hth.	MEIS1 MEIS2	5.83e-06	3	49	2	10586884
Pubmed	Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.	MAFA FOXA2	5.83e-06	3	49	2	18753309
Pubmed	Pioneer factor Foxa2 enables ligand-dependent activation of type II nuclear receptors FXR and LXRα.	NR1H3 FOXA2	5.83e-06	3	49	2	34246806
Pubmed	Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia.	HOXA9 MEIS1	5.83e-06	3	49	2	25911551
Pubmed	Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse.	POU4F1 POU4F3	5.83e-06	3	49	2	21935940
Pubmed	Enforced expression of NUP98-HOXA9 in human CD34(+) cells enhances stem cell proliferation.	HOXA9 MEIS1	5.83e-06	3	49	2	17178874
Pubmed	Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.	POU4F1 POU4F3	5.83e-06	3	49	2	8290353
Pubmed	Dangerous liaisons: cooperation between Pbx3, Meis1 and Hoxa9 in leukemia.	HOXA9 MEIS1	5.83e-06	3	49	2	26130510
Pubmed	The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons.	POU4F1 POU4F3	5.83e-06	3	49	2	7623109
Pubmed	Systematic identification of intergenic long-noncoding RNAs in mouse retinas using full-length isoform sequencing.	POU4F1 POU4F3	5.83e-06	3	49	2	31286854
Pubmed	The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.	POU4F1 POU4F3	5.83e-06	3	49	2	7935408
Pubmed	Expression of HOX genes in acute leukemia cell lines with and without MLL translocations.	HOXA9 MEIS1	5.83e-06	3	49	2	15160920
Pubmed	FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3.	FOXP1 FOXA2	5.83e-06	3	49	2	20175877
Pubmed	Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.	POU4F1 POU4F3	5.83e-06	3	49	2	8162704
Pubmed	Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.	NFIX FOXA2 MAPK8IP3	5.91e-06	25	49	3	18324732
Pubmed	Meis homeobox genes control progenitor competence in the retina.	POU4F1 MEIS1 MEIS2	5.91e-06	25	49	3	33723039
Pubmed	Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi.	POU4F1 POU4F3 MEIS2	8.40e-06	28	49	3	38344749
Pubmed	Multiple roles of mesenchymal beta-catenin during murine limb patterning.	HOXA9 MEIS1 MEIS2	1.04e-05	30	49	3	16495310
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	FOXP1 FOXA2 MEIS2	1.04e-05	30	49	3	25804738
Pubmed	Molecular mechanism of synovial joint site specification and induction in developing vertebrate limbs.	MEIS1 MEIS2	1.16e-05	4	49	2	37272420
Pubmed	Expression patterns of homeobox genes in the mouse vomeronasal organ at postnatal stages.	MEIS1 MEIS2	1.16e-05	4	49	2	27521061
Pubmed	Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.	POU4F1 POU4F3	1.16e-05	4	49	2	9256502
Pubmed	FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.	MAFA FOXA2	1.16e-05	4	49	2	16847327
Pubmed	Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.	POU4F1 POU4F3	1.16e-05	4	49	2	33135183
Pubmed	Transcription factor AP-2α regulates acute myeloid leukemia cell proliferation by influencing Hoxa gene expression.	HOXA9 MEIS1	1.16e-05	4	49	2	23660297
Pubmed	Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1.	HOXA9 MEIS1	1.16e-05	4	49	2	12082612
Pubmed	HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation.	HOXA9 MEIS1	1.16e-05	4	49	2	15681849
Pubmed	Upregulation of Flt3 is a passive event in Hoxa9/Meis1-induced acute myeloid leukemia in mice.	HOXA9 MEIS1	1.16e-05	4	49	2	27617578
Pubmed	A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition.	SLC39A6 SLC39A10	1.16e-05	4	49	2	28098160
Pubmed	Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.	POU4F1 POU4F3	1.16e-05	4	49	2	20826176
Pubmed	Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120.	MOGS GAA	1.16e-05	4	49	2	8416962
Pubmed	c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.	HOXA9 MEIS1	1.16e-05	4	49	2	16507773
Pubmed	Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.	HOXA9 MEIS1	1.16e-05	4	49	2	21518888
Pubmed	Inhibition of human immunodeficiency virus syncytium formation and virus replication by castanospermine.	MOGS GAA	1.16e-05	4	49	2	2825177
Pubmed	Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.	POU4F1 POU4F3	1.16e-05	4	49	2	24116103
Pubmed	Identification of a conserved family of Meis1-related homeobox genes.	MEIS1 MEIS2	1.16e-05	4	49	2	9049632
Pubmed	The nuclear oncoprotein TLX1/HOX11 associates with pericentromeric satellite 2 DNA in leukemic T-cells.	MEIS1 MEIS2	1.16e-05	4	49	2	16357834
Pubmed	Functional genomics identifies therapeutic targets for MYC-driven cancer.	SPEG NR1H3 WEE2 TRRAP	1.39e-05	103	49	4	22623531
Pubmed	Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain.	FOXP1 POU4F1 FOXA2	1.82e-05	36	49	3	22278924
Pubmed	Effect of a glucosidase inhibitor on the bioactivity and immunoreactivity of human immunodeficiency virus type 1 envelope glycoprotein.	MOGS GAA	1.94e-05	5	49	2	1678778
Pubmed	Expression of Meis and Pbx genes and their protein products in the developing telencephalon: implications for regional differentiation.	MEIS1 MEIS2	1.94e-05	5	49	2	10842069
Pubmed	Nt mutation causing laterality defects associated with deletion of rotatin.	RTTN SOCS6	1.94e-05	5	49	2	17551791
Pubmed	Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity.	POU4F1 ZIC2	1.94e-05	5	49	2	19004857
Pubmed	Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding.	POU4F1 ZIC2	1.94e-05	5	49	2	35988153
Pubmed	Hoxa2 selectively enhances Meis binding to change a branchial arch ground state.	MEIS1 MEIS2	1.94e-05	5	49	2	25640223
Pubmed	HOX cofactors expression and regulation in the human ovary.	MEIS1 MEIS2	1.94e-05	5	49	2	18973687
Pubmed	Dental Epithelial Stem Cells Express the Developmental Regulator Meis1.	MEIS1 MEIS2	1.94e-05	5	49	2	30914971
Pubmed	Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice.	SCRIB FOXA2	1.94e-05	5	49	2	25128525
Pubmed	Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice.	POU4F1 ZIC2	1.94e-05	5	49	2	24885435
Pubmed	HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells.	HOXA9 MEIS1	1.94e-05	5	49	2	10082572
Pubmed	N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with changes in antibody recognition of the V1/V2 region of gp120.	MOGS GAA	1.94e-05	5	49	2	8794361
Pubmed	N-butyldeoxynojirimycin-mediated inhibition of human immunodeficiency virus entry correlates with impaired gp120 shedding and gp41 exposure.	MOGS GAA	1.94e-05	5	49	2	8794362
Pubmed	Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.	POU4F1 POU4F3	1.94e-05	5	49	2	8637595
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	FOXP1 POU4F3 TRRAP	2.14e-05	38	49	3	28218735
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	HOXA9 ZSWIM8 ANKRD28 FOXP1 SCRIB TRRAP ZKSCAN5 RNF43 ZIC2	2.26e-05	1116	49	9	31753913
Pubmed	N-Glycans in the gp120 V1/V2 domain of the HIV-1 strain NL4-3 are indispensable for viral infectivity and resistance against antibody neutralization.	MOGS GAA	2.91e-05	6	49	2	16547752
Pubmed	Inhibition of HIV and SIV infectivity by blockade of alpha-glucosidase activity.	MOGS GAA	2.91e-05	6	49	2	1704656
Pubmed	The Wilms' tumor gene Wt1 is required for normal development of the retina.	POU4F1 POU4F3	2.91e-05	6	49	2	11889045
Pubmed	Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design.	MOGS GAA	2.91e-05	6	49	2	12719582
Pubmed	MEIS proteins as partners of the TLX1/HOX11 oncoprotein.	MEIS1 MEIS2	2.91e-05	6	49	2	19559479
Cytoband	18q22.2	RTTN SOCS6	2.34e-05	7	49	2	18q22.2
Cytoband	3p25.1	FBLN2 ANKRD28	6.49e-04	35	49	2	3p25.1
Cytoband	17q22	CACNA1G RNF43	1.03e-03	44	49	2	17q22
Cytoband	Ensembl 112 genes in cytogenetic band chr18q22	RTTN SOCS6	2.36e-03	67	49	2	chr18q22
GeneFamily	POU class homeoboxes and pseudogenes	POU4F1 POU4F3	9.50e-04	23	36	2	523
GeneFamily	TALE class homeoboxes and pseudogenes	MEIS1 MEIS2	1.22e-03	26	36	2	526
GeneFamily	Forkhead boxes	FOXP1 FOXA2	3.31e-03	43	36	2	508
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	UNC5B SPEG LRRC4B	3.99e-03	161	36	3	593
GeneFamily	Olfactory receptors, family 52	OR52E5 OR52P1	4.27e-03	49	36	2	165
Coexpression	GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	MOGS SZT2 SIM2 TRRAP FHIP2B	3.15e-05	199	48	5	M7254
Coexpression	GSE360_L_DONOVANI_VS_L_MAJOR_DC_UP	SGCA UNC5B NR1H3 DMXL1 ZIC2	3.23e-05	200	48	5	M5192
Coexpression	WANG_HCP_PROSTATE_CANCER	SOCS6 SIM2 MEIS2 MAPK8IP3	4.29e-05	106	48	4	M17044
ToppCell	facs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 MOGS NFIX MEIS1 GAA	2.04e-06	189	49	5	533685a921a65d84107d8d33c43b4fffde019143
ToppCell	facs-Marrow-KLS-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 MOGS NFIX MEIS1 GAA	2.04e-06	189	49	5	dca56ab02bf0505f9a352ff907edaef30906d854
ToppCell	facs-Marrow-KLS-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 MOGS NFIX MEIS1 GAA	2.09e-06	190	49	5	a513c1e7df62c28128c932a68b252ee8f0255172
ToppCell	facs-Marrow-KLS-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 MOGS NFIX MEIS1 GAA	2.14e-06	191	49	5	51327ba28b2e3052087fa0fc9b7c0339dc09a1e3
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 MOGS SLC39A6 MEIS1 GAA	2.31e-06	194	49	5	c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RPL27A FBLN2 MEIS1 MEIS2 GAA	2.37e-06	195	49	5	def0a3fb36eec6fbb08e1323baf2b22b28bf751a
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 SLC39A6 FOXP1 MEIS1 MEIS2	2.49e-06	197	49	5	fc718a254bda4df2d62975d04393492fb75ab305
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 SLC39A6 FOXP1 MEIS1 MEIS2	2.49e-06	197	49	5	c7b33d64e5cba3a8fc6f2d6aa85ebc83893195de
ToppCell	3'-GW_trimst-1-LargeIntestine\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 SLC39A6 FOXP1 MEIS1 MEIS2	2.56e-06	198	49	5	ea6621a148a96c8ffa1a93a35c9e288545d2637a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 CASKIN1 FOXP1 MEIS2	3.57e-05	169	49	4	f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 ZFP3 SZT2 UNC5B	3.65e-05	170	49	4	55fe16d98ea284d05fb899888e4569c685644c7b
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NKD2 SGCA UNC5B MEIS1	3.91e-05	173	49	4	75e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NKD2 SGCA UNC5B MEIS1	3.91e-05	173	49	4	26e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCA SPEG CASKIN1 CACNA1G	4.56e-05	180	49	4	a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCA SPEG CASKIN1 CACNA1G	4.56e-05	180	49	4	63a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell	systemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HOXA9 ANKRD28 MEIS1 MEIS2	4.66e-05	181	49	4	070ae3f3fe0e177fabcf34e64a0f158b01354837
ToppCell	COVID-19_Convalescent-CD8+_T_naive\|COVID-19_Convalescent / Disease condition and Cell class	RPL27A SGCA SPEG FOXP1	5.07e-05	185	49	4	2f8277a0b58fb0c49fa76ff6dfa6da961da1f9f5
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN2 UNC5B FOXP1 MEIS2	5.29e-05	187	49	4	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	systemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HOXA9 ANKRD28 MEIS1 MEIS2	5.51e-05	189	49	4	6687a93ac8540ece5fd762f6f77c1f25f159195b
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBLN2 UNC5B FOXP1 MEIS2	5.51e-05	189	49	4	360f09f46231a83f99d8fa0158b72a38068e1642
ToppCell	facs-Marrow-KLS-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 NFIX MEIS1 GAA	5.63e-05	190	49	4	11f32f46661e44770782b8ec13c00028e1dfc3cd
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 UNC5B FOXP1 MEIS2	5.63e-05	190	49	4	d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 NFIX MEIS1 GAA	5.63e-05	190	49	4	96a9756cad5468a12591021e6d661ed269b5b3d9
ToppCell	facs-Marrow-KLS-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 NFIX MEIS1 GAA	5.63e-05	190	49	4	20f4f6fe09345878484086047061d6f900f9d476
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	SGCA SPEG MEIS1 MEIS2	5.74e-05	191	49	4	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 NFIX MEIS1 MEIS2	5.86e-05	192	49	4	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXA9 MOGS MEIS1 GAA	5.86e-05	192	49	4	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 NFIX MEIS1 MEIS2	6.10e-05	194	49	4	54a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HOXA9 NFIX POU4F1 MEIS2	6.10e-05	194	49	4	4e93bd903cddfd0c8f220b6a35b449895de4119b
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 NFIX MEIS1 MEIS2	6.10e-05	194	49	4	da926441053b499cb5107ccb116fb1b3844d82b7
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 NFIX MEIS1 MEIS2	6.10e-05	194	49	4	f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NFIX FOXP1 MEIS2 GAA	6.22e-05	195	49	4	febe746099964b9ea9e75f2efc72c962c01f0421
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 FOXP1 MEIS1 MEIS2	6.35e-05	196	49	4	fd0a2b863dedaf08d18e7f67da18ac7e853991e4
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 NFIX MEIS1 MEIS2	6.35e-05	196	49	4	cbfe01ba8071864e19b37028236ae35789f630fe
ToppCell	COPD-Stromal\|COPD / Disease state, Lineage and Cell class	FBLN2 NKD2 SGCA MEIS1	6.47e-05	197	49	4	d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 CACNA1G MEIS1 MEIS2	6.47e-05	197	49	4	9af431323da6d099459b7360af40e5df998cffbd
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NKD2 NFIX CACNA1G SIM2	6.47e-05	197	49	4	3fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 FBLN2 MEIS1 MEIS2	6.60e-05	198	49	4	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NKD2 TMEM45B UNC5B SLC39A10	6.60e-05	198	49	4	72e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 CACNA1G MEIS1 MEIS2	6.60e-05	198	49	4	a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	FBLN2 NKD2 MEIS1 MEIS2	6.73e-05	199	49	4	675f7c56b03a7918e2d9ca99440df6f27ad8e838
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NKD2 TMEM45B UNC5B SLC39A10	6.73e-05	199	49	4	9c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	FBLN2 NKD2 SGCA MEIS1	6.73e-05	199	49	4	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	FBLN2 NKD2 MEIS1 MEIS2	6.73e-05	199	49	4	97d74985018816754d11a55b9fb689690ecb1374
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NKD2 TMEM45B UNC5B SLC39A10	6.73e-05	199	49	4	72b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	FBLN2 NKD2 SGCA MEIS1	6.86e-05	200	49	4	954fee8425673e76198be414f5f6c4e3597c1919
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	TMEM45B UNC5B PTPN23 MEIS1	6.86e-05	200	49	4	a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	FBLN2 NKD2 MEIS1 MEIS2	6.86e-05	200	49	4	c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FBLN2 NKD2 CACNA1G MEIS1	6.86e-05	200	49	4	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	Thalamus\|World / BrainAtlas - Mouse McCarroll V32	POU4F1 SOCS6 ZIC2	2.82e-04	116	49	3	5ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCell	TCGA-Brain-Recurrent_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	NKD2 MAFA FOXA2	4.12e-04	132	49	3	6a6718582edfc59c63f2c8f753be81e0f4a7246b
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TMEM45B SPEG RNF43	4.69e-04	138	49	3	97f5dc17522462133e582b508ad0ef036e656872
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	UNC5B MAFA MEIS2	5.10e-04	142	49	3	4ac3b285adfe80c47861943cf8c6188106cb3ba8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NKD2 MEIS1 MEIS2	5.42e-04	145	49	3	051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1G MEIS1 MEIS2	5.98e-04	150	49	3	909ccab92855f5f049dc29593aadab1ea973297b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SGCA SPEG LRRC4B	6.21e-04	152	49	3	ee329249a034a969a16b26a224aa04249d67382d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SGCA SPEG LRRC4B	6.21e-04	152	49	3	bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN2 ZFP3 MEIS2	6.46e-04	154	49	3	1899138c096c08d8aee6b1970b7c0081e14c88a8
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	DDHD1 TRRAP RNF111	6.58e-04	155	49	3	a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell	NS-moderate-d_07-13-Myeloid-Mast_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HOXA9 FBLN2 FOXP1	6.70e-04	156	49	3	17c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCell	COVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	HOXA9 ANKRD28 MEIS1	6.95e-04	158	49	3	0d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZSWIM8 ZNF319 GAA	7.08e-04	159	49	3	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SGCA SPEG LRRC4B	7.08e-04	159	49	3	7cda111bb98f1241989e49d490bdf51a712ea589
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HOXA9 RPL27A FBLN2	7.08e-04	159	49	3	210ac7fa89514a84f38d9f42254e38fbc2bc5f42
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	NKD2 SIM2 MEIS1	7.08e-04	159	49	3	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HOXA9 RPL27A FBLN2	7.21e-04	160	49	3	c9fe3438f747e2a98e3f27a56ba4c12a3789c2f2
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SGCA CACNA1G SIM2	7.34e-04	161	49	3	9703b7e67d9fadb6129cad166bd01be915042e44
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 MEIS2 DMXL1	7.34e-04	161	49	3	deb10628d258fb813c293f81fb71be8e383dc82a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 MEIS2 DMXL1	7.34e-04	161	49	3	8aaca49b53a551395f4025ac4e535c7b0ce41a49
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC4B MEIS1 MEIS2	7.34e-04	161	49	3	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1G MEIS1 MEIS2	7.48e-04	162	49	3	5f009b231f21861afee9cc0c569082e1135f929c
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SPEG DDHD1 FOXP1	7.48e-04	162	49	3	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1G MEIS1 MEIS2	7.48e-04	162	49	3	b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FBLN2 TRRAP GAA	7.61e-04	163	49	3	63b0badaee3b2d827b1f4524510e3384d8f8fcde
ToppCell	IIF-Other-HSPC\|IIF / Disease, Lineage and Cell Type	HOXA9 NKD2 ANKRD28	7.61e-04	163	49	3	1e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5B LRRC4B MEIS1	7.75e-04	164	49	3	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC5B MEIS2 ZIC2	7.75e-04	164	49	3	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC5B MEIS2 ZIC2	7.75e-04	164	49	3	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPEG LRRC4B MEIS1	7.75e-04	164	49	3	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC5B MEIS2 ZIC2	7.75e-04	164	49	3	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC5B MEIS2 ZIC2	7.75e-04	164	49	3	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	HOXA9 FOXA2 MEIS1	7.88e-04	165	49	3	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SGCA SPEG MEIS1	7.88e-04	165	49	3	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN2 UNC5B MEIS2	7.88e-04	165	49	3	a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	UNC5B NFIX RTTN	8.02e-04	166	49	3	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN2 ANKRD28 MEIS2	8.02e-04	166	49	3	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANKRD28 FOXP1 NCKAP1L	8.16e-04	167	49	3	a813b95c2fafb638b249bc4fa4f708c6f39ad444
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAFA FOXP1 ZIC2	8.16e-04	167	49	3	3c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCell	facs-Kidney-nan-24m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAFA FOXP1 ZIC2	8.16e-04	167	49	3	28e9670586ff551b700c794313d27eedbfa1286b
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	HOXA9 FBLN2 MEIS2	8.31e-04	168	49	3	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	Adult-Mesenchymal-chondrocyte-D175\|Adult / Lineage, Cell type, age group and donor	FBLN2 NKD2 MEIS1	8.31e-04	168	49	3	14071b961c9bdb54a8259b12a88237b802cbde36
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 FOXP1 MEIS2	8.45e-04	169	49	3	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	POU4F3 MEIS1 ZIC2	8.45e-04	169	49	3	6ff1172da690ca17f7108f1617b255b766971a57
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 FOXP1 MEIS2	8.45e-04	169	49	3	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN2 SPEG MEIS2	8.45e-04	169	49	3	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HOXA9 NFIX RNF43	8.59e-04	170	49	3	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-CLP\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 ANKRD28 NCKAP1L	8.59e-04	170	49	3	8d6419ffe7dc1a0483c174d8e4b29704895eb9cf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG MEIS1 MEIS2	8.59e-04	170	49	3	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAFA WEE2 RNF43	8.59e-04	170	49	3	985c2d5962100fab0d95bee39f382ccbe799331e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG MEIS1 MEIS2	8.59e-04	170	49	3	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
Disease	Ovarian Mucinous Adenocarcinoma	SPEG WEE2 TRRAP	1.76e-05	31	48	3	C1335167
Disease	Gastric Adenocarcinoma	SPEG WEE2 TRRAP	5.46e-05	45	48	3	C0278701
Disease	restless legs syndrome (implicated_via_orthology)	MEIS1 MEIS2	7.21e-05	8	48	2	DOID:0050425 (implicated_via_orthology)
Disease	Intellectual Disability	RTTN PTPN23 CACNA1G TRRAP MEIS2 MAPK8IP3	8.37e-05	447	48	6	C3714756
Disease	leukemia (implicated_via_orthology)	MEIS1 MEIS2	4.35e-04	19	48	2	DOID:1240 (implicated_via_orthology)
Disease	Global developmental delay	SZT2 TRRAP MAPK8IP3	1.34e-03	133	48	3	C0557874

Protein segments in the cluster

Peptide	Gene	Start	Entry
ISPLHLAAYHGHHQA	ANKRD28	551	O15084
TGYLPHQQDPHHVHR	DMXL1	331	Q9Y485
IQEVHAHYLHQRPLH	PTPN23	1371	Q9H3S7
VEALHAYVSIHHPHD	NR1H3	386	Q13133
VHHLNHGPPLHSHQY	MEIS1	36	O00470
HHHQALEPGDLLDHI	POU4F1	106	Q01851
HIPLHLAAQHGHYDV	CASKIN1	116	Q8WXD9
HPTIRYHHHHGQDSL	NFIX	386	Q14938
HHGAHHPAAAAAYEA	MAFA	151	Q8NHW3
NYHLMDLGHPHHSIR	MAPK8IP3	1036	Q9UPT6
HGPPLHATQHYGAHA	MEIS2	41	O14770
HATQHYGAHAPHPNV	MEIS2	46	O14770
FVHVHHLINEYRPHQ	MED7	116	O43513
HAGHKYAAGHTVHLP	FBLN2	141	P98095
HTLYAHLIGHCDHLS	FHIP2B	431	Q86V87
LSHEEHPHSHPLYGH	FOXP1	291	Q9H334
HAAGANAVPAAVYHH	HOXA9	71	P31269
EYPHLKNHGLHHCNS	NCKAP1L	586	P55160
FGHHVPVHIHILLAN	OR52P1	266	Q8NH57
EGYAVPVIQRHEHHH	NKD2	421	Q969F2
LHHYGHLEGPHQARA	MOGS	766	Q13724
HHHHYHLGNGTLRAP	CACNA1G	501	O43497
LPHLYTLFHQAHVAG	GAA	706	P10253
HLAPGTDDHNHHLAL	DDHD1	66	Q8NEL9
HEEHDHGPEALHRQH	SLC39A10	26	Q9ULF5
ALPALERDHLNHHHY	LRRC4B	651	Q9NT99
AAHPHHAQVHPAVAL	SCRIB	21	C0HLS1
GGLHHHRINFDKYHP	RPL27A	36	P46776
HRFGHNIPHYIHILL	OR52E5	261	Q8NH55
EAHLKPEHHYAFNHP	FOXA2	361	Q9Y261
YHLPVHVIGHHAVSP	RTTN	986	Q86VV8
HHPDGPHFGRNHIYQ	SZT2	3081	Q5T011
HFSKDVHLPHNYHID	FASTKD2	591	Q9NYY8
LIRQHPGHAHYHLPA	RNF43	341	Q68DV7
TAHQPLHHHLLQEYE	SIM2	141	Q14190
HPHHAVHQGLEGDLL	POU4F3	106	Q15319
HVAVPPAVHITYHAH	SGCA	51	Q16586
PAVHITYHAHLQGHP	SGCA	56	Q16586
GDAFLHLLPHSHASH	SLC39A6	371	Q13433
FVPDGPHLHLYHENH	TMEM45B	66	Q96B21
AHYHAPPRLHHLQLG	RNF111	831	Q6ZNA4
QGLDYLHGHHVLHLD	SPEG	3071	Q15772
YHNLRLSLHDLPHAH	UNC5B	751	Q8IZJ1
HYHQLHVHLQLLPSD	nan	61	Q6Q795
VNPHSLHHLHAAYRV	ZSWIM8	1656	A7E2V4
GQPSHLLYHQHVHTL	ZNF319	381	Q9P2F9
ALHEVYAHAVLGHHP	WEE2	256	P0C1S8
ATLLVEHAPHHIHDN	TRRAP	1836	Q9Y4A5
SHNGDLHLHLDEHVP	SOCS6	196	O14544
HLVQHHSVHSGERPY	ZKSCAN5	416	Q9Y2L8
LHHAHSDAQGHLLFP	ZIC2	146	O95409
HLIHHHRIHTGERPY	ZFP3	211	Q96NJ6